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Mesial temporal sclerosis: pathogenesis, diagnosis, and management. Mesial temporal sclerosis (MTS) is probably the most common symptomatic pathologic entity--alone or mixed with other pathologic features--for seizures of temporal lobe origin. The pathophysiology of MTS, including any genetic influence, needs clarifica... | general pathological conditions |
Feasibility of reversing benzodiazepine tolerance with flumazenil To examine whether the benzodiazepine antagonist flumazenil can reverse tolerance to benzodiazepines but without precipitating withdrawal seizures, the antiepileptic effect of flumazenil itself and its ability to reverse tolerance at a dose that would le... | nervous system diseases |
Free-tissue transfers for limb salvage utilizing in situ saphenous vein bypass conduit as the inflow. Using vein grafts to bypass sclerotic and occluded arterial segments is a well-established technique in vascular surgery. For infrapopliteal bypass, autogenous veins have better patency rates than synthetic grafts. Alt... | cardiovascular diseases |
Transitional cell carcinoma of the upper urinary tract: prognostic variables and post-operative recurrences. In a retrospective study of 198 patients with transitional cell carcinoma of the upper urinary tract, post-operative recurrences developed as contralateral tumours in 2.5%, in the ureteric stump after conservati... | neoplasms |
Pain on common bile duct injection during ERCP: does it indicate sphincter of Oddi dysfunction? The reproduction of a patient's biliary-type pain upon initial injection of contrast material into the common bile duct during diagnostic ERCP is a dramatic experience for both patient and physician. The significance of this... | nervous system diseases |
The cutaneous manifestations in children with familial Mediterranean fever (recurrent hereditary polyserositis). A six-year study. In a six-year study of 46 children with familial Mediterranean fever (recurrent hereditary polyserositis), 20 children (43 per cent) developed cutaneous manifestations. Ten children had 18 ... | cardiovascular diseases |
Thyroiditis. Acute, subacute, and chronic. Inflammatory diseases of the thyroid are collectively the commonest thyroid disorder. Individually, they range from the rare case of acute bacterial thyroiditis to the other end of the spectrum, the even rarer Riedel's thyroiditis. Relatively common thyroid inflammatory diseas... | general pathological conditions |
Association between extent of colonic mucosal sialomucin change and subsequent local recurrence after curative excision of primary colorectal cancer. Two interrelated studies were carried out to determine whether extent of sialomucin change adjacent to a primary colorectal carcinoma predicted local tumour invasiveness ... | neoplasms |
The increased frequency of cervical dysplasia-neoplasia in women infected with the human immunodeficiency virus is related to the degree of immunosuppression. Cytologic and histologic investigations of the uterine cervix and studies of the lymphocyte functions were performed in human immunodeficiency virus-infected and... | neoplasms |
Primary neoplasms of the hollow organs of the gastrointestinal tract. Staging and follow-up. The number of imaging modalities available to stage and follow-up patients with primary neoplasms of the gastrointestinal (GI) tract continues to increase. Magnetic resonance imaging (MRI), computed tomography (CT), and ultraso... | neoplasms |
Biliary and gut function following shock. The aim of this study was to characterize the alterations in gallbladder and intestinal function after hemorrhagic shock and blood reperfusion in opossums. Animals were subjected to a shock of 30 mm Hg of arterial blood pressure for 60 minutes and resuscitated with blood reinfu... | general pathological conditions |
Resection of the superior vena cava for primary lung cancer: 5 years' survival. We describe a patient with squamous cell carcinoma of the right lung that required a resection of the superior vena cava combined with a tracheal sleeve pneumonectomy. The superior vena cava was totally replaced with a polytetrafluoroethyle... | neoplasms |
Acquired childhood aphasia. Outcome 1 year after onset. The effects of the variables age at onset, cause, severity and bilaterality of lesion, and type of aphasia on course and outcome were investigated in a group of 28 aphasic children. Analysis of spontaneous speech and tests of auditory verbal comprehension were use... | general pathological conditions |
Cancer chemotherapy after solid organ transplantation. To assess how well chemotherapy is tolerated after solid organ transplantation, we reviewed our experience at the Children's Hospital of Pittsburgh with five patients aged 1 to 12 years. Four patients had a liver transplant, indications for which were hepatoblastom... | neoplasms |
Acute epididymitis: why patient and consort must be investigated. In this prospective study of 49 patients under 35 years of age with clinically diagnosed epididymitis, detailed microbiological investigation identified an infective cause in 67%. Chlamydia trachomatis was the commonest agent, present in 25 patients, but... | general pathological conditions |
Characterization of "peak E," a novel amino acid associated with eosinophilia-myalgia syndrome. Epidemiologic studies strongly associate eosinophilia-myalgia syndrome (EMS) with ingestion of tryptophan containing a contaminant ("peak E"). Prior reports have suggested that peak E is the di-tryptophan N alpha-animal of a... | general pathological conditions |
Effects of nisoldipine on myocardial ischemia during exercise and during daily activity. The antiischemic properties of nisoldipine, a dihydropyridine calcium antagonist, were assessed in a multicenter, double-blind, placebo-controlled trial by repeated exercise testing and 72-hour ambulatory electrocardiographic monit... | cardiovascular diseases |
Gaucher's disease complicated by bleeding esophageal varices and colonic infiltration by Gaucher cells. We report a 10-yr-old child with Gaucher's disease who developed upper gastrointestinal bleeding from esophageal varices, as well as hemorrhage from a colonic polyp infiltrated with Gaucher cells. Both the varices an... | general pathological conditions |
Audiological findings following head trauma. Traumatic head injury is the principal cause of death and serious physical disability in adolescents and young adult. Hearing loss is a common sequela of head trauma. The results of pure tone and auditory brain-stem response (ABR) assessment of minor head injury revealed tha... | general pathological conditions |
Retrograde continuous warm blood cardioplegia: a new concept in myocardial protection This report presents the results in our first clinical series of patients receiving continuous warm blood cardioplegia through the coronary sinus. Warm oxygenated blood cardioplegia has certain theoretical advantages, such as continuo... | cardiovascular diseases |
The standardized assessment of argyrophilic nucleolar organizer regions in meningeal tumors. Tissue markers of cellular proliferation have been recently utilized as prognostic indicators in tumors of the central nervous system. Nucleolar organizer regions represent transcriptionally active sites of ribosomal deoxyribon... | neoplasms |
Cancer in the families of children with soft tissue sarcoma. The cancer experience among 754 first-degree relatives (mothers, fathers, and siblings) of a population-based series of 177 children with soft tissue sarcoma is reported. The current study represents an extension of our earlier work in which the authors found... | neoplasms |
Intradural epithelial cyst at the craniovertebral junction. Case report. A case of an intradural epithelial cyst at the craniovertebral junction is reported in a 37-year-old man. The classification of these rare lesions is discussed. | neoplasms |
Epidural morphine for analgesia after caesarean section: a report of 4880 patients This retrospective study was undertaken to assess the efficacy and safety of epidural morphine in providing analgesia following Caesarean section under epidural anaesthesia. The morphine was administered as a single bolus, following deli... | general pathological conditions |
Reappraisal of surgical treatment of traumatic transection of the thoracic aorta. Since Crawford's report in 1973, repair of traumatic transection of the thoracic aorta without shunt or bypass has emerged as a popular technique which simplifies the operation and avoids use of heparin. Growing evidence, however, indicat... | general pathological conditions |
Surgical treatment of a rare congenital anomaly of the vertebral artery: case report and review of the literature. A case of an abnormal loop of the vertebral artery compressing both the cervicomedullary junction and the accessory nerve is reported. The embryological development of the vertebrobasilar system may explai... | nervous system diseases |
Mandibular reconstruction with composite microvascular tissue transfer. Microvascular free tissue transfer has provided a variety of methods of restoring vascularized bone and soft tissue to difficult defects created by tumor resection and trauma. Over 7 years, 26 patients have undergone 28 free flaps for mandibular re... | general pathological conditions |
Pericarditis with tamponade due to cytomegalovirus in the acquired immunodeficiency syndrome. A 35-year-old male homosexual with AIDS presented with headache and fever and was found to have cryptococcal meningitis. During the patient's hospital course, his hemodynamic status deteriorated as a result of pericardial tamp... | cardiovascular diseases |
Examination by logistic regression modelling of the variables which increase the relative risk of elderly women falling compared to elderly men. In a community based, prospective study to determine risk factors for falls, 465 women and 296 men 70 years and over were followed for 1 year and 507 falls were documented. A ... | nervous system diseases |
Late cholangitis after successful surgical repair of biliary atresia. Bacterial cholangitis is a frequent complication of successful surgical repair of biliary atresia, occurring in 93% of patients before the age of 1 year, but thought to be rare after 2 years of age. Among 76 children free of jaundice more than 5 year... | general pathological conditions |
A phosphatase activity present in peripheral blood myeloid cells of chronic myelogenous leukemia patients but not normal individuals alters nuclear protein binding to transcriptional enhancers of interferon-inducible genes. Cytoplasmic protein from peripheral blood myeloid cells of chronic myelogenous leukemia (CML) pa... | neoplasms |
Ultrasonographic detection of the second-trimester fetus with trisomy 18 and trisomy 21. Biparietal diameter/femur length ratio and nuchal thickness were found to be sensitive indicators for the prenatal detection of trisomy 18 and trisomy 21. A biparietal diameter/femur length ratio greater than 1.5 SD above the contr... | general pathological conditions |
Fatal embolization of intestinal contents through a duodenocaval fistula. Embolization of intestinal contents to the lung is an exceedingly rare event, which to our knowledge, has never been reported as a cause of death. Equally rare is duodenocaval fistula resulting from a penetrating duodenal peptic ulcer. We present... | general pathological conditions |
Poisoning with equine phenylbutazone in a racetrack worker. Phenylbutazone is a potent nonsteroidal, anti-inflammatory drug often used by veterinarians to treat racetrack animals. Its use in human beings is limited because of significant adverse effects and the availability of newer, safer drugs. We report the case of ... | general pathological conditions |
Synaptic transmission in human neocortex removed for treatment of intractable epilepsy in children. Synaptic transmission to pyramidal cells was studied in slices of neocortex resected from infants and children (n = 10, age 8 months to 13 years) undergoing surgical treatment for intractable epilepsy. Most specimens wer... | nervous system diseases |
Effect of left ventricular aneurysm on risk of sudden and nonsudden cardiac death. Although left ventricular (LV) aneurysm is associated with increased mortality, its independent prognostic significance is controversial. To determine the effect of LV aneurysm on risk, 121 patients with healed myocardial infarction (MI)... | general pathological conditions |
Improvement of septic syndrome after administration of recombinant human growth hormone (rhGH)? Twenty patients with generalized sepsis were studied prospectively to evaluate the effects of recombinant human growth hormone (rhGH) administration. Five patients had developed sepsis after major abdominal surgery, 15 patie... | general pathological conditions |
Bactericidal effect of doxycycline associated with lysosomotropic agents on Coxiella burnetii in P388D1 cells. There is no consistently reliable treatment for endocarditis resulting from chronic Coxiella burnetii infection, the causative agent of Q fever. Although certain antibiotics are recommended on the basis of the... | neoplasms |
Genital human papillomavirus infection Human papillomavirus is one of the most common causes of sexually transmitted diseases. In the past ten years, 60 different types of papillomavirus have been identified. Although the virus often causes asymptomatic genital infection, it has been strongly associated with lower geni... | neoplasms |
Familial incidence of Paget's disease and secondary osteogenic sarcoma. A report of three cases from a single family. This report describes a family of three siblings with a long history of polyostotic Paget's disease. Because of the severe osseous involvement with Paget's disease, all three patients had problems that ... | neoplasms |
Transesophageal echocardiographic features of normal and dysfunctioning bioprosthetic valves. Transesophageal and transthoracic echocardiography and color flow Doppler were performed in patients with 42 normal and 20 dysfunctioning bioprosthetic mitral and aortic valves. Transesophageal echocardiography was superior to... | general pathological conditions |
Recurrent herpes gestationis with postpartum flare: a case report. A case of herpes gestationis recurring in each pregnancy, with a postpartum flare-up in the last pregnancy, is described. The diagnosis was confirmed by skin biopsy. The first pregnancy ended in a term stillbirth, but there were favorable outcomes in fo... | general pathological conditions |
Transvaginal approach for repair of rectovaginal fistulae complicating Crohn's disease. The management of rectovaginal fistulae complicating Crohn's disease is difficult and often unsatisfactory. Between December 1983 and November 1988, 13 patients with Crohn's disease underwent repair of rectovaginal fistulae via a tr... | general pathological conditions |
Assessment of experimental pericardial effusion using nuclear magnetic resonance imaging techniques. An experimental canine model of pericardial effusion was designed to validate previous clinical nuclear magnetic resonance imaging (NMR) studies. Saline (n = 7), serum (n = 4), blood (10% hematocrit [n = 5]; 20% hematoc... | cardiovascular diseases |
Assessment of the components of observed chronic pain behavior: the Checklist for Interpersonal Pain Behavior (CHIP). This article describes the development of the Checklist for Interpersonal Pain Behavior (CHIP), an observation scale which assesses overt pain behavior. The study is an extension of an earlier study in ... | nervous system diseases |
Aortobronchial fistula after an aortic operation. A 71-year-old man with a postoperative aortobronchial fistula was successfully treated. The fistula occurred between the left lower lobe and the descending thoracic aorta, to which a distal anastomosis of a temporary bypass graft had been placed during thoracic aortic a... | general pathological conditions |
Lymphocyte subset distribution after radiation therapy for cancer of the uterine cervix. Possible prognostic implications and correlation with disease course. An analysis of lymphocyte subpopulations was done in patients with cancer of the uterine cervix before and at different intervals after the commencement of radia... | neoplasms |
Facilitating clinical trials. The expanding role of the nurse. Clinical trials are becoming increasingly difficult to carry out in the face of a changing health care delivery system. The reluctance of third party payers to reimburse for experimental therapy and the growing practice of providers to limit resources alloc... | neoplasms |
Effect of plasmapheresis on serum and CSF autoantibody levels in CNS paraneoplastic syndromes. We compared the effect of plasmapheresis on antineuronal autoantibody titers in the serum and CSF of 3 patients with CNS paraneoplastic syndromes. Plasmapheresis reduced the serum autoantibody titer to 20% of the initial leve... | neoplasms |
Chronic hypomagnesemia caused by cisplatin: effect of calcitriol. A group of six patients with hypomagnesemia (serum magnesium less than or equal to 0.5 mmol/L), previously given treatment with cisplatin for ovarian or testicular cancer, received calcitriol at a dose of 0.5 to 1.0 microgram/day for a period of 4 weeks ... | general pathological conditions |
The detubularized right colonic segment as urinary reservoir: evolution of technique for continent diversion. Continent diversion of urine via a cecal-right colonic reservoir has been performed at our university hospital since 1977. Several modifications of surgical technique have been devised to prevent problems of ur... | general pathological conditions |
'Cystic papilloma' in humans? Demonstration of human papillomavirus in plantar epidermoid cysts. Fourteen cases of plantar epidermoid cyst were studied immunohistochemically and five of them were also studied electron microscopically for the presence of human papillomavirus. In eleven cases, the test results were posit... | neoplasms |
Clinoidal meningiomas. Anterior clinoidal meningiomas are frequently grouped with suprasellar or sphenoid ridge meningiomas, masking their notorious association with a high mortality and morbidity rate, failure of total removal, and recurrence. To avoid injury to encased cerebral vessels, most surgeons are content with... | neoplasms |
Prognostic importance of delayed Q-wave evolution 3 to 24 hours after initiation of thrombolytic therapy for acute myocardial infarction. The timing of Q-wave evolution and its prognostic significance was studied in 201 patients who received thrombolytic therapy for a first acute myocardial infarction (AMI). One hundre... | cardiovascular diseases |
Aggressive surgical intervention in N2 non-small cell cancer of the lung. An aggressive attitude toward surgical treatment was taken in patients with N2 non-small cell lung cancer in the past 10 years. Computed tomographic scanning was employed in the diagnosis of N2 disease, and had a true-positive rate of 57%. Among ... | neoplasms |
Prospective study of the frequency and size distribution of polyps missed by colonoscopy. An important determinant in interpreting the results of colorectal polyp chemoprevention trials is the rate of polyps missed during colonscopic examination. We prospectively examined 90 patients by tandem colonoscopy performed by ... | neoplasms |
Bleeding time prolongation with streptokinase and its reduction with 1-desamino-8-D-arginine vasopressin. The mechanism by which treatment with thrombolytic agents causes bleeding is not known. Recently, frequency of bleeding events has been shown to correlate with bleeding time, particularly in individuals treated wit... | general pathological conditions |
Hyperfunctioning metastatic follicular thyroid carcinoma in Pendred's syndrome. A 66-year-old woman with Pendred's syndrome underwent a partial thyroidectomy when she was 17 years old. At the age of 52 years, she had a second thyroid operation because of hyperthyroidism due to a toxic multinodular goiter with a mediast... | general pathological conditions |
Visual evoked potential monitoring of optic nerve function during surgery. A study was made with intra-operative flash--visual evoked potentials (VEP) monitored using a fibre-optic/contact lens photo stimulator in 57 patients undergoing intra-orbital surgical procedures with potential risk to the optic nerve. The VEPs ... | general pathological conditions |
A protocol for the investigation of pregnancy loss. A protocol for the evaluation of pregnancy loss should include a maternal history, dysmorphic examination of the fetus or abortus, photographs, autopsy, chromosome studies (in most cases), and radiographic or xeroradiographic studies. Selected cases with suspected asc... | general pathological conditions |
Intraoperative bronchial aspiration of ruptured pulmonary hydatid cysts. Ruptured pulmonary hydatid cysts are seen clinically and radiologically as persistent cavitary lesions of the lung. Bronchi opening into the pericyst cavity allow for discharge of fluid matter but not the escape of solid remnants of the collapsed ... | general pathological conditions |
Changes in quality of care for five diseases measured by implicit review, 1981 to 1986 We measured quality of care before and after implementation of the prospective payment system. We developed a structured implicit review form and applied it to a sample of 1366 Medicare patients with congestive heart failure, acute m... | cardiovascular diseases |
Preoperative endoscopic diagnosis of fibroepithelial polyp of the renal pelvis: a case report and review of the literature. Benign fibroepithelial polyps of the renal pelvis are rare, with only 9 cases described previously in the literature. We report an additional case and suggest how nephrectomy may be avoided. | neoplasms |
Subaortic obstruction: intraoperative echocardiography as an adjunct to operation. Fourteen patients undergoing operation for subaortic obstruction (membranous obstruction in 11 patients, tunnel obstruction in 2 patients, obstruction due to reduplicated mitral valve tissue in 1 patient) were evaluated by intraoperative... | cardiovascular diseases |
Prognostic importance of the serum magnesium concentration in patients with congestive heart failure. Magnesium abnormalities are common in patients with congestive heart failure but the clinical and prognostic significance of an abnormal serum magnesium concentration in this disorder has not been investigated. Therefo... | cardiovascular diseases |
Neuromesenchymal hamartoma of the small bowel. We present the case of a long small bowel stricture with pathological features similar to those described as "neuromuscular and vascular hamartoma," showing in addition extensive fatty submucosal infiltration and fibrous intramural nodules. In the controversy about the nat... | neoplasms |
Massive histamine release in a patient with systemic mastocytosis. We have measured plasma histamine concentrations, systemic vascular resistance, cardiac output and arterial pressure during laparotomy in a patient with systemic mastocytosis. The patient developed vasodilation and hypotension during surgery, associated... | general pathological conditions |
Pulmonary vascular steal in chronic thromboembolic pulmonary hypertension. After pulmonary thromboendarterectomy, performed for relief of chronic thromboembolic pulmonary hypertension, perfusion lung scans have frequently disclosed new perfusion defects in segments served by undissected pulmonary arteries. Our hypothes... | general pathological conditions |
Localised endosteal bone lysis in relation to the femoral components of cemented total hip arthroplasties. Four cases are described of localised endosteal bone lysis in the femur occurring in association with cemented femoral components that were not obviously 'loose' radiologically. In each, the area of lysis was show... | general pathological conditions |
Causes of death in the elderly and their changing pattern in Hisayama, a Japanese community. Results from a long-term and autopsy-based study. The causes of death for the elderly were prospectively studied in Hisayama, Japan, a rural community. We compared 1,621 subjects, aged 40 years or over, recruited in 1961, and 2... | nervous system diseases |
Colonic glycoproteins in monozygotic twins with inflammatory bowel disease. Colonic glycoprotein composition was evaluated in monozygotic twins with inflammatory bowel disease using ion-exchange chromatography. Fifty-three individuals, 12 pairs and 1 single twin with ulcerative colitis and 14 pairs with Crohn's disease... | digestive system diseases |
Spinal cord compression from a thoracic paraganglioma: case report. A 34-year-old man with a 4-month history of midthoracic back pain sought treatment for a recent onset of lower extremity paresthesia and stiffness. A myelogram and computed tomographic myelogram disclosed an extradural block at the level of the 8th tho... | neoplasms |
Endothelium-derived relaxing factor inhibits hypoxic pulmonary vasoconstriction in rats. The hypothesis that endothelium-derived relaxing factor (EDRF) modulates hypoxic pulmonary vasoconstriction (HPV) was tested in isolated, blood-perfused rat lungs ventilated with gas mixtures of 21% O2-5% CO2-74% N2 (normoxia) or o... | general pathological conditions |
The transoral approach for the management of intradural lesions at the craniovertebral junction: review of 7 cases. The main difficulty in dealing with intradural lesions located ventrally in the region of the craniovertebral junction (CVJ) is related to their relative inaccessibility. Posterolateral approaches involve... | nervous system diseases |
Intra-abdominal abscesses in Crohn's disease. We reviewed 22 patients who had intra-abdominal abscesses secondary to Crohn's disease. A total of 29 abscesses were discovered. These included superficial and deep intraperitoneal as well as pelvic and retroperitoneal abscesses. Diagnosis was aided by ultrasound and comput... | digestive system diseases |
Intraluminal crystalloids in struma ovarii. Immunohistochemical, DNA flow cytometric, and ultrastructural study. We recently encountered a unique case of follicular variant of papillary carcinoma arising in struma ovarii that contained numerous intrafollicular crystalloids. There was no evidence of capsular or vascular... | neoplasms |
A possible role for antiphospholipid antibodies in acquired cardiac valve deformity. We studied the frequency of antiphospholipid antibodies (aPL) in patients undergoing cardiac valve replacement, and present the results in the context of the pathology of the valve lesions. Forty-eight consecutive patients undergoing v... | cardiovascular diseases |
The natural history of colorectal cancer. Opportunities for intervention. There is now a better understanding of the natural history of colorectal cancer, which has provided a basis for intervention to influence outcome. The possible interventions include earlier detection of colorectal cancer, removal of premalignant ... | neoplasms |
Proximal tubular alpha 2-adrenoceptor density in the spontaneously hypertensive rat. In the kidney of the spontaneously hypertensive rat (SHR), alpha 2-adrenoceptors are increased and may be related to hypertension. We measured alpha 2-adrenoceptor density and characteristics in a proximal tubule suspension with the al... | cardiovascular diseases |
Radical prostatectomy versus expectant primary treatment in stages I and II prostatic cancer. A fifteen-year follow-up. A fifteen-year follow-up of a prospective, randomized study comparing placebo with radical prostatectomy as the primary treatment of early prostatic cancer is presented. A total of 111 patients with c... | neoplasms |
Bretylium tosylate versus lidocaine in experimental cardiac arrest Bretylium tosylate has been shown effective in the treatment of ventricular fibrillation and in the prevention of its recurrence. However, lidocaine is generally preferred because bretylium could have adverse hemodynamic effects related to its antiadren... | general pathological conditions |
The pituitary-adrenocortical system of neonatal rats is responsive to stress throughout development in a time-dependent and stressor-specific fashion. The responsiveness of the neonatal hypothalamus-pituitary-adrenal (HPA) axis to stress has been thought to be impaired or diminished during the first 2 weeks of life. Al... | general pathological conditions |
The hands in alcoholic liver disease. Chronic liver disease is frequently associated with a hyperdynamic circulation, with warm hands and capillary pulsations. In our experience, however, a significant number of patients with alcoholic liver disease complain of cold hands. In this study, we have investigated the presen... | digestive system diseases |
Genetic mapping of new DNA probes at Xq27 defines a strategy for DNA studies in the fragile X syndrome. The fragile X syndrome is the most common cause of familial mental retardation and is characterized by a fragile site at the end of the long arm of the X chromosome. The unusual genetics and cytogenetics of this X-li... | nervous system diseases |
Quantitative evaluation of hypnotically suggested hyperaesthesia and analgesia by painful laser stimulation. The ability to reduce both clinically and experimentally induced pain by hypnotic suggestion of analgesia is well known. However, the nature of hypnotic analgesia still remains uncertain. Attempts to demonstrate... | nervous system diseases |
Bilateral sudden deafness and acute acquired toxoplasmosis. An 18-year-old woman, while suffering from acute acquired toxoplasmosis, experienced sudden deafness and a total loss of vestibular function first in the right ear and three months later also in the left. Following treatment with sulphadiazine and pyrimethamin... | general pathological conditions |
Landau-Kleffner syndrome: a pharmacologic study of five cases. Five children with Landau-Kleffner syndrome (epilepsy, acquired aphasia, and continuous spike-wave discharges during sleep), were treated with antiepileptic drugs (AEDs), sleep-modifying drugs, and corticosteroids. The pharmacologic profiles differed from t... | general pathological conditions |
Cystic tumors of the pancreas. New clinical, radiologic, and pathologic observations in 67 patients. Within a 12-year period we treated 67 patients (49 women, 18 men; mean age, 61 years) with cystic neoplasms of the pancreas, including 18 serous cystic adenomas, 15 benign mucinous cystic neoplasms, 27 mucinous cystaden... | neoplasms |
Haemostatic changes during continuous oestradiol-progestogen treatment of postmenopausal women. To identify changes in haemostatic balance during continuous oestradiol-progestogen treatment, 60 postmenopausal women with climacteric complaints, mean age 55.4 years (range 44-68) were randomly allocated to receive one of ... | cardiovascular diseases |
Posttraumatic cortical blindness: are we missing the diagnosis in children? A potential etiology of anxiety and agitation in the posthead trauma patient is cortical blindness. Cortical blindness can be seen after both mild and severe head trauma. Early recognition and understanding of this syndrome can lead to a decrea... | general pathological conditions |
Correlation of the structure of the transmembrane domain of the neu oncogene-encoded p185 protein with its function. The human homologue of the neu oncogene is frequently found in human tumors. Certain amino acid substitutions at position 664 in the transmembrane domain of the neu oncogene-encoded p185 protein product ... | neoplasms |
Lipoprotein (a) and coronary heart disease: a prospective case-control study in a general population sample of middle aged men. OBJECTIVE--To examine the association between the serum lipoprotein (a) concentration and subsequent coronary heart disease. DESIGN--Prospective case-control study based on a six year follow u... | cardiovascular diseases |
Gastroduodenal mucosa in uraemia: endoscopic and histological correlation and prevalence of helicobacter-like organisms. This study aimed to determine the prevalence of endoscopic and histological gastroduodenitis as well as helicobacter-like organisms in patients with end stage renal failure undergoing maintenance dia... | digestive system diseases |
The human costs of cancer and the response of the National Cancer Program. The three foundations of the National Cancer Program are basic research, clinical trials (in prevention and treatment), and cancer centers. These foundations have supported a great deal of progress against cancer over the past 20 years. Neverthe... | neoplasms |
Post-extrasystolic potentiation without a compensatory pause in normal and diseased hearts. Variables derived from left ventricular volume were used to study post-extrasystolic potentiation. Left ventriculograms were obtained from 11 healthy individuals and 49 patients with coronary heart disease (30 with a previous my... | cardiovascular diseases |
Emergency center ultrasonography in the evaluation of hemoperitoneum: a prospective study. The reliability of ultrasonographic detection (US) of hemoperitoneum in blunt abdominal trauma was evaluated in a prospective study of 72 patients. Independent of the examiner, sensitivity, specificity, and accuracy were, respect... | general pathological conditions |
Association of Escherichia coli HEp-2 adherence patterns with type and duration of diarrhoea. 373 (59%) out of 636 faecal specimens obtained during the first 2 years of life of 72 Mexican children yielded adherent Escherichia coli (HEp-2 cells). Strains with localised adherence were significantly associated with acute ... | digestive system diseases |
Outcome of hepatitis B virus infection in homosexual men and its relation to prior human immunodeficiency virus infection. To investigate the effect of human immunodeficiency virus type 1 (HIV-1) infection on subsequent hepatitis B virus (HBV) infection, HIV antibody was sought in homosexual men who developed HBV infec... | digestive system diseases |
Coronary artery bypass operation in dialysis patients. To analyze the short- and long-term morbidity and mortality among maintenance dialysis patients who have undergone coronary artery bypass operations, we identified 25 such patients at the Mayo Clinic and three recently published large single-center studies that pro... | general pathological conditions |
Selective vasopressin inhibition in rats with heart failure decreases afterload and results in venodilatation. The hemodynamic effects of selective inhibition of arginine vasopressin (AVP) with a V1 antagonist, (CH2)5yreAVPa CL-1-4A, were studied in normal rats (n = 17) and in rats 4 weeks after coronary artery ligatio... | cardiovascular diseases |
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