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Prognosis of patients with ventricular tachycardia or fibrillation and a normal electrophysiologic study. The outcome of 26 patients with sustained ventricular tachycardia (n = 16) or ventricular fibrillation (n = 10) and no inducible ventricular tachycardia (less than or equal to 10 beats) by baseline programmed stimu... | general pathological conditions |
Granulomatous vasculitis in Crohn's disease [published erratum appears in Gastroenterology 1991 Aug;101(2):595] This study investigated a possible vascular origin for granulomas in Crohn's disease. Twenty-four consecutive resected specimens of small and large intestinal Crohn's disease were preserved by arterial perfus... | digestive system diseases |
Epiretinal membrane contracture associated with macular prolapse. We treated two patients with annular epiretinal membranes that produced unusual macular morphologic characteristics. Contracture of the membranes caused herniation of macular tissue through a hole in the center of the membrane. The membranes were removed... | general pathological conditions |
The "numb cheek-limp lower lid" syndrome. A patient developed isolated numbness, 1st confined to the lateral nose and upper lip, but later involving the cheek, lower lip, upper gingiva, and the palate. This numbness was later associated with paresis of the muscles of the upper lip and angle of the mouth and with ipsila... | nervous system diseases |
Use of a computerized closed-loop sodium nitroprusside titration system for antihypertensive treatment after open heart surgery. This study evaluates the clinical applicability of administering sodium nitroprusside by a closed-loop titration system compared with a manually adjusted system. The mean arterial pressure (M... | general pathological conditions |
Intraperitoneal yttrium-90-labeled monoclonal antibody in ovarian cancer From March 1987 to March 1988, a phase I to II study was carried out in 25 patients with ovarian cancer. They received escalating doses of intraperitoneally (IP) administered yttrium-90 (Y-90)-labeled monoclonal antibody, HMFG1, against a tumor ce... | neoplasms |
Excipients in valproic acid syrup may cause diarrhea: a case report. A 5-year-old child receiving valproic acid syrup for seizure control developed diarrhea probably from the excipient ingredients. Each 5 mL of valproic acid syrup contains sucrose 3 g, glycerin 0.75 g, and sorbitol 0.75 g, providing daily amounts of 36... | nervous system diseases |
Middle cerebral artery strokes causing homonymous hemianopia: positron emission tomography. Eight patients were evaluated with 18F-fluorodeoxyglucose positron emission tomography between 3 and 30 days after isolated stroke involving the middle cerebral artery territory that caused homonymous hemianopia. Diffuse hypomet... | general pathological conditions |
Anti-Kell in pregnancy. A review of data on haemolytic disease of the newborn (HDN) collected in Newcastle upon Tyne over 25 years revealed 194 pregnancies in which anti-Kell was the only antibody detected. Sixteen affected babies were born. None was hydropic, three had very severe disease but all survived. There were ... | general pathological conditions |
Malignant potential of juvenile polyposis coli. Report of a case and review of the literature. Juvenile polyps of the colon and rectum traditionally have been viewed as being benign inflammatory or harmartomatous lesions without potential for malignant change. The authors report a case of adenocarcinoma developing in a... | digestive system diseases |
Urinary excretion of Tamm-Horsfall protein in women with recurrent urinary tract infections. Since MS-fimbriated bacteria adhere to Tamm-Horsfall protein, it has been suggested that Tamm-Horsfall protein may trap urinary pathogens and prevent them from colonizing the mucosal surfaces of the urinary tract. To test the h... | general pathological conditions |
Premalignant lesions: role of antioxidant vitamins and beta-carotene in risk reduction and prevention of malignant transformation. Epidemiological studies have shown that diets rich in one or more antioxidant nutrients may reduce the risk of cancers of the lung, uterine cervix, mouth, and gastrointestinal tract. Study ... | neoplasms |
The supraspinal anxiolytic effect of baclofen for spasticity reduction. Recent studies in the psychiatric literature indicate that baclofen has an anxiolytic action in certain psychopathologic conditions. Clinical observation has shown that manifestations of spasticity are increased in anxious individuals, implicating ... | nervous system diseases |
Human immunodeficiency virus associated with thrombotic thrombocytopenic purpura: successful treatment with zidovudine. Thrombocytopenia associated with human immunodeficiency virus (HIV) is well described, and two recent reports show a beneficial effect with the antiretroviral agent zidovudine (ZDV). HIV-associated th... | general pathological conditions |
Comparative studies of DU-PAN-2, carcinoembryonic antigen, and CA19-9 in the serum and bile of patients with pancreatic and biliary tract diseases: evaluation of the influence of obstructive jaundice. The levels of DU-PAN-2 antigen, carcinoembryonic antigen, and CA19-9 in serum and bile of patients with pancreatic and ... | digestive system diseases |
Effects of H2-receptor blockers on response of cerebral blood flow to normocapnic hypoxia. Cimetidine blunts the increase in cerebral blood flow (CBF) normally observed during hypoxia. It is important, therefore, to know whether other H2-blockers also affect the cerebral circulation adaptation to hypoxia. Cerebral bloo... | general pathological conditions |
HLA class II antigens and DNA restriction fragment length polymorphism in myasthenia gravis in Japan. Human leukocyte phenotypes and genes in the HLA class II regions were studied in 46 Japanese patients with myasthenia gravis. When the HLA phenotypes of the patients with myasthenia gravis were compared with the contro... | nervous system diseases |
The relationship of Papanicolaou testing and contacts with the medical care system to stage at diagnosis of cervical cancer. The relationship of Papanicolaou (Pap) testing and physician visits to stage at diagnosis of cervical cancer was assessed by interviews with 149 women with invasive cervical cancer and 214 women ... | neoplasms |
Dystonia in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy. Adult-onset dystonia-parkinsonism is a syndrome in search of a pathology. We therefore reviewed the literature on dystonic manifestations in autopsy-proven cases of multiple system atrophy (MSA), progressive supranuclear palsy... | general pathological conditions |
Cell-to-cell communication and the control of growth. Growth of transformed cells is inhibited by cell-to-cell communication with normal cells. This communication is regulated by certain oncogenes that alone or in cooperation can block the communication. | neoplasms |
A plasma protease which is expressed during supramaximal stimulation causes in vitro subcellular redistribution of lysosomal enzymes in rat exocrine pancreas. The complex events by which digestive enzyme zymogens and lysosomal hydrolases are segregated from each other and differentially transported to their respective ... | digestive system diseases |
On the inheritance of abdominal aortic aneurysm. To determine the mode of inheritance of abdominal aortic aneurysm, data on first-degree relatives of 91 probands were collected. Results of segregation analysis performed on these data are reported. Many models, including nongenetic and genetic models, were compared usin... | cardiovascular diseases |
Neurological phenomena during emergence from enflurane or isoflurane anaesthesia. During emergence from anaesthesia, transient neurological signs that would usually be considered pathological may appear. The objective of this randomized, patient (n = 30) and observer-blinded study was to compare prospectively the incid... | general pathological conditions |
Successful conservative management of primary nonmetastatic cervical choriocarcinoma. Primary cervical choriocarcinoma is a rare disease; since 1915 only about 60 cases have been published. The case presented here can be defined as primary cervical choriocarcinoma since it fulfills all the criteria delineated previousl... | neoplasms |
Hepatic tumors: signal enhancement at Doppler US after intravenous injection of a contrast agent. Experiments were carried out to detect and establish the origin of Doppler and echo signal enhancement in small vessels of the systemic circulation and of tumors after intravenous injection of a contrast agent. Eight woodc... | neoplasms |
Traumatic rupture of the aorta--critical decisions for trauma surgeons. The diagnosis and initial stabilization of patients with traumatic rupture of the aorta (TRA) is performed by trauma surgeons. The resuscitations of 54 TRA patients at a Level I trauma center are reviewed. Although the survival of patients who unde... | general pathological conditions |
Stenosis of the sphincter of Oddi. "Stenosing papillitis" is a descriptive term for an anatomic deformity of the papilla of Vater that is characterized by narrowing of the lower end of the bile duct and the proximal end of the duct of Wirsung. The defect is secondary to inflammation and fibrosis from the chronic passag... | digestive system diseases |
A randomized trial comparing two methods of cold knife conization with laser conization. In a randomized study, 62 women were submitted to cold knife conization with application of Sturmdorf sutures, 60 to cold knife conization without sutures, and 61 to laser conization. Early hemorrhage occurred in 1.6, 13.3, and 6.6... | neoplasms |
Emergent signs of cancer. Recognizing them early in the office or ER. Primary care physicians have a crucial role in recognition of potentially emergent conditions in patients with known or suspected cancer. This task presents a significant challenge because the initial manifestations of these conditions are usually no... | cardiovascular diseases |
The cutaneous manifestations in children with familial Mediterranean fever (recurrent hereditary polyserositis). A six-year study. In a six-year study of 46 children with familial Mediterranean fever (recurrent hereditary polyserositis), 20 children (43 per cent) developed cutaneous manifestations. Ten children had 18 ... | general pathological conditions |
Pain experiences of intensive care unit patients. The purpose of this study was to describe various dimensions of the pain experiences of intensive care unit (ICU) patients. A purposive, primarily surgical sample of 24 ICU patients from two hospitals was interviewed after transfer from ICU. All but one patient remember... | general pathological conditions |
Impact of field-transmitted electrocardiography on time to in-hospital thrombolytic therapy in acute myocardial infarction. To assess the impact of a field-transmitted electrocardiogram (ECG) on patients with possible acute myocardial infarction, randomized and open trials were performed with a portable electrocardiogr... | cardiovascular diseases |
Esophageal involvement in pemphigus vulgaris: a clinical, histologic, and immunopathologic study. Eleven newly diagnosed patients and one patient with pemphigus vulgaris who relapsed underwent endoscopy of the upper gastrointestinal tract. Three patients had blisters or erosions and two had longitudinal lines of erythe... | digestive system diseases |
Estrogen receptor localization in normal and neoplastic epithelium of the uterine cervix. To investigate the estrogen receptor (ER) status of cells during carcinogenesis of the uterine cervix, the immunohistochemical reactivity for a monoclonal anti-ER antibody (H 222) was studied in 26 normal cervical specimens, 21 ca... | neoplasms |
Cardiovascular risk factor clustering and ratio of total cholesterol to high-density lipoprotein cholesterol in angiographically documented coronary artery disease. High levels of cardiac risk factors tend to cluster together and act synergistically. To develop a suitable and practical marker for clustering, we evaluat... | cardiovascular diseases |
Alpha 1-antitrypsin granules in the liver--always important? We have studied the clinical histories and liver biopsy findings in 1951 consecutive adult patients with suspected chronic liver disease, and in four known PiZ-homozygous alpha 1-antitrypsin-deficient patients with emphysema (candidates for lung transplant) a... | general pathological conditions |
Imidazole salicylate versus piroxicam in the treatment of arthrosis in elderly patients. A double-blind clinical and endoscopic trial. The clinical efficacy and gastroduodenal tolerability of imidazole salicylate (imidazole 2-hydroxybenzoate, ITF 182), a new synthetic drug with an anti-inflammatory action, was evaluate... | digestive system diseases |
Immunoreactivity and receptor expression of insulinlike growth factor I and insulin in human adrenal tumors. An immunohistochemical study of 94 cases. Using immunoperoxidase methods, 94 human adrenal tumors were examined for evidence of immunoreactivity and receptor expression of insulinlike growth factor I (IGF-I) and... | neoplasms |
Olfactory identification deficits in HIV infection. OBJECTIVE: Impaired odor identification is described in a number of CNS disorders, and human immunodeficiency virus (HIV) infects the CNS in a large percentage of patients. To evaluate whether impaired olfaction may indicate CNS disease, the authors measured odor iden... | nervous system diseases |
A monoclonal antibody against the CD18 leukocyte adhesion molecule prevents indomethacin-induced gastric damage in the rabbit. The role of leukocyte adherence in the mechanism of gastropathy induced by nonsteroidal antiinflammatory drugs was investigated using a rabbit model. Gastric damage was induced by intragastric ... | digestive system diseases |
Primary chemotherapy with or without radiation therapy and/or surgery for children with localized sarcoma of the bladder, prostate, vagina, uterus, and cervix. A comparison of the results in Intergroup Rhabdomyosarcoma Studies I and II. A major objective of the second Intergroup Rhabdomyosarcoma Study (IRS-II) (1978 to... | neoplasms |
Maple syrup urine disease caused by a partial deletion in the inner E2 core domain of the branched chain alpha-keto acid dehydrogenase complex due to aberrant splicing. A single base deletion at a 5'-splice donor site of an intron of the E2 gene disrupts the consensus sequence in this region. We have studied the molecu... | nervous system diseases |
Rupture of atheromatous plaque as a cause of thrombotic occlusion of stenotic internal carotid artery. We analyzed the clinical profiles and autopsy findings of five patients who died shortly after developing cerebral infarction following thrombotic occlusion of the internal carotid artery. In all five cases, thromboti... | general pathological conditions |
Familial multiple desmoplastic trichoepitheliomas. A kindred with familial multiple desmoplastic trichoepitheliomas is described. Desmoplastic trichoepitheliomas should be added to the group of lesions that indicate an inherited pattern when they occur as multiple primary tumors. The implications for nosologic status a... | neoplasms |
Percutaneous excimer laser coronary angioplasty. To determine the efficacy of percutaneous excimer laser coronary angioplasty as an adjunct or alternative to conventional balloon angioplasty, 55 patients were studied in a multicenter trial. These patients underwent the procedure using a modification of conventional bal... | cardiovascular diseases |
Transbronchial biopsies in children after heart-lung transplantation. Sixty transbronchial biopsies have been performed in eight children after heart-lung transplantation. The selection of fiber-optic bronchoscope or a small (4 mm; 30 cm) rigid bronchoscope was made according to the size of endotracheal tube required a... | cardiovascular diseases |
Familial Creutzfeldt-Jakob disease without periodic EEG activity. Four members of a kindred with Creutzfeldt-Jakob disease are reported, in whom myoclonus did not develop and in whom serial electroencephalograms performed late in their illness failed to show periodic sharp wave complexes. Otherwise, the patients' disea... | nervous system diseases |
Laparoscopic cholecystectomy. With more than 500,000 cholecystectomies performed per year, great interest has developed in laparoscopic cholecystectomy. The procedure offers the patient reduced hospital stay, faster return to work, less pain, and improved cosmetic results. In September 1988, we developed a technique of... | digestive system diseases |
Lobulated intradermal nevus. Report of three cases. We report the cases of three patients with lobulated intradermal nevi. Biopsy specimens showed similar findings, that is, fatty infiltration within nests of nevus cells, neuroid differentiation of nevus cells, and dermal fibrosis. Our cases probably represent an unusu... | general pathological conditions |
Syncytial giant-cell hepatitis. Sporadic hepatitis with distinctive pathological features, a severe clinical course, and paramyxoviral features. BACKGROUND AND METHODS. We describe a new form of hepatitis, occurring in 10 patients over a period of six years, characterized clinically by manifestations of severe hepatiti... | digestive system diseases |
Axillary subclavian vein thrombosis. Changing patterns of etiology, diagnostic, and therapeutic modalities. Fifty-two patients with axillary-subclavian vein thrombosis were treated in the last 10 years and were available for follow-up for at least 1 year. Eighteen of these were treated in the first 5 years, Group A, an... | cardiovascular diseases |
Results of treating ductal carcinoma in situ of the breast with conservative surgery and radiation therapy. To determine the frequency, pattern, and time course of tumor recurrence in the breast, the outcome of 38 women with ductal carcinoma in situ (DCIS) treated with conservative surgery and radiation therapy between... | neoplasms |
Threat of unemployment and cardiovascular risk factors: longitudinal study of quality of sleep and serum cholesterol concentrations in men threatened with redundancy. OBJECTIVE--To assess whether the threat of unemployment affects risk factors for cardiovascular disease. DESIGN--Longitudinal study of a cohort of middle... | cardiovascular diseases |
The role of bacteria in pigment gallstone disease. One hundred ten of nine hundred sixty consecutive patients who underwent surgery for gallstones (GS) had pigment stones (PS) (11.45%). Fifty brown PSs contained calcium bilirubinate, small amounts of cholesterol, and always calcium palmitate, were usually found in the ... | digestive system diseases |
Unusual haemostasis for an unusual tumour. Catastrophic bleeding from a tactile neurofibroma affecting the thoracic vertebrae. Case report. The symptomatology of a typical acute descending thoracic aorta dissection was imitated by profuse haemorrhage caused by a benign tumour composed almost exclusively of Wagner-Meiss... | general pathological conditions |
Glaucoma triple procedures: efficacy of intraocular pressure control and visual outcome. Sixty-three glaucoma triple surgeries [combined trabeculectomy, extracapsular cataract extraction (ECCE), and posterior-chamber intraocular lens (PC-IOL) implantation] were reviewed. Intraocular pressure (IOP) was controlled satisf... | general pathological conditions |
Intestinal permeability in patients with chronic urticaria-angioedema with and without arthralgia. We evaluated the clinical response to oligoallergenic dietary treatment and the intestinal absorption of a protein antigen, cow milk beta-lactoglobulin (BLG) in 24 patients with chronic urticaria/angioedema syndrome 13 of... | cardiovascular diseases |
Intracarotid hydroxyethyl methacrylate solution causing stroke in dogs. Hydroxyethyl methacrylate (HEMA) has been advocated as a polymerizing solution with which to prevent deflation of detachable balloons in interventional neuroradiology. It is pertinent to know if unpolymerized HEMA would have untoward effects if acc... | nervous system diseases |
Topographic mapping of electrophysiologic measures in patients with homonymous hemianopia We analyzed electroencephalographic (EEG) activity and spatial distribution of the pattern-reversal visual evoked potential (PVEP) in 20 patients with unilateral lesions in the retrochiasmal visual pathways. Focal abnormalities th... | general pathological conditions |
Critical care transportation medicine: new concepts in pretransport stabilization of the critically ill patient. Regionalization of health care for trauma has become commonplace, and the same concept for critically ill medical/surgical patients is developing. Recent evidence suggests that current stabilization measures... | cardiovascular diseases |
Disability in persons hospitalized with AIDS. This study documents the types and degree of disability seen in persons with AIDS at discharge from acute hospitalization. Based on 37 discharge evaluations using the Functional Independence Measure (FIM), 60% required human assistance in at least one of 18 FIM areas. Thirt... | general pathological conditions |
Acute urinary retention secondary to Herpes simplex meningitis. We report a case of acute urinary retention in a 24-year-old man with Herpes simplex meningitis without genital lesions. Since the differential diagnosis in young patients who present with acute urinary retention also includes multiple sclerosis, lumbosacr... | nervous system diseases |
The effects of cyproheptadine on locomotion and on spasticity in patients with spinal cord injuries. The effects of cyproheptadine, a serotonergic antagonist, were studied in seven patients with spastic paresis of spinal origin. Six patients were included in a double blind crossover trial (maximal dose 24 mg/day). The ... | nervous system diseases |
Comparison of exercise performance in left main and three-vessel coronary artery disease. From a consecutive series of patients who underwent rest and exercise radionuclide angiography over several years, we retrospectively identified 34 patients with left main coronary artery disease and 103 patients with three-vessel... | cardiovascular diseases |
Turner's syndrome, fibromuscular dysplasia, and stroke. We report a 43-year-old woman who presented with a right frontoparietotemporal ischemic stroke. She had been diagnosed with Turner's syndrome during childhood and had a history of chronic estrogen therapy. Cerebral angiography showed lesions characteristics of fib... | cardiovascular diseases |
Mutational activation of the c-Ha-ras gene in liver tumors of different rodent strains: correlation with susceptibility to hepatocarcinogenesis. The frequency and pattern of mutations at codon 61 of the c-Ha-ras gene have been analyzed in 195 liver tumors and 132 precancerous liver lesions from various rodent strains w... | general pathological conditions |
Standards for analysis of ventricular late potentials using high-resolution or signal-averaged electrocardiography. A statement by a Task Force Committee of the European Society of Cardiology, the American Heart Association, and the American College of Cardiology. Sufficient data are available to recommend the use of t... | nervous system diseases |
Retinopathy of prematurity in infants with cyanotic congenital heart disease. We undertook a study of premature infants with cyanotic congenital heart disease to determine whether these infants develop retinopathy of prematurity despite a persistent hypoxemic state. Using the computerized registry of the neonatal inten... | general pathological conditions |
Polytetrafluoroethylene graft for spontaneous coronary dissection: 7-year follow-up. Spontaneous coronary artery dissection remains an exceedingly rare cause of myocardial ischemia. The patients are usually young and female, and the dissection is frequently fatal. The use of polytetrafluoroethylene as an aortocoronary ... | cardiovascular diseases |
Post-traumatic bile fistulae. Bile leakage after liver injury has been reported to be a complication associated with significant mortality. In a prospective study of 306 patients with liver injuries 13 (4%) developed a bile leak. There appear to be two groups of patients, those with a major bile duct injury (three pati... | general pathological conditions |
Anencephaly: clinical determination of brain death and neuropathologic studies. Twelve liveborn anencephalic infants were serially examined to determine if they would meet our clinical criteria for whole brain death within a 7-day period: Protocol 1 infants (6) received intensive care including intubation from birth; a... | nervous system diseases |
Spontaneous infarction of placental chorioangioma and associated regression of hydrops fetalis. We report a case of a large chorioangioma diagnosed prenatally with concomitant meconium peritonitis and hydrops fetalis in the second trimester. Spontaneous regression of the tumor occurred, associated with some resolution ... | neoplasms |
Ultrasound-guided hepatic cryosurgery in the treatment of metastatic colon carcinoma. Preliminary results. Cryosurgery, the in situ freezing of cancer, has been proposed in the past as a possible treatment for unresectable hepatic tumors. Its advantage lies in the fact that it is a very focal treatment sacrificing less... | neoplasms |
An open trial of high-dosage antioxidants in early Parkinson's disease. High dosages of tocopherol and ascorbate were administered to patients with early Parkinson's disease as a preliminary open-labeled trial for the eventual controlled double-blind study evaluating antioxidants as a test of the endogenous toxin hypot... | nervous system diseases |
Renal effects of angiotensin-converting enzyme inhibition in congestive heart failure. Some studies report that inhibition of angiotensin-converting enzyme (ACE) improves renal function in patients with congestive heart failure, whereas others report that renal deterioration is a frequent complication of treatment with... | cardiovascular diseases |
Skull base malignancy following long-term sinus mucocele and osteomyelitis. A case of skull base malignancy following long-term sinus mucocele is presented. While the similarity in clinical signs between sinus mucocele and malignancy has recently been emphasized in the literature, no previous case of skull base maligna... | neoplasms |
Surgical technique for implantation of the neurocybernetic prosthesis. The surgical technique for the implantation of the neurocybernetic prosthesis is described in detail. This procedure is straightforward and is easily carried out by surgeons familiar with carotid surgery. | nervous system diseases |
Fluctuations of interictal brain imaging in repeated 123I-IMP SPECT scans in an epileptic patient. Single photon emission computed tomography (SPECT) brain scans with N-isopropyl-(iodine 123) p-iodoamphetamine (123I-IMP) were performed three times in interictal periods in a 35-year-old man with intractable frontal lobe... | nervous system diseases |
Effects of milk, prostaglandin, and antacid on experimentally induced duodenitis in the rat. Use of myeloperoxidase as an index of inflammation. Ulcerogenesis of the duodenal mucosa frequently involves an inflammatory reaction with infiltration of leukocytes. Measurement of neutrophil myeloperoxidase activity might thu... | digestive system diseases |
Prospective observations of 100 high-risk neonates by high-field (1.5 Tesla) magnetic resonance imaging of the central nervous system. II. Lesions associated with hypoxic-ischemic encephalopathy. One hundred neonates determined prospectively to be at risk for neurologic handicap underwent magnetic resonance imaging wit... | general pathological conditions |
Stunned myocardium and myocardial collagen damage: differential effects of single and repeated occlusions. It has been suggested that collagen loss and damage is responsible for the dysfunction seen in stunned myocardium. To test this hypothesis we compared collagen in canine hearts stunned by repeated occlusion with c... | general pathological conditions |
Catecholaminergic systems in the medulla oblongata in parkinsonian syndromes: a quantitative immunohistochemical study in Parkinson's disease, progressive supranuclear palsy, and striatonigral degeneration. We investigated tyrosine-hydroxylase (TH)-immunoreactive neurons in the medulla oblongata corresponding to the A1... | nervous system diseases |
The clinical importance of drug interactions with antiulcer therapy. The overall safety of a given drug is determined by its toxicity, side effects, and drug-drug interactions. Thus, a clarification of the mechanisms, importance, and clinical implications of any drug-drug interaction with antiulcer therapy is critical ... | digestive system diseases |
Anterior lingual mandibular salivary gland defect. Evaluation of twenty-four cases. Lingual mandibular salivary gland defects in the posterior part of the mandible are not uncommon. Analogous defects in the anterior region, however, are rare, and the four new cases presented in this report bring the total number of rep... | general pathological conditions |
Low rate of treatment of hypercholesterolemia by cardiologists in patients with suspected and proven coronary artery disease. BACKGROUND. Although specific guidelines for the treatment of hypercholesterolemia have been published, it is not known whether physicians treating patients likely to have lipid disorders have a... | cardiovascular diseases |
Left ventricular asynchrony: an indicator of regional myocardial dysfunction. There is a marked heterogeneity of myocardial wall thickening within the left ventricle and among different individuals. It is therefore difficult to detect regional myocardial dysfunction from absolute values of systolic wall thickening. We ... | cardiovascular diseases |
Lung thallium-201 uptake during exercise emission computed tomography. To test whether the analysis of lung uptake is worth adding to the interpretation of exercise thallium-201 (201TI) emission computed tomography (ECT), a lung/heart ratio of 201TI uptake was measured from an anterior image during ECT in 25 clinically... | cardiovascular diseases |
Modulation of neurogenic inflammation by neutral endopeptidase. The enzyme neutral endopeptidase (NEP) is bound to the membranes of selected cells in the airways that have receptors for tachykinins. The location of the enzyme, along with its selectivity of substrates (tachykinins are a preferred substrate), allows the ... | general pathological conditions |
Managing geriatric arrhythmias, II: Drug selection and use [published erratum appears in Geriatrics 1991 Jun;46(6):100] Age-related impairments in antiarrhythmic drug distribution, metabolism, and excretion may result in accumulation of these potent drugs, increasing the risk of adverse drug reactions and drug interact... | general pathological conditions |
Risk factors for transmission of hepatitis B virus to Gambian children [published erratum appears in Lancet 1990 Dec 22-29;336(8730):1596] Risk factors for hepatitis B virus transmission were examined in 973 Gambian children aged 6 months to 5 years. 33% had evidence of infection with hepatitis B virus and a third of t... | general pathological conditions |
The IVH complex of lesions: cerebrovascular injury in the preterm infant. The term intraventricular hemorrhage has become associated with a variety of cerebrovascular insults in preterm infants. Because of a shared pathophysiology and timing, these are the neurologic lesions to search for when evaluating sick preterm i... | general pathological conditions |
Detection and assessment of unstable angina using myocardial perfusion imaging: comparison between technetium-99m sestamibi SPECT and 12-lead electrocardiogram. Forty-five studies using technetium-99m (Tc-99m) sestamibi single photon emission computed tomography (SPECT) were performed on patients hospitalized for spont... | cardiovascular diseases |
Anatomic, metabolic, neuropsychological, and molecular genetic studies of three pairs of identical twins discordant for dementia of the Alzheimer's type. Three pairs of twins, each with proved monozygosity, were shown to be discordant for dementia of the Alzheimer's type and to have remained discordant for periods of 8... | general pathological conditions |
A giant renal artery aneurysm diagnosed post partum. We report a case of a 5.8 cm. right renal artery aneurysm diagnosed intact 8 weeks post partum. Rupture of a renal arterial aneurysm during pregnancy is a rare but well described catastrophic event. There are no previous reports of an intact renal artery aneurysm dia... | cardiovascular diseases |
Rat soleus muscle ultrastructure after hindlimb suspension. The aim of the present investigation was to determine, by quantitative electron microscopy, the effects of a 5-wk tail-suspension period on rat soleus muscle ultrastructure. A marked decline (-60%) in muscle mass occurred. The mean fiber cross-sectional area d... | nervous system diseases |
Murine mast cells synthesize basement membrane components. A potential role in early fibrosis. Mast cells are resident in tissues, particularly in association with endothelial and epithelial cell basement membranes, and increase at sites of inflammation, injury, and fibrosis. Although mast cells are known to both relea... | general pathological conditions |
Gunshot wounds to the cervical spine. A retrospective review was performed on 28 patients with low-velocity gunshot wounds to the cervical spine. These composed 31% of all spinal gunshot wounds seen during the study period between 1979 and 1988. Surgical decompression did not seem to improve neurologic recovery in eith... | general pathological conditions |
Balloon valvuloplasty for fungal endocarditis induced stenosis of a bioprosthetic tricuspid valve. Palliative treatment was provided without complications by double balloon valvuloplasty of a stenotic porcine tricuspid valve in a patient with fungal endocarditis. With two 15 mm diameter valvulotomy balloons the peak tr... | cardiovascular diseases |
Obstructive sleep apnoea in children undergoing routine tonsillectomy and adenoidectomy. Sleep screening was used to discover the incidence of sleep apnoea in 50 children undergoing routine adenotonsillectomy for recurrent upper respiratory tract infections, randomly selected from the waiting list. Preoperative assessm... | general pathological conditions |
The "all-autogenous" tissue policy for infrainguinal reconstruction questioned. In 33% of patients referred for infrainguinal reconstruction for limb-threatening ischemia (mean preoperative ankle-arm index [AAI] = 0.26), no suitable autogenous reconstruction was possible. In 40% of cases, intraoperative pre-bypass cont... | cardiovascular diseases |
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