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Solitary plasmacytoma SP of the skull is an uncommon clinical entity that is characterized by alocalized proliferation of neoplastic monoclonal plasma cells This case report describes a50yearold male that presented with a headache and an exophytic soft mass on the occiputThe diagnosis of SP was based on the pathologic... | Thyroid_Cancer |
"development of cancer is a problem that has accompanied mankind for years The growing number of cases emerging drug resistance and the need to reduce the serious side effects of pharmacotherapy are forcing scientists to better understand the complex mechanisms responsible for the initiation promotion and progression o... | Thyroid_Cancer |
emergence of promising targeted therapies for the treatment of hepatocellular carcinoma HCCSorafenib has been the mainstay of treatment for a decade and newer modalities were ineffective and did not confer any increasedtherapeutic beneï¬t until the introduction of lenvatinib which was approved based on its noninferior... | Thyroid_Cancer |
Pathwayspecific model estimation for improved pathway annotation by network crosstalkMiguel CastresanaAguirre Erik L L SonnhammerPathway enrichment analysis is the most common approach for understanding which biological processes are affected by altered gene activities under specific conditions However it has been ... | Thyroid_Cancer |
Neurosteroids Biosynthesisand Physiological FunctionsShogo Haraguchi and Kazuyoshi Tsutsui Department of Biochemistry Showa University School of Medicine Tokyo Japan Graduate School of Integrated Sciencesfor Life Hiroshima University Hiroshima JapanSimilar to the adrenal glands gonads and placenta vertebrate brains ... | Thyroid_Cancer |
Is preoperative heart rate variability aprognostic indicator for overall survival andcancer recurrence in patients with primarycolorectal cancerM T A StrousID1 A M Daniels1 F M Zimmermann2 F N van Erning3 Y Gidron4 FJ Vogelaar1 Department of Surgery VieCuri Medical Centre Venlo The Netherlands Department of Cardiolog... | Thyroid_Cancer |
"rebound effect after stopping treatment with denosumab may be associated with rapid loss ofthe gains in bone mineral density achieved with treatment high levels of bone remodeling markers the occurrenceof vertebral fractures and even hypercalcemiaCase presentation A 64yearold osteoporotic Caucasian woman suffered from... | Thyroid_Cancer |
ShortTerm Consequences ofPediatric Anticancer TreatmentRegarding Blood Pressure MotorPerformance Physical Activity andReintegration Into Sports StructuresTina Keiser Dominik Gaser Christiane Peters Renate OberhofferFritz Sabine Kesting and Irene von Luettichau Edited byKirsten K NessSt Jude Childrens Research Ho... | Thyroid_Cancer |
lack of COVID19 diagnostic tests for the whole Spanish population thecurrent strategy is to identify the disease early to limit contagion in the communityAimTo determine clinical factors of a poor prognosis in patients with COVID19 infectionDesign and settingDescriptive observational retrospective study in three primar... | Thyroid_Cancer |
"Immune checkpoint inhibitors ICIs can induce immunerelated adverse events irAEs includingthyroid dysfunction There are only a few reports on Graves disease induced by ICIs We report a case of newonsetGraves disease after the initiation of nivolumab therapy in a patient receiving gastric cancer treatmentCase presenta... | Thyroid_Cancer |
generate a map of the copy number variations CNV segregating in a population of MurcianoGranadina goats the most important dairy breed in Spain and to ascertain the main biological functions of the genes that map to copy number variable regionsResults Using a dataset that comprised MurcianoGranadina goats genotype... | Thyroid_Cancer |
molecular heterogeneity of renal cell carcinoma RCC complicates the therapeutic interventions for advancedmetastatic disease and thus its management remains a significant challenge This study investigates the role of thelncRNA CDKN2BAS1 and miR1413p interactions in the progression and metastasis of kidney cancer Human ... | Thyroid_Cancer |
thyroid stimulating hormone highlightspleiotropic effects and inverse association withthyroid cancerWei Zhouet alThyroid stimulating hormone TSH is critical for normal development and metabolism Tobetter understand the genetic contribution to TSH levels we conduct a GWAS metaanalysisat million genetic markers in up to... | Thyroid_Cancer |
RNAs circRNAs are a novel and unique class of noncoding RNAs that are backspliced from premRNAs It hasbeen conï¬rmed that circRNAs are involved in various malignant behaviors of hepatocellular carcinoma HCCHowever the role of circRNA in the regulation of ferroptosis and the underlying mechanism remain unknown HerecIAR... | Thyroid_Cancer |
"Nonsmall cell lung cancer is the most common cause of cancer death worldwide highlighting the need fornovel therapeutic concepts In particular there is still a lack of treatment strategies for the group of elderly and frail patientswho are frequently not capable of receiving standard therapy regimens Despite comprisin... | Thyroid_Cancer |
"enzymatic cascade for posttranslational protein modiï¬cation It includes the ubiquitinactivatingenzyme E1 ubiquitinconjugating enzyme E2 and ubiquitin ligase E3 RINGtype E3 ubiquitin ligases catalyse theposttranslational proteolytic and nonproteolytic functions in various physiological and pathological processes such... | Thyroid_Cancer |
Circulating tumor cells CTCs derived from primary tumors andor metastatic tumors aremarkers for tumor prognosis and can also be used to monitor therapeutic efï¬cacy andtumor recurrence Circulating tumor cells enrichment and screening can be automatedbut the ï¬nal counting of CTCs currently requires manualintervention... | Thyroid_Cancer |
"Many cancerassociated single nucleotide polymorphisms SNPs are located in the genomic regionsof long noncoding RNAs lncRNAs Mechanisms of these SNPs in connection to cancer risk are not fullyunderstoodMethods Association of SNP rs140618127 in lncRNA LOC146880 with nonsmall cell lung cancer NSCLC wasevaluated in a case... | Thyroid_Cancer |
pathogenesis of multiple myeloma MM is not completely known Uncovering the potential mechanism of MM initiation and progression is essential for identifying novel diagnostic and therapeutic targets Herein we explored the function and the working mechanism of circular RNA circ_0007841 in MM progressionMethods Quantitat... | Thyroid_Cancer |
Genomics Score Based onGenomeWide Network Analysis forPrediction of Survival in GastricCancer A Novel PrognosticSignatureZepang Sun Hao Chen Zhen Han Weicai Huang Yanfeng Hu Mingli Zhao Tian LinJiang Yu Hao Liu Yuming Jiang and Guoxin LiDepartment of General Surgery Nanfang Hospital Southern Medical University Guang... | Thyroid_Cancer |
"pharmacological therapies and treatments targeting pancreatic neuroendocrine tumorsPNETs have proven ineffective far too often Therefore there is an urgent need for alternative therapeuticapproaches Zyflamend a combination of antiinflammatory herbal extracts that has proven to be effective invarious in vitro and in vi... | Thyroid_Cancer |
Adjunctive Therapy to Achieve Preoperative Euthyroidism in Graves Disease A Case Report Authors Contribution Study Design A Data Collection B Statistical Analysis C Data Interpretation D Manuscript Preparation E Literature Search F Funds Collection G ABDEF Noor Abdulghani AlghanimABDEF Shymaa M Alkah... | Thyroid_Cancer |
case of a 14year old boy with tumorassociated refractory epilepsy Positron emission tomography imaging demonstrated a region with heterogeneous high 11Cmethionine uptake and a region with homogenous low 18Ffluorodeoxyglucose uptake within the tumor Histopathological and genomic analyses confirmed the tumor as BRAF V600... | Thyroid_Cancer |
coronavirus disease COVID19 pandemic access to surgical care for patients with head and neck cancer HNC is limited and unpredictable Determining which patients should be prioritized is inherently subjective and difficult to assess The authors have proposed an algorithm to fairly and consistently triage patients and mi... | Thyroid_Cancer |
"Pressure sores are sometimes refractory to treatment often due to malnutrition Small intestinalbacterial overgrowth SIBO obstructs absorption in the digestive tract and causes malnutrition However little isknown about the association between pressure sore wound healing and SIBO Here we report a case of a patientwith a... | Thyroid_Cancer |
"Nonsmall cell lung cancer is the most common cause of cancer death worldwide highlighting the need fornovel therapeutic concepts In particular there is still a lack of treatment strategies for the group of elderly and frail patientswho are frequently not capable of receiving standard therapy regimens Despite comprisin... | Thyroid_Cancer |
performance demonstration of a hybrid compton camera with an active pinhole for wideband Xray and gammaray imagingAkihisa omata1 Jun Kataoka1 Kazuya fujieda1 Shogo Sato1 eri Kuriyama1 Hiroki Kato2 Atsushi toyoshima3 takahiro teramoto3 Kazuhiro ooe2 Yuwei Liu2 Keiko Matsunaga2 takashi Kamiya2 tadashi Watabe2 eku Shi... | Thyroid_Cancer |
Deacetylases inSkeletal Muscle Physiology andSystemic Energy HomeostasisImplications for Metabolic Diseasesand TherapyHaili Tian1 Sujuan Liu2 Jun Ren3 Jason Kai Wei Lee456 Ru Wang1 and Peijie Chen1 School of Kinesiology Shanghai University of Sport Shanghai China Department of Anatomy and Histology Schoolof Basic Me... | Thyroid_Cancer |
"rapeutic plasma exchange clears circulating soluble PD L1 and PD L1 positive extracellular vesicles Elizabeth Ann L Enninga2 Fabrice Lucien Matteoni3 Jacob J Orme Heather Dale4 Edwin Burgstaler4 Susan M Harrington3 Matthew K Ball4 Aaron S Mansfield1 Sean S Park5 Mathew S Block1 Svetomir N Markovic1 Yiyi Yan1 Haido... | Thyroid_Cancer |
poorest prognoses of all malignancies with little improvement in clinical outcome over the past years Pancreatic ductal adenocarcinoma is responsible for the vast majority of pancreatic cancer cases and is characterised by the presence of a dense stroma that impacts therapeutic efficacy and drives protumorigenic progr... | Thyroid_Cancer |
"elucidate the molecular mechanism underlying the involvement of abnormal DNA methylation in the development of glioma and identify potential newtargets for glioma therapyMethods The GSE79122 chip achieved from the Gene Expression Omnibus GEOdatabase containing glioma samples and normal samples was analyzed Methylati... | Thyroid_Cancer |
Detecting ulcerative colitis from a0colon a0samples a0using a0efficient a0feature selection and machine learningHanieh Marvi Khorasani1 a0Hamid a0Usefi2 Lourdes pe±acastillo1Ulcerative a0colitis a0UC a0is a0one a0of a0the a0most a0common a0forms a0of a0inflammatory a0bowel a0disease a0IBD a0characterized a0by a0infl... | Thyroid_Cancer |
"Previous evidence has suggested that lower gestational vitamin D levels might increase the risks ofadverse pregnancy and birth outcomes The results remain inconsistent and require further explorationMethods A total of Chinese motherinfant pairs were included in this retrospective cohort study Serumconcentrations of 2... | Thyroid_Cancer |
"MiRNAs play important roles in the development of ovarian cancer activation of primitive folliclesfollicular development oocyte maturation and ovulation In the present study we investigated the specific role ofmiR23a in cov434 cellsResults Downregulation of miR23a was observed in serum of PCOS patients compared with t... | Thyroid_Cancer |
"deltalike protein DLL3 may be related with prognosis inpatients with small cell lung cancer SCLC However this finding remains controversial in small cell lung cancerThis metaanalysis was systematically performed to evaluate the prognostic value of DLL3 in SCLCMethods The PubMed EMBASE and Web of Science databases wer... | Thyroid_Cancer |
This study aimed to investigate serum matrix metalloproteinase MMP2 and MMP9levels in patients with papillary thyroid carcinoma PTCMethods Fortyone patients with PTC undergoing ultrasoundguided radiofrequency ablationRFA and controls were included Serum MMP2 and MMP9 levels were determined byenzymelinked immunosorben... | Thyroid_Cancer |
EpidemiologyEPIDEMIOLOGICAL SCIENCERisk factors for hospital admissions related to COVID19 in patients with autoimmune inflammatory rheumatic diseasesDalifer D Freites Nu±ez1 Leticia Leon Arkaitz Mucientes1 Luis Rodriguez Rodriguez Judit Font Urgelles3 Alfredo Madrid Garca1 Jose I Colomer1 Juan A Jover34 B... | Thyroid_Cancer |
"conceptualization data curation investigation project administration supervision validation visualization writing review and editing Goneim I and Ibraheim A performed data curation Kamal NM was involved in literature review writingoriginal draft writing review and editing Alsofiani F and Alawur A performed literature ... | Thyroid_Cancer |
ORIGINAL Clinical Translational Immunology e1165 101002cti21165wwwwileyonlinelibrarycomjournalcti Elly Marcq1 Bianca von Scheidt2 Ashleigh S Davey2Novel combination immunotherapy for pancreatic cancerpotent antitumor effects with CD40 agonist andinterleukin15 treatmentJonas RM Van Audenaerde12Amanda J Oliver2 Jorrit... | Thyroid_Cancer |
" new coronavirus SARSCoV2 has determined a pneumonia outbreak in China Wuhan Hubei Province in December called COVID19 disease In addition to the personto person transmission dynamic of the novel respiratory virus it has been recently studied the role of environmental factors in accelerate SARSCoV2 spread and its let... | Thyroid_Cancer |
"Effects of lowdose computed tomography LDCT screening on lung cancercontains a that is not consistent with the data presented With reference to the National Lung ScreeningTrial NLST there are several flaws in the methodology overlooked Also there is no significant reduction in deathsfrom all causes following the scre... | Thyroid_Cancer |
"analyse the quality of information included in websites aimed at the public on COVID19Methods Yahoo Google and Bing search engines were browsed using selected keywords on COVID19ï¬rst websites from each search engine for each keyword were evaluated Validated tools wereThe used... | Thyroid_Cancer |
Coronavirus disease is caused by severe acute respiratory syndrome coronavirus SARSCoV2 and represents the causative agent of a potentially fatal disease The spread of the infection and the severe clinical disease have led to the widespread adoption of social distancing measures Special attention and efforts to prote... | Thyroid_Cancer |
Purpose Pancreatic ductal adenocarcinomas exhibit a high degree of desmoplasia due to extensive extracellular matrix deposition Encasement of mesenteric vessels by stroma in locally advanced pancreatic cancer LAPC prevents surgical resection This study sought to determine if the addition of a monoclonal antibody to co... | Thyroid_Cancer |
"Creative Commons Attribution Licensewhich permits unrestricted use distribution and reproduction in any medium provided the original work is properly citedAURKA a cell cycleregulated kinase is associated with malignant transformation and progression in many cancer types Weanalyzed the expression change of AURKA in pan... | Thyroid_Cancer |
Genetic alterations in the 3q263132 locus conferan aggressive prostate cancer phenotypeBenjamin S SimpsonSusan Heavey Jason Pitt5 Caroline M Moore6 Hayley C Whitaker Niedzica Camacho234 Hayley J Luxton Hayley Pye Ron Finn1Largescale genetic aberrations that underpin prostate cancer development and progressionsuch as... | Thyroid_Cancer |
Radial shock waves prevent growth retardation caused by the clinically used drug vismodegib in ex vivo cultured bonesSowmya Ramesh123 Lars Svendahl245 Vrisha Madhuri135 farasat Zaman2In childhood medulloblastoma patients the hedgehog antagonist vismodegib is an effective anticancer treatment but unfortunately induces... | Thyroid_Cancer |
Polyphenol induced improvements in glucose metabolism are associated with bile acid signaling to intestinal farnesoid X receptorKevin M Tveter1 Jose A Villa Rodriguez Alrick J Cabales1 Li Zhang2 Fiona G Bawagan1 Rocio M Duran1 Diana E Roopchand To cite Tveter a0KM Villa Rodriguez a0JA Cabales a0AJ et a0al Po... | Thyroid_Cancer |
" IBDFecal calprotectinEndoscopic activityIBD noninvasive managementThe term IBD is usually used for referring to a group of ammatory gastrointestinal diseases mainly Crohn'sdisease and ulcerative colitis Accordingly IBD arises as a result of inappropriate immune response to intestinalcommensal anisms among geneticall... | Thyroid_Cancer |
RANK are expressed in different cell types and tissues throughout thebody They were originally described for their essential roles in bone remodeling and theimmune system but have subsequently been shown to provide essential signals fromregulating mammary gland homeostasis during pregnancy to modulating tumorigenesisTh... | Thyroid_Cancer |
"Cellular recognition of microbial DNA is an evolutionarily conserved mechanism by which the innate immunesystem detects pathogens Cyclic GMPAMP synthase cGAS and its downstream effector stimulator of interferongenes STING are involved in mediating fundamental innate antimicrobial immunity by promoting the release ofty... | Thyroid_Cancer |
Construction of a novel prognosticpredicting modelcorrelated to ovarian cancerWeichun Tang12 Jie Li3 Xinxia Chang12 Lizhou Jia1 Qi Tang12 Ying Wang4 Yanli Zheng4 Lizhou Sun5 andZhenqing Feng121National Health Commission Key Laboratory of Antibody Technique Nanjing Medical University Nanjing Peoples Republic of China 2... | Thyroid_Cancer |
"Meningiomas are the most common primary central nervous system tumors Potential risk factorsinclude obesity height history of allergyatopy and autoimmune diseases but findings are conflicting This studysought to assess the role of the different risk factors in the development of meningioma in adolescentsyoungadultsMet... | Thyroid_Cancer |
"deltalike protein DLL3 may be related with prognosis inpatients with small cell lung cancer SCLC However this finding remains controversial in small cell lung cancerThis metaanalysis was systematically performed to evaluate the prognostic value of DLL3 in SCLCMethods The PubMed EMBASE and Web of Science databases wer... | Thyroid_Cancer |
"Ethnopharmacological relevance Tetrastigma hemsleyanum Diels et Gilg Themsleyanum a rare herbal plant distributed in subtropical areas of mainland China has become a focus of scientific attention in recent years because of its high traditional value including uses for treatment of children with fever pneumo... | Thyroid_Cancer |
Molecular Medicine The role of selenium metabolism andselenoproteins in cartilage homeostasisand arthropathiesDonghyun Kang Jeeyeon Lee Cuiyan Wu3 Xiong Guo3 Byeong Jae Lee24 JangSoo Chun5 andJinHong Kim AbstractAs an essential nutrient and trace element selenium is required for living anisms and its beneï¬cial role... | Thyroid_Cancer |
"unrestricted use distribution and reproduction in any medium provided the original work is properly citedPurpose The present study was aimed at determining the serum levels of actinin4 ACTN4 in cervical cancer CC andinvestigating the diagnostic and prognostic value of serum ACTN4 in CC Materials and Methods We include... | Thyroid_Cancer |
CD146 was originally identiï¬ed as a melanoma cell adhesion molecule MCAM and highly expressed in many tumors andendothelial cells However the evidence that CD146 acts as an adhesion molecule to mediate a homophilic adhesion through thedirect interactions between CD146 and itself is still lacking Recent evidence revea... | Thyroid_Cancer |
Electronic health records EHRs contain rich documentation regarding disease symptomsand progression but EHR data is challenging to use for diagnosis prediction due to its highdimensionality relative scarcity and substantial level of noise We investigated how to bestrepresent EHR data for predicting cervical cancer a se... | Thyroid_Cancer |
Neurosteroids Biosynthesisand Physiological FunctionsShogo Haraguchi and Kazuyoshi Tsutsui Department of Biochemistry Showa University School of Medicine Tokyo Japan Graduate School of Integrated Sciencesfor Life Hiroshima University Hiroshima JapanSimilar to the adrenal glands gonads and placenta vertebrate brains ... | Thyroid_Cancer |
patients who have diabetes suffer from Type DMT2DM Many studies suggest using the significant role of lncRNAs to improve thediagnosis of T2DM Machine learning and Data Mining techniques are tools that canimprove the analysis and interpretation or extraction of knowledge from the dataThese techniques may enhance the pr... | Thyroid_Cancer |
"evaluate the clinicopathologic characteristics of Lymph Node metastasisbetween investing layer of Cervical fascia and deep fascia of infrahyoid strap Muscles LNCM in papillary thyroidcarcinoma PTCMethods Retrospective review of patients with PTC who underwent thyroidectomy and central compartment neckdissection CND fr... | Thyroid_Cancer |
EndocrinesyPostoperative vocal fold dysfunction in covid19 era are we still intime for a recoveryElena Bonati Elena Giovanna Bignami2 Paolo Del Rio1Received May Accepted July Springer ScienceBusiness Media LLC part of Springer Nature To the EditorThe novel coronavirus COVID19 is a highly contagious zoonosis pro... | Thyroid_Cancer |
patients who have diabetes suffer from Type DMT2DM Many studies suggest using the significant role of lncRNAs to improve thediagnosis of T2DM Machine learning and Data Mining techniques are tools that canimprove the analysis and interpretation or extraction of knowledge from the dataThese techniques may enhance the pr... | Thyroid_Cancer |
construct a circRnAmiRnAmRnA regulatory network to explore potential pathogenesis and therapy options of clear cell renal cell carcinomaShuheng Bai1 YinYing Wu3 Yanli Yan1 Shuai Shao1 Jiangzhou Zhang2 Jiaxin Liu2 Beina Hui1 Rui Liu1 Hailin Ma1 Xiaozhi Zhang1 Juan Ren1clear cell renal cell carcinoma ccRcc is the most ... | Thyroid_Cancer |
Bone metastasis classification using wholebody images from prostate cancer patientsbased on convolutional neural networksapplicationNikolaos Papandrianos1 Elpiniki PapageiouID23 Athanasios Anagnostis34Konstantinos Papageiou4 General Department University of Thessaly Lamia Greece Faculty of Technology Dept of EnergySy... | Thyroid_Cancer |
" Despite several efforts the development of an effective vaccine for COVID19 may take a much longer timeTraditionalnatural medicine already experienced by humans could be an earlier solution Considering the researchteams experience in using nanoclays as highaffinity material for cancer metastasis melanoma treatment a... | Thyroid_Cancer |
THYROID development of thyroid hormone TH analogues was prompted by the attempt to exploit the effects of THon lipid metabolism avoiding cardiac thyrotoxicosis Analysis of the relative distribution of the a and bsubtypes of nuclear TH receptors TRa and TRb showed that TRa and TRb are responsible for cardiac andmetaboli... | Thyroid_Cancer |
Neuropilin1 regulated by miR320a participates in the progression of cholangiocarcinoma by serving as a coreceptorthat activates multiple signaling pathways The present study sought to investigate upstream lncRNAs that control theexpression of miR320aneuropilin1 axis and dissect some of the underlying mechanisms Here we... | Thyroid_Cancer |
test the hypothesis that levobupivacaine has antitumour effects on breast cancer cellsResults Colony formation and transwell assay were used to determine breast cancer cells proliferation Flow Cytometry annexin V and PI staining was used to investigate breast cancer cells apoptosis The effects of levobupivacaine on ... | Thyroid_Cancer |
molecular heterogeneity of renal cell carcinoma RCC complicates the therapeutic interventions for advancedmetastatic disease and thus its management remains a significant challenge This study investigates the role of thelncRNA CDKN2BAS1 and miR1413p interactions in the progression and metastasis of kidney cancer Human ... | Thyroid_Cancer |
"At present the relationship between hypothyroidism and the risk of breast cancer is still inconclusive Thismetaanalysis was used to systematically assess the relationship between hypothyroidism and breast cancer riskand to assess whether thyroid hormone replacement therapy can increase breast cancer riskMethods The re... | Thyroid_Cancer |
" IBDFecal calprotectinEndoscopic activityIBD noninvasive managementThe term IBD is usually used for referring to a group of ammatory gastrointestinal diseases mainly Crohn'sdisease and ulcerative colitis Accordingly IBD arises as a result of inappropriate immune response to intestinalcommensal anisms among geneticall... | Thyroid_Cancer |
"Oral cancer is one of the most common noncommunicable diseases worldwide This paper presentsan evaluation of the trends and geographical distributions of oral cancers in the Saudi Arabian populationMethods Data from Saudi Cancer Registry reports were used in this analysis which assessed the period between and All can... | Thyroid_Cancer |
Despite the proven benefits of iron chelation therapy ICT in the management of chronic iron overload and related complications compliance to longterm ICT is challenging Results from the ECLIPSE study an label randomized multicenter 2arm phase study evaluated the safety of deferasirox dispersible tablet and filmcoated... | Thyroid_Cancer |
EpidemiologyEPIDEMIOLOGICAL SCIENCERisk factors for hospital admissions related to COVID19 in patients with autoimmune inflammatory rheumatic diseasesDalifer D Freites Nu±ez1 Leticia Leon Arkaitz Mucientes1 Luis Rodriguez Rodriguez Judit Font Urgelles3 Alfredo Madrid Garca1 Jose I Colomer1 Juan A Jover34 B... | Thyroid_Cancer |
catalytic activity of human Telomerase Reverse Transcriptase TERT compensates for the loss of telomere length eroded during each cell cycle to ensure a correct division of stem and germinal cells In human tumors ectopic TERT reactivation most frequently due to hotspot mutations in the promoter region TERTp ie c1124 C ... | Thyroid_Cancer |
Computed Tomography Features andClinicopathological Characteristicsof Gastric Sarcomatoid CarcinomaYiyang Liu1 Pan Liang1 Kaixiang Feng2 Kuisheng Chen3 Songwei Yue1 Jiang Ji4Weiwei Li1 Xitong Zhao1 and Jianbo Gao1 Department of Radiology The First Afï¬liated Hospital of Zhengzhou University Zhengzhou China Department... | Thyroid_Cancer |
generate a map of the copy number variations CNV segregating in a population of MurcianoGranadina goats the most important dairy breed in Spain and to ascertain the main biological functions of the genes that map to copy number variable regionsResults Using a dataset that comprised MurcianoGranadina goats genotype... | Thyroid_Cancer |
CD146 was originally identiï¬ed as a melanoma cell adhesion molecule MCAM and highly expressed in many tumors andendothelial cells However the evidence that CD146 acts as an adhesion molecule to mediate a homophilic adhesion through thedirect interactions between CD146 and itself is still lacking Recent evidence revea... | Thyroid_Cancer |
Growing evidence has demonstrated that glutathione peroxidases GPXs family genes play critical roles in onset and progression of human cancer However a systematic study regarding expression diagnostic and prognostic values and function of GPXs family genes in breast cancer remains absentMaterials and methods Several d... | Thyroid_Cancer |
Radial shock waves prevent growth retardation caused by the clinically used drug vismodegib in ex vivo cultured bonesSowmya Ramesh123 Lars Svendahl245 Vrisha Madhuri135 farasat Zaman2In childhood medulloblastoma patients the hedgehog antagonist vismodegib is an effective anticancer treatment but unfortunately induces... | Thyroid_Cancer |
pathogenesis of multiple myeloma MM is not completely known Uncovering the potential mechanism of MM initiation and progression is essential for identifying novel diagnostic and therapeutic targets Herein we explored the function and the working mechanism of circular RNA circ_0007841 in MM progressionMethods Quantitat... | Thyroid_Cancer |
Health related quality of life functional impairment and comorbidity in people with mild to moderate chronic kidney disease a cross sectional studySimon DS Fraser Jenny Barker1 Paul J Roderick1 Ho Ming Yuen1 Adam Shardlow2 James E Morris1 Natasha J McIntyre2 Richard J Fluck2 Chris W McIntyre3 Maarten W Taal ... | Thyroid_Cancer |
" COVID19 pathways for brain andheart injury in comorbidity patients A role of medical imaging and artificial intelligencebased COVIDseverity classification A review Computers in Biology and Medicine 101016jcompbiomed2020103960 0cThis is a PDF file of an that has undergone enhancements after acceptance such as the a... | Thyroid_Cancer |
IFNBased Biotherapeutics toHarness the Host AgainstFootAndMouth DiseaseGisselle N Medina Teresa de los Santos and Fayna DiazSan Segundo Plum Island Animal Disease Center PIADC ARS USDA Orient Point NY United States Kansas State University Collegeof Veterinary Medicine Manhattan KS United StatesFootandmouth disease ... | Thyroid_Cancer |
" The advent of new cancer therapies alongside expected growth and ageing of the population better survival rates and associated costs of care is uncovering aneed to more clearly deï¬ne and integrate supportive care services across the whole spectrum of the disease The current focus of cancer care is on initialdiagnos... | Thyroid_Cancer |
Adjunctive Therapy to Achieve Preoperative Euthyroidism in Graves Disease A Case Report Authors Contribution Study Design A Data Collection B Statistical Analysis C Data Interpretation D Manuscript Preparation E Literature Search F Funds Collection G ABDEF Noor Abdulghani AlghanimABDEF Shymaa M Alkah... | Thyroid_Cancer |
"Pancreatic cancer PC is one of the most aggressive cancers and has an extremely poor prognosisworldwide Long noncoding RNA lncRNA has been reported to be a potential prognostic biomarker in theinitiation and prognosis of PC Nevertheless the biological functions and the detailed molecular mechanism ofLINC00514 in PC re... | Thyroid_Cancer |
Activation by NaturalPhytochemicals An OverviewConcetta Iside Marika Scafuro Angela Nebbioso and Lucia Altucci Department of Precision Medicine University of Campania Luigi Vanvitelli Naples ItalySirtuins are class III histone deacetylases whose enzymatic activity is dependent on NADas a cofactor Sirtuins are repor... | Thyroid_Cancer |
Drug repurposing identifying novel indications for drugs bypasses common drug development pitfalls to ultimately deliver therapies to patients faster However most repurposingdiscoveries have been led by anecdotal observations eg Viagra or experimentalbasedrepurposing screens which are costly timeconsuming and imprecise... | Thyroid_Cancer |
Hepatitis B virus HBV infection has been associated with the risk andprognosis of many malignancies Nevertheless the association between HBV and theprognosis of breast cancer is unclear The objectives of this study were to investigate theprognostic role of hepatitis B surface antigen HBsAg and to integrate HBsAg to est... | Thyroid_Cancer |
Association of variant on the promoter of cluster ofdifferentiation in graves disease and gravesophthalmopathyYuHuei Liu123 ChiouYuan Shen1 and FuuJen Tsai3451Graduate Institute of Integrated Medicine China Medical University Taichung Taiwan 2Drug development center China Medical University Taichung Taiwan 3Department... | Thyroid_Cancer |
The effects of tissue fixation on sequencingand transcript abundance of nucleic acidsfrom microdissected liver samples ofsmallmouth bass Micropterus dolomieuHeather L WalshID Adam J Sperry Vicki S BlazerUS Geological Survey National Fish Health Research Laboratory Leetown Science Center KearneysvilleWest Virginia Unit... | Thyroid_Cancer |
coronary arterybypass grafting thrombosis ï¬brin ï¬brinogen mutationIntroduction Intraoperative thrombosis of saphenous veins SV during harvesting is very rareCase Report We present a case of a 60yearold male patient with multivesselcoronary artery disease and a history of a nonST elevation acute coronary syndromea... | Thyroid_Cancer |
"Mareks disease MD is a chicken neoplastic disease which brings huge economic losses to theglobal poultry industry The wild type p53 a tumor suppressor gene plays a key role in blocking cell cyclepromoting apoptosis and maintaining the stability of the genome However the mutant p53 losses its tumorinhibitory role and ... | Thyroid_Cancer |
genes of papillary thyroidcarcinoma by integrated bioinformatics analysisGang Xue11Department of Otorhinolaryngology Head and Neck Surgery The First Afï¬liated Hospital of Hebei North University Zhangjiakou China 2Department of Histology andEmbryology Hebei North University Zhangjiakou ChinaJingFang Wu2 Da Pei1 Dong... | Thyroid_Cancer |
American Joint Committee on Cancer AJCC Cancer Staging Manual 8th edition we explored the characteristics of central lymph node metastasis CLNM of papillary thyroid microcarcinoma PTMC in elderly patients ¥ years of age Our goal was to provide references for establishing a lymph node dissection scheme i... | Thyroid_Cancer |
"Severe COVID19 has a high mortality rate Comprehensive pathological descriptions of COVID19 are scarce and limited in scope We aimed to describe the histopathological findings and viral tropism in patients who died of severe COVID19Methods In this case series patients were considered eligible if they were ... | Thyroid_Cancer |
CASE REPORTpublished August 103389fbioe202000929SecondGeneration RTQuIC Assayfor the Diagnosis ofCreutzfeldtJakob Disease Patientsin BrazilBreno Jos Alencar Pires Barbosa1 Bruno Batitucci Castrillo1 Ricardo Pires Alvim1Marcelo Houat de Brito1 Helio R Gomes1 S´nia M D Brucki1 Jerusa Smid1Ricardo Nitrini1 Michele C Lan... | Thyroid_Cancer |
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