ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000131475
VPS25
Vacuolar protein sorting 25 homolog
[ "Q9BRG1" ]
17
42773449-42779599
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004978", "HPA021992", "HPA052217", "HPA057284" ]
[ "DERP9", "EAP20", "MGC10540" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Protein transport", "Transcription", "Transcription regulation", "Transport" ]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Supported
Uncertain
null
39
null
Yes
Cluster 29: Non-specific - Unknown function
Cluster 21: Non-specific - Metabolism
Cluster 15: Kidney cancer - Membrane components
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[]
[ "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
6,361
5
ENSG00000131477
RAMP2
Receptor activity modifying protein 2
[ "O60895" ]
17
42758447-42763041
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA052020" ]
[]
[ "FDA approved drug targets", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Transport" ]
[ "Receptor" ]
[ "FDA approved drug targets" ]
[ "Vesicles" ]
[]
[]
[]
Approved
null
null
3
null
null
null
Cluster 42: Choroid plexus - Mitochondria
Cluster 18: Liver cancer - Metabolism
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
5
Immune cell enriched
Detected in single
21
3
2
2
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
6,362
5
ENSG00000131480
AOC2
Amine oxidase copper containing 2
[ "O75106" ]
17
42844580-42850707
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA057779" ]
[ "DAO2", "RAO" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Catecholamine metabolism" ]
[ "Oxidoreductase" ]
[]
[]
[]
[]
[]
null
Uncertain
null
2
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 37: Neurons - Mixed function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 67: Testis - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in some
null
Cell type enriched
Detected in some
4
Immune cell enriched
Detected in single
5
0
0
0
[]
[]
[]
6,363
3
ENSG00000131482
G6PC1
Glucose-6-phosphatase catalytic subunit 1
[ "P35575" ]
17
42900797-42914438
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA052324" ]
[ "G6PC", "G6PT", "GSD1a" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted membrane proteins" ]
[ "Gluconeogenesis" ]
[ "Hydrolase" ]
[ "Disease variant", "Glycogen storage disease" ]
[ "Mid piece" ]
[]
[]
[]
Approved
Enhanced
null
2
null
null
null
Cluster 6: Non-specific - Immune response
Cluster 18: Liver cancer - Metabolism
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 16: Liver & Kidney - Metabolism
Group enriched
Detected in some
6
Cancer enriched
Detected in single
10
Cancer enriched
Detected in some
37
Group enriched
Detected in some
4
Not detected in immune cells
Not detected
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
6,364
8
ENSG00000131495
NDUFA2
NADH:ubiquinone oxidoreductase subunit A2
[ "O43678" ]
5
140638740-140647771
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035933" ]
[ "B8" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Electron transport", "Respiratory chain", "Transport" ]
[]
[ "Primary mitochondrial disease" ]
[ "Mitochondria" ]
[]
[]
[]
Approved
Approved
null
63
null
null
Cluster 29: Non-specific - Unknown function
Cluster 21: Non-specific - Metabolism
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 97: Non-specific - Cellular respiration
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
6,365
2
ENSG00000131503
ANKHD1
Ankyrin repeat and KH domain containing 1
[ "Q8IWZ3" ]
5
140401814-140539856
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA008718" ]
[ "FLJ10042", "FLJ11979", "FLJ14127", "FLJ20288", "KIAA1085", "MASK", "MASK1" ]
[ "Predicted intracellular proteins" ]
[]
[ "RNA-binding" ]
[]
[]
[]
[]
[]
null
Approved
null
21
null
null
Cluster 22: Eosinophils - Transcription
Cluster 50: Non-specific - Nucleic acid binding
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 22: Non-specific - Basic cellular functions
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
5
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
6,366
8
ENSG00000131507
NDFIP1
Nedd4 family interacting protein 1
[ "Q9BT67" ]
5
142108779-142154440
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA009682" ]
[ "MGC10924", "N4WBP5" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "No annotated function" ]
null
Approved
null
11
null
null
Cluster 11: T-cells - Unknown function
Cluster 14: Neurons - Synaptic function
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 65: Brain - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Head and Neck Squamous Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
6,368
3
ENSG00000131558
EXOC4
Exocyst complex component 4
[ "Q96A65" ]
7
133253073-134066589
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA031443" ]
[ "KIAA1699", "MGC27170", "SEC8", "SEC8L1", "Sec8p" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Transporters" ]
[ "Exocytosis", "Protein transport", "Transport" ]
[]
[]
[]
[]
[]
[]
null
Approved
null
68
null
null
Cluster 33: Non-specific - ATP binding
Cluster 23: Choroid plexus - Mixed function
Cluster 39: Non-specific - Transcription
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
6,370
7
ENSG00000131584
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
[ "Q96P50" ]
1
1292390-1309609
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA049317", "HPA058381" ]
[ "CENTB5", "KIAA1716" ]
[ "Predicted intracellular proteins" ]
[]
[ "GTPase activation" ]
[]
[ "Nucleoplasm" ]
[ "Golgi apparatus" ]
[]
[]
Approved
Approved
null
5
null
null
Cluster 25: Non-specific - Unknown function
Cluster 34: Non-specific - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 64: Non-specific - Transcription
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
5
0
5
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma", "Thyroid Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma", "Thyroid Carcinoma" ]
6,371
6
ENSG00000131591
C1orf159
Chromosome 1 open reading frame 159
[ "Q96HA4" ]
1
1081818-1116361
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA010019", "HPA075399" ]
[ "FLJ20584" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Nucleoli rim", "Mitotic chromosome" ]
[ "Intermediate filaments" ]
[]
[]
Approved
Approved
null
null
Yes
No
Cluster 30: Non-specific - DNA binding
Cluster 51: Neurons - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 67: Testis - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
6,372
3
ENSG00000131626
PPFIA1
PTPRF interacting protein alpha 1
[ "Q13136" ]
11
70270690-70385312
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB017032", "HPA042271" ]
[ "LIP.1", "LIPRIN" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Cytosol" ]
[ "Focal adhesion sites" ]
[]
[]
Supported
Uncertain
null
61
null
null
Cluster 20: Non-specific - DNA binding
Cluster 15: Non-specific - Transcription
Cluster 24: Non-specific - Unknown function
Cluster 101: Choroid plexus epithelial cells - Ion transport
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
6,374
1
ENSG00000131634
TMEM204
Transmembrane protein 204
[ "Q9BSN7" ]
16
1528688-1555580
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA014028" ]
[ "C16orf30", "CLP24", "FLJ20898" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Stress response" ]
[]
[]
[]
[]
[]
[]
null
Approved
null
6
null
null
Cluster 11: T-cells - Unknown function
Cluster 47: Endothelial cells - Vasculature
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
4
2
3
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Skin Cutaneous Melanoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Skin Cutaneous Melanoma" ]
6,375
7
ENSG00000131650
KREMEN2
Kringle containing transmembrane protein 2
[ "Q8NCW0" ]
16
2964216-2968383
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA003223" ]
[ "KRM2", "MGC10791" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Wnt signaling pathway" ]
[]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "Other" ]
null
Uncertain
null
null
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 70: Intestinal goblet cells - Mucin production
Cluster 2: Non-specific - Mixed function
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in some
null
1
0
1
[]
[ "Lung Adenocarcinoma" ]
[ "Lung Adenocarcinoma" ]
6,376
7
ENSG00000131652
THOC6
THO complex subunit 6
[ "Q86W42" ]
16
3024027-3027755
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA052953" ]
[ "fSAP35", "MGC2655", "WDR58" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Apoptosis", "mRNA processing", "mRNA splicing", "mRNA transport", "Transport" ]
[ "Developmental protein", "RNA-binding" ]
[ "Disease variant", "Intellectual disability" ]
[ "Nucleoplasm", "Nuclear speckles" ]
[]
[]
[]
Supported
Uncertain
null
18
No
No
Cluster 13: Non-specific - Mitochondria
Cluster 49: Hindbrain - Mixed function
Cluster 54: Non-specific - Transcription
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
6,377
9
ENSG00000131653
TRAF7
TNF receptor associated factor 7
[ "Q6Q0C0" ]
16
2155698-2178129
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA040935", "HPA041229" ]
[ "DKFZp586I021", "MGC7807", "RFWD1", "RNF119" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Apoptosis", "Transcription", "Transcription regulation", "Ubl conjugation pathway" ]
[ "Transferase" ]
[ "Cancer-related genes", "Disease variant" ]
[ "Vesicles" ]
[]
[]
[]
Supported
Approved
null
36
null
null
Cluster 33: Non-specific - ATP binding
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 54: Non-specific - Transcription
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
6,378
9
ENSG00000131668
BARX1
BARX homeobox 1
[ "Q9HBU1" ]
9
93951627-93955355
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA055858" ]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Approved
null
null
null
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 62: Smooth muscle cells - Muscle contraction
Cluster 60: Stomach - Digestion
Tissue enriched
Detected in some
10
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Head and Neck Squamous Cell Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
6,379
8
ENSG00000131669
NINJ1
Ninjurin 1
[ "Q92982" ]
9
93121496-93134251
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA045063" ]
[ "NIN1" ]
[ "Predicted membrane proteins" ]
[ "Angiogenesis", "Cell adhesion", "Cytolysis", "Inflammatory response" ]
[]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "Cell adhesion" ]
null
Uncertain
null
16
null
null
Cluster 7: Non-specific - Innate immune response
Cluster 44: Non-specific - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 15: Bone marrow - Innate immune response
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
1
0
1
[ "Thyroid Carcinoma" ]
[]
[ "Thyroid Carcinoma" ]
6,380
8
ENSG00000131686
CA6
Carbonic anhydrase 6
[ "P23280" ]
1
8945867-8975092
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA028550", "HPA028692" ]
[]
[ "Enzymes", "FDA approved drug targets", "Metabolic proteins", "Predicted secreted proteins" ]
[]
[ "Lyase" ]
[ "FDA approved drug targets" ]
[]
[]
[ "Secreted to digestive system" ]
[ "Enzyme" ]
null
Enhanced
null
35
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 6: Non-specific - Immune response
Cluster 70: DU4475 - Unknown function
Cluster 38: Secretory epithelial cells - Exocrine secretion
Cluster 82: Salivary gland - Secretion
Tissue enriched
Detected in some
290
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in some
null
Group enriched
Detected in some
4
0
0
0
[]
[]
[]
6,381
7
ENSG00000131697
NPHP4
Nephrocystin 4
[ "O75161" ]
1
5862811-5992473
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA063852", "HPA065526" ]
[ "KIAA0673", "POC10", "SLSN4" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[ "Ciliopathy", "Disease variant", "Leber congenital amaurosis", "Nephronophthisis", "Senior-Loken syndrome" ]
[ "Nucleoplasm" ]
[ "Nuclear bodies", "Vesicles", "Cytosol" ]
[]
[]
Approved
Approved
null
23
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
Cluster 21: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
6,382
1
ENSG00000131711
MAP1B
Microtubule associated protein 1B
[ "P46821" ]
5
72107234-72209565
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB009792", "HPA022275" ]
[ "MAP5", "PPP1R102" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[ "Deafness", "Disease variant", "Non-syndromic deafness" ]
[ "Cytosol" ]
[ "Equatorial segment" ]
[]
[]
Supported
Enhanced
Supported
64
null
null
null
Cluster 45: Non-specific - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 110: Mural cells - ECM organization
Cluster 46: Brain & retina - Neuronal signaling
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
6,383
9
ENSG00000131721
RHOXF2
Rhox homeobox family member 2
[ "Q9BQY4" ]
X
120158613-120165630
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003314", "CAB020794" ]
[ "CT107", "PEPP-2", "PEPP2", "THG1" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[]
[ "DNA-binding" ]
[]
[ "Plasma membrane" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Enhanced
null
70
null
null
null
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 51: Myeloma - Immunoglobulins
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 57: Testis - Spermatogenesis
Tissue enriched
Detected in single
15
Group enriched
Detected in some
4
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
6,384
6
ENSG00000131724
IL13RA1
Interleukin 13 receptor subunit alpha 1
[ "P78552" ]
X
118727133-118794535
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "CD213a1", "IL-13Ra", "NR4" ]
[ "CD markers", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[]
[ "Receptor" ]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "Receptor" ]
null
null
null
8
null
null
Cluster 7: Non-specific - Innate immune response
Cluster 44: Non-specific - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 45: Liver - Metabolism & Coagulation
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
6
1
0
1
[]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe" ]
6,385
3
ENSG00000131725
WDR44
WD repeat domain 44
[ "Q5JSH3" ]
X
118346073-118449961
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038084", "HPA046719" ]
[ "DKFZp686L20145", "RAB11BP", "RPH11", "SYM-4" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Golgi apparatus" ]
[]
[]
[]
Supported
Approved
null
21
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 13: Oligodendrocytes - Mixed function
Cluster 36: Non-specific - mRNA processing
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
6,386
1
ENSG00000131730
CKMT2
Creatine kinase, mitochondrial 2
[ "P17540" ]
5
81233320-81266398
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA051880" ]
[ "SMTCK" ]
[ "Enzymes", "FDA approved drug targets", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Kinase", "Transferase" ]
[ "FDA approved drug targets" ]
[]
[]
[]
[]
null
Enhanced
null
31
null
null
null
Cluster 47: Endothelial cells - Vasculature
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 55: Myocytes - Oxidative muscle function
Cluster 41: Striated muscle - Muscle contraction
Group enriched
Detected in many
28
Cancer enhanced
Detected in many
null
Cancer enriched
Detected in many
10
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
7
3
0
3
[ "Lung Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Chromophobe" ]
[ "Glioblastoma Multiforme", "Kidney Chromophobe", "Lung Adenocarcinoma" ]
6,387
7
ENSG00000131732
ZCCHC9
Zinc finger CCHC-type containing 9
[ "Q8N567" ]
5
81301587-81313297
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038404" ]
[ "DKFZp761J139", "PPP1R41" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Transcription" ]
[]
[]
[ "Nucleoplasm" ]
[ "Nucleoli" ]
[]
[]
Supported
Uncertain
null
9
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 25: Non-specific - Transcription
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 97: Non-specific - Cellular respiration
Cluster 31: Liver - Metabolism & Coagulation
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Lung Adenocarcinoma" ]
[ "Lung Adenocarcinoma" ]
6,388
4
ENSG00000131737
KRT34
Keratin 34
[ "O76011" ]
17
41377669-41382306
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA055194", "HPA072208" ]
[ "Ha-4", "KRTHA4" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol", "Principal piece", "End piece" ]
[ "Equatorial segment", "Mid piece" ]
[]
[]
Approved
Enhanced
null
211
null
null
null
null
Cluster 64: Connective tissue cells - ECM organization
Cluster 73: Late spermatids - Spermiogenesis: Maturation
Cluster 9: Skin - Hair follicle development
Tissue enriched
Detected in some
22
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in single
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
6,389
3
ENSG00000131746
TNS4
Tensin 4
[ "Q8IZW8" ]
17
40475828-40501623
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA024388", "HPA079528" ]
[ "CTEN" ]
[ "Predicted intracellular proteins" ]
[]
[ "Actin-binding" ]
[]
[ "Cytosol" ]
[]
[]
[]
Enhanced
null
null
24
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 26: Keratinocytes - Keratinization
Cluster 58: Skin - Keratinization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Lung Adenocarcinoma" ]
[ "Lung Adenocarcinoma" ]
6,391
6
ENSG00000131747
TOP2A
DNA topoisomerase II alpha
[ "P11388" ]
17
40388525-40417896
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002448", "HPA006458", "HPA026773" ]
[ "TOP2", "TOP2alpha", "TOPIIA" ]
[ "Cancer-related genes", "Enzymes", "Essential proteins", "FDA approved drug targets", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Biological rhythms" ]
[ "DNA-binding", "Isomerase", "Topoisomerase" ]
[ "Cancer-related genes", "FDA approved drug targets" ]
[ "Nucleoplasm" ]
[ "Nucleoli" ]
[]
[]
Supported
Enhanced
Approved
235
Yes
Yes
Cluster 9: T-regs - Cell cycle regulation
Cluster 12: Non-specific - Vasculature
Cluster 30: Non-specific - Gene expression regulation
Cluster 27: Non-specific - Cell proliferation
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
6
4
4
[ "Rectum Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Rectum Adenocarcinoma" ]
6,392
1
ENSG00000131748
STARD3
StAR related lipid transfer domain containing 3
[ "Q14849" ]
17
39637090-39664201
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB017021", "HPA024307", "HPA073948" ]
[ "es64", "MLN64" ]
[ "Cancer-related genes", "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Lipid transport", "Transport" ]
[]
[ "Cancer-related genes" ]
[ "Nucleoplasm", "Vesicles" ]
[ "Endoplasmic reticulum" ]
[]
[]
Approved
Uncertain
null
31
null
null
Cluster 7: Non-specific - Innate immune response
Cluster 38: Sub-cortical - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
6,393
3
ENSG00000131759
RARA
Retinoic acid receptor alpha
[ "P10276" ]
17
40309180-40357643
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA058282", "HPA071548" ]
[ "NR1B1", "RAR", "RAR-alpha", "RARalpha" ]
[ "Cancer-related genes", "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Nuclear receptors", "Plasma proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Receptor" ]
[ "Cancer-related genes", "FDA approved drug targets", "Proto-oncogene" ]
[ "Nucleoplasm" ]
[ "Nucleoli", "Actin filaments", "Cytosol" ]
[]
[]
Supported
null
null
104
null
null
Cluster 7: Non-specific - Innate immune response
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 27: Breast cancer - Unknown function
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
6,394
8
ENSG00000131771
PPP1R1B
Protein phosphatase 1 regulatory inhibitor subunit 1B
[ "Q9UD71" ]
17
39626740-39636626
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB004026", "HPA048630", "HPA061142" ]
[ "DARPP-32", "FLJ20940" ]
[ "Predicted intracellular proteins" ]
[]
[ "Protein phosphatase inhibitor" ]
[]
[]
[]
[]
[]
null
Approved
Approved
2
null
null
Cluster 19: Eosinophils - Unknown function
Cluster 33: Neurons - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration
Cluster 1: Choroid plexus - Transmembrane transport
Group enriched
Detected in many
4
Group enriched
Detected in many
7
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
11
2
0
2
[ "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
6,395
7
ENSG00000131773
KHDRBS3
KH RNA binding domain containing, signal transduction associated 3
[ "O75525" ]
8
135457456-135656722
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000275", "HPA000500", "HPA000981" ]
[ "Etle", "etoile", "SALP", "SLM-2", "SLM2", "T-STAR" ]
[ "Predicted intracellular proteins" ]
[ "Host-virus interaction", "mRNA processing", "Transcription", "Transcription regulation" ]
[ "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Enhanced
null
55
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 69: Skin cancer - ECM organization
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 67: Testis - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
13
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
6,396
8
ENSG00000131778
CHD1L
Chromodomain helicase DNA binding protein 1 like
[ "Q86WJ1" ]
1
147242654-147295765
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA027789", "HPA027790", "HPA028670" ]
[ "ALC1" ]
[ "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair" ]
[ "Hydrolase" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Enhanced
null
21
null
null
Cluster 41: Basophils - Unknown function
Cluster 28: Oligodendrocytes - Mixed function
Cluster 45: Non-specific - Nuclear processes
Cluster 102: Non-specific - Mixed function
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Breast Invasive Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
6,397
8
ENSG00000131779
PEX11B
Peroxisomal biogenesis factor 11 beta
[ "O96011" ]
1
145911350-145918717
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA017150", "HPA050104" ]
[ "PEX11beta" ]
[ "Disease related genes", "Human disease related genes", "Predicted membrane proteins" ]
[ "Peroxisome biogenesis" ]
[]
[ "Peroxisome biogenesis disorder" ]
[ "Vesicles" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Supported
null
3
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 14: Neurons - Synaptic function
Cluster 45: Non-specific - Nuclear processes
Cluster 97: Non-specific - Cellular respiration
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
6,398
3
ENSG00000131781
FMO5
Flavin containing dimethylaniline monoxygenase 5
[ "P49326" ]
1
147175351-147243050
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA012373" ]
[]
[ "Cancer-related genes", "Enzymes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Lipid metabolism" ]
[ "Monooxygenase", "Oxidoreductase" ]
[ "Cancer-related genes" ]
[ "Endoplasmic reticulum", "Cytosol" ]
[]
[]
[]
Supported
Enhanced
null
null
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 30: White matter - Myelination
Cluster 18: Liver cancer - Metabolism
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 45: Liver - Metabolism & Coagulation
Tissue enriched
Detected in many
5
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
5
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Rectum Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Rectum Adenocarcinoma" ]
6,399
2
ENSG00000131791
PRKAB2
Protein kinase AMP-activated non-catalytic subunit beta 2
[ "O43741" ]
1
147155106-147172550
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044342" ]
[]
[ "FDA approved drug targets", "Predicted intracellular proteins" ]
[ "Fatty acid biosynthesis", "Fatty acid metabolism", "Lipid biosynthesis", "Lipid metabolism" ]
[]
[ "FDA approved drug targets" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
221
null
null
Cluster 41: Basophils - Unknown function
Cluster 37: Neurons - Mixed function
Cluster 45: Non-specific - Nuclear processes
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in single
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Thyroid Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Thyroid Carcinoma" ]
6,401
1
ENSG00000131808
FSHB
Follicle stimulating hormone subunit beta
[ "P01225" ]
11
30231014-30235261
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB023410", "HPA069703" ]
[]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted secreted proteins" ]
[]
[ "Hormone" ]
[ "Cancer-related genes", "Disease variant", "Hypogonadotropic hypogonadism" ]
[]
[]
[ "Secreted to blood" ]
[ "Hormone" ]
null
Enhanced
null
1
null
null
null
Cluster 51: Neurons - Mixed function
null
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 20: Pituitary gland - Hormone signaling
Tissue enriched
Detected in single
271
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
76
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
6,402
3
ENSG00000131828
PDHA1
Pyruvate dehydrogenase E1 subunit alpha 1
[ "P08559" ]
X
19343893-19361718
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047487", "HPA047864", "HPA063053" ]
[ "E1alpha", "PDHA" ]
[ "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Carbohydrate metabolism", "Glucose metabolism", "Tricarboxylic acid cycle" ]
[ "Oxidoreductase" ]
[ "Disease variant", "Leigh syndrome", "Primary mitochondrial disease" ]
[ "Mitochondria" ]
[]
[]
[]
Supported
Approved
null
112
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 14: Neurons - Synaptic function
Cluster 36: Non-specific - mRNA processing
Cluster 97: Non-specific - Cellular respiration
Cluster 41: Striated muscle - Muscle contraction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
6,403
8
ENSG00000131831
RAI2
Retinoic acid induced 2
[ "Q9Y5P3" ]
X
17800049-17861337
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA051054" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Plasma membrane" ]
[]
[]
[]
Approved
Uncertain
null
20
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 5: Rhabdoid - Unknown function
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma", "Rectum Adenocarcinoma" ]
6,404
4
ENSG00000131844
MCCC2
Methylcrotonyl-CoA carboxylase subunit 2
[ "Q9HCC0" ]
5
71579531-71658706
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038300", "HPA038301", "HPA061546" ]
[ "MCCB", "MCCCbeta" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Ligase" ]
[ "Disease variant" ]
[ "Mitochondria" ]
[]
[]
[]
Enhanced
Enhanced
null
14
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 21: Non-specific - Metabolism
Cluster 60: Prostate cancer - Unknown function
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
6,405
8
ENSG00000131845
ZNF304
Zinc finger protein 304
[ "Q9HCX3" ]
19
57351271-57359898
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA050531" ]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Angiogenesis", "Transcription", "Transcription regulation" ]
[ "Activator", "Chromatin regulator", "DNA-binding" ]
[]
[ "Nuclear speckles" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
null
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 31: Non-specific - Transcription
Cluster 4: Non-specific - Transcription
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
6,406
8
ENSG00000131848
ZSCAN5A
Zinc finger and SCAN domain containing 5A
[ "Q9BUG6" ]
19
56219670-56368383
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041263", "HPA043123", "HPA046836", "HPA060667" ]
[ "MGC4161", "ZNF495", "ZSCAN5" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nuclear speckles" ]
[]
[]
[]
Uncertain
Uncertain
null
21
null
null
Cluster 29: Non-specific - Unknown function
Cluster 42: Choroid plexus - Mitochondria
Cluster 4: Non-specific - Transcription
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 56: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
6,407
2
ENSG00000131849
ZNF132
Zinc finger protein 132
[ "P52740" ]
19
58432814-58440153
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA008726" ]
[ "pHZ-12" ]
[ "Cancer-related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[ "Cancer-related genes" ]
[ "Vesicles" ]
[ "Intermediate filaments" ]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 2: Neurons - Nucleosome
Cluster 4: Non-specific - Transcription
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 69: Parathyroid gland - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
6,408
2
ENSG00000131864
USP29
Ubiquitin specific peptidase 29
[ "Q9HBJ7" ]
19
57119138-57131926
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
[ "HPA076515" ]
[]
[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Immunity", "Innate immunity", "Ubl conjugation pathway" ]
[ "Hydrolase", "Protease", "Thiol protease" ]
[]
[ "Plasma membrane" ]
[ "Cytosol" ]
[]
[]
Supported
Enhanced
null
6
null
null
Cluster 20: Non-specific - DNA binding
Cluster 25: Non-specific - Transcription
Cluster 56: Non-specific - Sensory perception
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 39: Testis - Nuclear processes
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in single
null
0
0
0
[]
[]
[]
6,409
9
ENSG00000131871
SELENOS
Selenoprotein S
[ "Q9BQE4" ]
15
101270817-101277500
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA010025" ]
[ "AD-015", "MGC2553", "SBBI8", "SELS", "SEPS1", "VIMP" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Endoplasmic reticulum" ]
[]
[]
[]
Enhanced
Approved
null
16
null
null
Cluster 29: Non-specific - Unknown function
Cluster 21: Non-specific - Metabolism
Cluster 63: Non-specific - Protein processing
Cluster 67: Plasma cells - Plasma cell differentiation
Cluster 21: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Immune cell enriched
Detected in all
5
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
6,410
2
ENSG00000131873
CHSY1
Chondroitin sulfate synthase 1
[ "Q86X52" ]
15
101175727-101252048
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "CSS1", "KIAA0990" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Transferase" ]
[ "Disease variant" ]
[]
[]
[ "Secreted to blood" ]
[ "Enzyme" ]
null
null
null
2
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 12: Non-specific - Vasculature
Cluster 71: Lymphoma - Inflammatory response
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Thyroid Carcinoma" ]
[ "Thyroid Carcinoma" ]
6,411
4
ENSG00000131876
SNRPA1
Small nuclear ribonucleoprotein polypeptide A'
[ "P09661" ]
15
101281510-101295282
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA045622", "HPA048499" ]
[ "Lea1", "U2A'" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing" ]
[ "Ribonucleoprotein", "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Nuclear speckles", "Nuclear bodies" ]
[]
[]
Supported
Supported
null
168
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 31: Non-specific - Transcription
Cluster 58: Non-specific - Nuclear processes
Cluster 17: Non-specific - RNA processing
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
4
2
3
[]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
6,412
6
ENSG00000131899
LLGL1
LLGL scribble cell polarity complex component 1
[ "Q15334" ]
17
18225635-18244875
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA022924" ]
[ "DLG4", "HUGL", "HUGL-1", "Lgl1", "LLGL", "Mgl1" ]
[ "Predicted intracellular proteins" ]
[ "Exocytosis" ]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
35
null
null
null
Cluster 13: Oligodendrocytes - Mixed function
Cluster 42: Non-specific - Unknown function
Cluster 80: Oligodendrocytes - Myelination
Cluster 3: Oligodendrocytes - Myelination
Tissue enriched
Detected in all
4
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
6,413
9
ENSG00000131910
NR0B2
Nuclear receptor subfamily 0 group B member 2
[ "Q15466" ]
1
26911489-26913975
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003983" ]
[ "SHP" ]
[ "Disease related genes", "Human disease related genes", "Nuclear receptors", "Predicted intracellular proteins", "Transcription factors" ]
[ "Biological rhythms", "Transcription", "Transcription regulation" ]
[ "Receptor", "Repressor" ]
[ "Disease variant", "Obesity" ]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Supported
null
null
40
null
null
null
null
Cluster 10: Ciliated cells - Ion channel activity
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 26: Kidney & Intestine - Metabolism
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Group enriched
Detected in many
4
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
6,414
4
ENSG00000131914
LIN28A
Lin-28 homolog A
[ "Q9H9Z2" ]
1
26410817-26429728
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB020785", "HPA063074", "HPA068814" ]
[ "CSDD1", "FLJ12457", "LIN-28", "LIN28", "ZCCHC1" ]
[ "Predicted intracellular proteins" ]
[ "RNA-mediated gene silencing" ]
[ "RNA-binding" ]
[]
[ "Cytosol" ]
[ "Nucleoli", "Rods & Rings" ]
[]
[]
Supported
Enhanced
null
250
null
null
null
Cluster 48: Non-specific - Mixed function
Cluster 34: Testis cancer - Unknown function
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 79: Testis - Spermatogenesis
Tissue enriched
Detected in single
14
Cancer enriched
Detected in many
10
Cancer enriched
Detected in some
85
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
6,415
3
ENSG00000131931
THAP1
THAP domain containing 1
[ "Q9NVV9" ]
8
42836674-42843325
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA071310" ]
[ "4833431A01Rik", "DYT6", "FLJ10477" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Cell cycle", "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[ "Disease variant", "Dystonia" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
null
null
93
No
No
Cluster 5: Non-specific - Cell proliferation
Cluster 31: Non-specific - Transcription
Cluster 40: Non-specific - Unknown function
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
6,416
4
ENSG00000131943
C19orf12
Chromosome 19 open reading frame 12
[ "Q9NSK7" ]
19
29698937-29715789
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046930" ]
[ "DKFZP762D096", "MGC10922", "MPAN", "NBIA4", "SPG43" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant", "Hereditary spastic paraplegia", "Neurodegeneration" ]
[ "Cytosol" ]
[]
[]
[]
Supported
Approved
null
null
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 1: Neurons - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 89: Adipocytes - Lipid metabolism
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
6,418
1
ENSG00000131944
FAAP24
FA core complex associated protein 24
[ "Q9BTP7" ]
19
32972209-32978229
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041168" ]
[ "C19orf40", "FLJ46828", "MGC32020" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Supported
Uncertain
null
8
null
null
Cluster 25: Non-specific - Unknown function
Cluster 11: White matter - Signal transduction
Cluster 4: Non-specific - Transcription
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
6,419
1
ENSG00000131951
LRRC9
Leucine rich repeat containing 9
[ "Q6ZRR7" ]
14
59919713-60066817
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA040965", "HPA041381", "HPA077675" ]
[ "FLJ46156" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Plasma membrane", "Cell Junctions" ]
[ "Nucleoplasm", "Nuclear bodies" ]
[]
[]
Approved
Uncertain
null
null
null
null
null
Cluster 3: Choroid plexus - Cilium
Cluster 10: Ciliated cells - Ion channel activity
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 56: Ciliated tissues - Cilium organization
Group enriched
Detected in some
5
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
6,420
2
ENSG00000131966
ACTR10
Actin related protein 10
[ "Q9NZ32" ]
14
58200080-58235636
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA000699" ]
[ "ACTR11", "Arp10", "Arp11", "HARP11" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles", "Plasma membrane" ]
[ "Focal adhesion sites", "Perinuclear theca", "Connecting piece", "Flagellar centriole", "Mid piece", "Principal piece" ]
[]
[]
Approved
null
null
38
null
null
Cluster 32: Basophils - Transcription
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 30: Non-specific - Gene expression regulation
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Cancer enriched
Detected in all
8
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Pancreatic Adenocarcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
6,421
9
ENSG00000131969
ABHD12B
Abhydrolase domain containing 12B
[ "Q7Z5M8" ]
14
50872053-50904970
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA002873" ]
[ "BEM46L3", "C14orf29" ]
[ "Predicted intracellular proteins" ]
[]
[ "Hydrolase" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Uncertain
Uncertain
null
null
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 38: Sub-cortical - Mixed function
Cluster 32: Non-specific - Cell proliferation
Cluster 11: Muller glia cells - Retinal homeostasis
Cluster 46: Brain & retina - Neuronal signaling
Group enriched
Detected in some
7
Cancer enriched
Detected in some
5
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
4
0
0
0
[]
[]
[]
6,422
6
ENSG00000131979
GCH1
GTP cyclohydrolase 1
[ "P30793" ]
14
54842008-54902826
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA028612" ]
[ "DYT14", "DYT5", "DYT5a", "GCH", "GTPCH1" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Tetrahydrobiopterin biosynthesis" ]
[ "Allosteric enzyme", "Hydrolase" ]
[ "Disease variant", "Dystonia", "Parkinsonism", "Phenylketonuria" ]
[ "Nucleoplasm" ]
[ "Nuclear membrane", "Cytosol" ]
[]
[]
Supported
Approved
null
11
No
No
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 10: Ciliated cells - Ion channel activity
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 31: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
0
2
[ "Pancreatic Adenocarcinoma" ]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
6,423
2
ENSG00000132000
PODNL1
Podocan like 1
[ "Q6PEZ8" ]
19
13931187-13953392
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA042807" ]
[ "FLJ23447", "SLRR5B" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted - unknown location" ]
[ "No annotated function" ]
null
Approved
null
null
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 5: Rhabdoid - Unknown function
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 74: Non-specific - Signal transduction
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
3
0
3
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
6,425
1
ENSG00000132002
DNAJB1
DnaJ heat shock protein family (Hsp40) member B1
[ "P25685" ]
19
14514769-14560391
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB017450", "HPA063247" ]
[ "Hsp40", "HSPF1", "RSPH16B", "Sis1" ]
[ "Cancer-related genes", "Predicted intracellular proteins" ]
[ "Stress response" ]
[ "Chaperone" ]
[ "Cancer-related genes" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Enhanced
null
106
null
Yes
Cluster 31: T-cells - T-cell receptor
Cluster 55: Non-specific - Transcription
Cluster 23: Non-specific - Transcription
Cluster 75: Non-specific - Chaperones and protein folding
Cluster 81: Squamous epithelium - Keratinization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
6,426
8
ENSG00000132003
ZSWIM4
Zinc finger SWIM-type containing 4
[ "Q9H7M6" ]
19
13795443-13832254
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA042084" ]
[ "FLJ12221" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
Cluster 18: Non-specific - Mixed function
Cluster 23: Non-specific - Transcription
Cluster 105: Non-specific - Mixed function
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
3
0
4
[ "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Rectum Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Rectum Adenocarcinoma" ]
6,427
7
ENSG00000132004
FBXW9
F-box and WD repeat domain containing 9
[ "Q5XUX1" ]
19
12688053-12696631
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA042087" ]
[ "Fbw9", "MEC-15", "MGC10870" ]
[ "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Approved
null
5
null
null
Cluster 33: Non-specific - ATP binding
Cluster 17: Choroid plexus - Cilium
Cluster 23: Non-specific - Transcription
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Rectum Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Skin Cutaneous Melanoma" ]
[ "Liver Hepatocellular Carcinoma", "Rectum Adenocarcinoma", "Skin Cutaneous Melanoma" ]
6,428
1
ENSG00000132005
RFX1
Regulatory factor X1
[ "P22670" ]
19
13961530-14007039
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA048722", "HPA052966" ]
[ "EF-C" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Enhanced
Approved
null
23
null
null
Cluster 20: Non-specific - DNA binding
Cluster 15: Non-specific - Transcription
Cluster 23: Non-specific - Transcription
Cluster 102: Non-specific - Mixed function
Cluster 67: Testis - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
3
0
3
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
6,429
3
ENSG00000132010
ZNF20
Zinc finger protein 20
[ "P17024" ]
19
12092843-12140355
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA020887", "HPA073206" ]
[ "KOX13" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nuclear membrane" ]
[ "Nucleoplasm", "Nuclear bodies" ]
[]
[]
Approved
Uncertain
null
43
null
null
Cluster 7: Non-specific - Innate immune response
Cluster 50: Non-specific - Nucleic acid binding
Cluster 4: Non-specific - Transcription
Cluster 90: Elongating spermatids - Spermiogenesis: Elongation
Cluster 56: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Head and Neck Squamous Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Chromophobe" ]
6,430
9
ENSG00000132016
BRME1
Break repair meiotic recombinase recruitment factor 1
[ "Q0VDD7" ]
19
13882348-13906452
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044012", "HPA054615" ]
[ "C19orf57", "MEIOK21", "MGC11271" ]
[ "Predicted intracellular proteins" ]
[ "Meiosis" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Enhanced
null
26
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 37: Neurons - Mixed function
Cluster 70: DU4475 - Unknown function
Cluster 3: Early primary spermatocytes - Early meiosis
Cluster 67: Testis - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Head and Neck Squamous Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Chromophobe" ]
6,431
3
ENSG00000132024
CC2D1A
Coiled-coil and C2 domain containing 1A
[ "Q6P1N0" ]
19
13906201-13930879
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA005436", "CAB015220" ]
[ "Aki-1", "FLJ20241", "Freud-1", "Lgd2", "MRT3", "TAPE" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Repressor" ]
[ "Intellectual disability" ]
[ "Cytosol" ]
[ "Nucleoli fibrillar center", "Plasma membrane", "Basal body" ]
[]
[]
Supported
Supported
null
10
null
null
Cluster 25: Non-specific - Unknown function
Cluster 1: Neurons - Mixed function
Cluster 23: Non-specific - Transcription
Cluster 102: Non-specific - Mixed function
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
6,433
2
ENSG00000132031
MATN3
Matrilin 3
[ "O15232" ]
2
19992052-20012668
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA051250", "HPA074980" ]
[ "EDM5", "HOA" ]
[ "Disease related genes", "Human disease related genes", "Predicted secreted proteins" ]
[]
[]
[ "Disease variant", "Dwarfism" ]
[ "Endoplasmic reticulum", "Golgi apparatus", "Vesicles" ]
[]
[ "Secreted to extracellular matrix" ]
[ "No annotated function" ]
Approved
null
null
5
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 18: Liver cancer - Metabolism
Cluster 110: Mural cells - ECM organization
Cluster 43: Placenta - Pregnancy hormone signaling
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
3
0
3
[]
[ "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma", "Stomach Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma", "Stomach Adenocarcinoma" ]
6,435
8
ENSG00000132109
TRIM21
Tripartite motif containing 21
[ "P19474" ]
11
4384897-4393702
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004566", "HPA005673" ]
[ "RNF81", "RO52", "SSA1" ]
[ "Enzymes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "Host-virus interaction", "Ubl conjugation pathway" ]
[ "DNA-binding", "Ribonucleoprotein", "RNA-binding", "Transferase" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Enhanced
null
134
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 43: Hindbrain - Mixed function
Cluster 31: Non-specific - Antiviral immune response
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 66: Lymphoid tissue - Immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
4
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Thyroid Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Thyroid Carcinoma" ]
6,436
1
ENSG00000132122
SPATA6
Spermatogenesis associated 6
[ "Q9NWH7" ]
1
48295373-48472208
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA028234" ]
[ "FLJ10007", "SRF-1", "SRF1" ]
[ "Cancer-related genes", "Predicted intracellular proteins" ]
[ "Differentiation", "Spermatogenesis" ]
[ "Developmental protein" ]
[ "Cancer-related genes" ]
[ "Golgi apparatus", "Vesicles" ]
[ "Nucleoplasm" ]
[ "Intracellular and membrane" ]
[ "Developmental protein" ]
Approved
null
null
1
null
null
Cluster 25: Non-specific - Unknown function
Cluster 11: White matter - Signal transduction
Cluster 69: Skin cancer - ECM organization
Cluster 73: Late spermatids - Spermiogenesis: Maturation
Cluster 21: Testis - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enriched
Detected in many
4
Immune cell enhanced
Detected in some
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
6,437
7
ENSG00000132128
LRRC41
Leucine rich repeat containing 41
[ "Q15345" ]
1
46261196-46303616
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA051941" ]
[ "MUF1" ]
[ "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[]
[]
[ "Nuclear bodies" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Uncertain
null
17
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 27: Non-specific - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
6,438
6
ENSG00000132141
CCT6B
Chaperonin containing TCP1 subunit 6B
[ "Q92526" ]
17
34927859-34981078
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042996", "HPA045576", "HPA049949" ]
[ "Cctz2", "TSA303" ]
[ "Predicted intracellular proteins" ]
[]
[ "Chaperone" ]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
82
null
null
Cluster 14: Non-specific - Unknown function
Cluster 28: Oligodendrocytes - Mixed function
Cluster 67: Non-specific - Unknown function
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 57: Testis - Spermatogenesis
Tissue enriched
Detected in many
23
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
6,439
1
ENSG00000132153
DHX30
DExH-box helicase 30
[ "Q7L2E3" ]
3
47802909-47850195
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA034806" ]
[ "DDX30", "FLJ11214", "KIAA0890" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Ribosome biogenesis" ]
[ "Helicase", "Hydrolase", "RNA-binding" ]
[ "Disease variant", "Intellectual disability" ]
[ "Mitochondria" ]
[ "Cytosol" ]
[]
[]
Supported
Supported
null
89
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 14: Neurons - Synaptic function
Cluster 8: Non-specific - Basic cellular processes
Cluster 10: Epididymal principal cells - Sperm maturation microenvironment
Cluster 67: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
2
0
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
6,440
8
ENSG00000132155
RAF1
Raf-1 proto-oncogene, serine/threonine kinase
[ "P04049" ]
3
12582101-12664201
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA002639", "HPA002640", "CAB019291", "CAB080384" ]
[ "c-Raf", "CRAF", "Raf-1" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Predicted intracellular proteins", "RAS pathway related proteins" ]
[]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[ "Cancer-related genes", "Cardiomyopathy", "Deafness", "Disease variant", "FDA approved drug targets", "Proto-oncogene" ]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Supported
Approved
null
284
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 25: Non-specific - Transcription
Cluster 8: Non-specific - Basic cellular processes
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 63: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Immune cell enhanced
Detected in all
null
3
0
3
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Glioblastoma Multiforme", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
6,441
6
ENSG00000132164
SLC6A11
Solute carrier family 6 member 11
[ "P48066" ]
3
10816201-10940714
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA037981" ]
[ "GAT3" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Neurotransmitter transport", "Symport", "Transport" ]
[]
[]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Uncertain
Supported
Supported
null
null
null
null
Cluster 19: Astrocytes - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 28: Astrocytes - Homeostasis & neuron support
Cluster 3: Oligodendrocytes - Myelination
Tissue enriched
Detected in some
8
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
6,442
4
ENSG00000132170
PPARG
Peroxisome proliferator activated receptor gamma
[ "P37231" ]
3
12287368-12434356
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004282", "HPA051239", "HPA063663" ]
[ "NR1C3", "PPARG1", "PPARG2", "PPARgamma" ]
[ "Cancer-related genes", "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Nuclear receptors", "Plasma proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Biological rhythms", "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding", "Receptor" ]
[ "Cancer-related genes", "Diabetes mellitus", "Disease variant", "FDA approved drug targets", "Obesity" ]
[ "Nucleoplasm", "Vesicles" ]
[]
[]
[]
Enhanced
Approved
null
99
null
null
null
Cluster 37: Neurons - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
4
1
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
6,443
8
ENSG00000132182
NUP210
Nucleoporin 210
[ "Q8TEM1" ]
3
13316235-13420322
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA066888" ]
[ "FLJ22389", "GP210", "KIAA0906", "POM210" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "mRNA transport", "Protein transport", "Translocation", "Transport" ]
[]
[]
[]
[]
[]
[]
null
Approved
null
25
null
null
Cluster 30: Non-specific - DNA binding
Cluster 25: Non-specific - Transcription
Cluster 8: Non-specific - Basic cellular processes
Cluster 102: Non-specific - Mixed function
Cluster 51: Lymphoid tissue - Adaptive immune response
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
6,444
3
ENSG00000132185
FCRLA
Fc receptor like A
[ "Q7L513" ]
1
161706972-161714352
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB016545" ]
[ "FCRL", "FCRLb", "FCRLc1", "FCRLc2", "FCRLd", "FCRLe", "FCRLM1", "FCRLX", "FREB", "MGC4595" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation" ]
[]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "Other" ]
null
Enhanced
null
null
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 46: Lymphoma - Humoral immune response
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 18: Lymphoid tissue - Immune response
Tissue enriched
Detected in some
5
Cancer enriched
Detected in some
5
Cancer enriched
Detected in many
23
Cell type enhanced
Detected in some
null
Group enriched
Detected in some
9
3
0
3
[ "Breast Invasive Carcinoma", "Head and Neck Squamous Cell Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Head and Neck Squamous Cell Carcinoma", "Lung Adenocarcinoma" ]
6,445
8
ENSG00000132196
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7
[ "P56937" ]
1
162790702-162812823
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA047496" ]
[ "PRAP", "SDR37C1" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Lipid biosynthesis", "Lipid metabolism", "Steroid biosynthesis" ]
[ "Oxidoreductase" ]
[]
[]
[]
[]
[]
null
Approved
null
1
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 49: Hindbrain - Mixed function
Cluster 71: Lymphoma - Inflammatory response
Cluster 10: Epididymal principal cells - Sperm maturation microenvironment
Cluster 31: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
6,446
5
ENSG00000132199
ENOSF1
Enolase superfamily member 1
[ "Q7L5Y1" ]
18
670318-712662
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047829" ]
[ "FUCD", "HSRTSBETA", "rTS", "TYMSAS" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Isomerase", "Lyase" ]
[ "Dyskeratosis congenita" ]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 11: White matter - Signal transduction
Cluster 13: Non-specific - Mixed function
Cluster 7: Non-specific - Transcription
Cluster 72: Kidney - Transmembrane transport
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
5
2
4
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
6,447
4
ENSG00000132205
EMILIN2
Elastin microfibril interfacer 2
[ "Q9BXX0" ]
18
2847006-2916003
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA064576" ]
[ "FLJ33200", "FOAP-10" ]
[ "Plasma proteins", "Predicted secreted proteins" ]
[ "Cell adhesion" ]
[]
[]
[]
[]
[ "Secreted to extracellular matrix" ]
[ "Cell adhesion" ]
null
Supported
null
2
null
null
Cluster 41: Basophils - Unknown function
Cluster 30: White matter - Myelination
Cluster 64: Connective tissue cells - ECM organization
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 69: Parathyroid gland - Mixed function
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
0
0
0
[]
[]
[]
6,448
9
ENSG00000132207
SLX1A
SLX1 homolog A, structure-specific endonuclease subunit
[ "Q9BQ83" ]
16
30193875-30197561
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047038" ]
[ "GIYD1" ]
[ "Predicted intracellular proteins" ]
[ "DNA damage", "DNA recombination", "DNA repair" ]
[ "Endonuclease", "Hydrolase", "Nuclease" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Uncertain
null
7
null
null
Cluster 25: Non-specific - Unknown function
Cluster 6: Non-specific - Immune response
Cluster 54: Non-specific - Transcription
Cluster 22: Non-specific - Basic cellular functions
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
6,449
7
ENSG00000132254
ARFIP2
ADP ribosylation factor interacting protein 2
[ "P53365" ]
11
6474683-6481479
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB032985", "HPA038156", "HPA038157" ]
[ "POR1" ]
[ "Predicted intracellular proteins" ]
[ "Autophagy" ]
[]
[]
[ "Nucleoplasm", "Nucleoli", "Golgi apparatus" ]
[]
[]
[]
Approved
Approved
null
64
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 23: Choroid plexus - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 70: Intestinal goblet cells - Mucin production
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
6,450
4
ENSG00000132256
TRIM5
Tripartite motif containing 5
[ "Q9C035" ]
11
5663195-5938619
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB013497", "HPA023420", "HPA023422" ]
[ "RNF88", "TRIM5alpha" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Antiviral defense", "Autophagy", "Host-virus interaction", "Immunity", "Innate immunity", "Ubl conjugation pathway" ]
[ "Transferase" ]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Approved
null
17
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 8: Immune cells - Immune response
Cluster 31: Non-specific - Antiviral immune response
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
6
0
6
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Chromophobe", "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma", "Rectum Adenocarcinoma" ]
6,451
4
ENSG00000132259
CNGA4
Cyclic nucleotide gated channel subunit alpha 4
[ "Q8IV77" ]
11
6234765-6244479
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA074128" ]
[ "CNCA2", "CNG5", "CNGB2", "OCNC2", "OCNCb" ]
[ "Predicted membrane proteins", "Voltage-gated ion channels" ]
[ "Calcium transport", "Ion transport", "Olfaction", "Sensory transduction", "Transport" ]
[ "Calcium channel", "Ion channel", "Ligand-gated ion channel" ]
[]
[ "Nucleoplasm", "Plasma membrane" ]
[]
[]
[]
Uncertain
null
null
10
null
null
null
Cluster 46: Brainstem - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 65: Non-specific - Cell growth & division
Cluster 48: Ciliated tissues - Cilium organization
Group enriched
Detected in some
8
Not detected
Not detected
null
Cancer enriched
Detected in single
4
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
6,452
2
ENSG00000132274
TRIM22
Tripartite motif containing 22
[ "Q8IYM9" ]
11
5689610-5737089
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003307", "HPA003575" ]
[ "GPSTAF50", "RNF94", "STAF50" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Antiviral defense", "Host-virus interaction", "Transcription", "Transcription regulation", "Ubl conjugation pathway" ]
[ "Repressor", "Transferase" ]
[]
[ "Nucleoplasm", "Nuclear bodies" ]
[ "Golgi apparatus" ]
[]
[]
Supported
Approved
null
7
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 9: Non-specific - Receptor signaling
Cluster 55: Lymphoma - Immune response
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 66: Lymphoid tissue - Immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
6,453
6
ENSG00000132275
RRP8
Ribosomal RNA processing 8
[ "O43159" ]
11
6595072-6603616
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038487", "HPA057562" ]
[ "KIAA0409", "NML" ]
[ "Predicted intracellular proteins" ]
[ "rRNA processing", "Transcription", "Transcription regulation" ]
[ "Chromatin regulator", "Methyltransferase", "Repressor", "Transferase" ]
[]
[ "Nucleoplasm", "Nucleoli", "Cytosol" ]
[]
[]
[]
Supported
Approved
null
83
null
null
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 13: Oligodendrocytes - Mixed function
Cluster 35: RS4;11 - Unknown function
Cluster 17: Non-specific - RNA processing
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
6,454
3
ENSG00000132294
EFR3A
EFR3 homolog A
[ "Q14156" ]
8
131904093-132013642
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA022859", "HPA023092", "HPA023402" ]
[ "KIAA0143" ]
[ "Disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Autism", "Autism spectrum disorder" ]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Supported
Enhanced
null
5
null
null
Cluster 33: Non-specific - ATP binding
Cluster 24: Neurons - Mixed function
Cluster 40: Non-specific - Unknown function
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 42: Retina - Visual perception
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
6,456
7
ENSG00000132297
HHLA1
HERV-H LTR-associating 1
[ "C9JL84" ]
8
132061480-132111159
Evidence at transcript level
No human protein/transcript evidence
Evidence at transcript level
Evidence at transcript level
[]
[ "PLA2L" ]
[ "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted - unknown location" ]
[ "No annotated function" ]
null
null
null
null
null
null
null
null
Cluster 34: Testis cancer - Unknown function
Cluster 109: Neurons - Neuronal signaling
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
6,457
7
ENSG00000132300
PTCD3
Pentatricopeptide repeat domain 3
[ "Q96EY7" ]
2
86106223-86142157
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041154", "HPA041382" ]
[ "DKFZp666K071", "FLJ20758" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins", "Ribosomal proteins" ]
[ "Translation regulation" ]
[ "Ribonucleoprotein", "Ribosomal protein", "RNA-binding", "rRNA-binding" ]
[ "Primary mitochondrial disease" ]
[ "Mitochondria" ]
[]
[]
[]
Supported
Supported
null
93
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 50: Non-specific - Nucleic acid binding
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 17: Non-specific - RNA processing
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Glioblastoma Multiforme", "Rectum Adenocarcinoma" ]
[ "Thyroid Carcinoma" ]
[ "Glioblastoma Multiforme", "Rectum Adenocarcinoma", "Thyroid Carcinoma" ]
6,458
2
ENSG00000132305
IMMT
Inner membrane mitochondrial protein
[ "Q16891" ]
2
86143932-86195472
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB022439", "HPA036164", "HPA036165" ]
[ "HMP", "Mic60", "MICOS60", "MINOS2", "P87", "P89" ]
[ "Essential proteins", "Predicted intracellular proteins", "Transporters" ]
[ "Host-virus interaction" ]
[]
[]
[ "Mitochondria" ]
[]
[]
[]
Enhanced
Supported
null
86
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 23: Choroid plexus - Mixed function
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 97: Non-specific - Cellular respiration
Cluster 52: Non-specific - Cellular respiration
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
6,459
9
ENSG00000132321
IQCA1
IQ motif containing with AAA domain 1
[ "Q86XH1" ]
2
236324147-236507535
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA031547" ]
[ "DRC11", "FLJ22527", "IQCA" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Flagellar centriole" ]
[ "Vesicles", "Primary cilium", "Primary cilium tip" ]
[]
[]
Approved
null
null
null
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 15: Kidney cancer - Membrane components
Cluster 28: Astrocytes - Homeostasis & neuron support
Cluster 1: Choroid plexus - Transmembrane transport
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
6,461
9
ENSG00000132323
ILKAP
ILK associated serine/threonine phosphatase
[ "Q9H0C8" ]
2
238170402-238203708
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA004752" ]
[ "DKFZP434J2031", "FLJ10181", "PPM1O" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Protein phosphatase" ]
[]
[]
[]
[]
[]
null
Uncertain
null
8
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 55: Non-specific - Transcription
Cluster 35: RS4;11 - Unknown function
Cluster 7: Non-specific - Transcription
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
2
2
1
[]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
6,462
7
ENSG00000132326
PER2
Period circadian regulator 2
[ "O15055" ]
2
238244044-238290102
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA053136", "HPA060510" ]
[ "KIAA0347" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Biological rhythms", "Transcription", "Transcription regulation" ]
[]
[ "Disease variant" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Enhanced
null
27
null
null
Cluster 33: Non-specific - ATP binding
Cluster 2: Neurons - Nucleosome
Cluster 54: Non-specific - Transcription
Cluster 38: Secretory epithelial cells - Exocrine secretion
Cluster 21: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
6,463
6
ENSG00000132329
RAMP1
Receptor activity modifying protein 1
[ "O60894" ]
2
237858893-237912106
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA057814" ]
[]
[ "FDA approved drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Transport" ]
[ "Receptor" ]
[ "FDA approved drug targets" ]
[ "Nucleoplasm", "Nuclear membrane" ]
[]
[]
[]
Approved
null
null
7
null
null
Cluster 15: NK-cells - Unknown function
Cluster 39: Astrocytes - Mixed function
Cluster 60: Prostate cancer - Unknown function
Cluster 62: Smooth muscle cells - Muscle contraction
Cluster 74: Non-specific - Signal transduction
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in some
18
1
0
1
[]
[ "Stomach Adenocarcinoma" ]
[ "Stomach Adenocarcinoma" ]
6,464
1
ENSG00000132330
SCLY
Selenocysteine lyase
[ "Q96I15" ]
2
238060924-238099413
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA020190", "HPA055760" ]
[ "SCL" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Lyase", "Transferase" ]
[]
[ "Golgi apparatus" ]
[]
[]
[]
Enhanced
Uncertain
null
8
null
null
Cluster 25: Non-specific - Unknown function
Cluster 26: Oligodendrocytes - Mixed function
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 90: Elongating spermatids - Spermiogenesis: Elongation
Cluster 70: Non-specific - Protein processing
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in some
6
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
6,465
5
ENSG00000132334
PTPRE
Protein tyrosine phosphatase receptor type E
[ "P23469" ]
10
127907103-128085855
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA015870", "HPA021872" ]
[ "PTPE" ]
[ "Enzymes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Hydrolase", "Protein phosphatase" ]
[]
[ "Intermediate filaments" ]
[]
[]
[]
Approved
Supported
null
8
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 51: Neurons - Mixed function
Cluster 32: Non-specific - Cell proliferation
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma", "Uterine Corpus Endometrial Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma", "Uterine Corpus Endometrial Carcinoma" ]
6,466
9
ENSG00000132341
RAN
RAN, member RAS oncogene family
[ "P62826" ]
12
130872037-130877678
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA063353" ]
[ "ARA24", "Gsp1", "TC4" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins", "Transporters" ]
[ "Cell cycle", "Cell division", "Host-virus interaction", "Mitosis", "Protein transport", "Transport" ]
[ "Hydrolase" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
null
null
272
No
No
Cluster 12: Non-specific - Mitochondrial translation
Cluster 21: Non-specific - Metabolism
Cluster 38: Non-specific - Transcription
Cluster 17: Non-specific - RNA processing
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
5
2
5
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Bladder Urothelial Carcinoma", "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Bladder Urothelial Carcinoma", "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
6,467
4
ENSG00000132356
PRKAA1
Protein kinase AMP-activated catalytic subunit alpha 1
[ "Q13131" ]
5
40759389-40798374
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB005050", "HPA035409", "HPA064946" ]
[ "AMPKa1" ]
[ "Enzymes", "FDA approved drug targets", "Predicted intracellular proteins" ]
[ "Autophagy", "Biological rhythms", "Cholesterol biosynthesis", "Cholesterol metabolism", "Fatty acid biosynthesis", "Fatty acid metabolism", "Host-virus interaction", "Lipid biosynthesis", "Lipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabo...
[ "Chromatin regulator", "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[ "FDA approved drug targets" ]
[ "Nuclear speckles" ]
[ "Primary cilium", "Basal body", "Cytosol" ]
[]
[]
Supported
Supported
null
90
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 45: Non-specific - Mixed function
Cluster 29: Non-specific - Unknown function
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 57: Testis - Spermatogenesis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
6,468
1
ENSG00000132357
CARD6
Caspase recruitment domain family member 6
[ "Q9BX69" ]
5
40841308-40860175
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA041933" ]
[ "CINCIN1" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Apoptosis" ]
[]
[]
[]
[]
[]
[]
null
Approved
null
null
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 12: Non-specific - Vasculature
Cluster 48: Adipocytes & Endothelial cells - Angiogenesis
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 66: Lymphoid tissue - Immune response
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
6,469
1
ENSG00000132359
RAP1GAP2
RAP1 GTPase activating protein 2
[ "Q684P5" ]
17
2755705-3037741
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA022148", "HPA022896" ]
[ "GARNL4", "KIAA1039" ]
[ "Predicted intracellular proteins" ]
[]
[ "GTPase activation" ]
[]
[ "Nuclear membrane", "Cytosol" ]
[ "Perinuclear theca", "Flagellar centriole", "Principal piece" ]
[]
[]
Approved
Approved
null
1
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 53: Neurons - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 8: Pancreas - Proteolysis
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
0
0
0
[]
[]
[]
6,470
6
ENSG00000132361
CLUH
Clustered mitochondria homolog
[ "O75153" ]
17
2689386-2712663
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA031505", "HPA044346" ]
[ "CLU1", "KIAA0664" ]
[ "Predicted intracellular proteins" ]
[]
[ "RNA-binding" ]
[]
[ "Vesicles" ]
[ "Nucleoli fibrillar center" ]
[]
[]
Approved
Uncertain
null
28
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 32: Cerebral cortex - Mixed function
Cluster 42: Non-specific - Unknown function
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
6,471
3