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Downslope claudication in eosinophilic fasciitis: a fourth type of claudication--case presentations. Two patients who presented with discomfort in the calves while walking down a slope were diagnosed as suffering from eosinophilic fasciitis of the lower limbs. Following therapy of the underlying disease, this peculiar ... | cardiovascular diseases |
Chronic diarrhea in essential mixed cryoglobulinemia: a manifestation of visceral vasculitis? Gastrointestinal involvement occurs frequently in essential mixed cryoglobulinemia, and most often involves the liver and spleen. Intestinal involvement is much less common and is generally felt to be a late and often catastro... | digestive system diseases |
Histologic pattern analysis of basal cell carcinoma. Study of a series of 1039 consecutive neoplasms. This study attempts to define histologic patterns in 1039 consecutive cases of basal cell carcinoma and to correlate these patterns with adequacy of margins of surgical excision. Five major histologic patterns were ide... | neoplasms |
Management of hypertension and cardiovascular risk. Blood pressure reduction in hypertensive patients is a surrogate for the real therapeutic goal of reducing the risks consequent to hypertension. This surrogate is convenient but its use may have important therapeutic implications. Results of treatment with new antihyp... | cardiovascular diseases |
Normalization of Doppler indices of diastolic dysfunction during pacing is a sign of ischemic mitral regurgitation. Twenty-three patients with angina who were undergoing diagnostic cardiac catheterization underwent cardiac pacing with simultaneous hemodynamic and Doppler echocardiographic evaluation to assess the effec... | cardiovascular diseases |
Acetylsalicylic acid vs. metoprolol in migraine prophylaxis--a double-blind cross-over study. In a double blind cross-over study, 28 patients, 5 male and 23 female, aged 31 +/- 14 years, after a run-in period of 8 weeks, were treated for 3 months with acetylsalicylic acid and for another 3 months with metoprolol, both ... | nervous system diseases |
Use of leukocyte-depleted platelet concentrates for the prevention of refractoriness and primary HLA alloimmunization: a prospective, randomized trial. Compared with conventional transfusion regimes a strong reduction in HLA alloimmunization and refractoriness to platelet transfusions is obtained when both red blood ce... | neoplasms |
Mapping of a functional autoimmune epitope on the beta 1-adrenergic receptor in patients with idiopathic dilated cardiomyopathy. The presence and properties of serum autoantibodies against beta-adrenergic receptors in patients with idiopathic dilated cardiomyopathy were studied using synthetic peptides derived from the... | cardiovascular diseases |
A phase I study of 4'-0-tetrahydropyranyladriamycin. Clinical pharmacology and pharmacokinetics. A Phase I study of intravenous (IV) bolus 4'-0-tetrahydropyranyladriamycin (Pirarubicin) was done in 55 patients in good performance status with refractory tumors. Twenty-six had minimal prior therapy (good risk), 23 had ex... | neoplasms |
Beneficial effect of atrial pacing in severe acute aortic regurgitation and role of M-mode echocardiography in determining the optimal pacing interval. The effect of atrial pacing on cardiac performance was assessed in 11 men (aged 20 to 64 years) with recent-onset severe aortic regurgitation (AR), all of whom had dias... | cardiovascular diseases |
Dreams and epilepsy. The relationship between dreams and epilepsy is illustrated by two patients whose awake epileptic seizures and recurrent dreams during night sleep had similar content. In both of our cases the EEG showed right anterior temporal spike discharge, suggesting a role for the temporal lobe in the associa... | nervous system diseases |
Lithiumogenic disorders of the thyroid and parathyroid glands as surgical disease. Little notice has been paid in the surgical literature to problems with psychoeffective lithium, which by interfering with adenylate cyclase affects thyroid and parathyroid function, causing hypercalcemia, hyperparathyroidism, and hypoth... | neoplasms |
Fulminant pseudomonal keratitis and scleritis in human immunodeficiency virus-infected patients. Patients with human immunodeficiency virus infection are predisposed to fungal, parasitic, and viral infections. Bacterial infection can also be seen, although ocular bacterial infections have not been reported in patients ... | general pathological conditions |
Study of the influence of left bundle branch block on the signal-averaged electrocardiogram: a qualitative and quantitative analysis. To study the influence of left bundle branch block (LBBB) on the signal-averaged electrocardiogram (SAECG), quantitative and qualitative analyses of SAECG parameters were undertaken in 4... | general pathological conditions |
Polypoid melanoma: a virulent variant of nodular melanoma. Report of three cases and literature review. We report the cases of three patients with polypoid melanoma. In no case was there microscopic evidence of melanoma cell invasion below the papillary dermis. In the polypoid variant of nodular melanoma, melanoma cell... | neoplasms |
Esophageal malignancies: is preoperative radiotherapy the way to go? During the period 1969 to 1988, 68 patients with esophageal malignancy were subjected to preoperative radiotherapy consisting of 30 Gy over 3 weeks followed by esophagectomy after a wait of 2 weeks. Sixty-two of 68 patients (91%) were followed up retr... | neoplasms |
The starved colon--diminished mucosal nutrition, diminished absorption, and colitis. Nutrition of colonic epithelial cells is mainly from short chain fatty acids (SCFAs) produced by bacterial fermentation in the colonic lumen. n-Butyrate contributes more carbon of oxidation to epithelial cells than glucose or glutamine... | digestive system diseases |
Biliobiliary fistula: preoperative diagnosis and management implications. Experience with cholecystohepaticodochal and cholecystocholedochal fistulas as a result of an erosion of gallstones from the gallbladder into the adjacent common duct in five patients is presented. The incidence was 1.4% in a population of 350 pa... | digestive system diseases |
Prevalence of human immunodeficiency virus seropositivity in pediatric emergency room patients undergoing phlebotomy. Information on the prevalence of human immunodeficiency virus (HIV) infection among children and adolescents requiring medical care is sparse. A small but significant risk of seroconversion occurs in he... | general pathological conditions |
Acute myocardial infarction resulting from the migration of a Greenfield filter. A paraplegic patient who underwent the placement of Greenfield filters to prevent pulmonary emboli had one of the filters migrate proximally to the junction of the inferior vena cava and right atrium, then into the right atrium a few month... | cardiovascular diseases |
Successful treatment of pancreatic pseudocyst with a somatostatin analogue and catheter drainage. We report a patient with bile duct stone-induced pancreatitis who subsequently developed a large pseudocyst that became infected after endoscopic retrograde cholangiopancreatography (ERCP) was done for extraction of the st... | digestive system diseases |
Antibodies in anti-HBe-positive patient sera bind to an HBe protein expressed on the cell surface of human hepatoma cells: implications for virus clearance. The relevance of the recently described membrane-bound form of the HBe protein for the antiviral immune response was examined. The data show that antibodies in ant... | neoplasms |
Mycosis fungoides-like lesions associated with phenytoin and carbamazepine therapy. We report the cases of four patients who were taking the anticonvulsant drugs phenytoin or carbamazepine and in whom skin lesions developed that showed histologic features suggestive of mycosis fungoides. Two patients had a solitary les... | nervous system diseases |
Two different point G to A mutations in exon 10 of the porphobilinogen deaminase gene are responsible for acute intermittent porphyria. Two mutations of the porphobilinogen (PBG) deaminase gene resulting in cross-reacting immunological material (CRIM) positive forms of acute intermittent porphyria (AIP) have been ident... | general pathological conditions |
Hybridization protection assay: a rapid, sensitive, and specific method for detection of Philadelphia chromosome-positive leukemias. The Philadelphia (Ph1) chromosome is present in greater than 90% of patients with chronic myelogenous leukemia (CML) and in 2% to 20% of those with acute leukemias, for which it is an imp... | general pathological conditions |
Observer reliability in detecting surreptitious random occlusions of the monaural esophageal stethoscope. The esophageal stethoscope is used often during anesthesia to monitor ventilation and cardiac function. Deficiencies in observer vigilance may limit the effectiveness of this monitoring instrument. The aim of this ... | general pathological conditions |
Central nervous system involvement in Von Hippel-Lindau disease. Fifty individuals with Von Hippel-Lindau disease (VHL) were studied with gadolinium-enhanced magnetic resonance imaging (MRI) to determine the frequency and distribution of CNS lesions. The associated clinical features were also reviewed. Thirty-six (72%)... | nervous system diseases |
The scimitar syndrome. The clinical spectrum of the scimitar syndrome ranges from severely ill infants to asymptomatic adults. The true incidence of the disorder is unknown because the syndrome may remain undetected in asymptomatic patients until a chest roentgenogram is obtained. We have presented the contrasting clin... | general pathological conditions |
Involvement of thromboxane and neutrophils in multiple-system organ edema with interleukin-2. Interleukin-2 (IL-2) produces toxicity characterized by generalized edema within 24 hours. This study tests whether the rate of IL-2 administration modulates the onset of edema and examines thromboxane (Tx) and neutrophils as ... | general pathological conditions |
Demonstration of an area of slow conduction in human atrial flutter. Ten patients with chronic atrial flutter were studied prospectively using electrophysiologic mapping and pacing techniques to assess the mechanism of atrial flutter and the presence of an area of slow conduction in the atria. Electrograms recorded fro... | general pathological conditions |
Infection during chronic epidural catheterization: diagnosis and treatment. A potentially serious complication of long-term epidural catheterization in cancer patients is infection. The early signs of infection were studied in 350 patients in whom long-term epidural catheters were inserted. Three areas of the catheter ... | nervous system diseases |
Endoscopic laser surgery. A single-center comprehensive experience. A retrospective review of endoscopic procedures using the Nd:YAG laser was carried out for patients treated between October 1985 and March 1989. During this 42-month period 165 procedures were performed on 100 patients. The study encompasses a unique p... | cardiovascular diseases |
Are cystgastrostomy and cystjejunostomy equivalent operations for pancreatic pseudocysts? To compare the effectiveness of cystgastrostomy and cystjejunostomy for treatment of pancreatic pseudocysts, 39 patients with cystgastrostomy were compared to 59 patients with cystjejunostomy. The groups were comparable in age, se... | digestive system diseases |
Biology and clinical significance of cytogenetic abnormalities in childhood acute lymphoblastic leukemia. Virtually all cases of childhood ALL have chromosomal abnormalities and half contain translocations, which are nearly equally divided between random and nonrandom rearrangements. Nonrandom chromosomal abnormalities... | general pathological conditions |
The emergence of hepatitis B as a sexually transmitted disease. In the United States, approximately 300,000 cases of hepatitis B virus infection occur annually, and heterosexual activity is one of the most commonly reported risk factors for acquiring disease. Until the number of infections transmitted through heterosex... | digestive system diseases |
Ischemia and reperfusion during intermittent coronary occlusion in man. Studies of electrocardiographic changes and CPK release. The course of 357 balloon inflations performed during 38 angioplasties for single-vessel coronary artery disease was prospectively studied using continuous ECG recording. Ischemic ECG changes... | cardiovascular diseases |
Tarsal tunnel syndrome. Causes and results of operative treatment. From 1975 to 1988, operative treatment was performed on 50 feet in 45 patients with tarsal tunnel syndrome. The causes of this syndrome were correlated with operative findings and included ganglia in 18, and a bony prominence from talocalcaneal coalitio... | nervous system diseases |
Treatment of recurrent ischemia after thrombolysis and successful reperfusion for acute myocardial infarction: effect on in-hospital mortality and left ventricular function. To determine the effect of treatment of recurrent ischemia after reperfusion for acute myocardial infarction on in-hospital mortality and left ven... | cardiovascular diseases |
Sensitivity of exercise electrocardiography for acute cardiac events during moderate and strenuous physical activity. The Lipid Research Clinics Coronary Primary Prevention Trial. We determined whether the exercise electrocardiogram predicted acute cardiac events during moderate or strenuous physical activity among 361... | cardiovascular diseases |
Neuro-imaging and positron emission tomography of congenital homonymous hemianopsia. Congenital homonymous hemianopsia is an uncommon asymptomatic visual field defect discovered typically in young adult life that is caused by a diverse group of insults to the retrochiasmal afferent visual system occurring prenatally, a... | general pathological conditions |
Thyroglobulin level as a predictive factor of tumoral recurrence in differentiated thyroid cancer. Ninety-eight patients with differentiated thyroid carcinoma were studied. Actuarial methods were used to investigate the 10-yr probability of survival (pS) and disease-free survival (pDFS). Our results show that the pDFS ... | neoplasms |
Differential effects of continuous versus intermittent suction on tracheal tissue. The purpose of this study was to determine the differential effect of continuous versus intermittent application of negative pressure on tracheal tissue during endotracheal suctioning. The sample consisted of 12 mongrel dogs, randomly as... | general pathological conditions |
Follicular thyroid cancer treated at the Mayo Clinic, 1946 through 1970: initial manifestations, pathologic findings, therapy, and outcome We retrospectively analyzed the outcome of all patients who received their primary treatment for follicular thyroid cancer at the Mayo Clinic between 1946 and 1970. The diagnosis wa... | general pathological conditions |
Angiosarcoma of the uterus: a case report. We are reporting a case of angiosarcoma of the uterus in which the diagnosis was confirmed ultrastructurally by demonstration of Weibel-Palade bodies in the tumor cells. Only 10 cases of this entity have been previously documented in the literature. | neoplasms |
Lewis system alterations in gastric carcinogenesis. Alterations in the expression of type 1 blood group-related antigens (Lewis a and b) were examined immunohistochemically in 371 consecutives gastric biopsy and 80 surgical specimens from patients of gastric carcinoma. The ABH and Lewis phenotype and secretor status of... | neoplasms |
Reentrant ventricular arrhythmias in the late myocardial infarction period: mechanism by which a short-long-short cardiac sequence facilitates the induction of reentry. The electrophysiological mechanism by which a short-long-short stimulated cardiac sequence facilitates the induction of ventricular tachyarrhythmia was... | cardiovascular diseases |
Intussusception encephalopathy: an underrecognized cause of coma in children. Intestinal intussusception is a common cause of bowel obstruction in infancy and early childhood. Typically the presenting signs and symptoms are referable to the abdomen. On occasion the most prominent presenting feature is depressed level o... | general pathological conditions |
Sinus arrest induced by trivial nasal stimulation during alfentanil-nitrous oxide anaesthesia. A case is reported of bradycardia and sinus arrest induced by insertion of a nasal temperature probe. Other possible causes of bradycardia and sinus arrest under anaesthesia are reviewed briefly. Evidence for the neurological... | cardiovascular diseases |
Left ventricular versus left atrial cannulation for the Thoratec ventricular assist device. In a retrospective study of 28 patients (23 men, 5 women) supported with ventricular assist devices greater than 3 days, the effect of LV cannulation versus LA cannulation on device performance was compared. Patients ranged in a... | cardiovascular diseases |
Indwelling epidural catheters for pain control in gynecologic cancer patients. Seven patients with severe pain caused by an advanced, incurable gynecologic malignancy were treated with an indwelling epidural catheter connected to an implantable subcutaneous port through which morphine was infused. There were few major ... | neoplasms |
Effects of specific mu and kappa opiate tolerance and abstinence on hypothalamo-pituitary-adrenal axis secretion in the rat. Chronic administration of opiates to rats results in HPA axis tolerance and abstinence-induced hypersecretion. The effects of specific mu and kappa tolerance and withdrawal on the functional secr... | general pathological conditions |
A single case of Huntington's disease simultaneously occurring with obstructive hydrocephalus. A case of simultaneously occurring Huntington's disease and obstructive hydrocephalus is presented. Huntington's and other neurodegenerative diseases have been described with normal-pressure hydrocephalus; however, no such de... | nervous system diseases |
Selective impairment of memory and visual perception in splenial tumours. The neuropsychological abnormalities found in 9 patients with tumours involving the splenium of the corpus callosum are described. The outstanding features of their cognitive deficits were a severe memory deficit and visual perception impairment ... | neoplasms |
Plasma exchange in chronic progressive multiple sclerosis: a long-term study. Plasma exchange (PE) was shown in a previous double-blind randomized controlled study to confer significant additional benefit at 1 year upon patients with chronic progressive multiple sclerosis (CPMS) treated with immunosuppressive drug ther... | general pathological conditions |
Obstructive sleep apnea presenting with nocturnal angina, heart failure, and near-miss sudden death. An obese woman with a one-year history of episodic nocturnal chest pain was admitted because of shock and pulmonary edema. A clinical diagnosis of acute myocardial infarction and cardiogenic shock was made. She was vent... | nervous system diseases |
Appendiceal carcinoma masquerading as primary bladder carcinoma. We report 2 cases of appendiceal adenocarcinoma invading the bladder. Both tumors masqueraded as primary bladder carcinomas. Cystoscopic biopsies obtained adenocarcinomatous tissue and the secondary nature of the bladder lesion became apparent at laparoto... | digestive system diseases |
Functional upper airway obstruction in adolescents. Functional upper airway obstruction is an uncommon manifestation of a conversive reaction characterized by recurrent stridor attacks caused by adduction of the vocal cords during inspiration. The oxygen saturation never drops to pathologic levels. The stridor is not a... | general pathological conditions |
Clinical, radiographic, and pathological features of symptomatic Rathke's cleft cysts. The clinical, radiographic, and pathological findings in 155 patients with symptomatic Rathke's cleft cysts are discussed. Eight patients were treated by the authors and 147 were collected in a review of the literature. This lesion o... | nervous system diseases |
Trends in female breast cancer in Connecticut and the United States. Trends for female breast cancer were examined by age, period and cohort for the years 1950-1984 in U.S. mortality. Connecticut mortality and Connecticut incidence. Birth cohort patterns were evident for all three sets of data. The results confirm a co... | neoplasms |
Interleukin-5 is a human basophilopoietin: induction of histamine content and basophilic differentiation of HL-60 cells and of peripheral blood basophil-eosinophil progenitors. Cytokine-induced differentiation of basophils may contribute to various inflammatory processes. We examined the effects of recombinant human in... | neoplasms |
Histopathologic grading of salivary gland neoplasms: II. Acinic cell carcinomas. Acinic cell carcinomas display varied cytoarchitectural patterns of growth that should allow for formulation of histopathologic grading. Grading of these carcinomas may serve to identify subsets whose biologic behavior is more aggressive t... | neoplasms |
Clinical results of femoropopliteal bypass using externally supported (EXS) Dacron grafts: with a comparison of above- and below-knee anastomosis. As of the end of September 1989, 52 EXS Dacron grafts had been implanted for femoropopliteal bypass operations. The distal ends of 27 grafts were anastomosed to above-knee p... | cardiovascular diseases |
OKT3 encephalopathy. OKT3 therapy for induction immunosuppression in a patient who underwent renal transplantation produced obtundation and quadriparesis associated with computed tomographic scan evidence of brain edema. These findings resolved over 3 days with supportive therapy and OKT3 withdrawal. | nervous system diseases |
Characteristics of erythroleukemia cells selected for vincristine resistance that have accelerated inducer-mediated differentiation. The induction of murine erythroleukemia cells (MELC; DS19/Sc9) to terminal differentiation by hexamethylenebisacetamide (HMBA) is characterized by a latent period of 10-12 hr before onset... | neoplasms |
Nitrite from inflammatory cells--a cancer risk factor in ulcerative colitis? Elevated levels of luminal nitrite and a lowered luminal pH were found in 77 percent of patients with acute ulcerative colitis. No luminal nitrite was found in healthy control subjects. Nitrites are a secretory product of activated macrophages... | neoplasms |
Pneumococcal peritonitis complicating CAPD--was the indwelling intrauterine device to blame? A 45-year-old woman on CAPD developed pneumococcal peritonitis. This is the second such case of Streptococcus pneumoniae peritonitis complicating CAPD. The role of an indwelling intrauterine device (IUD) in producing ascending ... | digestive system diseases |
Pathogenetic role of Helicobacter pylori in duodenal ulcer disease. Multivariate analysis of factors affecting relapse. The pathogenesis of duodenal ulcer disease is multifactorial and the contribution of Helicobacter pylori in relation to the other factors to the release of duodenal ulcer is unknown. To investigate th... | digestive system diseases |
Acute myocarditis simulating myocardial infarction in a child. Pediatric chest pain usually occurs in benign conditions. However, this case portrays the dramatic electrocardiographic appearance of acute myocardial ischemia in a boy with biopsy-proven myocarditis who had only mild chest pain. This underscores the need f... | cardiovascular diseases |
The risk for systemic vascular diseases and mortality in patients with central retinal vein occlusion. In this cross-sectional study, the authors evaluated 197 patients diagnosed with central retinal vein occlusion (CRVO) at the Wilmer Ophthalmological Institute between 1980 and 1985 to determine the risk of systemic d... | cardiovascular diseases |
The abdominal trauma index--a critical reassessment and validation. The Abdominal Trauma Index (ATI) was devised to quantify the risk of complications following abdominal trauma. With scores greater than 25, the risk of postoperative complications became exponential. The purpose of the present study was to determine if... | general pathological conditions |
Phenobarbital and cerebral blood flow during hypertension in the newborn beagle. Phenobarbital sodium has been used in anticonvulsant concentrations (15 to 40 micrograms/mL serum) in premature newborns in attempts to prevent periventricular and intraventricular hemorrhages. Although its clinical usefulness in this rega... | general pathological conditions |
Five-year postoperative results of cemented femoral arthroplasty in patients with systemic bone disease. To determine whether bone cellular abnormality affects the results of cemented femoral arthroplasty, 21 patients had biopsies of the iliac crest and femoral cortex at the time of surgery. Roentgenographic and histom... | general pathological conditions |
Adenoidectomy in otitis media. A review. For many years adenoids were thought to affect adversely middle ear (ME) aeration by obstructing the eustachian tube opening, leading to ME infections and effusions. Consequently, the adenoids have often been removed in children suffering from ME diseases; indeed, adenoidectomy ... | general pathological conditions |
Antiplatelet drugs in femoropopliteal vein bypasses: a multicenter trial. To evaluate the influence of antiplatelet drugs on patency in femoropopliteal vein bypasses, 48 vascular surgeons recruited 549 patients to a randomized double-blind trial of aspirin (300 mg) + dipyridamole (150 mg) or placebo twice daily startin... | general pathological conditions |
Germfree animals and technics in surgical research. Germfree animals have been reared to a size, weight, and age permitting the performance of major surgical procedures and the pursuit of a variety of surgical research problems. Germfree dogs have been maintained in the isolator system through three generations, indica... | digestive system diseases |
Tuberothalamic infarct after division of a hypoplastic posterior communicating artery for clipping of a basilar tip aneurysm: case report. The authors present a case of a tuberothalamic infarct subsequent to division of the posterior communicating artery for clipping of a high-lying aneurysm of the basilar bifurcation ... | general pathological conditions |
Intradural epithelial cyst at the craniovertebral junction. Case report. A case of an intradural epithelial cyst at the craniovertebral junction is reported in a 37-year-old man. The classification of these rare lesions is discussed. | nervous system diseases |
Musculoskeletal problems in association with cloacal exstrophy. The records of all thirteen patients for whom a diagnosis of cloacal exstrophy had been recorded in our hospitals were analyzed for evidence of musculoskeletal problems. All thirteen patients had spina bifida, four had congenital scoliosis, two had congeni... | nervous system diseases |
Maternal outcome after open fetal surgery. A review of the first 17 human cases. A few fetal diseases may benefit from surgical treatment before birth, but hysterotomy and subsequent delivery by cesarean section pose a risk to the otherwise unaffected mother. To assess maternal risk of mortality, morbidity, and reprodu... | digestive system diseases |
Gastrointestinal disease and oral contraception. Oral contraceptive steroids play a major role in modern family planning. With the present tendency to decrease the doses of both estrogens and progestogens, any factor that reduces the bioavailability of the lower-dose preparations may have an impact on contraceptive pro... | general pathological conditions |
Oral contraception in disease states. Oral contraceptives are clearly contraindicated in patients with a history of thromboembolic disease, ischemic heart attack, or cerebral stroke. Patients requiring long-term anticoagulant treatment can be treated with gonadotropin-releasing hormone analogs to prevent ovulation, bec... | cardiovascular diseases |
Effects of neuro-developmental treatment and orthoses on knee flexion during gait: a single-subject design. The interactive effects of neuro-developmental treatment and inhibitive ankle-height orthoses on gait were examined via a single-subject research design. Knee flexion during gait at initial contact, mid-stance, h... | nervous system diseases |
Influence of low osmolality contrast media on electrophysiology and hemodynamics in coronary angiography: differences between an ionic (ioxaglate) and a nonionic (iohexol) agent. It has recently been suggested that the addition of sodium to low osmolality contrast media may reduce the incidence of ventricular fibrillat... | cardiovascular diseases |
Vasculitis as a paraneoplastic syndrome. Report of 11 cases and review of the literature. In a study of 222 patients with vasculitis, we identified 11 who had an associated neoplasia. Seven had hematological neoplasia and 4 had solid malignant tumors. In 4 patients vasculitis gave the first evidence of the neoplasia or... | neoplasms |
Attitudes of major employers toward the employment of people with epilepsy: a 30-year study. Beginning in 1956, major San Francisco Bay area employers were sampled at 10-year intervals for a 30-year period to assess attitudes toward the employment of epileptic workers. In this time, we documented a trend of sustained p... | nervous system diseases |
Baffle fenestration with subsequent transcatheter closure. Modification of the Fontan operation for patients at increased risk Ventricular dysfunction, elevated pulmonary vascular resistance, and residual distal pulmonary artery distortion contribute to early mortality after a Fontan operation; they may be transient or... | general pathological conditions |
Abnormalities of von Willebrand factor multimers in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome. PURPOSE: To analyze and review von Willebrand factor (vWF) multimeric patterns in patients with single-episode thrombotic thrombocytopenic purpura (TTP), intermittent TTP (episodes at infrequent, i... | general pathological conditions |
Laryngeal dystonia: a series with botulinum toxin therapy. Laryngeal dystonia is a syndrome characterized by action-induced, involuntary spasms of the laryngeal muscles. Most patients have involvement of the adductor laryngeal muscles producing uncontrolled spasms during phonation, and a "strain-strangle" speech patter... | general pathological conditions |
Host response to mycobacterial infection in the alcoholic rat. Animals, chronically treated with alcohol, were inoculated with mycobacteria (bacillus Calmette-Guerin, 10.2 x 10(6) organisms) into the spleen to produce a granulomatous hepatitis. Before infection, chronic alcohol ingestion was associated with a depressed... | digestive system diseases |
Usefulness of antithrombotic therapy in resting angina pectoris or non-Q-wave myocardial infarction in preventing death and myocardial infarction (a pilot study from the Antithrombotic Therapy in Acute Coronary Syndromes Study Group). In a prospective pilot trial of antithrombotic therapy in the acute coronary syndrome... | general pathological conditions |
Increase in incidence of disease due to diagnostic drift: primary liver cancer in Denmark, 1943-85. OBJECTIVE--To examine the extent to which changes in diagnostic methods and classification are responsible for the striking increase in incidence of primary liver cancer in Denmark since 1943. DESIGN--Analysis of the tim... | neoplasms |
Asymmetric growth of the lateral cerebral ventricle in infants with posthemorrhagic ventricular dilation. Lateral cerebral ventricular volume in 36 preterm infants with or without an intraventricular hemorrhage, and with or without posthemorrhagic hydrocephalus, was measured longitudinally and compared with the ventric... | nervous system diseases |
Reconstructions after resections of tumors involving the proximal femur. Advances in prosthesis design, the use of allografts, and a systematic approach to the staging and surgical treatment of musculoskeletal tumors have made limb salvage possible in the proximal femoral region. With the use of effective adjuvant ther... | general pathological conditions |
Bilateral malignant phyllodes tumours. We report a rare example of bilateral primary malignant phyllodes tumours. The diagnosis was supported by the identification of a benign epithelial element in each lesion. The case illustrates the typical dimorphic features of malignant phyllodes tumours. A contralateral tumour sh... | neoplasms |
Flow cytometric DNA analysis of hepatocellular carcinoma: preliminary report. Flow cytometric DNA analysis was performed in 50 paraffin-embedded specimens of clinical hepatocellular carcinoma (HCC) after hepatic resections. The DNA distribution pattern was classified in two types, diploid and aneuploid, according to th... | neoplasms |
Effect of somatostatin analogue (octreotide) on blood flow to endocrine tumors metastatic to the liver: angiographic evaluation. The effect of an octapeptide analogue of somatostatin, octreotide, on tumor blood flow was evaluated with angiography in eight patients with hepatic endocrine tumors; one patient had primary ... | neoplasms |
Familial predisposition for herniation of a lumbar disc in patients who are less than twenty-one years old. The parents of sixty-three patients who were less than twenty-one years old and who had operatively confirmed herniation of a lumbar disc were interviewed regarding a history of sever back pain, sciatica, and her... | general pathological conditions |
Glucose-induced exertional fatigue in muscle phosphofructokinase deficiency BACKGROUND. The exercise capacity of patients with muscle phosphofructokinase deficiency is low and fluctuates from day to day. The basis of this variable exercise tolerance is unknown, but our patients with this disorder report that fatigue of... | general pathological conditions |
Liver transplantation: MR angiography with surgical validation. Thirty patients (mean age, 45 years) were evaluated with magnetic resonance (MR) angiography before liver transplantation to assess the accuracy of MR angiography. A series of breath-hold, two-dimensional images were acquired and subsequently processed to ... | cardiovascular diseases |
Isolated muscular sarcoidosis causing fever of unknown origin: the value of gallium-67 imaging. An unusual case of a patient with a long-standing fever of unknown origin (FUO) is presented whose gallium-67 (67Ga) images revealed increased activity only in the calf muscles bilaterally. Other imaging modalities also fail... | general pathological conditions |
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