OpenThyroidDB
A multicenter, multitask thyroid ultrasound data resource supporting the ThyroidXAgent evidence workflow.
OpenThyroidDB integrates curated public thyroid ultrasound resources and institutionally governed clinical cohorts into a full-spectrum resource for segmentation, benign–malignant classification, report generation, and malignant-lesion stratification across diverse scanners and acquisition settings.
This Hugging Face repository (MedXAgent/OpenThyroidDB) is the data-distribution layer of OpenThyroidDB. It separates redistributed or processed external resources from MedXAgent-governed cohorts, while preserving dataset-level provenance and archive boundaries.
Scope of the resource
The task organization follows Figure 1 of the ThyroidXAgent study:
| Task | Evidence represented in the current repository | Primary use |
|---|---|---|
| Segmentation | CineClip, TGVideo, ThyroidXL, TN3K, PKTN, DDTI, TN5000 masks, TNVideo | Pixel-/region-level delineation of thyroid structures and lesions |
| Classification | AHU, ThyroidXL, ThyUS2Path, TN5000/TN5K, TN3K, DDTI, TNVideo | Thyroid nodule diagnosis and categorization |
| Report generation | KMVE, SMU-HMC, ZJH-TS, TNVideo | Standardized report generation from ultrasound images or videos |
| Malignant-lesion stratification | Supporting thyroid image resources and task-specific ThyroidXAgent cohorts | FTC/PTC prediction and lymph-node-metastasis subtype classification |
Figure 1 reports task-specific curated subsets rather than raw archive totals. Examples include:
- Public segmentation resources: CineClip (17,417), TGVideo (15,186), ThyroidXL (11,631), TN3K (5,347), PKTN (1,003), and DDTI (637 images).
- Public classification resources: AHU (125,896), ThyroidXL (11,631), ThyUS2Path (8,508), TN5K (5,000), TN3K (5,347), and DDTI (349 images).
- Report-generation resources: KMVE (2,474 reports / 15,921 images), SMU-HMC (23,955 reports / 248,194 images), ZJH-TS (353 reports / 4,471 images), and a TNVideo report-generation subset (145 case videos).
- TNVideo task subsets: 148 cases for segmentation/classification and 145 case videos for report generation in the paper workflow.
Scanner and acquisition diversity
OpenThyroidDB spans still images, cine clips, videos, masks, bounding boxes, categorical labels, and free-text reports collected across heterogeneous acquisition environments. Scanner families represented in the study include, among others:
- GE LOGIQ E9 and GE S7
- Fujifilm ARIETTA 850 and Hitachi Aloka ARIETTA V70
- Mindray RESONA 70B
- Toshiba Nemio 30 / Nemio MX
- Esaote MyLab
- Samsung Medison RS80
- SuperSonic Imagine Aixplorer Ultimate
Scanner availability and metadata completeness vary by source dataset.
Current repository structure
The layout below reflects the current Hugging Face release:
OpenThyroidDB/
├── ExternalDatasets/
│ ├── AHU/
│ │ └── AHU-ProcessedData.zip
│ ├── CineClip/
│ │ └── Cine-clip.zip
│ ├── DDTI/
│ │ ├── DDTI_SourceData.zip
│ │ └── DDTI_processed.zip
│ ├── KMVE/
│ │ └── KMVE.zip
│ ├── PKTN/
│ │ └── PKTN.zip
│ ├── TG3K/
│ │ └── tg3k.zip
│ ├── TGVideo/
│ │ └── TGVideo.zip
│ ├── TN3K/
│ │ └── TN3K.zip
│ ├── TN5000/
│ │ ├── TN5000.zip
│ │ └── TN5K_MASK_SAM2_L.zip
│ ├── ThyUS2Path/
│ │ └── ThyUS2Path.zip
│ ├── ThyroidXL/
│ │ └── ThyroidXL.zip
│ └── ZJH-2K/
│ └── ZJH-2K.zip
└── MedXAgentDatasets/
├── SMU-HMC/
│ ├── Batch1.zip ... Batch15.zip
│ ├── Batch_Multiple_Cases.zip
│ └── test_set_single.json
├── TNVideo/
│ ├── SourceVideoAndAnno.zip
│ ├── VIDEO_DATASET.zip
│ └── VIDEO_ImageAndMask.zip
└── ZJH-TS/
├── ZJH-TS.zip
└── test_150cases_manifest.csv
Released components
ExternalDatasets
ExternalDatasets/ contains source-aligned or processed archives derived from publicly described datasets. Each subdirectory is kept separate to make provenance, licensing, and citation easier to audit.
| Directory | Current archive(s) | Main task relevance |
|---|---|---|
AHU/ |
AHU-ProcessedData.zip |
Classification |
CineClip/ |
Cine-clip.zip |
Segmentation, classification |
DDTI/ |
DDTI_SourceData.zip, DDTI_processed.zip |
Segmentation, classification |
KMVE/ |
KMVE.zip |
Report generation |
PKTN/ |
PKTN.zip |
Segmentation |
TG3K/ |
tg3k.zip |
Thyroid ultrasound image analysis |
TGVideo/ |
TGVideo.zip |
Video/frame segmentation |
TN3K/ |
TN3K.zip |
Segmentation, classification |
TN5000/ |
TN5000.zip, TN5K_MASK_SAM2_L.zip |
Detection/classification and derived SAM2 masks |
ThyUS2Path/ |
ThyUS2Path.zip |
Classification |
ThyroidXL/ |
ThyroidXL.zip |
Segmentation, classification, detection |
ZJH-2K/ |
ZJH-2K.zip |
Thyroid ultrasound image analysis |
Users must consult and cite the original publication and license for every external dataset they use. Inclusion in this repository does not relicense an external resource.
MedXAgentDatasets
MedXAgentDatasets/ contains institutionally governed or MedXAgent-curated releases used by the ThyroidXAgent workflow.
SMU-HMC
- Multicenter image–report cohort for thyroid ultrasound report generation.
- The paper cohort contains 23,955 reports and 248,194 images.
- The current release is distributed as 15 batch archives, an additional multiple-case archive, and
test_set_single.json.
ZJH-TS
- De-identified thyroid ultrasound image–report cohort.
- Full archive: 353 reports and 4,471 images.
test_150cases_manifest.csvprovides the final selected evaluation subset of 150 reports and 2,034 images.- Manifest columns are
index,report_id,data_dir,n_images,findings,impression, andtime.
TNVideo
- Thyroid ultrasound video resource supporting segmentation, classification, and video-conditioned report generation.
SourceVideoAndAnno.zip: source videos and sparse frame-level annotations.VIDEO_ImageAndMask.zip: extracted images and masks.VIDEO_DATASET.zip: processed video-oriented release.- Frame annotations in the source archive are sparse Pascal VOC bounding boxes rather than dense per-frame segmentation masks.
Access, governance, and responsible use
By requesting or using this repository, users agree to:
- Use the data only for legitimate research, education, and method development permitted by the applicable source terms.
- Respect the original licenses, citations, and redistribution restrictions of all external datasets.
- Follow the approved access conditions for institutionally governed cohorts.
- Not attempt to identify or contact any individual represented in the data.
- Not use the repository as a substitute for clinical judgment or as a clinically validated diagnostic product.
- Apply appropriate security, ethics, and institutional review procedures when handling downloaded data.
Download
Authenticate and request access on the dataset page before downloading gated files:
hf auth login
Download a specific component:
hf download MedXAgent/OpenThyroidDB \
"MedXAgentDatasets/ZJH-TS/ZJH-TS.zip" \
--repo-type dataset
Download a directory with Python:
from huggingface_hub import snapshot_download
snapshot_download(
repo_id="MedXAgent/OpenThyroidDB",
repo_type="dataset",
allow_patterns=["MedXAgentDatasets/ZJH-TS/*"],
local_dir="OpenThyroidDB",
)
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