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Fish oil supplementation in patients with stable claudication. Increased blood viscosity occurs in patients with claudication. This increase in viscosity, which is mainly due to elevated fibrinogen levels and a decreased red cell deformability, adversely influences blood flow. In addition to a positive effect on blood ... | cardiovascular diseases |
Meralgia paresthetica after coronary bypass surgery. Meralgia paresthetica is a neurologic disorder characterized by localized paresthesia and numbness on the anterolateral aspect of the thigh and involving the lateral femoral cutaneous nerve. It involves no motor deficits. Meralgia paresthetica, which may result from ... | nervous system diseases |
Unusual opening of coronary sinus in atrioventricular septal defects. The coronary sinus is an important landmark for the position of the atrial component of the atrioventricular conduction axis and, thus, assumes special relevance to the surgeon in the operating room. We describe here 2 patients with atrioventricular ... | cardiovascular diseases |
Should urologists wear spectacles for transurethral resection of the prostate? Contamination of the eyes by irrigation fluid during transurethral resection (TUR) of the prostate was assessed by measuring droplet splashes on to spectacles worn by 2 surgeons. During 30 consecutive operations, droplet splash contamination... | digestive system diseases |
Nucleolar organizer regions in precancerous and cancerous lesions of the bronchus. Using a silver staining technique, nucleolar organizer region-associated proteins (Ag-NOR) were studied in paraffin sections of five specimens of normal bronchial epithelium, eight of atypical squamous metaplasia, five of carcinoma in si... | neoplasms |
Bcr/abl recombinant DNA analysis versus karyotype in the diagnosis and therapeutic monitoring of chronic myeloid leukemia. Karyotype and bcr/abl recombinant DNA analyses are two means of detecting the chromosomal aberration in chronic myeloid leukemia. The authors compared these two methods in a retrospective study of ... | neoplasms |
Echocardiographic evaluation of cardiac structure and function in elderly subjects with isolated systolic hypertension One hundred four participants in the Systolic Hypertension in the Elderly Program (SHEP) trial (mean age 71 +/- 6 years) were examined by Doppler echocardiography to gain information on the cardiac str... | cardiovascular diseases |
Truncal vagotomy and pyloroplasty combined with valvular replacement in patients with ulcer disease. In 1988, 5 patients (3 men and 2 women) with ulcer disease (mean age 56 +/- 8 years) underwent valvular replacement for aortic (No. = 4) or mitral disease (No. = 1). All patients had had gastroduodenal ulcers. Preoperat... | general pathological conditions |
Peritoneal dialysis in the geriatric patient. Elderly patients on chronic peritoneal dialysis (CPD) from two large chronic peritoneal dialysis programs were compared with younger patients in regard to peritonitis rates, catheter problems, hospital days, transfers to other forms of therapy, and mortality. Peritonitis ra... | digestive system diseases |
Gallbladder varices: imaging findings in patients with portal hypertension. A retrospective review of the medical and imaging records of 50 patients with portal hypertension examined in the authors' department during a 2-year period identified six patients with gallbladder wall varices. Imaging studies performed in the... | digestive system diseases |
Paraplegia after a routine lumbar laminectomy: report of a rare complication and successful management. Arachnoid cysts of the spinal canal are relatively common lesions that may be either intra- or extradural. These cysts are usually asymptomatic but may produce symptoms by compressing the spinal cord or nerve roots. ... | nervous system diseases |
Conduction system injury after aortic valve dilation in the dog single- versus double-balloon catheters. The range of morbidity induced by valvuloplasty is not fully known, but transient conduction disturbances are common. The authors performed aortic valve balloon dilatation on 10 closed-chest dogs with normal aortic ... | general pathological conditions |
Assessment of Proplast-Teflon disc replacements [published erratum appears in J Oral Maxillofac Surg 1991 Feb;49(2):220] This retrospective study reports the findings in the follow-up of 31 temporomandibular joints in which Proplast-Teflon (Vitek Inc, Houston, TX) replacements were used. Among the problems noted were p... | general pathological conditions |
Relief of tracheal compression by aortopexy. We have performed aortopexy in 12 children with tracheal compression. Six infants had compression secondary to a vascular anomaly (group 1), and the other 6 had previous repair of esophageal atresia (group 2). Eleven of the 12 children are alive after a mean follow-up of 36 ... | digestive system diseases |
Supraventricular tachycardia due to Wolff-Parkinson-White syndrome in children: early disappearance and late recurrence The clinical course of 140 patients with Wolff-Parkinson-White syndrome who had their initial episode of supraventricular tachycardia before 18 years of age was reviewed. Among those whose tachycardia... | cardiovascular diseases |
Esophageal reflux before and after isolated myotomy for achalasia. Four patients with achalasia underwent 24-hour esophageal pH measurements as ambulatory patients before and after limited myotomy without fundoplication. Resting lower esophageal sphincter pressure was reduced from 24.3 +/- 1.3 mm Hg to 7.5 +/- 4.3 mm H... | digestive system diseases |
A rodent model of cirrhosis, ascites, and bacterial peritonitis. We sought to develop a rodent model of spontaneous bacterial peritonitis and report here the preliminary results of carbon tetrachloride-induced cirrhosis in which ascites and bacterial peritonitis predictably develop. Of 41 rats that survived the initial... | digestive system diseases |
Usefulness of epidurally evoked cortical potential monitoring during cervicomedullary glioma surgery. This report describes a patient with an intramedullary ependymoma at the region of the cervicomedullary junction in whom there was an abolition of somatosensory evoked potentials following median nerve stimulation. Dur... | neoplasms |
Management of symptomatic lymphocele via percutaneous drainage and sclerotherapy with tetracycline. Lymph collections following pelvic surgery are usually asymptomatic, but may occasionally produce symptoms requiring invasive therapy. We have successfully obliterated a large lymphocele by employing percutaneous drainag... | neoplasms |
Tympanosclerosis of the middle ear: late results of surgical treatment. The late results of one stage operation for middle ear tymanosclerosis in 73 patients during the period January 1965 to December 1980 are presented. Mean observation time was 11.2 years (range 3-20.2 years), with a follow-up rate 86 per cent. Among... | general pathological conditions |
Clinical cardiovascular magnetic resonance imaging. Magnetic resonance imaging (MRI) is a powerful tool providing high-resolution images of the heart and great vessels without the use of ionizing radiation or contrast agents. MRI systems currently in use at many hospitals can be used effectively in the routine, clinica... | cardiovascular diseases |
Bronchial mucus hypersecretion in acute quadriplegia. Macromolecular yields and glycoconjugate composition. In acute quadriplegia we have noted that about one in five patients develops unexplained production of markedly excessive and tenacious bronchial mucus. Spontaneous recovery from mucus hypersecretion usually occu... | nervous system diseases |
Fractionated high dose rate versus low dose rate regimens for intracavitary brachytherapy of the cervix. I. General considerations based on radiobiology. Intracavitary brachytherapy at low dose rate (LDR), often with the addition of external-beam radiotherapy, has long been considered the treatment of choice for carcin... | neoplasms |
Diagnostic and prognostic value of electrophysiologic tests in meralgia paresthetica. Electrophysiologic diagnosis of unilateral meralgia paresthetica is usually assessed by side-to-side comparison of SNAP amplitudes, SNCVs, and SEP latencies following stimulation of lateral femoral cutaneous nerves. To determine the r... | nervous system diseases |
A comparison of induction and maintenance therapy for acute nonlymphocytic leukemia in childhood: results of a Pediatric Oncology Group study. Two hundred fifty-six children with previously untreated acute nonlymphocytic leukemia (ANLL) were evaluated on a Pediatric Oncology Group (POG) phase III randomized trial of bo... | neoplasms |
Calcium antagonists in the management of patients with aneurysmal subarachnoid hemorrhage: a review. Cerebral arterial vasospasm and infarction is the leading cause of death and disability among patients who reach a major medical center after aneurysmal subarachnoid hemorrhage (SAH). Recent evidence suggests that two c... | cardiovascular diseases |
Detection of restenosis after successful coronary angioplasty: improved clinical decision making with use of a logistic model combining procedural and follow-up variables. A prospective study of 111 patients who underwent repeat coronary angiography and exercise thallium-201 scintigraphy 6 +/- 2 months after complete r... | general pathological conditions |
Simultaneous superior oblique sheathectomy and inferior oblique tuck in congenital Brown's syndrome. Since Harold Brown, in 1950, described the superior oblique tendon sheath syndrome, numerous surgical techniques have been explored to treat this condition. Tenectomy of the homolateral superior oblique, alone or in com... | general pathological conditions |
Myasthenic thymus and thymoma are selectively enriched in acetylcholine receptor-reactive T cells. We compared T-cell proliferative responses to acetylcholine receptor (AChR) and to purified protein derivative (PPD) (of tuberculin) of hyperplastic thymus, thymoma, and blood cells from patients with myasthenia gravis (M... | nervous system diseases |
The risk of large bowel cancer after partial gastrectomy for benign ulcer disease. The relative risk (standardized incidence ratio [SIR] for colorectal cancer after partial gastrectomy for ulcer disease was examined in a population-based cohort comprising 6459 patients operated during 1950 to 1958. Follow-up through 19... | digestive system diseases |
Double-peaking circadian variation in the occurrence of sustained supraventricular tachyarrhythmias. We studied 251 patients less than or equal to 65 years of age admitted for treatment of symptomatic supraventricular tachyarrhythmia to assess whether these arrhythmias begin evenly throughout the day or manifest circad... | cardiovascular diseases |
Automated immunohistochemical estrogen receptor in fixed embedded breast carcinomas. The authors immunohistochemically assessed the presence of estrogen receptor (ER) in formalin-fixed, paraffin-embedded tissue sections of 68 breast carcinomas by an automated method using Pronase (CalBiochem, La Jolla, CA) predigestion... | neoplasms |
Pancreaticopleural fistula. Report of 7 patients and review of the literature. Pancreaticopleural fistula is an uncommon clinical condition. Its presentation is often confusing because of the paucity of clues suggestive of pancreatic disease and the preponderance of pulmonary symptoms and signs. Most patients are alcoh... | digestive system diseases |
Management of mycotic rupture of the ascending aorta after heart-lung transplantation. A 19-year-old woman underwent heart-lung transplantation for obstructive bronchiolitis. Eleven days later mycotic rupture of the ascending aorta occurred. Emergency cardiopulmonary bypass was instituted via the femoral vessels and th... | cardiovascular diseases |
Miscellaneous adverse effects of low-versus high-osmolality contrast media: a study revised The authors analyzed data from two recent articles in Radiology in which the quality and results of randomized control trials (RCTs) comparing the efficacy or safety of the low-osmolality contrast media (LOM) iopamidol, iohexol,... | digestive system diseases |
Ovarian granulosa-stromal cell tumors are characterized by trisomy 12. Eleven ovarian granulosa-stromal cell tumors including 1 thecoma, 2 fibromas, 6 fibrothecomas, and 2 granulosa cell tumors, were karyotyped after direct harvest and/or short-term tissue culture. Bilateral fibrothecomas from one patient appeared to l... | general pathological conditions |
Mechanisms associated with the generation of biologically active human immunodeficiency virus type 1 particles from defective proviruses. The human immunodeficiency virus (HIV) is the etiological agent of acquired immunodeficiency syndrome (AIDS). HIV exhibits extensive genetic diversity and it is apparent that an infe... | neoplasms |
Which clinical variables predict an abnormal double-contrast barium enema result? OBJECTIVE: To determine the relations among patient history, symptoms, objective indicators, and abnormal double-contrast barium enema results in outpatients. PATIENTS AND SETTING: Seven hundred and ninety-four patients receiving care in ... | neoplasms |
Hyperfunctioning metastatic follicular thyroid carcinoma in Pendred's syndrome. A 66-year-old woman with Pendred's syndrome underwent a partial thyroidectomy when she was 17 years old. At the age of 52 years, she had a second thyroid operation because of hyperthyroidism due to a toxic multinodular goiter with a mediast... | neoplasms |
Bronchobiliary fistula detected by cholescintigraphy. We present a case of a bronchobiliary fistula initially detected by hepatobiliary scintigraphy. The patient developed bilioptysis 18 mo after undergoing a right hepatic lobectomy and resection of the common bile duct for cholangiocarcinoma. The procedure was complic... | digestive system diseases |
Granulocytic sarcoma presenting as an epidural mass with acute paraparesis in an aleukemic patient. Granulocytic sarcomas are rare tumors composed of granulocytic precursor cells. They are most commonly encountered in patients with acute myelogenous leukemias and myeloproliferative disorders in blast crisis. Rarely, pa... | nervous system diseases |
Membrane oxygenator prevents lung reperfusion injury in canine cardiopulmonary bypass The effect of blood activation on lung reperfusion injury during cardiopulmonary bypass was investigated in 20 dogs with the use of a bubble oxygenator (n = 10) or a membrane oxygenator (n = 10). In the bubble oxygenator group, signif... | general pathological conditions |
Skeletal manifestations of ectopic or inappropriate endocrine and metabolic syndromes. A variety of tumors and nontumorous lesions were used to illustrate some of the biologic, clinical, and pathologic aspects of inappropriate or ectopic endocrine and metabolic syndromes that have musculoskeletal repercussions. It is c... | neoplasms |
Lesions that manifest as medial cheek and nasolabial fold masses. Seventeen cases were collected in which the patient presented with a medial cheek or nasolabial fold mass. Most of these lesions were uncommon, and some were rare. The most reliable differentiating finding was the type of associated bone involvement. The... | neoplasms |
Major histocompatibility complex genes and susceptibility to systemic lupus erythematosus. Susceptibility to systemic lupus erythematosus is associated with major histocompatibility complex (MHC)--encoded genes. We have used nucleotide sequence analysis to better define the disease-associated MHC alleles. HLA-DR2, DQw1... | general pathological conditions |
Hemodynamics in internal carotid artery occlusion examined by positron emission tomography. Using positron emission tomography in nine patients with minor strokes, unilateral internal carotid artery occlusion, and good collateral circulation through the anterior portion of the circle of Willis, we analyzed regional cer... | cardiovascular diseases |
Modification of atrioventricular node transmission properties by intraoperative neodymium-YAG laser photocoagulation in dogs. The purpose of this study was to test the feasibility of neodymium-yttrium-aluminum-garnet (Nd-YAG) laser photocoagulation of the atrioventricular (AV) node to control the ventricular rate durin... | cardiovascular diseases |
Prognostic value of thallium-201 perfusion defects in idiopathic dilated cardiomyopathy. To assess the prognostic significance of thallium-201 perfusion defects in patients with idiopathic dilated cardiomyopathy (IDC), 43 patients underwent thallium scintigraphy in addition to clinical, echocardiographic, angiographic ... | cardiovascular diseases |
Eustachian valve endocarditis. M mode and cross sectional echocardiography showed a highly mobile globular pedunculated mass(3.0 cm long with a maximum diameter of i.5 cm) attached to the eustachian valve in a heroin addict with staphylococcal endocarditis. | cardiovascular diseases |
Aneuploidy in pancreatic insulinomas does not predict malignancy. Nuclear deoxyribonucleic acid (DNA) ploidy studies with paraffin embedded archival material from 14 pancreatic insulinomas were performed by flow cytometry. Clinical follow-up (2 to 17 years; mean, 8 years) was obtained for all patients. Half of the tumo... | neoplasms |
Heterotopic liver transplantation for fulminant Wilson's disease. Wilson's disease may present with severe acute hepatocellular failure. The only effective treatment for fulminant Wilson's disease is liver transplantation, which may lead to reversal of the underlying disease. Some patients with cirrhosis who are too il... | digestive system diseases |
Selective pulmonary vasodilation with ATP-MgCl2 during pulmonary hypertension in lambs. We investigated the effects of infusions of ATP-MgCl2 on the circulation in 11 spontaneously breathing newborn lambs during pulmonary hypertension induced either by the infusion of U-46619, a thromboxane A2 mimetic, or by hypoxia. D... | cardiovascular diseases |
Treatment of metastatic melanoma with an autologous tumor-cell vaccine: clinical and immunologic results in 64 patients. We treated 64 patients with metastatic melanoma using a melanoma vaccine preceded by low-dose cyclophosphamide (CY), and monitored immunologic effects and antitumor activity. On day 0, the patients w... | general pathological conditions |
Kinematic analysis of lower-limb movement during ergometer pedaling in hemiplegic and nonhemiplegic subjects. The purpose of this descriptive study was to examine bicycle pedaling as a model for studying motor control dysfunction in persons with hemiplegia. Results of a kinematic analysis of the involved lower extremit... | general pathological conditions |
Cingulin, a specific protein component of tight junctions, is expressed in normal and neoplastic human epithelial tissues. Cingulin is a 140-kd protein localized on the cytoplasmic face of avian tight junctions. The expression of cingulin in human normal and neoplastic colonic tissue has been investigated with an antis... | neoplasms |
Mononuclear phagocytes: a major population of effector cells responsible for rejection of allografted tumor cells in mice. To understand the in situ mechanism of immunological response of recipient animals to allografted tumor cells, the types of cells that infiltrated into the rejection site were examined. When Meth A... | neoplasms |
Cerebral tumor staging in patients with bronchial carcinoma by computed tomography. Computerized tomographic (CT) scans of 271 patients with histologically proven bronchial carcinoma accomplished for initial tumor staging were retrospectively evaluated for signs of cerebral metastasis. The results for the histologic su... | neoplasms |
Acute renal failure associated with the use of intraperitoneal carboplatin: a report of two cases and review of the literature. Carboplatin, a new analogue of cisplatin used in the treatment of ovarian carcinoma, has been demonstrated to be less nephrotoxic than its predecessor. To date, hundreds of cycles of therapy h... | neoplasms |
Integration of hepatitis B vaccination into rural African primary health care programmes. OBJECTIVE--To determine the efficacy of hepatitis B vaccine when added to the routine expanded programme on immunisation under field conditions in rural Africa. DESIGN--Infants were immunised according to two schedules--an early s... | digestive system diseases |
Epirubicin at two dose levels with prednisolone as treatment for advanced breast cancer: the results of a randomized trial. Two hundred eleven patients with advanced breast cancer were randomized to receive either epirubicin (E) 50 mg/m2 and prednisolone (LEP) or E 100 mg/m2 and prednisolone (HEP). The intended treatme... | cardiovascular diseases |
Infusion of a stable prostacyclin analogue, iloprost, to patients with peripheral vascular disease: lack of antiplatelet effect but risk of thromboembolism. PURPOSE: Prostacyclin, a potent inhibitor of platelet function and vasodilator, has been used to treat peripheral vascular disease. The aim of this study was to mo... | cardiovascular diseases |
Changes in plasma high density lipoprotein cholesterol and phospholipid in acute viral hepatitis and cholestatic jaundice. Forty-four male and female subjects aged 22-57 years were studied. Thirteen patients had acute viral hepatitis, and eleven patients had cholestatic jaundice due to carcinoma of the head of the panc... | neoplasms |
Combined modality therapy for locally advanced non-small cell lung carcinoma. Multi-modality treatment consisting of cisplatin, VP-16, and 5-fluorouracil chemotherapy given concomitantly with external beam radiation was used to treat 64 patients with locally advanced Stage III non-small cell lung carcinoma. This regime... | neoplasms |
Telephone use to elicit voice or speech in brain injured subjects. The initiation of speech is often delayed in the early stages of recovery from a serious brain injury. We have found a high percentage of patients with both speech and swallowing problems. This makes bedside assessment of swallowing safety difficult bec... | nervous system diseases |
Effects of hydralazine and prostaglandin E1 on regional myocardial function in the ischemic canine heart. The effects of hydralazine and prostaglandin E1 on regional myocardial function were studied in dogs. Sixteen dogs were randomly assigned to one of two drug treatment groups of eight dogs each. The first group (G1)... | cardiovascular diseases |
Miliary tuberculosis presenting as hepatic and renal failure. A 67-year-old man developed hepatic and renal failure over a six-day period. Despite full supportive measures, he died on his 11th day of hospitalization with fulminant DIC and hepatic, renal, and respiratory failure. Postmortem examination revealed acid-fas... | digestive system diseases |
Amplification by the polymerase chain reaction of hypervariable regions of the human genome for evaluation of chimerism after bone marrow transplantation. We combined the polymerase chain reaction (PCR) with oligonucleotide hybridization as a novel and sensitive technique to evaluate posttransplant chimerism. Specific ... | neoplasms |
Antithrombotic efficacy of continuous extradural analgesia after knee replacement. We have studied the effect of extradural analgesia on postoperative venous thrombosis in patients undergoing knee arthroplasty. Forty-eight patients were allocated randomly to receive either general anaesthesia or extradural analgesia wi... | cardiovascular diseases |
Association between DNA ploidy pattern and cellular atypia in colorectal carcinomas. A new clinical application of DNA flow cytometric study? Fresh tissue specimens from 406 colorectal carcinomas were analyzed by DNA flow cytometric study, and the DNA ploidy pattern was compared with Dukes' stage, histologic grade, and... | neoplasms |
Flow cytometric analysis of DNA content in partial hydatidiform moles with persistent gestational trophoblastic tumor. Hydatidiform moles may be classified as partial or complete based on genetic and pathologic criteria. Between January 1979 and January 1990, 17 (5.5%) of 310 patients followed for partial mole develope... | neoplasms |
Recurrent peritonitis: evidence for possible viral etiology. A 45-year-old woman who was treated with continuous ambulatory peritoneal dialysis (CAPD) developed recurrent peritonitis characterized by cloudy effluents, elevated white blood cell (WBC) counts (predominantly lymphocytes), and negative culture results. This... | digestive system diseases |
Improved scintigraphic assessment of severe cholestasis with the hepatic extraction fraction. In previous studies, we found that biliary scintigraphy with technetium-99m-labeled iminodiacetic acid ([99mTc]IDA) provided excellent discrimination between intrahepatic and extrahepatic cholestasis, except in patients with p... | digestive system diseases |
Renal manifestations of NaCl sensitivity in borderline hypertensive rats. Compared with the normotensive Wistar-Kyoto rat, the spontaneously hypertensive rat exhibits exaggerated alterations in renal sympathetic nerve activity and excretory function during volume expansion (exaggerated natriuresis) and environmental st... | cardiovascular diseases |
Subgroups of patients with atypical circadian patterns of symptom onset in acute myocardial infarction. Circadian variation of onset of acute myocardial infarction has been noted in many studies and may carry important implications. However, only a few previous studies have attempted subgroup analysis. In 4,796 patient... | cardiovascular diseases |
The UCLA-University of Utah epidemiologic survey of autism: the etiologic role of rare diseases. Twelve rare diseases known to cause CNS pathology were found in 26 (11%) of 233 autistic probands identified during a recent epidemiologic survey of Utah. These 26 probands had significantly lower mean IQs than the remainin... | nervous system diseases |
Relationship of transfusion and infectious complications after gastric carcinoma operations. To determine the effect of transfusion on the incidence of postoperative infection, a retrospective cohort study of 196 patients who underwent surgery for gastric carcinoma in the period from 1985 through 1989 was carried out. ... | general pathological conditions |
Coronary angioplasty of diffuse coronary artery disease. From January 1983 through December 1987, 98 patients underwent angioplasty of at least one diffusely diseased coronary artery. Diffuse coronary disease was described as: group I, narrowing greater than or equal to 50% that involved the entire vessel (40 patients)... | general pathological conditions |
Flow cytometry for clinical estimation of circulating hematopoietic progenitors for autologous transplantation in cancer patients. Optimum methods of harvesting circulating hematopoietic progenitors for autologous transplantation to support myeloablative cancer therapy are still uncertain, mostly because of the lack of... | neoplasms |
Primary malignant melanoma in the parotid gland. Reports of primary malignant melanoma arising from the parotid salivary gland are extremely rare and, to date, have been sporadic. We report a pertinent case, and tabulate and correlate the clinical findings of the 13 cases reported thus far in the literature. The most c... | neoplasms |
Magnetic resonance imaging of fourth ventricular epidermoid tumors. Two pathologically proved cases of epidermoid tumor of the fourth ventricle are presented; clinical history and computed tomographic, magnetic resonance imaging, and histopathologic findings are included. | nervous system diseases |
Platelet-derived growth factor receptor alpha-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation. Platelet-derived growth factor receptors are composed of two subunits (alpha and beta) that associate with one another to form three functionally active dimeric receptor species. The two subunits are encoded... | general pathological conditions |
Circulating antibodies against human colonic extract enriched with a 40 kDa protein in patients with ulcerative colitis. We have previously described a 40 kDa colonic protein(s) which is specifically recognised by tissue-bound immunoglobulin G obtained from the colon of patients with ulcerative colitis. We now report t... | digestive system diseases |
Brief angiotensin converting enzyme inhibitor treatment in young spontaneously hypertensive rats reduces blood pressure long-term Our study examines the long-term cardiovascular effects after a brief period of angiotensin converting enzyme (ACE) inhibitor treatment in young spontaneously hypertensive rats (SHR). SHR we... | cardiovascular diseases |
The opposite pupil in herniation. I serially examined the pupil opposite the one already enlarged from transtentorial herniation in 13 patients. The main abnormalities, stereotyped in most patients, were an initially diminished light reaction with a 2.5- to 4-mm-diameter pupil, followed by slight reduction in size, and... | nervous system diseases |
Inhaled albuterol and oral prednisone therapy in hospitalized adult asthmatics. Does aminophylline add any benefit? STUDY OBJECTIVE: To determine the efficacy of intravenous aminophylline in the treatment of adult patients hospitalized for exacerbation of asthma. DESIGN: Randomized, double-blind, placebo-controlled tri... | general pathological conditions |
Intravascular ultrasound imaging of an acute dissecting aortic aneurysm: a case report. A case of acute dissecting aortic aneurysm is described in which intravascular ultrasonography was used at the time of aortography to produce real-time, 360 degree cross-sectional images of the aorta. The transmural vessel morpholog... | general pathological conditions |
Temporal movement control in patients with Parkinson's disease. Patients with Parkinson's disease (PD) have been reported to be unable to modify their movement velocity to adapt to changing environmental demands. For example, when movement amplitude is varied, PD patients usually exhibit a nearly constant peak velocity... | nervous system diseases |
Experimental intravesical therapy for superficial transitional cell carcinoma in a rat bladder tumor model. A rodent bladder cancer model that is induced by intravesical instillation of N-methyl-N-nitrosourea (MNU) was characterized. Cohorts of four to five week old female Fisher 344 rats received four biweekly 1.5 mg.... | neoplasms |
Nitrous oxide does not alter infarct volume in rats undergoing reversible middle cerebral artery occlusion. This experiment was designed to determine if nitrous oxide alters neurologic and pathologic outcome from temporary focal cerebral ischemia in spontaneously hypertensive rats deeply anesthetized with a barbiturate... | cardiovascular diseases |
Effect of epinephrine and lidocaine therapy on outcome after cardiac arrest due to ventricular fibrillation. One hundred ninety-nine patients with out-of-hospital cardiac arrest persisted in ventricular fibrillation after the first defibrillation attempt and were then randomly assigned to receive either epinephrine or ... | general pathological conditions |
The role of aspiration cytologic examination in the diagnosis of carcinoma of the breast. A study of 2,000 patients who had undergone fine needle aspiration of a solid lump of the breast was conducted to determine the accuracy of this technique. During the period 1982 to 1989, all patients with a solid mammary mass, pr... | neoplasms |
Low-dose almitrine bismesylate enhances hypoxic pulmonary vasoconstriction in closed-chest dogs. The effect of almitrine bismesylate on the hypoxic pulmonary vasoconstrictor response was studied in six closed-chest dogs anesthetized with pentobarbital and paralyzed with pancuronium. The right lung was ventilated contin... | general pathological conditions |
Aortic calcified plaques and cardiovascular disease (the Framingham Study). The relation between the presence of calcified plaques in the thoracic aorta, as detected on chest x-rays, and the development of cardiovascular disease is examined during 12 years of follow-up of the Framingham cohort (n = 5,209). The prevalen... | general pathological conditions |
Surgery in patients on long-term steroid therapy: a tentative model for risk assessment. Increased morbidity after operation has been associated with long-term steroid therapy. To determine the correlation between steroid therapy and such morbidity, the perioperative course of 55 steroid-treated patients was reviewed: ... | general pathological conditions |
Early facial reanimation following radical parotid and temporal bone tumor resections. A retrospective study of 35 patients who underwent early facial reanimation following extirpative parotid and temporal bone surgery requiring facial nerve sacrifice was performed. Regional facial reanimation performed immediately or ... | general pathological conditions |
Evidence for the functional binding in vivo of tumor rejection antigens to antigen-presenting cells in tumor-bearing hosts. Spleen cells of BALB/c mice bearing a syngeneic CSA1M fibrosarcoma were treated with anti-Thy-1.2 antibody plus C, yielding a T cell-depleted, APC-containing fraction. The APC-containing fraction ... | neoplasms |
Beat-to-beat detection of ventricular late potentials with high-resolution electrocardiography. To detect dynamic changes of VLPs we developed a low-noise, HR-ECG with a gain of 10(5)-10(6)X. This system allows the beat-to-beat detection of low-amplitude signals at the bedside in a nonshielded room without any averagin... | cardiovascular diseases |
Early gastric cancer. Twenty-eight-year experience. A retrospective study of early gastric cancer (60 patients) was performed to evaluate its diagnosis and treatment. Ninety-five per cent of patients presented with nonspecific gastrointestinal symptoms and 53.3% had been treated for presumed benign disease for up to 48... | nervous system diseases |
Relative risks of left ventricular aneurysmectomy in patients with akinetic scars versus true dyskinetic aneurysms. From 1971 to 1988, 303 patients underwent left ventricular aneurysm resection. We analyzed preoperative and procedure-related variables to ascertain risk factors for surgery. A distinction was made betwee... | cardiovascular diseases |
Fatal or severely disabling cerebral infarction during hospitalization for stroke or transient ischemic attack. Six (1%) of 578 patients admitted for cerebral infarction or transient ischemic attack (TIA) suffered a fatal or severely disabling in-hospital cerebral infarction following a period of stabilization or impro... | nervous system diseases |
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