ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000162946
DISC1
DISC1 scaffold protein
[ "Q9NRI5" ]
1
231626790-232041272
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA048911" ]
[]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Neurogenesis", "Wnt signaling pathway" ]
[ "Developmental protein" ]
[ "Schizophrenia" ]
[ "Intermediate filaments", "Cytosol" ]
[]
[]
[]
Supported
null
null
178
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 20: Macrophages & Microglia - Immune response
Cluster 71: Lymphoma - Inflammatory response
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 46: Brain & retina - Neuronal signaling
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in single
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,689
9
ENSG00000162949
CAPN13
Calpain 13
[ "Q6MZZ7" ]
2
30722771-30820542
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA029496", "HPA029497", "HPA030034" ]
[ "FLJ23523" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Protease", "Thiol protease" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
null
Cluster 11: White matter - Signal transduction
Cluster 27: Breast cancer - Unknown function
Cluster 38: Secretory epithelial cells - Exocrine secretion
Cluster 77: Intestine - Digestion
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enriched
Detected in many
4
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
10,690
6
ENSG00000162951
LRRTM1
Leucine rich repeat transmembrane neuronal 1
[ "Q86UE6" ]
2
80288351-80304752
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA046607", "HPA062660" ]
[ "FLJ32082" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[ "Golgi apparatus" ]
[]
[]
[]
Approved
Approved
null
null
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 32: Non-specific - Cell proliferation
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 78: Brain - Neuronal signaling
Group enriched
Detected in some
5
Group enriched
Detected in some
6
Group enriched
Detected in many
9
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Glioblastoma Multiforme" ]
[ "Thyroid Carcinoma" ]
[ "Glioblastoma Multiforme", "Thyroid Carcinoma" ]
10,691
8
ENSG00000162959
MEMO1
Mediator of cell motility 1
[ "Q9Y316" ]
2
31865060-32011230
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA042603", "HPA057952" ]
[ "C2orf4", "CGI-27", "MEMO" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Approved
Approved
null
18
null
null
Cluster 25: Non-specific - Unknown function
Cluster 19: Astrocytes - Mixed function
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 22: Non-specific - Basic cellular functions
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
4
Low immune cell specificity
Detected in all
null
2
2
1
[ "Colon Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Colon Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
10,692
3
ENSG00000162961
DPY30
Dpy-30 histone methyltransferase complex regulatory subunit
[ "Q9C005" ]
2
31867809-32039805
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043761" ]
[ "Cps25", "HDPY-30", "Saf19" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Chromatin regulator" ]
[]
[ "Nucleoplasm" ]
[ "Golgi apparatus" ]
[]
[]
Supported
Supported
null
54
null
null
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 39: Astrocytes - Mixed function
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
10,693
1
ENSG00000162971
TYW5
TRNA-yW synthesizing protein 5
[ "A2RUC4" ]
2
199928913-199955736
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA045803" ]
[ "C2orf60", "FLJ37953" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "tRNA processing" ]
[ "Dioxygenase", "Oxidoreductase" ]
[]
[ "Mitochondria" ]
[]
[]
[]
Approved
Uncertain
null
1
null
null
null
Cluster 9: Non-specific - Receptor signaling
Cluster 56: Non-specific - Sensory perception
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
10,694
3
ENSG00000162972
MAIP1
Matrix AAA peptidase interacting protein 1
[ "Q8WWC4" ]
2
199955317-200008540
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA064013", "HPA072231" ]
[ "C2orf47", "DKFZp666A212", "FLJ22555" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Mitochondria" ]
[]
[]
[]
Supported
Approved
null
5
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 34: Non-specific - Mixed function
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,695
7
ENSG00000162975
KCNF1
Potassium voltage-gated channel modifier subfamily F member 1
[ "Q9H3M0" ]
2
10911934-10914225
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA014738", "HPA062278" ]
[ "IK8", "KCNF", "kH1", "Kv5.1" ]
[ "Plasma proteins", "Predicted membrane proteins", "Transporters", "Voltage-gated ion channels" ]
[ "Ion transport", "Potassium transport", "Transport" ]
[ "Ion channel", "Potassium channel", "Voltage-gated channel" ]
[]
[ "Golgi apparatus" ]
[ "Nucleoplasm", "Vesicles", "Primary cilium transition zone" ]
[]
[]
Approved
Enhanced
null
9
null
null
null
Cluster 23: Choroid plexus - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 78: Brain - Neuronal signaling
Group enriched
Detected in some
28
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in many
7
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,696
9
ENSG00000162976
SLC66A3
Solute carrier family 66 member 3
[ "Q8N755" ]
2
11155198-11178870
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA061607" ]
[ "C2orf22", "MGC33602", "PQLC3" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
null
null
null
null
null
Cluster 25: Non-specific - Unknown function
Cluster 21: Non-specific - Metabolism
Cluster 27: Breast cancer - Unknown function
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,697
8
ENSG00000162980
ARL5A
ADP ribosylation factor like GTPase 5A
[ "Q9Y689" ]
2
151788984-151828492
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA027002" ]
[ "ARL5" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Approved
null
2
null
null
Cluster 46: Basophils - Proteolysis
Cluster 21: Non-specific - Metabolism
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 74: Microglia - Neuroimmunity & neuroinflammation
Cluster 41: Striated muscle - Muscle contraction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in all
6
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,698
3
ENSG00000162981
LRATD1
LRAT domain containing 1
[ "Q96KN4" ]
2
14632700-14650814
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047703" ]
[ "FAM84A", "FLJ35392", "NSE1" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
null
3
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration
Cluster 17: Intestine - Digestion
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
4
0
4
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Rectum Adenocarcinoma" ]
10,699
4
ENSG00000162989
KCNJ3
Potassium inwardly rectifying channel subfamily J member 3
[ "P48549" ]
2
154697855-154858354
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA024231", "HPA064138" ]
[ "GIRK1", "KGA", "Kir3.1" ]
[ "FDA approved drug targets", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters", "Voltage-gated ion channels" ]
[ "Ion transport", "Potassium transport", "Transport" ]
[ "Ion channel", "Voltage-gated channel" ]
[ "FDA approved drug targets" ]
[ "Mitochondria" ]
[ "Plasma membrane" ]
[]
[]
Approved
Uncertain
null
2
null
null
null
Cluster 35: Non-specific - DNA binding
Cluster 10: Ciliated cells - Ion channel activity
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 27: Cerebellum - Synaptic function
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,700
6
ENSG00000162992
NEUROD1
Neuronal differentiation 1
[ "Q13562" ]
2
181668295-181680827
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA003278", "CAB022450" ]
[ "BETA2", "BHF-1", "bHLHa3", "MODY6", "NEUROD" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Differentiation", "Neurogenesis", "Transcription", "Transcription regulation" ]
[ "Activator", "Developmental protein", "DNA-binding" ]
[ "Diabetes mellitus", "Disease variant" ]
[]
[]
[]
[]
null
Approved
null
14
null
null
null
Cluster 35: Non-specific - DNA binding
Cluster 1: Neuronal - Visual perception
Cluster 96: Enteroendocrine cells - Neuropeptide signaling
Cluster 46: Brain & retina - Neuronal signaling
Group enriched
Detected in some
15
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
5
Group enriched
Detected in some
6
Low immune cell specificity
Detected in single
null
1
2
0
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
10,701
8
ENSG00000162994
CLHC1
Clathrin heavy chain linker domain containing 1
[ "Q8NHS4" ]
2
55172547-55232563
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA045418", "HPA053557" ]
[ "C2orf63", "FLJ31438" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoli fibrillar center", "Centrosome" ]
[]
[]
[]
Approved
Uncertain
null
2
null
null
Cluster 14: Non-specific - Unknown function
Cluster 17: Choroid plexus - Cilium
Cluster 56: Non-specific - Sensory perception
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 21: Testis - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in single
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,702
9
ENSG00000162998
FRZB
Frizzled related protein
[ "Q92765" ]
2
182833275-182866637
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FRE", "FRITZ", "FRP-3", "FRZB-1", "FRZB-PEN", "FRZB1", "FZRB", "hFIZ", "SFRP3", "SRFP3" ]
[ "Disease related genes", "Predicted secreted proteins" ]
[ "Differentiation", "Wnt signaling pathway" ]
[ "Developmental protein" ]
[ "Disease variant" ]
[]
[]
[ "Secreted in other tissues" ]
[ "Developmental protein" ]
null
null
null
1
null
null
null
Cluster 8: Immune cells - Immune response
Cluster 51: Myeloma - Immunoglobulins
Cluster 11: Muller glia cells - Retinal homeostasis
Cluster 48: Ciliated tissues - Cilium organization
Group enriched
Detected in many
5
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Group enriched
Detected in many
8
Not detected in immune cells
Not detected
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
10,703
2
ENSG00000162999
DUSP19
Dual specificity phosphatase 19
[ "Q8WTR2" ]
2
183078559-183100008
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA021501" ]
[ "DUSP17", "SKRP1" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Protein phosphatase" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Approved
null
7
Yes
No
Cluster 43: Non-specific - Transcription & Translation
Cluster 51: Neurons - Mixed function
Cluster 3: Rhabdoid - Membrane components
Cluster 97: Non-specific - Cellular respiration
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
0
0
0
[]
[]
[]
10,704
7
ENSG00000163001
CFAP36
Cilia and flagella associated protein 36
[ "Q96G28" ]
2
55519604-55545079
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA008994", "HPA017061" ]
[ "BARTL1", "CCDC104", "MGC15407" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Nucleoli fibrillar center", "Nuclear bodies", "Primary cilium", "Cytosol" ]
[]
[]
Approved
Approved
null
6
null
null
Cluster 11: T-cells - Unknown function
Cluster 23: Choroid plexus - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
4
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,705
5
ENSG00000163002
NUP35
Nucleoporin 35
[ "Q8NFH5" ]
2
183117513-183161680
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA018401", "HPA018410", "HPA018441" ]
[ "MP44" ]
[ "Essential proteins", "Metabolic proteins", "Predicted intracellular proteins", "Transporters" ]
[ "mRNA transport", "Protein transport", "Translocation", "Transport" ]
[]
[]
[ "Nucleoplasm", "Nuclear membrane" ]
[ "Plasma membrane" ]
[]
[]
Approved
Enhanced
null
45
No
No
Cluster 43: Non-specific - Transcription & Translation
Cluster 31: Non-specific - Transcription
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 57: Testis - Spermatogenesis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
4
Low immune cell specificity
Detected in many
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Prostate Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Prostate Adenocarcinoma" ]
10,706
5
ENSG00000163006
CCDC138
Coiled-coil domain containing 138
[ "Q96M89" ]
2
108786757-108885477
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049899", "HPA054223" ]
[ "FLJ32745" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
18
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 2: Neurons - Nucleosome
Cluster 59: Leukemia - T-cell receptor
Cluster 20: Non-specific - Transcription regulation
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
10,707
2
ENSG00000163012
ZSWIM2
Zinc finger SWIM-type containing 2
[ "Q8NEG5" ]
2
186827475-186849208
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "MEX", "MGC33890", "ZZZ2" ]
[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Apoptosis", "Ubl conjugation pathway" ]
[ "Transferase" ]
[]
[]
[]
[]
[]
null
null
null
1
null
null
null
null
Cluster 5: Rhabdoid - Unknown function
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 57: Testis - Spermatogenesis
Tissue enriched
Detected in single
13
Not detected
Not detected
null
Not detected
Not detected
null
Group enriched
Detected in some
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,708
7
ENSG00000163013
FBXO41
F-box protein 41
[ "Q8TF61" ]
2
73254682-73284478
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA055246", "HPA058386" ]
[ "Fbx41", "KIAA1940" ]
[ "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[]
[]
[ "Nucleoplasm", "Cytosol" ]
[ "Plasma membrane" ]
[]
[]
Approved
null
null
null
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 46: Lymphoma - Humoral immune response
Cluster 2: Cerebellar granular cells - Neuronal signaling
Cluster 10: Brain - Synaptic signal transduction
Tissue enriched
Detected in many
4
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
3
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
10,709
2
ENSG00000163017
ACTG2
Actin gamma 2, smooth muscle
[ "P63267" ]
2
73892314-73919865
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041264", "HPA041271" ]
[ "ACTA3", "ACTL3", "ACTSG" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Muscle protein" ]
[ "Disease variant" ]
[]
[]
[]
[]
null
Supported
null
4
null
null
Cluster 9: T-regs - Cell cycle regulation
Cluster 23: Choroid plexus - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 62: Smooth muscle cells - Muscle contraction
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in all
4
Group enriched
Detected in many
5
Immune cell enriched
Detected in single
11
2
0
2
[ "Bladder Urothelial Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
10,710
9
ENSG00000163026
WDCP
WD repeat and coiled coil containing
[ "Q9H6R7" ]
2
24029347-24049575
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041054" ]
[ "C2orf44", "FLJ21945", "MMAP" ]
[ "Cancer-related genes", "Disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Cancer-related genes" ]
[ "Nucleoli" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
22
null
null
Cluster 33: Non-specific - ATP binding
Cluster 55: Non-specific - Transcription
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 65: Non-specific - Cell growth & division
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
10,711
2
ENSG00000163029
SMC6
Structural maintenance of chromosomes 6
[ "Q96SB8" ]
2
17663812-17800242
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035057", "CAB037186", "HPA042733" ]
[ "FLJ22116", "SMC6L1" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA recombination", "DNA repair" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Uncertain
null
33
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 31: Non-specific - Transcription
Cluster 55: Lymphoma - Immune response
Cluster 99: Retinal pigment epithelial cells - Retinol metabolism
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
10,712
5
ENSG00000163032
VSNL1
Visinin like 1
[ "P62760" ]
2
17539126-17657018
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA053808" ]
[ "HLP3", "HPCAL3", "HUVISL1", "VILIP", "VILIP-1" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
null
null
13
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 32: Non-specific - Cell proliferation
Cluster 2: Cerebellar granular cells - Neuronal signaling
Cluster 10: Brain - Synaptic signal transduction
Tissue enriched
Detected in many
17
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
10,713
9
ENSG00000163040
CCDC74A
Coiled-coil domain containing 74A
[ "Q96AQ1" ]
2
131527675-131533666
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA046284" ]
[ "FLJ40345" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Centrosome", "Basal body" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
Approved
null
null
2
null
null
null
Cluster 17: Choroid plexus - Cilium
Cluster 11: Neuronal - Sensory perception
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 56: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[]
[ "Glioblastoma Multiforme", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
10,714
1
ENSG00000163041
H3-3A
H3.3 histone A
[ "P84243" ]
1
226061851-226072019
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB011481", "CAB037178", "HPA042570", "HPA050968", "HPA064058" ]
[ "H3.3A", "H3F3", "H3F3A" ]
[ "Cancer-related genes", "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[ "DNA-binding" ]
[ "Cancer-related genes", "Disease variant", "Intellectual disability" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Supported
null
178
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 55: Non-specific - Transcription
Cluster 45: Non-specific - Nuclear processes
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Immune cell enhanced
Detected in all
null
0
0
0
[]
[]
[]
10,715
9
ENSG00000163046
ANKRD30BL
Ankyrin repeat domain 30B like
[ "A7E2S9" ]
2
132147591-132257969
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA076167" ]
[ "ANKRD30BP3", "NCRNA00164" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Plasma membrane" ]
[]
[]
[]
Approved
null
null
null
null
null
null
null
Cluster 51: Myeloma - Immunoglobulins
Cluster 109: Neurons - Neuronal signaling
Cluster 79: Testis - Spermatogenesis
Tissue enriched
Detected in single
28
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,716
6
ENSG00000163050
COQ8A
Coenzyme Q8A
[ "Q8NI60" ]
1
226940286-226987544
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA061662" ]
[ "ADCK3", "CABC1", "COQ8", "SCAR9" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Ubiquinone biosynthesis" ]
[ "Kinase", "Transferase" ]
[ "Disease variant", "Neurodegeneration", "Primary mitochondrial disease" ]
[ "Mitochondria" ]
[]
[]
[]
Supported
null
null
44
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 50: Non-specific - Nucleic acid binding
Cluster 45: Non-specific - Nuclear processes
Cluster 102: Non-specific - Mixed function
Cluster 19: Skeletal muscle - Striated muscle contraction
Group enriched
Detected in many
7
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
10,717
6
ENSG00000163064
EN1
Engrailed homeobox 1
[ "Q05925" ]
2
118842171-118847648
Evidence at protein level
Evidence at protein level
No human protein/transcript evidence
Evidence at protein level
[ "CAB014884", "HPA073141" ]
[]
[ "Disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[]
[ "Developmental protein", "DNA-binding" ]
[ "Dwarfism" ]
[ "Nucleoli rim" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Enhanced
null
7
null
null
null
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 27: Breast cancer - Unknown function
Cluster 62: Smooth muscle cells - Muscle contraction
Cluster 25: Non-specific - Basic cellular processes
Group enriched
Detected in some
5
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Glioblastoma Multiforme", "Uterine Corpus Endometrial Carcinoma" ]
[ "Glioblastoma Multiforme", "Uterine Corpus Endometrial Carcinoma" ]
10,720
5
ENSG00000163069
SGCB
Sarcoglycan beta
[ "Q16585" ]
4
52020706-52038299
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA011422", "HPA058656" ]
[ "A3b", "LGMD2E", "SGC" ]
[ "Disease related genes", "Human disease related genes", "Predicted membrane proteins" ]
[]
[]
[ "Disease variant", "Limb-girdle muscular dystrophy" ]
[ "Cytosol" ]
[]
[]
[]
Approved
Enhanced
null
32
null
null
Cluster 16: Non-specific - Cell proliferation
Cluster 28: Oligodendrocytes - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,721
7
ENSG00000163071
SPATA18
Spermatogenesis associated 18
[ "Q8TC71" ]
4
52051304-52097299
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036854", "HPA036855" ]
[ "FLJ32906" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Mitochondria" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
Supported
Enhanced
null
17
null
null
null
Cluster 3: Choroid plexus - Cilium
Cluster 40: Non-specific - Unknown function
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 56: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enriched
Detected in many
5
Not detected in immune cells
Not detected
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,722
5
ENSG00000163072
NOSTRIN
Nitric oxide synthase trafficking
[ "Q8IVI9" ]
2
168786539-168865514
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044384", "HPA076885" ]
[ "MGC20702" ]
[ "Predicted intracellular proteins" ]
[ "Endocytosis" ]
[]
[]
[ "Cytosol" ]
[ "Vesicles" ]
[]
[]
Approved
Approved
null
5
null
null
null
Cluster 47: Endothelial cells - Vasculature
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,723
2
ENSG00000163075
CFAP221
Cilia and flagella associated protein 221
[ "Q4G0U5" ]
2
119544432-119662251
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042501", "HPA054164" ]
[ "FAP221", "PCDP1" ]
[ "Predicted intracellular proteins" ]
[ "Cilium biogenesis/degradation" ]
[ "Calmodulin-binding" ]
[]
[ "Primary cilium", "Primary cilium tip", "Connecting piece", "Flagellar centriole" ]
[]
[]
[]
Supported
null
null
null
null
null
null
Cluster 17: Choroid plexus - Cilium
Cluster 15: Kidney cancer - Membrane components
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 56: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
10,724
9
ENSG00000163082
SGPP2
Sphingosine-1-phosphate phosphatase 2
[ "Q8IWX5" ]
2
222424543-222562621
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FLJ39004", "SPP2" ]
[ "Metabolic proteins", "Predicted membrane proteins" ]
[ "Lipid metabolism" ]
[ "Hydrolase" ]
[]
[]
[]
[]
[]
null
null
null
2
null
null
null
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 55: Lymphoma - Immune response
Cluster 51: Secretory epithelial cells - Mixed function
Cluster 69: Parathyroid gland - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,725
8
ENSG00000163083
INHBB
Inhibin subunit beta B
[ "P09529" ]
2
120346136-120351803
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA079405" ]
[]
[ "Cancer-related genes", "Predicted secreted proteins" ]
[]
[ "Growth factor", "Hormone" ]
[ "Cancer-related genes" ]
[ "Vesicles" ]
[]
[ "Secreted to blood" ]
[ "Hormone" ]
Approved
null
null
2
null
null
null
Cluster 19: Astrocytes - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Glioblastoma Multiforme", "Stomach Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Stomach Adenocarcinoma" ]
10,726
5
ENSG00000163092
XIRP2
Xin actin binding repeat containing 2
[ "A4UGR9" ]
2
166888480-167259753
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA034813", "HPA074599" ]
[ "CMYA3" ]
[ "Cancer-related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Actin-binding" ]
[ "Cancer-related genes" ]
[ "Plasma membrane" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Enhanced
null
6
null
null
null
null
Cluster 33: Sarcoma - Muscle contraction
Cluster 46: Skeletal myocytes - Muscle structure & formation
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Cancer enriched
Detected in some
5
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,727
6
ENSG00000163093
BBS5
Bardet-Biedl syndrome 5
[ "Q8N3I7" ]
2
169479480-169506655
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046125" ]
[ "DKFZp762I194" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Cilium biogenesis/degradation", "Protein transport", "Sensory transduction", "Transport", "Vision" ]
[]
[ "Bardet-Biedl syndrome", "Ciliopathy", "Disease variant", "Intellectual disability", "Obesity" ]
[ "Basal body", "Cytosol", "Acrosome" ]
[ "Primary cilium", "Perinuclear theca" ]
[]
[]
Supported
Uncertain
null
26
null
null
null
Cluster 46: Brainstem - Mixed function
Cluster 69: Skin cancer - ECM organization
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
10,728
1
ENSG00000163104
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
[ "Q9H4L7" ]
4
94207611-94291292
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA016737" ]
[ "DKFZP762K2015", "ETL1", "KIAA1122" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair" ]
[ "Chromatin regulator", "DNA-binding", "Helicase", "Hydrolase" ]
[ "Ectodermal dysplasia", "Palmoplantar keratoderma" ]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Approved
null
29
null
null
Cluster 16: Non-specific - Cell proliferation
Cluster 31: Non-specific - Transcription
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 7: Non-specific - Transcription
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,729
7
ENSG00000163106
HPGDS
Hematopoietic prostaglandin D synthase
[ "O60760" ]
4
94298535-94342876
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA024035" ]
[ "GSTS", "GSTS1", "GSTS1-1", "H-PGDS", "PGD2", "PGDS" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Fatty acid biosynthesis", "Fatty acid metabolism", "Lipid biosynthesis", "Lipid metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism" ]
[ "Isomerase", "Transferase" ]
[]
[ "Vesicles", "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Enhanced
null
5
null
null
Cluster 46: Basophils - Proteolysis
Cluster 20: Macrophages & Microglia - Immune response
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 58: Mast cells - Allergic inflammatory responses
Cluster 43: Placenta - Pregnancy hormone signaling
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in single
32
Low cancer specificity
Detected in many
null
Group enriched
Detected in some
14
Immune cell enriched
Detected in single
28
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
10,730
1
ENSG00000163110
PDLIM5
PDZ and LIM domain 5
[ "Q96HC4" ]
4
94451857-94668227
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB013511", "HPA016740", "HPA020026" ]
[ "Enh", "LIM" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Plasma membrane" ]
[ "Nucleoplasm", "Focal adhesion sites" ]
[]
[]
Approved
Enhanced
null
27
null
null
Cluster 32: Basophils - Transcription
Cluster 8: Immune cells - Immune response
Cluster 64: Connective tissue cells - ECM organization
Cluster 55: Myocytes - Oxidative muscle function
Cluster 62: Skeletal muscle - Muscle contraction
Group enriched
Detected in all
7
Low cancer specificity
Detected in all
null
Cancer enriched
Detected in all
7
Cell type enhanced
Detected in all
null
Immune cell enriched
Detected in all
5
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
10,731
6
ENSG00000163116
STPG2
Sperm tail PG-rich repeat containing 2
[ "Q8N412" ]
4
97184093-98143476
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA059473" ]
[ "C4orf37", "MGC46496" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Principal piece" ]
[]
[]
[]
Approved
null
null
null
null
null
null
Cluster 28: Oligodendrocytes - Mixed function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 50: Renal epithelial cells - Ion transport and pH regulation
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in single
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,733
3
ENSG00000163121
NEURL3
Neuralized E3 ubiquitin protein ligase 3
[ "Q96EH8" ]
2
96497646-96508109
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "Lincr", "LOC93082", "RNF132" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Host-virus interaction", "Immunity", "Innate immunity", "Ubl conjugation pathway" ]
[ "Transferase" ]
[]
[]
[]
[]
[]
null
null
null
4
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 38: Secretory epithelial cells - Exocrine secretion
Cluster 8: Pancreas - Proteolysis
Group enriched
Detected in some
5
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
10,734
7
ENSG00000163125
RPRD2
Regulation of nuclear pre-mRNA domain containing 2
[ "Q5VT52" ]
1
150363091-150476566
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA061693" ]
[ "FLJ32145", "HSPC099", "KIAA0460" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Vesicles" ]
[]
[]
[]
Approved
Approved
null
26
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 31: Non-specific - Transcription
Cluster 45: Non-specific - Nuclear processes
Cluster 7: Non-specific - Transcription
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in many
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,735
3
ENSG00000163131
CTSS
Cathepsin S
[ "P25774" ]
1
150730079-150765957
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB000460", "HPA002988" ]
[]
[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Protease", "Thiol protease" ]
[]
[ "Vesicles" ]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Approved
Supported
null
75
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 20: Macrophages & Microglia - Immune response
Cluster 49: HMC-1 - Innate immune response
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
4
0
4
[ "Bladder Urothelial Carcinoma", "Colon Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Lung Squamous Cell Carcinoma" ]
[ "Bladder Urothelial Carcinoma", "Colon Adenocarcinoma", "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
10,737
7
ENSG00000163132
MSX1
Msh homeobox 1
[ "P28360" ]
4
4859665-4863936
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB026198", "HPA063895", "HPA073604" ]
[ "HOX7", "HYD1", "OFC5" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Developmental protein", "DNA-binding", "Repressor" ]
[ "Disease variant", "Ectodermal dysplasia" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Enhanced
null
4
null
null
null
Cluster 36: Choroid plexus - Mixed function
Cluster 32: Non-specific - Cell proliferation
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 1: Choroid plexus - Transmembrane transport
Group enriched
Detected in many
5
Cancer enhanced
Detected in many
null
Cancer enriched
Detected in all
16
Group enriched
Detected in many
4
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,738
6
ENSG00000163138
PACRGL
Parkin coregulated like
[ "Q8N7B6" ]
4
20696282-20752907
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA054666" ]
[ "C4orf28", "MGC29898" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Vesicles" ]
[]
[]
[]
Approved
null
null
6
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 17: Choroid plexus - Cilium
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 7: Non-specific - Transcription
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
10,739
3
ENSG00000163141
BNIPL
BCL2 interacting protein like
[ "Q7Z465" ]
1
151036321-151047720
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA019946" ]
[ "BNIP-S", "BNIP-Salpha", "BNIP-Sbeta", "BNIPl-1", "BNIPL-2", "PP753" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Apoptosis" ]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Uncertain
null
null
3
null
null
null
Cluster 15: Non-specific - Transcription
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 58: Skin - Keratinization
Group enriched
Detected in many
5
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in many
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,740
5
ENSG00000163145
C1QTNF7
C1q and TNF related 7
[ "Q9BXJ2" ]
4
15339818-15446167
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "CAB007055", "HPA051797", "HPA055392" ]
[ "CTRP7" ]
[ "Plasma proteins", "Predicted secreted proteins" ]
[]
[]
[]
[ "Vesicles" ]
[]
[ "Secreted to blood" ]
[ "Complement pathway" ]
Approved
Uncertain
null
null
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 44: Connective tissue cells - ECM organization
Cluster 89: Adipocytes - Lipid metabolism
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in many
null
Not detected
Not detected
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,741
4
ENSG00000163154
TNFAIP8L2
TNF alpha induced protein 8 like 2
[ "Q6P589" ]
1
151156649-151159749
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA062742" ]
[ "FLJ23467" ]
[ "Predicted intracellular proteins" ]
[ "Immunity", "Innate immunity" ]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Approved
null
null
2
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 20: Macrophages & Microglia - Immune response
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in many
null
Group enriched
Detected in some
7
Low cancer specificity
Detected in all
null
Not detected
Not detected
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Breast Invasive Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Lung Adenocarcinoma" ]
10,742
1
ENSG00000163155
LYSMD1
LysM domain containing 1
[ "Q96S90" ]
1
151159748-151165948
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA028055", "HPA064537" ]
[ "MGC35223", "RP11-68I18.5", "SB145" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Uncertain
null
11
null
null
Cluster 41: Basophils - Unknown function
Cluster 16: Non-specific - Transcription
Cluster 45: Non-specific - Nuclear processes
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
10,743
9
ENSG00000163156
SCNM1
Sodium channel modifier 1
[ "Q9BWG6" ]
1
151156664-151170296
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA052439", "HPA054324" ]
[ "MGC3180" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing" ]
[]
[ "Ciliopathy", "Disease variant" ]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
null
156
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 28: Oligodendrocytes - Mixed function
Cluster 45: Non-specific - Nuclear processes
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Glioblastoma Multiforme", "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
10,744
9
ENSG00000163157
TMOD4
Tropomodulin 4
[ "Q9NZQ9" ]
1
151169986-151176284
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA028203" ]
[ "Sk-Tmod" ]
[ "Predicted intracellular proteins" ]
[]
[ "Actin-binding" ]
[]
[]
[]
[]
[]
null
Enhanced
null
5
null
null
Cluster 30: Non-specific - DNA binding
Cluster 42: Choroid plexus - Mitochondria
Cluster 45: Non-specific - Nuclear processes
Cluster 36: Skeletal myocytes - Muscle excitation & contraction
Cluster 19: Skeletal muscle - Striated muscle contraction
Group enriched
Detected in many
67
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in some
null
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
1
0
1
[ "Breast Invasive Carcinoma" ]
[]
[ "Breast Invasive Carcinoma" ]
10,745
1
ENSG00000163159
VPS72
Vacuolar protein sorting 72 homolog
[ "Q15906" ]
1
151176304-151195321
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA065709" ]
[ "Swc2", "TCFL1", "YL-1", "YL1" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Chromatin regulator", "DNA-binding" ]
[]
[ "Nuclear speckles" ]
[]
[]
[]
Supported
null
null
54
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 28: Oligodendrocytes - Mixed function
Cluster 45: Non-specific - Nuclear processes
Cluster 97: Non-specific - Cellular respiration
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Glioblastoma Multiforme" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma" ]
10,746
3
ENSG00000163161
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit
[ "P19447" ]
2
127257290-127294166
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB037153", "HPA046077" ]
[ "BTF2", "RAD25", "Ssl2", "XPB" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair", "Host-virus interaction", "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Helicase", "Hydrolase", "Isomerase" ]
[ "Cancer-related genes", "Cockayne syndrome", "Deafness", "Disease variant", "Dwarfism", "Ichthyosis", "Xeroderma pigmentosum" ]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Supported
Approved
null
92
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 23: Choroid plexus - Mixed function
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 7: Non-specific - Transcription
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
10,747
9
ENSG00000163162
RNF149
Ring finger protein 149
[ "Q8NC42" ]
2
101271219-101308701
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA011424" ]
[ "FLJ90504" ]
[ "Enzymes", "Metabolic proteins", "Predicted membrane proteins" ]
[ "Ubl conjugation pathway" ]
[ "Transferase" ]
[]
[ "Vesicles", "Plasma membrane" ]
[]
[]
[]
Approved
Approved
null
50
null
null
Cluster 28: Neutrophils - Unknown function
Cluster 20: Macrophages & Microglia - Immune response
Cluster 15: Kidney cancer - Membrane components
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in all
5
Immune cell enriched
Detected in all
5
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
10,748
2
ENSG00000163166
IWS1
Interacts with SUPT6H, CTD assembly factor 1
[ "Q96ST2" ]
2
127436207-127526886
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035719", "HPA061866" ]
[ "DKFZp761G0123", "FLJ10006", "FLJ14655", "FLJ32319" ]
[ "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing", "mRNA transport", "Transcription", "Transcription regulation", "Transport" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Supported
null
18
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 11: White matter - Signal transduction
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 51: Secretory epithelial cells - Mixed function
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
10,749
2
ENSG00000163170
BOLA3
BolA family member 3
[ "Q53S33" ]
2
74135400-74147912
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046393", "HPA053162" ]
[]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant", "Primary mitochondrial disease" ]
[ "Nuclear bodies", "Mitochondria" ]
[ "Cytosol" ]
[]
[]
Supported
Uncertain
null
11
null
null
Cluster 11: T-cells - Unknown function
Cluster 45: Non-specific - Mixed function
Cluster 7: Liver cancer - Metabolism
Cluster 97: Non-specific - Cellular respiration
Cluster 52: Non-specific - Cellular respiration
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
2
2
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
10,750
3
ENSG00000163171
CDC42EP3
CDC42 effector protein 3
[ "Q9UKI2" ]
2
37641882-37738468
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA034986", "HPA061792" ]
[ "BORG2", "CEP3", "UB1" ]
[ "Predicted intracellular proteins" ]
[ "Cell shape" ]
[]
[]
[ "Plasma membrane", "Actin filaments" ]
[]
[]
[]
Supported
Approved
null
4
null
null
Cluster 28: Neutrophils - Unknown function
Cluster 23: Choroid plexus - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,751
1
ENSG00000163191
S100A11
S100 calcium binding protein A11
[ "P31949" ]
1
152032506-152047907
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB034320", "HPA042745" ]
[ "S100C" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Cytosol" ]
[ "Nuclear speckles" ]
[]
[]
Supported
Enhanced
null
13
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 20: Macrophages & Microglia - Immune response
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
3
2
2
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,752
3
ENSG00000163206
SMCP
Sperm mitochondria associated cysteine rich protein
[ "P49901" ]
1
152878322-152885047
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035105", "HPA077113" ]
[ "MCSP" ]
[ "Predicted intracellular proteins" ]
[ "Fertilization" ]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
70
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 23: Testis - Spermatogenesis
Tissue enriched
Detected in some
576
Not detected
Not detected
null
Cancer enhanced
Detected in single
null
Cell type enriched
Detected in some
6
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,754
6
ENSG00000163207
IVL
Involucrin
[ "P07476" ]
1
152908546-152911886
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002243", "HPA055211" ]
[]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Keratinization" ]
[]
[]
[ "Cytosol" ]
[ "Nuclear bodies", "Centrosome" ]
[]
[]
Supported
Enhanced
null
33
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 81: Squamous epithelium - Keratinization
Group enriched
Detected in some
6
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
4
Group enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,755
1
ENSG00000163209
SPRR3
Small proline rich protein 3
[ "Q9UBC9" ]
1
153001747-153003856
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044467" ]
[]
[ "Cancer-related genes", "Predicted intracellular proteins" ]
[ "Keratinization" ]
[]
[ "Cancer-related genes" ]
[]
[]
[]
[]
null
Enhanced
null
6
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 84: Apical squamous epithelium - Cornification
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enriched
Detected in some
11
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
10,756
2
ENSG00000163214
DHX57
DExH-box helicase 57
[ "Q6P158" ]
2
38797729-38875934
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA036160", "HPA036161" ]
[ "DDX57" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Helicase", "Hydrolase" ]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
52
null
null
Cluster 14: Non-specific - Unknown function
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 21: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
4
Low immune cell specificity
Detected in many
null
1
2
0
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
10,757
3
ENSG00000163216
SPRR2D
Small proline rich protein 2D
[ "P22532" ]
1
153039732-153041931
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[]
[ "Predicted intracellular proteins" ]
[ "Keratinization" ]
[]
[]
[]
[]
[]
[]
null
null
null
2
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cancer enriched
Detected in many
5
Cell type enriched
Detected in some
14
Not detected in immune cells
Not detected
null
1
2
0
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
10,758
8
ENSG00000163217
BMP10
Bone morphogenetic protein 10
[ "O95393" ]
2
68860909-68871397
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[]
[ "Predicted secreted proteins" ]
[ "Cell adhesion" ]
[ "Cytokine", "Developmental protein", "Growth factor" ]
[ "Disease variant" ]
[]
[]
[ "Secreted to blood" ]
[ "Cytokine" ]
null
null
null
51
null
null
null
null
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 35: Non-specific - Mixed function
Tissue enriched
Detected in some
118
Group enriched
Detected in some
27
Not detected
Not detected
null
Cell type enriched
Detected in some
6
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,759
7
ENSG00000163218
PGLYRP4
Peptidoglycan recognition protein 4
[ "Q96LB8" ]
1
153330120-153348841
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB025879" ]
[ "PGLYRPIbeta", "PGRP-Ibeta", "PGRPIB", "SBBI67" ]
[ "Metabolic proteins", "Predicted secreted proteins" ]
[ "Immunity", "Innate immunity" ]
[ "Antibiotic", "Antimicrobial" ]
[]
[ "Vesicles", "Plasma membrane" ]
[]
[ "Secreted in other tissues" ]
[ "Immunity" ]
Approved
null
null
null
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 58: Skin - Keratinization
Group enriched
Detected in some
5
Cancer enriched
Detected in single
10
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,760
3
ENSG00000163219
ARHGAP25
Rho GTPase activating protein 25
[ "P42331" ]
2
68679601-68826833
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035346", "HPA061395" ]
[ "KIAA0053" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "GTPase activation" ]
[]
[ "Nucleoplasm", "Vesicles" ]
[]
[]
[]
Approved
Enhanced
null
2
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 20: Macrophages & Microglia - Immune response
Cluster 55: Lymphoma - Immune response
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
1
0
1
[ "Lung Adenocarcinoma" ]
[]
[ "Lung Adenocarcinoma" ]
10,761
9
ENSG00000163220
S100A9
S100 calcium binding protein A9
[ "P06702" ]
1
153357854-153361023
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA004193", "CAB009441", "CAB080262" ]
[ "60B8AG", "CAGB", "CFAG", "CGLB", "LIAG", "MAC387", "MIF", "MRP-14", "MRP14", "NIF", "P14", "S100-A9" ]
[ "Cancer-related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Apoptosis", "Autophagy", "Chemotaxis", "Immunity", "Inflammatory response", "Innate immunity" ]
[ "Antimicrobial", "Antioxidant" ]
[ "Cancer-related genes" ]
[ "Plasma membrane", "Intermediate filaments", "Cytosol" ]
[]
[ "Secreted to blood" ]
[ "Immunity" ]
Supported
Enhanced
null
44
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 12: Non-specific - Vasculature
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 11: Esophagus - Basic cellular processes
Group enriched
Detected in all
4
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enriched
Detected in many
4
Group enriched
Detected in all
6
3
0
3
[]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]
10,762
1
ENSG00000163221
S100A12
S100 calcium binding protein A12
[ "P80511" ]
1
153373711-153375621
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA002881", "CAB025872" ]
[ "CAAF1", "CAGC", "CGRP", "ENRAGE", "MRP6", "p6" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Immunity", "Inflammatory response", "Innate immunity" ]
[ "Antibiotic", "Antimicrobial", "Fungicide" ]
[]
[]
[]
[ "Secreted to blood" ]
[ "Immunity" ]
null
Enhanced
null
1
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 12: Non-specific - Vasculature
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 15: Bone marrow - Innate immune response
Tissue enriched
Detected in many
6
Group enriched
Detected in some
5
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Group enriched
Detected in many
13
1
0
1
[]
[ "Stomach Adenocarcinoma" ]
[ "Stomach Adenocarcinoma" ]
10,763
3
ENSG00000163235
TGFA
Transforming growth factor alpha
[ "P01135" ]
2
70447284-70554193
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA042297" ]
[]
[ "Cancer-related genes", "Human disease related genes", "Plasma proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins" ]
[]
[ "Growth factor", "Mitogen" ]
[ "Cancer-related genes" ]
[ "Vesicles" ]
[]
[ "Secreted to blood" ]
[ "Growth factor" ]
Approved
Approved
null
10
No
No
Cluster 21: Neutrophils - Unknown function
Cluster 30: White matter - Myelination
Cluster 15: Kidney cancer - Membrane components
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 3: Oligodendrocytes - Myelination
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
4
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
10,764
3
ENSG00000163239
TDRD10
Tudor domain containing 10
[ "Q5VZ19" ]
1
154502219-154548147
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA054327" ]
[ "DKFZp434M202" ]
[ "Cancer-related genes", "Predicted intracellular proteins" ]
[]
[ "RNA-binding" ]
[ "Cancer-related genes" ]
[ "Vesicles" ]
[]
[]
[]
Approved
null
null
null
null
null
null
Cluster 47: Endothelial cells - Vasculature
Cluster 4: Non-specific - Transcription
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 79: Testis - Spermatogenesis
Tissue enriched
Detected in many
5
Cancer enhanced
Detected in single
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Lung Adenocarcinoma" ]
[]
[ "Lung Adenocarcinoma" ]
10,765
5
ENSG00000163249
CCNYL1
Cyclin Y like 1
[ "Q8N7R7" ]
2
207711540-207761839
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046825" ]
[ "FLJ40432" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation", "Neurogenesis", "Spermatogenesis" ]
[ "Cyclin" ]
[]
[ "Plasma membrane" ]
[]
[]
[]
Supported
Approved
null
6
Yes
No
Cluster 20: Non-specific - DNA binding
Cluster 53: Neurons - Mixed function
Cluster 3: Rhabdoid - Membrane components
Cluster 20: Non-specific - Transcription regulation
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
10,766
2
ENSG00000163251
FZD5
Frizzled class receptor 5
[ "Q13467" ]
2
207762598-207769906
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA052361" ]
[ "C2orf31", "DKFZP434E2135", "HFZ5" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Wnt signaling pathway" ]
[ "Developmental protein", "G-protein coupled receptor", "Receptor", "Transducer" ]
[ "Microphthalmia" ]
[]
[]
[]
[]
null
Approved
null
3
null
null
null
Cluster 11: White matter - Signal transduction
Cluster 18: Liver cancer - Metabolism
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 77: Intestine - Digestion
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,767
7
ENSG00000163254
CRYGC
Crystallin gamma C
[ "P07315" ]
2
208128137-208129828
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043386" ]
[ "CRYG3" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[ "Eye lens protein" ]
[ "Cataract", "Disease variant" ]
[ "Vesicles", "Cytosol" ]
[]
[]
[]
Approved
Supported
null
11
null
null
null
null
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 79: Testis - Spermatogenesis
Tissue enriched
Detected in single
13
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,768
1
ENSG00000163257
DCAF16
DDB1 and CUL4 associated factor 16
[ "Q9NXF7" ]
4
17800655-17810758
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA042487" ]
[ "C4orf30", "FLJ20280" ]
[ "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[]
[]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
12
null
null
Cluster 24: Non-specific - Transcription
Cluster 28: Oligodendrocytes - Mixed function
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 7: Non-specific - Transcription
Cluster 54: Non-specific - Ribosome
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,769
8
ENSG00000163263
CFAP141
Cilia and flagella associated protein 141
[ "Q5VU69" ]
1
154199085-154206333
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "C1orf189" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
4
null
null
null
Cluster 46: Brainstem - Mixed function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 56: Ciliated tissues - Cilium organization
Group enriched
Detected in some
12
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
4
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
10,770
9
ENSG00000163273
NPPC
Natriuretic peptide C
[ "P23582" ]
2
231921809-231926396
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA035362" ]
[ "CNP" ]
[ "Predicted secreted proteins", "Transporters" ]
[ "Osteogenesis" ]
[ "Hormone", "Vasoactive" ]
[]
[]
[]
[ "Secreted to blood" ]
[ "Hormone" ]
null
Uncertain
null
2
null
null
null
Cluster 43: Hindbrain - Mixed function
Cluster 69: Skin cancer - ECM organization
Cluster 109: Neurons - Neuronal signaling
Cluster 3: Oligodendrocytes - Myelination
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Lung Squamous Cell Carcinoma" ]
[]
[ "Lung Squamous Cell Carcinoma" ]
10,771
2
ENSG00000163281
GNPDA2
Glucosamine-6-phosphate deaminase 2
[ "Q8TDQ7" ]
4
44682200-44726588
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000499", "HPA046891" ]
[ "SB52" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Carbohydrate metabolism" ]
[ "Hydrolase", "Isomerase" ]
[]
[ "Vesicles" ]
[ "Golgi apparatus" ]
[]
[]
Approved
Uncertain
null
7
null
null
Cluster 1: T-cells - Unknown function
Cluster 2: Neurons - Nucleosome
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 65: Brain - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
10,772
9
ENSG00000163283
ALPP
Alkaline phosphatase, placental
[ "P05187" ]
2
232378724-232382889
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB026327", "HPA038764", "HPA038765", "HPA051699" ]
[ "PALP", "PLAP" ]
[ "Cancer-related genes", "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Hydrolase" ]
[ "Cancer-related genes" ]
[ "Plasma membrane" ]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Approved
Enhanced
null
57
null
null
null
Cluster 48: Non-specific - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 81: Alveolar cells - Lung function
Cluster 43: Placenta - Pregnancy hormone signaling
Group enriched
Detected in some
6
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in some
6
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
10,773
8
ENSG00000163285
GABRG1
Gamma-aminobutyric acid type A receptor subunit gamma1
[ "Q8N1C3" ]
4
46035769-46124054
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035622", "HPA058102" ]
[]
[ "FDA approved drug targets", "Predicted membrane proteins" ]
[ "Ion transport", "Transport" ]
[ "Chloride channel", "Ion channel" ]
[ "FDA approved drug targets" ]
[ "Plasma membrane" ]
[ "Vesicles" ]
[]
[]
Supported
Approved
null
1
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 11: Neuronal - Sensory perception
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 78: Brain - Neuronal signaling
Tissue enriched
Detected in some
7
Group enriched
Detected in some
5
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,774
8
ENSG00000163286
ALPG
Alkaline phosphatase, germ cell
[ "P10696" ]
2
232406844-232410714
Evidence at protein level
No human protein/transcript evidence
Evidence at protein level
Evidence at protein level
[ "CAB020698", "HPA038764", "HPA038765", "HPA051699" ]
[ "ALPPL2", "GCAP" ]
[ "Enzymes", "FDA approved drug targets", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Hydrolase" ]
[ "FDA approved drug targets" ]
[ "Plasma membrane" ]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Approved
Approved
null
13
null
null
null
null
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
null
Not detected
Not detected
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
10,775
4
ENSG00000163288
GABRB1
Gamma-aminobutyric acid type A receptor subunit beta1
[ "P18505" ]
4
46993723-47426447
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[]
[ "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Ion transport", "Transport" ]
[ "Chloride channel", "Ion channel", "Ligand-gated ion channel", "Receptor" ]
[ "Disease variant", "Epilepsy", "FDA approved drug targets" ]
[]
[]
[]
[]
null
null
null
1
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 28: Astrocytes - Homeostasis & neuron support
Cluster 73: Brain - Neuronal signaling
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Cancer enriched
Detected in single
6
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,776
2
ENSG00000163291
PAQR3
Progestin and adipoQ receptor family member 3
[ "Q6TCH7" ]
4
78887127-78939438
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
6
null
null
null
Cluster 2: Neurons - Nucleosome
Cluster 30: Non-specific - Gene expression regulation
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in some
null
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,777
9
ENSG00000163293
NIPAL1
NIPA like domain containing 1
[ "Q6NVV3" ]
4
47914142-48040173
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA036765" ]
[ "DKFZp686A06115", "NPAL1", "SLC57A3" ]
[ "Predicted membrane proteins" ]
[ "Ion transport", "Transport" ]
[]
[]
[ "Golgi apparatus" ]
[]
[]
[]
Approved
Uncertain
null
18
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 11: Esophagus - Basic cellular processes
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Lung Adenocarcinoma" ]
[ "Lung Adenocarcinoma" ]
10,778
4
ENSG00000163295
ALPI
Alkaline phosphatase, intestinal
[ "P09923" ]
2
232456125-232460753
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038764", "HPA038765", "HPA051699" ]
[ "IAP" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Hydrolase" ]
[]
[ "Plasma membrane" ]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Approved
Supported
null
36
null
null
null
null
Cluster 34: Testis cancer - Unknown function
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 7: Small intestine - Absorption and Digestion
Tissue enriched
Detected in single
139
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Cell type enriched
Detected in some
11
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,779
7
ENSG00000163297
ANTXR2
ANTXR cell adhesion molecule 2
[ "P58335" ]
4
79901146-80125454
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "CMG-2", "CMG2", "FLJ31074" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Receptor" ]
[ "Disease variant" ]
[]
[]
[ "Intracellular and membrane" ]
[ "Receptor" ]
null
null
null
2
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 39: Astrocytes - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,780
2
ENSG00000163312
HELQ
Helicase, POLQ like
[ "Q8TDG4" ]
4
83407343-83455855
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036852", "HPA036853" ]
[ "Hel308" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair" ]
[ "DNA-binding", "Helicase", "Hydrolase", "Isomerase" ]
[]
[ "Nuclear speckles" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Approved
null
7
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 50: Non-specific - Nucleic acid binding
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 4: Adrenal gland - Steroid metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,781
1
ENSG00000163319
MRPS18C
Mitochondrial ribosomal protein S18C
[ "Q9Y3D5" ]
4
83455932-83469735
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA050404" ]
[ "CGI-134", "FLJ11146", "FLJ22967", "MRPS18-1" ]
[ "Predicted intracellular proteins", "Ribosomal proteins" ]
[]
[ "Ribonucleoprotein", "Ribosomal protein" ]
[]
[]
[]
[]
[]
null
Approved
null
72
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 55: Non-specific - Transcription
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 97: Non-specific - Cellular respiration
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
10,782
4
ENSG00000163320
CGGBP1
CGG triplet repeat binding protein 1
[ "Q9UFW8" ]
3
88051944-88149885
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035568", "HPA037017" ]
[ "CGGBP", "p20-CGGBP" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Supported
null
18
null
null
Cluster 32: Basophils - Transcription
Cluster 55: Non-specific - Transcription
Cluster 13: Non-specific - Mixed function
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 80: Thymus - Adaptive immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,783
1
ENSG00000163322
ABRAXAS1
Abraxas 1, BRCA1 A complex subunit
[ "Q6UWZ7" ]
4
83459517-83523348
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA037654" ]
[ "ABRA1", "ABRAXAS", "CCDC98", "FAM175A", "FLJ13614" ]
[ "Disease related genes", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair" ]
[ "Chromatin regulator" ]
[ "Disease variant" ]
[ "Nuclear bodies" ]
[]
[]
[]
Supported
Uncertain
null
17
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 48: Non-specific - Mixed function
Cluster 25: Non-specific - Ribosome
Cluster 106: Spermatogonia - Spermatogonial differentiation
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,784
7
ENSG00000163328
GPR155
G protein-coupled receptor 155
[ "Q7Z3F1" ]
2
174431571-174487094
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA036159", "HPA057384" ]
[ "DEP.7", "DEPDC3", "FLJ31819", "PGR22" ]
[ "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[]
[]
[]
[]
null
Approved
null
1
null
null
Cluster 33: Non-specific - ATP binding
Cluster 23: Choroid plexus - Mixed function
Cluster 32: Non-specific - Cell proliferation
Cluster 101: Choroid plexus epithelial cells - Ion transport
Cluster 1: Choroid plexus - Transmembrane transport
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
10,785
3
ENSG00000163331
DAPL1
Death associated protein like 1
[ "A0PJW8" ]
2
158795317-158862781
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046937", "HPA058635" ]
[]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Apoptosis", "Differentiation" ]
[]
[]
[ "Nucleoplasm", "Nuclear bodies", "Microtubules" ]
[]
[]
[]
Approved
Enhanced
null
4
null
null
Cluster 29: Non-specific - Unknown function
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 60: Prostate cancer - Unknown function
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 58: Skin - Keratinization
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in many
11
Group enriched
Detected in all
8
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
2
0
2
[ "Breast Invasive Carcinoma", "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
10,786
9
ENSG00000163344
PMVK
Phosphomevalonate kinase
[ "Q15126" ]
1
154924740-154936719
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA029900" ]
[ "HUMPMKI", "PMK", "PMKA" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Cholesterol biosynthesis", "Cholesterol metabolism", "Lipid biosynthesis", "Lipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism" ]
[ "Kinase", "Transferase" ]
[ "Disease variant" ]
[]
[]
[]
[]
null
Approved
null
27
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 19: Astrocytes - Mixed function
Cluster 45: Non-specific - Nuclear processes
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 1: Choroid plexus - Transmembrane transport
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,787
4
ENSG00000163346
PBXIP1
PBX homeobox interacting protein 1
[ "Q96AQ6" ]
1
154944076-154956123
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006949", "HPA073481" ]
[ "HPIP" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
27
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 44: Non-specific - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 1: Choroid plexus - Transmembrane transport
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,788
1
ENSG00000163347
CLDN1
Claudin 1
[ "O95832" ]
3
190305707-190322446
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002602", "HPA048319" ]
[ "ILVASC", "SEMP1" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Host-virus interaction" ]
[ "Host cell receptor for virus entry", "Receptor" ]
[ "Ichthyosis" ]
[]
[]
[]
[]
null
Enhanced
null
7
null
null
null
Cluster 36: Choroid plexus - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 58: Skin - Keratinization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Glioblastoma Multiforme", "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Pancreatic Adenocarcinoma" ]
10,789
2
ENSG00000163348
PYGO2
Pygopus family PHD finger 2
[ "Q9BRQ0" ]
1
154957026-154963853
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA023689", "HPA074813" ]
[]
[ "Predicted intracellular proteins" ]
[ "Wnt signaling pathway" ]
[]
[]
[ "Nucleoplasm" ]
[ "Plasma membrane" ]
[]
[]
Supported
Supported
null
13
No
No
Cluster 3: Non-specific - Nuclear processes
Cluster 6: Non-specific - Immune response
Cluster 45: Non-specific - Nuclear processes
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
10,790
2
ENSG00000163349
HIPK1
Homeodomain interacting protein kinase 1
[ "Q86Z02" ]
1
113929324-113977869
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA016664" ]
[ "KIAA0630", "MGC26642", "MGC33446", "MGC33548", "Myak", "Nbak2" ]
[ "Enzymes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Nucleoplasm", "Basal body", "Cytosol" ]
[ "Centrosome" ]
[]
[]
Supported
Approved
null
8
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 44: Non-specific - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 44: Bone marrow - Nuclear processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,791
6
ENSG00000163352
LENEP
Lens epithelial protein
[ "Q9Y5L5" ]
1
154993586-154994315
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "LEP503" ]
[ "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
1
null
null
null
Cluster 6: Non-specific - Immune response
Cluster 60: Prostate cancer - Unknown function
Cluster 11: Muller glia cells - Retinal homeostasis
null
Not detected
Not detected
null
Cancer enriched
Detected in single
4
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
10,792
9
ENSG00000163354
DCST2
DC-STAMP domain containing 2
[ "Q5T1A1" ]
1
155018520-155033781
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[ "FLJ32934" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
Cluster 7: Liver cancer - Metabolism
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 47: Testis - Mixed function
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in single
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,793
5