text stringlengths 170 4k | label stringclasses 5
values |
|---|---|
Prevalence of unsuspected mitral regurgitation and left ventricular diastolic dysfunction in patients with coronary artery disease and acute pulmonary edema associated with normal or depressed left ventricular systolic function. To define the prevalence and role of left ventricular (LV) systolic dysfunction, LV diastol... | cardiovascular diseases |
Repeat operation for failure of antireflux procedures. The majority of patients who receive modern antireflux operations obtain substantial long-term relief of their symptoms. About 10% to 15% will have persistent or recurrent problems, some severe enough to warrant reoperation for correction. With careful symptom revi... | digestive system diseases |
Localization and peptide content of endocrine pancreatic tumors. Endocrine pancreatic tumors contain and frequently secret neurohormonal peptides. This phenomenon can be used as a diagnostic and classifying tool. This study analyzes 31 patients operated on because of an endocrine pancreatic tumor, including the diagnos... | neoplasms |
Itraconazole in the management of chronic dermatophytosis. Fifty-five patients with griseofulvin-unresponsive dermatophytosis caused by Trichophyton rubrum were treated with itraconazole. They had either tinea corporis or "dry type" infections of the palms, soles, or nails. The following sites were affected: trunk (12 ... | general pathological conditions |
Effect of severe pulmonary hypertension on the calculation of mitral valve area in patients with mitral stenosis. We studied 50 consecutive patients with mitral valve stenosis (MS) by cardiac catheterization and Doppler echocardiography to assess whether the presence of severe pulmonary hypertension affected the calcul... | general pathological conditions |
Neodymium:YAG laser treatment of bladder hemangiomas. We present 3 cases of bladder hemangiomas, one single and two multiple, with a long-term history of recurrent hematuria, treated with endoscopic neodymium:YAG (yttrium, aluminum, garnet) laser photocoagulation, and obtaining good results. | neoplasms |
Prostaglandin F1 alpha levels during and after neonatal extracorporeal membrane oxygenation. Infants receiving extracorporeal membrane oxygenation therapy undergo long-term cardiopulmonary bypass, are systemically heparinized, and frequently receive platelet transfusions. Prostacyclin is a powerful inhibitor of platele... | general pathological conditions |
Controlled trial of antimycobacterial therapy in Crohn's disease. Clofazimine versus placebo. In order to study the effect of clofazimine, a powerful antimycobacterial and antiinflammatory agent, 49 patients with active Crohn's disease were randomized to either corticosteroids plus clofazimine 100 mg daily (N = 25) or ... | digestive system diseases |
Persistent segmental cutaneous anesthesia after a brown recluse spider bite. Patients with brown recluse spider bites commonly suffer from pain, muscular aching, and a variety of local dysesthesias during the acute and resolution phases of toxin-induced injury. This is our first well-documented observation of persisten... | general pathological conditions |
Experimental contrast-associated nephropathy and its clinical implications. Acute renal failure after contrast media injection has been recognized for at least 35 years but the exact mechanism responsible for the renal injury remains an enigma. The clinical characteristics of contrast-induced nephropathy (CAN) are well... | cardiovascular diseases |
Segmental vascular resistance in postobstructive pulmonary vasculopathy. Chronic unilateral pulmonary arterial ligation has been touted as a model of arteriopathy resulting in a tremendous increase in anastomotic bronchial flow (Qbr) via collaterals. To investigate its effects on the pulmonary vasculature, we ligated t... | cardiovascular diseases |
Meningiomas involving the clivus: a six-year experience with 41 patients. A series of 41 meningiomas involving the clivus operated on from July 1983 to January 1990 is reported. The presenting symptoms and signs of these patients were similar to those reported previously. All the patients were evaluated by pre- and pos... | nervous system diseases |
IgD immune complex vasculitis in a patient with hyperimmunoglobulinemia D and periodic fever. We describe a 27-year-old Dutch woman with the hyperimmunoglobulinemia D and periodic fever syndrome. During febrile attacks she occasionally presented with skin lesions on the distal parts of her upper and lower extremities, ... | general pathological conditions |
Recovery profile after desflurane-nitrous oxide versus isoflurane-nitrous oxide in outpatients. Thirty-eight healthy outpatients undergoing elective surgical procedures lasting 1-3 h were randomly assigned to receive either desflurane 3% (approximately 0.5 MAC) or isoflurane 0.6% (approximately 0.5 MAC) for maintenance... | nervous system diseases |
Radioimmunoscintigraphy using iodine-131-anti-CEA monoclonal antibodies and thallium-201 scintigraphy in medullary thyroid carcinoma: a case report. This case report demonstrates the use of thallium-201 (201Tl) scans versus iodine-131- (131l) anti-CEA F(ab')2 scans in a patient with high serum CEA levels due to metasta... | neoplasms |
Comparison of pre- and postoperative conduction patterns in patients surgically cured of atrioventricular node reentrant tachycardia. Patients with atrioventricular (AV) node reentrant tachycardia characteristically have short and constant retrograde His-atrium conduction times (H2A2 intervals) during the introduction ... | cardiovascular diseases |
Mechanical ventilation in medical and neurological diseases: 11 years of experience. Mechanical ventilation (MV) is imperative in many forms of acute respiratory failure (ARF). The aim of this work was to review all episodes of MV in a Medical Intensive Care Unit (MICU) during the 11-year period 1976-1986. Four per cen... | nervous system diseases |
A manifesting carrier of Duchenne muscular dystrophy with severe myocardial symptoms. A 42-year-old so-called manifesting carrier of Duchenne muscular dystrophy (DMD), whose first complaints were severe myocardial symptoms, is described. Immunohistochemical study using anti-dystrophin anti-serum and analysis of cloned ... | cardiovascular diseases |
Influence of right bundle branch block on short- and long-term survival after acute anterior myocardial infarction The impact of right bundle branch block on long-term prognosis after anterior wall myocardial infarction is unclear. In 932 patients with Q wave anterior infarction, the short- and long-term prognostic sig... | cardiovascular diseases |
Local control of auricular, periauricular, and external canal cutaneous malignancies with Mohs surgery. Three hundred ninety-seven patients with 407 cutaneous malignancies of the auricle, periauricular region, and cartilaginous external ear canal were reviewed. Tumors were most commonly located in the preauricular and ... | neoplasms |
Clinical features of misdiagnosed appendicitis in children. STUDY OBJECTIVE: To compare clinical features of children with misdiagnosed appendicitis with those of children with appendicitis initially diagnosed correctly. DESIGN: Retrospective review of hospital, emergency department, and clinic records. SETTING: Univer... | digestive system diseases |
Topical silicone gel for the prevention and treatment of hypertrophic scar. We studied the effects of a silicone gel bandage that was worn for at least 12 hours daily on the resolution of hypertrophic burn scar. In a second cohort, the prevention of hypertrophic scar formation in fresh surgical incisions by this bandag... | general pathological conditions |
Spontaneous rupture of liver during pregnancy: current therapy. Spontaneous hepatic rupture secondary to severe pregnancy-induced hypertension is associated with a high rate of maternal and fetal mortality. Numerous types of surgical management have been described, but a uniform surgical approach has not been accepted.... | cardiovascular diseases |
Bacteremia in an ambulatory setting. Improved outcome in children treated with antibiotics. We undertook a study of 414 bacteremic patients (167 with Haemophilus influenzae and 247 with Streptococcus pneumoniae bacteremia) to evaluate their clinical presentation, laboratory and clinical results, and subsequent outcomes... | nervous system diseases |
Cystic tumors of the pancreas. New clinical, radiologic, and pathologic observations in 67 patients. Within a 12-year period we treated 67 patients (49 women, 18 men; mean age, 61 years) with cystic neoplasms of the pancreas, including 18 serous cystic adenomas, 15 benign mucinous cystic neoplasms, 27 mucinous cystaden... | digestive system diseases |
The effect of continuous drainage of cerebrospinal fluid in patients with subarachnoid hemorrhage: a retrospective analysis of 108 patients. The effects of continuous drainage of cerebrospinal fluid (CSF) on vasospasm and hydrocephalus were analyzed retrospectively in 108 patients with subarachnoid hemorrhage (SAH) who... | cardiovascular diseases |
Histologic abnormalities of large and small coronary arteries, neural structures, and the conduction system of the heart found in postmortem studies of individuals dying from the toxic oil syndrome. Hundreds died and thousands were poisoned by rapeseed oil adulterated with aniline and sold illegally in Spain in 1981. T... | cardiovascular diseases |
Thyroid disease and pregnancy. Thyroid disease is common in younger women and may be a factor in reproductive dysfunction. This probably only applies to severe cases of hyper- or hypothyroidism. Once adequately treated, neither of these disorders significantly impacts on fertility. The key is to recognize and to treat ... | neoplasms |
Eosinophilic fasciitis associated with tryptophan ingestion. A manifestation of eosinophilia-myalgia syndrome. Recently, the ingestion of tryptophan has been associated with eosinophilia-myalgia syndrome, which is characterized by eosinophilia, myalgias, and several less consistently reported findings. We treated 13 pa... | general pathological conditions |
Coronary angioplasty of anomalous coronary arteries: notes on technical aspects. Five patients with significant atherosclerotic lesions of anomalous coronary arteries underwent coronary angioplasty of the anomalous vessel. Four patients had anomalous circumflex artery and 1 had an anomalous right coronary artery. Angio... | cardiovascular diseases |
Late juvenile-onset Krabbe's disease. Krabbe's disease is an autosomal recessive leukodystrophy characterized by a lack of galactocerebroside beta-galactosidase activity. In contrast to the classic early infantile-onset form of Krabbe's disease, less recognized, late-onset variants exist. The authors present a case of ... | nervous system diseases |
Differential histopathology of primary atherosclerotic and restenotic lesions in coronary arteries and saphenous vein bypass grafts: analysis of tissue obtained from 73 patients by directional atherectomy. Vascular tissue obtained using a directional percutaneous atherectomy device was examined microscopically. Tissue ... | cardiovascular diseases |
Similar time course of ST depression during and after exercise in patients with coronary artery disease and syndrome X. To assess whether the time course of ST segment depression differs in patients with coronary artery disease and patients with angina and normal coronary arteries, the exercise tests of 54 patients wit... | cardiovascular diseases |
Acute tumor lysis syndrome after intrathecal methotrexate administration. A 44-year-old man had acute tumor lysis syndrome after a single dose of intrathecal methotrexate was administered for lymphomatous meningitis (high-grade, small noncleaved B-cell) in the setting of untreated systemic disease. The metabolic derang... | general pathological conditions |
Myotonic dystrophy: quantification of muscle weakness and myotonia and the effect of amitriptyline and exercise. The purpose of this study was to quantify the degree of muscle weakness and myotonia in 12 patients with myotonic dystrophy (MD), and to quantitatively determine the effects of a four- to six-month therapeut... | general pathological conditions |
Fusiform dilatations of the carotid artery following radical surgery of childhood craniopharyngiomas. Between 1982 and 1990, a series of 31 children with craniopharyngiomas underwent initial surgery at the Children's Hospital of Philadelphia with an attempt at total tumor removal. Nine (29%) of them were found to have ... | cardiovascular diseases |
Development and validation of an index for scoring baseline respiratory disease in the very low birth weight neonate. Severity Index Development and Validation Panels and Newborn Lung Project. An accurate description of the population at risk for neonatal chronic lung disease is clearly of prime importance for comparat... | general pathological conditions |
Prevalence of angioid streaks and other ocular complications of Paget's disease of bone. Seventy randomly selected patients with Paget's disease of bone were examined for ocular complications. The prevalence of macular degeneration and cataract was 24.3%. Only one patient was found to have angioid streaks. Eight patien... | general pathological conditions |
Function after amputation, arthrodesis, or arthroplasty for tumors about the knee. We studied the function of twenty-two patients who had had a malignant skeletal tumor adjacent to the knee. An above-the-knee amputation was done in seven; a resection arthrodesis, in nine; and a replacement arthroplasty, in six. The pat... | neoplasms |
Ureteral stump carcinoma incidentally found at cystectomy for bladder cancer. We report on a sixty-five-year-old man with hematuria secondary to superficial bladder cancer. Because of previous urethral trauma, a complete transurethral resection of his bladder tumor could not be done. He, therefore, underwent cystectomy... | neoplasms |
Modified technique of Pringle's maneuver in resection of the liver. Crushing of the hepatic parenchyma with hepatic clamps to minimize blood loss during resection of the liver leads to mechanical damage of hepatocytes. Pringle's maneuver may precipitate liver failure by hepatic warm ischemia as well. Therefore, we cont... | neoplasms |
Endoscopic ultrasonography in diagnosis of the extent of gallbladder carcinoma. Endoscopic ultrasonography (EUS) was performed preoperatively in 39 patients with gallbladder carcinoma. Diagnosis of the anatomical extent of gallbladder carcinoma was compared with histologic analysis, and staging accuracy was evaluated a... | neoplasms |
Wives of coronary high-risk men--are they also at higher risk? The Tromso Heart Study. Blood lipids, blood pressure, body mass index (BMI), smoking, dietary and exercise habits were studied in 911 wives of men with high risk for coronary heart disease (CHD). Following the 1979/80 Tromso Survey, 1373 men, aged 30-54 yea... | cardiovascular diseases |
Vascular hypertrophy, renin and blood pressure in the young spontaneously hypertensive rat. 1. Cardiovascular reactivity, blood vessel morphology, blood pressure and the activity of the renin-angiotensin system were determined in the 3-week-old spontaneously hypertensive (SHR), Wistar-Kyoto (WKY) and outbred Wistar (WI... | cardiovascular diseases |
Surgery for thoracoabdominal aortic aneurysms. From July 1985 to July 1989, Loma Linda University Medical Center evaluated 46 thoracoabdominal aortic aneurysms (TAAAs). Forty patients were taken to surgery--18 (45%) were operated on an emergency basis for reasons including rupture (12 patients, 30%), dissection (5 pati... | general pathological conditions |
Indirect revascularization of the lower extremity by means of microvascular free-muscle flap--a preliminary report. We describe the treatment of a patient with end-stage peripheral vascular disease and ischemic ulceration of the lower extremity in whom an obliteration of the distal arterial bed precluded conventional a... | cardiovascular diseases |
Management of renovascular disease. A surgical perspective. The role of surgical revascularization in the management of patients with renal artery disease has changed in recent years. This has occurred due to the advent of percutaneous transluminal angioplasty as an effective method of treatment for certain patients, i... | cardiovascular diseases |
Giant cell versus lymphocytic myocarditis. A comparison of their clinical features and long-term outcomes BACKGROUND. Giant cell myocarditis has rarely been diagnosed premortem, and little is known about its natural history. In addition, no comparative studies with lymphocytic myocarditis exist. METHODS AND RESULTS. Th... | cardiovascular diseases |
The failure of serial pneumatic cuff venous occlusion plethysmography to predict patients at risk for pulmonary emboli after trauma. Over a three month period, attempts to perform serial Pneumatic Cuff Venous Occlusion Plethysmography (VP) were carried out in 51 severely injured patients felt to be at risk for Pulmonar... | cardiovascular diseases |
Primary non-Hodgkin's T-cell lymphoma of the esophagus. A case with peculiar endoscopic ultrasonographic pattern. We report a case of primary esophageal non-Hodgkin's T-cell lymphoma in a young white female. At admission, endoscopy revealed large, irregularly shaped, esophageal ulcerations with super imposed candidiasi... | neoplasms |
Randomised, double-blind, placebo-controlled trial of nimodipine in acute stroke. Trust Study Group. The value of oral nimodipine 120 mg per day for acute stroke was assessed in a randomised, double-blind, placebo-controlled multicentre study of 1215 patients. The primary end-point was independence after 6 months, defi... | general pathological conditions |
Thyroid crises. In the setting of characteristic features of thyrotoxicosis, the timely diagnosis and aggressive management of thyroid storm should result in a successful outcome. However, severe storm may lead to irreversible cardiovascular collapse, especially in the older patient who may have atypical features of th... | general pathological conditions |
Effect of intracoronary serotonin on coronary vessels in patients with stable angina and patients with variant angina BACKGROUND. Serotonin, a major product of platelet activation, has potent vasoactive effects in animal models, but its role in human coronary artery disease remains largely speculative. METHODS. Using q... | cardiovascular diseases |
A consensus approach to electrolytes and blood pressure. Could we all be right? This commentary sets forth the hypothesis that the putative beneficial or detrimental effects of specific electrolytes on blood pressure regulation in fact reflect highly integrated responses to interactions among these cationic and anionic... | cardiovascular diseases |
Activated protooncogenes in human lung tumors from smokers. Fourteen primary human lung tumor DNAs from smokers were analyzed for transforming activity by two DNA transfection assays. Activated protooncogenes were detected in 3 of 11 tumor DNAs by the NIH 3T3 focus assay, whereas activated protooncogenes were detected ... | neoplasms |
Balloon angioplasty of stenosed Blalock-Taussig anastomosis: role of balloon-on-a-wire in dilating occluded shunts. Six children with cyanotic congenital heart defects, aged 6 to 60 months, underwent percutaneous balloon angioplasty of a narrowed Blalock-Taussig (BT) shunt to improve arterial oxygen saturation. The ind... | general pathological conditions |
Delayed hearing loss after neurovascular decompression. We report two unusual cases of delayed hearing loss after neurovascular decompression of structures within the cerebellopontine angle. In the first case, the patient noted a unilateral hearing loss 3 weeks after undergoing vascular decompression of the trigeminal ... | nervous system diseases |
Sensitivity of a set of myocardial infarction screening criteria in patients with anatomically documented single and multiple infarcts. A subset of 3 screening criteria (Q wave greater than or equal to 30 ms in lead aVF, any Q or R wave less than or equal to 10 ms and less than or equal to 0.1 mV in lead V2, and R wave... | cardiovascular diseases |
Flexion-extension views in the evaluation of cervical-spine injuries. STUDY OBJECTIVE: To determine the efficacy of flexion-extension (F/E) cervical-spine radiographs in detecting acute cervical-spine instability in emergency patients. DESIGN: We retrospectively reviewed the charts of 141 consecutive trauma patients wh... | general pathological conditions |
Treatment of patients with isolated axillary nodal metastases from an occult primary carcinoma consistent with breast origin. The records of 42 patients who had axillary metastases compatible with a clinically occult breast primary were reviewed. Forty patients had mammography performed as part of their evaluations. Ma... | neoplasms |
Umbilical cord ulceration and intestinal atresia: a new association? In three fetuses, congenital intestinal atresia was associated with linear ulcerations of the umbilical cord. In two cases, hemorrhage was seen from the cord ulcer. Both fetuses required emergency cesarean section for fetal distress and were born anem... | general pathological conditions |
Loss of chromosome 22 alleles in human sporadic spinal schwannomas. Acoustic neuromas occur either as sporadic solitary tumors in the general population or as inherited bilateral tumors typically in patients with neurofibromatosis type 2. Loss of heterozygosity for markers on the long arm of chromosome 22 has been repo... | nervous system diseases |
Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome Tumour suppressor genes, whose usual function seems to be controlling normal cell proliferation, have been implicated in many inherited and sporadic forms of malignancies Much evidence supports the concept of tumour formatio... | neoplasms |
Disposition of cerebral metastases from malignant melanoma: implications for radiosurgery Radiosurgery is becoming more generally available and indications for its use continue to be defined. Cerebral metastases from malignant melanoma are often treated with whole-brain irradiation, but with limited benefit. Innovative... | neoplasms |
Genetics of asthma and hay fever in Australian twins. The occurrence of self-reported asthma/wheezing and hay fever among 3,808 pairs of twins from the Australian National Health and Medical Research Council Twin Registry was examined for evidence of genetic transmission by path analytic methods. The cumulative prevale... | general pathological conditions |
Changes in plasma free fatty acids and glycerols during prolonged exercise in trained and hypertensive persons taking propranolol and pindolol. The extent to which lipolysis is attenuated during prolonged submaximal exercise during beta blockade was determined in 12 normotensive endurance-trained and 12 hypertensive se... | cardiovascular diseases |
Tracheoesophageal anastomosis for intractable aspiration pneumonia. Permanent tracheostomy and tracheoesophageal anastomosis were performed as a means of surgical intervention for the treatment of intractable aspiration pneumonia. Conventional methods of tracheoesophageal anastomosis have entailed various problems. The... | general pathological conditions |
Milk protein enteropathy after acute infectious gastroenteritis: experimental and clinical observations. Animal models of allergic gastroenteropathy have defined both morphologic and physiologic changes that accompany the immune-mediated reaction to a dietary protein. In such models a broadening of the allergic respons... | digestive system diseases |
An epidemic outbreak of cryptosporidiosis: a prospective community study from Guinea Bissau. In the first year of a prospective community study of childhood diarrhea conducted in a semiurban area in the capital of Guinea Bissau, Cryptosporidium sp. was found in 73 (6.0%) of 1216 episodes of diarrhea. The parasite was t... | digestive system diseases |
Magnetic resonance imaging of small hepatocellular carcinoma. Thirty-eight patients with small hepatocellular carcinomas (HCCs), size less than 20 mm, initially detected by ultrasound (US) and histologically confirmed, were examined by magnetic resonance (MR) imaging, computed tomographic (CT) scan, and angiography. MR... | neoplasms |
High- versus standard-dose megestrol acetate in women with advanced breast cancer: a phase III trial of the Piedmont Oncology Association. One hundred seventy-two patients with advanced breast cancer were randomized to receive oral standard-dose megestrol acetate (MA), 160 mg/d or high-dose MA, 800 mg/d. All but two pa... | neoplasms |
Expression of blood group antigens H-2, Le(y), and sialylated-Le(a) in human colorectal carcinoma. An immunohistochemical study using double-labeling techniques. In this study, double-labeling immunohistochemistry was used to gain insight into the coexpression or interrelationship between blood group antigens (BGA) tha... | neoplasms |
The glucose transporter and blood-brain barrier of human brain tumors. The glucose transporter of the human brain has been localized to endothelial cells expressing the blood-brain barrier, but little is known regarding its mechanism of induction or whether its expression is exclusively linked with restricted vascular ... | neoplasms |
Renal artery stenosis: evaluation with color Doppler flow imaging. Renal artery stenosis (RAS) is the most common correctable cause of hypertension. The current study was undertaken to evaluate the usefulness of color Doppler flow imaging as a screening examination in the detection of significant RAS. Fifty-five kidney... | cardiovascular diseases |
Causes of failure after repeat vitreoretinal surgery for recurrent proliferative vitreoretinopathy. During the last two years, we performed vitreoretinal surgery on 37 eyes with retinal detachments and recurrent severe proliferative vitreoretinopathy in 37 patients who had had previous failed scleral buckling and vitre... | general pathological conditions |
Unilateral asterixis. We describe three patients with unilateral asterixis. One diabetic patient with a moderately-sized haematoma in the left putamen initially developed bilateral and symmetrical asterixis, which became confined to the right side as his diabetes mellitus was controlled. Two patients showed unilateral ... | general pathological conditions |
Non-Hodgkins lymphoma of the head and neck: experience in the Grampian area. The records of 44 cases of non-Hodgkins lymphoma (NHL) presenting to the ear, nose and throat department in the Grampian area from 1980-1988 were examined in relation to site of occurrence, histology, age at presentation, clinical stage, treat... | neoplasms |
Regional differences in the intranodal distribution of tumor cells. The intranodal distribution of tumor cells was examined in 103 mesenteric and 135 axillary nodes to determine the frequency of a circumferential type of distribution and its relationship, if any, to central necrosis. Eighteen percent of the mesenteric ... | neoplasms |
Blue rubber bleb nevus syndrome with oral hemangiomas. A case of blue rubber bleb nevus syndrome with oral hemangiomas is reported. Attention is directed to this syndrome because, although rare, it is usually associated with oral lesions. The blue rubber bleb nevus syndrome should always be considered a possibility in ... | general pathological conditions |
Phase I clinical and pharmacokinetic trial of flavone acetic acid. Flavone acetic acid is a synthetic benzopyrone derivative with an unknown mechanism of action. Thirty-eight patients (30 men and 8 women) were treated once a week for 4 weeks every 5 weeks with doses of flavone acetic acid ranging from 0.33 to 12.5 g/m2... | neoplasms |
Intraoperative radiation of canine carotid artery, internal jugular vein, and vagus nerve. Therapeutic applications in the management of advanced head and neck cancers. As a step in the application of intraoperative radiotherapy (IORT) for treating advanced head and neck cancers, preliminary information was obtained on... | neoplasms |
Osteosarcoma of the maxilla in Hong Kong Chinese postirradiation for nasopharyngeal carcinoma. A report of four cases. Postirradiation osteosarcoma of the maxilla was seen in four Hong Kong Chinese patients treated for nasopharyngeal carcinoma. These cases represent four of 42 (9%) cases of osteosarcoma at all sites in... | neoplasms |
Mutation of the p53 gene in human acute myelogenous leukemia. Heterogeneity of p53 protein expression is seen in blast cells of patients with acute myelogenous leukemia (AML). p53 protein is detected in the blasts of certain AML patients but not in others. We have identified p53 protein variants with abnormal mobility ... | general pathological conditions |
The utility of echocardiography in the diagnostic strategy of postinfarction ventricular septal rupture: a comparison of two-dimensional echocardiography versus Doppler color flow imaging. The diagnostic accuracy of Doppler color flow imaging in the diagnosis of postinfarction ventricular septal defects has not been es... | cardiovascular diseases |
Preferential localization of human adherent lymphokine-activated killer cells in tumor microcirculation. The efficacy of adoptive immunotherapy for solid tumors with lymphokine-activated effector cells presumably depends on the ability of these cells to localize adequately in tumor tissues. We present here the first qu... | neoplasms |
Peripheral arterial occlusive disease of the extremities in the United States: hospitalization and mortality. PAODE is an important cause of morbidity and health care expenditures among the elderly. Data from the NHDS and National Vital Statistics System were used to assess its impact in the U.S. In 1985 to 1987, an es... | cardiovascular diseases |
Quantification of vascular stenosis with color Doppler flow imaging: in vitro investigations. The accuracy of quantifying the degree of vascular stenosis with color Doppler flow imaging (7.5-MHz, linear array system) was determined in an experimental study carried out on six concentric and five eccentric model stenoses... | cardiovascular diseases |
Lung injury in a surfactant-deficient lung is modified by indomethacin. Repetitive total lung lavage in adult rabbits leads to a reproducible severe surfactant-deficient lung injury. Hypoxemia requiring mechanical ventilation occurs, accompanied by a substantial pulmonary hypertension, a large intra-alveolar protein le... | cardiovascular diseases |
Cisplatin-fluorouracil interaction in a squamous cell carcinoma xenograft. Patients with squamous cell carcinoma of the head and neck are treated with cisplatin and fluorouracil according to a schedule based on the findings of clinical studies. A similar schedule showed a supra-additive effect in the treatment of xenog... | neoplasms |
Evaluation of preoperative computed tomography in gastric malignancy. Ninety patients with gastric malignancy underwent computed tomography (CT) before surgery. The CT findings regarding neoplastic invasion of adjacent organs and metastasis or enlarged lymph nodes were compared with the findings at laparotomy (85 cases... | neoplasms |
Effects of short spaceflights on mechanical characteristics of rat muscles. The aim of this study was to investigate the contractile protein characteristics after 5-day (Cosmos 1514) and 7-day (Cosmos 1667) spaceflights. The experiments were performed on skinned fibers from the soleus, gastrocnemius lateralis, and plan... | nervous system diseases |
Preventing stroke by the modification of risk factors. Epidemiologic research has revealed the major risk factors in cerebrovascular disease. This review will concentrate on three important risk factors: elevated blood pressure, the most common and important, since it is responsible for up to 70% of all strokes; raised... | nervous system diseases |
Visual evoked potentials and visual prognosis following perinatal asphyxia. Twenty-five children born at term with perinatal asphyxia were studied at age 2.5 to 4.5 years to evaluate visual function and to determine the prognostic value of postnatal assessments of visual outcome. Postnatal assessments included several ... | nervous system diseases |
Muscle fatigue in McArdle's disease. Muscle fibre conduction velocity and surface EMG frequency spectrum during ischaemic exercise. The origin of fatigue in McArdle's disease is still a matter of debate. Both a reduction of muscle membrane excitability and failure of excitation-contraction (E-C) coupling have been sugg... | cardiovascular diseases |
Hematoma of the optic nerve sheath after penetrating trauma. We have presented a case involving the diagnosis and management of optic nerve sheath hematoma. Our patient's positive outcome demonstrates the usefulness of megadose steroid therapy for acute optic nerve injury. | general pathological conditions |
Complete remission in refractory anaplastic adult Wilms' tumor treated with cisplatin and etoposide. A 61-year-old woman underwent a left radical nephrectomy for Stage II anaplastic Wilm's tumor. She received no adjuvant therapy. One year later computerized tomography (CT) of the abdomen revealed a mass in the left ren... | neoplasms |
Intraoperative assessment of cerebral ischemia during carotid surgery. One of the problems in carotid surgery is the intraoperative detection of brain ischemia. None of the methods (EEG; stump pressure) applied so far have been successful. Branston et al. (1974) found a threshold relationship between cortical cerebral ... | general pathological conditions |
Renal function after tumor enucleation in a solitary kidney. Whether extensive ablation of renal mass in humans leads to progressive glomerulosclerosis, proteinuria, and hypertension, as it does in animal models, is a matter of controversy. We have studied kidney function in six patients who underwent enucleation of a ... | neoplasms |
Glucagonoma syndrome is an underdiagnosed clinical entity. Glucagonomas, considered among the rarest of the islet cell neoplasms, produce a well-defined clinical syndrome characterized by necrolytic migratory erythema, diabetes mellitus, glossitis, anemia, and weight loss. This report describes seven patients with gluc... | general pathological conditions |
Congenital angiotropic lymphoma (intravascular lymphomatosis) of the T-cell type. The autopsy of a stillborn infant showed an extensive intravascular proliferation of atypical cells throughout the body. There was no infiltration by these cells of the parenchyma of the bone marrow, lymph nodes, or thymus. By histochemis... | neoplasms |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.