ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000182220
ATP6AP2
ATPase H+ transporting accessory protein 2
[ "O75787" ]
X
40579372-40606848
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA003156" ]
[ "APT6M8-9", "ATP6IP2", "ATP6M8-9", "M8-9", "PRR", "RENR" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[]
[ "Receptor" ]
[ "Congenital disorder of glycosylation", "Disease variant", "Epilepsy", "Intellectual disability", "Neurodegeneration", "Parkinsonism" ]
[]
[]
[]
[]
null
Approved
null
151
null
null
Cluster 29: Non-specific - Unknown function
Cluster 14: Neurons - Synaptic function
Cluster 36: Non-specific - mRNA processing
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 69: Parathyroid gland - Mixed function
Tissue enriched
Detected in all
4
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Skin Cutaneous Melanoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Skin Cutaneous Melanoma" ]
14,608
6
ENSG00000182223
ZAR1
Zygote arrest 1
[ "Q86SH2" ]
4
48490252-48494389
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "Z3CXXC6" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Differentiation", "Oogenesis" ]
[ "Developmental protein", "RNA-binding" ]
[]
[]
[]
[]
[]
null
null
null
1
null
null
null
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 41: Oocytes - Oogenesis
Cluster 75: Ovary - Mixed function
Tissue enhanced
Detected in single
null
Cancer enriched
Detected in single
9
Not detected
Not detected
null
Cell type enriched
Detected in some
10
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,609
4
ENSG00000182224
CYB5D1
Cytochrome b5 domain containing 1
[ "Q6P9G0" ]
17
7857746-7862282
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA021632" ]
[ "FLJ32499" ]
[ "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoli", "Golgi apparatus" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 17: Choroid plexus - Cilium
Cluster 42: Non-specific - Unknown function
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in many
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
14,610
4
ENSG00000182240
BACE2
Beta-secretase 2
[ "Q9Y5Z0" ]
21
41167801-41282530
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035416" ]
[ "AEPLC", "ALP56", "CEAP1", "DRAP" ]
[ "Enzymes", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[]
[ "Aspartyl protease", "Hydrolase", "Protease" ]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
null
Approved
null
16
null
null
Cluster 22: Eosinophils - Transcription
Cluster 27: Non-specific - Mixed function
Cluster 7: Liver cancer - Metabolism
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 60: Stomach - Digestion
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
6
2
2
1
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
14,611
3
ENSG00000182247
UBE2E2
Ubiquitin conjugating enzyme E2 E2
[ "Q96LR5" ]
3
23203020-23591794
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003303", "HPA028872", "HPA030445", "CAB073417" ]
[ "FLJ25157", "UbcH8" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Transferase" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Approved
null
61
No
No
Cluster 23: B-cells - Immunoglobulins
Cluster 34: Non-specific - Mixed function
Cluster 45: Non-specific - Nuclear processes
Cluster 74: Microglia - Neuroimmunity & neuroinflammation
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
6
3
0
3
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Squamous Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
14,612
3
ENSG00000182256
GABRG3
Gamma-aminobutyric acid type A receptor subunit gamma3
[ "Q99928" ]
15
26971181-27541984
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA054010" ]
[]
[ "FDA approved drug targets", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Ion transport", "Transport" ]
[ "Chloride channel", "Ion channel" ]
[ "FDA approved drug targets" ]
[ "Plasma membrane", "Microtubules" ]
[ "Nucleoli" ]
[]
[]
Approved
Approved
null
null
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 12: Bone cancer - Neuronal signaling
Cluster 109: Neurons - Neuronal signaling
Cluster 42: Retina - Visual perception
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,615
6
ENSG00000182261
NLRP10
NLR family pyrin domain containing 10
[ "Q86W26" ]
11
7957537-7965447
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA039498", "HPA040101" ]
[ "CLR11.1", "NALP10", "NOD8", "PAN5", "Pynod" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Adaptive immunity", "Immunity", "Inflammatory response", "Innate immunity" ]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Uncertain
null
1
null
null
null
Cluster 9: Non-specific - Receptor signaling
Cluster 64: Connective tissue cells - ECM organization
Cluster 64: Renal epithelial cells - Ion transport & homeostasis
Cluster 37: Skin - Keratinization
Group enriched
Detected in some
11
Low cancer specificity
Detected in single
null
Not detected
Not detected
null
Cell type enhanced
Detected in single
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,616
9
ENSG00000182263
FIGN
Fidgetin, microtubule severing factor
[ "Q5HY92" ]
2
163593396-163736012
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA034987" ]
[]
[ "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "Mitosis" ]
[]
[]
[]
[]
[]
[]
null
Approved
null
2
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 65: Non-specific - Unknown function
Cluster 61: Schwann cells & Melanocytes - Mixed function
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
33
0
0
0
[]
[]
[]
14,617
4
ENSG00000182264
IZUMO1
Izumo sperm-egg fusion 1
[ "Q8IYV9" ]
19
48740852-48746909
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038104" ]
[ "IZUMO", "MGC34799", "OBF" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Fertilization" ]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
2
null
null
null
Cluster 35: Non-specific - DNA binding
Cluster 13: Non-specific - Mixed function
Cluster 90: Elongating spermatids - Spermiogenesis: Elongation
Cluster 23: Testis - Spermatogenesis
Tissue enriched
Detected in some
11
Not detected
Not detected
null
Not detected
Not detected
null
Group enriched
Detected in some
6
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,618
9
ENSG00000182271
TMIGD1
Transmembrane and immunoglobulin domain containing 1
[ "Q6UXZ0" ]
17
30316333-30334059
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA021946" ]
[ "TMIGD", "UNQ9372" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Mitochondria", "Cytosol" ]
[]
[]
[]
Uncertain
null
null
1
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 77: Intestine - Digestion
Tissue enriched
Detected in some
29
Cancer enriched
Detected in single
7
Group enriched
Detected in some
5
Group enriched
Detected in some
26
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,619
3
ENSG00000182272
B4GALNT4
Beta-1,4-N-acetyl-galactosaminyltransferase 4
[ "Q76KP1" ]
11
369499-382117
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA043276", "HPA053126" ]
[ "FLJ25045", "NGalNAc-T1" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Transferase" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[ "Vesicles" ]
[]
[]
Uncertain
Uncertain
null
null
null
No
null
Cluster 32: Cerebral cortex - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 28: Astrocytes - Homeostasis & neuron support
Cluster 27: Cerebellum - Synaptic function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Lung Squamous Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
14,620
4
ENSG00000182287
AP1S2
Adaptor related protein complex 1 subunit sigma 2
[ "P56377" ]
X
15825806-15854931
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049894", "HPA060945" ]
[ "MRX59", "MRXS5", "PGS", "SIGMA1B" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Protein transport", "Transport" ]
[]
[ "Intellectual disability" ]
[ "Golgi apparatus", "Vesicles" ]
[]
[]
[]
Supported
Enhanced
null
14
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 49: Hindbrain - Mixed function
Cluster 69: Skin cancer - ECM organization
Cluster 10: Epididymal principal cells - Sperm maturation microenvironment
Cluster 22: Epididymis - Mixed function
Tissue enriched
Detected in all
7
Cancer enhanced
Detected in all
null
Group enriched
Detected in all
4
Cell type enriched
Detected in many
4
Group enriched
Detected in all
4
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
14,621
5
ENSG00000182307
C8orf33
Chromosome 8 open reading frame 33
[ "Q9H7E9" ]
8
145052465-145066685
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA024812", "HPA026104" ]
[ "FLJ20989" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Plasma membrane" ]
[]
[]
[]
Uncertain
Approved
null
32
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 44: Non-specific - Mixed function
Cluster 40: Non-specific - Unknown function
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 4: Adrenal gland - Steroid metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
14,622
9
ENSG00000182308
DCAF4L1
DDB1 and CUL4 associated factor 4 like 1
[ "Q3SXM0" ]
4
41981756-41986465
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "CAB073535" ]
[ "WDR21B" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[ "Nucleoli" ]
[]
[]
Supported
Enhanced
null
17
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 106: Spermatogonia - Spermatogonial differentiation
Cluster 6: Testis - Spermatogenesis
Tissue enriched
Detected in some
21
Not detected
Not detected
null
Cancer enriched
Detected in single
41
Group enriched
Detected in some
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,623
9
ENSG00000182310
SPACA6
Sperm acrosome associated 6
[ "W5XKT8" ]
19
51689128-51712387
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "LET7EH", "LINC00085", "NCRNA00085", "SPACA6P" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Fertilization" ]
[]
[]
[]
[]
[]
[]
null
null
null
1
null
null
null
Cluster 47: Endothelial cells - Vasculature
Cluster 72: Neuronal - Signal transduction
Cluster 83: Epicardial mesothelial cells - Basic cellular functions
Cluster 67: Testis - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in single
null
Low cancer specificity
Detected in single
null
Cell type enriched
Detected in many
6
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,624
5
ENSG00000182315
MBD3L3
Methyl-CpG binding domain protein 3 like 3
[ "A6NE82" ]
19
7056207-7069665
No human protein/transcript evidence
No human protein/transcript evidence
null
null
[ "HPA051259" ]
[]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Repressor" ]
[]
[ "Nucleoplasm", "Nucleoli" ]
[]
[]
[]
Uncertain
null
null
1
null
null
null
null
Cluster 12: Bone cancer - Neuronal signaling
Cluster 65: Non-specific - Cell growth & division
null
Not detected
Not detected
null
Cancer enriched
Detected in single
122
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,625
1
ENSG00000182318
ZSCAN22
Zinc finger and SCAN domain containing 22
[ "P10073" ]
19
58326994-58342332
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006471" ]
[ "HKR2", "ZNF50" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Plasma membrane", "Cytosol" ]
[ "Actin filaments" ]
[]
[]
Uncertain
Uncertain
null
31
null
null
Cluster 16: Non-specific - Cell proliferation
Cluster 34: Non-specific - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
14,626
4
ENSG00000182324
KCNJ14
Potassium inwardly rectifying channel subfamily J member 14
[ "Q9UNX9" ]
19
48455574-48466980
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "IRK4", "Kir2.4" ]
[ "FDA approved drug targets", "Predicted membrane proteins", "Voltage-gated ion channels" ]
[ "Ion transport", "Potassium transport", "Transport" ]
[ "Ion channel", "Voltage-gated channel" ]
[ "FDA approved drug targets" ]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 19: Astrocytes - Mixed function
Cluster 56: Non-specific - Sensory perception
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 46: Brain & retina - Neuronal signaling
Tissue enriched
Detected in some
12
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enriched
Detected in many
13
Immune cell enhanced
Detected in single
null
1
0
1
[]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma" ]
14,627
8
ENSG00000182325
FBXL6
F-box and leucine rich repeat protein 6
[ "Q8N531" ]
8
144355431-144359376
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA008867" ]
[ "FBL6" ]
[ "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[]
[]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Approved
null
null
49
Yes
No
Cluster 29: Non-specific - Unknown function
Cluster 12: Non-specific - Vasculature
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 104: Brain endothelial cells - Blood brain barrier
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
2
0
2
[ "Glioblastoma Multiforme" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Pancreatic Adenocarcinoma" ]
14,628
3
ENSG00000182327
GLTPD2
Glycolipid transfer protein domain containing 2
[ "A6NH11" ]
17
4788964-4790589
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA058295", "HPA065267" ]
[]
[ "Predicted secreted proteins" ]
[]
[]
[]
[ "Vesicles" ]
[ "Nucleoplasm" ]
[ "Secreted - unknown location" ]
[ "No annotated function" ]
Supported
Uncertain
null
null
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 1: Neurons - Mixed function
Cluster 18: Liver cancer - Metabolism
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 31: Liver - Metabolism & Coagulation
Tissue enriched
Detected in some
6
Cancer enhanced
Detected in many
null
Cancer enriched
Detected in many
5
Group enriched
Detected in some
6
Not detected in immune cells
Not detected
null
3
0
3
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
14,630
2
ENSG00000182329
KIAA2012
KIAA2012
[]
2
202073255-202205188
Evidence at protein level
Evidence at protein level
null
null
[ "HPA077834" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
null
Cluster 17: Choroid plexus - Cilium
Cluster 11: Neuronal - Sensory perception
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enriched
Detected in some
6
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,631
3
ENSG00000182330
PRAMEF8
PRAME family member 8
[ "Q5VWM4" ]
1
13281304-13285137
Evidence at transcript level
No human protein/transcript evidence
Evidence at transcript level
Evidence at transcript level
[ "HPA049887", "HPA051704" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
null
Cluster 34: Testis cancer - Unknown function
null
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,632
2
ENSG00000182333
LIPF
Lipase F, gastric type
[ "P07098" ]
10
88664441-88678814
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA045930" ]
[ "HGL", "HLAL" ]
[ "Enzymes", "FDA approved drug targets", "Metabolic proteins", "Predicted secreted proteins" ]
[ "Lipid degradation", "Lipid metabolism" ]
[ "Hydrolase" ]
[ "FDA approved drug targets" ]
[]
[]
[ "Secreted to digestive system" ]
[ "Enzyme" ]
null
Enhanced
null
1
null
null
null
null
Cluster 27: Breast cancer - Unknown function
Cluster 97: Non-specific - Cellular respiration
Cluster 60: Stomach - Digestion
Tissue enriched
Detected in many
143
Not detected
Not detected
null
Cancer enriched
Detected in some
59
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,633
9
ENSG00000182334
OR5P3
Olfactory receptor family 5 subfamily P member 3
[ "Q8WZ94" ]
11
7824818-7830840
Evidence at transcript level
No human protein/transcript evidence
Evidence at transcript level
Evidence at transcript level
[ "HPA060787" ]
[ "JCG1" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
null
null
null
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,634
1
ENSG00000182346
DAOA
D-amino acid oxidase activator
[ "P59103" ]
13
105465867-105491034
Evidence at protein level
No human protein/transcript evidence
Evidence at protein level
Evidence at protein level
[ "HPA053114" ]
[ "G72" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Schizophrenia" ]
[]
[]
[]
[]
null
Uncertain
null
2
null
null
null
null
null
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,635
7
ENSG00000182348
ZNF804B
Zinc finger protein 804B
[ "A4D1E1" ]
7
88759700-89338528
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA026702" ]
[ "FLJ32110" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 33: Thyroid gland - Tissue development
Tissue enriched
Detected in single
4
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,636
2
ENSG00000182359
KBTBD3
Kelch repeat and BTB domain containing 3
[ "Q8NAB2" ]
11
106051098-106077459
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA047385" ]
[ "BKLHD3" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 26: Oligodendrocytes - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase
Cluster 65: Brain - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
14,637
5
ENSG00000182362
YBEY
YbeY metalloendoribonuclease
[ "P58557" ]
21
46286342-46297751
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA016593", "HPA018162" ]
[ "C21orf57" ]
[ "Predicted intracellular proteins" ]
[]
[ "Endonuclease", "Hydrolase", "Nuclease" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Approved
null
3
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 28: Oligodendrocytes - Mixed function
Cluster 25: Non-specific - Ribosome
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 67: Testis - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
4
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
14,638
9
ENSG00000182372
CLN8
CLN8 transmembrane ER and ERGIC protein
[ "Q9UBY8" ]
8
1755778-1801711
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "C8orf61", "EPMR", "FLJ39417", "TLCD6" ]
[ "Disease related genes", "Human disease related genes", "Predicted membrane proteins" ]
[]
[]
[ "Disease variant", "Epilepsy", "Intellectual disability", "Neurodegeneration", "Neuronal ceroid lipofuscinosis" ]
[]
[]
[]
[]
null
null
null
1
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 30: White matter - Myelination
Cluster 47: Leukemia - Hemostasis
Cluster 74: Microglia - Neuroimmunity & neuroinflammation
Cluster 3: Oligodendrocytes - Myelination
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Immune cell enriched
Detected in all
5
4
0
4
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma", "Rectum Adenocarcinoma" ]
14,639
5
ENSG00000182378
PLCXD1
Phosphatidylinositol specific phospholipase C X domain containing 1
[ "Q9NUJ7" ]
X
276322-303356
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA007721" ]
[ "FLJ11323" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Approved
null
1
null
Yes
Cluster 40: Monocytes - Innate immune response
Cluster 37: Neurons - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Head and Neck Squamous Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Prostate Adenocarcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Prostate Adenocarcinoma" ]
14,640
4
ENSG00000182379
NXPH4
Neurexophilin 4
[ "O95158" ]
12
57216794-57226449
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[ "NPH4" ]
[ "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted in brain" ]
[ "No annotated function" ]
null
null
null
9
null
null
null
Cluster 43: Hindbrain - Mixed function
Cluster 12: Bone cancer - Neuronal signaling
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 2: Non-specific - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
14,641
6
ENSG00000182389
CACNB4
Calcium voltage-gated channel auxiliary subunit beta 4
[ "O00305" ]
2
151832771-152099167
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA015601" ]
[ "EJM4" ]
[ "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Calcium transport", "Ion transport", "Transport" ]
[ "Calcium channel", "Ion channel", "Voltage-gated channel" ]
[ "Disease variant", "Epilepsy", "FDA approved drug targets" ]
[]
[]
[]
[]
null
Approved
null
3
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 15: Non-specific - Transcription
Cluster 64: Connective tissue cells - ECM organization
Cluster 43: Sertoli cells - Spermatogenesis microenvironment
Cluster 27: Cerebellum - Synaptic function
Group enriched
Detected in many
6
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
5
0
0
0
[]
[]
[]
14,642
3
ENSG00000182393
IFNL1
Interferon lambda 1
[ "Q8IU54" ]
19
39296407-39298673
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "IL-29", "IL29" ]
[ "Predicted secreted proteins" ]
[ "Antiviral defense" ]
[ "Cytokine" ]
[]
[]
[]
[ "Secreted to blood" ]
[ "Interferon" ]
null
null
null
1
null
null
Cluster 1: T-cells - Unknown function
Cluster 51: Neurons - Mixed function
Cluster 71: Lymphoma - Inflammatory response
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Group enriched
Detected in some
6
Group enriched
Detected in many
10
0
0
0
[]
[]
[]
14,643
4
ENSG00000182400
TRAPPC6B
Trafficking protein particle complex subunit 6B
[ "Q86SZ2" ]
14
39147811-39170532
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA047928" ]
[]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Neurogenesis" ]
[]
[ "Disease variant", "Epilepsy", "Intellectual disability" ]
[ "Endoplasmic reticulum" ]
[]
[]
[]
Approved
Uncertain
null
24
null
null
Cluster 33: Non-specific - ATP binding
Cluster 14: Neurons - Synaptic function
Cluster 30: Non-specific - Gene expression regulation
Cluster 7: Non-specific - Transcription
Cluster 27: Cerebellum - Synaptic function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
14,644
3
ENSG00000182405
PGBD4
PiggyBac transposable element derived 4
[ "Q96DM1" ]
15
34102083-34108686
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA040896", "HPA059823" ]
[ "FLJ32638", "FLJ37497" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Centrosome" ]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 20: Non-specific - DNA binding
Cluster 37: Neurons - Mixed function
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 90: Elongating spermatids - Spermiogenesis: Elongation
Cluster 40: Non-specific - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
14,645
3
ENSG00000182415
CDY2A
Chromodomain Y-linked 2A
[ "Q9Y6F7" ]
Y
18025787-18027746
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA066682" ]
[ "CDY2" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Acyltransferase", "Transferase" ]
[]
[]
[]
[]
[]
null
Supported
null
null
null
null
null
null
null
null
Cluster 22: Epididymis - Mixed function
Group enriched
Detected in some
15
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,646
5
ENSG00000182446
NPLOC4
NPL4 homolog, ubiquitin recognition factor
[ "Q8TAT6" ]
17
81556887-81648465
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA021560", "HPA023295" ]
[ "FLJ20657", "KIAA1499", "NPL4" ]
[ "Essential proteins", "Predicted intracellular proteins", "Transporters" ]
[ "Ubl conjugation pathway" ]
[ "Chaperone" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Supported
Enhanced
null
47
null
null
Cluster 26: Monocytes - Plasma membrane proteins
Cluster 18: Non-specific - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 7: Non-specific - Transcription
Cluster 24: Non-specific - Transcription
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Immune cell enhanced
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
14,647
5
ENSG00000182447
OTOL1
Otolin 1
[ "A6NHN0" ]
3
161496808-161503942
Evidence at protein level
Evidence at transcript level
No human protein/transcript evidence
Evidence at protein level
[ "HPA041030" ]
[ "C1QTNF15", "C1QTNF16" ]
[ "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted in other tissues" ]
[ "No annotated function" ]
null
Uncertain
null
1
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 35: Neurons - Synaptic function & neurogenesis
null
Not detected
Not detected
null
Cancer enriched
Detected in single
21
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,648
3
ENSG00000182450
KCNK4
Potassium two pore domain channel subfamily K member 4
[ "Q9NYG8" ]
11
64291302-64300031
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "K2p4.1", "TRAAK" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Voltage-gated ion channels" ]
[ "Ion transport", "Potassium transport", "Transport" ]
[ "Ion channel", "Potassium channel", "Voltage-gated channel" ]
[ "Disease variant", "Epilepsy", "Intellectual disability" ]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 3: Rhabdoid - Membrane components
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 78: Brain - Neuronal signaling
Tissue enriched
Detected in single
56
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,649
8
ENSG00000182459
TEX19
Testis expressed 19
[ "Q8NA77" ]
17
82359247-82363775
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA054577" ]
[ "FLJ35767" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation", "Meiosis", "Spermatogenesis" ]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
6
null
null
null
null
Cluster 51: Myeloma - Immunoglobulins
Cluster 3: Early primary spermatocytes - Early meiosis
Cluster 23: Testis - Spermatogenesis
Tissue enriched
Detected in single
216
Cancer enhanced
Detected in many
null
Not detected
Not detected
null
Cell type enriched
Detected in some
16
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,650
2
ENSG00000182463
TSHZ2
Teashirt zinc finger homeobox 2
[ "Q9NRE2" ]
20
52972358-53495330
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA038123" ]
[ "C20orf17", "OVC10-2", "TSH2", "ZABC2", "ZNF218" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Developmental protein", "DNA-binding", "Repressor" ]
[]
[ "Golgi apparatus" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Uncertain
null
15
null
null
Cluster 31: T-cells - T-cell receptor
Cluster 22: Non-specific - Mixed function
Cluster 71: Lymphoma - Inflammatory response
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
3
2
2
[]
[ "Glioblastoma Multiforme", "Ovary Serous Cystadenocarcinoma", "Thyroid Carcinoma" ]
[ "Glioblastoma Multiforme", "Ovary Serous Cystadenocarcinoma", "Thyroid Carcinoma" ]
14,651
1
ENSG00000182472
CAPN12
Calpain 12
[ "Q6ZSI9" ]
19
38730187-38769904
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA053322" ]
[]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Protease", "Thiol protease" ]
[]
[ "Focal adhesion sites" ]
[ "Nucleoplasm" ]
[]
[]
Approved
null
null
null
null
null
Cluster 32: Basophils - Transcription
Cluster 24: Neurons - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 88: Proximal tubular cells - Transmembrane transport
Cluster 31: Liver - Metabolism & Coagulation
Group enriched
Detected in many
5
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enriched
Detected in some
10
Group enriched
Detected in many
9
3
0
3
[ "Lung Adenocarcinoma" ]
[ "Ovary Serous Cystadenocarcinoma", "Uterine Corpus Endometrial Carcinoma" ]
[ "Lung Adenocarcinoma", "Ovary Serous Cystadenocarcinoma", "Uterine Corpus Endometrial Carcinoma" ]
14,652
9
ENSG00000182473
EXOC7
Exocyst complex component 7
[ "Q9UPT5" ]
17
76081016-76121576
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA022840", "HPA022842" ]
[ "BLOM4", "EXO70", "Exo70p", "KIAA1067", "YJL085W" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Transporters" ]
[ "Exocytosis", "Protein transport", "Transport" ]
[]
[ "Epilepsy" ]
[ "Cytosol" ]
[ "Vesicles", "Plasma membrane" ]
[]
[]
Approved
Supported
null
44
null
null
Cluster 25: Non-specific - Unknown function
Cluster 24: Neurons - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 97: Non-specific - Cellular respiration
Cluster 69: Parathyroid gland - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
14,653
3
ENSG00000182477
OR2B8P
Olfactory receptor family 2 subfamily B member 8 pseudogene
[]
6
28053228-28054165
Evidence at transcript level
Evidence at transcript level
null
null
[]
[ "hs6M1-29P", "OR2B8" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 6: Leukemia - Signal transduction
null
null
Not detected
Not detected
null
Not detected
Not detected
null
null
null
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,654
4
ENSG00000182481
KPNA2
Karyopherin subunit alpha 2
[ "P52292" ]
17
68035636-68047364
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB015460", "HPA041270" ]
[ "IPOA1", "PTAC58", "QIP2", "RCH1", "SRP1alpha" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins", "Transporters" ]
[ "Host-virus interaction", "Protein transport", "Transport" ]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Enhanced
null
203
Yes
Yes
Cluster 5: Non-specific - Cell proliferation
Cluster 14: Neurons - Synaptic function
Cluster 27: Breast cancer - Unknown function
Cluster 27: Non-specific - Cell proliferation
Cluster 39: Testis - Nuclear processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
7
2
6
[ "Colon Adenocarcinoma" ]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Bladder Urothelial Carcinoma", "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
14,655
5
ENSG00000182484
WASH6P
WASP family homolog 6, pseudogene
[]
X
156020826-156025710
Evidence at transcript level
Evidence at transcript level
null
null
[ "HPA002689" ]
[ "CXYorf1", "FAM39A" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
null
Cluster 6: Non-specific - Immune response
Cluster 62: Non-specific - Plasma proteins
Cluster 58: Mast cells - Allergic inflammatory responses
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Ovary Serous Cystadenocarcinoma" ]
[]
[ "Ovary Serous Cystadenocarcinoma" ]
14,656
7
ENSG00000182489
XKRX
XK related X-linked
[ "Q6PP77" ]
X
100913445-100929433
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[]
[ "XKR2", "XPLAC" ]
[ "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
Cluster 34: B-cells - Unknown function
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 30: Non-specific - Gene expression regulation
Cluster 91: Pituicytes/FSC - Homeostasis & neuron support
Cluster 58: Skin - Keratinization
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
5
0
0
0
[]
[]
[]
14,657
5
ENSG00000182492
BGN
Biglycan
[ "P21810" ]
X
153494980-153509546
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003157", "CAB003678" ]
[ "DSPG1", "SLRR1A" ]
[ "Disease related genes", "Human disease related genes", "Predicted secreted proteins" ]
[]
[]
[ "Aortic aneurysm", "Disease variant", "Dwarfism" ]
[ "Golgi apparatus" ]
[ "Endoplasmic reticulum" ]
[ "Secreted to extracellular matrix" ]
[ "No annotated function" ]
Approved
Enhanced
null
5
null
null
null
Cluster 34: Non-specific - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 110: Mural cells - ECM organization
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enriched
Detected in many
5
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[]
[ "Colon Adenocarcinoma", "Glioblastoma Multiforme", "Skin Cutaneous Melanoma" ]
[ "Colon Adenocarcinoma", "Glioblastoma Multiforme", "Skin Cutaneous Melanoma" ]
14,658
6
ENSG00000182504
CEP97
Centrosomal protein 97
[ "Q8IW35" ]
3
101724534-101770562
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA002980" ]
[ "FLJ23047", "LRRIQ2" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Cilium biogenesis/degradation" ]
[ "Calmodulin-binding" ]
[]
[ "Centriolar satellite", "Centrosome", "Cytosol" ]
[ "Basal body" ]
[]
[]
Approved
Uncertain
null
31
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 28: Oligodendrocytes - Mixed function
Cluster 63: Non-specific - Protein processing
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 3: Oligodendrocytes - Myelination
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in single
null
2
0
2
[]
[ "Kidney Chromophobe", "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Chromophobe", "Ovary Serous Cystadenocarcinoma" ]
14,659
3
ENSG00000182508
LHFPL1
LHFPL tetraspan subfamily member 1
[ "Q86WI0" ]
X
112630648-112680054
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA003029" ]
[]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
4
null
null
Cluster 15: NK-cells - Unknown function
Cluster 19: Astrocytes - Mixed function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 28: Astrocytes - Homeostasis & neuron support
Cluster 78: Brain - Neuronal signaling
Tissue enhanced
Detected in some
null
Cancer enriched
Detected in single
5
Low cancer specificity
Detected in single
null
Cell type enriched
Detected in some
8
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,660
1
ENSG00000182511
FES
FES proto-oncogene, tyrosine kinase
[ "P07332" ]
15
90883695-90895776
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001376" ]
[ "FPS" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Kinase", "Transferase", "Tyrosine-protein kinase" ]
[ "Cancer-related genes", "Proto-oncogene", "Tumor suppressor" ]
[ "Nucleoplasm", "Cytosol" ]
[ "Vesicles" ]
[]
[]
Approved
Approved
null
11
null
null
Cluster 29: Non-specific - Unknown function
Cluster 12: Non-specific - Vasculature
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in all
null
Cancer enriched
Detected in many
5
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
4
0
4
[ "Rectum Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Glioblastoma Multiforme", "Skin Cutaneous Melanoma" ]
[ "Colon Adenocarcinoma", "Glioblastoma Multiforme", "Rectum Adenocarcinoma", "Skin Cutaneous Melanoma" ]
14,661
4
ENSG00000182512
GLRX5
Glutaredoxin 5
[ "Q86SX6" ]
14
95533503-95544724
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042465", "HPA063716" ]
[ "C14orf87", "GRX5", "PR01238" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant" ]
[ "Mitochondria" ]
[]
[]
[]
Supported
Approved
null
9
null
null
Cluster 30: Non-specific - DNA binding
Cluster 14: Neurons - Synaptic function
Cluster 30: Non-specific - Gene expression regulation
Cluster 66: Erythroid cells - Erythroid differentiation and maturation
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
14,662
3
ENSG00000182518
FAM104B
Family with sequence similarity 104 member B
[ "Q5XKR9" ]
X
55143102-55161310
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA049082" ]
[ "CXorf44", "FLJ20434" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Approved
null
null
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 28: Oligodendrocytes - Mixed function
Cluster 36: Non-specific - mRNA processing
Cluster 90: Elongating spermatids - Spermiogenesis: Elongation
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Lung Squamous Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]
14,663
8
ENSG00000182521
TBPL2
TATA-box binding protein like 2
[ "Q6SJ96" ]
14
55414210-55456726
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA056241" ]
[ "TBP2", "TRF3" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Developmental protein", "DNA-binding" ]
[]
[]
[]
[]
[]
null
Uncertain
null
3
null
null
null
Cluster 25: Non-specific - Transcription
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 41: Oocytes - Oogenesis
Cluster 61: Non-specific - Transcription
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Cancer enriched
Detected in many
4
Cell type enriched
Detected in some
12
Not detected in immune cells
Not detected
null
2
0
2
[ "Skin Cutaneous Melanoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Skin Cutaneous Melanoma" ]
14,664
7
ENSG00000182534
MXRA7
Matrix remodeling associated 7
[ "P84157" ]
17
76672551-76711004
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044819", "HPA075316" ]
[ "FLJ46603", "PS1TP1", "TMAP1" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Endoplasmic reticulum" ]
[]
[]
[]
Enhanced
Uncertain
null
5
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 44: Non-specific - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 62: Smooth muscle cells - Muscle contraction
Cluster 1: Choroid plexus - Transmembrane transport
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Lung Adenocarcinoma" ]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme", "Lung Adenocarcinoma" ]
14,666
1
ENSG00000182541
LIMK2
LIM domain kinase 2
[ "P53671" ]
22
31212239-31280080
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA008183", "CAB019313", "HPA053882" ]
[]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
15
null
Yes
Cluster 21: Neutrophils - Unknown function
Cluster 44: Non-specific - Mixed function
Cluster 71: Lymphoma - Inflammatory response
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in all
10
Group enriched
Detected in all
4
0
0
0
[]
[]
[]
14,667
9
ENSG00000182544
MFSD5
Major facilitator superfamily domain containing 5
[ "Q6N075" ]
12
53251251-53254406
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA039773" ]
[ "HsMOT2", "MGC11308", "SLC61A1" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Transport" ]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
57
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 27: Non-specific - Mixed function
Cluster 38: Non-specific - Transcription
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 81: Squamous epithelium - Keratinization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
2
2
[]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
14,668
4
ENSG00000182545
RNASE10
Ribonuclease A family member 10 (inactive)
[ "Q5GAN6" ]
14
20505537-20513884
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA052593" ]
[ "RAH1", "RNASE9" ]
[ "Predicted secreted proteins" ]
[ "Cell adhesion", "Fertilization" ]
[]
[]
[]
[]
[ "Secreted - unknown location" ]
[ "Cell adhesion" ]
null
Uncertain
null
6
null
null
null
Cluster 6: Non-specific - Immune response
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 64: Renal epithelial cells - Ion transport & homeostasis
null
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Colon Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Colon Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
14,669
2
ENSG00000182551
ADI1
Acireductone dioxygenase 1
[ "Q9BV57" ]
2
3497366-3519531
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035403", "HPA035404" ]
[ "APL1", "ARD", "FLJ10913", "HMFT1638", "MTCBP-1", "mtnD", "SIPL" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Amino-acid biosynthesis", "Methionine biosynthesis" ]
[ "Dioxygenase", "Oxidoreductase" ]
[]
[ "Nucleoplasm" ]
[ "Golgi apparatus" ]
[]
[]
Supported
Approved
null
2
null
null
Cluster 29: Non-specific - Unknown function
Cluster 21: Non-specific - Metabolism
Cluster 10: Ciliated cells - Ion channel activity
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 16: Liver & Kidney - Metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
4
Low immune cell specificity
Detected in all
null
2
0
2
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
14,670
4
ENSG00000182552
RWDD4
RWD domain containing 4
[ "Q6NW29" ]
4
183639635-183659203
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036501", "HPA036502" ]
[ "FAM28A", "MGC10198", "RWDD4A" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Intermediate filaments" ]
[]
[]
[]
Approved
Approved
null
10
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 21: Non-specific - Metabolism
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 94: Gonadal somatic cells - Mixed function
Cluster 4: Adrenal gland - Steroid metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
14,671
3
ENSG00000182557
SPNS3
Sphingolipid transporter 3 (putative)
[ "Q6ZMD2" ]
17
4433940-4488208
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA023928" ]
[ "MGC29671", "SLC63A3" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Lipid transport", "Transport" ]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
3
null
null
Cluster 29: Non-specific - Unknown function
Cluster 20: Macrophages & Microglia - Immune response
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 15: Bone marrow - Innate immune response
Tissue enriched
Detected in some
9
Cancer enriched
Detected in some
5
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
5
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
14,672
7
ENSG00000182566
CLEC4G
C-type lectin domain family 4 member G
[ "Q6UXB4" ]
19
7728957-7733906
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB003789", "HPA014044" ]
[ "LSECTIN", "UNQ431" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Host-virus interaction" ]
[ "Host cell receptor for virus entry", "Receptor" ]
[]
[]
[]
[]
[]
null
Enhanced
null
14
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 2: Cerebellar granular cells - Neuronal signaling
Cluster 45: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in many
null
Not detected
Not detected
null
Low cancer specificity
Detected in some
null
Cell type enriched
Detected in some
5
Immune cell enhanced
Detected in some
null
0
0
0
[]
[]
[]
14,673
2
ENSG00000182568
SATB1
SATB homeobox 1
[ "Q01826" ]
3
18345377-18445621
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA051769", "CAB056144", "HPA070534" ]
[]
[ "Disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Host-virus interaction", "Transcription", "Transcription regulation" ]
[ "Chromatin regulator", "DNA-binding", "Repressor" ]
[ "Disease variant", "Intellectual disability" ]
[ "Nucleoplasm" ]
[ "Nuclear bodies" ]
[]
[]
Supported
Enhanced
null
37
null
null
Cluster 24: Non-specific - Transcription
Cluster 53: Neurons - Mixed function
Cluster 21: Lymphoma - Adaptive immune response
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 80: Thymus - Adaptive immune response
Group enriched
Detected in all
4
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
2
0
2
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
14,674
6
ENSG00000182575
NXPH3
Neurexophilin 3
[ "O95157" ]
17
49575871-49583827
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA073819" ]
[ "NPH3" ]
[ "Predicted secreted proteins" ]
[]
[]
[]
[ "Vesicles" ]
[ "Mitotic spindle" ]
[ "Secreted in brain" ]
[ "No annotated function" ]
Approved
null
null
32
Yes
null
null
Cluster 37: Neurons - Mixed function
Cluster 32: Non-specific - Cell proliferation
Cluster 62: Smooth muscle cells - Muscle contraction
Cluster 74: Non-specific - Signal transduction
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,675
5
ENSG00000182578
CSF1R
Colony stimulating factor 1 receptor
[ "P07333" ]
5
150053291-150113372
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB008970", "HPA012323" ]
[ "C-FMS", "CD115", "CSFR", "FMS" ]
[ "Cancer-related genes", "CD markers", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "RAS pathway related proteins", "Transporters" ]
[ "Immunity", "Inflammatory response", "Innate immunity" ]
[ "Kinase", "Receptor", "Transferase", "Tyrosine-protein kinase" ]
[ "Cancer-related genes", "Disease variant", "FDA approved drug targets", "Neurodegeneration", "Proto-oncogene" ]
[ "Vesicles", "Plasma membrane" ]
[]
[ "Intracellular and membrane" ]
[ "Receptor" ]
Supported
Approved
null
19
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 20: Macrophages & Microglia - Immune response
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
1
0
1
[]
[ "Testicular Germ Cell Tumor" ]
[ "Testicular Germ Cell Tumor" ]
14,676
5
ENSG00000182580
EPHB3
EPH receptor B3
[ "P54753" ]
3
184561785-184582408
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA007698", "HPA008184", "CAB034350" ]
[ "ETK2", "Hek2", "Tyro6" ]
[ "Cancer-related genes", "Enzymes", "Predicted membrane proteins" ]
[ "Angiogenesis", "Neurogenesis" ]
[ "Developmental protein", "Kinase", "Receptor", "Transferase", "Tyrosine-protein kinase" ]
[ "Cancer-related genes" ]
[]
[]
[]
[]
null
Enhanced
null
5
null
null
null
Cluster 37: Neurons - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 58: Skin - Keratinization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
14,677
2
ENSG00000182583
VCX
Variable charge X-linked
[ "Q9H320" ]
X
7842262-7844143
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
[ "HPA044996", "HPA049357" ]
[ "VCX-10r", "VCX-B1", "VCX1", "VCX10R" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Supported
null
null
null
null
null
null
Cluster 51: Myeloma - Immunoglobulins
Cluster 106: Spermatogonia - Spermatogonial differentiation
Cluster 23: Testis - Spermatogenesis
Tissue enriched
Detected in single
80
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in some
6
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,678
6
ENSG00000182585
EPGN
Epithelial mitogen
[ "Q6UW88" ]
4
74308470-74316789
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA014420" ]
[ "ALGV3072", "EPG", "PRO9904" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins" ]
[]
[ "Growth factor" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[ "Vesicles" ]
[ "Secreted in other tissues" ]
[ "Growth factor" ]
Approved
null
null
1
null
null
null
Cluster 48: Non-specific - Mixed function
Cluster 7: Liver cancer - Metabolism
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 81: Squamous epithelium - Keratinization
Tissue enriched
Detected in many
5
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Bladder Urothelial Carcinoma" ]
[ "Bladder Urothelial Carcinoma" ]
14,679
2
ENSG00000182591
KRTAP11-1
Keratin associated protein 11-1
[ "Q8IUC1" ]
21
30880644-30881580
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA054008" ]
[ "KAP11.1" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
84
null
null
null
null
Cluster 65: Non-specific - Unknown function
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 9: Skin - Hair follicle development
Tissue enriched
Detected in some
39
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in single
15
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,680
3
ENSG00000182601
HS3ST4
Heparan sulfate-glucosamine 3-sulfotransferase 4
[ "Q9Y661" ]
16
25691959-26137685
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[ "3OST4" ]
[ "Enzymes", "Metabolic proteins", "Predicted membrane proteins" ]
[]
[ "Transferase" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 24: Neurons - Mixed function
Cluster 12: Bone cancer - Neuronal signaling
Cluster 74: Microglia - Neuroimmunity & neuroinflammation
Cluster 10: Brain - Synaptic signal transduction
Tissue enriched
Detected in some
5
Cancer enriched
Detected in single
27
Cancer enhanced
Detected in some
null
Group enriched
Detected in many
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,682
6
ENSG00000182606
TRAK1
Trafficking kinesin protein 1
[ "Q9UPV9" ]
3
42013802-42225890
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA005853", "HPA011367" ]
[ "KIAA1042", "MILT1", "OIP106" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant", "Epilepsy" ]
[ "Endoplasmic reticulum" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Approved
null
29
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 62: Skeletal muscle - Muscle contraction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
14,683
1
ENSG00000182612
TSPAN10
Tetraspanin 10
[]
17
81637171-81648754
Evidence at transcript level
Evidence at transcript level
null
null
[]
[ "OCSP" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 35: Non-specific - DNA binding
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 99: Retinal pigment epithelial cells - Retinol metabolism
Cluster 58: Skin - Keratinization
Tissue enhanced
Detected in single
null
Cancer enriched
Detected in many
6
Cancer enriched
Detected in many
12
Cell type enriched
Detected in many
11
Not detected in immune cells
Not detected
null
2
2
1
[ "Breast Invasive Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
14,684
4
ENSG00000182613
OR2V2
Olfactory receptor family 2 subfamily V member 2
[ "Q96R30" ]
5
181147586-181159285
Evidence at transcript level
Evidence at transcript level
No human protein/transcript evidence
Evidence at transcript level
[ "HPA049953" ]
[ "OR2V3", "OST713" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
Cluster 11: White matter - Signal transduction
Cluster 51: Myeloma - Immunoglobulins
Cluster 9: T-cells - Adaptive immunity: Regulation
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in single
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,685
8
ENSG00000182621
PLCB1
Phospholipase C beta 1
[ "Q9NQ66" ]
20
8077251-8968360
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004275", "CAB005334", "HPA034743", "HPA057910" ]
[ "KIAA0581", "PLC-I", "PLC154" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Lipid degradation", "Lipid metabolism" ]
[ "Hydrolase", "Transducer" ]
[ "Epilepsy" ]
[ "Plasma membrane" ]
[]
[]
[]
Approved
Enhanced
null
9
null
null
Cluster 33: Non-specific - ATP binding
Cluster 53: Neurons - Mixed function
Cluster 2: Mucus-secreting cells - Unknown function
Cluster 38: Secretory epithelial cells - Exocrine secretion
Cluster 73: Brain - Neuronal signaling
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
2
4
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
14,686
7
ENSG00000182628
SKA2
Spindle and kinetochore associated complex subunit 2
[ "Q8WVK7" ]
17
59109857-59155260
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA059235" ]
[ "FAM33A", "FLJ12758" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "Mitosis" ]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
14
null
null
Cluster 9: T-regs - Cell cycle regulation
Cluster 25: Non-specific - Transcription
Cluster 27: Breast cancer - Unknown function
Cluster 27: Non-specific - Cell proliferation
Cluster 3: Oligodendrocytes - Myelination
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[]
[ "Kidney Chromophobe", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
14,687
2
ENSG00000182631
RXFP3
Relaxin family peptide receptor 3
[ "Q9NSD7" ]
5
33936386-33938918
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA027833" ]
[ "GPCR135", "RLN3R1", "RXFPR3", "SALPR" ]
[ "G-protein coupled receptors", "Predicted membrane proteins", "Transporters" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Uncertain
null
1
null
null
null
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 11: Neuronal - Sensory perception
null
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,688
7
ENSG00000182634
OR10G7
Olfactory receptor family 10 subfamily G member 7
[ "Q8NGN6" ]
11
124036013-124041325
No human protein/transcript evidence
No human protein/transcript evidence
No human protein/transcript evidence
No human protein/transcript evidence
[]
[]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
null
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,689
7
ENSG00000182636
NDN
Necdin, MAGE family member
[ "Q99608" ]
15
23685400-23687305
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA074457" ]
[ "HsT16328", "PWCR" ]
[ "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Growth regulation", "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Approved
null
null
57
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 98: Neurons - Neurotransmission & signaling
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in single
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
14,690
9
ENSG00000182645
CCDC172
Coiled-coil domain containing 172
[ "P0C7W6" ]
10
116324448-116380029
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "C10orf96", "MGC35062" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
18
null
null
null
Cluster 9: Non-specific - Receptor signaling
Cluster 34: Testis cancer - Unknown function
Cluster 3: Early primary spermatocytes - Early meiosis
Cluster 47: Testis - Mixed function
Group enriched
Detected in some
8
Cancer enriched
Detected in single
8
Cancer enriched
Detected in single
6
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,691
5
ENSG00000182652
OR4Q3
Olfactory receptor family 4 subfamily Q member 3
[]
14
19743571-19749469
No human protein/transcript evidence
No human protein/transcript evidence
null
null
[ "HPA049924" ]
[ "C14orf13", "OR4Q4" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
null
Cluster 51: Myeloma - Immunoglobulins
null
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,692
7
ENSG00000182667
NTM
Neurotrimin
[ "Q9P121" ]
11
131370478-132336822
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB024875" ]
[ "CEPU-1", "HNT", "IGLON2", "NTRI" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Cell adhesion" ]
[]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "Cell adhesion" ]
null
Enhanced
null
4
null
null
Cluster 44: Plasmacytoid DCs - Plasma membrane proteins
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 64: Connective tissue cells - ECM organization
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 46: Brain & retina - Neuronal signaling
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
175
2
0
2
[]
[ "Colon Adenocarcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Colon Adenocarcinoma", "Ovary Serous Cystadenocarcinoma" ]
14,693
5
ENSG00000182670
TTC3
Tetratricopeptide repeat domain 3
[ "P53804" ]
21
37073226-37203112
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA016810", "HPA023964", "HPA036304" ]
[ "DCRR1", "RNF105", "TPRD", "TPRDI", "TPRDII", "TPRDIII" ]
[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Ubl conjugation pathway" ]
[ "Transferase" ]
[]
[ "Nucleoplasm", "Nucleoli" ]
[ "Cytosol" ]
[]
[]
Approved
Uncertain
null
11
No
No
Cluster 30: Non-specific - DNA binding
Cluster 23: Choroid plexus - Mixed function
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
14,694
1
ENSG00000182674
KCNB2
Potassium voltage-gated channel subfamily B member 2
[ "Q92953" ]
8
72537225-72938349
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA065970" ]
[ "Kv2.2" ]
[ "FDA approved drug targets", "Predicted membrane proteins", "Transporters", "Voltage-gated ion channels" ]
[ "Ion transport", "Potassium transport", "Transport" ]
[ "Ion channel", "Potassium channel", "Voltage-gated channel" ]
[ "FDA approved drug targets" ]
[ "Plasma membrane" ]
[ "Nucleoli", "Midbody" ]
[]
[]
Approved
null
null
2
Yes
null
null
Cluster 14: Neurons - Synaptic function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 46: Brain & retina - Neuronal signaling
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,695
6
ENSG00000182676
PPP1R27
Protein phosphatase 1 regulatory subunit 27
[ "Q86WC6" ]
17
81833492-81835050
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA042227", "HPA048632" ]
[ "DYSFIP1", "toonin" ]
[ "Predicted intracellular proteins" ]
[]
[ "Protein phosphatase inhibitor" ]
[]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
10
null
null
null
Cluster 16: Non-specific - Transcription
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 46: Skeletal myocytes - Muscle structure & formation
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enriched
Detected in some
26
Cancer enriched
Detected in single
218
Cancer enriched
Detected in single
11
Group enriched
Detected in some
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,696
7
ENSG00000182685
BRICD5
BRICHOS domain containing 5
[ "Q6PL45" ]
16
2209253-2210905
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA063522" ]
[ "C16orf79", "MGC21830" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Actin filaments" ]
[ "Nucleoplasm" ]
[]
[]
Approved
null
null
3
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 15: Non-specific - Transcription
Cluster 35: RS4;11 - Unknown function
Cluster 43: Sertoli cells - Spermatogenesis microenvironment
Cluster 71: Cerebellum - Nervous system development
Tissue enriched
Detected in all
4
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Glioblastoma Multiforme" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
14,697
4
ENSG00000182687
GALR2
Galanin receptor 2
[ "O43603" ]
17
76074781-76077537
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA044513" ]
[ "GALNR2" ]
[ "G-protein coupled receptors", "Plasma proteins", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
Cluster 1: Neurons - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
null
Cluster 77: Intestine - Digestion
Tissue enriched
Detected in some
5
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in single
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,698
1
ENSG00000182698
RESP18
Regulated endocrine specific protein 18
[ "Q5W5W9" ]
2
219327407-219333177
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 32: Cerebral cortex - Mixed function
null
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 78: Brain - Neuronal signaling
Tissue enriched
Detected in some
42
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,699
2
ENSG00000182700
IGIP
IgA inducing protein
[ "A6NJ69" ]
5
140125937-140129392
Evidence at transcript level
Evidence at transcript level
No human protein/transcript evidence
Evidence at transcript level
[ "HPA041877", "HPA048615" ]
[ "C5orf53", "LOC492311" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[]
[ "Vesicles" ]
[]
[ "Secreted to blood" ]
[ "No annotated function" ]
Approved
Uncertain
null
1
null
null
null
Cluster 19: Astrocytes - Mixed function
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 3: Oligodendrocytes - Myelination
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
14,700
5
ENSG00000182704
TSKU
Tsukushi, small leucine rich proteoglycan
[ "Q8WUA8" ]
11
76782251-76798153
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA008164" ]
[ "E2IG4", "LRRC54", "TSK" ]
[ "Predicted secreted proteins" ]
[ "Neurogenesis" ]
[ "Developmental protein" ]
[]
[ "Nucleoplasm" ]
[ "Nuclear bodies" ]
[ "Secreted to blood" ]
[ "Developmental protein" ]
Approved
Approved
null
null
null
null
null
Cluster 23: Choroid plexus - Mixed function
Cluster 7: Liver cancer - Metabolism
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 31: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
4
Not detected in immune cells
Not detected
null
4
0
4
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
14,701
1
ENSG00000182712
CMC4
C-X9-C motif containing 4
[ "P56277" ]
X
155061622-155071136
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA045866" ]
[ "MTCP1", "MTCP1NB", "p8", "P8MTCP1" ]
[ "Disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Proto-oncogene" ]
[ "Mitochondria" ]
[]
[]
[]
Supported
Approved
null
2
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 27: Non-specific - Mixed function
Cluster 36: Non-specific - mRNA processing
Cluster 97: Non-specific - Cellular respiration
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
14,702
6
ENSG00000182718
ANXA2
Annexin A2
[ "P07355" ]
15
60347134-60402883
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004311", "HPA046964", "HPA061798" ]
[ "ANX2", "ANX2L4", "CAL1H", "LIP2", "LPC2D" ]
[ "Cancer-related genes", "Disease related genes", "FDA approved drug targets", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins", "Transporters" ]
[ "Host-virus interaction" ]
[ "RNA-binding" ]
[ "Cancer-related genes", "FDA approved drug targets" ]
[ "Plasma membrane" ]
[ "Cytosol" ]
[ "Secreted to blood" ]
[ "Other" ]
Approved
Enhanced
null
57
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 12: Non-specific - Vasculature
Cluster 72: Neuronal - Signal transduction
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 11: Esophagus - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in all
4
5
2
4
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
14,703
3
ENSG00000182742
HOXB4
Homeobox B4
[ "P17483" ]
17
48575507-48578350
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA057432" ]
[ "HOX2", "HOX2F" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Developmental protein", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Centrosome" ]
[]
[]
Supported
Uncertain
null
1
null
null
null
Cluster 43: Hindbrain - Mixed function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,705
7
ENSG00000182747
SLC35D3
Solute carrier family 35 member D3
[ "Q5M8T2" ]
6
136922301-136925660
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA030431", "HPA067497" ]
[ "FRCL1" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Sugar transport", "Transport" ]
[]
[]
[ "Centriolar satellite" ]
[]
[]
[]
Approved
Uncertain
null
3
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 47: Platelets - Hemostasis
Cluster 78: Brain - Neuronal signaling
Tissue enriched
Detected in single
6
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
4
Group enriched
Detected in some
7
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,706
3
ENSG00000182752
PAPPA
Pappalysin 1
[ "Q13219" ]
9
116153791-116402321
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001667", "CAB016724" ]
[ "ASBABP2", "DIPLA1", "IGFBP-4ase", "PAPA", "PAPP-A", "PAPPA1" ]
[ "Cancer-related genes", "Candidate cardiovascular disease genes", "Enzymes", "Plasma proteins", "Predicted secreted proteins" ]
[]
[ "Hydrolase", "Metalloprotease", "Protease" ]
[ "Cancer-related genes" ]
[]
[]
[ "Secreted in female reproductive system" ]
[ "Enzyme" ]
null
Enhanced
null
3
null
null
null
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 5: Rhabdoid - Unknown function
Cluster 108: Fibroblasts - ECM organization
Cluster 43: Placenta - Pregnancy hormone signaling
Tissue enriched
Detected in many
8
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Glioblastoma Multiforme", "Lung Squamous Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Lung Squamous Cell Carcinoma" ]
14,708
2
ENSG00000182759
MAFA
MAF bZIP transcription factor A
[ "Q8NHW3" ]
8
143419182-143430732
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "hMafA", "RIPE3b1" ]
[ "Disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[ "Diabetes mellitus", "Disease variant" ]
[]
[]
[]
[]
null
null
null
3
null
null
null
Cluster 43: Hindbrain - Mixed function
Cluster 33: Sarcoma - Muscle contraction
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enriched
Detected in some
6
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,709
8
ENSG00000182768
NGRN
Neugrin, neurite outgrowth associated
[ "Q9NPE2" ]
15
90265659-90275778
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041367", "HPA076267" ]
[ "DSC92" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation" ]
[ "Developmental protein" ]
[]
[ "Mitochondria" ]
[ "Nucleoplasm", "Cytokinetic bridge" ]
[ "Intracellular and membrane" ]
[ "Developmental protein" ]
Supported
Supported
null
58
Yes
No
Cluster 3: Non-specific - Nuclear processes
Cluster 14: Neurons - Synaptic function
Cluster 58: Non-specific - Nuclear processes
Cluster 98: Neurons - Neurotransmission & signaling
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
14,710
6
ENSG00000182771
GRID1
Glutamate ionotropic receptor delta type subunit 1
[ "Q9ULK0" ]
10
85599552-86366795
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[ "GluD1", "KIAA1220" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Transport" ]
[ "Ion channel", "Ligand-gated ion channel", "Receptor" ]
[]
[]
[]
[]
[]
null
null
null
1
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 14: Oligodendrocyte progenitor cells - Development & myelination
Cluster 65: Brain - Transcription
Tissue enhanced
Detected in some
null
Cancer enriched
Detected in single
5
Group enriched
Detected in some
5
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
14,711
4
ENSG00000182774
RPS17
Ribosomal protein S17
[ "P08708" ]
15
82536750-82540459
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA055060" ]
[ "MGC72007", "RPS17L", "RPS17L1", "RPS17L2", "S17" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins", "Ribosomal proteins" ]
[]
[ "Ribonucleoprotein", "Ribosomal protein" ]
[ "Diamond-Blackfan anemia" ]
[ "Endoplasmic reticulum", "Cytosol" ]
[ "Nucleoli" ]
[]
[]
Approved
Approved
null
99
null
null
Cluster 18: Non-specific - Translation
Cluster 7: Non-specific - Ribosome
Cluster 25: Non-specific - Ribosome
Cluster 15: Non-specific - Protein processing
Cluster 54: Non-specific - Ribosome
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
14,712
3
ENSG00000182782
HCAR2
Hydroxycarboxylic acid receptor 2
[ "Q8TDS4" ]
12
122701293-122703357
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA028660" ]
[ "GPR109A", "HCA2", "HM74A", "NIACR1", "Puma-g", "PUMAG" ]
[ "FDA approved drug targets", "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Apoptosis" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[ "FDA approved drug targets" ]
[ "Cell Junctions" ]
[]
[]
[]
Supported
Approved
null
null
null
null
Cluster 28: Neutrophils - Unknown function
Cluster 12: Non-specific - Vasculature
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 84: Apical squamous epithelium - Cornification
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
4
Immune cell enriched
Detected in many
5
0
0
0
[]
[]
[]
14,713
1
ENSG00000182783
OR2T29
Olfactory receptor family 2 subfamily T member 29
[ "Q8NH02" ]
1
248556912-248562772
Evidence at transcript level
No human protein/transcript evidence
No human protein/transcript evidence
Evidence at transcript level
[]
[]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
Cluster 55: Lymphoma - Immune response
Cluster 88: Proximal tubular cells - Transmembrane transport
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in single
7
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
14,714
4