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Preventing postoperative acute bleeding of the upper part of the gastrointestinal tract. Two hundred and ninety-eight critically ill patients at risk for the development of postoperative stress ulcers and bleeding were randomized into three groups. The first group comprised 85 patients who received meciadanol, a new bi... | digestive system diseases |
Neurologic complications in chronic renal failure: a retrospective study. We have retrospectively examined 324 patients with chronic renal failure and evaluated the probable underlying causes of neurologic complications, laboratory data and therapeutic interventions. The common neurologic problems in our patients were ... | cardiovascular diseases |
Septic Streptococcus milleri spondylodiscitis. We describe 2 patients presenting lumbar spondylitis due to Streptococcus milleri. In both cases origin was related to preexistent intestinal pathology. Surgical drainage of a collection of pus was necessary in one case. Longterm antibiotic therapy led to full recovery. De... | digestive system diseases |
Gallbladder surgery following cholecystlithotripsy: suggested guidelines for treatment Twenty-three of 229 symptomatic patients undergoing cholecystlithotripsy underwent surgical intervention: 22 of the patients had cholecystectomy performed (five also undergoing choledochotomy) and one patient had a cholecystostomy. O... | general pathological conditions |
Stress and sodium intake in neural control of renal function in hypertension. The interaction between genetic and environmental factors is important in the pathophysiology of hypertension. By examining the effects of two environmental factors--acute psychoemotional stress and dietary sodium intake--in rats with genetic... | cardiovascular diseases |
Proliferation markers Ki-67 and p105 in soft-tissue lesions. Correlation with DNA flow cytometric characteristics. Frozen tissue immunoreactivity with Ki-67, a monoclonal antibody that recognizes a nuclear antigen in nonresting or proliferating cells, was compared to DNA flow cytometry results (from fresh tissue) in a ... | neoplasms |
Clinical-computed tomographic correlations of lacunar infarction in the Stroke Data Bank. Lacunar stroke was diagnosed in 337 (26%) of the 1,273 patients with cerebral infarction among the 1,805 total in the Stroke Data Bank. We analyzed the 316 patients with classic lacunar syndromes. Among these, 181 (57%) had pure m... | nervous system diseases |
Thromboxane receptor blockade prevents pulmonary hypertension induced by heparin-protamine reactions in awake sheep We used competitive thromboxane A2-prostaglandin endoperoxide receptor blockade (SQ 30,741) as a probe to evaluate the role of thromboxane in ovine pulmonary vasoconstriction associated with protamine rev... | cardiovascular diseases |
Coeliac disease and malignancy of the duodenum: diagnosis by endoscopy, successful treatment of the malignancy, and response to a gluten free diet. A patient presented with subtotal villous atrophy and a malignant duodenal tumour of uncertain histogenesis. He was successfully treated by resection and chemotherapy and t... | digestive system diseases |
Combination therapy for anaplastic giant cell thyroid carcinoma. Since 1981, 20 patients with anaplastic giant cell carcinoma of the thyroid have been prospectively treated according to a combination regimen of chemotherapy and external beam radiation therapy. Two types of chemotherapy were used every 4 weeks, dependin... | neoplasms |
Stridor: intracranial pathology causing postextubation vocal cord paralysis. During an 18-month period in a pediatric intensive care unit, nine patients with vocal cord paralysis were identified using flexible bronchoscopy. When tracheally extubated, each child was found to have stridor. The children ranged in age from... | cardiovascular diseases |
Changes in interferon receptors on peripheral blood mononuclear cells from patients with chronic hepatitis B being treated with interferon. We studied the binding of 125I-labeled human interferon-alpha to peripheral blood mononuclear cells and the activity of 2',5'-oligoadenylate synthetase in peripheral blood mononucl... | digestive system diseases |
Hyperhomocysteinemia: an independent risk factor for vascular disease. BACKGROUND. Hyperhomocysteinemia arising from impaired methionine metabolism, probably usually due to a deficiency of cystathionine beta-synthase, is associated with premature cerebral, peripheral, and possibly coronary vascular disease. Both the st... | cardiovascular diseases |
Systemic pattern of free radical generation during coronary bypass surgery. Diffuse impairment of ventricular function after cardiac surgery may be related to the generation during reperfusion of the myocardium of free radicals derived from oxygen. Fifteen patients undergoing elective coronary bypass surgery were studi... | general pathological conditions |
Atrial fibrillation and left atrial enlargement: cause or effect? In a blinded controlled study, 58 consecutive patients with definite left atrial enlargement (M-mode dimension of at least 45 mm) were followed up after 1-2 years. The aim of the study was to examine the following: (a) the prospective risk of developing ... | cardiovascular diseases |
Anxiety and depression in patients with chronic urticaria and generalized pruritus. Thirty-four dermatology out-patients with chronic idiopathic urticaria and 34 with idiopathic generalized pruritus were investigated using standardized self-assessment psychological questionnaires to determine the incidence of significa... | general pathological conditions |
Different tumor-derived p53 mutants exhibit distinct biological activities. In its wild-type form, the protein p53 can interfere with neoplastic processes. Tumor-derived cells often express mutant p53. Full-length mutant forms of p53 isolated so far from transformed mouse cells exhibit three common properties in vitro:... | general pathological conditions |
What is the best predictor of spontaneous ventricular tachycardia and sudden death after myocardial infarction? BACKGROUND. Death during the first year after myocardial infarction is most commonly due to spontaneous ventricular tachycardia (VT) or fibrillation (VF). The purpose of this study was to compare, in a single... | general pathological conditions |
Normal angiograms and carotid pathology. Nonstenotic ulcerated atherosclerotic plaques of the carotid arteries may be associated with symptoms of transient ischemic attacks, amaurosis fugax, and stroke. Preoperative evaluation of patients with these symptoms has traditionally included ultrasound and arch aortography an... | cardiovascular diseases |
The effect of cesarean delivery on birth outcome in very low birth weight infants. National Institute of Child Health and Human Development Neonatal Research Network. To determine whether cesarean delivery is associated with a better outcome than vaginal delivery for infants weighing less than 1500 g (very low birth we... | general pathological conditions |
Surveillance of in situ infrainguinal bypass grafts: conventional vs. color flow duplex ultrasonography. Surveillance of in situ saphenous vein bypass grafts with duplex scanning detects graft abnormalities which may lead to graft thrombosis. Correction of these defects, while grafts are still patent, potentially impro... | general pathological conditions |
Outpatient laparoscopic laser cholecystectomy. Laparoscopic laser cholecystectomy has been performed clinically in the United States since 1988. After refinement of the technique, the procedure was offered on an outpatient basis. Eighty-three patients underwent laparoscopic laser cholecystectomy during the study period... | digestive system diseases |
The effect of large uterine fibroids on urinary bladder function and symptoms. Fourteen patients with large uterine fibroids and urinary symptoms were treated with monthly injections of [D-Trp6]-luteinizing hormone-releasing hormone microcapsules. The average uterine size before treatment was 728 ml; it dropped to 323 ... | neoplasms |
Surgical aspects of malaria. The spread of drug-resistant organisms and increased international travel makes malaria a disorder of ever-increasing importance. This report reviews those aspects of malaria of surgical relevance. The importance of the spleen in host defence against malaria and other infections makes splen... | general pathological conditions |
Extracorporeal cholecystolithotripsy without oral chemolitholysis. One hundred thirty-six patients completed extracorporeal biliary lithotripsy (EBL) for symptomatic cholecystolithiasis. Sonographic evidence of complete clearance of all stone fragments was the only criterion for treatment success, which occurred in 32 ... | digestive system diseases |
Skewflap versus long posterior flap in below-knee amputations: multicenter trial. A multicenter trial of alternative techniques for below-knee amputation is described in which surgeons in 11 centers randomized 191 patients with end-stage occlusive vascular disease to two different methods of stump construction. The ske... | cardiovascular diseases |
Prognostic determinants in extracorporeal membrane oxygenation for respiratory failure in newborns. Extracorporeal membrane oxygenation (ECMO) is becoming an accepted therapeutic modality for newborn respiratory failure, but there is little information available regarding the prognostic determinants with this technique... | cardiovascular diseases |
Renal function in obstructive jaundice in man: cholangiocarcinoma model. Renal function with respect to water clearance and renal hemodynamics was studied in 15 patients with obstructive jaundice due to cholangiocarcinoma. The results were compared with those of the control normal subjects. There was no change in renal... | neoplasms |
Causes and consequences of blood pressure alterations in obstructive sleep apnea. The obstructive sleep apnea (OSA) syndrome has been considered to be a cause of both transient blood pressure elevations during sleep and sustained hypertension during the awake state. The purpose of this review was to examine critically ... | nervous system diseases |
Effect of hyperkalemia on experimental myocardial depression by verapamil. Three patients with systemic hypotension and sinus bradycardia that were initially refractory to conventional therapy responded well to intravenous calcium administration. Two-dimensional echocardiography revealed immediate reversal of severe le... | general pathological conditions |
One hundred percent oxygen reverses muscle hypoxia in a rat hindlimb model of acute arterial occlusion. Significant morbidity results from extremity ischemia after acute arterial occlusion. Reestablishment of arterial flow is considered to be the ideal treatment, yet substantial tissue loss can occur before this is acc... | cardiovascular diseases |
Platelet monoamine oxidase activity in female migraine patients. Platelet monoamine oxidase activity (MAO) in a group (n = 17) of white, female migraineurs during an acute migraine attack was similar to both the values obtained for the same group of patients two to three weeks after the headache episode (pain-free peri... | nervous system diseases |
Isolated calf venous thrombosis: diagnosis with compression US. Compression ultrasound (US) is an excellent means of evaluating the femoral and popliteal veins but is generally regarded as inadequate for the diagnosis of calf vein thrombosis. This prospective study evaluated compression sonography of the calf veins in ... | general pathological conditions |
Localization of malignant melanoma using monoclonal antibodies. Finding a screening test to evaluate patients with cancer for occult metastatic disease, as well as imaging all known disease, is a goal of research efforts. Twenty-nine evaluable patients with deeply invasive (stage I), regional nodal (stage II), or syste... | general pathological conditions |
A huge intracranial xanthogranuloma in the middle cranial fossa: case report. Xanthogranulomas of the dura presenting with clinical symptoms are rare. We report here a case of a huge dural xanthogranuloma in the middle cranial fossa, which caused hemiparesis through marked displacement and stenosis of the middle cerebr... | general pathological conditions |
Spontaneous rupture of liver during pregnancy: current therapy. Spontaneous hepatic rupture secondary to severe pregnancy-induced hypertension is associated with a high rate of maternal and fetal mortality. Numerous types of surgical management have been described, but a uniform surgical approach has not been accepted.... | digestive system diseases |
Further notes on Munchausen's syndrome: a case report of a change from acute abdominal to neurological type. A rare case of Munchausen's syndrome beginning in early childhood is described. The diagnosis of Munchausen's syndrome was made at the age of 29 years, after the symptoms had changed from acute abdominal to neur... | digestive system diseases |
New quantitative method for evaluating tricuspid regurgitation. A new quantitative method for evaluating regurgitation (TR) is proposed in order to select the most suitable treatment for functional TR associated with acquired valvular heart disease. The regurgitant volume per beat (VTR) is calculated using two-dimensio... | cardiovascular diseases |
Presentation of breast carcinoma as Volkmann's contracture due to skeletal muscle metastases. Metastases to the skeletal muscles are extremely rare. They usually occur during the course of a pulmonary or digestive carcinoma. We describe a case of breast carcinoma presenting with forearm muscle metastases and Volkmann's... | cardiovascular diseases |
Recovery time of independent function post-stroke. Stroke patients undergoing physical rehabilitation were monitored daily to determine the length of time needed to recover independent function. Of the 93 patients admitted, there were 45 who could not attain the sitting position independently, 75 who could not walk ind... | nervous system diseases |
Growth hormone inhibits tumor metastasis. The effect of growth hormone on tumor growth and metabolism in the tumor-bearing host is unknown. This study was done to determine the effect of recombinant growth hormone on primary tumor growth, tumor metastasis, and carcass weight in tumor-bearing animals. Twenty-seven femal... | neoplasms |
Conjunctival involvement in pemphigus vulgaris: a clinical, histopathological and immunofluorescence study. Eleven patients with pemphigus vulgaris and with eye complaints had histopathological and direct immunofluorescence (DIF) studies on biopsies of their conjunctivae. In eight of the patients the ocular symptoms pr... | cardiovascular diseases |
One hundred percent incidence of hemidiaphragmatic paresis associated with interscalene brachial plexus anesthesia as diagnosed by ultrasonography. Interscalene brachial plexus anesthesia for shoulder surgery routinely includes sensory anesthesia of the fourth and fifth cervical nerves. The authors reasoned that some d... | general pathological conditions |
HMPAO-SPECT imaging resembling Alzheimer-type dementia in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS). Single-photon emission computed tomography (SPECT) of the brain using hexamethyl propylene amine oxime (HMPAO) was performed in a 37-year-old patient suffering from mitochondr... | nervous system diseases |
A perspective on reducing salt intake. Epidemiological, clinical, and experimental evidence links excessive salt consumption to hypertension; there appears to be no evidence that it is beneficial. I conclude that it should be public policy to advise and help Americans to reduce their salt intake. Because even mild hype... | cardiovascular diseases |
Cardiomyopathy associated with the smoking of crystal methamphetamine. The smoking of crystal methamphetamine, or "ice," is a growing drug abuse problem in the United States. The toxic effects of methamphetamine smoking have not been well described. We describe two patients with cardiovascular toxic effects associated ... | cardiovascular diseases |
Aggressive blood conservation in coronary artery surgery: impact on patient care. Data on 100 consecutive non-emergency coronary artery bypass (CABG) patients were analyzed retrospectively. Sixty-nine patients received no homologous blood (Group I). Thirty-one patients received a total of 118 units of blood products av... | general pathological conditions |
Fine surface structure of an intraspinal neurenteric cyst: a scanning and transmission electron microscopy study. The case of an 11-year-old boy with an intraspinal neurenteric cyst, which recurred 8 years and 3 months after surgery, is presented. Scanning and transmission electron microscopy of the cyst epithelium rev... | nervous system diseases |
Anatomical, physiological, and theoretical basis for the antiepileptic effect of vagus nerve stimulation. The vagus is a mixed nerve carrying somatic and visceral afferents and efferents. The majority of vagal nerve fibers are visceral afferents and have a wide distribution throughout the central nervous system (CNS) e... | nervous system diseases |
Neuroleptic malignant syndrome. When levodopa withdrawal is the cause. Neuroleptic malignant syndrome has been described in patients receiving dopamine antagonists and in a few patients after withdrawal of dopaminergic antiparkinson therapy. Complications affect almost all organ systems and can be life-threatening. Mos... | nervous system diseases |
Fistulas between the aorta and tracheobronchial tree. Aortobronchial fistula is a rare condition that is invariably fatal if not diagnosed and surgically treated. With appropriate surgical intervention, survival rates greater than 70% can be achieved. A review of the literature and an illustrative case report are prese... | general pathological conditions |
Final report of the French multicenter phase II study of the nitrosourea fotemustine in 153 evaluable patients with disseminated malignant melanoma including patients with cerebral metastases. One hundred sixty-nine patients with histologic evidence of disseminated malignant melanoma, including patients with cerebral m... | neoplasms |
Disability from bicycle-related injuries in children. Bicycle crashes are a major cause of injuries in childhood. The goal of this study was to determine the long-term disabilities caused by bicycle-related injuries, and to clarify the long-term treatment priorities of injured children. Hospital records of 372 children... | general pathological conditions |
Management of aortic insufficiency in chronic aortic dissection. From January 1980 to December 1988, 44 patients with chronic aortic dissection and aortic insufficiency underwent operation. This group of patients was analyzed to evaluate the outcome of those in whom the aortic valve was preserved compared with those ha... | general pathological conditions |
Timing and mechanism of in-hospital and late death after primary coronary angioplasty during acute myocardial infarction. The effect of early myocardial reperfusion on patterns of death after acute myocardial infarction (AMI) is unknown. Thus, the mechanism and timing of in-hospital and late deaths among a group of 614... | cardiovascular diseases |
CD11c (LEU-M5) expression characterizes a B-cell chronic lymphoproliferative disorder with features of both chronic lymphocytic leukemia and hairy cell leukemia. Chronic lymphocytic leukemia (CLL) and hairy cell leukemia (HCL) are two common chronic lymphoproliferative disorders, each having characteristic clinical, mo... | general pathological conditions |
Results and complications of angioplasty in fibromuscular disease. Percutaneous transluminal angioplasty (PTA) was used to treat 66 patients with 85 renal artery stenoses due to fibromuscular dysplasia. The hypertension was refractory to medical management in 46 patients, and the initial success rate was 100%. Clinical... | cardiovascular diseases |
'Locked-in syndrome' for 27 years following a viral illness: clinical and pathologic findings. We describe a man who, after a presumed encephalitic illness, was "locked-in" for 27 years. His CT and autopsy findings showed atrophy of the brainstem and a cystic lesion at the base of the pons. He survived longer than most... | neoplasms |
Mean arterial blood pressure changes in premature infants and those at risk for intraventricular hemorrhage. Bedside microcomputer-derived, minute-to-minute mean arterial pressure (MAP) values during the first 48 hours of life were studied in 100 preterm babies with birth weight less than or equal to 1500 gm. In those ... | general pathological conditions |
Imaging of patients with stage D prostatic carcinoma. In conclusion, it would appear from present evidence that several statements can be made. First, MRI is the most accurate method of staging the periprostatic spread of carcinoma. Both the prostate and the regional nodes can be evaluated. The role of ultrasound is, a... | neoplasms |
Loss of photosynthetic and chlororespiratory genes from the plastid genome of a parasitic flowering plant. Photosynthesis is the hallmark of plant life and is the only plastid metabolic process known to be controlled by plastid genes. The complete loss of photosynthetic ability, however, has occurred on several indepen... | general pathological conditions |
Hepatic infarction in preeclampsia. Two cases of hepatic infarction in toxemia of pregnancy are described. Both patients had associated laboratory findings of the HELLP syndrome (hemolytic anemia, elevated liver enzyme levels, and low platelet levels). Computed tomography (CT) showed nonenhancing low-attenuation areas ... | general pathological conditions |
Human coronary transplantation-associated arteriosclerosis. Evidence for a chronic immune reaction to activated graft endothelial cells. Occlusive disease of coronary arteries of engrafted hearts is the major obstacle to long-term survival of human cardiac allografts. The pathogenesis of this process remains uncertain.... | cardiovascular diseases |
Effect of amiodarone on erythrocyte shape and membrane properties. 1. Amiodarone is a potent anti-arrhythmic drug with lipophilic properties. The intercalation of such a drug into the membrane of erythrocytes may alter their shape and have an impact on the flow properties of blood. We therefore studied the influence of... | general pathological conditions |
Purulent pericarditis and cardiac tamponade caused by Nocardia asteroides in mixed connective tissue disease. Pericardial nocardiosis is extremely rare, but may affect especially immunocompromised hosts. We describe the first reported case of purulent pericarditis with cardiac tamponade as the initial presentation of s... | cardiovascular diseases |
Comparison of neuropsychologic functioning and clinical indicators of neurotoxicity in long-term survivors of childhood leukemia given cranial radiation or parenteral methotrexate: a prospective study. We prospectively compared neuropsychologic functioning and clinical indicators of neurotoxicity in 49 consecutive chil... | neoplasms |
Treating systemic fungal infections in AIDS patients. Prolonging life against the odds. Fungal infections have become one of the major causes of death among immunocompromised patients, particularly patients with AIDS. Accurate and quick diagnosis is difficult; therefore, empirical therapy is often necessary. This scena... | nervous system diseases |
Indigenous cases of Lyme disease diagnosed in North Carolina. Between January 1984 and December 1989, 102 indigenous cases of Lyme disease were reported in North Carolina. Lyme disease was reported in each of the three major geographic regions of the state: mountain, piedmont, and coastal plain. One or more diagnoses w... | general pathological conditions |
Cirrhosis and portal hypertension in a patient with adult Niemann-Pick disease. A woman with known Niemann-Pick disease, type B, presented at age 33 with upper gastrointestinal bleeding, ascites, and peripheral edema. Evaluation showed massive hepatosplenomegaly, infiltration of the liver with Niemann-Pick cells, cirrh... | digestive system diseases |
Regurgitant jet size by transesophageal compared with transthoracic Doppler color flow imaging. Combined echocardiography and Doppler color flow mapping from transthoracic imaging windows has become the standard method for the noninvasive assessment of valvular regurgitation. This study compared regurgitant jet areas b... | cardiovascular diseases |
The role of adrenalectomy in Cushing's syndrome. Forty-four patients with Cushing's syndrome were treated by adrenalectomy between 1975 and 1989. Twenty patients had adrenal adenomas: 13 with obvious Cushing's syndrome and 7 whose disease was subclinical, detected after evaluation of an incidentally discovered adrenal ... | general pathological conditions |
Brachial-jugular polytetrafluoroethylene fistulas for hemodialysis. A retrospective analysis was made of 16 patients who had received a brachial-jugular polytetrafluoroethylene (PTFE) graft for hemodialysis. In four patients, the procedure was used to treat malfunctioning brachio-axillary fistulas due to long venous st... | general pathological conditions |
New horizons in management of hypothermia and frostbite injury. Diagnosing hypothermia requires a high index of suspicion. Restoring lost heat with careful attention to hemodynamics usually results in complete recovery. Frostbite is best treated by physicians who are cognizant of the pathophysiology of cold injury. Alt... | general pathological conditions |
Transient entrapment neuropathy of the posterior interosseous nerve in violin players. Eleven white male right handed violin players complained of transient muscular deficit of the extensor compartment of the left forearm during and after prolonged playing. This was associated with paraesthesiae and pain. Relief was ac... | nervous system diseases |
Normeperidine-induced seizures in hereditary coproporphyria. Seizures are common in acute exacerbations of hepatic porphyria, even though the etiology is not identified in most cases. We have reported a case of normeperidine-induced seizures in a patient with hereditary coproporphyria. Although meperidine is commonly u... | digestive system diseases |
Transduodenal sphincteroplasty with transampullary septectomy for stenosing papillitis. The papilla of Vater and its sphincter of Oddi, lying at the confluence of the bile and pancreatic ducts in man, have long been suspected as a source of upper abdominal pain. Enlarging the opening of the transpapillary segment of th... | digestive system diseases |
Terminal cancer care and patients' preference for place of death: a prospective study. OBJECTIVE--To assess the preference of terminally ill patients with cancer for their place of final care. DESIGN--Prospective study of randomly selected patients with cancer from hospital and the community who were expected to die wi... | general pathological conditions |
Cerebrospinal fluid as a reflector of central cholinergic and amino acid neurotransmitter activity in cerebellar ataxia. Cerebrospinal fluid (CSF) amino acid neurotransmitters, related compounds, and their precursors, choline levels, and acetylcholinesterase activity were measured in the CSF of patients with cerebellar... | nervous system diseases |
Prevention of deep-vein thrombosis and pulmonary embolism after total hip replacement. Comparison of low-molecular-weight heparin and unfractionated heparin. In a prospective, randomized, double-blind study, the efficacy and safety of a low-molecular-weight heparin were compared with those of unfractionated sodium hepa... | general pathological conditions |
Peptide inhibition of neointimal hyperplasia in vein grafts. Angiopeptin, a novel synthetic octapeptide, was evaluated as a new approach toward the inhibition of neointimal hyperplasia in vein grafts. Male New Zealand white rabbits (n = 22) underwent carotid artery interposition bypass grafting with autologous reversed... | general pathological conditions |
Magnetic motor-evoked potentials in epilepsy: effects of the disease and of anticonvulsant medication. Magnetic motor-evoked potentials were recorded in 53 patients with medically intractable, mainly temporal lobe epilepsy and compared with potentials of 110 healthy volunteers. The motor-evoked potentials were reevalua... | nervous system diseases |
Acquired von Willebrand's syndrome. Therapeutic and diagnostic implications. Acquired von Willebrand's syndrome is a newly recognized bleeding diathesis thought to be caused by autoantibodies to the von Willebrand factor. Acquired von Willebrand's syndrome has been reported in association with lymphoproliferative disor... | neoplasms |
Retroviral transformation of cerebral microvascular endothelial cells: macrophage-like and microvascular endothelial cell properties. We report that L-cell-conditioned medium (LCM) transforms porcine cerebral microvascular (PCMV) endothelial cells into cells with macrophage-like properties. LCM is known to contain both... | neoplasms |
Does the treatment of genital condylomata in men decrease the treatment failure rate of cervical dysplasia in the female sexual partner? Three hundred ninety women treated for cervical dysplasia by local tissue ablation were studied retrospectively to test the hypothesis that the treatment failure rate is lower if the ... | neoplasms |
Alterations of adrenoceptors in the nasal mucosa of allergic patients in comparison with nonallergic individuals. Nasal hyperreactivity in nasal allergy may be due to changes of the characteristics in adrenergic receptors. Radioligand receptor-binding studies with the antagonists, 3H-prazosin (alpha 1-adrenoceptor), 3H... | general pathological conditions |
Colonic motor activity in acute colitis in conscious dogs. The changes in motor activity of the colon during acute colitis were investigated in six conscious dogs. The motor activity was recorded with seven strain-gauge transducers. Colitis was induced in the entire colon by luminal perfusion of acetic acid. The dogs e... | general pathological conditions |
Neutrophil dysfunction in glycogen storage disease Ib: association with Crohn's-like colitis. Two cases of patients with Crohn's-like colitis and glycogen storage disease Ib have been reported previously. In the current report, chronic inflammatory bowel disease that developed in another adolescent with this glycogenos... | digestive system diseases |
Percutaneous transhepatic cholecystostomy for acute complicated cholecystitis in elderly patients. We report our experience with percutaneous transhepatic cholecystostomy in 10 elderly patients with acute cholecystitis, complicated by empyema formation. Most of these patients has severe underlying disease, rendering th... | general pathological conditions |
A dentofacial deformity associated with incontinentia pigmenti: report of a case. A case of IP in a 16-year-old girl has been presented. This patient manifested classic ectodermal and mesodermal anomalies. We present this case to illustrate a rare etiologic factor in the development of dentofacial deformities that can ... | general pathological conditions |
Abnormal cardiac sensitivity in patients with chest pain and normal coronary arteries. The causes of chest pain in patients found to have angiographically normal coronary arteries during cardiac catheterization remain controversial. Cardiac sensitivity to catheter manipulation, pacing at various stimulus intensities an... | digestive system diseases |
Is emotional disturbance a precipitator or a consequence of chronic pain? The present study examined the relationship between psychological factors and pain in order to assess the contribution of emotional disturbance to the perpetuation of pain. A group of 163 chronic pain suffers in multiple settings was compared wit... | nervous system diseases |
A simple stress test for the evaluation of hypothalamic-pituitary-adrenal axis during the first 6 months of life. In 33 normal infants, divided into 3 age groups (less than 1 month, 1-3 months, and 3-6 months) plasma cortisol was measured at 2230, 2300, and 2330 h. Baseline plasma cortisol at 2230 h. was, as expected, ... | general pathological conditions |
Venous and arterial thrombosis in patients who received adjuvant therapy for breast cancer. The records of 2,673 patients randomized according to seven consecutive Eastern Cooperative Oncology Group (ECOG) studies of adjuvant therapy for breast cancer were reviewed for the occurrence of vascular complications. All prot... | neoplasms |
A high prevalence of antibody to the hepatitis C virus in patients with hepatocellular carcinoma in Japan. In Japan, hepatocellular carcinoma (HCC) is one of the most prevalent cancers, with a reported fatality rate showing a consistent and significant increase in the last decade. At most, only 25% of HCC cases are pos... | neoplasms |
Kearns-Sayre syndrome presenting as renal tubular acidosis. Renal tubular acidosis and tetany were the 1st manifestations of Kearns-Sayre syndrome in a 5-year-old child. Subsequently, he developed progressive external ophthalmoplegia, ptosis, retinopathy, heart block, and endocrinopathy. There was a 7.5-kb deletion of ... | general pathological conditions |
Rehabilitation of chronic stroke patients: changes in functional performance. Forty stroke patients who were at least one year post-onset completed a one-month intensive rehabilitation program. The month before the program served as a control period. During the program, patients received individual sessions in occupati... | nervous system diseases |
Enteroaggregative Escherichia coli elaborate a heat-stable enterotoxin demonstrable in an in vitro rabbit intestinal model. Enteroaggregative Escherichia coli (EAggEC) have been associated with persistent diarrhea in young children, but little is known about its pathogenesis. We assayed for enterotoxic activity in cult... | digestive system diseases |
Neoadjuvant Cis-DDP in esophageal cancers: an experience at a regional cancer centre, India. We are analysing the results of 80 patients who underwent surgery during 1983-84 for esophageal cancer. Forty patients who received pre-operative single agent Cis-DDP were grouped under "A" and 40 patients who went for surgery ... | neoplasms |
Causes of death in hospitalized intravenous drug abusers. The authors reviewed at autopsy the causes of death of 274 patients with evidence of intravenous drug abuse who had been admitted to a large public hospital. There were 127 who died from diseases unrelated to intravenous drug abuse, and in 41% of these, chronic ... | cardiovascular diseases |
Rupture of the oesophagus during cricoid pressure Rupture of the oesophagus occurred during the application of cricoid pressure at induction of anaesthesia when the patient vomited. The patient, who was bleeding from a gastric ulcer, was found to have a lower oesophageal tear which, although repaired at operation, resu... | digestive system diseases |
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