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Lack of prognostic value of syncope in patients with Wolff-Parkinson-White syndrome Syncope in patients with Wolff-Parkinson-White syndrome may be considered a premonitory event heralding the future development of sudden death. Therefore, the clinical and electrophysiologic data of 101 patients with Wolff-Parkinson-Whi... | nervous system diseases |
Haemangiopericytoma of the temporal bone. Haemangiopericytoma is an uncommon vascular tumour with a widespread distribution. Although meningeal involvement is well recognized, only a few sporadic cases of temporal bone lesions have been documented, all with doubtful sites of origin. Late presentation together with the ... | neoplasms |
Ocular rosacea. A histologic and immunopathologic study. Acne rosacea is an idiopathic dermatologic disease that frequently produces conjunctival inflammation. The authors studied the histology and immunopathology of epibulbar conjunctival biopsy specimens from eight patients with ocular rosacea and compared the findin... | general pathological conditions |
Intradural chordoma of the tentorium cerebelli. Case report. A rare case of intradural chordoma is described. The literature contains seven examples of intradural extraosseous chordoma, all reported in a ventral location. This is the first reported case of a primary intradural chordoma distant from the clivus and invol... | general pathological conditions |
Surgical indication for aortic arch hypoplasia in infants. To determine the surgical indications for aortic arch hypoplasia, the distal arch outer diameter, distal arch index (ratio of the distal arch diameter to the normal aortic ring diameter), and postoperative pressure gradient across the aortic arch were studied i... | cardiovascular diseases |
Effect of hydrocele on testis and spermatogenesis. One hundred and twenty cases of big unilateral hydrocele of the tunica vaginalis testis have been studied to ascertain the effect on the structure and function of the testis, taking the normal side as control. There was no pressure effect from the hydrocele on the stru... | general pathological conditions |
Results and follow-up after percutaneous pulsed laser-assisted balloon angioplasty guided by spectroscopy BACKGROUND. Few data are available on the long-term outcome of patients who undergo laser-assisted balloon angioplasty for recanalization of occluded peripheral arteries. Because the cost of laser angioplasty is hi... | general pathological conditions |
Role of xanthine oxidase and neutrophils in ischemia-reperfusion injury in rabbit lung. This study evaluated the effect of ischemia-reperfusion (I-R) on pulmonary capillary permeability in isolated rabbit lungs and the roles of xanthine oxidase (XO), aldehyde oxidase (AO), and neutrophils (PMN) in producing this lung i... | general pathological conditions |
Cerebrospinal fluid flow dynamics in children with external ventricular drains. Fifty-five children had 64 external ventricular drains (EVDs) placed predominantly (95%) for cerebrospinal fluid (CSF) shunt infections. In 9 children, a computer monitoring system measured the CSF output each second continuously for up to ... | nervous system diseases |
Neuropsychological profile linked to low dopamine: in Alzheimer's disease, major depression, and Parkinson's disease. A distinct pattern of neuropsychological deficits was associated with low homovanillic acid (HVA) in the cerebrospinal fluid of 21 patients with: Alzheimer's disease (9), Parkinson's disease (8) and maj... | general pathological conditions |
Is hyperglycemia associated with cardiovascular disease? The Framingham Study. The association of nonfasting blood glucose levels with CVD incidence was determined prospectively in 1382 men and 2094 women aged 45 to 84 years participating in the Framingham Heart Study. For this study, all patients were classified in 19... | cardiovascular diseases |
Intrahepatic cholesterol stones: a rationale for dissolution therapy. A case of primary cholesterol hepatolithiasis is reported. Stone composition was documented by infrared spectroscopy, and the presence of cholesterol saturated bile was demonstrated using standard biochemical techniques. The patient was treated with ... | digestive system diseases |
Laparoscopic pelvic lymphadenectomy in the staging of early carcinoma of the cervix. Laparoscopic pelvic lymphadenectomy was performed in 39 patients. An incision of the peritoneum between the round and infundibulo-pelvic ligament on each side gave access to the retroperitoneal space. Subsequently, laparoscopic surgery... | neoplasms |
Practical aspects of pulsatile gonadotropin-releasing hormone administration. Pulsatile administration of gonadotropin-releasing hormone represents a major advance in the treatment of anovulation in women who fail to ovulate with clomiphene citrate and is an alternative for many women who currently receive human menopa... | nervous system diseases |
Differentiation in embryonal neuroepithelial tumors of the central nervous system. Ninety-six embryonal neuroectodermal tumors were studied histologically and immunohistologically with a panel of antibodies including glial, neuronal, epithelial, mesodermal, and myelin markers. In 71 tumors there was glial and neuronal ... | neoplasms |
Purification and characterization of an inhibitor (soluble tumor necrosis factor receptor) for tumor necrosis factor and lymphotoxin obtained from the serum ultrafiltrates of human cancer patients. Serum ultrafiltrates (SUF) from human patients with different types of cancer contain a blocking factor (BF) that inhibits... | neoplasms |
A possible role for antiphospholipid antibodies in acquired cardiac valve deformity. We studied the frequency of antiphospholipid antibodies (aPL) in patients undergoing cardiac valve replacement, and present the results in the context of the pathology of the valve lesions. Forty-eight consecutive patients undergoing v... | general pathological conditions |
Immunity to and frequency of reinfection with respiratory syncytial virus. To better understand the duration of immunity against respiratory syncytial virus (RSV) and the role of serum antibodies to the surface glycoproteins, F and G, in susceptibility to reinfection, 15 adults with previous natural RSV infection were ... | general pathological conditions |
SPECT quantitation of iodine-131 concentration in phantoms and human tumors. The validity of SPECT measurement of iodine-131 (131I) concentration was tested in vitro in phantoms and in vivo by measuring bladder urine concentrations. Phantom studies comparing known and SPECT measured concentrations showed a good correla... | neoplasms |
Paraplegia after a routine lumbar laminectomy: report of a rare complication and successful management. Arachnoid cysts of the spinal canal are relatively common lesions that may be either intra- or extradural. These cysts are usually asymptomatic but may produce symptoms by compressing the spinal cord or nerve roots. ... | general pathological conditions |
Recurrent acute glomerulonephritis. Biopsy-proven recurrent acute glomerulonephritis (AGN) is extremely rare and is usually seen in children with acute, well-defined streptococcal infections. We present here a patient with recurrent AGN in the absence of chronic bacterial infection. The subject, an 80-year-old man, had... | general pathological conditions |
Sustained reduction in valvular regurgitation and atrial volumes with tailored vasodilator therapy in advanced congestive heart failure secondary to dilated (ischemic or idiopathic) cardiomyopathy. Afterload reduction therapy can acutely improve hemodynamic function in patients with advanced heart failure; however, it ... | cardiovascular diseases |
Hyperdynamic circulation in cirrhosis: a role for nitric oxide? Hypotension, low systemic vascular resistance, and a reduced sensitivity to vasoconstrictors are features of cirrhosis. These cardiovascular changes might be the result of increased synthesis of a vasodilator. Nitric oxide (NO), a potent vasodilator, is sy... | digestive system diseases |
Massive hemorrhage from an arterioureteral fistula associated with chronic renal transplant failure. A case of arterioureteral fistula from the graft artery stump of a failed transplant and the native ureter is reported. This case illustrates one of the possible complications of graft anastomosis. The etiological facto... | cardiovascular diseases |
Radiographic detection of recurrent carious lesions associated with composite restorations. The greatest potential problem associated with posterior composite restoration is secondary caries detection. It is essential that secondary caries is detected as early as possible to enhance the prognosis for a successful treat... | general pathological conditions |
Radical resection for carcinoma of the ampulla of Vater. One hundred four consecutive patients who underwent radical resection for ampullary cancer between 1965 and 1989 were retrospectively reviewed. Frequent clinical findings included jaundice (67%), significant (greater than 10%) weight loss (42%), and anemia (27%).... | neoplasms |
Reproducibility of growth hormone testing procedures: a comparison between 24-hour integrated concentration and pharmacological stimulation. The purpose of this study was to compare the reproducibility of two approaches to the evaluation of GH secretion: the integrated concentration of GH (IC-GH), a physiological test ... | general pathological conditions |
Immunological differentiation between neuroborreliosis and multiple sclerosis. Neuroborreliosis, a tick-borne spirochaetosis of the central nervous system, is diagnosed by the presence of intrathecally synthesized Borrelia burgdorferi-specific antibodies. Multiple sclerosis and neuroborreliosis can show similarities in... | nervous system diseases |
Amiodarone versus bretylium for suppression of reperfusion arrhythmias in dogs. Reperfusion arrhythmias are an important complication of interventions to limit infarct size. Recently, amiodarone has been shown to be rapidly effective in suppressing sustained, incessant ventricular tachycardia and ventricular fibrillati... | general pathological conditions |
Crural artery bypass with adjunctive arteriovenous fistula. A modification in distal anastomosis. We carried out crural artery bypass with an adjunctive arteriovenous fistula in 8 lower extremities of 7 patients with severe ischemic symptoms and poor distal run-off. Mean blood flow rates in the implanted grafts ranged ... | cardiovascular diseases |
Retinal infarction during sleep and wakefulness. Brain and retinal infarctions during sleep have been attributed to focal hypoperfusion caused by systemic hypotension combined with underlying arterial stenosis, rather than to embolism. Because some retinal emboli may be visualized on ophthalmoscopy, we studied 24 conse... | nervous system diseases |
Thromboxane A2 biosynthesis in acute asthma and after antigen challenge. Thromboxane A2 is a potent bronchial smooth muscle spasmogen in vitro, and it has been implicated in airway inflammation and in the genesis of bronchial hyperresponsiveness in asthma. We have examined the urinary excretion of a variety of products... | general pathological conditions |
A forme fruste of Marfan's syndrome: case history. A thirty nine year old woman presented with multiple aneurysms and dissections of the arterial system secondary to cystic medial necrosis is presented. After assessment of the family history a diagnosis of a forme fruste of Marfan's syndrome was made. Preoperative cons... | cardiovascular diseases |
Effects of doxazosin on serum lipids: a review of the clinical data and molecular basis for altered lipid metabolism. The goal of antihypertensive treatment must be not only the reduction of high blood pressure, but also the effective management of elevated cholesterol levels and other risk factors of coronary heart di... | cardiovascular diseases |
Expression of insulin-like growth factor II, alpha-fetoprotein and hepatitis B virus transcripts in human primary liver cancer. Insulin-like growth factor II is a fetal growth factor structurally and functionally related to insulin and insulin-like growth factor I. Its mRNA expression is developmentally regulated in hu... | neoplasms |
Risk of myocardial infarction and death during treatment with low dose aspirin and intravenous heparin in men with unstable coronary artery disease. The RISC Group 796 men with unstable coronary artery disease (unstable angina or non-Q-wave myocardial infarction [MI] ), were randomised to double-blind placebo-controlle... | cardiovascular diseases |
Coronary arterial remodeling studied by high-frequency epicardial echocardiography: an early compensatory mechanism in patients with obstructive coronary atherosclerosis. Coronary arterial remodeling is a compensatory mechanism that may limit the adverse effects of coronary obstructive lesions by expansion of the entir... | cardiovascular diseases |
Pyloric deformation from peptic disease. Radiographic evidence for incompetence rather than obstruction. We have used double-contrast radiographic techniques to clarify what changes in the configuration and movements of the gastroduodenal junction result when peptic lesions involve the distal gastric segment between th... | digestive system diseases |
Evidence against leukotrienes as mediators of brain edema. Leukotrienes are powerful metabolites of arachidonic acid which are known to increase the permeability of peripheral blood vessels. These substances are found in brain tissue in association with cerebral ischemia, and in brain tumors. Therefore, it has been pro... | nervous system diseases |
Effects of felodipine on urinary albumin excretion and metabolic control in hypertensive non-insulin-dependent diabetics. The effect of a blood pressure reduction by 10 mg extended release felodipine once daily on urinary albumin excretion (UAE) as well as the possible diabetogenic effect of felodipine was studied. A 2... | cardiovascular diseases |
Activation of early events of the mitogenic response by a P2Y purinoceptor with covalently bound 3'-O-(4-benzoyl)-benzoyladenosine 5'-triphosphate. 3'-O-(4-Benzoyl)benzoyl-ATP (BzATP), a photoaffinity analog of ATP, was used as a ligand for a P2Y purinoceptor (adenine nucleotide receptor) present in intact Swiss 3T3 an... | neoplasms |
Xeroderma pigmentosum: review and report of a case. Xeroderma pigmentosum is a rare inherited dermatosis that provides insight into the basic mechanism of carcinogenesis. It is a model disorder linking defective DNA repair with clinical abnormalities and neoplasia. UV light-induced damage to the skin begins early and r... | neoplasms |
Thallous chloride uptake and DNA profile in parathyroid adenomas. Thallium isotope scintigraphy is used to localize parathyroid adenomas but the mechanism underlying the technique is poorly understood. While larger adenomas are reliably localized the results are less certain for small tumours. This study explores the r... | neoplasms |
Primary abscess of the omentum. A 65-yr-old man presented with upper abdominal pain and fever due to a primary abscess of the omentum. The finding of microscopic-size foreign particles within the abscess raised the possibility of antecedent clinically silent perforation of the bowel or appendix. Surgical resection and ... | general pathological conditions |
Lesions of the mid-shaft of the humerus presenting as shoulder capsulitis. We describe three patients who presented with pain and restriction of movement at the shoulder suggestive of capsulitis, but proved to have lesions of the mid-shaft of the humerus. It is important to be aware of the possibility of this cause of ... | nervous system diseases |
Morphological observations late (greater than 30 days) after clinically successful coronary balloon angioplasty. This report describes clinical, morphological, and histological findings late (1.6-24.1 months [average, 8.2 months]) after clinically successful coronary balloon angioplasty in 20 necropsied patients with c... | cardiovascular diseases |
Autopsy-documented cure of multiple myeloma 14 years after M2 chemotherapy. Multiple myeloma was diagnosed in a 65-year-old woman in 1974 who thereafter received five-drug M2 chemotherapy. All protein abnormalities subsequently returned to normal and serial bone marrow studies documented complete bone marrow remission.... | neoplasms |
IgG and IgA antibodies to the collagen-like region of C1q in rheumatoid vasculitis. We investigated the presence of IgG and IgA antibodies to C1q in serum samples from 80 patients with rheumatoid arthritis (RA), 31 patients with rheumatoid vasculitis, and 80 healthy controls. IgG and IgA antibodies to C1q, as measured ... | cardiovascular diseases |
The value of intubating and paralyzing patients with suspected head injury in the emergency department. One hundred consecutive trauma patients who underwent planned emergency intubation with muscle paralysis in the ED were studied to investigate the safety of these procedures and to determine their impact on the evalu... | nervous system diseases |
Somatosensory-evoked potential monitored during total hip arthroplasty. One hundred consecutive patients were monitored using somatosensory-evoked potential (SEP) monitoring to detect intraoperative sciatic nerve compromise during total hip arthroplasty. The peroneal nerve was stimulated using the contralateral extremi... | general pathological conditions |
Combined anterior and posterior fusion for spinal deformity in myelomeningocele. Since 1973, 50 of 54 children have been treated by the author with a combined anterior and posterior fusion. Twenty males and 34 females, ranging in age from 1 to 16 years, have been followed for a mean period of 5.5 years. Sixteen patient... | general pathological conditions |
Monitoring the effect of CPAP on left ventricular function using continuous mixed-blood saturation. The hypothetic benefit of CPAP on cardiac performance and on a reduction in VO2 was tested in a patient before heart transplantation after acute myocardial infarction using continuous SvO2 monitoring. The CPAP added to i... | cardiovascular diseases |
Complications in the use of sodium hypochlorite during endodontic treatment. Report of three cases. In endodontic treatment, solutions of sodium hypochlorite are widely used as an irrigating agent. It is an effective solvent of both necrotic and vital tissues, which makes it toxic to the surrounding tissues. Complicati... | general pathological conditions |
Mortality in acute stroke with atrial fibrillation. The Italian Acute Stroke Study Group. We compared 211 consecutive patients who had acute ischemic hemispheric stroke and atrial fibrillation with 837 consecutive patients who had stroke without atrial fibrillation. The atrial fibrillation group included a higher frequ... | nervous system diseases |
Measuring the quality of care for the cancer patient. In recent years, the efforts to better define quality of patient care have focused on attempts to improve on the measurement of quality. These efforts raise three questions: (1) Why attempt to measure quality? (2) What is the best way to measure quality of care of t... | neoplasms |
Randomised single blind trial to compare the toxicity of subconjunctival gentamicin and cefuroxime in cataract surgery. Comparatively little attention has been paid to the conjunctival toxicity of antibiotics administered at the time of cataract surgery. We have observed the effect of subconjunctival gentamicin and cef... | cardiovascular diseases |
Thrombolytic therapy for noncoronary diseases. Thrombolytic therapy has been used fairly extensively in the management of acute proximal deep-vein thrombophlebitis of the extremities, acute pulmonary embolism, and acute peripheral arterial thrombosis and embolism in addition to acute thrombotic coronary events. In the ... | nervous system diseases |
The pharmacist as a health consultant--ten years later. Pharmacists remain a readily accessible and trusted source of information about health. In order to assess the quality of counseling on health matters and the progress of the profession in this activity over the last decade, a study similar to one reported in 1978... | digestive system diseases |
Recurrent pigmented melanocytic nevus. A benign lesion, not to be mistaken for malignant melanoma. Melanocytic nevi that recur after incomplete removal are pigmented lesions that may clinically and pathologically simulate malignant melanoma in situ. Five examples of recurrent pigmented melanocytic nevus, with emphasis ... | neoplasms |
Antagonism of serotonin S3 receptors with ondansetron prevents nausea and emesis induced by cyclophosphamide-containing chemotherapy regimens The control of nausea and emesis in cancer patients receiving chemotherapy poses a significant management problem. In this randomized, double-blind, placebo-controlled study, we ... | digestive system diseases |
Left ventricular mechanics of ejecting, postischemic hearts during left ventricular circulatory assistance. We measured the effects of left ventricular circulatory assistance on ventricular mechanics of ejecting sheep hearts before and after global ischemia. Flows from left atrium to femoral artery ranged between 20 an... | cardiovascular diseases |
Neonatal calves develop airflow limitation due to chronic hypobaric hypoxia. Neonates and infants presenting with pulmonary hypertension and chronic hypoxia often exhibit airway obstruction. To investigate this association, we utilized a system in which neonatal calves are exposed to chronic hypobaric hypoxia and devel... | general pathological conditions |
Comparative studies of DU-PAN-2, carcinoembryonic antigen, and CA19-9 in the serum and bile of patients with pancreatic and biliary tract diseases: evaluation of the influence of obstructive jaundice. The levels of DU-PAN-2 antigen, carcinoembryonic antigen, and CA19-9 in serum and bile of patients with pancreatic and ... | general pathological conditions |
Arterial protection: a neglected but crucial therapeutic goal. Hypertension is accompanied by 2 major types of arterial pathologic conditions: smooth muscle hypertrophy of arteriolar resistance vessels and atherosclerosis, primarily involving the larger arteries. Smooth muscle hypertrophy may develop either as a second... | general pathological conditions |
Epidemiology of epilepsy in Guaymi Indians from Bocas del Toro Province, Republic of Panama. This cross-sectional study was conducted to describe the epidemiology of epilepsy in Guaymi Indians residing in Changuinola, a small town on Panama's Caribbean coast near Costa Rica. We randomly selected households and attempte... | nervous system diseases |
The National Cholesterol Education Program: guidelines, status, and issues. The 1987 report of the Adult Treatment Panel (ATP) of the National Cholesterol Education Program (NCEP) was concerned with who should be treated for high blood cholesterol levels and how they should be treated. Total cholesterol levels were cla... | cardiovascular diseases |
Skin ultrasound in dermatologic surgical planning. High-resolution ultrasonography was performed on 55 patients with palpable skin lesions, all submitted to surgical excision and to histologic diagnosis. In all the cases, the ultrasound picture was confirmed by the surgical appearance of the lesions. The sonographic st... | neoplasms |
Keratin subsets in spindle cell sarcomas. Keratins are widespread but synovial sarcoma contains a distinctive keratin polypeptide pattern and desmoplakins. The presence of individual keratin polypeptides and desmoplakins was immunohistochemically studied in 25 spindle cell sarcomas of different types using acetone-fixe... | neoplasms |
Appendectomy in primary and secondary staging operations for ovarian malignancy. Appendectomy was performed at primary or secondary staging operations in 100 patients with ovarian malignancies. Of 80 patients who underwent appendectomy at the time of their primary surgery, 25 (31.2%) had appendiceal metastases. Among 4... | digestive system diseases |
Pneumocephalus secondary to a high-pressure water injury to the nose. We report a case of pneumocephalus following a water jet injury to the nose incurred during a water-skiing fall. Pneumocephalus due to this type of injury has not been previously reported, to our knowledge. Since this unusual injury may be associated... | nervous system diseases |
Restenosis after balloon angioplasty. A practical proliferative model in porcine coronary arteries. A model of proliferative human restenosis was developed in domestic pigs by using deep injury to the coronary arterial media. Metal wire coils were delivered percutaneously to the coronary arteries of 11 pigs with an ove... | cardiovascular diseases |
Cup containment and orientation in cemented total hip arthroplasties. We reviewed the radiographs of 864 Charnley and STH (Zimmer) cemented total hip arthroplasties with a mean follow-up of seven years (maximum 16 years). Survivorship analysis was used to assess the correlation between radiographic performance and the ... | general pathological conditions |
Severe hypotension due to intramyometrial injection of prostaglandin E2 Treatment of postpartum haemorrhage because of uterine atony with intramyometrial prostaglandin E2 1 mg, in an anaesthetised patient resulted in life-threatening hypotension. Anaesthetists should be aware of the potential cardiovascular side effect... | cardiovascular diseases |
Evolution of the continuity equation in the Doppler echocardiographic assessment of the severity of valvular aortic stenosis. The use of Doppler techniques has greatly enhanced the noninvasive ultrasound technique for evaluation of valvular aortic stenosis. M-mode and two-dimensional echocardiography could not reliably... | cardiovascular diseases |
A monoclonal antibody against the CD18 leukocyte adhesion molecule prevents indomethacin-induced gastric damage in the rabbit. The role of leukocyte adherence in the mechanism of gastropathy induced by nonsteroidal antiinflammatory drugs was investigated using a rabbit model. Gastric damage was induced by intragastric ... | general pathological conditions |
Does cholesterol screening result in negative labeling effects? Results of the Massachusetts Model Systems for Blood Cholesterol Screening Project. Several previous studies that looked at the effects of labeling individuals as hypertensive found increases in psychosocial distress, diminished feelings of well-being, or ... | cardiovascular diseases |
Aerobic work capacity in patients with chronic fatigue syndrome OBJECTIVE--To determine the aerobic work capacity of patients with the chronic fatigue syndrome and compare it with that of two control groups, and to assess the patients' perception of their level of activity before and during illness. DESIGN--A symptom l... | digestive system diseases |
Scintigraphic measurement of oropharyngeal transit in man. Scintigraphic studies of the oropharyngeal transit of a liquid bolus were performed in 15 healthy controls, 12 patients with symptoms of oral-pharyngeal dysphagia, and 13 patients with neuromuscular disease, who did not have dysphagia. Gamma camera imaging of t... | nervous system diseases |
Diabetes mellitus and hypertension. Hypertension and diabetes mellitus are chronic medical conditions that frequently coexist. In the United States, it is estimated that 10 million persons suffer from diabetes mellitus, 60 million from hypertension, and 3 million from the combination of the two. There may be a causal r... | cardiovascular diseases |
GTPase-activating protein interactions with the viral and cellular Src kinases. GTPase-activating protein (GAP), which regulates the activities of Ras proteins, is implicated in mitogenic signal transduction by growth-factor receptors and oncoproteins with tyrosine kinase activity. Oncogenic viral Src (p60v-src) encode... | general pathological conditions |
Identification of herpes simplex virus DNA in lesions of erythema multiforme by the polymerase chain reaction. An association between erythema multiforme and herpes simplex virus infection has been supported by clinical studies and by the detection by immunofluorescence of herpes viral antigen in sera and skin biopsy s... | general pathological conditions |
Total hip arthroplasties in patients younger than 45 years. A nine- to ten-year follow-up study. Eighty-one cemented total hip arthroplasties in patients younger than 45 years were reviewed with an average 9.2-year follow-up interval. The results were compared with the same group previously reported at an average follo... | general pathological conditions |
Silent myocardial ischemia and infarction in diabetics with peripheral vascular disease: assessment by dipyridamole thallium-201 scintigraphy. We investigated the incidence of silent myocardial ischemia and infarction as assessed by dipyridamole thallium scintigraphy in 30 diabetic patients with peripheral vascular dis... | cardiovascular diseases |
Clinical and anatomic considerations for surgery in femoropopliteal disease and the results of surgery. From 1980 to 1988 we performed 288 femoropopliteal bypass operations in 231 patients at the Oregon Health Sciences University. The indication for the procedure was claudication in 31% and the relief of limb-threateni... | cardiovascular diseases |
Otogenic Fusobacterium necrophorum meningitis. A case of meningitis secondary to acute suppurative otitis media in a previously healthy child is reported. The only organism isolated from blood after aerobic and prolonged anaerobic culture was identified as Fusobacterium necrophorum. Complete recovery followed treatment... | nervous system diseases |
Hindbrain ischemia produced by bilateral vertebral artery occlusion and moderate hypotension in spontaneously hypertensive rats. Hindbrain ischemia was induced by bilateral vertebral artery occlusion and moderate hypotension in spontaneously hypertensive rats (SHRs). Mean arterial blood pressure was lowered to 80 mmHg ... | cardiovascular diseases |
Study of preneoplastic changes of liver cells by immunohistochemical and molecular hybridization techniques. The status of hepatitis B virus DNA was investigated by in situ hybridization in multifocal areas of a noncancerous hepatitis B virus-associated cirrhosis. This liver exhibited a marked degree of dysplasia and a... | digestive system diseases |
Continent ileocolonic urinary reservoirs for filling and lining the post-exenteration pelvis. Pelvic exenteration has a high complication rate due, in large part, to the extensive raw surfaces and dead space it creates. Numerous techniques have been used to control this space and line these surfaces, but none, to date,... | neoplasms |
The use of L-dopa and carbidopa in metastatic malignant melanoma. A combination of L-dopa and carbidopa was given orally to 17 patients with metastatic melanoma. Maximum tolerated oral doses were given, up to 4 grams daily. No response was seen in 15 patients evaluable for response. Toxicity was considerable, with seve... | neoplasms |
Serial immunocytologic analysis of blood for tumor cells in two patients with neuroblastoma. Tumor surveillance tests are used to determine whether malignant cells are responsive or resistant to therapeutic regimens. For patients with neuroblastoma, conventional methods of surveillance are not sensitive enough. Because... | neoplasms |
Multiple orbital tumors were cavernous hemangiomas. Two distinct masses in the left orbit were incidentally found in a 48-year-old woman during a computed tomographic scan done to evaluate neurologic complaints. Initial diagnostic considerations focused on a lymphoproliferative disorder or other systemic disease. Orbit... | cardiovascular diseases |
Primary sarcomas of the major salivary glands. Sarcomas arising in the major salivary glands are rare. This article presents the clinicopathologic features of 11 patients with primary sarcomas of the parotid gland (eight men and three women aged 7 to 75 years; mean age, 42 years). The 11 sarcomas were histologically ty... | neoplasms |
Definitive mandibular replacement using reconstruction plates. Mandibular defects following radical cancer surgery continue to provide challenges to head and neck surgeons. Twenty-seven patients with advanced oral cancer underwent primary mandibular replacement with metal reconstruction plates without the use of bone. ... | general pathological conditions |
Prospective study of quality of life before and after coronary artery bypass grafting OBJECTIVES--Measurement of changes in patients' perceptions of how differing states of health affect their lives and determination of the ability of preoperative variables to predict outcome after coronary artery bypass grafting. DESI... | cardiovascular diseases |
Colonoscopy during an attack of severe ulcerative colitis is a safe procedure and of great value in clinical decision making. Thirty-four patients who had severe ulcerative colitis had a colonoscopic examination during the attack. The indications were resistance to therapy and/or differential diagnostic purposes. Total... | digestive system diseases |
Remitting seronegative symmetrical synovitis with pitting oedema in young adults: a subset of rheumatoid arthritis or a distinct syndrome? Three young adult patients with seronegative symmetrical polysynovitis affecting the peripheral joints with pitting oedema of both dorsum of hands and feet are described. All of the... | general pathological conditions |
Shortcut method to calculate the sample size in trials of screening for chronic disease. One of the first questions arising in the planning of a randomized trial to evaluate mortality reduction by screening concerns the sample size of the trial required to detect an expected mortality reduction in the study group for g... | general pathological conditions |
An evaluation of cocaine-induced chest pain STUDY OBJECTIVE: To determine if enzymatic evidence of acute myocardial injury is present in patients complaining of chest pain after cocaine use when the ECG is normal or nondiagnostic. DESIGN: Serial ECG and creatinine kinase (CK) and CK isoenzymes (CK-ISO) determinations w... | cardiovascular diseases |
A case of amnesia after excision of the septum pellucidum. Tumours of the septum pellucidum (SP) are rare and seldom associated with memory impairment either before or after operation. A patient is described who developed amnesia after transcallosal excision of a tumour of the SP. Radiology did not show any major lesio... | neoplasms |
Biobehavioral factors in Cardiac Arrhythmia Pilot Study (CAPS). Review and examination. The behavioral studies component of the multicenter Cardiac Arrhythmia Pilot Study (CAPS) was designed to examine the relation of biobehavioral factors and frequency of ventricular premature complexes (VPCs), efficacy of antiarrhyth... | cardiovascular diseases |
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