ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000198298
ZNF485
Zinc finger protein 485
[ "Q8NCK3" ]
10
43606419-43617904
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA059356" ]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[]
[]
[]
[]
null
Uncertain
null
6
null
null
Cluster 24: Non-specific - Transcription
Cluster 28: Oligodendrocytes - Mixed function
Cluster 52: Non-specific - Mitochondria
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Glioblastoma Multiforme" ]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma" ]
16,700
8
ENSG00000198301
SDAD1
SDA1 domain containing 1
[ "Q9NVU7" ]
4
75940950-75990962
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA035949" ]
[ "FLJ10498" ]
[ "Essential proteins", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Protein transport", "Ribosome biogenesis", "Transport" ]
[]
[]
[ "Nucleoplasm", "Nucleoli" ]
[]
[]
[]
Approved
Uncertain
null
40
null
null
Cluster 33: Non-specific - ATP binding
Cluster 14: Neurons - Synaptic function
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 17: Non-specific - RNA processing
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
16,702
2
ENSG00000198315
ZKSCAN8
Zinc finger with KRAB and SCAN domains 8
[ "Q15776" ]
6
28141883-28159460
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003483" ]
[ "LD5-1", "ZNF192", "ZSCAN40" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
31
null
null
Cluster 32: Basophils - Transcription
Cluster 50: Non-specific - Nucleic acid binding
Cluster 28: Non-specific - Nuclear processes
Cluster 7: Non-specific - Transcription
Cluster 49: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Rectum Adenocarcinoma" ]
[]
[ "Rectum Adenocarcinoma" ]
16,703
1
ENSG00000198324
PHETA1
PH domain containing endocytic trafficking adaptor 1
[ "Q8N4B1" ]
12
111360651-111369121
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FAM109A", "FLJ32356", "IPIP27A", "SES1" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
21
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 19: Astrocytes - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 7: Small intestine - Absorption and Digestion
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
16,704
6
ENSG00000198326
TMEM239
Transmembrane protein 239
[ "Q8WW34" ]
20
2816302-2820284
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
10
null
null
null
null
Cluster 21: Lymphoma - Adaptive immune response
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 79: Testis - Spermatogenesis
Tissue enriched
Detected in single
43
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
7
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,705
4
ENSG00000198331
HYLS1
HYLS1 centriolar and ciliogenesis associated
[ "Q96M11" ]
11
125883614-125900646
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041210" ]
[ "FLJ32915" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Cilium biogenesis/degradation" ]
[]
[ "Ciliopathy", "Disease variant" ]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Approved
Enhanced
null
1
null
Yes
Cluster 23: B-cells - Immunoglobulins
Cluster 5: Non-specific - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 67: Testis - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
16,706
5
ENSG00000198336
MYL4
Myosin light chain 4
[ "P12829" ]
17
47200446-47223679
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046859", "HPA051884", "HPA063034" ]
[ "ALC1", "AMLC", "GT1", "PRO1957" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Motor protein", "Muscle protein", "Myosin" ]
[ "Atrial fibrillation", "Disease variant" ]
[ "Plasma membrane" ]
[]
[]
[]
Approved
Enhanced
null
null
null
null
Cluster 44: Plasmacytoid DCs - Plasma membrane proteins
null
Cluster 47: Leukemia - Hemostasis
Cluster 66: Erythroid cells - Erythroid differentiation and maturation
Cluster 35: Non-specific - Mixed function
Tissue enriched
Detected in many
48
Group enriched
Detected in some
22
Cancer enriched
Detected in some
5
Group enriched
Detected in some
4
Immune cell enriched
Detected in single
9
0
0
0
[]
[]
[]
16,707
2
ENSG00000198342
ZNF442
Zinc finger protein 442
[ "Q9H7R0" ]
19
12345944-12365905
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA045738", "HPA053407" ]
[ "FLJ14356" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nuclear membrane" ]
[ "Vesicles" ]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 14: Non-specific - Unknown function
Cluster 49: Hindbrain - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 94: Gonadal somatic cells - Mixed function
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
16,708
1
ENSG00000198353
HOXC4
Homeobox C4
[ "P09017" ]
12
54016931-54056030
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA053910" ]
[ "HOX3", "HOX3E" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Developmental protein", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
null
null
30
null
null
null
Cluster 49: Hindbrain - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 75: Ovary - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,710
8
ENSG00000198355
PIM3
Pim-3 proto-oncogene, serine/threonine kinase
[ "Q86V86" ]
22
49960768-49964072
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA068758" ]
[]
[ "Cancer-related genes", "Enzymes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Apoptosis", "Cell cycle" ]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[ "Cancer-related genes", "Proto-oncogene" ]
[ "Cytosol" ]
[]
[]
[]
Supported
null
null
1
null
Yes
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 18: Non-specific - Mixed function
Cluster 66: Non-specific - Mitochondria
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
0
2
[]
[ "Ovary Serous Cystadenocarcinoma", "Thyroid Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma", "Thyroid Carcinoma" ]
16,712
8
ENSG00000198356
GET3
Guided entry of tail-anchored proteins factor 3, ATPase
[ "O43681" ]
19
12737139-12748323
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA045951", "HPA048087" ]
[ "ARSA-I", "ASNA1", "TRC40" ]
[ "Essential proteins", "Predicted intracellular proteins", "Transporters" ]
[ "Transport" ]
[ "Hydrolase" ]
[ "Cardiomyopathy", "Disease variant" ]
[ "Nucleoli" ]
[ "Nucleoplasm" ]
[]
[]
Enhanced
Approved
null
56
null
null
Cluster 29: Non-specific - Unknown function
Cluster 14: Neurons - Synaptic function
Cluster 23: Non-specific - Transcription
Cluster 97: Non-specific - Cellular respiration
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
16,713
5
ENSG00000198363
ASPH
Aspartate beta-hydroxylase
[ "Q12797" ]
8
61500556-61714640
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA055161", "HPA059303" ]
[ "BAH", "CASQ2BP1", "HAAH", "JCTN" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[]
[ "Dioxygenase", "Oxidoreductase" ]
[ "Cancer-related genes", "Disease variant" ]
[ "Endoplasmic reticulum" ]
[]
[]
[]
Enhanced
Uncertain
null
77
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 7: Liver cancer - Metabolism
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 63: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Immune cell enhanced
Detected in many
null
4
0
4
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
16,714
7
ENSG00000198373
WWP2
WW domain containing E3 ubiquitin protein ligase 2
[ "O00308" ]
16
69762328-69941741
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "AIP2" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Host-virus interaction", "Ubl conjugation pathway" ]
[ "Transferase" ]
[]
[]
[]
[]
[]
null
null
null
212
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 18: Non-specific - Mixed function
Cluster 68: Non-specific - Cell cycle regulation
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
16,716
8
ENSG00000198380
GFPT1
Glutamine--fructose-6-phosphate transaminase 1
[ "Q06210" ]
2
69319780-69387250
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047240" ]
[ "GFA", "GFAT", "GFAT1", "GFPT" ]
[ "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Biological rhythms" ]
[ "Aminotransferase", "Transferase" ]
[ "Congenital myasthenic syndrome", "Disease variant" ]
[ "Nucleoplasm", "Nucleoli" ]
[ "Nucleoli fibrillar center" ]
[]
[]
Approved
null
null
7
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 21: Non-specific - Metabolism
Cluster 13: Non-specific - Mixed function
Cluster 70: Intestinal goblet cells - Mucin production
Cluster 17: Intestine - Digestion
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Rectum Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
16,717
7
ENSG00000198382
UVRAG
UV radiation resistance associated
[ "Q9P2Y5" ]
11
75815210-76144232
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA016932" ]
[ "VPS38" ]
[ "Disease related genes", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair" ]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
65
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 50: Non-specific - Nucleic acid binding
Cluster 55: Lymphoma - Immune response
Cluster 82: Dendritic cells - Antigen presentation
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
16,718
1
ENSG00000198390
KRTAP13-1
Keratin associated protein 13-1
[ "Q8IUC0" ]
21
30396031-30396822
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[ "KAP13.1" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
null
null
Cluster 9: Skin - Hair follicle development
Tissue enriched
Detected in single
11
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,719
3
ENSG00000198393
ZNF26
Zinc finger protein 26
[ "P17031" ]
12
132986365-133032952
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA018329", "HPA042406" ]
[ "FLJ20755", "KOX20" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Mitochondria" ]
[ "Nuclear bodies" ]
[]
[]
Approved
Uncertain
null
4
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 48: Non-specific - Mixed function
Cluster 38: Non-specific - Transcription
Cluster 7: Non-specific - Transcription
Cluster 40: Non-specific - Mixed function
Low tissue specificity
Detected in some
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
16,720
5
ENSG00000198398
TMEM207
Transmembrane protein 207
[ "Q6UWW9" ]
3
190428655-190449901
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA014332" ]
[]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
9
null
null
null
null
Cluster 10: Ciliated cells - Ion channel activity
Cluster 50: Renal epithelial cells - Ion transport and pH regulation
Cluster 72: Kidney - Transmembrane transport
Tissue enriched
Detected in single
114
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
14
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,721
9
ENSG00000198399
ITSN2
Intersectin 2
[ "Q9NZM3" ]
2
24202864-24360536
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA036475" ]
[ "KIAA1256", "PRO2015", "SH3D1B", "SH3P18", "SWA", "SWAP" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation", "Endocytosis", "Host-virus interaction" ]
[]
[]
[ "Vesicles", "Plasma membrane" ]
[]
[]
[]
Approved
Approved
null
20
null
null
Cluster 20: Non-specific - DNA binding
Cluster 11: White matter - Signal transduction
Cluster 46: Lymphoma - Humoral immune response
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
16,722
8
ENSG00000198400
NTRK1
Neurotrophic receptor tyrosine kinase 1
[ "P04629" ]
1
156815636-156881850
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004606", "HPA035799", "HPA076570", "CAB080140" ]
[ "MTC", "TRK", "TRKA" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins", "RAS pathway related proteins" ]
[ "Differentiation", "Neurogenesis" ]
[ "Developmental protein", "Kinase", "Receptor", "Transferase", "Tyrosine-protein kinase" ]
[ "Cancer-related genes", "Disease variant", "FDA approved drug targets", "Proto-oncogene" ]
[ "Vesicles", "Cytosol" ]
[]
[]
[]
Approved
Enhanced
null
145
null
null
Cluster 46: Basophils - Proteolysis
Cluster 49: Hindbrain - Mixed function
Cluster 49: HMC-1 - Innate immune response
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 4: Adrenal gland - Steroid metabolism
Tissue enhanced
Detected in some
null
Group enriched
Detected in some
8
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Immune cell enriched
Detected in single
116
0
0
0
[]
[]
[]
16,723
6
ENSG00000198408
OGA
O-GlcNAcase
[ "O60502" ]
10
101784443-101818465
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036141", "HPA076501" ]
[ "MEA5", "MGEA5", "NCOAT" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Host-virus interaction" ]
[ "Glycosidase", "Hydrolase" ]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Approved
null
4
null
null
Cluster 20: Non-specific - DNA binding
Cluster 31: Non-specific - Transcription
Cluster 52: Non-specific - Mitochondria
Cluster 89: Adipocytes - Lipid metabolism
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Glioblastoma Multiforme" ]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Glioblastoma Multiforme" ]
16,724
5
ENSG00000198417
MT1F
Metallothionein 1F
[ "P04733" ]
16
56657731-56660698
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "MT1" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
1
null
null
Cluster 11: T-cells - Unknown function
Cluster 19: Astrocytes - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in all
5
3
2
2
[]
[ "Glioblastoma Multiforme", "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
16,725
4
ENSG00000198420
TCAF1
TRPM8 channel associated factor 1
[ "Q9Y4C2" ]
7
143851375-143902198
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA011732" ]
[ "FAM115A", "GATD9A", "KIAA0738" ]
[ "Predicted intracellular proteins" ]
[ "Transport" ]
[]
[]
[ "Cell Junctions" ]
[ "Nuclear bodies", "Vesicles" ]
[]
[]
Approved
Approved
null
16
null
null
Cluster 33: Non-specific - ATP binding
Cluster 33: Neurons - Mixed function
Cluster 18: Liver cancer - Metabolism
Cluster 102: Non-specific - Mixed function
Cluster 43: Placenta - Pregnancy hormone signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
16,726
4
ENSG00000198429
ZNF69
Zinc finger protein 69
[ "Q9UC07" ]
19
11887782-11914329
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA047845" ]
[ "Cos5" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Uncertain
Approved
null
2
null
null
Cluster 24: Non-specific - Transcription
Cluster 44: Non-specific - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 64: Renal epithelial cells - Ion transport & homeostasis
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
16,727
9
ENSG00000198431
TXNRD1
Thioredoxin reductase 1
[ "Q16881" ]
12
104215779-104350307
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001395", "CAB004607", "CAB015834", "HPA043871" ]
[ "GRIM-12", "Trxr1", "TXNR" ]
[ "Cancer-related genes", "Enzymes", "FDA approved drug targets", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Electron transport", "Transport" ]
[ "Oxidoreductase" ]
[ "Cancer-related genes", "FDA approved drug targets" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
null
9
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 21: Non-specific - Metabolism
Cluster 7: Liver cancer - Metabolism
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 4: Adrenal gland - Steroid metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
16,728
4
ENSG00000198435
NRARP
NOTCH regulated ankyrin repeat protein
[ "Q7Z6K4" ]
9
137299631-137302271
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA025729" ]
[ "MGC61598" ]
[ "Predicted intracellular proteins" ]
[]
[ "Developmental protein" ]
[]
[ "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Approved
null
1
null
null
null
Cluster 46: Brainstem - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 77: Intestine - Digestion
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma" ]
16,729
5
ENSG00000198440
ZNF583
Zinc finger protein 583
[ "Q96ND8" ]
19
56397966-56436035
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA023805", "HPA023957" ]
[ "FLJ31030" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoli" ]
[ "Cytosol" ]
[]
[]
Approved
Uncertain
null
1
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 16: Non-specific - Transcription
Cluster 4: Non-specific - Transcription
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
16,730
2
ENSG00000198443
KRTAP4-1
Keratin associated protein 4-1
[ "Q9BYQ7" ]
17
41184100-41184911
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "KAP4.1", "KAP4.10", "KRTAP4-10" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
22
null
null
null
null
Cluster 7: Liver cancer - Metabolism
Cluster 70: Intestinal goblet cells - Mucin production
Cluster 9: Skin - Hair follicle development
Tissue enriched
Detected in single
47
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,731
6
ENSG00000198445
CCT8L2
Chaperonin containing TCP1 subunit 8 like 2
[ "Q96SF2" ]
22
16590751-16592810
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[ "CESK1" ]
[ "Predicted intracellular proteins" ]
[]
[ "Chaperone" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
null
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 79: Testis - Spermatogenesis
Tissue enriched
Detected in single
202
Not detected
Not detected
null
Not detected
Not detected
null
Group enriched
Detected in some
57
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,732
9
ENSG00000198452
OR14L1P
Olfactory receptor family 14 subfamily L member 1 pseudogene
[]
1
247617143-247622372
Evidence at transcript level
Evidence at transcript level
null
null
[]
[ "OR5AV1", "OR5AV1P" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
Cluster 46: Basophils - Proteolysis
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 49: HMC-1 - Innate immune response
Cluster 58: Mast cells - Allergic inflammatory responses
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Immune cell enriched
Detected in single
53
0
0
0
[]
[]
[]
16,733
6
ENSG00000198453
ZNF568
Zinc finger protein 568
[ "Q3ZCX4" ]
19
36916316-37005037
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA024541", "HPA052061" ]
[ "DKFZp686B0797" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Developmental protein", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 32: Basophils - Transcription
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 4: Non-specific - Transcription
Cluster 102: Non-specific - Mixed function
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Skin Cutaneous Melanoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Skin Cutaneous Melanoma" ]
16,734
5
ENSG00000198464
ZNF480
Zinc finger protein 480
[ "Q8WV37" ]
19
52297169-52325922
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042218" ]
[ "MGC32104" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Uncertain
null
2
null
null
Cluster 30: Non-specific - DNA binding
Cluster 9: Non-specific - Receptor signaling
Cluster 4: Non-specific - Transcription
Cluster 7: Non-specific - Transcription
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma", "Skin Cutaneous Melanoma", "Stomach Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma", "Skin Cutaneous Melanoma", "Stomach Adenocarcinoma" ]
16,736
4
ENSG00000198466
ZNF587
Zinc finger protein 587
[ "Q96SQ5" ]
19
57849859-57865117
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042125", "HPA043288", "HPA056213" ]
[ "FLJ14710", "FLJ20813", "UBF-fl", "ZF6" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Nucleoli" ]
[]
[]
Approved
Uncertain
null
102
null
null
Cluster 32: Basophils - Transcription
Cluster 48: Non-specific - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 8: Non-specific - Secretory pathway
Cluster 77: Intestine - Digestion
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
1
0
1
[ "Rectum Adenocarcinoma" ]
[]
[ "Rectum Adenocarcinoma" ]
16,737
9
ENSG00000198467
TPM2
Tropomyosin 2
[ "P07951" ]
9
35681992-35690056
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA047089", "HPA053624" ]
[ "AMCD1", "DA1", "NEM4" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Actin-binding", "Muscle protein" ]
[ "Cancer-related genes", "Disease variant", "Nemaline myopathy" ]
[]
[]
[]
[]
null
Approved
null
12
null
null
Cluster 44: Plasmacytoid DCs - Plasma membrane proteins
Cluster 23: Choroid plexus - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 62: Smooth muscle cells - Muscle contraction
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
811
2
0
2
[]
[ "Colon Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
16,738
5
ENSG00000198471
RTP2
Receptor transporter protein 2
[ "Q5QGT7" ]
3
187698259-187702557
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "MGC78665", "Z3CXXC2" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
65
null
null
null
null
Cluster 27: Breast cancer - Unknown function
Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase
Cluster 25: Non-specific - Basic cellular processes
Group enriched
Detected in some
16
Not detected
Not detected
null
Cancer enriched
Detected in single
11
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,739
3
ENSG00000198478
SH3BGRL2
SH3 domain binding glutamate rich protein like 2
[ "Q9UJC5" ]
6
79631329-79703655
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047486" ]
[]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
null
2
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 24: Neurons - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 84: Apical squamous epithelium - Cornification
Cluster 60: Stomach - Digestion
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Group enriched
Detected in many
4
Immune cell enriched
Detected in some
5
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Rectum Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
16,740
2
ENSG00000198482
ZNF808
Zinc finger protein 808
[ "Q8N4W9" ]
19
52527652-52564464
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription" ]
[ "DNA-binding" ]
[ "Disease variant" ]
[]
[]
[]
[]
null
null
null
null
null
null
Cluster 32: Basophils - Transcription
Cluster 44: Non-specific - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 7: Non-specific - Transcription
Cluster 40: Non-specific - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
16,741
4
ENSG00000198483
ANKRD35
Ankyrin repeat domain 35
[ "Q8N283" ]
1
145866560-145885866
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA035453" ]
[ "FLJ25124" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Plasma membrane" ]
[ "Nucleoplasm", "Vesicles", "Primary cilium", "Primary cilium transition zone", "Basal body" ]
[]
[]
Approved
Enhanced
null
3
null
null
Cluster 33: Non-specific - ATP binding
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 108: Fibroblasts - ECM organization
Cluster 58: Skin - Keratinization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
1
0
1
[ "Breast Invasive Carcinoma" ]
[]
[ "Breast Invasive Carcinoma" ]
16,742
9
ENSG00000198488
B3GNT6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
[ "Q6ZMB0" ]
11
77034398-77041973
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039805" ]
[ "B3Gn-T6" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Glycosyltransferase", "Transferase" ]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
null
Enhanced
null
null
null
null
null
Cluster 34: Non-specific - Mixed function
Cluster 2: Mucus-secreting cells - Unknown function
Cluster 70: Intestinal goblet cells - Mucin production
Cluster 17: Intestine - Digestion
Group enriched
Detected in some
5
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Lung Adenocarcinoma", "Rectum Adenocarcinoma" ]
[ "Lung Adenocarcinoma", "Rectum Adenocarcinoma" ]
16,743
7
ENSG00000198492
YTHDF2
YTH N6-methyladenosine RNA binding protein 2
[ "Q9Y5A9" ]
1
28736621-28769775
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA030063", "HPA054080", "HPA059621" ]
[ "CAHL", "HGRG8", "NY-REN-2" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "Differentiation", "Host-virus interaction", "Immunity", "Innate immunity", "Mitosis", "Oogenesis", "Spermatogenesis" ]
[ "RNA-binding" ]
[]
[ "Cytosol" ]
[ "Cytoplasmic bodies" ]
[]
[]
Enhanced
Approved
null
71
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 23: Choroid plexus - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
16,744
9
ENSG00000198498
TMA16
Translation machinery associated 16 homolog
[ "Q96EY4" ]
4
163494442-163520539
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041571", "HPA052688" ]
[ "C4orf43", "FLJ11184" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Ribosome biogenesis" ]
[]
[]
[ "Nucleoli" ]
[ "Nucleoplasm" ]
[]
[]
Enhanced
Uncertain
null
16
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 28: Oligodendrocytes - Mixed function
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 17: Non-specific - RNA processing
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
2
3
[]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
16,745
2
ENSG00000198502
HLA-DRB5
Major histocompatibility complex, class II, DR beta 5
[ "Q30154" ]
6
32517353-32530287
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043151" ]
[]
[ "Human disease related genes", "Predicted membrane proteins" ]
[ "Adaptive immunity", "Immunity" ]
[]
[]
[]
[]
[]
[]
null
Supported
null
11
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 20: Macrophages & Microglia - Immune response
Cluster 21: Lymphoma - Adaptive immune response
Cluster 82: Dendritic cells - Antigen presentation
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
0
0
0
[]
[]
[]
16,746
4
ENSG00000198513
ATL1
Atlastin GTPase 1
[ "Q8WXF7" ]
14
50532509-50634017
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA027550" ]
[ "AD-FSP", "FSP1", "SPG3", "SPG3A" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[]
[ "Hydrolase" ]
[ "Disease variant", "Hereditary spastic paraplegia", "Neurodegeneration", "Neuropathy" ]
[]
[]
[]
[]
null
Enhanced
null
28
null
null
Cluster 46: Basophils - Proteolysis
Cluster 14: Neurons - Synaptic function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 109: Neurons - Neuronal signaling
Cluster 73: Brain - Neuronal signaling
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
4
3
2
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
16,747
8
ENSG00000198515
CNGA1
Cyclic nucleotide gated channel subunit alpha 1
[ "P29973" ]
4
47935977-48016681
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA076168" ]
[ "CNCG", "CNCG1", "CNG1", "RCNC1", "RCNCa", "RP49" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters", "Voltage-gated ion channels" ]
[ "Calcium transport", "Ion transport", "Sensory transduction", "Sodium transport", "Transport", "Vision" ]
[ "Calcium channel", "Ion channel", "Ligand-gated ion channel", "Sodium channel" ]
[ "Disease variant", "Retinitis pigmentosa" ]
[ "Nucleoplasm", "Vesicles", "Mid piece", "Principal piece" ]
[ "Plasma membrane", "Mitotic spindle", "Primary cilium", "Primary cilium tip" ]
[]
[]
Uncertain
null
null
null
Yes
null
null
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 42: Retina - Visual perception
Tissue enriched
Detected in many
11
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in many
4
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
16,748
1
ENSG00000198517
MAFK
MAF bZIP transcription factor K
[ "O60675" ]
7
1530702-1543043
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB026820", "HPA060841" ]
[ "NFE2U", "P18" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Repressor" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Enhanced
null
11
No
No
Cluster 22: Eosinophils - Transcription
Cluster 18: Non-specific - Mixed function
Cluster 67: Non-specific - Unknown function
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
2
0
2
[ "Rectum Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Rectum Adenocarcinoma" ]
16,749
6
ENSG00000198520
ARMH1
Armadillo like helical domain containing 1
[ "Q6PIY5" ]
1
44674692-44725591
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA034769", "HPA034770" ]
[ "C1orf228", "MGC33556", "NCRNA00082", "p40" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Enhanced
Uncertain
null
null
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 3: Choroid plexus - Cilium
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
0
0
0
[]
[]
[]
16,750
8
ENSG00000198521
ZNF43
Zinc finger protein 43
[ "P17038" ]
19
21804946-21852125
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA050271" ]
[ "HTF6", "KOX27", "ZNF39L1" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
Cluster 32: Basophils - Transcription
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 4: Non-specific - Transcription
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Colon Adenocarcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Chromophobe" ]
[ "Colon Adenocarcinoma", "Kidney Chromophobe", "Lung Adenocarcinoma" ]
16,751
6
ENSG00000198522
GPN1
GPN-loop GTPase 1
[ "Q9HCN4" ]
2
27628247-27651511
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036793", "HPA036794", "CAB037303" ]
[ "ATPBD1A", "MBDIN", "NTPBP", "RPAP4", "XAB1" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[ "Hydrolase" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[ "Mitochondria" ]
[]
[]
Supported
Uncertain
null
79
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 21: Non-specific - Metabolism
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
16,752
2
ENSG00000198523
PLN
Phospholamban
[ "P26678" ]
6
118548296-118561716
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB005597", "HPA026900" ]
[ "CMD1P", "PLB" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[]
[]
[ "Cardiomyopathy", "Disease variant" ]
[]
[]
[]
[]
null
Enhanced
null
53
null
null
null
Cluster 15: Non-specific - Transcription
Cluster 69: Skin cancer - ECM organization
Cluster 62: Smooth muscle cells - Muscle contraction
Cluster 35: Non-specific - Mixed function
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in single
6
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Squamous Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
16,753
9
ENSG00000198535
C2CD4A
C2 calcium dependent domain containing 4A
[ "Q8NCU7" ]
15
62066977-62070917
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA078864" ]
[ "FAM148A", "NLF1" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Nucleoli" ]
[]
[]
Supported
null
null
null
null
null
null
Cluster 1: Neurons - Mixed function
Cluster 2: Mucus-secreting cells - Unknown function
Cluster 51: Secretory epithelial cells - Mixed function
Cluster 70: Non-specific - Protein processing
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in many
6
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
16,754
9
ENSG00000198538
ZNF28
Zinc finger protein 28
[ "P17035" ]
19
52797408-52857600
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "DKFZp781D0275", "KOX24" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
Cluster 41: Basophils - Unknown function
Cluster 25: Non-specific - Transcription
Cluster 4: Non-specific - Transcription
Cluster 7: Non-specific - Transcription
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
16,755
4
ENSG00000198542
ITGBL1
Integrin subunit beta like 1
[ "O95965" ]
13
101452593-101720856
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[ "OSCP", "TIED" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins", "Transporters" ]
[]
[]
[]
[]
[]
[ "Secreted - unknown location" ]
[ "No annotated function" ]
null
null
null
null
null
null
null
Cluster 25: Non-specific - Transcription
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enriched
Detected in many
4
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[]
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
16,756
6
ENSG00000198546
ZNF511
Zinc finger protein 511
[ "Q8NB15" ]
10
133308914-133313162
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA035360" ]
[ "MGC30006", "Zfp511" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nuclear bodies" ]
[ "Nucleoplasm", "Vesicles" ]
[]
[]
Approved
Uncertain
null
14
null
null
Cluster 29: Non-specific - Unknown function
Cluster 27: Non-specific - Mixed function
Cluster 52: Non-specific - Mitochondria
Cluster 97: Non-specific - Cellular respiration
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
16,757
5
ENSG00000198547
C20orf203
Chromosome 20 open reading frame 203
[ "Q8NBC4" ]
20
32631625-32673941
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[]
[ "FLJ33706" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 37: Neurons - Mixed function
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 109: Neurons - Neuronal signaling
Cluster 65: Brain - Transcription
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Immune cell enriched
Detected in single
5
0
0
0
[]
[]
[]
16,758
1
ENSG00000198551
ZNF627
Zinc finger protein 627
[ "Q7L945" ]
19
11559374-11619161
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049770", "HPA073463" ]
[ "FLJ90365" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Nucleoli" ]
[]
[]
Approved
Uncertain
null
9
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 55: Non-specific - Transcription
Cluster 23: Non-specific - Transcription
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
16,759
7
ENSG00000198553
KCNRG
Potassium channel regulator
[ "Q8N5I3" ]
13
50015254-50020922
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA001027" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Golgi apparatus", "Vesicles" ]
[ "Basal body" ]
[]
[]
Uncertain
null
null
2
null
null
Cluster 20: Non-specific - DNA binding
Cluster 6: Non-specific - Immune response
Cluster 60: Prostate cancer - Unknown function
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enriched
Detected in some
11
Low cancer specificity
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in single
null
0
0
0
[]
[]
[]
16,760
2
ENSG00000198554
WDHD1
WD repeat and HMG-box DNA binding protein 1
[ "O75717" ]
14
54938949-55027105
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000632", "HPA001122" ]
[ "AND-1", "CHTF4", "CTF4" ]
[ "Essential proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Enhanced
null
17
null
Yes
Cluster 5: Non-specific - Cell proliferation
Cluster 34: Non-specific - Mixed function
Cluster 30: Non-specific - Gene expression regulation
Cluster 66: Erythroid cells - Erythroid differentiation and maturation
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
16,761
1
ENSG00000198556
ZNF789
Zinc finger protein 789
[ "Q5FWF6" ]
7
99472890-99503650
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA029500", "HPA050793" ]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Uncertain
null
1
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 39: Non-specific - Transcription
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Pancreatic Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
16,762
8
ENSG00000198561
CTNND1
Catenin delta 1
[ "O60716" ]
11
57753243-57819546
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB003837", "HPA015954", "HPA015955" ]
[ "CTNND", "KIAA0384", "p120", "p120cas", "p120ctn" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Transporters" ]
[ "Cell adhesion", "Transcription", "Transcription regulation", "Wnt signaling pathway" ]
[]
[ "Cancer-related genes", "Disease variant", "Ectodermal dysplasia" ]
[ "Plasma membrane" ]
[ "Basal body" ]
[]
[]
Enhanced
Enhanced
null
67
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 8: Immune cells - Immune response
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 102: Non-specific - Mixed function
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
5
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
16,763
1
ENSG00000198563
DDX39B
DExD-box helicase 39B
[ "Q13838" ]
6
31530219-31542448
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB034012", "HPA055334", "HPA058450" ]
[ "BAT1", "D6S81E", "UAP56" ]
[ "Enzymes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins", "Transporters" ]
[ "mRNA processing", "mRNA splicing", "mRNA transport", "Transport" ]
[ "Helicase", "Hydrolase", "RNA-binding" ]
[]
[ "Nuclear speckles" ]
[]
[]
[]
Enhanced
Enhanced
null
193
null
null
Cluster 33: Non-specific - ATP binding
Cluster 55: Non-specific - Transcription
Cluster 28: Non-specific - Nuclear processes
Cluster 22: Non-specific - Basic cellular functions
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in some
10
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
16,764
6
ENSG00000198569
SLC34A3
Solute carrier family 34 member 3
[ "Q8N130" ]
9
137230757-137236555
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA023776" ]
[ "FLJ38680", "NPTIIc" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Sodium transport", "Symport", "Transport" ]
[]
[ "Disease variant" ]
[]
[]
[]
[]
null
Enhanced
null
4
null
null
null
Cluster 39: Astrocytes - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 72: Kidney - Transmembrane transport
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in single
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,765
5
ENSG00000198570
RD3
RD3 regulator of GUCY2D
[ "Q7Z3Z2" ]
1
211476522-211492162
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA029941", "HPA029943" ]
[ "C1orf36", "LCA12" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Sensory transduction", "Vision" ]
[]
[ "Leber congenital amaurosis" ]
[]
[]
[]
[]
null
Enhanced
null
5
null
null
null
Cluster 48: Non-specific - Mixed function
Cluster 1: Neuronal - Visual perception
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 42: Retina - Visual perception
Tissue enriched
Detected in some
27
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in single
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,766
4
ENSG00000198573
SPANXC
SPANX family member C
[ "Q9NY87" ]
X
141241463-141242517
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046423", "HPA073647" ]
[ "CT11.3", "CTp11" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Approved
Supported
null
2
null
null
null
Cluster 28: Oligodendrocytes - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 73: Late spermatids - Spermiogenesis: Maturation
Cluster 79: Testis - Spermatogenesis
Tissue enriched
Detected in single
305
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,767
3
ENSG00000198574
SH2D1B
SH2 domain containing 1B
[ "O14796" ]
1
162395268-162412138
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA054791" ]
[ "EAT2" ]
[ "Predicted intracellular proteins" ]
[ "Adaptive immunity", "Immunity", "Innate immunity" ]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
20
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 53: Neurons - Mixed function
Cluster 50: Lymphoma - Unknown function
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 63: Non-specific - Basic cellular processes
Tissue enhanced
Detected in some
null
Cancer enriched
Detected in single
6
Not detected
Not detected
null
Group enriched
Detected in some
4
Group enriched
Detected in many
8
0
0
0
[]
[]
[]
16,768
1
ENSG00000198576
ARC
Activity regulated cytoskeleton associated protein
[ "Q7LC44" ]
8
142611049-142614479
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA056430", "CAB079013" ]
[ "Arg3.1", "KIAA0278" ]
[ "Predicted intracellular proteins" ]
[ "Endocytosis", "Transport" ]
[ "Developmental protein", "RNA-binding" ]
[]
[ "Vesicles", "Microtubules" ]
[]
[]
[]
Approved
null
Supported
6
null
null
null
Cluster 29: Forebrain - Mixed function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 91: Pituicytes/FSC - Homeostasis & neuron support
Cluster 36: Brain & Liver - Signaling
Tissue enhanced
Detected in many
null
Group enriched
Detected in many
6
Cancer enriched
Detected in many
13
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
16,769
8
ENSG00000198585
NUDT16
Nudix hydrolase 16
[ "Q96DE0" ]
3
131381671-131388830
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA060452", "HPA062492" ]
[ "FLJ31265" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Nucleotide metabolism" ]
[ "Hydrolase", "RNA-binding" ]
[]
[ "Nucleoplasm", "Nucleoli" ]
[]
[]
[]
Supported
Uncertain
null
4
null
null
Cluster 25: Non-specific - Unknown function
Cluster 19: Astrocytes - Mixed function
Cluster 63: Non-specific - Protein processing
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 3: Oligodendrocytes - Myelination
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in all
4
5
0
5
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Rectum Adenocarcinoma" ]
16,770
8
ENSG00000198586
TLK1
Tousled like kinase 1
[ "Q9UKI8" ]
2
170990823-171231314
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA016043" ]
[ "KIAA0137", "PKU-BETA" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Cell cycle", "DNA damage" ]
[ "Chromatin regulator", "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
null
30
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 38: Sub-cortical - Mixed function
Cluster 7: Liver cancer - Metabolism
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
16,771
8
ENSG00000198589
LRBA
LPS responsive beige-like anchor protein
[ "P50851" ]
4
150264435-151015727
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019366", "HPA023597" ]
[ "BGL", "CDC4L", "LAB300", "LBA" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant" ]
[ "Golgi apparatus" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
7
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 50: Non-specific - Nucleic acid binding
Cluster 46: Lymphoma - Humoral immune response
Cluster 51: Secretory epithelial cells - Mixed function
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
16,772
8
ENSG00000198597
ZNF536
Zinc finger protein 536
[ "O15090" ]
19
30224891-30713586
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA077341" ]
[ "KIAA0390" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm", "Cell Junctions" ]
[]
[]
[]
Approved
null
null
7
null
null
null
Cluster 11: White matter - Signal transduction
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 80: Oligodendrocytes - Myelination
Cluster 3: Oligodendrocytes - Myelination
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,773
2
ENSG00000198598
MMP17
Matrix metallopeptidase 17
[ "Q9ULZ9" ]
12
131828393-131851783
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "MT4-MMP" ]
[ "Enzymes", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Hydrolase", "Metalloprotease", "Protease" ]
[]
[]
[]
[ "Secreted to extracellular matrix" ]
[ "Enzyme" ]
null
null
null
null
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 51: Neurons - Mixed function
Cluster 69: Skin cancer - ECM organization
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 78: Brain - Neuronal signaling
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in many
5
Cancer enriched
Detected in many
9
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
16,774
7
ENSG00000198601
OR2M2
Olfactory receptor family 2 subfamily M member 2
[ "Q96R28" ]
1
248174821-248181067
Evidence at transcript level
Evidence at transcript level
No human protein/transcript evidence
No human protein/transcript evidence
[]
[ "OR2M2Q", "OST423" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 24: Neurons - Mixed function
null
Cluster 109: Neurons - Neuronal signaling
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,775
4
ENSG00000198604
BAZ1A
Bromodomain adjacent to zinc finger domain 1A
[ "Q9NRL2" ]
14
34752731-34875647
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA002730" ]
[ "ACF1", "hACF1", "WALp1", "WCRF180" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[]
[]
[]
[]
[]
[]
null
Supported
null
39
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 11: White matter - Signal transduction
Cluster 30: Non-specific - Gene expression regulation
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
5
0
5
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
16,776
8
ENSG00000198610
AKR1C4
Aldo-keto reductase family 1 member C4
[ "P17516" ]
10
5195462-5218949
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044720", "HPA068265" ]
[ "3-alpha-HSD", "C11", "CDR", "CHDR", "DD4", "HAKRA", "MGC22581" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Lipid metabolism" ]
[ "Oxidoreductase" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[ "Nucleoli fibrillar center", "Endoplasmic reticulum" ]
[]
[]
Approved
Uncertain
null
4
null
null
null
null
Cluster 7: Liver cancer - Metabolism
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 45: Liver - Metabolism & Coagulation
Tissue enriched
Detected in some
17
Group enriched
Detected in some
4
Cancer enriched
Detected in many
87
Cell type enriched
Detected in some
27
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
16,777
5
ENSG00000198612
COPS8
COP9 signalosome subunit 8
[ "Q99627" ]
2
237085882-237100474
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036485" ]
[ "COP9", "CSN8", "MGC1297", "SGN8" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Uncertain
null
82
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 14: Neurons - Synaptic function
Cluster 44: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
5
Low immune cell specificity
Detected in all
null
4
2
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
16,778
5
ENSG00000198624
CCDC69
Coiled-coil domain containing 69
[ "A6NI79" ]
5
151181052-151224093
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043648", "HPA052896" ]
[ "DKFZP434C171", "FLJ13705" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Plasma membrane" ]
[ "Golgi apparatus", "Actin filaments" ]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 49: Hindbrain - Mixed function
Cluster 46: Lymphoma - Humoral immune response
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 63: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Group enriched
Detected in many
9
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Squamous Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
16,779
8
ENSG00000198625
MDM4
MDM4 regulator of p53
[ "O15151" ]
1
204516379-204558120
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA018919", "HPA048821" ]
[ "HDMX", "MDMX" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Cancer-related genes", "Disease variant" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
null
65
null
null
Cluster 29: Non-specific - Unknown function
Cluster 50: Non-specific - Nucleic acid binding
Cluster 45: Non-specific - Nuclear processes
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Prostate Adenocarcinoma" ]
[ "Prostate Adenocarcinoma" ]
16,780
4
ENSG00000198626
RYR2
Ryanodine receptor 2
[ "Q92736" ]
1
237042184-237833988
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA020028" ]
[ "ARVC2", "ARVD2", "VTSIP" ]
[ "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Calcium transport", "Ion transport", "Transport" ]
[ "Calcium channel", "Calmodulin-binding", "Developmental protein", "Ion channel", "Ligand-gated ion channel", "Receptor" ]
[ "Cardiomyopathy", "Disease variant", "FDA approved drug targets" ]
[ "Plasma membrane" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
Uncertain
Approved
null
13
null
null
null
Cluster 34: Non-specific - Mixed function
Cluster 71: Lymphoma - Inflammatory response
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 35: Non-specific - Mixed function
Tissue enriched
Detected in many
8
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Cell type enriched
Detected in many
17
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,781
2
ENSG00000198642
KLHL9
Kelch like family member 9
[ "Q9P2J3" ]
9
21329665-21335404
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA046039", "HPA059901" ]
[ "FLJ13568", "KIAA1354" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "Mitosis", "Ubl conjugation pathway" ]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Approved
null
50
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 55: Non-specific - Transcription
Cluster 43: Non-specific - Basic cellular processes
Cluster 17: Non-specific - RNA processing
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
16,783
9
ENSG00000198643
FAM3D
FAM3 metabolism regulating signaling molecule D
[ "Q96BQ1" ]
3
58633946-58666834
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA013844" ]
[ "EF7", "OIT1" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted to digestive system" ]
[ "No annotated function" ]
null
Approved
null
4
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
null
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 84: Apical squamous epithelium - Cornification
Cluster 11: Esophagus - Basic cellular processes
Group enriched
Detected in many
5
Group enriched
Detected in some
6
Cancer enhanced
Detected in many
null
Cell type enriched
Detected in many
4
Immune cell enhanced
Detected in single
null
0
0
0
[]
[]
[]
16,784
1
ENSG00000198646
NCOA6
Nuclear receptor coactivator 6
[ "Q14686" ]
20
34689097-34825651
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA004198", "HPA050211" ]
[ "AIB3", "ASC2", "KIAA0181", "NRC", "PRIP", "RAP250", "TRBP" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Supported
null
63
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 4: Non-specific - mRNA splicing & Cell cycle
Cluster 62: Non-specific - Plasma proteins
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 32: Retina & Lymphoid tissues - Signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
16,785
8
ENSG00000198648
STK39
Serine/threonine kinase 39
[ "Q9UEW8" ]
2
167954020-168247595
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB046022", "HPA061803", "HPA062802" ]
[ "DCHT", "SPAK" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Nucleoplasm" ]
[ "Vesicles", "Cytosol" ]
[]
[]
Supported
Enhanced
null
11
null
null
Cluster 15: NK-cells - Unknown function
Cluster 28: Oligodendrocytes - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 38: Secretory epithelial cells - Exocrine secretion
Cluster 60: Stomach - Digestion
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
16,786
1
ENSG00000198650
TAT
Tyrosine aminotransferase
[ "P17735" ]
16
71565660-71577092
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Phenylalanine catabolism", "Tyrosine catabolism" ]
[ "Aminotransferase", "Transferase" ]
[ "Disease variant", "Intellectual disability", "Palmoplantar keratoderma" ]
[]
[]
[]
[]
null
null
null
7
null
null
null
Cluster 9: Non-specific - Receptor signaling
Cluster 27: Breast cancer - Unknown function
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 45: Liver - Metabolism & Coagulation
Tissue enriched
Detected in some
21
Cancer enhanced
Detected in single
null
Cancer enriched
Detected in some
8
Cell type enriched
Detected in some
30
Not detected in immune cells
Not detected
null
1
2
0
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
16,787
6
ENSG00000198663
C6orf89
Chromosome 6 open reading frame 89
[ "Q6UWU4" ]
6
36871870-36928964
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA012548" ]
[ "BRAP", "FLJ25357" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 27: Non-specific - Mixed function
Cluster 28: Non-specific - Nuclear processes
Cluster 73: Late spermatids - Spermiogenesis: Maturation
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in all
4
Low immune cell specificity
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
16,788
5
ENSG00000198668
CALM1
Calmodulin 1
[ "P0DP23" ]
14
90396502-90408268
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB018558", "HPA044999" ]
[ "CALML2", "CAMI", "DD132", "PHKD", "PHKD1" ]
[ "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins", "RAS pathway related proteins" ]
[ "Host-virus interaction" ]
[]
[ "Disease variant", "FDA approved drug targets", "Long QT syndrome" ]
[ "Cytosol" ]
[]
[]
[]
Supported
Supported
null
234
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 14: Neurons - Synaptic function
Cluster 30: Non-specific - Gene expression regulation
Cluster 20: Non-specific - Transcription regulation
Cluster 10: Brain - Synaptic signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
16,789
5
ENSG00000198670
LPA
Lipoprotein(a)
[ "P08519" ]
6
160531482-160664275
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB016072", "HPA060604" ]
[ "LP", "Lp(a)" ]
[ "Candidate cardiovascular disease genes", "Enzymes", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Lipid transport", "Transport" ]
[ "Hydrolase", "Protease", "Serine protease" ]
[ "Atherosclerosis" ]
[]
[]
[ "Secreted to blood" ]
[ "Transport" ]
null
Supported
null
7
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 59: Leukemia - T-cell receptor
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 45: Liver - Metabolism & Coagulation
Tissue enriched
Detected in some
65
Not detected
Not detected
null
Cancer enriched
Detected in single
15
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
2
0
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
16,790
3
ENSG00000198673
TAFA2
TAFA chemokine like family member 2
[ "Q8N3H0" ]
12
61708273-62279150
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[ "FAM19A2", "TAFA-2" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "No annotated function" ]
null
null
null
null
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 53: Neurons - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 73: Brain - Neuronal signaling
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in all
null
Group enriched
Detected in many
4
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
16,791
9
ENSG00000198674
OR10G6
Olfactory receptor family 10 subfamily G member 6
[ "Q8NH81" ]
11
123994163-123995161
Evidence at transcript level
No human protein/transcript evidence
No human protein/transcript evidence
Evidence at transcript level
[]
[ "OR10G6P", "OR10G6Q" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
null
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,792
7
ENSG00000198677
SKIC3
SKI3 subunit of superkiller complex
[ "Q6PGP7" ]
5
95461755-95555050
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA037905" ]
[ "KIAA0372", "SKI3", "THES", "TTC37" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
31
null
null
Cluster 30: Non-specific - DNA binding
Cluster 26: Oligodendrocytes - Mixed function
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 7: Non-specific - Transcription
Cluster 69: Parathyroid gland - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
16,793
3
ENSG00000198678
OR5BS1P
Olfactory receptor family 5 subfamily BS member 1 pseudogene
[]
12
48559882-48562956
No human protein/transcript evidence
No human protein/transcript evidence
null
null
[]
[ "OR5BS1" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
null
Cluster 4: Breast lactating luminal cells - Lactation
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in single
9
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,794
7
ENSG00000198680
TUSC1
Tumor suppressor candidate 1
[ "Q2TAM9" ]
9
25676969-25678444
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA051426" ]
[ "CCDC89B", "TSG-9" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Approved
null
1
null
null
null
Cluster 27: Non-specific - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Lung Squamous Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
16,795
3
ENSG00000198681
MAGEA1
MAGE family member A1
[ "P43355" ]
X
153179284-153183880
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002620" ]
[ "CT1.1", "MAGE1", "MGC9326" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Tumor antigen" ]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Enhanced
null
39
null
null
null
null
Cluster 51: Myeloma - Immunoglobulins
Cluster 106: Spermatogonia - Spermatogonial differentiation
Cluster 6: Testis - Spermatogenesis
Tissue enriched
Detected in single
44
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in some
32
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,796
2
ENSG00000198682
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
[ "O95340" ]
10
87659613-87747705
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA071224", "HPA075267" ]
[ "ATPSK2" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Kinase", "Multifunctional enzyme", "Nucleotidyltransferase", "Transferase" ]
[ "Disease variant", "Dwarfism" ]
[ "Mitochondria" ]
[]
[]
[]
Approved
Enhanced
null
7
No
No
Cluster 40: Monocytes - Innate immune response
Cluster 47: Endothelial cells - Vasculature
Cluster 64: Connective tissue cells - ECM organization
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 28: Liver & Adrenal gland - Secretion
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
4
2
0
2
[]
[ "Skin Cutaneous Melanoma", "Thyroid Carcinoma" ]
[ "Skin Cutaneous Melanoma", "Thyroid Carcinoma" ]
16,797
5
ENSG00000198689
SLC9A6
Solute carrier family 9 member A6
[ "Q92581" ]
X
135973841-136047269
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA059445", "HPA059590" ]
[ "KIAA0267", "NHE-6", "NHE6" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Antiport", "Ion transport", "Sodium transport", "Transport" ]
[]
[ "Disease variant", "Epilepsy", "Intellectual disability" ]
[ "Vesicles" ]
[ "Plasma membrane" ]
[]
[]
Supported
Enhanced
null
17
null
null
Cluster 33: Non-specific - ATP binding
Cluster 14: Neurons - Synaptic function
Cluster 36: Non-specific - mRNA processing
Cluster 91: Pituicytes/FSC - Homeostasis & neuron support
Cluster 10: Brain - Synaptic signal transduction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
5
Low immune cell specificity
Detected in all
null
3
0
3
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Glioblastoma Multiforme", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
16,798
5
ENSG00000198690
FAN1
FANCD2 and FANCI associated nuclease 1
[ "Q9Y2M0" ]
15
30890559-30943108
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA048198" ]
[ "KIAA1018", "MTMR15" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "DNA damage", "DNA repair" ]
[ "Endonuclease", "Exonuclease", "Hydrolase", "Nuclease" ]
[ "Disease variant" ]
[ "Nucleoplasm", "Cytosol" ]
[ "Cytokinetic bridge", "Primary cilium" ]
[]
[]
Approved
null
null
10
Yes
null
Cluster 16: Non-specific - Cell proliferation
Cluster 45: Non-specific - Mixed function
Cluster 58: Non-specific - Nuclear processes
Cluster 102: Non-specific - Mixed function
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
16,799
8
ENSG00000198691
ABCA4
ATP binding cassette subfamily A member 4
[ "P78363" ]
1
93992834-94121148
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA064420", "HPA078826" ]
[ "ABCR", "ARMD2", "CORD3", "FFM", "RP19", "STGD", "STGD1" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Sensory transduction", "Transport", "Vision" ]
[ "Hydrolase", "Translocase" ]
[ "Age-related macular degeneration", "Cone-rod dystrophy", "Disease variant", "Retinitis pigmentosa", "Stargardt disease" ]
[ "Endoplasmic reticulum" ]
[]
[]
[]
Supported
Enhanced
null
null
null
null
null
Cluster 36: Choroid plexus - Mixed function
Cluster 65: Non-specific - Unknown function
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 42: Retina - Visual perception
Group enriched
Detected in some
31
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
9
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,800
2
ENSG00000198692
EIF1AY
Eukaryotic translation initiation factor 1A Y-linked
[ "O14602" ]
Y
20575776-20593154
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA002561" ]
[]
[ "Predicted intracellular proteins" ]
[ "Protein biosynthesis" ]
[ "Initiation factor", "RNA-binding", "tRNA-binding" ]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Uncertain
Supported
3
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 27: Non-specific - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 52: Non-specific - Cellular respiration
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
16,801
3
ENSG00000198695
MT-ND6
Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6
[ "P03923" ]
MT
14149-14673
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "MTND6", "NAD6", "ND6" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted membrane proteins" ]
[ "Electron transport", "Respiratory chain", "Transport" ]
[ "Translocase" ]
[ "Disease variant", "Dystonia", "Leber hereditary optic neuropathy", "Leigh syndrome", "MELAS syndrome", "Primary mitochondrial disease" ]
[]
[]
[]
[]
null
null
null
1
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 42: Choroid plexus - Mitochondria
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration
Cluster 52: Non-specific - Cellular respiration
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
16,802
7
ENSG00000198700
IPO9
Importin 9
[ "Q96P70" ]
1
201829149-201884291
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA018249", "HPA020866" ]
[ "FLJ10402", "Imp9" ]
[ "Essential proteins", "Predicted intracellular proteins", "Transporters" ]
[ "Protein transport", "Transport" ]
[ "Chaperone" ]
[]
[ "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Supported
null
null
44
null
null
Cluster 25: Non-specific - Unknown function
Cluster 38: Sub-cortical - Mixed function
Cluster 45: Non-specific - Nuclear processes
Cluster 17: Non-specific - RNA processing
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
16,803
7
ENSG00000198704
GPX6
Glutathione peroxidase 6
[ "P59796" ]
6
28503296-28528215
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[]
[ "GPXP3" ]
[ "Enzymes", "Metabolic proteins", "Predicted secreted proteins" ]
[]
[ "Oxidoreductase", "Peroxidase" ]
[]
[]
[]
[ "Secreted in male reproductive system" ]
[ "Enzyme" ]
null
null
null
null
null
null
null
null
Cluster 34: Testis cancer - Unknown function
Cluster 30: Epididymal principal cells - Sperm storage microenvironment
Cluster 22: Epididymis - Mixed function
Tissue enriched
Detected in single
15
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,804
9
ENSG00000198707
CEP290
Centrosomal protein 290
[ "O15078" ]
12
88049016-88142099
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB029995", "HPA043918", "HPA064397" ]
[ "3H11Ag", "BBS14", "CT87", "FLJ13615", "JBTS5", "KIAA0373", "LCA10", "MKS4", "NPHP6", "POC3", "rd16", "SLSN6" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Cilium biogenesis/degradation", "Protein transport", "Transport" ]
[ "Activator" ]
[ "Bardet-Biedl syndrome", "Ciliopathy", "Disease variant", "Intellectual disability", "Joubert syndrome", "Leber congenital amaurosis", "Meckel syndrome", "Nephronophthisis", "Obesity", "Senior-Loken syndrome" ]
[ "Centrosome", "Basal body", "Mid piece" ]
[ "Primary cilium", "Principal piece" ]
[]
[]
Approved
Approved
null
44
null
null
Cluster 24: Non-specific - Transcription
Cluster 9: Non-specific - Receptor signaling
Cluster 38: Non-specific - Transcription
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cell type specificity
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
16,805
1