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60f08379_P_Purdue_Flashcards___Cram_com__1
[2] the hilus of the organ facing dorsocranially. (it is the broad "top" of the heart) it receives the great veins and sends out the great arteries. [1]
Base
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[2] Seen from the right side of the heart, with the venae cavae entering it [1]
Right atrium
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[2] The chamber into which the pulmonary veins empty [1]
Left Atrium
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[2] Makes up most of the heart on the right side, below the coronary groove. It "wraps" around the cranial side of the heart to continue as the pulmonary trunk [1]
Right Ventricle
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[2] the wall separating the ventricles [1]
Septum (interventricular septum)
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[2] the ear-shaped appendage of either atrium of the heart. formerly, the atrium of the heart. [1]
Auricles
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[2] Coronary arteries [1]
The arteries encircling the base of the heart like a crown. These are the first branches off the aorta.
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[2] Pulmonary Valve (semilunar) [1]
The valve between the conus of the right ventricle and the pulmonary trunk. It is similar to the aortic valve, but of lighter construction.
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[2] Aortic Valve (semilunar) [1]
The three semilunar cusps attached to the aortic fibrous ring in the origin of the aorta.
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[2] Pericardium [1]
The fibroserous sac enclosing the heart; composed fo the fibrous and serous pericardium covered by mediastinal (pericardiac) pleura
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[2] Parietal serous pericardium [1]
lines the inner surface of the fibrous pericardium (considered a wall). It reflects onto the surface of the heart as the visceral layer.
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[2] Pericardial Mediastinal pleura [1]
the serosa on the mediastinum; part of the mediastinal pleura on either side of the pericardium
[]
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[2] serous pericardium [1]
a serous membrane forming a closed cavity. It covers the heart (visceral layer) and lines the inner surface of the fibrous pericardial sac (parietal layer)
[]
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[2] parietal layer [1]
lines the inner surface of the fibrous pericardium. it reflects onto the surface of the hears as the visceral layer.
[]
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[2] visceral layer (epicardium) [1]
a thin layer of mesothelium covering the surface of the heart. The epicardium is the visceral layer of the serous pericardium. covers the myocardium of the heart closely.
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[2] pericardial cavity [1]
a potential space between the visceral and parietal layers of serous pericardium. It has approx. 1ml of yellow fluid btwn the layers which acts as a lubricant to allow the heart freedom of movement during contraction. Other serous body cavities have almost no fluid.
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[2] endocardium [1]
a thin mesotheial layer lining the atria and ventricles. This layer is continuous with the endothelium lining the great vessels entering and leaving the heart
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[2] right atrioventricular valve [1]
also known as the tricuspid valve, operates the right AV opening. There are only 2 major cusps (parietal and septal) in the dog, with intervening secondary cusps. In man and other domestic species there are 3 major cusps (angular, parietal and septal) thus "tri-".
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[2] left atrioventricular valve [1]
similar to the right AV valve, but has a heavier construction due to greater pressure of the left ventricle during contraction (systole). (A miter is a two cusp hat worn by bishops in the Catholic church. Someone thought they looked like the left AV valve, hence mitral)
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[2] chordae tendineae [1]
(tendinous cords) the though strands anchoring the free edges of the atrioventricular (AV) valves to the papillary muscles and preventing eversion of the valve leaflets into the atrium upon ventricular contraction (systole)
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[2] papillary muscles [1]
the muscular projections serving as attachments for the tendinous cords (chordae tendineae) of the atrioventricular (AV) valves.
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[2] facial artery [1]
Linguofacial artery; branches of the external carotid artery. The facial artery winds around the ventral border of the mandible to supply the face. Also known as separate lingual and facial arteries
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[2] facial vein [1]
Maxillary and linguofacial veins join to form the external jugular vein. The external jugular veins and subclavian veins join to form the brachiocephalic vein in carnivores and pigs. The brachiocephalic veins then join to form the cranial vena cava. In horses & ruminants the external jugular veins and subclavian veins ...
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[2] maxillary artery [1]
The direct continuation of the external carotid artery to the space below the orbit (the pterygopalatine fossa). Its branches supply the orbit, teeth, chin nose, nasal cavity and palate.
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[2] maxillary vein [1]
Maxillary and linguofacial veins join to form the external jugular vein. The external jugular veins and subclavian veins join to form the brachiocephalic vein in carnivores and pigs. The brachiocephalic veins then join to form the cranial vena cava. In horses & ruminants the external jugular veins and subclavian veins ...
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[2] aorta [1]
The great artery leaving the left ventricle and arching caudally. It sends oxygenated blood from the left heart to the heart itself and to the rest of the body through its systemic branches.
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[2] aortic arch [1]
The continuation of the ascending aorta, it sends branches to the head, neck and thoracic limbs
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[2] descending aorta [1]
the part of the aorta caudal to the aortic arch, divided into the thoracic aorta and the abdominal aorta by the diaphragm.
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[2] ascending aorta [1]
the initial part of the aorta, originating from the left ventricle at the center of the heart's base
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[2] common cartoid artery - right and left [1]
Ascend the neck to supply the head, face and brain. Dogs-arise separately; ungulates (hooved animals) - arise by a short, common bicarotid trunk
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[2] subclavian artery - right and left [1]
supply the neck, thoracic limb and the cranial portion of the thoracic wall. Each has many branches: Vertebral artery, Costocervical trunk, Cuperficial cervical artery, internal thoracic artery.
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[2] coronary artery - right and left [1]
The arteries encircling the base of the heart like a crown. These are the first branches off the aorta. The right coronary artery originates from the right aortic sinus. It courses cranially under the right auricle and then to the right in the coronary groove. In some species it continues as the subsinuousal interventr...
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[2] brachial artery [1]
continuation of the axillary artery on the medial aspect of the arm. It continues as the median artery in the forearm after giving off the common interosseous artery
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[2] ulnar artery [1]
Usually arises from the median artery
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[2] median artery [1]
The continuation of the brachial artery past the common interosseous arterhy. It courses distally with the median nerve on the medial side of the forearm under the flexor carpi radialis muscle. The median artery is the largest artery in the manus in all the domestic species, except the cat (its main supply is the radia...
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[2] radial artery [1]
runs cranial to the median artery on the radius
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[2] Carotid Artery (contained in carotid sheath) [1]
a portion of the cervical fascia enclosing the carotid artery, the internal jugular vein, and the vagus nerve.
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[2] Pulmonary artery [1]
two branches of the pulmonary trunk carrying blood to the lungs; one to the right lung, one to the left lung
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[2] axillary arteries [1]
The direct continuation of the subclavian artery past the first rib to supply the thoracic limb. It supplies the structures of the shoulder and continues as the brachial artery in the arm.
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[2] brachiocephalic artery (brachiocephalic truck) [1]
First branch of the arch of the aorta. As its name implies, it extends cranially to supply the right limb, neck and head. The brachiocephalic trunk gives off the left common carotid artery and then terminates in the right common carotid and right subclavian artery.
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[2] cervical vertebral arteries [1]
a branch of the subclavian artery it arises medially to the costocervical trunk. Traveling with the vertebral nerve toward the neck, they enter the transverse canal of the cervical vertebrae. The vertebral artery usually arises before the costocervical trunk.
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[2] celiac artery [1]
The first visceral branch of the abdominal aorta, arising unpaired between the crura of the diaphragm. It terminates as the hepatic, splenic and left gastric arteries supplying the cranial part of the GI tract.
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[2] cranial mesenteric artery [1]
The largest visceral branch of the abdominal aorta, arising just caudal to the origin of the celiac artery. It courses caudoventrally in the mesentery to supply most of the intestines.
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[2] renal arteries [1]
originating from the aorta caudal to the cranial mesenteric artery and pass each kidney
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[2] ovarian artery [1]
The convoluted artery supplying the ovary and arising from the abdominal aorta.
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1
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6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] testicular artery [1]
The convoluted artery supplying the testicle and arising from the abdominal aorta.
[]
Veterinary Anatomy Circulatory System-VTDLP Purdue Flashcards - Cram.com
1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Caudal Mesenteric Artery [1]
third and last unpaired branch arises from the caudal aorta and passes in the mesocolon to supply the descending colon and rectum. Smallest unpaired major branch of the abdominal aorta
[]
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1
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6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Median Sacral Artery [1]
The unpaired terminal branch of the aorta that passes on mid line below the sacrum.
[]
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1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Uterine Artery [1]
The main blood supply to the uterus. It arises differently in the different species.
[]
Veterinary Anatomy Circulatory System-VTDLP Purdue Flashcards - Cram.com
1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Femoral Artery [1]
the continuation of the external iliac artery through the femoral triangle, passing distally to continue as the popliteal artery caudal to the stifle joint
[]
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1
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6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Saphenous Artery [1]
arises from the femoral artery in the femoral triangle. It passes subcutaneously with the medial saphenous vein and saphenous nerve on the medial thigh. Past the stifle it divides into cranial and caudal branches in the carnivores and horse
[]
Veterinary Anatomy Circulatory System-VTDLP Purdue Flashcards - Cram.com
1
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6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Popliteal Artery [1]
the continuation of the femoral artery after the caudal femoral artery. Passing btwn the 2 heads of the gastrocnemisus muscle, it branches into cranial and caudal tibial aa.
[]
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1
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6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Caranial Tibial Artery [1]
passes through the interosseous space and then distally on the cranial surface of the crus with the deep branch of the fibular nerve
[]
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1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Dorsal Pedal Artery [1]
The direct continuation of the cranial tibial artery over the flexor surface of the tarsus
[]
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1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Intercostal Arteries [1]
are formed by the anastomoses of ventral intercostal artery of the internal thoracic and musculophrenic aa. and the dorsal intercostal a. of the costocervical trunk and aorta. They pass on the caudal border of the ribs in the intercostal spaces with like named veins and nerves.
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1
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6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Lumbar Arteries [1]
any artery of the usu. 4 pairs that arise from the back of the aorta opposite the lumbar vertebrae and supply the muscles of the loins
[]
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1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] External iliac arteries [1]
the large terminal branches of the caudal aorta near the caudal mesenteric artery that pass to the pelvic limbs.
[]
Veterinary Anatomy Circulatory System-VTDLP Purdue Flashcards - Cram.com
1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] internal iliac arteries [1]
the termination of the aorta passing to supply the viscera of the pelvis and part of the hip and thigh
[]
Veterinary Anatomy Circulatory System-VTDLP Purdue Flashcards - Cram.com
1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] External Jugular Vein [1]
The large vein in the neck returning blood from the head to the heart. Empties into the brachiocephalic vein in carnivores and pigs; directly into the cranial vena cava in ruminants and horses
[]
Veterinary Anatomy Circulatory System-VTDLP Purdue Flashcards - Cram.com
1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Azygos Vein [1]
A single vein arising in the abdomen as a branch of the ascending lumbar vein. It passes upward through the aortic hiatus of the diaphragm into the thorax, then along the right side of the vertebral column to the level of the 4th thoracic vertebra, where it turns and enters the superior vena cava.
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1
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6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Thoracic Duct [1]
The major lymphatic vessel draining the entire body, except the right thoracic limb, right cranial thorax, and right side of the neck. It begins at the cisterna chyli, passes through the aortic hiatus cranally on the right side between the azygos vein and the aorta. Passing to the left side of the thorax in the cranial...
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Veterinary Anatomy Circulatory System-VTDLP Purdue Flashcards - Cram.com
1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Vena Cava-cranial & caudal [1]
Great vessle emptying into the cranial or caudal part of the right atrium. Cranial returns blood from the head, neck thoracic limbs and cranial part of the wall of the thoracic cavity. The caudal part returns blood to the heart fromt he abdomen, pelvis and pelvic limbs
[]
Veterinary Anatomy Circulatory System-VTDLP Purdue Flashcards - Cram.com
1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] cephalic vein [1]
arises fro the digital veins on the palmar aspect of the paw. It extends proximally around the medial side of the forearm just above the carpus to reach the cranial surface of the limb. Here it is joined by the accessory cephalic vein
[]
Veterinary Anatomy Circulatory System-VTDLP Purdue Flashcards - Cram.com
1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] accessory cephalic vein [1]
arises fromt he digital veins on the dorsal surface of the paw. It extends proximally to join the cephalic vein above the carpus in the carnivores and ox and near the elbow in the horse
[]
Veterinary Anatomy Circulatory System-VTDLP Purdue Flashcards - Cram.com
1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] portal vein [1]
the large vein carrying essentially all the blood from the abdominal viscera to the liver and its internal sinusoids. Hepatic veins located inside the liver, return to the caudal vena cava
[]
Veterinary Anatomy Circulatory System-VTDLP Purdue Flashcards - Cram.com
1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] internal iliac vein [1]
The internal iliac vein (hypogastric vein) begins near the upper part of the greater sciatic foramen, passes upward behind and slightly medial to the hypogastric artery and, at the brim of the pelvis, joins with the external iliac vein to form the common iliac vein.
[]
Veterinary Anatomy Circulatory System-VTDLP Purdue Flashcards - Cram.com
1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] external iliac vein [1]
The external iliac veins are large veins that connect the femoral veins to the common iliac veins. Their origin is at the inferior margin of the inguinal ligaments and they terminate when they join the internal iliac veins (to form the common iliac veins).
[]
Veterinary Anatomy Circulatory System-VTDLP Purdue Flashcards - Cram.com
1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
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[2] femoral vein [1]
a vein that accompanies the femoral artery in the same sheath; a continuation of the popliteal vein; becomes the external iliac vein
[]
Veterinary Anatomy Circulatory System-VTDLP Purdue Flashcards - Cram.com
1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Saphenous Vein-Medial and Lateral-pulse site [1]
The saphenous vein runs from the body down the inside of the rear leg and then crosses to the outside of the leg above the hock Above the hock the vein runs diagonally across the leg, where it is easier to see. It is best to shave this area in the same manner as the cephalic vein.
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Veterinary Anatomy Circulatory System-VTDLP Purdue Flashcards - Cram.com
1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Linguofacial artery- pulse site [1]
just caudal to lateral canthus of eye in horse
[]
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1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Maxillary artery-pulse site [1]
facial just under the neck
[]
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1
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6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
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[2] Median Sacral artery-pulse site [1]
in the forearm dorsal side
[]
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1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
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[2] Femoral artery-pulse site [1]
inside hind leg
[]
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1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Brachial artery-pulse site [1]
elbow area
[]
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1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Femoral vein-venipuncture site [1]
inside hind leg
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Veterinary Anatomy Circulatory System-VTDLP Purdue Flashcards - Cram.com
1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] cephalic vein-venipuncture site [1]
in dog most common site forearm area
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1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] lateral saphenous vein-venipuncture site [1]
outside hind leg - 3rd most common site in dogs- poor choice
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Veterinary Anatomy Circulatory System-VTDLP Purdue Flashcards - Cram.com
1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] jugular vein-venipuncture site [1]
2nd most common choice, neck
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1
http://www.cram.com/flashcards/veterinary-anatomy-circulatory-system-vtdlp-purdue-1499750
6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
60f08379_P_Purdue_Flashcards___Cram_com__1
[2] Ductus arteriosus [1]
one of the 3 shunts in the fetal circulation- arterial duct the shunt between the pulmonary trunk and the aorta, diverting most of the blood from the pulmonary trunk (pulmonic circulation) to the aorta (systemic circulation)
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6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
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[2] Patent ductus arteriosus (PDA) [1]
the arterial duct doesn't close after birth. This should be corrected early through a left intercostal incision throught the 4th intercostal space. The ductus is carefully isolated and ligated.
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6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
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[2] Ductus venosus [1]
one of the 3 shunts in the fetal circulation-the fetal shunt from the unbilical vein directly through the liver to the caudal vena cava, bypassing the liver sinusoids.
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6/1438042981576.7_20150728002301-00064-ip-10-236-191-2_392985882_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
To inform family to risk to other family members
Why would genetic counseling be necessary?
[]
Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
12%
Single-gene genetic treatment is completely effective in ___ of patients.
[]
Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
If the basic biochemical defect is known
What makes treatment of genetic disease more successful?
[]
Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
absence of long-term side effects
With regards to long-term treatment assessment, it is imporatant to remember that the absence of short-term side effects doesn't mean___
[]
Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
a high degree of diagnostic precision (must know locus and class of allele)
Optimal treatment of genetic diseases require ___
[]
Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
create the same disorder
Many problems may _____ but require different treatments.
[]
Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
Therapy directed at clinical phenotype (may be medical or surgical)
This level of treatment is often the only therapy available and may the only treatment needed.
[]
Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
dietary restriction replacement diversion inhibition depletion
What are the 5 steps to approach treatment of metabolic abnormalities?
[]
Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
highly effective but lifelong and difficult committment.
Dietary restriction is ____
[]
Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
1. amino acid catabolic pathways 2. severe restriction of dietary protein
Most treatable genetic diseases involve ____ and are treated with ___
[]
Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
give the patient the item missing due to genetic disease.
What does the replacement stage of treatment of metabolic abnormaltiy involve
[]
Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
diversion
this stage of treatment of metabolic abnormalities uses enhancement of alternative metabolic pathways to reduce concentration of a harmful metabolite.
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Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
using pharmacological inhibition of enzymes to modify inborn metabolic errors.
What is inhibition with regards to treatment of metabolic abnormalities?
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Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
inhibit hepatic cholesterol synthesis while diverting cholesterol
The best treatment for familial hypercholesterolemia?
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Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
Depletion (tx metabolic abnormalities).
The direct removal of accumulated harmful products from the body is ____
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Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
draw blood to eliminate iron in patients with hemochromatosis (or polycythemia)
What is an example of depletion when treating metabolic abnormalities?
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Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
1. treatment at the level of the protein 2. modulation of gene expression 3. modification of somatic genome by transplantation 4. gene therapy
What are the 4 basic true "genetic treatments" -
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Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
treatment at the level of the protein
Functional incease to fixing structural abnormalities of affected proteins is an example of ____
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Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json
fdef2979__disease_Flashcards___Cram_com___treatment_of_genetic_disease_
disorders where functional proteins are not being synthesized
What is the only instance that treatment at the level of the protein can't really work with?
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Genetics- treatment of genetic disease Flashcards - Cram.com
What is the objective of treatment of genetic disease?
http://www.cram.com/flashcards/genetics-treatment-of-genetic-disease-2192567
6/1438042988860.4_20150728002308-00307-ip-10-236-191-2_387818823_0.json