ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000145428 | RNF175 | Ring finger protein 175 | [
"Q8N4F7"
] | 4 | 153710160-153760024 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA035837"
] | [
"FLJ34190"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 2 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 1: Neurons - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 10: Brain - Synaptic signal transduction | Tissue enriched | Detected in many | 5 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 3 | 0 | 3 | [
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 8,575 | 2 |
ENSG00000145431 | PDGFC | Platelet derived growth factor C | [
"Q9NRA1"
] | 4 | 156760454-156971799 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA009134"
] | [
"fallotein",
"SCDGF"
] | [
"Predicted secreted proteins",
"RAS pathway related proteins"
] | [] | [
"Developmental protein",
"Growth factor",
"Mitogen"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [
"Secreted to blood"
] | [
"Growth factor"
] | Supported | Approved | null | 3 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 5: Rhabdoid - Unknown function | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 69: Parathyroid gland - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 8,576 | 2 |
ENSG00000145439 | CBR4 | Carbonyl reductase 4 | [
"Q8N4T8"
] | 4 | 168863770-169010275 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037499"
] | [
"FLJ14431",
"SDR45C1"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Fatty acid biosynthesis",
"Fatty acid metabolism",
"Lipid biosynthesis",
"Lipid metabolism"
] | [
"Oxidoreductase"
] | [] | [] | [] | [] | [] | null | Supported | null | 21 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 26: Oligodendrocytes - Mixed function | Cluster 60: Prostate cancer - Unknown function | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 16: Liver & Kidney - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 17 | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 8,577 | 9 |
ENSG00000145451 | GLRA3 | Glycine receptor alpha 3 | [
"O75311"
] | 4 | 174636920-174829247 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA078885"
] | [] | [
"FDA approved drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Chloride channel",
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [
"FDA approved drug targets"
] | [
"Vesicles",
"Plasma membrane"
] | [] | [] | [] | Approved | null | null | 1 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 46: Lymphoma - Humoral immune response | Cluster 109: Neurons - Neuronal signaling | Cluster 73: Brain - Neuronal signaling | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in single | null | Cancer enriched | Detected in single | 4 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,578 | 3 |
ENSG00000145476 | CYP4V2 | Cytochrome P450 family 4 subfamily V member 2 | [
"Q6ZWL3"
] | 4 | 186191567-186213463 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA029122"
] | [
"CYP4AH1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins"
] | [
"Lipid metabolism",
"Sensory transduction",
"Vision"
] | [
"Monooxygenase",
"Oxidoreductase"
] | [
"Corneal dystrophy",
"Disease variant"
] | [
"Nuclear speckles"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 8: Immune cells - Immune response | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 20: Non-specific - Transcription regulation | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,579 | 8 |
ENSG00000145491 | ROPN1L | Rhophilin associated tail protein 1 like | [
"Q96C74"
] | 5 | 10441524-10472029 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039193",
"HPA041830"
] | [
"ASP",
"FLJ25776",
"RSPH11"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Primary cilium transition zone",
"Mid piece",
"Principal piece",
"End piece"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | Supported | Enhanced | null | 6 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 17: Choroid plexus - Cilium | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 79: Testis - Spermatogenesis | Tissue enriched | Detected in some | 12 | Low cancer specificity | Detected in some | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Group enriched | Detected in many | 12 | 1 | 0 | 1 | [
"Breast Invasive Carcinoma"
] | [] | [
"Breast Invasive Carcinoma"
] | 8,580 | 5 |
ENSG00000145494 | NDUFS6 | NADH:ubiquinone oxidoreductase subunit S6 | [
"O75380"
] | 5 | 1801407-1816048 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA064221"
] | [
"CI-13kA"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Electron transport",
"Respiratory chain",
"Transport"
] | [] | [
"Disease variant",
"Primary mitochondrial disease"
] | [] | [] | [] | [] | null | Supported | null | 89 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 21: Non-specific - Metabolism | Cluster 29: Non-specific - Unknown function | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 8,581 | 6 |
ENSG00000145495 | MARCHF6 | Membrane associated ring-CH-type finger 6 | [
"O60337"
] | 5 | 10353695-10440388 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040841",
"HPA063246"
] | [
"MARCH-VI",
"MARCH6",
"RNF176",
"TEB4"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Epilepsy"
] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Approved | null | 7 | null | null | Cluster 32: Basophils - Transcription | Cluster 31: Non-specific - Transcription | Cluster 29: Non-specific - Unknown function | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 8,582 | 1 |
ENSG00000145506 | NKD2 | NKD inhibitor of WNT signaling pathway 2 | [
"Q969F2"
] | 5 | 1008802-1038943 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049463"
] | [
"Naked2"
] | [
"Predicted intracellular proteins"
] | [
"Exocytosis",
"Transport",
"Wnt signaling pathway"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 14 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 32: Non-specific - Cell proliferation | Cluster 104: Brain endothelial cells - Blood brain barrier | Cluster 5: Spleen - Immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,583 | 6 |
ENSG00000145526 | CDH18 | Cadherin 18 | [
"Q13634"
] | 5 | 19471296-20575873 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA014416"
] | [
"CDH14",
"EY-CADHERIN"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Cell adhesion"
] | null | Uncertain | null | null | null | Yes | null | Cluster 2: Neurons - Nucleosome | Cluster 15: Kidney cancer - Membrane components | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Uterine Corpus Endometrial Carcinoma"
] | [
"Uterine Corpus Endometrial Carcinoma"
] | 8,584 | 3 |
ENSG00000145545 | SRD5A1 | Steroid 5 alpha-reductase 1 | [
"P18405"
] | 5 | 6633427-6674386 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051402"
] | [] | [
"Cancer-related genes",
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Differentiation",
"Lipid metabolism",
"Sexual differentiation"
] | [
"Oxidoreductase"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | Cluster 41: Basophils - Unknown function | Cluster 37: Neurons - Mixed function | Cluster 29: Non-specific - Unknown function | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 8,586 | 8 |
ENSG00000145555 | MYO10 | Myosin X | [
"Q9HD67"
] | 5 | 16661907-16936288 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB015224",
"HPA024223"
] | [
"KIAA0799",
"MyoX"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transport"
] | [
"Actin-binding",
"Calmodulin-binding",
"Motor protein",
"Myosin"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [
"Nucleoli rim"
] | [] | [] | Supported | Enhanced | null | 11 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 53: Neurons - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 36: Brain & Liver - Signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 4 | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Bladder Urothelial Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,587 | 6 |
ENSG00000145569 | OTULINL | OTU deubiquitinase with linear linkage specificity like | [
"Q9NUU6"
] | 5 | 14581792-14616180 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA046638"
] | [
"FAM105A",
"FLJ11127",
"NET20"
] | [
"Enzymes",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoli",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 15 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 8,588 | 6 |
ENSG00000145592 | RPL37 | Ribosomal protein L37 | [
"P61927"
] | 5 | 40825262-40835222 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"L37"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein",
"RNA-binding",
"rRNA-binding"
] | [] | [] | [] | [] | [] | null | null | null | 6 | null | null | Cluster 18: Non-specific - Translation | Cluster 7: Non-specific - Ribosome | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma"
] | 8,589 | 2 |
ENSG00000145604 | SKP2 | S-phase kinase associated protein 2 | [
"Q13309"
] | 5 | 36151989-36196849 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB013491",
"CAB013533",
"HPA051196",
"HPA054633"
] | [
"FBL1",
"FBXL1",
"p45"
] | [
"Cancer-related genes",
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Antiviral defense",
"Host-virus interaction",
"Immunity",
"Innate immunity",
"Ubl conjugation pathway"
] | [] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Cytosol"
] | [
"Nucleoli"
] | [] | [] | Supported | Approved | null | 130 | null | Yes | Cluster 46: Basophils - Proteolysis | Cluster 53: Neurons - Mixed function | Cluster 33: Sarcoma - Muscle contraction | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Lung Squamous Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | 8,590 | 2 |
ENSG00000145623 | OSMR | Oncostatin M receptor | [
"Q99650"
] | 5 | 38845858-38945596 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA017278"
] | [
"OSMRB",
"OSMRbeta"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [
"Amyloidosis",
"Disease variant"
] | [
"Nucleoli"
] | [] | [
"Intracellular and membrane"
] | [
"Receptor"
] | Approved | Approved | null | 35 | null | null | null | Cluster 44: Non-specific - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 103: Non-specific - Basic cellular processes | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 8,591 | 3 |
ENSG00000145626 | UGT3A1 | UDP glycosyltransferase family 3 member A1 | [
"Q6NUS8"
] | 5 | 35951006-36001028 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA047697",
"HPA056290"
] | [
"FLJ34658"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 1 | null | null | null | Cluster 9: Non-specific - Receptor signaling | Cluster 33: Sarcoma - Muscle contraction | Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase | Cluster 16: Liver & Kidney - Metabolism | Group enriched | Detected in some | 6 | Group enriched | Detected in some | 5 | Group enriched | Detected in some | 9 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,592 | 8 |
ENSG00000145632 | PLK2 | Polo like kinase 2 | [
"Q9NYY3"
] | 5 | 58453982-58460139 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009624",
"HPA069329"
] | [
"SNK"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Tumor suppressor"
] | [
"Nucleoplasm",
"Mitochondria",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 7 | null | null | Cluster 41: Basophils - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 20: Non-specific - Transcription regulation | Cluster 5: Spleen - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 4 | 0 | 0 | 0 | [] | [] | [] | 8,593 | 6 |
ENSG00000145642 | SHISAL2B | Shisa like 2B | [
"A6NKW6"
] | 5 | 64690442-64718190 | Evidence at protein level | Evidence at protein level | No human protein/transcript evidence | Evidence at transcript level | [
"HPA011778"
] | [
"FAM159B"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 5: Rhabdoid - Unknown function | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 8: Pancreas - Proteolysis | Group enriched | Detected in some | 9 | Cancer enriched | Detected in single | 19 | Cancer enriched | Detected in single | 12 | Cell type enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,594 | 5 |
ENSG00000145649 | GZMA | Granzyme A | [
"P12544"
] | 5 | 55102646-55110252 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054134",
"HPA076751"
] | [
"CTLA3",
"HFSP"
] | [
"Enzymes",
"Predicted secreted proteins"
] | [
"Cytolysis"
] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | Enhanced | null | 4 | null | null | Cluster 15: NK-cells - Unknown function | Cluster 8: Immune cells - Immune response | Cluster 59: Leukemia - T-cell receptor | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in some | 5 | Low cancer specificity | Detected in all | null | Group enriched | Detected in some | 42 | Group enriched | Detected in all | 15 | 2 | 0 | 2 | [
"Breast Invasive Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme"
] | 8,595 | 7 |
ENSG00000145675 | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1 | [
"P27986"
] | 5 | 68215740-68301821 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001216",
"CAB004268"
] | [
"GRB1",
"p85",
"p85-ALPHA"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Host-virus interaction",
"Protein transport",
"Stress response",
"Transport"
] | [
"GTPase activation"
] | [
"Cancer-related genes",
"Disease variant",
"Dwarfism"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 190 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 53: Neurons - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 8,596 | 6 |
ENSG00000145681 | HAPLN1 | Hyaluronan and proteoglycan link protein 1 | [
"P10915"
] | 5 | 83637805-83720855 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA019105",
"HPA019482",
"HPA025238"
] | [
"CRTL1"
] | [
"Predicted secreted proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | Approved | Enhanced | Approved | 1 | null | null | null | Cluster 24: Neurons - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enriched | Detected in some | 7 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,597 | 6 |
ENSG00000145685 | LHFPL2 | LHFPL tetraspan subfamily member 2 | [
"Q6ZUX7"
] | 5 | 78485215-78770021 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA042402",
"HPA076743"
] | [
"KIAA0206"
] | [
"Predicted membrane proteins"
] | [
"Fertilization"
] | [] | [] | [
"Plasma membrane"
] | [
"Nuclear bodies",
"Vesicles"
] | [] | [] | Approved | Uncertain | null | 9 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 20: Macrophages & Microglia - Immune response | Cluster 69: Skin cancer - ECM organization | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 8,598 | 5 |
ENSG00000145687 | SSBP2 | Single stranded DNA binding protein 2 | [
"P81877"
] | 5 | 81412804-81751797 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB020834",
"HPA068605",
"HPA071780"
] | [
"HSPC116"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Approved | null | 63 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 55: Non-specific - Transcription | Cluster 6: Leukemia - Signal transduction | Cluster 91: Pituicytes/FSC - Homeostasis & neuron support | Cluster 80: Thymus - Adaptive immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Breast Invasive Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Rectum Adenocarcinoma"
] | 8,599 | 6 |
ENSG00000145692 | BHMT | Betaine--homocysteine S-methyltransferase | [
"Q93088"
] | 5 | 79111809-79132288 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038285",
"HPA058310"
] | [
"BHMT1"
] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Methyltransferase",
"Transferase"
] | [
"FDA approved drug targets"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | null | No | null | null | Cluster 51: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 16: Liver & Kidney - Metabolism | Group enriched | Detected in some | 80 | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,600 | 6 |
ENSG00000145700 | ANKRD31 | Ankyrin repeat domain 31 | [
"Q8N7Z5"
] | 5 | 75068275-75236911 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA038028",
"HPA057566"
] | [
"FLJ40191"
] | [
"Predicted intracellular proteins"
] | [
"DNA recombination",
"Meiosis"
] | [] | [] | [
"Nucleoplasm",
"Centrosome"
] | [
"Nucleoli",
"Vesicles"
] | [] | [] | Approved | Enhanced | null | null | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in single | 7 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enriched | Detected in many | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,601 | 3 |
ENSG00000145703 | IQGAP2 | IQ motif containing GTPase activating protein 2 | [
"Q13576"
] | 5 | 76403285-76708132 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004241",
"HPA037403",
"HPA037404"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Calmodulin-binding"
] | [] | [
"Vesicles",
"Plasma membrane"
] | [] | [] | [] | Approved | Uncertain | null | 19 | null | null | Cluster 41: Basophils - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 49: HMC-1 - Innate immune response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 21: Testis - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 8,602 | 9 |
ENSG00000145708 | CRHBP | Corticotropin releasing hormone binding protein | [
"P24387"
] | 5 | 76953045-76981158 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036234",
"HPA046120"
] | [
"CRF-BP",
"CRFBP"
] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"No annotated function"
] | null | Approved | Supported | 2 | null | null | null | Cluster 14: Neurons - Synaptic function | Cluster 64: Connective tissue cells - ECM organization | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in some | 6 | Group enriched | Detected in some | 4 | Cell type enriched | Detected in some | 9 | Not detected in immune cells | Not detected | null | 2 | 4 | 0 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,603 | 1 |
ENSG00000145721 | LIX1 | Limb and CNS expressed 1 | [
"Q8N485"
] | 5 | 97091867-97142753 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA058426"
] | [
"C5orf11",
"Lft"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [
"Vesicles",
"Cytokinetic bridge"
] | [] | [] | Approved | Uncertain | null | 4 | Yes | null | Cluster 34: B-cells - Unknown function | Cluster 39: Astrocytes - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 46: Brain & retina - Neuronal signaling | Group enriched | Detected in some | 6 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in single | null | 0 | 0 | 0 | [] | [] | [] | 8,605 | 8 |
ENSG00000145723 | GIN1 | Gypsy retrotransposon integrase 1 | [
"Q9NXP7"
] | 5 | 103086000-103120138 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA037402",
"HPA061362"
] | [
"FLJ20125",
"GIN-1",
"TGIN1",
"ZH2C2"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | [] | Approved | Approved | null | 2 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 55: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 8,606 | 3 |
ENSG00000145725 | PPIP5K2 | Diphosphoinositol pentakisphosphate kinase 2 | [
"O43314"
] | 5 | 103120149-103212799 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037895",
"HPA038442"
] | [
"CFAP160",
"DFNB100",
"HISPPD1",
"KIAA0433",
"VIP2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Hearing"
] | [
"Kinase",
"Transferase"
] | [
"Deafness",
"Disease variant",
"Non-syndromic deafness"
] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 6 | null | null | Cluster 41: Basophils - Unknown function | Cluster 37: Neurons - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 15: Bone marrow - Innate immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Ovary Serous Cystadenocarcinoma",
"Thyroid Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Thyroid Carcinoma"
] | 8,607 | 6 |
ENSG00000145730 | PAM | Peptidylglycine alpha-amidating monooxygenase | [
"P19021"
] | 5 | 102753981-103029730 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB026119",
"HPA042260"
] | [
"PAL",
"PHM"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [
"Lipid metabolism"
] | [
"Lyase",
"Monooxygenase",
"Multifunctional enzyme",
"Oxidoreductase"
] | [] | [
"Golgi apparatus",
"Cytosol"
] | [] | [
"Secreted in other tissues"
] | [
"Enzyme"
] | Approved | Enhanced | null | 2 | null | null | Cluster 1: T-cells - Unknown function | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 15: Kidney cancer - Membrane components | Cluster 96: Enteroendocrine cells - Neuropeptide signaling | Cluster 35: Non-specific - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,608 | 3 |
ENSG00000145740 | SLC30A5 | Solute carrier family 30 member 5 | [
"Q8TAD4"
] | 5 | 69093991-69131069 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035373"
] | [
"FLJ12496",
"FLJ12756",
"MGC5499",
"ZnT-5",
"ZNT5",
"ZNTL1",
"ZTL1"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Antiport",
"Ion transport",
"Transport",
"Zinc transport"
] | [] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 20 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 50: Non-specific - Nucleic acid binding | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 8: Non-specific - Secretory pathway | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,611 | 1 |
ENSG00000145741 | BTF3 | Basic transcription factor 3 | [
"P20290"
] | 5 | 73498408-73505667 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB013007",
"HPA056420",
"HPA074056"
] | [
"BTF3a",
"BTF3b",
"NACB"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transcription",
"Transcription regulation",
"Transport"
] | [
"Chaperone"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 68 | null | Yes | Cluster 33: Non-specific - ATP binding | Cluster 7: Non-specific - Ribosome | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,612 | 1 |
ENSG00000145743 | FBXL17 | F-box and leucine rich repeat protein 17 | [
"Q9UF56"
] | 5 | 107859035-108382098 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036410",
"HPA036411"
] | [
"DKFZP434C1715",
"Fbl17",
"Fbx13",
"FBXO13"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Neurogenesis",
"Ubl conjugation pathway"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Uncertain | null | 38 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 60: Prostate cancer - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 8,613 | 3 |
ENSG00000145757 | SPATA9 | Spermatogenesis associated 9 | [
"Q9BWV2"
] | 5 | 95652181-95698711 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA010848",
"HPA076967"
] | [
"FLJ35906",
"NYD-SP16"
] | [
"Predicted membrane proteins"
] | [
"Differentiation",
"Spermatogenesis"
] | [
"Developmental protein"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Approved | null | null | null | null | null | Cluster 16: Non-specific - Transcription | Cluster 47: Leukemia - Hemostasis | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 6: Testis - Spermatogenesis | Tissue enriched | Detected in some | 22 | Not detected | Not detected | null | Not detected | Not detected | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,614 | 4 |
ENSG00000145777 | TSLP | Thymic stromal lymphopoietin | [
"Q969D9"
] | 5 | 111070062-111078026 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA056350"
] | [] | [
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Cytokine"
] | [
"FDA approved drug targets"
] | [
"Golgi apparatus",
"Vesicles"
] | [] | [
"Secreted to blood"
] | [
"Cytokine"
] | Uncertain | null | null | null | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 17: Non-specific - RNA processing | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 8,615 | 5 |
ENSG00000145779 | TNFAIP8 | TNF alpha induced protein 8 | [
"O95379"
] | 5 | 119268692-119399688 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054434",
"HPA057089"
] | [
"GG2-1",
"MDC-3.13",
"SCC-S2"
] | [
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Uncertain | null | 10 | No | Yes | Cluster 22: Eosinophils - Transcription | Cluster 12: Non-specific - Vasculature | Cluster 51: Myeloma - Immunoglobulins | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 51: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,616 | 4 |
ENSG00000145780 | FEM1C | Fem-1 homolog C | [
"Q96JP0"
] | 5 | 115520908-115544775 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA059919",
"HPA060977"
] | [
"EUROIMAGE686608",
"EUROIMAGE783647",
"FEM1A",
"KIAA1785"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Approved | null | 8 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 16: Non-specific - Transcription | Cluster 71: Lymphoma - Inflammatory response | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 8,617 | 5 |
ENSG00000145781 | COMMD10 | COMM domain containing 10 | [
"Q9Y6G5"
] | 5 | 116085016-116412762 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045441",
"HPA054156"
] | [
"PTD002"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Ubl conjugation pathway"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 54 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 21: Non-specific - Metabolism | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 8,618 | 2 |
ENSG00000145782 | ATG12 | Autophagy related 12 | [
"O94817"
] | 5 | 115828200-115841837 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB013272",
"HPA068989"
] | [
"APG12",
"APG12L"
] | [
"Predicted intracellular proteins",
"Transporters"
] | [
"Autophagy",
"Host-virus interaction",
"Ubl conjugation pathway"
] | [] | [] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | [] | Approved | Uncertain | null | 42 | null | null | Cluster 24: Non-specific - Transcription | Cluster 28: Oligodendrocytes - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 7: Non-specific - Transcription | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma",
"Thyroid Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma",
"Thyroid Carcinoma"
] | 8,619 | 6 |
ENSG00000145794 | MEGF10 | Multiple EGF like domains 10 | [
"Q96KG7"
] | 5 | 127290796-127465737 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011401"
] | [
"KIAA1780",
"SR-F3"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion",
"Myogenesis",
"Phagocytosis"
] | [] | [
"Disease variant"
] | [
"Plasma membrane"
] | [] | [
"Intracellular and membrane"
] | [
"Cell adhesion"
] | Supported | null | null | 1 | null | null | null | Cluster 13: Oligodendrocytes - Mixed function | Cluster 33: Sarcoma - Muscle contraction | Cluster 80: Oligodendrocytes - Myelination | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in some | null | Group enriched | Detected in some | 4 | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 8,620 | 1 |
ENSG00000145808 | ADAMTS19 | ADAM metallopeptidase with thrombospondin type 1 motif 19 | [] | 5 | 129460281-129738683 | Evidence at transcript level | Evidence at transcript level | null | null | [
"HPA056171",
"HPA058438"
] | [] | [
"Predicted secreted proteins"
] | [] | [] | [] | [
"Vesicles",
"Midbody"
] | [] | [
"Secreted to extracellular matrix"
] | [] | Approved | Uncertain | null | null | Yes | null | null | Cluster 33: Neurons - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 57: Podocytes - Glomerular filtration | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in some | 5 | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,621 | 2 |
ENSG00000145819 | ARHGAP26 | Rho GTPase activating protein 26 | [
"Q9UNA1"
] | 5 | 142770377-143229011 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035106",
"HPA035107"
] | [
"GRAF",
"KIAA0621",
"OPHN1L",
"OPHN1L1"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"GTPase activation"
] | [
"Cancer-related genes",
"Disease variant",
"Proto-oncogene"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 11 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 34: Non-specific - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 4 | Group enriched | Detected in many | 4 | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 8,623 | 6 |
ENSG00000145824 | CXCL14 | C-X-C motif chemokine ligand 14 | [
"O95715"
] | 5 | 135570679-135579279 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB029996"
] | [
"BMAC",
"bolekine",
"BRAK",
"Kec",
"KS1",
"MIP-2g",
"NJAC",
"SCYB14"
] | [
"Predicted secreted proteins"
] | [
"Chemotaxis"
] | [
"Cytokine"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Chemokine"
] | null | Uncertain | null | 6 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 108: Fibroblasts - ECM organization | Cluster 9: Skin - Hair follicle development | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 8,624 | 2 |
ENSG00000145826 | LECT2 | Leukocyte cell derived chemotaxin 2 | [
"O14960"
] | 5 | 135922279-135954983 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043883",
"HPA058246"
] | [
"chm-II",
"chm2"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Chemotaxis"
] | [] | [] | [
"Cytosol"
] | [
"Vesicles"
] | [
"Secreted to blood"
] | [
"Other"
] | Supported | Enhanced | null | null | null | null | null | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 56: Non-specific - Sensory perception | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 53 | Low cancer specificity | Detected in some | null | Cancer enriched | Detected in some | 55 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 8,625 | 1 |
ENSG00000145832 | SLC25A48 | Solute carrier family 25 member 48 | [
"Q6ZT89"
] | 5 | 135476913-135889770 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA014674"
] | [
"FLJ44862"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [] | [] | [
"Intermediate filaments"
] | [
"Actin filaments"
] | [] | [] | Approved | Uncertain | null | 4 | null | null | null | Cluster 13: Oligodendrocytes - Mixed function | Cluster 65: Non-specific - Unknown function | Cluster 91: Pituicytes/FSC - Homeostasis & neuron support | Cluster 36: Brain & Liver - Signaling | Group enriched | Detected in some | 4 | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 8,626 | 8 |
ENSG00000145833 | DDX46 | DEAD-box helicase 46 | [
"Q7L014"
] | 5 | 134758771-134855133 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036554",
"HPA057501"
] | [
"FLJ25329",
"KIAA0801",
"Prp5",
"PRPF5"
] | [
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"Helicase",
"Hydrolase",
"RNA-binding"
] | [] | [
"Nuclear speckles"
] | [
"Nucleoli fibrillar center"
] | [] | [] | Supported | Supported | null | 25 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 8,627 | 7 |
ENSG00000145839 | IL9 | Interleukin 9 | [
"P15248"
] | 5 | 135892246-135895841 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [] | [
"HP40",
"IL-9",
"P40"
] | [
"Cancer-related genes",
"Predicted secreted proteins"
] | [] | [
"Cytokine",
"Growth factor"
] | [
"Cancer-related genes"
] | [] | [] | [
"Secreted to blood"
] | [
"Interleukin"
] | null | null | null | null | null | null | null | Cluster 13: Oligodendrocytes - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 47: Platelets - Hemostasis | null | Not detected | Not detected | null | Cancer enriched | Detected in single | 4 | Not detected | Not detected | null | Cell type enriched | Detected in single | 7 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,628 | 6 |
ENSG00000145850 | TIMD4 | T cell immunoglobulin and mucin domain containing 4 | [
"Q96H15"
] | 5 | 156919292-156963226 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA015625",
"CAB026027"
] | [
"TIM4"
] | [
"Plasma proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | Approved | Approved | null | 2 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 55: Lymphoma - Immune response | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 39: Testis - Nuclear processes | Group enriched | Detected in many | 6 | Group enriched | Detected in some | 4 | Cancer enriched | Detected in many | 5 | Cell type enhanced | Detected in some | null | Group enriched | Detected in some | 5 | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 8,629 | 4 |
ENSG00000145860 | RNF145 | Ring finger protein 145 | [
"Q96MT1"
] | 5 | 159157409-159210053 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA036562"
] | [
"FLJ31951"
] | [
"Enzymes",
"Predicted membrane proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nucleoplasm",
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 1 | null | null | Cluster 19: Eosinophils - Unknown function | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,630 | 1 |
ENSG00000145861 | C1QTNF2 | C1q and TNF related 2 | [
"Q9BXJ5"
] | 5 | 160347754-160370641 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA061290"
] | [
"CTRP2"
] | [
"Predicted secreted proteins"
] | [] | [] | [] | [
"Golgi apparatus",
"Centrosome"
] | [] | [
"Secreted to blood"
] | [
"Complement pathway"
] | Approved | Uncertain | null | 28 | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 33: Sarcoma - Muscle contraction | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 5 | 1 | 0 | 1 | [] | [
"Stomach Adenocarcinoma"
] | [
"Stomach Adenocarcinoma"
] | 8,631 | 4 |
ENSG00000145863 | GABRA6 | Gamma-aminobutyric acid type A receptor subunit alpha6 | [
"Q16445"
] | 5 | 161547063-161702593 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"CAB022462"
] | [] | [
"FDA approved drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Ion transport",
"Transport"
] | [
"Chloride channel",
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Approved | null | null | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 1: Neuronal - Visual perception | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 71: Cerebellum - Nervous system development | Tissue enriched | Detected in single | 264 | Not detected | Not detected | null | Not detected | Not detected | null | Group enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,632 | 9 |
ENSG00000145864 | GABRB2 | Gamma-aminobutyric acid type A receptor subunit beta2 | [
"P47870"
] | 5 | 161288429-161549044 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB001964",
"HPA067632"
] | [] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Chloride channel",
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [
"Disease variant",
"Epilepsy",
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Enhanced | null | 3 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in some | 7 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in some | 18 | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,633 | 6 |
ENSG00000145868 | FBXO38 | F-box protein 38 | [
"Q6PIJ6"
] | 5 | 148383935-148442836 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034821"
] | [
"Fbx38",
"FLJ13962",
"MOKA",
"SP329"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Adaptive immunity",
"Immunity",
"Ubl conjugation pathway"
] | [] | [
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Nucleoplasm",
"Plasma membrane"
] | [
"Primary cilium",
"Basal body"
] | [] | [] | Approved | Approved | null | 15 | null | No | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 28: Oligodendrocytes - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,634 | 7 |
ENSG00000145879 | SPINK7 | Serine peptidase inhibitor Kazal type 7 | [
"P58062"
] | 5 | 148312419-148315922 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036294"
] | [
"ECG2",
"ECRG2"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Protease inhibitor",
"Serine protease inhibitor"
] | [] | [] | [] | [
"Secreted in other tissues"
] | [
"Enzyme inhibitor"
] | null | Enhanced | null | 18 | null | null | null | null | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 84: Apical squamous epithelium - Cornification | Cluster 81: Squamous epithelium - Keratinization | Group enriched | Detected in some | 5 | Group enriched | Detected in some | 6 | Group enriched | Detected in many | 6 | Cell type enriched | Detected in some | 147 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,635 | 1 |
ENSG00000145882 | PCYOX1L | Prenylcysteine oxidase 1 like | [
"Q8NBM8"
] | 5 | 149358037-149369653 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037463",
"HPA038402"
] | [
"MGC3265"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Oxidoreductase"
] | [] | [
"Nucleoplasm",
"Mitochondria"
] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | Approved | Approved | null | 8 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 1: Neurons - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 109: Neurons - Neuronal signaling | Cluster 65: Brain - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 8,636 | 6 |
ENSG00000145888 | GLRA1 | Glycine receptor alpha 1 | [
"P23415"
] | 5 | 151822513-151924851 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA078885",
"CAB079042"
] | [
"STHE"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Chloride channel",
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [
"Disease variant",
"FDA approved drug targets"
] | [
"Vesicles",
"Plasma membrane"
] | [] | [] | [] | Approved | null | Supported | 2 | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 46: Brain & retina - Neuronal signaling | Tissue enriched | Detected in single | 7 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,637 | 9 |
ENSG00000145901 | TNIP1 | TNFAIP3 interacting protein 1 | [
"Q15025"
] | 5 | 151029945-151093577 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037893",
"HPA037894",
"HPA071950"
] | [
"ABIN-1",
"KIAA0113",
"NAF1",
"VAN"
] | [
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Inflammatory response"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 167 | null | null | Cluster 19: Eosinophils - Unknown function | Cluster 47: Endothelial cells - Vasculature | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,638 | 2 |
ENSG00000145907 | G3BP1 | G3BP stress granule assembly factor 1 | [
"Q13283"
] | 5 | 151771045-151812911 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004052",
"CAB037068",
"HPA072698"
] | [
"G3BP",
"HDH-VIII"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Host-virus interaction",
"Immunity",
"Innate immunity",
"Transport"
] | [
"DNA-binding",
"Endonuclease",
"Helicase",
"Hydrolase",
"Nuclease",
"RNA-binding"
] | [] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Supported | null | 266 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 55: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 8,639 | 8 |
ENSG00000145908 | ZNF300 | Zinc finger protein 300 | [
"Q96RE9"
] | 5 | 150894392-150904983 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028975",
"HPA051777"
] | [] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Nucleoli rim",
"Nuclear bodies"
] | [] | [] | Enhanced | Uncertain | null | 1 | null | null | null | Cluster 26: Oligodendrocytes - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 7: Non-specific - Transcription | Cluster 65: Brain - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cell type specificity | Detected in many | null | Immune cell enhanced | Detected in single | null | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 8,640 | 2 |
ENSG00000145911 | N4BP3 | NEDD4 binding protein 3 | [
"O15049"
] | 5 | 178113532-178126081 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030972",
"HPA030973",
"HPA061387"
] | [
"LZTS4"
] | [
"Predicted intracellular proteins"
] | [
"Immunity",
"Innate immunity",
"Neurogenesis"
] | [
"Developmental protein"
] | [] | [
"Nucleoplasm"
] | [
"Centrosome"
] | [] | [] | Supported | Approved | null | 31 | null | null | Cluster 34: B-cells - Unknown function | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 46: Lymphoma - Humoral immune response | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in many | 5 | Group enriched | Detected in some | 4 | 0 | 0 | 0 | [] | [] | [] | 8,641 | 6 |
ENSG00000145912 | NHP2 | NHP2 ribonucleoprotein | [
"Q9NX24"
] | 5 | 178149463-178153894 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044171",
"HPA050400"
] | [
"FLJ20479",
"NOLA2"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [
"Ribosome biogenesis",
"rRNA processing"
] | [
"Ribonucleoprotein",
"RNA-binding"
] | [
"Disease variant",
"Dyskeratosis congenita"
] | [] | [] | [] | [] | null | Enhanced | null | 21 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 27: Non-specific - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,642 | 1 |
ENSG00000145919 | BOD1 | Biorientation of chromosomes in cell division 1 | [
"Q96IK1"
] | 5 | 173607145-173616659 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA036293"
] | [
"FAM44B"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 5 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 15: Non-specific - Protein processing | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 8,644 | 3 |
ENSG00000145920 | CPLX2 | Complexin 2 | [
"Q6PUV4"
] | 5 | 175796310-175884021 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA071191",
"HPA074390"
] | [
"CPX-2",
"DKFZp547D155"
] | [
"Predicted intracellular proteins"
] | [
"Differentiation",
"Exocytosis",
"Mast cell degranulation",
"Neurogenesis",
"Neurotransmitter transport",
"Transport"
] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Uncertain | Supported | null | 5 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 27: Cerebellum - Synaptic function | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,645 | 7 |
ENSG00000145936 | KCNMB1 | Potassium calcium-activated channel subfamily M regulatory beta subunit 1 | [
"Q16558"
] | 5 | 170374671-170389634 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"hslo-beta"
] | [
"FDA approved drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Ion channel"
] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | null | null | null | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 49: Hindbrain - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 8,647 | 7 |
ENSG00000145945 | FAM50B | Family with sequence similarity 50 member B | [
"Q9Y247"
] | 6 | 3849373-3851320 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA064111",
"HPA067817"
] | [
"D6S2654E",
"X5L"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytokinetic bridge",
"Midbody"
] | [] | [] | Approved | Approved | null | 43 | Yes | null | Cluster 33: Non-specific - ATP binding | Cluster 33: Neurons - Mixed function | Cluster 71: Lymphoma - Inflammatory response | Cluster 64: Renal epithelial cells - Ion transport & homeostasis | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 8,648 | 8 |
ENSG00000145975 | FAM217A | Family with sequence similarity 217 member A | [
"Q8IXS0"
] | 6 | 4049434-4087344 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA035455"
] | [
"C6orf146",
"MGC43581"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 1 | null | null | null | null | Cluster 11: Neuronal - Sensory perception | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in some | 9 | Not detected | Not detected | null | Not detected | Not detected | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,650 | 2 |
ENSG00000145982 | FARS2 | Phenylalanyl-tRNA synthetase 2, mitochondrial | [
"O95363"
] | 6 | 5261044-5829192 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA018148",
"HPA028836"
] | [
"dJ236A3.1",
"FARS1",
"mtPheRS"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Aminoacyl-tRNA synthetase",
"Ligase"
] | [
"Disease variant",
"Hereditary spastic paraplegia",
"Neurodegeneration",
"Primary mitochondrial disease"
] | [] | [] | [] | [] | null | Approved | null | 63 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 23: Choroid plexus - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 7: Non-specific - Transcription | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 8,652 | 2 |
ENSG00000145990 | GFOD1 | Glucose-fructose oxidoreductase domain containing 1 | [
"Q9NXC2"
] | 6 | 13357830-13487662 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA029096"
] | [
"ADG-90",
"C6orf114",
"FLJ20330"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Plasma membrane"
] | [
"Secreted - unknown location"
] | [
"No annotated function"
] | Approved | Uncertain | null | 22 | No | No | Cluster 45: Eosinophils - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 49: HMC-1 - Innate immune response | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 41: Striated muscle - Muscle contraction | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 5 | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,653 | 7 |
ENSG00000146005 | PSD2 | Pleckstrin and Sec7 domain containing 2 | [
"Q9BQI7"
] | 5 | 139795808-139844466 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA054625"
] | [
"DKFZp761B0514",
"EFA6C"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [] | [] | [] | Approved | null | null | null | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 28: Astrocytes - Homeostasis & neuron support | Cluster 78: Brain - Neuronal signaling | Tissue enriched | Detected in some | 10 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in single | 45 | Group enriched | Detected in some | 9 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,655 | 6 |
ENSG00000146007 | ZMAT2 | Zinc finger matrin-type 2 | [
"Q96NC0"
] | 5 | 140698680-140706686 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA036518"
] | [
"FLJ31121",
"hSNU23",
"Snu23"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Mitochondria"
] | [] | [] | [] | Approved | Approved | null | 64 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,657 | 7 |
ENSG00000146013 | GFRA3 | GDNF family receptor alpha 3 | [
"O60609"
] | 5 | 138252380-138274621 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020731"
] | [
"GFRa-3"
] | [
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [] | [
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 1 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 96: Enteroendocrine cells - Neuropeptide signaling | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in some | 9 | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Lung Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma"
] | 8,658 | 6 |
ENSG00000146021 | KLHL3 | Kelch like family member 3 | [
"Q9UH77"
] | 5 | 137617500-137736089 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051291"
] | [
"KIAA1129"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Ubl conjugation pathway"
] | [
"Actin-binding"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Approved | null | 29 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 15: Non-specific - Transcription | Cluster 59: Leukemia - T-cell receptor | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 71: Cerebellum - Nervous system development | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enriched | Detected in many | 7 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,659 | 5 |
ENSG00000146038 | DCDC2 | Doublecortin domain containing 2 | [
"Q9UHG0"
] | 6 | 24171755-24358059 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031582",
"HPA031583",
"HPA031584"
] | [
"DCDC2A",
"DFNB66",
"KIAA1154",
"NPHP19",
"RU2"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation",
"Neurogenesis"
] | [] | [
"Ciliopathy",
"Deafness",
"Disease variant",
"Nephronophthisis",
"Non-syndromic deafness"
] | [
"Microtubules",
"Cytosol"
] | [
"Mitotic spindle",
"Centriolar satellite",
"Acrosome",
"Equatorial segment",
"Principal piece"
] | [] | [] | Approved | Enhanced | null | 26 | Yes | null | null | Cluster 17: Choroid plexus - Cilium | Cluster 15: Kidney cancer - Membrane components | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,660 | 5 |
ENSG00000146039 | SLC17A4 | Solute carrier family 17 member 4 | [
"Q9Y2C5"
] | 6 | 25754699-25781199 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [
"HPA055564"
] | [
"KIAA2138"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Sodium transport",
"Symport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 60: Prostate cancer - Unknown function | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 26: Kidney & Intestine - Metabolism | Group enriched | Detected in some | 8 | Cancer enhanced | Detected in single | null | Group enriched | Detected in many | 7 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,661 | 9 |
ENSG00000146047 | H2BC1 | H2B clustered histone 1 | [
"Q96A08"
] | 6 | 25726777-25727345 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011603",
"HPA042205",
"HPA043013"
] | [
"bA317E16.3",
"H2BFU",
"HIST1H2BA",
"STBP",
"TSH2B"
] | [
"Predicted intracellular proteins"
] | [] | [
"DNA-binding"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 65 | null | null | null | null | Cluster 4: Non-specific - Transcription | null | Cluster 6: Testis - Spermatogenesis | Tissue enriched | Detected in single | 50 | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,662 | 2 |
ENSG00000146063 | TRIM41 | Tripartite motif containing 41 | [
"Q8WV44"
] | 5 | 181222499-181235808 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024204"
] | [
"MGC1127",
"RINCK"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nucleoli fibrillar center"
] | [
"Nucleoplasm",
"Vesicles",
"Cytosol"
] | [] | [] | Supported | Approved | null | 135 | null | null | Cluster 39: T-cells - T-cell receptor | Cluster 47: Endothelial cells - Vasculature | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 3: Oligodendrocytes - Myelination | Group enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 8,664 | 7 |
ENSG00000146066 | HIGD2A | HIG1 hypoxia inducible domain family member 2A | [
"Q9BW72"
] | 5 | 176388751-176389761 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042715"
] | [
"MGC2198",
"RCF1B"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Electron transport",
"Respiratory chain",
"Transport"
] | [] | [] | [
"Mitochondria"
] | [
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 1 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 39: Astrocytes - Mixed function | Cluster 25: Non-specific - Ribosome | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 8,665 | 9 |
ENSG00000146067 | FAM193B | Family with sequence similarity 193 member B | [
"Q96PV7"
] | 5 | 177519789-177554586 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035847",
"HPA035848"
] | [
"FLJ10404",
"IRIZIO",
"KIAA1931"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | [] | Enhanced | Approved | null | 6 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 56: Non-specific - Sensory perception | Cluster 7: Non-specific - Transcription | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 8,666 | 7 |
ENSG00000146070 | PLA2G7 | Phospholipase A2 group VII | [
"Q13093"
] | 6 | 46704201-46735693 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"LDL-PLA2",
"PAFAH"
] | [
"Candidate cardiovascular disease genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted secreted proteins"
] | [
"Lipid degradation",
"Lipid metabolism",
"Phospholipid degradation",
"Phospholipid metabolism"
] | [
"Hydrolase"
] | [
"Asthma",
"Disease variant"
] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | null | null | 1 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 30: White matter - Myelination | Cluster 60: Prostate cancer - Unknown function | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in some | 8 | Cancer enhanced | Detected in all | null | Cell type enriched | Detected in some | 4 | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,667 | 1 |
ENSG00000146072 | TNFRSF21 | TNF receptor superfamily member 21 | [
"O75509"
] | 6 | 47231532-47309905 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006746",
"CAB009805"
] | [
"CD358",
"DR6"
] | [
"CD markers",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Adaptive immunity",
"Apoptosis",
"Host-virus interaction",
"Immunity"
] | [
"Receptor"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 4 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 30: White matter - Myelination | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 35 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 8,668 | 3 |
ENSG00000146083 | RNF44 | Ring finger protein 44 | [
"Q7L0R7"
] | 5 | 176526712-176538025 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038981"
] | [
"KIAA1100"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 9 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 6 | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 8,669 | 2 |
ENSG00000146085 | MMUT | Methylmalonyl-CoA mutase | [
"P22033"
] | 6 | 49430360-49463253 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035971",
"HPA035972"
] | [
"MCM",
"MUT"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Isomerase"
] | [
"Disease variant",
"FDA approved drug targets"
] | [
"Cytosol"
] | [
"Mitochondria"
] | [] | [] | Approved | Enhanced | null | 10 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 50: Non-specific - Nucleic acid binding | Cluster 28: Non-specific - Nuclear processes | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 8,670 | 2 |
ENSG00000146090 | RASGEF1C | RasGEF domain family member 1C | [
"Q8N431"
] | 5 | 180100795-180209211 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [
"HPA028242"
] | [
"FLJ35841"
] | [
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | null | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 1: Neuronal - Visual perception | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in some | 6 | Low cancer specificity | Detected in single | null | Cancer enhanced | Detected in some | null | Cell type enriched | Detected in many | 7 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,671 | 3 |
ENSG00000146094 | DOK3 | Docking protein 3 | [
"Q7L591"
] | 5 | 177501904-177511274 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA077312"
] | [
"FLJ22570"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [
"Nucleoplasm",
"Cytokinetic bridge",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 8 | Yes | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 49: Hindbrain - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 66: Lymphoid tissue - Immune response | Group enriched | Detected in many | 4 | Group enriched | Detected in all | 6 | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,672 | 4 |
ENSG00000146109 | ABT1 | Activator of basal transcription 1 | [
"Q9ULW3"
] | 6 | 26596953-26600739 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA077039"
] | [
"Esf2"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"RNA-binding"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | null | null | 197 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 15: Non-specific - Transcription | Cluster 28: Non-specific - Nuclear processes | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,673 | 9 |
ENSG00000146112 | PPP1R18 | Protein phosphatase 1 regulatory subunit 18 | [
"Q6NYC8"
] | 6 | 30676389-30687895 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044745",
"HPA051000"
] | [
"KIAA1949",
"phostensin"
] | [
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Enhanced | null | 83 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 6: Leukemia - Signal transduction | Cluster 102: Non-specific - Mixed function | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in some | 4 | Group enriched | Detected in all | 4 | 2 | 0 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 8,674 | 6 |
ENSG00000146122 | DAAM2 | Dishevelled associated activator of morphogenesis 2 | [
"Q86T65"
] | 6 | 39792298-39904877 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051300",
"HPA054630"
] | [
"KIAA0381",
"NPHS24"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Wnt signaling pathway"
] | [] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Supported | Approved | null | null | null | null | null | Cluster 13: Oligodendrocytes - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Cancer enriched | Detected in many | 6 | Group enriched | Detected in all | 4 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 8,675 | 4 |
ENSG00000146143 | PRIM2 | DNA primase subunit 2 | [
"P49643"
] | 6 | 57314805-57646850 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046566"
] | [
"PRIM2A"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA replication"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 20 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 16: Non-specific - Transcription | Cluster 28: Non-specific - Nuclear processes | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 61: Non-specific - Transcription | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 5 | 2 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 8,676 | 7 |
ENSG00000146151 | HMGCLL1 | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1 | [
"Q8TB92"
] | 6 | 55434373-55579197 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"bA418P12.1",
"DKFZP434G1411"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Lyase"
] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,678 | 9 |
ENSG00000146166 | LGSN | Lengsin, lens protein with glutamine synthetase domain | [
"Q5TDP6"
] | 6 | 63275951-63319983 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030957",
"HPA039983"
] | [
"GLULD1",
"LGS"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | [] | Approved | Enhanced | null | null | null | null | null | Cluster 6: Non-specific - Immune response | Cluster 7: Liver cancer - Metabolism | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 16: Liver & Kidney - Metabolism | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in some | 7 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,679 | 4 |
ENSG00000146192 | FGD2 | FYVE, RhoGEF and PH domain containing 2 | [
"Q7Z6J4"
] | 6 | 37005646-37029069 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA029145",
"HPA049692"
] | [
"ZFYVE4"
] | [
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [] | [] | [] | [] | [] | null | Approved | null | 5 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 20: Macrophages & Microglia - Immune response | Cluster 55: Lymphoma - Immune response | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 7 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 16 | 0 | 0 | 0 | [] | [] | [] | 8,680 | 5 |
ENSG00000146197 | SCUBE3 | Signal peptide, CUB domain and EGF like domain containing 3 | [
"Q8IX30"
] | 6 | 35213956-35253079 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040606"
] | [
"CEGF3",
"FLJ34743"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted secreted proteins"
] | [] | [] | [
"Disease variant",
"Dwarfism"
] | [
"Plasma membrane"
] | [] | [
"Secreted to blood"
] | [
"No annotated function"
] | Supported | Uncertain | null | 1 | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 83: Epicardial mesothelial cells - Basic cellular functions | Cluster 12: Smooth muscle tissue - ECM organization | Group enriched | Detected in many | 7 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in many | 6 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Thyroid Carcinoma"
] | [
"Thyroid Carcinoma"
] | 8,681 | 1 |
ENSG00000146205 | ANO7 | Anoctamin 7 | [
"Q6IWH7"
] | 2 | 241188509-241225976 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA078464"
] | [
"IPCA-5",
"NGEP",
"PCANAP5",
"PCANAP5L",
"TMEM16G"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Lipid transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | null | Cluster 11: White matter - Signal transduction | Cluster 24: Non-specific - Unknown function | Cluster 70: Intestinal goblet cells - Mucin production | Cluster 17: Intestine - Digestion | Group enriched | Detected in some | 7 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in many | 22 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Colon Adenocarcinoma"
] | [] | [
"Colon Adenocarcinoma"
] | 8,682 | 7 |
ENSG00000146215 | CRIP3 | Cysteine rich protein 3 | [
"Q6Q6R5"
] | 6 | 43299710-43308826 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036198"
] | [
"bA480N24.2",
"TLP",
"TLP-A"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 46: Lymphoma - Humoral immune response | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 35: Non-specific - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in many | 16 | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 8,683 | 7 |
ENSG00000146216 | TTBK1 | Tau tubulin kinase 1 | [
"Q5TCY1"
] | 6 | 43243481-43288258 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031735",
"HPA031736"
] | [
"KIAA1855"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Enhanced | null | 2 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 10: Brain - Synaptic signal transduction | Group enriched | Detected in some | 4 | Cancer enriched | Detected in single | 10 | Cancer enriched | Detected in some | 5 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,684 | 4 |
ENSG00000146221 | TCTE1 | T-complex-associated-testis-expressed 1 | [
"Q5JU00"
] | 6 | 44278734-44297698 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA031739"
] | [
"D6S46",
"DRC5",
"FAP155",
"MGC33600"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles",
"Mid piece"
] | [
"Cytosol"
] | [] | [] | Approved | null | null | null | null | null | null | Cluster 2: Neurons - Nucleosome | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 56: Ciliated tissues - Cilium organization | Group enriched | Detected in some | 9 | Cancer enriched | Detected in single | 5 | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,685 | 9 |
ENSG00000146223 | RPL7L1 | Ribosomal protein L7 like 1 | [
"Q6DKI1"
] | 6 | 42879616-42889925 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA046049",
"HPA050478"
] | [
"dJ475N16.4"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [
"Nucleoli",
"Mitochondria"
] | [] | [] | [] | Approved | null | null | 79 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 34: Non-specific - Mixed function | Cluster 28: Non-specific - Nuclear processes | Cluster 17: Non-specific - RNA processing | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma"
] | 8,686 | 2 |
ENSG00000146232 | NFKBIE | NFKB inhibitor epsilon | [
"O00221"
] | 6 | 44258166-44265788 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002692",
"HPA005941",
"CAB010272"
] | [
"IKBE"
] | [
"Cancer-related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [] | [
"Cancer-related genes"
] | [
"Nucleoli fibrillar center"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Supported | Supported | null | 20 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 25: Non-specific - Transcription | Cluster 55: Lymphoma - Immune response | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Breast Invasive Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 8,687 | 6 |
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