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Coronary artery anomalies in 126,595 patients undergoing coronary arteriography. Coronary artery anomalies were found in 1,686 patients (1.3% incidence) undergoing coronary arteriography at the Cleveland Clinic Foundation from 1960 to 1988. Of the 1,686 patients, 1,461 (87%) had anomalies of origin and distribution, an... | general pathological conditions |
Concordance for dyslipidemic hypertension in male twins. Sixty cases of dyslipidemic hypertension were identified in the 1028 middle-aged, white, male twin participants in the first examination of the National Heart, Lung, and Blood Institute Twin Study (1969 to 1973). The prevalence of dyslipidemic hypertension was si... | cardiovascular diseases |
Malignancy associated with chronic empyema: radiologic assessment. Radiologic findings of six cases of malignancy associated with chronic empyema 5-39 years in duration were reviewed. Pathologic examination confirmed three B-cell non-Hodgkin lymphomas, one round-cell sarcoma, one mesothelioma, and one adenocarcinoma. R... | general pathological conditions |
Recovery profile after desflurane-nitrous oxide versus isoflurane-nitrous oxide in outpatients. Thirty-eight healthy outpatients undergoing elective surgical procedures lasting 1-3 h were randomly assigned to receive either desflurane 3% (approximately 0.5 MAC) or isoflurane 0.6% (approximately 0.5 MAC) for maintenance... | general pathological conditions |
Risk factors for gestational diabetes in black population. In a long-term longitudinal study of gestational diabetes mellitus in Black women, risk factors that were identified were age, obesity, a family history of diabetes, and the presence of hypertension. Poor predictors were a history of a previous large-for-date i... | cardiovascular diseases |
Acute axonal polyneuropathy associated with anti-GM1 antibodies following Campylobacter enteritis. We report 2 patients with Guillain-Barre syndrome (GBS) following Campylobacter jejuni enteritis. Electrophysiologic studies indicated that the predominant process was axonal degeneration of motor nerves, and clinical rec... | digestive system diseases |
Expression of P-glycoprotein in adult T-cell leukemia cells. We have examined the expression of P-glycoprotein (P-gp) in adult T-cell leukemia (ATL) samples from 25 patients. Based on immunoblotting with a monoclonal antibody against P-gp, C219, 8 of 20 ATL patients were P-gp positive at the initial presentation. All 6... | neoplasms |
A phase II study of piritrexim in combination with methotrexate in recurrent and metastatic head and neck cancer. Thirty patients with recurrent and/or metastatic head and neck cancer were treated with sequentially administered methotrexate (MTX) and piritrexim (PTX). The treatment schedule consisted of intravenous (IV... | neoplasms |
Screening for neuroblastoma at 3 weeks of age: methods and preliminary results from the Quebec Neuroblastoma Screening Project. A large neuroblastoma screening study was recently started in the province of Quebec, Canada. This project, a collaboration between the Quebec Network for Genetic Medicine and the University o... | neoplasms |
Propranolol and the morning increase in sudden cardiac death: (the beta-blocker heart attack trial experience). To provide insight into the protective effect of propranolol on mortality after myocardial infarction observed in the beta-Blocker Heart Attack Trial, the time of occurrence of sudden cardiac death was examin... | general pathological conditions |
Vascularized full-thickness parietal bone grafts in maxillofacial reconstruction: the role of the galea and superficial temporal vessels. Reconstruction of bony structures of the face is always a problem as big as the defect and the function that must be replaced. Everything from simple grafts to sophisticated distant ... | nervous system diseases |
In vitro anticolon antibody production by mucosal or peripheral blood lymphocytes from patients with ulcerative colitis [published erratum appears in Gut 1991 Apr;32(4):460] Serum anticolon antibody and in vitro anti-colon antibody production by peripheral blood and mucosal lymphocytes was investigated in patients with... | neoplasms |
Coronary balloon angioplasty through diagnostic 6 French catheters. We investigated the use of ultralow profile balloon catheters (Scimed ACE, USCI Probe, Cordis, Orion) for coronary angioplasty through 6 French diagnostic catheters (Schneider, Cordis). Contrast injection was assisted with a Hercules pump (Cordis) in a... | cardiovascular diseases |
Stimulation of active renin release in normal and hypertensive pregnancy. 1. Active plasma renin concentration but not total renin concentration is reduced in women with pregnancy-induced hypertension compared with normotensive pregnant women. This study was conducted to determine whether women with pregnancy-induced h... | cardiovascular diseases |
Carbamazepine-induced antinuclear antibodies and systemic lupus erythematosus-like syndrome. A 20-year-old woman developed a systemic lupus erythematosus (SLE)-like syndrome and a positive antinuclear antibody (ANA) soon after initiation of carbamazepine (CBZ) therapy. Symptoms and serology became normal after CBZ was ... | nervous system diseases |
Cancer surveillance in ulcerative colitis. During a 13-year period, 213 patients with ulcerative colitis who had no clinical or endoscopic evidence of colonic carcinoma were enrolled in a biopsy surveillance program for dysplasia and carcinoma. The aims of the study were to determine whether such a program could decrea... | neoplasms |
Expression of class II molecules on intestinal epithelial cells in humans. Differences between normal and inflammatory bowel disease. Expression of class II antigens on human intestinal epithelial cells was assessed using a sensitive avidinbiotin-peroxidase technique. HLA-DR was present predominantly in the normal smal... | digestive system diseases |
In-hospital and 1-year mortality in 1,524 women after myocardial infarction. Comparison with 4,315 men. We determined in-hospital and 1-year prognoses after acute myocardial infarction (MI) in 5,839 consecutive patients derived from 14 of 21 coronary care units in Israel during 1981-1983. Age-adjusted in-hospital morta... | cardiovascular diseases |
Hair transplantation (a new method for recipient site suturing): the upper dermal running stitch. Recipient hair transplant plugs may heal into place with palpable, and unfortunately, visible borders. This appearance, called "cobblestoning," is reminiscent of the bumps in a cobblestone street. The author presents a new... | general pathological conditions |
The effect of sleep on the dyskinetic movements of Parkinson's disease, Gilles de la Tourette syndrome, Huntington's disease, and torsion dystonia. The effect of sleep on the involuntary movements or dyskinesias in Parkinson's disease, Huntington's disease, primary and secondary torsion dystonia, and Gilles de la Toure... | nervous system diseases |
Is routine preoperative hemodynamic evaluation of nonagenarians necessary? An Incidence of co-morbid cardiac disease in the elderly surgical patient as high as 66% has been previously reported. Even in the absence of clinically significant cardiac disease, advanced age alone is often considered sufficient indication fo... | general pathological conditions |
Botulinum treatment of childhood strabismus. Four hundred thirteen children ranging in age from 2 months to 12 years were treated for strabismus by botulinum injection of extraocular muscles. An average of 1.7 injections per patient was given. Follow-up at an average of 26 months after the last injection (minimum, 6 mo... | nervous system diseases |
Ventricular free-wall rupture after myocardial infarction. Treatment and outcome. Ventricular free-wall rupture remains one of the leading causes of death after myocardial infarction (MI). With increased abilities for diagnosis and resuscitation techniques, surgical correction of free-wall myocardial defects resulting ... | cardiovascular diseases |
Development and reversibility of T lymphocyte dysfunction in experimental obstructive jaundice This study evaluates the effect of experimental biliary obstruction by bile duct ligation (BDL) and biliary drainage on cell-mediated immunity in Wistar rats. Immune status has been assessed by a mitogen stimulation test of T... | general pathological conditions |
Cytologic features of poorly differentiated 'insular' carcinoma of the thyroid, as revealed by fine-needle aspiration biopsy. The authors report on the cytologic features of six cases of poorly differentiated "insular" carcinoma (IC) of the thyroid, a recently described variety of thyroid tumor intermediate between wel... | neoplasms |
Interventional gallbladder procedures. Interventional radiologic procedures in the gallbladder are influencing both the diagnosis and therapy of many gallbladder disorders. Current diagnostic and therapeutic percutaneous techniques offer important alternatives for their management. This article highlights the spectrum ... | digestive system diseases |
Spectral analysis of tremor: understanding the results. Spectral analysis of a tremor record can sometimes produce a spectrum with multiple components of significant amplitude. The problem is to determine whether the presence of several peaks represents the coexistence of separate tremor mechanisms or be a consequence ... | nervous system diseases |
Relation between transcardiac and transthoracic current during defibrillation in humans. Conceptually, transthoracic defibrillation threshold current can be considered a function of at least two quantities. It is directly proportional to the transcardiac threshold current and inversely proportional to the transcardiac ... | general pathological conditions |
Hypocalciuria of preeclampsia is independent of parathyroid hormone level. Hypocalciuria is a feature of preeclampsia. The roles of parathyroid hormone (PTH) and vitamin D 1,25(OH)2D3 (calcitriol) in its pathogenesis have not yet been determined. Fourteen preeclamptic women were compared with 12 women with chronic hype... | general pathological conditions |
Percutaneous cholangioscopic or transpapillary insertion of self-expanding biliary metal stents. Fifty-two self-expanding metal stents were implanted in 39 patients with malignant (35 patients) or benign (4 patients) biliary stenoses. The stents were inserted and properly released by means of a 7 or 9 French gauge deli... | neoplasms |
Small cell lung cancer: staging with MR imaging. Small cell lung cancer is an aggressive neoplasm; metastases are detected in two-thirds of patients at diagnosis with use of conventional staging, which includes bilateral bone marrow biopsy, bone scintigraphy, and computed tomography (CT) of the head and abdomen. In 25 ... | neoplasms |
Clustering of cancer in families of patients with primary lung cancer. We have previously shown that patients with a positive family history of lung cancer did not exhibit characteristics expected if the familial association was a surrogate for a genetic mechanism which was absent in those without such a history. In th... | neoplasms |
A randomized double-blind crossover comparison of four rate-responsive pacing modes. The aim of this study was to compare, both subjectively and objectively, four modern rate-responsive pacing modes in a double-blind crossover design. Twenty-two patients, aged 18 to 81 years, had an activity-sensing dual chamber univer... | cardiovascular diseases |
Clinical outcome of seriously ill surgical patients with intra-abdominal infection depends on both physiologic (APACHE II score) and immunologic (DTH score) alterations. The delayed-type hypersensitivity (DTH) response and the APACHE II score in 118 patients with surgical infections were measured prospectively and rela... | general pathological conditions |
Recurrence rate after discontinuation of long-term mebendazole therapy in alveolar echinococcosis (preliminary results). The recurrence rate was investigated in 19 patients with non-resectable alveolar echinococcosis after discontinuation of a long-term therapy with mebendazole (average treatment 4.3 years). A control ... | digestive system diseases |
Miller-Fisher syndrome and pontine abnormalities on MRI: a case report. The authors report a patient with Miller-Fisher syndrome in whom MRI of the brain stem showed increased signal density on T2 sequence anterior to the fourth ventricle, on the right and the left. The authors discuss the relation between these MRI ab... | general pathological conditions |
Emergency portosystemic shunt in patients with variceal bleeding. Thirty-five patients for whom emergency sclerotherapy or conservative treatment, or both, failed to arrest variceal bleeding, or who had early rebleeding and required emergency portosystemic shunts (EPSS) were studied. EPSS permanently controlled the var... | digestive system diseases |
Properties of strains of Escherichia coli O26:H11 in relation to their enteropathogenic or enterohemorrhagic classification. Thirty-seven strains of Escherichia coli O26:H11 from infants and calves with diarrhea were examined for properties associated with enteropathogenic (EPEC) or enterohemorrhagic E. coli (EHEC). St... | digestive system diseases |
Capillary hemangioma of the right main bronchus treated by sleeve resection in infancy. Respiratory distress developed in a 5-month-old female infant with roentgenographic evidence of hyperinflation of the right lung. Bronchoscopy revealed a vascular tumor extending from the medial wall of the right main bronchus leadi... | neoplasms |
Regulatory elements of the erythropoietin gene. Because the human hepatoma cell line Hep3B produces erythropoietin (Epo) in a regulated fashion, it can be used to investigate the cis-acting regulatory elements of the Epo gene. Comparison of primate and mouse sequences shows strong homology not only in the coding sequen... | general pathological conditions |
Therapy for acute infectious diarrhea in children. This article reviews current recommendations of therapy with antidiarrheal compounds and antimicrobial agents for acute infectious diarrhea in children. In most infants and children with acute infectious diarrhea, treatment with antidiarrheal compounds is not indicated... | general pathological conditions |
Transduodenal sphincteroplasty with transampullary septectomy for stenosing papillitis. The papilla of Vater and its sphincter of Oddi, lying at the confluence of the bile and pancreatic ducts in man, have long been suspected as a source of upper abdominal pain. Enlarging the opening of the transpapillary segment of th... | general pathological conditions |
Effect of a calcium-entry blocker, nicardipine, on intrarenal hemodynamics in essential hypertension. The effects of a calcium-entry blocker, nicardipine, on intrarenal hemodynamics were studied in essential hypertension. A 4-week study was performed in eight patients with essential hypertension who were given a regula... | cardiovascular diseases |
Myocyte cell loss and myocyte cellular hyperplasia in the hypertrophied aging rat heart. To determine the effects of age on the myocardium, the functional and structural characteristics of the heart were studied in rats at 4, 12, 20, and 29 months of age. Mean arterial pressure, left ventricular pressure and its first ... | general pathological conditions |
Endoscopic treatment of biliary tract strictures in sclerosing cholangitis: a larger series and recommendations for treatment. We report a group of 35 patients with primary sclerosing cholangitis who had long-term follow-up after endoscopic treatment of major ductal strictures in the primary or secondary biliary ducts.... | digestive system diseases |
Laparoscopic cholecystectomy using intracorporeal lithotripsy. Over a 13-month period (November 1988 to December 1989), we performed our first 104 laparoscopic cholecystectomies using an intracorporeal ultrasonic lithotripsy technique. The procedure in three of these patients was converted to an open operation because ... | digestive system diseases |
Simplified method for estimating true aortic valve mean gradient from simultaneous left ventricular and peripheral arterial pressure recordings. Estimation of the aortic valve gradient by simultaneous recording of left ventricular and peripheral arterial pressures is subject to error due to delay and modulation of the ... | cardiovascular diseases |
Adult hepatic fibropolycystic disease presenting as obstructive jaundice. Obstructive jaundice caused by compression of the common hepatic duct by a simple hepatic cyst in a 31 year old Europid man is reported. The jaundice and duct compression resolved after percutaneous aspiration of the cyst under ultrasound directi... | neoplasms |
Monitoring of spinal cord stimulation evoked potentials during thoracoabdominal aneurysm surgery. Repair of a thoracoabdominal aneurysm involves a significant risk of ischemic injury to the spinal cord. Standard monitoring of somatosensory evoked potentials, which relies upon peripheral nerve stimulation, becomes nonsp... | cardiovascular diseases |
Distribution of three alpha-chain beta-hexosaminidase A mutations among Tay-Sachs carriers. DNA from 176 carriers of the Tay-Sachs gene was tested for the presence of the three mutations most commonly found among Ashkenazi Jews: the so-called insertion, splice junction, and adult mutations. Among 148 Ashkenazi Jews tes... | nervous system diseases |
Lymph nodes in incipient adult T-cell leukemia-lymphoma with Hodgkin's disease-like histologic features. Lymph nodes were examined from four patients with incipient adult T-cell leukemia-lymphoma (ATLL) who had mild lymphadenopathy, fatigue, no or a few atypical lymphocytes in their peripheral blood, and integrated pro... | neoplasms |
Correlates of survival and the Daumas-Duport grading system for astrocytomas. In order to examine the correlation between prognosis and the histological features of nuclear atypia, mitosis, endothelial proliferation, and necrosis in supratentorial adult astrocytomas, the authors reviewed 251 such cases treated at the M... | neoplasms |
Hyperkalaemia during rapid blood transfusion and hypovolaemic cardiac arrest in children. A morbidity and mortality review documented a high occurrence of hyperkalaemia in cardiac arrests associated with rapid blood transfusion, which resulted in further study. In order to stimulate events during rapid blood transfusio... | general pathological conditions |
Post-caesarean section analgesia: a comparison of epidural butorphanol and morphine. Epidural butorphanol 1, 2 and 4 mg were compared with morphine, 5 mg, for postoperative analgesia in 92 consenting, healthy, term parturients who had undergone Caesarean section under epidural lidocaine anaesthesia in a randomized doub... | general pathological conditions |
Percutaneous mitral valvuloplasty in surgical high risk patients. Among 126 consecutive patients undergoing percutaneous mitral valvuloplasty, 34 were judged to be at high risk for surgery on the basis of age greater than 70 years (n = 13), New York Heart Association functional class IV (n = 11), ejection fraction less... | cardiovascular diseases |
Determination of hepatitis B virus DNA in serum using the polymerase chain reaction: clinical significance and correlation with serological and biochemical markers. Sera from 98 patients with various stages of chronic hepatitis B virus infection were studied to determine the clinical significance of hepatitis B virus D... | digestive system diseases |
Acinic cell carcinoma. Clinicopathologic review. The authors reviewed 90 cases of acinic cell carcinoma treated at the Mayo Clinic to assess long-term follow-up and to study features predictive of disease progression. Sixty-three patients (55 females and 35 males) were seen for primary treatment; 27 had recurrent disea... | neoplasms |
Pineal hyperactivity in spontaneously hypertensive rats: muscarinic regulation of indole metabolism. 1. Choline acetyltransferase activity and [3H]quinuclidinyl benzylate-binding sites were detected in the pineal gland of normotensive Wistar-Kyoto rats and of spontaneously hypertensive rats. 2. In vitro, muscarinic act... | cardiovascular diseases |
An in vitro evaluation of an artificial heart. Interactions between human blood and the Penn State Artificial Heart were examined in vitro to study the effects of various operating conditions on the hematologic response. A dual-loop recirculating flow system that accommodated human blood was developed and blood was sub... | cardiovascular diseases |
Pontine supranuclear facial palsy. Two patients presented with a unilateral supranuclear facial palsy. Additional dysarthria was attributed to the pontine origin documented by magnetic resonance imaging on the contralateral side. The pontine disorder also was indicated by an isolated delay of the blink reflex R1 compon... | general pathological conditions |
Buffered versus plain lidocaine as a local anesthetic for simple laceration repair. STUDY OBJECTIVE: Buffered lidocaine was compared with plain lidocaine as a local anesthetic for simple lacerations. DESIGN: Randomized, double-blind, prospective clinical trial. SETTING: Urban emergency department. TYPE OF PARTICIPANTS:... | general pathological conditions |
Systematic computer-aided search of optimal staging system for colorectal cancer. Two hundred and ninety-eight patients with curatively resected colorectal cancer were classified into 12 categories according to the depth of tumour penetration (T1-T4), and lymph node status (N0-N2). Using a computer, these categories we... | neoplasms |
Diagnostic fine-needle puncture of the gallbladder with US guidance From February 1988 to January 1990, 118 fine-needle diagnostic punctures of the gallbladder (DPG) were performed under continuous ultrasound (US) guidance on symptomatic patients with gallstones. The first attempt at gallbladder puncture and aspiration... | digestive system diseases |
Reversal of cardiac dysfunction secondary to type 1 primary hyperoxaluria after combined liver-kidney transplantation. A 23-year-old man with type 1 primary hyperoxaluria, renal failure, and oxalosis developed a severe cardiomyopathy while awaiting combined liver-kidney transplantation. This manifested as radiographic ... | cardiovascular diseases |
Babbling in the manual mode: evidence for the ontogeny of language. Infant vocal babbling has been assumed to be a speech-based phenomenon that reflects the maturation of the articulatory apparatus responsible for spoken language production. Manual babbling has now been reported to occur in deaf children exposed to sig... | nervous system diseases |
Retinal vasculitis as a complication of rheumatoid arthritis. Two middle-aged women developed retinal vasculitis in the moderately active phase of classical rheumatoid arthritis. Fluorescein angiography disclosed diffuse leakage from the retinal capillaries and cystoid macular edema, which subsided in response to oral ... | neoplasms |
Helicobacter pylori in dyspeptic patients in Kuwait. Two hundred and four patients, mainly Arabs, attending for upper gastrointestinal endoscopy at the gastroenterology clinic in Mubarak Al-Kabeer Hospital, Kuwait, were examined for evidence of infection with Helicobacter pylori and associated inflammation. Biopsy spec... | digestive system diseases |
Renal dysfunction after angiography; a risk factor analysis in patients with peripheral vascular disease. Angiography is required for a detailed anatomical investigation before reconstructive surgery or percutaneous transluminal angioplasty can be performed. Although angiography is a safe procedure, it is associated wi... | cardiovascular diseases |
Visual recovery in patients with optic neuritis and visual loss to no light perception. We reviewed the records of 151 patients with optic neuritis examined over an eight-year period. Of these patients, 12 developed visual acuity of no light perception during the first episode of optic neuritis in the affected eye. Eig... | general pathological conditions |
Use of gadolinium-enhanced magnetic resonance imaging in the diagnosis and management of posterior fossa hemangioblastomas. The diagnosis of central nervous system hemangioblastoma as well as the surgical treatment requires the accurate radiologic visualization of both the cystic and solid components of the tumor. We r... | neoplasms |
Job's syndrome: a rare cause of recurrent lung abscess in childhood. A clinical syndrome characterized by recurrent staphylococcal infection of the skin and respiratory tract from birth was described in 1966 and referred to as Job's syndrome. Marked hyperimmunoglobulinemia E was later found to be associated with this s... | general pathological conditions |
Inguinal hernia complicating flexible sigmoidoscopy. Flexible sigmoidoscopy has become part of routine preoperative workup for patients over the age of fifty who present with an inguinal hernia. A recent experience with two patients with a left inguinal hernia allowing sigmoid colon to herniate into the scrotum bring a... | digestive system diseases |
Neuropsychological profile linked to low dopamine: in Alzheimer's disease, major depression, and Parkinson's disease. A distinct pattern of neuropsychological deficits was associated with low homovanillic acid (HVA) in the cerebrospinal fluid of 21 patients with: Alzheimer's disease (9), Parkinson's disease (8) and maj... | nervous system diseases |
Use of the polymerase chain reaction to monitor the effectiveness of ex vivo tumor cell purging. The polymerase chain reaction (PCR) was used to detect residual malignant disease before and after ex vivo purging with monoclonal antibodies and complement or immunomagnetic treatment of BM samples contaminated with known ... | general pathological conditions |
The changing face of dermatology out-patient referrals in the south-east of Scotland. A study of out-patient dermatological services (NHS and private) in the south-east of Scotland was carried out by medical staff in the Department of Dermatology in Edinburgh during the month of November 1988. The aim was to assess cha... | neoplasms |
Adjunctive surgery after chemotherapy for nonseminomatous germ cell tumors: recommendations for patient selection. One hundred eighty-five patients who underwent surgery within 6 months of completing chemotherapy were identified from 360 patients with nonseminomatous germ cell tumors (NSGCT) treated with Memorial Hospi... | neoplasms |
Penetration of the pericardium by a gastric ulcer--survival after pericardiocentesis. Elderly patients often have unusual manifestations of common illnesses. We describe a geriatric patient having a pneumopericardium from pericardial penetration by a gastric ulcer. Benign gastric ulceration causing perforation of the p... | digestive system diseases |
A multicentre follow-up study of 1152 patients with myasthenia gravis in Italy. A multicentre retrospective study was carried out on the characteristics and course of myasthenia gravis (MG) in Italy. Data from 1152 patients, fairly representative of the myasthenic population seeking medical advice, were analysed for di... | nervous system diseases |
Expected gains in life expectancy from various coronary heart disease risk factor modifications BACKGROUND. Despite much evidence that modifying risk factors for coronary heart disease can decrease morbidity and mortality, little is known about the impact of risk-factor modification on life expectancy. METHODS AND RESU... | cardiovascular diseases |
A mutation in the gene for type III procollagen (COL3A1) in a family with aortic aneurysms. Experiments were carried out to test the hypothesis that familial aortic aneurysms, either thoracic or abdominal, are caused by mutations in the gene for type III procollagen (COL3A1) similar to mutations in the same gene that h... | cardiovascular diseases |
Primary central nervous system lymphoma in patients with and without the acquired immune deficiency syndrome. A retrospective analysis and review of the literature. Twenty-two cases of PCL were reviewed, in which 9 patients had AIDS and 13 did not. A review of the literature identified 247 cases of AIDS-related PCL. Di... | neoplasms |
Factitious cyclic hypersomnia: a new variant of factitious disorder. The central goal of patients with factitious disorders is to receive medical care. Unnecessary diagnostic procedures and recurrent hospitalizations often ensue. We saw a 39-year-old man with a novel variation of this disorder: factitious cyclic hypers... | general pathological conditions |
Reasons why mastectomy patients do not have breast reconstruction. Breast reconstruction after mastectomy is valuable, yet only a small percentage of eligible patients ever have reconstruction. Little has been done to determine why so few patients proceed with reconstructive surgery. A homogeneous population of mastect... | neoplasms |
Survival of children and adolescents with acute lymphoid leukemia. A study of American Indians and Hispanic and non-Hispanic whites treated in New Mexico (1969 to 1986). During the period 1969 to 1986, 196 American Indian and Hispanic and non-Hispanic white children and adolescents (ages, 0 to 19 years) were treated fo... | neoplasms |
Intraperitoneal lymphokine-activated killer-cell and interleukin-2 therapy for malignancies limited to the peritoneal cavity. Autologous lymphokine-activated killer (LAK) cells and recombinant human interleukin-2 (rIL-2) were administered intraperitoneally (IP) to 24 patients with malignancies limited to the peritoneal... | neoplasms |
Stress adaptation and low-frequency impedance of rat lungs. At transpulmonary pressures (Ptp) of 7-12 cmH2O, pressure-volume hysteresis of isolated cat lungs has been found to be 20-50% larger than predicted from their amount of stress adaptation (J. Hildebrandt, J. Appl. Physiol. 28: 365-372, 1970). This behavior is i... | general pathological conditions |
Treatment of moderate-to-severe hypothermia in an urban setting. STUDY OBJECTIVES: To study the treatment of moderate-to-severe hypothermia using a combination of core rewarming techniques. DESIGN: A prospective study. SETTING: The emergency department of an urban, community hospital. TYPE OF PATIENTS: Sixteen patients... | general pathological conditions |
The potential of 2-deoxy-2[18F]fluoro-D-glucose (FDG) for the detection of tumor involvement in lymph nodes. To assess the potential of FDG for PET imaging of nodal tumor metastases, we evaluated its uptake into normal lymph nodes, tumor-involved lymph nodes, and subcutaneous tumor xenografts in rodents. Normal lymph n... | neoplasms |
In vitro and in vivo testing of a new valved intravascular catheter design. Long-term intravascular catheterization carries a finite risk of catheter occlusion. A catheter tip valve design is presented (Buchwald-Wigness, Strato Medical Corporation, Beverly, MA) which incorporates features designed to decrease the risk ... | cardiovascular diseases |
Late results of 200 repeat coronary artery bypass operations. To determine the clinical outcome and the long-term results of a second coronary artery bypass operation, we studied preoperative clinical status and catheterization data in 200 consecutive patients over a 9-year period (1979 to 1987) (mean follow up time 34... | cardiovascular diseases |
Functional results of facial nerve suture after removal of acoustic neurinoma: analysis of 25 cases. The facial nerve is sometimes severed during the removal of acoustic neurinomas, either intentionally to ensure complete removal, or unintentionally because of difficulties in identification. In such cases we have, if p... | general pathological conditions |
MyoD induces growth arrest independent of differentiation in normal and transformed cells. MyoD is a gene involved in the control of muscle differentiation. We show that MyoD causes growth arrest when expressed in cell lines derived from tumors or transformed by different oncogenes. MyoD-induced growth inhibition was d... | general pathological conditions |
Prognosis and prognostic factors of retinal infarction: a prospective cohort study. OBJECTIVE--To determine the prognosis and adverse prognostic factors in patients with retinal infarction due to presumed atheromatous thromboembolism or cardiogenic embolism. DESIGN--Prospective cohort study. SETTING--University hospita... | general pathological conditions |
Complications associated with needle localization biopsy of the breast. A review of 144 consecutive needle localization biopsies of the breast (NLBB) was performed to assess complications associated with this procedure. Thirty-four complications occurred in 27 patients. There were 11 wound infections associated with NL... | neoplasms |
Pulmonary blastoma with malignant melanoma component. Pulmonary blastomas are rare primary tumors that consist of tubular or glandular structures embedded in an undifferentiated mesenchymal stroma. Focal cartilage, bone, and skeletal muscle as well as squamous differentiation have been described in these tumors. We rep... | neoplasms |
Mild ischemia predisposes the S3 segment to gentamicin toxicity. The purpose of these studies was to determine if a functionally insignificant ischemic insult, occurring prior to gentamicin administration, enhanced gentamicin nephrotoxicity. Bilateral renal pedicle clamp studies demonstrated that 15 minutes of ischemia... | cardiovascular diseases |
Rapid and correct diagnosis of myocardial infarction: standardized case history and clinical examination provide important information for correct referral to monitored beds. The value of thorough examination of the case history as a diagnostic tool on hospitalization of patients with suspected myocardial infarction wa... | cardiovascular diseases |
Immunohistochemical alterations in basement membrane components of squamous cell carcinoma. To investigate alterations in the basement membrane (BM) in squamous cell carcinoma (SCC), we investigated 20 tumors. Four had the cytologic characteristics of Bowen's disease (SCC-BD) and 16 did not have them (SCC-NB). Tumors w... | neoplasms |
Pathogenesis of ischemic necrosis in random-pattern skin flaps induced by long-term low-dose nicotine treatment in the rat. The objectives of the present experiments were to study the effects of long-term low-dose nicotine treatment on skin hemodynamics, viability, and microvascular morphology in 4 x 10 cm dorsally bas... | general pathological conditions |
Heart weights of white men 20 to 39 years of age. An analysis of 218 autopsy cases. Review of autopsy data for 218 white men between 20 and 39 years of age who died of injuries or suddenly and unexpectedly indicated a mean heart weight of 371 g. The mean for those dying of external causes was 364 g whereas the mean for... | general pathological conditions |
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