ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000188107
EYS
Eyes shut homolog
[ "Q5T1H1" ]
6
63719980-65707226
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA027103" ]
[ "bA166P24.2", "bA307F22.3", "bA74E24.1", "C6orf178", "C6orf179", "C6orf180", "dJ1018A4.2", "dJ303F19.1", "EGFL10", "EGFL11", "RP25", "SPAM" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Sensory transduction", "Vision" ]
[]
[ "Disease variant", "Retinitis pigmentosa" ]
[ "Plasma membrane", "Cytosol", "Flagellar centriole" ]
[]
[ "Secreted in other tissues" ]
[ "Other" ]
Uncertain
null
null
null
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 37: Neurons - Mixed function
Cluster 1: Neuronal - Visual perception
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 42: Retina - Visual perception
Tissue enriched
Detected in single
37
Cancer enhanced
Detected in some
null
Not detected
Not detected
null
Group enriched
Detected in many
12
Immune cell enhanced
Detected in single
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
15,816
2
ENSG00000188112
C6orf132
Chromosome 6 open reading frame 132
[ "Q5T0Z8" ]
6
42092233-42142620
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044588" ]
[ "bA7K24.2" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Golgi apparatus", "Cytosol" ]
[]
[]
[]
Approved
Enhanced
null
1
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 28: Non-specific - Nuclear processes
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enriched
Detected in many
4
Not detected in immune cells
Not detected
null
1
0
1
[ "Rectum Adenocarcinoma" ]
[]
[ "Rectum Adenocarcinoma" ]
15,817
6
ENSG00000188124
OR2AG2
Olfactory receptor family 2 subfamily AG member 2
[ "A6NM03" ]
11
6765626-6771976
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[]
[ "OR2AG2P" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 32: Cerebral cortex - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 35: Neurons - Synaptic function & neurogenesis
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,819
4
ENSG00000188130
MAPK12
Mitogen-activated protein kinase 12
[ "P53778" ]
22
50245450-50261716
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB025483", "HPA054562" ]
[ "ERK6", "p38gamma", "PRKM12", "SAPK-3", "SAPK3" ]
[ "Disease related genes", "Enzymes", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Cell cycle", "Stress response", "Transcription", "Transcription regulation" ]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Nuclear speckles" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
19
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 30: Epididymal principal cells - Sperm storage microenvironment
Cluster 19: Skeletal muscle - Striated muscle contraction
Group enriched
Detected in all
7
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,820
4
ENSG00000188133
TMEM215
Transmembrane protein 215
[ "Q68D42" ]
9
32783540-32789201
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA063207" ]
[]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Vesicles" ]
[]
[]
[]
Approved
null
null
null
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 12: Bone cancer - Neuronal signaling
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 42: Retina - Visual perception
Tissue enriched
Detected in some
7
Not detected
Not detected
null
Cancer enriched
Detected in single
17
Group enriched
Detected in some
15
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,821
3
ENSG00000188152
NUTM2G
NUT family member 2G
[ "Q5VZR2" ]
9
96928310-96940253
Evidence at protein level
Evidence at protein level
No human protein/transcript evidence
Evidence at transcript level
[ "HPA064635" ]
[ "FAM22G" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nuclear bodies" ]
[]
[]
[]
Approved
null
null
null
null
null
Cluster 22: Eosinophils - Transcription
Cluster 6: Non-specific - Immune response
Cluster 56: Non-specific - Sensory perception
Cluster 83: Epicardial mesothelial cells - Basic cellular functions
Cluster 47: Testis - Mixed function
Tissue enhanced
Detected in single
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in single
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,822
7
ENSG00000188155
KRTAP10-6
Keratin associated protein 10-6
[ "P60371" ]
21
44591268-44592505
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "KAP10.6", "KAP18.6", "KRTAP18-6", "KRTAP18.6" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
65
null
null
null
null
null
null
Cluster 9: Skin - Hair follicle development
Tissue enriched
Detected in single
11
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,824
8
ENSG00000188157
AGRN
Agrin
[ "O00468" ]
1
1020120-1056118
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA040090" ]
[ "AGRIN" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted secreted proteins", "Transporters" ]
[ "Differentiation" ]
[ "Developmental protein" ]
[ "Congenital myasthenic syndrome", "Disease variant" ]
[ "Cytosol" ]
[ "Plasma membrane" ]
[ "Secreted to extracellular matrix" ]
[ "Developmental protein" ]
Approved
Approved
null
14
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 64: Renal epithelial cells - Ion transport & homeostasis
Cluster 72: Kidney - Transmembrane transport
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
15,825
1
ENSG00000188158
NHS
NHS actin remodeling regulator
[ "Q6T4R5" ]
X
17375200-17735994
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA031497", "HPA076257" ]
[]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[ "Cataract" ]
[ "Cell Junctions" ]
[]
[]
[]
Supported
Uncertain
null
4
null
null
null
Cluster 1: Neurons - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 88: Proximal tubular cells - Transmembrane transport
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
1
0
1
[ "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Papillary Cell Carcinoma" ]
15,826
1
ENSG00000188167
TMPPE
Transmembrane protein with metallophosphoesterase domain
[ "Q6ZT21" ]
3
33090421-33097146
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA027019" ]
[ "FLJ45032" ]
[ "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Hydrolase" ]
[]
[ "Nucleoplasm", "Mitochondria" ]
[]
[]
[]
Approved
Approved
null
30
Yes
No
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 23: Choroid plexus - Mixed function
Cluster 34: Testis cancer - Unknown function
Cluster 68: Foveolar cells - Mucosal defense
Cluster 40: Non-specific - Mixed function
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Not detected
Not detected
null
Immune cell enhanced
Detected in some
null
0
0
0
[]
[]
[]
15,829
6
ENSG00000188171
ZNF626
Zinc finger protein 626
[ "Q68DY1" ]
19
20619939-20661596
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA045631" ]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nuclear membrane", "Vesicles" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 24: Non-specific - Transcription
Cluster 31: Non-specific - Transcription
Cluster 4: Non-specific - Transcription
Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func.
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
15,830
3
ENSG00000188175
HEPACAM2
HEPACAM family member 2
[ "A8MVW5" ]
7
93188534-93226469
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA012381" ]
[ "FLJ38683" ]
[ "Predicted membrane proteins" ]
[ "Cell cycle", "Cell division", "Mitosis" ]
[]
[]
[ "Vesicles", "Mitotic spindle" ]
[ "Nucleoplasm" ]
[]
[]
Supported
null
null
null
Yes
null
null
null
Cluster 10: Ciliated cells - Ion channel activity
Cluster 70: Intestinal goblet cells - Mucin production
Cluster 77: Intestine - Digestion
Tissue enriched
Detected in some
6
Group enriched
Detected in some
4
Cancer enriched
Detected in many
10
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Colon Adenocarcinoma" ]
[]
[ "Colon Adenocarcinoma" ]
15,831
8
ENSG00000188176
SMTNL2
Smoothelin like 2
[ "Q2TAL5" ]
17
4583999-4608319
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA025706" ]
[ "FLJ42461" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Nuclear speckles" ]
[]
[]
[]
Approved
null
null
null
null
null
null
Cluster 29: Forebrain - Mixed function
Cluster 34: Testis cancer - Unknown function
Cluster 36: Skeletal myocytes - Muscle excitation & contraction
Cluster 19: Skeletal muscle - Striated muscle contraction
Group enriched
Detected in many
8
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
5
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
4
2
3
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
15,832
9
ENSG00000188177
ZC3H6
Zinc finger CCCH-type containing 6
[ "P61129" ]
2
112275597-112340063
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036019", "HPA036020", "HPA076065" ]
[ "FLJ41410", "FLJ45877", "KIAA2035", "ZC3HDC6" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[]
[]
[]
[ "Nucleoplasm", "Golgi apparatus" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 24: Non-specific - Transcription
Cluster 34: Non-specific - Mixed function
Cluster 13: Non-specific - Mixed function
Cluster 7: Non-specific - Transcription
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma" ]
15,833
6
ENSG00000188186
LAMTOR4
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
[ "Q0VGL1" ]
7
100148912-100155944
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA020998" ]
[ "C7orf59" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Lysosomes" ]
[ "Golgi apparatus" ]
[]
[]
Supported
Enhanced
null
35
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 27: Non-specific - Mixed function
Cluster 39: Non-specific - Transcription
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 2: Non-specific - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
1
0
1
[]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe" ]
15,834
3
ENSG00000188191
PRKAR1B
Protein kinase cAMP-dependent type I regulatory subunit beta
[ "P31321" ]
7
549197-727650
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA026719" ]
[]
[ "Disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant", "Intellectual disability" ]
[]
[]
[]
[]
null
Approved
null
83
null
null
Cluster 39: T-cells - T-cell receptor
Cluster 1: Neurons - Mixed function
Cluster 67: Non-specific - Unknown function
Cluster 47: Platelets - Hemostasis
Cluster 10: Brain - Synaptic signal transduction
Tissue enriched
Detected in all
10
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Lung Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Lung Adenocarcinoma" ]
15,835
6
ENSG00000188199
NUTM2B
NUT family member 2B
[ "A6NNL0" ]
10
79703227-79714681
Evidence at protein level
Evidence at protein level
No human protein/transcript evidence
Evidence at transcript level
[ "HPA064635" ]
[ "bA119F19.1", "FAM22B" ]
[ "Cancer-related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Cancer-related genes" ]
[ "Nuclear bodies" ]
[]
[]
[]
Approved
null
null
null
null
null
null
Cluster 4: Non-specific - mRNA splicing & Cell cycle
Cluster 56: Non-specific - Sensory perception
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 67: Testis - Mixed function
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,836
9
ENSG00000188211
NCR3LG1
Natural killer cell cytotoxicity receptor 3 ligand 1
[ "Q68D85" ]
11
17351800-17377341
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA024137" ]
[ "B7-H6", "DKFZp686O24166" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
19
null
null
null
Cluster 5: Non-specific - Mixed function
Cluster 7: Liver cancer - Metabolism
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 77: Intestine - Digestion
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
15,837
1
ENSG00000188215
DCUN1D3
Defective in cullin neddylation 1 domain containing 3
[ "Q8IWE4" ]
16
20854925-20900358
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041983", "HPA043511" ]
[ "DKFZp686O0290", "FLJ41725", "MGC48972", "SCCRO3" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Supported
Approved
null
15
null
null
Cluster 41: Basophils - Unknown function
Cluster 55: Non-specific - Transcription
Cluster 44: Connective tissue cells - ECM organization
Cluster 103: Non-specific - Basic cellular processes
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in single
null
0
0
0
[]
[]
[]
15,838
7
ENSG00000188219
POTEE
POTE ankyrin domain family member E
[ "Q6S8J3" ]
2
131209536-131265278
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA041264", "HPA041271", "HPA043260" ]
[ "A26C1", "A26C1A", "CT104.2", "POTE-2", "POTE2", "POTE2gamma" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
17
null
null
null
Cluster 46: Brainstem - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 34: Ciliated cells - Cilia assembly & function
null
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Not detected
Not detected
null
Group enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,839
3
ENSG00000188227
ZNF793
Zinc finger protein 793
[ "Q6ZN11" ]
19
37506939-37548762
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA034781" ]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Nucleoli", "Cytosol" ]
[]
[]
Approved
Uncertain
null
1
null
null
Cluster 32: Basophils - Transcription
Cluster 15: Non-specific - Transcription
Cluster 4: Non-specific - Transcription
Cluster 43: Sertoli cells - Spermatogenesis microenvironment
Cluster 46: Brain & retina - Neuronal signaling
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
15,840
3
ENSG00000188229
TUBB4B
Tubulin beta 4B class IVb
[ "P68371" ]
9
137241287-137243707
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB010880", "HPA043640", "HPA046280" ]
[ "Beta2", "TUBB2C" ]
[ "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[ "Deafness", "Disease variant", "FDA approved drug targets", "Leber congenital amaurosis" ]
[ "Microtubules" ]
[ "Cytokinetic bridge", "Mitotic spindle", "Primary cilium", "Primary cilium tip", "Basal body", "Flagellar centriole", "Principal piece", "End piece" ]
[]
[]
Approved
Enhanced
null
173
Yes
Yes
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 44: Non-specific - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 20: Non-specific - Transcription regulation
Cluster 56: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Thyroid Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Thyroid Carcinoma" ]
15,841
2
ENSG00000188234
AGAP4
ArfGAP with GTPase domain, ankyrin repeat and PH domain 4
[ "Q96P64" ]
10
45825594-45853875
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA042490" ]
[ "AGAP8", "CTGLF1", "CTGLF5", "Em:AC012044.1", "MRIP2" ]
[ "Predicted intracellular proteins" ]
[]
[ "GTPase activation" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 4: Non-specific - mRNA splicing & Cell cycle
Cluster 56: Non-specific - Sensory perception
Cluster 105: Non-specific - Mixed function
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
2
0
2
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
15,842
9
ENSG00000188243
COMMD6
COMM domain containing 6
[ "Q7Z4G1" ]
13
75525214-75549439
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "Acrg" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation", "Ubl conjugation pathway" ]
[]
[]
[]
[]
[]
[]
null
null
null
66
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 21: Non-specific - Metabolism
Cluster 19: Non-specific - Unknown function
Cluster 15: Non-specific - Protein processing
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
15,843
1
ENSG00000188257
PLA2G2A
Phospholipase A2 group IIA
[ "P14555" ]
1
19975431-19980416
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA015236" ]
[ "PLA2B", "PLA2L" ]
[ "Enzymes", "FDA approved drug targets", "Metabolic proteins", "Predicted intracellular proteins", "Predicted secreted proteins", "RAS pathway related proteins" ]
[ "Inflammatory response", "Lipid metabolism", "Phospholipid metabolism" ]
[ "Antimicrobial", "Bacteriolytic enzyme", "Hydrolase" ]
[ "FDA approved drug targets" ]
[]
[]
[ "Secreted to blood" ]
[ "Enzyme" ]
null
Enhanced
null
1
null
null
null
Cluster 12: Non-specific - Vasculature
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 108: Fibroblasts - ECM organization
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enriched
Detected in many
5
Not detected in immune cells
Not detected
null
5
0
5
[ "Breast Invasive Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Rectum Adenocarcinoma" ]
15,844
9
ENSG00000188263
IL17REL
Interleukin 17 receptor E like
[]
22
49991811-50012765
Evidence at protein level
Evidence at protein level
null
null
[ "HPA045546" ]
[ "FLJ41993" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Supported
null
null
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 7: Liver cancer - Metabolism
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 51: Lymphoid tissue - Adaptive immune response
Group enriched
Detected in some
4
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,845
5
ENSG00000188266
HYKK
Hydroxylysine kinase
[ "A2RU49" ]
15
78507564-78537372
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA040706" ]
[ "AGPHD1", "LOC123688" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Kinase", "Transferase" ]
[]
[ "Nucleoplasm", "Vesicles", "Aggresome", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
2
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 33: Neurons - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 72: Kidney - Transmembrane transport
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
1
0
1
[ "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Papillary Cell Carcinoma" ]
15,846
4
ENSG00000188269
OR7A5
Olfactory receptor family 7 subfamily A member 5
[ "Q15622" ]
19
14826241-14835185
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA053823" ]
[ "HTPCR2" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
Cluster 26: Oligodendrocytes - Mixed function
Cluster 9: Skin cancer - Melanin biosynthesis
null
Cluster 73: Brain - Neuronal signaling
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Cancer enhanced
Detected in single
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,847
7
ENSG00000188277
C15orf62
Chromosome 15 open reading frame 62
[ "A8K5M9" ]
15
40769980-40772449
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA044636" ]
[ "LOC643338" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Approved
null
null
null
null
null
Cluster 15: Non-specific - Transcription
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 84: Apical squamous epithelium - Cornification
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enriched
Detected in some
22
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,848
4
ENSG00000188282
RUFY4
RUN and FYVE domain containing 4
[ "Q6ZNE9" ]
2
218034960-218090584
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA037980" ]
[ "FLJ46536", "ZFYVE31" ]
[ "Predicted intracellular proteins" ]
[ "Autophagy" ]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
21
null
null
null
Cluster 29: Forebrain - Mixed function
Cluster 55: Lymphoma - Immune response
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,849
3
ENSG00000188283
ZNF383
Zinc finger protein 383
[ "Q8NA42" ]
19
37217926-37248740
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA063945" ]
[ "FLJ35863", "Zfp383" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm", "Nuclear membrane" ]
[]
[]
[]
Supported
Approved
null
5
No
No
Cluster 24: Non-specific - Transcription
Cluster 38: Sub-cortical - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 55: Myocytes - Oxidative muscle function
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Skin Cutaneous Melanoma" ]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma", "Skin Cutaneous Melanoma" ]
15,850
9
ENSG00000188290
HES4
Hes family bHLH transcription factor 4
[ "Q9HCC6" ]
1
998962-1000172
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA062465" ]
[ "bHLHb42" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Differentiation", "Neurogenesis", "Transcription", "Transcription regulation" ]
[ "Developmental protein", "DNA-binding", "Repressor" ]
[]
[ "Nucleoplasm" ]
[ "Vesicles", "Cytosol" ]
[]
[]
Approved
null
null
6
null
null
Cluster 19: Eosinophils - Unknown function
Cluster 27: Non-specific - Mixed function
Cluster 59: Leukemia - T-cell receptor
Cluster 103: Non-specific - Basic cellular processes
Cluster 74: Non-specific - Signal transduction
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in some
10
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
15,851
1
ENSG00000188293
IGFL1
IGF like family member 1
[ "Q6UW32" ]
19
46229742-46231243
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA014001" ]
[ "UNQ644" ]
[ "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted in other tissues" ]
[ "No annotated function" ]
null
Uncertain
null
2
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Lung Squamous Cell Carcinoma" ]
[ "Lung Squamous Cell Carcinoma" ]
15,852
8
ENSG00000188305
PEAK3
PEAK family member 3
[ "Q6ZS72" ]
19
2274631-2282175
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA057806" ]
[ "C19orf35", "FLJ45778" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Uncertain
Uncertain
null
6
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 20: Macrophages & Microglia - Immune response
Cluster 49: HMC-1 - Innate immune response
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in some
null
Cancer enriched
Detected in single
5
Low cancer specificity
Detected in single
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
0
0
0
[]
[]
[]
15,854
2
ENSG00000188306
LRRIQ4
Leucine rich repeats and IQ motif containing 4
[ "A6NIV6" ]
3
169812870-169837773
Evidence at protein level
Evidence at protein level
No human protein/transcript evidence
Evidence at protein level
[ "HPA036271", "HPA036706" ]
[ "LRRC64" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Mitochondria" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
null
Cluster 32: Cerebral cortex - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 21: Testis - Mixed function
Tissue enriched
Detected in single
6
Cancer enhanced
Detected in single
null
Low cancer specificity
Detected in single
null
Group enriched
Detected in some
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,855
6
ENSG00000188312
CENPP
Centromere protein P
[ "Q6IPU0" ]
9
92325953-92620529
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA021787", "HPA058945" ]
[ "CENP-P", "RP11-19J3.3" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Nucleoli" ]
[]
[]
Supported
Uncertain
null
31
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 35: Non-specific - DNA binding
Cluster 43: Non-specific - Basic cellular processes
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 37: Skin - Keratinization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
5
0
5
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma", "Skin Cutaneous Melanoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Glioblastoma Multiforme", "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Skin Cutaneous Melanoma" ]
15,856
3
ENSG00000188313
PLSCR1
Phospholipid scramblase 1
[ "O15162" ]
3
146515180-146544856
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA068923", "CAB070421" ]
[ "MMTRA1B" ]
[ "Predicted intracellular proteins", "Transporters" ]
[ "Antiviral defense", "Host-virus interaction", "Lipid transport", "Transport" ]
[ "DNA-binding", "Host cell receptor for virus entry", "Hydrolase", "Nuclease", "Receptor" ]
[]
[ "Nucleoplasm", "Golgi apparatus", "Plasma membrane" ]
[]
[]
[]
Supported
Approved
null
81
null
Yes
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 43: Hindbrain - Mixed function
Cluster 31: Non-specific - Antiviral immune response
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
15,857
2
ENSG00000188316
ENO4
Enolase 4
[ "A6NNW6" ]
10
116849499-116911788
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA037938" ]
[ "AC023283.3", "C10orf134" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Glycolysis" ]
[ "Lyase" ]
[]
[ "Vesicles" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
null
null
null
null
Cluster 11: White matter - Signal transduction
Cluster 12: Bone cancer - Neuronal signaling
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Cancer enhanced
Detected in single
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
15,859
4
ENSG00000188321
ZNF559
Zinc finger protein 559
[ "Q9BR84" ]
19
9323772-9351162
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA059632", "HPA065485" ]
[ "MGC13105" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
15
null
null
Cluster 24: Non-specific - Transcription
Cluster 25: Non-specific - Transcription
Cluster 4: Non-specific - Transcription
Cluster 22: Non-specific - Basic cellular functions
Cluster 21: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in some
10
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Skin Cutaneous Melanoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Skin Cutaneous Melanoma" ]
15,860
1
ENSG00000188322
SBK1
SH3 domain binding kinase 1
[ "Q52WX2" ]
16
28259246-28323849
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[ "Sbk" ]
[ "Enzymes", "Predicted membrane proteins" ]
[]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
Cluster 1: T-cells - Unknown function
Cluster 15: Non-specific - Transcription
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 36: Skeletal myocytes - Muscle excitation & contraction
Cluster 19: Skeletal muscle - Striated muscle contraction
Group enriched
Detected in many
4
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enriched
Detected in many
4
Immune cell enhanced
Detected in some
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
15,861
7
ENSG00000188324
OR6C6
Olfactory receptor family 6 subfamily C member 6
[ "A6NF89" ]
12
55293988-55296569
Evidence at protein level
Evidence at transcript level
No human protein/transcript evidence
No human protein/transcript evidence
[ "HPA051090" ]
[]
[ "Essential proteins", "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[ "Lipid droplets", "Plasma membrane" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
null
Cluster 48: Non-specific - Mixed function
null
Cluster 103: Non-specific - Basic cellular processes
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,862
6
ENSG00000188334
BSPH1
Binder of sperm protein homolog 1
[ "Q075Z2" ]
19
47968046-47992170
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA048335" ]
[ "BSP1", "ELSPBP2" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Fertilization" ]
[]
[]
[]
[]
[ "Secreted in male reproductive system" ]
[ "Other" ]
null
Enhanced
null
null
null
null
null
Cluster 2: Neurons - Nucleosome
Cluster 38: Non-specific - Transcription
Cluster 30: Epididymal principal cells - Sperm storage microenvironment
Cluster 50: Epididymis - Male reproductive secretion
Tissue enriched
Detected in some
52
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
16
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,863
7
ENSG00000188338
SLC38A3
Solute carrier family 38 member 3
[ "Q99624" ]
3
50205246-50221486
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA031871" ]
[ "G17", "SN1" ]
[ "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Amino-acid transport", "Antiport", "Ion transport", "Sodium transport", "Symport", "Transport" ]
[]
[ "Disease variant", "Epilepsy", "FDA approved drug targets", "Intellectual disability" ]
[ "Cytosol" ]
[ "Microtubules" ]
[]
[]
Approved
null
null
null
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 19: Astrocytes - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 45: Liver - Metabolism & Coagulation
Group enriched
Detected in many
7
Cancer enhanced
Detected in many
null
Cancer enriched
Detected in many
7
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in single
null
3
0
3
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
15,864
8
ENSG00000188340
OR6N2
Olfactory receptor family 6 subfamily N member 2
[ "Q8NGY6" ]
1
158774222-158781204
Evidence at transcript level
Evidence at transcript level
No human protein/transcript evidence
Evidence at transcript level
[ "HPA056637" ]
[]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
null
null
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 15: Bone marrow - Innate immune response
Tissue enriched
Detected in single
11
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in single
8
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,865
6
ENSG00000188342
GTF2F2
General transcription factor IIF subunit 2
[ "P13984" ]
13
45120510-45284893
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006912" ]
[ "BTF4", "RAP30", "TFIIF" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Microtubules" ]
[]
[]
Supported
Supported
null
38
null
null
Cluster 22: Eosinophils - Transcription
Cluster 21: Non-specific - Metabolism
Cluster 19: Non-specific - Unknown function
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
6
0
6
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma", "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
15,866
2
ENSG00000188368
PRR19
Proline rich 19
[ "A6NJB7" ]
19
42302098-42310814
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA070350" ]
[ "MGC70924" ]
[ "Predicted intracellular proteins" ]
[ "Meiosis" ]
[]
[]
[ "Nucleoli", "Nucleoli rim", "Mitotic chromosome" ]
[ "Nucleoplasm", "Nuclear bodies", "Mitochondria" ]
[]
[]
Approved
null
null
2
Yes
No
Cluster 43: Non-specific - Transcription & Translation
Cluster 37: Neurons - Mixed function
Cluster 71: Lymphoma - Inflammatory response
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 67: Testis - Mixed function
Tissue enriched
Detected in some
5
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
2
0
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
15,869
7
ENSG00000188372
ZP3
Zona pellucida glycoprotein 3
[ "P21754" ]
7
76397518-76442071
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA054061", "HPA071198" ]
[ "ZP3-372", "ZP3-424", "ZP3A", "ZP3B", "ZPC" ]
[ "Disease related genes", "Human disease related genes", "Predicted membrane proteins", "Predicted secreted proteins" ]
[ "Fertilization" ]
[ "Receptor" ]
[ "Disease variant" ]
[]
[]
[ "Secreted in female reproductive system" ]
[ "Receptor" ]
null
Supported
null
4
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 33: Neurons - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 41: Oocytes - Oogenesis
Cluster 75: Ovary - Mixed function
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
30
Low immune cell specificity
Detected in many
null
3
2
2
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
15,870
3
ENSG00000188373
GPR15LG
G protein-coupled receptor 15 ligand
[ "Q6UWK7" ]
10
84173801-84185294
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA050920" ]
[ "AP-57", "C10orf99", "CSBF", "FLJ21763", "GPR15L", "RLLV1833", "UNQ1833" ]
[ "Predicted secreted proteins" ]
[ "Chemotaxis" ]
[ "Antibiotic", "Antimicrobial", "Cytokine" ]
[ "Tumor suppressor" ]
[]
[]
[ "Secreted in other tissues" ]
[ "Cytokine" ]
null
Enhanced
null
null
null
null
null
null
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 11: Esophagus - Basic cellular processes
Group enriched
Detected in some
4
Group enriched
Detected in some
6
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
15,871
7
ENSG00000188375
H3-5
H3.5 histone
[ "Q6NXT2" ]
12
31791185-31792298
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042570", "HPA050968", "HPA064058" ]
[ "H3.3C", "H3.5", "H3F3C" ]
[ "Predicted intracellular proteins" ]
[]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
null
24
null
null
Cluster 21: Neutrophils - Unknown function
null
Cluster 61: BICR 18 - Protein kinases
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 57: Testis - Spermatogenesis
Tissue enriched
Detected in some
7
Low cancer specificity
Detected in single
null
Cancer enhanced
Detected in single
null
Group enriched
Detected in some
11
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
15,872
2
ENSG00000188379
IFNA2
Interferon alpha 2
[ "P01563" ]
9
21384255-21385398
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA047557" ]
[ "IFN-alphaA", "IFNA" ]
[ "Predicted secreted proteins" ]
[ "Antiviral defense" ]
[ "Cytokine" ]
[]
[]
[]
[ "Secreted to blood" ]
[ "Interferon" ]
null
Uncertain
null
4
null
null
null
Cluster 11: White matter - Signal transduction
Cluster 55: Lymphoma - Immune response
Cluster 80: Oligodendrocytes - Myelination
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in single
10
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,873
5
ENSG00000188385
JAKMIP3
Janus kinase and microtubule interacting protein 3
[ "Q5VZ66" ]
10
132036336-132184858
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA022872" ]
[ "bA140A10.5", "C10orf14", "C10orf39", "FLJ37857", "KIAA4091", "NECC2" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
Cluster 26: Oligodendrocytes - Mixed function
Cluster 7: Liver cancer - Metabolism
Cluster 109: Neurons - Neuronal signaling
Cluster 3: Oligodendrocytes - Myelination
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Cancer enhanced
Detected in single
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,874
2
ENSG00000188386
PPP3R2
Protein phosphatase 3 regulatory subunit B, beta
[ "Q96LZ3" ]
9
101591604-101595021
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA047157" ]
[ "PPP3RL" ]
[ "FDA approved drug targets", "Predicted intracellular proteins" ]
[]
[]
[ "FDA approved drug targets" ]
[ "Plasma membrane" ]
[ "Primary cilium", "Cytosol" ]
[]
[]
Approved
Uncertain
null
7
null
null
null
Cluster 24: Neurons - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 6: Testis - Spermatogenesis
Tissue enriched
Detected in single
619
Not detected
Not detected
null
Not detected
Not detected
null
Group enriched
Detected in some
8
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,875
8
ENSG00000188389
PDCD1
Programmed cell death 1
[ "Q15116" ]
2
241849884-241858894
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035981", "CAB038418", "CAB076386" ]
[ "CD279", "hSLE1", "PD-1", "PD1", "SLEB2" ]
[ "CD markers", "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Adaptive immunity", "Apoptosis", "Immunity" ]
[]
[ "FDA approved drug targets" ]
[]
[]
[]
[]
null
Enhanced
null
11
null
null
Cluster 9: T-regs - Cell cycle regulation
Cluster 19: Astrocytes - Mixed function
Cluster 70: DU4475 - Unknown function
Cluster 102: Non-specific - Mixed function
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enriched
Detected in single
8
Group enriched
Detected in many
5
1
0
1
[ "Head and Neck Squamous Cell Carcinoma" ]
[]
[ "Head and Neck Squamous Cell Carcinoma" ]
15,876
4
ENSG00000188393
CLEC2A
C-type lectin domain family 2 member A
[ "Q6UVW9" ]
12
9898673-9932370
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA048530", "HPA072407" ]
[ "INPE5792", "KACL", "PILAR", "UNQ5792" ]
[ "Predicted membrane proteins" ]
[]
[ "Receptor" ]
[]
[ "Plasma membrane" ]
[]
[]
[]
Uncertain
Approved
null
5
null
null
null
Cluster 25: Non-specific - Transcription
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 26: Keratinocytes - Keratinization
Cluster 37: Skin - Keratinization
Tissue enriched
Detected in some
16
Cancer enriched
Detected in single
16
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
7
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,877
7
ENSG00000188394
GPR21
G protein-coupled receptor 21
[ "Q99679" ]
9
123033667-123035665
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA041651" ]
[]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 14: Myeloid leukemia - Innate immune response
null
Cluster 74: Non-specific - Signal transduction
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,878
7
ENSG00000188396
DYNLT4
Dynein light chain Tctex-type 4
[ "Q5JR98" ]
1
44805893-44807351
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA050116", "HPA062652" ]
[ "TCTEX1D4" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Supported
Enhanced
null
8
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 8: Immune cells - Immune response
Cluster 56: Non-specific - Sensory perception
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 1: Choroid plexus - Transmembrane transport
Group enriched
Detected in many
5
Low cancer specificity
Detected in some
null
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
8
Immune cell enriched
Detected in single
12
0
0
0
[]
[]
[]
15,879
7
ENSG00000188403
IGHV1OR15-9
Immunoglobulin heavy variable 1/OR15-9 (non-functional)
[]
15
19964666-19965101
Evidence at transcript level
Evidence at transcript level
null
null
[]
[ "IGHV1/OR15-9", "IGHV1OR159", "VSIG7" ]
[ "Immunoglobulin genes", "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
null
null
Cluster 34: Lymphoid tissue - Adaptive immune response
Group enriched
Detected in some
13
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,880
3
ENSG00000188404
SELL
Selectin L
[ "P14151" ]
1
169690665-169711702
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002144", "HPA051972" ]
[ "CD62L", "hLHRc", "LAM-1", "LAM1", "Leu-8", "LNHR", "LSEL", "Lyam-1", "LYAM1", "PLNHR" ]
[ "Cancer-related genes", "Candidate cardiovascular disease genes", "CD markers", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Cell adhesion" ]
[]
[ "Cancer-related genes" ]
[ "Cytosol" ]
[]
[]
[]
Uncertain
Enhanced
null
1
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 28: Oligodendrocytes - Mixed function
Cluster 55: Lymphoma - Immune response
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 18: Lymphoid tissue - Immune response
Group enriched
Detected in many
5
Group enriched
Detected in many
6
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
4
Low immune cell specificity
Detected in all
null
4
0
4
[ "Breast Invasive Carcinoma", "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
15,881
3
ENSG00000188408
MAGEB5
MAGE family member B5
[ "Q9BZ81" ]
X
26216169-26218270
Evidence at protein level
No human protein/transcript evidence
Evidence at transcript level
Evidence at protein level
[ "HPA052627" ]
[ "CT3.3", "MAGE-B5" ]
[ "Cancer-related genes", "Predicted intracellular proteins" ]
[]
[ "Tumor antigen" ]
[ "Cancer-related genes" ]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
null
null
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Group enriched
Detected in some
20
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,882
6
ENSG00000188419
CHM
CHM Rab escort protein
[ "P24386" ]
X
85861180-86047561
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003231", "CAB016171" ]
[ "DXS540", "REP-1", "TCD" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Sensory transduction", "Vision" ]
[ "GTPase activation" ]
[ "Disease variant" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
49
null
null
Cluster 14: Non-specific - Unknown function
Cluster 14: Neurons - Synaptic function
Cluster 36: Non-specific - mRNA processing
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
15,883
2
ENSG00000188425
NANOS2
Nanos C2HC-type zinc finger 2
[ "P60321" ]
19
45913214-45914778
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA014190" ]
[ "NOS2", "ZC2HC12B" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation", "Spermatogenesis", "Translation regulation" ]
[ "Developmental protein", "RNA-binding" ]
[]
[]
[]
[]
[]
null
Approved
null
5
null
null
null
null
null
Cluster 106: Spermatogonia - Spermatogonial differentiation
Cluster 23: Testis - Spermatogenesis
Tissue enriched
Detected in single
24
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
13
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,884
1
ENSG00000188428
BLOC1S5
Biogenesis of lysosomal organelles complex 1 subunit 5
[ "Q8TDH9" ]
6
8013567-8064396
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB025613", "HPA077525" ]
[ "dJ303A1.3", "MU", "MUTED" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[ "Albinism", "Hermansky-Pudlak syndrome" ]
[ "Vesicles" ]
[]
[]
[]
Supported
Uncertain
null
31
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 27: Non-specific - Mixed function
Cluster 28: Non-specific - Nuclear processes
Cluster 22: Non-specific - Basic cellular functions
Cluster 72: Kidney - Transmembrane transport
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
15,885
8
ENSG00000188452
CERKL
Ceramide kinase like
[ "Q49MI3" ]
2
181535041-181680665
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035443", "HPA035444", "HPA043203" ]
[ "RP26" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant", "Retinitis pigmentosa" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
2
null
null
null
Cluster 35: Non-specific - DNA binding
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
15,886
3
ENSG00000188467
SLC24A5
Solute carrier family 24 member 5
[ "Q71RS6" ]
15
48120990-48142672
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "JSX", "OCA6" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Antiport", "Calcium transport", "Ion transport", "Potassium transport", "Sensory transduction", "Sodium transport", "Symport", "Transport" ]
[]
[ "Albinism" ]
[]
[]
[]
[]
null
null
null
2
null
null
null
Cluster 19: Astrocytes - Mixed function
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 61: Schwann cells & Melanocytes - Mixed function
Cluster 37: Skin - Keratinization
Tissue enriched
Detected in some
5
Cancer enriched
Detected in some
63
Cancer enriched
Detected in some
18
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,887
2
ENSG00000188483
IER5L
Immediate early response 5 like
[ "Q5T953" ]
9
129175552-129178261
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA021327" ]
[ "bA247A12.2" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
null
null
1
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 20: Non-specific - Transcription regulation
Cluster 74: Non-specific - Signal transduction
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Lung Adenocarcinoma", "Lung Squamous Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Lung Adenocarcinoma", "Lung Squamous Cell Carcinoma" ]
15,888
5
ENSG00000188486
H2AX
H2A.X variant histone
[ "P16104" ]
11
119093874-119095465
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB012264", "HPA041189", "HPA051647" ]
[ "H2AFX" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "DNA damage", "DNA recombination", "DNA repair", "Host-virus interaction", "Meiosis" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Nuclear speckles" ]
[]
[]
Supported
Supported
null
219
Yes
Yes
Cluster 42: Non-specific - Vesicular transport
Cluster 13: Oligodendrocytes - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 20: Non-specific - Transcription regulation
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
15,889
5
ENSG00000188487
INSC
INSC spindle orientation adaptor protein
[ "Q1MX18" ]
11
15112424-15247208
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA039769" ]
[]
[ "Predicted intracellular proteins" ]
[ "Differentiation", "Neurogenesis" ]
[ "Developmental protein" ]
[]
[]
[]
[]
[]
null
Uncertain
null
11
null
null
Cluster 20: Non-specific - DNA binding
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 11: Neuronal - Sensory perception
Cluster 61: Schwann cells & Melanocytes - Mixed function
Cluster 69: Parathyroid gland - Mixed function
Tissue enriched
Detected in some
5
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,890
9
ENSG00000188488
SERPINA5
Serpin family A member 5
[ "P05154" ]
14
94561442-94593118
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA078846" ]
[ "PAI3", "PCI", "PLANH3", "PROCI" ]
[ "Cancer-related genes", "Candidate cardiovascular disease genes", "Plasma proteins", "Predicted secreted proteins" ]
[ "Fertilization", "Lipid transport", "Transport" ]
[ "Heparin-binding", "Protease inhibitor", "Serine protease inhibitor" ]
[ "Cancer-related genes" ]
[]
[]
[ "Secreted to blood" ]
[ "Transport" ]
null
Enhanced
null
5
null
null
null
Cluster 44: Non-specific - Mixed function
Cluster 18: Liver cancer - Metabolism
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
3
2
2
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
15,891
1
ENSG00000188493
C19orf54
Chromosome 19 open reading frame 54
[ "Q5BKX5" ]
19
40740856-40751553
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA059043", "HPA059628" ]
[ "FLJ41131" ]
[ "Predicted intracellular proteins" ]
[]
[ "Aminopeptidase", "Hydrolase", "Protease" ]
[]
[ "Intermediate filaments" ]
[ "Centriolar satellite" ]
[]
[]
Approved
Approved
null
null
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 6: Non-specific - Immune response
Cluster 54: Non-specific - Transcription
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 49: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
15,892
7
ENSG00000188501
LCTL
Lactase like
[ "Q6UWM7" ]
15
66547179-66565998
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA071640" ]
[ "FLJ33279", "KLG", "KLPH" ]
[ "Cancer-related genes", "Predicted membrane proteins" ]
[ "Sensory transduction", "Vision" ]
[]
[ "Cancer-related genes" ]
[ "Plasma membrane" ]
[ "Endoplasmic reticulum" ]
[]
[]
Approved
null
null
null
null
null
null
Cluster 30: White matter - Myelination
Cluster 69: Skin cancer - ECM organization
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 3: Oligodendrocytes - Myelination
Tissue enriched
Detected in single
4
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
15,893
1
ENSG00000188508
KRTDAP
Keratinocyte differentiation associated protein
[ "P60985" ]
19
35487324-35495558
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA063474" ]
[ "KDAP", "UNQ467" ]
[ "Plasma proteins", "Predicted secreted proteins" ]
[ "Differentiation" ]
[]
[]
[]
[]
[ "Secreted in other tissues" ]
[ "Other" ]
null
Enhanced
null
null
null
null
null
Cluster 32: Cerebral cortex - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 37: Skin - Keratinization
Tissue enhanced
Detected in many
null
Group enriched
Detected in some
17
Group enriched
Detected in many
4
Cell type enriched
Detected in many
7
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,895
3
ENSG00000188517
COL25A1
Collagen type XXV alpha 1 chain
[ "Q9BXS0" ]
4
108808725-109302752
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA029107" ]
[]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Heparin-binding" ]
[ "Disease variant" ]
[ "Vesicles", "Cytosol" ]
[ "Endoplasmic reticulum" ]
[]
[]
Approved
null
null
1
null
null
null
Cluster 29: Forebrain - Mixed function
Cluster 1: Neuronal - Visual perception
Cluster 91: Pituicytes/FSC - Homeostasis & neuron support
Cluster 47: Testis - Mixed function
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in some
null
Cell type enriched
Detected in many
10
Not detected in immune cells
Not detected
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
15,896
2
ENSG00000188522
FAM83G
Family with sequence similarity 83 member G
[ "A6ND36" ]
17
18968789-19004764
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA023369", "HPA023940" ]
[ "FLJ41564", "PAWS1" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Enhanced
null
19
null
null
Cluster 16: Non-specific - Cell proliferation
Cluster 44: Non-specific - Mixed function
Cluster 42: Non-specific - Unknown function
Cluster 26: Keratinocytes - Keratinization
Cluster 58: Skin - Keratinization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
2
0
2
[ "Stomach Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Stomach Adenocarcinoma" ]
15,897
3
ENSG00000188523
CFAP77
Cilia and flagella associated protein 77
[ "Q6ZQR2" ]
9
132410043-132573319
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA021329", "HPA061069" ]
[ "C9orf171", "FLJ46082" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
2
null
null
null
Cluster 3: Choroid plexus - Cilium
Cluster 10: Ciliated cells - Ion channel activity
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 56: Ciliated tissues - Cilium organization
Group enriched
Detected in some
7
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,898
6
ENSG00000188529
SRSF10
Serine and arginine rich splicing factor 10
[ "O75494" ]
1
23964347-23980927
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA053805", "HPA053831" ]
[ "FUSIP1", "FUSIP2", "PPP1R149", "SFRS13", "SFRS13A", "SRp38", "SRrp40", "TASR1", "TASR2" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing" ]
[ "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Uncertain
null
47
null
Yes
Cluster 42: Non-specific - Vesicular transport
Cluster 55: Non-specific - Transcription
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 15: Bone marrow - Innate immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
15,899
7
ENSG00000188536
HBA2
Hemoglobin subunit alpha 2
[ "P69905" ]
16
172876-173710
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB038417", "HPA043780" ]
[ "HBA-T2" ]
[ "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Transporters" ]
[ "Oxygen transport", "Transport" ]
[]
[ "Disease variant", "FDA approved drug targets", "Hereditary hemolytic anemia" ]
[]
[]
[]
[]
null
Enhanced
null
32
null
null
Cluster 22: Eosinophils - Transcription
Cluster 42: Choroid plexus - Mitochondria
Cluster 47: Leukemia - Hemostasis
Cluster 66: Erythroid cells - Erythroid differentiation and maturation
Cluster 15: Bone marrow - Innate immune response
Group enriched
Detected in all
5
Cancer enriched
Detected in many
34
Cancer enhanced
Detected in all
null
Cell type enriched
Detected in many
12
Group enriched
Detected in all
5
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
15,900
5
ENSG00000188542
DUSP28
Dual specificity phosphatase 28
[ "Q4G0W2" ]
2
240560054-240565256
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA047456", "CAB069448" ]
[ "DUSP26", "VHP" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Protein phosphatase" ]
[]
[ "Nuclear speckles" ]
[ "Cytosol" ]
[]
[]
Uncertain
Uncertain
null
null
null
null
Cluster 32: Basophils - Transcription
Cluster 15: Non-specific - Transcription
Cluster 56: Non-specific - Sensory perception
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
5
4
0
4
[ "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Skin Cutaneous Melanoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma", "Skin Cutaneous Melanoma" ]
15,901
4
ENSG00000188549
CCDC9B
Coiled-coil domain containing 9B
[ "Q6ZUT6" ]
15
40331452-40340939
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA040484", "HPA041834" ]
[ "C15orf52", "FLJ43339" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
1
null
null
null
Cluster 42: Choroid plexus - Mitochondria
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 55: Myocytes - Oxidative muscle function
Cluster 62: Skeletal muscle - Muscle contraction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Bladder Urothelial Carcinoma" ]
[]
[ "Bladder Urothelial Carcinoma" ]
15,902
3
ENSG00000188554
NBR1
NBR1 autophagy cargo receptor
[ "Q14596" ]
17
43170481-43211689
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA022944", "HPA022999", "HPA023999" ]
[ "1A1-3B", "CA125", "KIAA0049", "M17S2" ]
[ "Predicted intracellular proteins" ]
[ "Host-virus interaction" ]
[]
[]
[ "Vesicles" ]
[ "Nucleoplasm", "Nuclear bodies", "Cytosol" ]
[]
[]
Supported
Approved
null
52
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 13: Oligodendrocytes - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 21: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
4
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
15,903
5
ENSG00000188559
RALGAPA2
Ral GTPase activating protein catalytic subunit alpha 2
[ "Q2PPJ7" ]
20
20389530-20712644
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042707", "HPA043622" ]
[ "AS250", "C20orf74", "dJ1049G11.4", "KIAA1272", "RapGAPalpha2" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins", "RAS pathway related proteins" ]
[]
[ "GTPase activation" ]
[]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Supported
Uncertain
null
4
null
null
Cluster 29: Non-specific - Unknown function
Cluster 38: Sub-cortical - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Lung Squamous Cell Carcinoma" ]
[ "Lung Squamous Cell Carcinoma" ]
15,905
3
ENSG00000188573
FBLL1
Fibrillarin like 1
[ "A6NHQ2" ]
5
168529305-168530634
Evidence at protein level
Evidence at protein level
No human protein/transcript evidence
Evidence at protein level
[ "HPA049546", "HPA077724" ]
[ "LOC345630" ]
[ "Predicted intracellular proteins" ]
[ "rRNA processing" ]
[ "Methyltransferase", "Ribonucleoprotein", "RNA-binding", "Transferase" ]
[]
[ "Nucleoli fibrillar center" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Uncertain
null
null
null
null
null
Cluster 1: Neurons - Mixed function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
Cluster 10: Brain - Synaptic signal transduction
Group enriched
Detected in some
5
Cancer enriched
Detected in many
7
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,907
8
ENSG00000188580
NKAIN2
Sodium/potassium transporting ATPase interacting 2
[ "Q5VXU1" ]
6
123803865-124825640
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA045860" ]
[ "FAM77B", "TCBA1" ]
[ "Disease related genes", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
null
null
null
null
null
null
Cluster 30: White matter - Myelination
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 80: Oligodendrocytes - Myelination
Cluster 3: Oligodendrocytes - Myelination
Tissue enriched
Detected in some
14
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
19
0
0
0
[]
[]
[]
15,908
9
ENSG00000188581
KRTAP1-1
Keratin associated protein 1-1
[ "Q07627" ]
17
41040541-41041450
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "HB2A", "KAP1.1", "KAP1.1A", "KAP1.1B" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
150
null
null
null
null
Cluster 64: Connective tissue cells - ECM organization
null
Cluster 9: Skin - Hair follicle development
Tissue enriched
Detected in single
76
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,909
9
ENSG00000188582
PAQR9
Progestin and adipoQ receptor family member 9
[ "Q6ZVX9" ]
3
142949164-142963674
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA052798" ]
[ "BLNC1", "FLJ41938" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Receptor" ]
[]
[]
[]
[]
[]
null
Uncertain
null
2
null
null
null
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 47: Leukemia - Hemostasis
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 47: Testis - Mixed function
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in single
null
Cancer enriched
Detected in single
11
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
15,910
2
ENSG00000188585
CLEC20A
C-type lectin domain containing 20A
[ "Q6ZU45" ]
1
178479240-178499634
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[]
[ "FLJ44005", "LINC00083", "NCRNA00083", "RP4-593C16.2" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
Cluster 34: B-cells - Unknown function
null
Cluster 6: Leukemia - Signal transduction
Cluster 98: Neurons - Neurotransmission & signaling
Cluster 39: Testis - Nuclear processes
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
4
0
0
0
[]
[]
[]
15,911
9
ENSG00000188596
CFAP54
Cilia and flagella associated protein 54
[ "Q96N23" ]
12
96489571-96875555
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA039897" ]
[ "C12orf55", "C12orf63", "FLJ31514", "FLJ44112" ]
[ "Essential proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Cilium biogenesis/degradation", "Differentiation", "Spermatogenesis" ]
[]
[]
[ "Microtubules", "Cytokinetic bridge", "Primary cilium" ]
[ "Basal body", "Cytosol" ]
[]
[]
Approved
Enhanced
null
null
Yes
null
Cluster 20: Non-specific - DNA binding
Cluster 17: Choroid plexus - Cilium
Cluster 56: Non-specific - Sensory perception
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
1
0
1
[]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe" ]
15,912
2
ENSG00000188603
CLN3
CLN3 lysosomal/endosomal transmembrane protein, battenin
[ "Q13286" ]
16
28474111-28495575
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA063280" ]
[ "BTN1", "BTS", "JNCL" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Transport" ]
[]
[ "Disease variant", "Neurodegeneration", "Neuronal ceroid lipofuscinosis" ]
[]
[]
[]
[]
null
Uncertain
null
22
null
null
Cluster 29: Non-specific - Unknown function
Cluster 20: Macrophages & Microglia - Immune response
Cluster 27: Breast cancer - Unknown function
Cluster 22: Non-specific - Basic cellular functions
Cluster 60: Stomach - Digestion
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
15,913
7
ENSG00000188611
ASAH2
N-acylsphingosine amidohydrolase 2
[ "Q9NR71" ]
10
50182778-50279720
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA061171" ]
[]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Apoptosis", "Lipid metabolism", "Sphingolipid metabolism" ]
[ "Hydrolase" ]
[]
[ "Focal adhesion sites" ]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Approved
Supported
null
null
null
null
null
Cluster 45: Non-specific - Mixed function
Cluster 11: Neuronal - Sensory perception
Cluster 109: Neurons - Neuronal signaling
Cluster 7: Small intestine - Absorption and Digestion
Tissue enriched
Detected in some
11
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in some
null
Group enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,915
3
ENSG00000188612
SUMO2
Small ubiquitin like modifier 2
[ "P61956" ]
17
75165586-75182959
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB037314", "HPA042123", "HPA048064" ]
[ "SMT3B", "SMT3H2" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Host-virus interaction", "Ubl conjugation pathway" ]
[]
[]
[ "Nucleoplasm", "Nuclear bodies" ]
[ "Calyx", "Connecting piece", "Flagellar centriole" ]
[]
[]
Supported
Supported
null
139
null
null
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 31: Non-specific - Transcription
Cluster 27: Breast cancer - Unknown function
Cluster 15: Non-specific - Protein processing
Cluster 65: Brain - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
2
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
15,916
2
ENSG00000188613
NANOS1
Nanos C2HC-type zinc finger 1
[ "Q8WY41" ]
10
119029714-119033730
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB012219" ]
[ "NOS1", "ZC2HC12A" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Translation regulation" ]
[ "Repressor", "RNA-binding" ]
[ "Disease variant" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
3
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 30: Non-specific - Gene expression regulation
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma" ]
15,917
5
ENSG00000188620
HMX3
H6 family homeobox 3
[ "A6NHT5" ]
10
123135970-123139423
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA069659" ]
[ "NKX5-1" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Differentiation", "Neurogenesis", "Transcription", "Transcription regulation" ]
[ "Developmental protein", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Centriolar satellite" ]
[]
[]
Approved
null
null
1
Yes
No
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 24: Non-specific - Unknown function
Cluster 95: Tuft cells - Chemosensory signaling
Cluster 36: Brain & Liver - Signaling
Tissue enriched
Detected in single
5
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Cell type enriched
Detected in some
6
Low immune cell specificity
Detected in single
null
0
0
0
[]
[]
[]
15,918
7
ENSG00000188624
IGFL3
IGF like family member 3
[ "Q6UXB1" ]
19
46120067-46124688
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA062776" ]
[ "UNQ483" ]
[ "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted in other tissues" ]
[ "No annotated function" ]
null
Uncertain
null
null
null
null
null
Cluster 9: Non-specific - Receptor signaling
Cluster 5: Rhabdoid - Unknown function
Cluster 26: Keratinocytes - Keratinization
Cluster 37: Skin - Keratinization
Tissue enriched
Detected in some
18
Cancer enriched
Detected in some
7
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
15,919
7
ENSG00000188626
GOLGA8M
Golgin A8 family member M
[ "H3BSY2" ]
15
28698583-28738384
Evidence at transcript level
Evidence at transcript level
No human protein/transcript evidence
Evidence at transcript level
[]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 105: Non-specific - Mixed function
Cluster 21: Testis - Mixed function
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in single
16
Cancer enhanced
Detected in single
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,920
6
ENSG00000188629
ZNF177
Zinc finger protein 177
[ "Q13360" ]
19
9363013-9382617
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA003141" ]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 15: Non-specific - Transcription
Cluster 4: Non-specific - Transcription
Cluster 28: Astrocytes - Homeostasis & neuron support
Cluster 21: Testis - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Skin Cutaneous Melanoma" ]
[ "Skin Cutaneous Melanoma" ]
15,921
9
ENSG00000188636
RTL6
Retrotransposon Gag like 6
[ "Q6ICC9" ]
22
44492583-44498233
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA005697" ]
[ "dJ1033E15.2", "DKFZp761O17121", "LDOC1L", "Mar6", "Mart6", "SIRH3" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nuclear speckles" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
2
null
null
Cluster 33: Non-specific - ATP binding
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 10: Ciliated cells - Ion channel activity
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 65: Brain - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
15,922
6
ENSG00000188641
DPYD
Dihydropyrimidine dehydrogenase
[ "Q12882" ]
1
97077743-97995000
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB033241", "HPA045210" ]
[ "DHPDHase", "DPD" ]
[ "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Oxidoreductase" ]
[ "Disease variant", "FDA approved drug targets" ]
[]
[]
[]
[]
null
Uncertain
null
4
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 11: White matter - Signal transduction
Cluster 71: Lymphoma - Inflammatory response
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[]
[ "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
15,923
1
ENSG00000188643
S100A16
S100 calcium binding protein A16
[ "Q96FQ6" ]
1
153606886-153613145
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA045841" ]
[ "DT1P1A7", "MGC17528", "S100F" ]
[ "Predicted intracellular proteins", "Transporters" ]
[]
[]
[]
[ "Cytosol" ]
[ "Plasma membrane" ]
[]
[]
Approved
Enhanced
null
1
null
null
null
Cluster 44: Non-specific - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
5
Not detected in immune cells
Not detected
null
4
0
4
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
15,924
3
ENSG00000188647
PTAR1
Protein prenyltransferase alpha subunit repeat containing 1
[ "Q7Z6K3" ]
9
69709522-69760011
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA021248", "HPA022781" ]
[]
[ "Predicted intracellular proteins" ]
[]
[ "Prenyltransferase", "Transferase" ]
[]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
7
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 39: Astrocytes - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
15,925
2
ENSG00000188649
CC2D2B
Coiled-coil and C2 domain containing 2B
[ "Q6DHV5" ]
10
95907603-96033745
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA044091" ]
[ "bA248J23.4", "bA690P14.3", "C10orf130", "C10orf131" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Vesicles", "Basal body", "Cytosol" ]
[]
[]
Approved
Enhanced
null
null
null
null
Cluster 14: Non-specific - Unknown function
Cluster 26: Oligodendrocytes - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 40: Non-specific - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
15,926
4
ENSG00000188655
RNASE9
Ribonuclease A family member 9 (inactive)
[ "P60153" ]
14
20556093-20560931
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "h461", "RAK1" ]
[ "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted in male reproductive system" ]
[ "No annotated function" ]
null
null
null
null
null
null
null
null
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 30: Epididymal principal cells - Sperm storage microenvironment
Cluster 50: Epididymis - Male reproductive secretion
Tissue enriched
Detected in single
931
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
70
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
15,927
2