uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
values | bio_category stringclasses 14
values |
|---|---|---|---|---|---|---|---|---|
Q16.541 | Q16 | What Small molecule therapies have been approved by the FDA to treat Marfan syndrome? | There are no drug Small molecule therapies approved to treat Marfan syndrome. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "marfan syndrome" OR LOWER(mesh_heading) = "... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.766 | Q16 | What Small molecule therapies have been approved by the FDA to treat angiomyolipoma? | Everolimus is the only Small molecule therapy approved by the FDA to treat angiomyolipoma. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "angiomyolipoma" OR LOWER(mesh_heading) = "a... | [{'UUID': 'DrugTargetsIndication121923_text_1084964', 'drugName': 'Everolimus', 'tradeNames_list': "['Afinitor', 'Afinitor disperz', 'Certican', 'Votubia', 'Zortress']", 'drugType': 'Small molecule', 'actionType': 'inhibitor', 'target': 'ENSG00000088832', 'approvedSymbol': 'FKBP1A', 'approvedName': 'FKBP prolyl isomera... | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1071 | Q16 | What Small molecule therapies have been approved by the FDA to treat fibromatosis? | There are no drug Small molecule therapies approved to treat fibromatosis. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "fibromatosis" OR LOWER(mesh_heading) = "fib... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1208 | Q16 | What Small molecule therapies have been approved by the FDA to treat interstitial nephritis? | There are no drug Small molecule therapies approved to treat interstitial nephritis. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "interstitial nephritis" OR LOWER(mesh_headi... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.247 | Q16 | What Protein therapies have been approved by the FDA to treat osteogenesis imperfecta? | There are no drug Protein therapies approved to treat osteogenesis imperfecta. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "osteogenesis imperfecta" OR LOWER(mesh_head... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1136 | Q16 | What Small molecule therapies have been approved by the FDA to treat hemophagocytic syndrome? | There are no drug Small molecule therapies approved to treat hemophagocytic syndrome. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "hemophagocytic syndrome" OR LOWER(mesh_head... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.792 | Q16 | What Small molecule therapies have been approved by the FDA to treat astrocytoma? | Everolimus is the only Small molecule therapy approved by the FDA to treat astrocytoma. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "astrocytoma" OR LOWER(mesh_heading) = "astr... | [{'UUID': 'DrugTargetsIndication121923_text_1084953', 'drugName': 'Everolimus', 'tradeNames_list': "['Afinitor', 'Afinitor disperz', 'Certican', 'Votubia', 'Zortress']", 'drugType': 'Small molecule', 'actionType': 'inhibitor', 'target': 'ENSG00000088832', 'approvedSymbol': 'FKBP1A', 'approvedName': 'FKBP prolyl isomera... | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.493 | Q16 | What Small molecule therapies have been approved by the FDA to treat Hot flashes? | There are no drug Small molecule therapies approved to treat Hot flashes. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "hot flashes" OR LOWER(mesh_heading) = "hot ... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.155 | Q16 | What Protein therapies have been approved by the FDA to treat epidermolysis bullosa? | There are no drug Protein therapies approved to treat epidermolysis bullosa. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "epidermolysis bullosa" OR LOWER(mesh_headin... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.969 | Q16 | What Small molecule therapies have been approved by the FDA to treat cystic, mucinous, and serous neoplasm? | There are no drug Small molecule therapies approved to treat cystic, mucinous, and serous neoplasm. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "cystic, mucinous, and serous neoplasm" OR L... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.861 | Q16 | What Small molecule therapies have been approved by the FDA to treat carcinoid syndrome? | There are no drug Small molecule therapies approved to treat carcinoid syndrome. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "carcinoid syndrome" OR LOWER(mesh_heading) ... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1323 | Q16 | What Small molecule therapies have been approved by the FDA to treat migraine without aura? | There are no drug Small molecule therapies approved to treat migraine without aura. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "migraine without aura" OR LOWER(mesh_headin... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.629 | Q16 | What Small molecule therapies have been approved by the FDA to treat Smith-Magenis syndrome? | Tasimelteon is the only Small molecule therapy approved by the FDA to treat Smith-Magenis syndrome. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "smith-magenis syndrome" OR LOWER(mesh_headi... | [{'UUID': 'DrugTargetsIndication121923_text_1094674', 'drugName': 'Tasimelteon', 'tradeNames_list': "['Hetlioz', 'Hetlioz lq']", 'drugType': 'Small molecule', 'actionType': 'agonist', 'target': 'ENSG00000168412', 'approvedSymbol': 'MTNR1A', 'approvedName': 'melatonin receptor 1A', 'yearOfFirstApproval': 2014, 'max_phas... | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.690 | Q16 | What Small molecule therapies have been approved by the FDA to treat Zollinger-Ellison Syndrome? | There are 2 Small molecule therapy drugs that are approved to treat Zollinger-Ellison Syndrome which are as follows: Pantoprazole Sodium and Esomeprazole Magnesium. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "zollinger-ellison syndrome" OR LOWER(mesh_h... | [{'UUID': 'DrugTargetsIndication121923_text_1097748', 'drugName': 'Pantoprazole Sodium', 'tradeNames_list': "['Pantoprazole sodium', 'Protonix', 'Protonix iv']", 'drugType': 'Small molecule', 'actionType': 'inhibitor', 'target': 'ENSG00000105675', 'approvedSymbol': 'ATP4A', 'approvedName': 'ATPase H+/K+ transporting su... | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1570 | Q16 | What Small molecule therapies have been approved by the FDA to treat renal carcinoma? | Axitinib is the only Small molecule therapy approved by the FDA to treat renal carcinoma. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "renal carcinoma" OR LOWER(mesh_heading) = "... | [{'UUID': 'DrugTargetsIndication121923_text_689158', 'drugName': 'Axitinib', 'tradeNames_list': "['Inlyta']", 'drugType': 'Small molecule', 'actionType': 'inhibitor', 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert domain receptor', 'yearOfFirstApproval': 2012, 'max_phase_for_ind': ... | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.573 | Q16 | What Small molecule therapies have been approved by the FDA to treat Olfactory Neuroblastoma? | There are no drug Small molecule therapies approved to treat Olfactory Neuroblastoma. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "olfactory neuroblastoma" OR LOWER(mesh_head... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1676 | Q16 | What Small molecule therapies have been approved by the FDA to treat syphilis? | There are no drug Small molecule therapies approved to treat syphilis. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "syphilis" OR LOWER(mesh_heading) = "syphili... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.18 | Q16 | What Protein therapies have been approved by the FDA to treat Abnormality of blood and blood-forming tissues? | There are no drug Protein therapies approved to treat Abnormality of blood and blood-forming tissues. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "abnormality of blood and blood-forming tiss... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.128 | Q16 | What Protein therapies have been approved by the FDA to treat chronic myelogenous leukemia? | There are no drug Protein therapies approved to treat chronic myelogenous leukemia. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "chronic myelogenous leukemia" OR LOWER(mesh... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1359 | Q16 | What Small molecule therapies have been approved by the FDA to treat narcolepsy? | There are 2 Small molecule therapy drugs that are approved to treat narcolepsy which are as follows: Armodafinil and Sodium Oxybate. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "narcolepsy" OR LOWER(mesh_heading) = "narco... | [{'UUID': 'DrugTargetsIndication121923_text_418362', 'drugName': 'Dextroamphetamine', 'tradeNames_list': "['Dexedrine', 'Dextrostat', 'Xelstrym']", 'drugType': 'Small molecule', 'actionType': 'releasing agent', 'target': 'ENSG00000103546', 'approvedSymbol': 'SLC6A2', 'approvedName': 'solute carrier family 6 member 2', ... | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1289 | Q16 | What Small molecule therapies have been approved by the FDA to treat malignant pleural mesothelioma? | Pemetrexed is the only Small molecule therapy approved by the FDA to treat malignant pleural mesothelioma. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "malignant pleural mesothelioma" OR LOWER(me... | [{'UUID': 'DrugTargetsIndication121923_text_918480', 'drugName': 'Pemetrexed', 'tradeNames_list': "['Alimta', 'Pemfexy']", 'drugType': 'Small molecule', 'actionType': 'inhibitor', 'target': 'ENSG00000176890', 'approvedSymbol': 'TYMS', 'approvedName': 'thymidylate synthetase', 'yearOfFirstApproval': 2004, 'max_phase_for... | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1732 | Q16 | What Small molecule therapies have been approved by the FDA to treat urogenital neoplasm? | There are no drug Small molecule therapies approved to treat urogenital neoplasm. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "urogenital neoplasm" OR LOWER(mesh_heading)... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.935 | Q16 | What Small molecule therapies have been approved by the FDA to treat cocaine dependence? | There are no drug Small molecule therapies approved to treat cocaine dependence. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "cocaine dependence" OR LOWER(mesh_heading) ... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.988 | Q16 | What Small molecule therapies have been approved by the FDA to treat diabetic nephropathy? | There are no drug Small molecule therapies approved to treat diabetic nephropathy. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "diabetic nephropathy" OR LOWER(mesh_heading... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1728 | Q16 | What Small molecule therapies have been approved by the FDA to treat urgency urinary incontinence? | There are 4 Small molecule therapy drugs that are approved to treat urgency urinary incontinence which are as follows: Solifenacin Succinate, Fesoterodine Fumarate, Mirabegron, and Vibegron. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "urgency urinary incontinence" OR LOWER(mesh... | [{'UUID': 'DrugTargetsIndication121923_text_857279', 'drugName': 'Solifenacin Succinate', 'tradeNames_list': "['Solifenacin succinate', 'Vesicare', 'Vesicare ls']", 'drugType': 'Small molecule', 'actionType': 'antagonist', 'target': 'ENSG00000133019', 'approvedSymbol': 'CHRM3', 'approvedName': 'cholinergic receptor mus... | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.191 | Q16 | What Protein therapies have been approved by the FDA to treat ischemia reperfusion injury? | There are no drug Protein therapies approved to treat ischemia reperfusion injury. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "ischemia reperfusion injury" OR LOWER(mesh_... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1148 | Q16 | What Small molecule therapies have been approved by the FDA to treat heroin dependence? | There are no drug Small molecule therapies approved to treat heroin dependence. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "heroin dependence" OR LOWER(mesh_heading) =... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1000 | Q16 | What Small molecule therapies have been approved by the FDA to treat dilated cardiomyopathy? | There are no drug Small molecule therapies approved to treat dilated cardiomyopathy. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "dilated cardiomyopathy" OR LOWER(mesh_headi... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1719 | Q16 | What Small molecule therapies have been approved by the FDA to treat ulcerative colitis? | There are 6 Small molecule therapy drugs that are approved to treat ulcerative colitis which are as follows: Prednisone, Budesonide, Dexamethasone, Hydrocortisone, Balsalazide Disodium, and Mesalamine. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "ulcerative colitis" OR LOWER(mesh_heading) ... | [{'UUID': 'DrugTargetsIndication121923_text_217635', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1462 | Q16 | What Small molecule therapies have been approved by the FDA to treat peripheral arterial disease? | Vorapaxar Sulfate is the only Small molecule therapy approved by the FDA to treat peripheral arterial disease. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "peripheral arterial disease" OR LOWER(mesh_... | [{'UUID': 'DrugTargetsIndication121923_text_1193356', 'drugName': 'Vorapaxar Sulfate', 'tradeNames_list': "['Zontivity']", 'drugType': 'Small molecule', 'actionType': 'antagonist', 'target': 'ENSG00000181104', 'approvedSymbol': 'F2R', 'approvedName': 'coagulation factor II thrombin receptor', 'yearOfFirstApproval': 201... | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.610 | Q16 | What Small molecule therapies have been approved by the FDA to treat Recurrent tonsillitis? | There are no drug Small molecule therapies approved to treat Recurrent tonsillitis. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "recurrent tonsillitis" OR LOWER(mesh_headin... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.181 | Q16 | What Protein therapies have been approved by the FDA to treat infection? | There are no drug Protein therapies approved to treat infection. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "infection" OR LOWER(mesh_heading) = "infect... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.303 | Q16 | What Protein therapies have been approved by the FDA to treat systemic inflammatory response syndrome? | There are no drug Protein therapies approved to treat systemic inflammatory response syndrome. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "systemic inflammatory response syndrome" OR... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.500 | Q16 | What Small molecule therapies have been approved by the FDA to treat Hyperhidrosis? | There are no drug Small molecule therapies approved to treat Hyperhidrosis. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "hyperhidrosis" OR LOWER(mesh_heading) = "hy... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1595 | Q16 | What Small molecule therapies have been approved by the FDA to treat salivary gland cancer? | There are no drug Small molecule therapies approved to treat salivary gland cancer. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "salivary gland cancer" OR LOWER(mesh_headin... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1566 | Q16 | What Small molecule therapies have been approved by the FDA to treat refractive error? | There are no drug Small molecule therapies approved to treat refractive error. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "refractive error" OR LOWER(mesh_heading) = ... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1467 | Q16 | What Small molecule therapies have been approved by the FDA to treat peripheral vertigo? | There are no drug Small molecule therapies approved to treat peripheral vertigo. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "peripheral vertigo" OR LOWER(mesh_heading) ... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1552 | Q16 | What Small molecule therapies have been approved by the FDA to treat pulmonary sarcoidosis? | There are no drug Small molecule therapies approved to treat pulmonary sarcoidosis. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "pulmonary sarcoidosis" OR LOWER(mesh_headin... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.521 | Q16 | What Small molecule therapies have been approved by the FDA to treat Juvenile Myelomonocytic Leukemia? | There are no drug Small molecule therapies approved to treat Juvenile Myelomonocytic Leukemia. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "juvenile myelomonocytic leukemia" OR LOWER(... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1078 | Q16 | What Small molecule therapies have been approved by the FDA to treat focal segmental glomerulosclerosis? | There are no drug Small molecule therapies approved to treat focal segmental glomerulosclerosis. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "focal segmental glomerulosclerosis" OR LOWE... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.480 | Q16 | What Small molecule therapies have been approved by the FDA to treat Hepatic steatosis? | There are no drug Small molecule therapies approved to treat Hepatic steatosis. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "hepatic steatosis" OR LOWER(mesh_heading) =... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.158 | Q16 | What Protein therapies have been approved by the FDA to treat fallopian tube cancer? | There are no drug Protein therapies approved to treat fallopian tube cancer. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "fallopian tube cancer" OR LOWER(mesh_headin... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1253 | Q16 | What Small molecule therapies have been approved by the FDA to treat lichen planus? | There are no drug Small molecule therapies approved to treat lichen planus. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "lichen planus" OR LOWER(mesh_heading) = "li... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1204 | Q16 | What Small molecule therapies have been approved by the FDA to treat intermittent vascular claudication? | There are no drug Small molecule therapies approved to treat intermittent vascular claudication. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "intermittent vascular claudication" OR LOWE... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.17 | Q16 | What Protein therapies have been approved by the FDA to treat Abdominal Aortic Aneurysm? | There are no drug Protein therapies approved to treat Abdominal Aortic Aneurysm. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "abdominal aortic aneurysm" OR LOWER(mesh_he... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1081 | Q16 | What Small molecule therapies have been approved by the FDA to treat folliculitis? | There are no drug Small molecule therapies approved to treat folliculitis. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "folliculitis" OR LOWER(mesh_heading) = "fol... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1735 | Q16 | What Small molecule therapies have been approved by the FDA to treat uterine cancer? | There are no drug Small molecule therapies approved to treat uterine cancer. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "uterine cancer" OR LOWER(mesh_heading) = "u... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.550 | Q16 | What Small molecule therapies have been approved by the FDA to treat Mitral regurgitation? | There are no drug Small molecule therapies approved to treat Mitral regurgitation. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "mitral regurgitation" OR LOWER(mesh_heading... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.662 | Q16 | What Small molecule therapies have been approved by the FDA to treat Torticollis? | There are no drug Small molecule therapies approved to treat Torticollis. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "torticollis" OR LOWER(mesh_heading) = "tort... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1435 | Q16 | What Small molecule therapies have been approved by the FDA to treat pachyonychia congenita? | There are no drug Small molecule therapies approved to treat pachyonychia congenita. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "pachyonychia congenita" OR LOWER(mesh_headi... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1027 | Q16 | What Small molecule therapies have been approved by the FDA to treat enuresis? | There are no drug Small molecule therapies approved to treat enuresis. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "enuresis" OR LOWER(mesh_heading) = "enuresi... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1468 | Q16 | What Small molecule therapies have been approved by the FDA to treat peritoneal neoplasm? | Niraparib Tosylate is the only Small molecule therapy approved by the FDA to treat peritoneal neoplasm. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "peritoneal neoplasm" OR LOWER(mesh_heading)... | [{'UUID': 'DrugTargetsIndication121923_text_823336', 'drugName': 'Niraparib Tosylate', 'tradeNames_list': "['Zejula']", 'drugType': 'Small molecule', 'actionType': 'inhibitor', 'target': 'ENSG00000129484', 'approvedSymbol': 'PARP2', 'approvedName': 'poly(ADP-ribose) polymerase 2', 'yearOfFirstApproval': 2017, 'max_phas... | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.967 | Q16 | What Small molecule therapies have been approved by the FDA to treat cutaneous melanoma? | There are 5 Small molecule therapy drugs that are approved to treat cutaneous melanoma which are as follows: Vemurafenib, Encorafenib, Dabrafenib Mesylate, Binimetinib, and Trametinib Dimethyl Sulfoxide. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "cutaneous melanoma" OR LOWER(mesh_heading) ... | [{'UUID': 'DrugTargetsIndication121923_text_752095', 'drugName': 'Vemurafenib', 'tradeNames_list': "['Zelboraf']", 'drugType': 'Small molecule', 'actionType': 'inhibitor', 'target': 'ENSG00000157764', 'approvedSymbol': 'BRAF', 'approvedName': 'B-Raf proto-oncogene, serine/threonine kinase', 'yearOfFirstApproval': 2011,... | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.1656 | Q16 | What Small molecule therapies have been approved by the FDA to treat squamous cell intraepithelial neoplasia? | There are no drug Small molecule therapies approved to treat squamous cell intraepithelial neoplasia. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "squamous cell intraepithelial neoplasia" OR... | [] | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q16.285 | Q16 | What Protein therapies have been approved by the FDA to treat rheumatoid arthritis? | Cyclosporine is the only Protein therapy approved by the FDA to treat rheumatoid arthritis. | SELECT DISTINCT UUID, drugName, tradeNames_list, drugType, actionType, target, approvedSymbol, approvedName, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(efo_term) = "rheumatoid arthritis" OR LOWER(mesh_heading... | [{'UUID': 'DrugTargetsIndication121923_text_1100647', 'drugName': 'Cyclosporine', 'tradeNames_list': "['Capimune', 'Capsorin', 'Cequa', 'Cyclosporine', 'Deximune', 'GengrafIkervis', 'Neoral', 'Optimmune', 'Restasis', 'Restasis multidoseSandimmun', 'Sandimmune', 'Sangcya', 'Vanquoral', 'Verkazia']", 'drugType': 'Protein... | refined | Distinct, Multi-Filter, Similarity Search | Approval Status |
Q17.589 | Q17 | What gene does the drug Trandolapril target? | The drug Trandolapril targets the gene ACE. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3055', 'drugName': 'Trandolapril', 'tradeNames_string': 'Gopten, Mavik, Odrik, Trandolapril', 'drugSynonyms_string': 'Indolapril, NSC-758939, RU 44570, RU-44570, Trandolapril', 'linkedDiseasesDrug_string': 'Heart Failure (EFO_0003144), Hypertension (EFO_0000537), Cardiovascular Disease (EF... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1868 | Q17 | What gene does the drug Hydromorphone target? | The drug Hydromorphone targets the gene OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_245', 'drugName': 'Morphine', 'tradeNames_string': '', 'drugSynonyms_string': 'Anhydrous morphine, Avinza, Depodur, Hydromorphone hydrochloride impurity, morphine-, IDS-NM-009, Infumorph, Kadian, Morphia, Morphine, Morphine (anhydrous), Morphine anhydrous, Morphine extended release, Morphi... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1061 | Q17 | What gene does the drug Xl550 target? | The drug Xl550 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene NR3C2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4029', 'drugName': 'Xl550', 'tradeNames_string': '', 'drugSynonyms_string': 'CS-3150, Esaxerenone, XL-550, Xl550', 'linkedDiseasesDrug_string': 'Primary Aldosteronism (MONDO_0001422), Hypertension (EFO_0000537), Essential Hypertension (MONDO_0001134), Diabetic Nephropathy (EFO_0000401)', '... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1084 | Q17 | What gene does the drug Methohexital target? | The drug Methohexital targets 16 genes: GABRG2, GABRE, GABRA4, GABRQ, GABRD, GABRA3, GABRP, GABRA5, GABRG3, GABRB2, GABRB3, GABRG1, GABRA2, GABRB1, GABRA6 and GABRA1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_314', 'drugName': 'Methohexital', 'tradeNames_string': '', 'drugSynonyms_string': 'Methohexital, Methohexital civ, Methohexitone', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1960, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newLinkedTargets_string': 'GABRA1 (ENSG00000... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.925 | Q17 | What gene does the drug Phenylephrine Bitartrate target? | The drug Phenylephrine Bitartrate targets 3 genes: ADRA1D, ADRA1B and ADRA1A. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2414', 'drugName': 'Phenylephrine Bitartrate', 'tradeNames_string': '', 'drugSynonyms_string': 'Phenylephrine acid tartrate, Phenylephrine bitartrate, Phenylephrine hydrogen tartrate', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1973, 'maxClinicalTrialPhase': 4, 'drugIsApproved... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.73 | Q17 | What gene does the drug Cangrelor target? | The drug Cangrelor targets the gene P2RY12. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1075', 'drugName': 'Cangrelor Tetrasodium', 'tradeNames_string': 'Kengreal', 'drugSynonyms_string': 'AR-C69931MX, Cangrelor, Cangrelor tetrasodium, Cangrelor tetrasodium salt, Kengrexal', 'linkedDiseasesDrug_string': 'Recurrent Thrombophlebitis (HP_0004419), Myocardial Infarction (EFO_0000... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.435 | Q17 | What gene does the drug Bdtx189 target? | The drug Bdtx189 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 2 genes: ERBB2 and EGFR | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5069', 'drugName': 'Bdtx189', 'tradeNames_string': '', 'drugSynonyms_string': 'BDTX189, Bdtx-189, Bdtx189, Tuxobertinib', 'linkedDiseasesDrug_string': 'Neoplasm (EFO_0000616)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False, 'newLinkedTargets_string': 'EGFR (... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.911 | Q17 | What gene does the drug Midostaurin target? | The drug Midostaurin targets 16 genes: PRKCD, FLT3, PRKCE, KIT, PRKCI, PRKCH, PRKCZ, KDR, PRKCA, PRKCQ, PRKD3, PRKCG, PDGFRB, PRKD1, PRKCB and PDGFRA. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5667', 'drugName': 'Midostaurin', 'tradeNames_string': 'Rydapt', 'drugSynonyms_string': 'CGP 41251, CGP-41251, Midostaurin, NSC-656576, NVP-PKC412, PKC 412, PKC-412, Pkc-412', 'linkedDiseasesDrug_string': 'Rectum Cancer (EFO_1000657), Neoplasm (EFO_0000616), Leukemia (EFO_0000565), Liver D... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.922 | Q17 | What gene does the drug Mepazine target? | The drug Mepazine targets the gene MALT1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1830', 'drugName': 'Mepazine', 'tradeNames_string': '', 'drugSynonyms_string': 'III-2318, Lacumin, Mepasin, Mepazin, Mepazine base, Meprazine, Mesapin, Nothiazine, P-391, Pacatal, Pacatal base, Pacatol, Pakatal, Paxital, Pecatal, Pecazine', 'linkedDiseasesDrug_string': '', 'yearOfFirstAppr... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1679 | Q17 | What gene does the drug Pentazocine Lactate target? | The drug Pentazocine Lactate targets the gene SIGMAR1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_652', 'drugName': 'Pentazocine Lactate', 'tradeNames_string': 'Talwin', 'drugSynonyms_string': 'Pentazocine lactate, Talwin (lactate)', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newLinkedTargets_string': 'SIGMAR1 (ENS... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1272 | Q17 | What gene does the drug Fluspirilene target? | The drug Fluspirilene targets the gene DRD2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_899', 'drugName': 'Fluspirilene', 'tradeNames_string': 'Imap, Redeptin', 'drugSynonyms_string': 'Fluspirilene, Imap, MCN-JR-6218, R 6218, R-6218, Redeptin', 'linkedDiseasesDrug_string': 'Psychosis (EFO_0005407), Dementia (HP_0000726), Anxiety (EFO_0005230), Depressive Disorder (MONDO_00020... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1094 | Q17 | What gene does the drug Rafabegron target? | The drug Rafabegron is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene ADRB3. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2385', 'drugName': 'Rafabegron', 'tradeNames_string': '', 'drugSynonyms_string': 'AD-9677, Aj-9677, Rafabegron, TAK-677', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'newLinkedTargets_string': 'ADRB3 (ENSG00000188778)', 'n... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.389 | Q17 | What gene does the drug Meclofenamic Acid target? | The drug Meclofenamic Acid targets 3 genes: PTGS2, PTGS1 and ALOX5. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3725', 'drugName': 'Meclofenamate Sodium', 'tradeNames_string': 'Meclodium, Meclofenamate sodium, Meclomen', 'drugSynonyms_string': 'CL-583.NA SALT, Meclofenamate sodium, Meclofenamate sodium anhydrous, Meclofenamate sodium hydrate, Meclofenamic acid sodium, NSC-757088, Sodium meclofenamat... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.841 | Q17 | What gene does the drug Cedazuridine target? | The drug Cedazuridine targets the gene CDA. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2765', 'drugName': 'Cedazuridine', 'tradeNames_string': '', 'drugSynonyms_string': 'ASTX-727 COMPONENT CEDAZURIDINE, ASTX727 COMPONENT CEDAZURIDINE, Cedazuridine, E-7727, E7727', 'linkedDiseasesDrug_string': 'Neoplasm (EFO_0000616), Acute Myeloid Leukemia (EFO_0000222), Unspecified Periphe... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.774 | Q17 | What gene does the drug Hydroxyamphetamine Hydrobromide target? | The drug Hydroxyamphetamine Hydrobromide targets 9 genes: ADRA2A, ADRB1, ADRA2C, ADRA1A, ADRA1D, ADRA1B, ADRB3, ADRA2B and ADRB2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2950', 'drugName': 'Hydroxyamphetamine Hydrobromide', 'tradeNames_string': 'Paredrine', 'drugSynonyms_string': 'Hydroxyamfetamine hbr, Hydroxyamfetamine hydrobromide, Hydroxyamphetamine hbr, Hydroxyamphetamine hydrobromide, Hyroxyamfetamine hydrobromide, NSC-61065, Oxamphetamine hydrobromi... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1805 | Q17 | What gene does the drug Anileridine Hydrochloride target? | The drug Anileridine Hydrochloride targets 2 genes: OPRK1 and OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4594', 'drugName': 'Anileridine Hydrochloride', 'tradeNames_string': 'Leritine', 'drugSynonyms_string': 'Aldine, Anileridine dihydrochloride, Anileridine hcl, Anileridine hydrochloride, Anileridine hydrochloride cii, Apodol, Leritine dihydrochloride', 'linkedDiseasesDrug_string': '', 'year... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1992 | Q17 | What gene does the drug Delucemine target? | The drug Delucemine is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 7 genes: GRIN2B, GRIN2A, GRIN3A, GRIN2D, GRIN3B, GRIN1 and GRIN2C | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5026', 'drugName': 'Delucemine', 'tradeNames_string': '', 'drugSynonyms_string': 'Delucemine', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': -1, 'drugIsApproved': False, 'newLinkedTargets_string': 'GRIN1 (ENSG00000176884), GRIN2A (ENSG00000183454), GRI... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1066 | Q17 | What gene does the drug Paroxetine target? | The drug Paroxetine targets the gene SLC6A4. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4720', 'drugName': 'Paroxetine Hydrochloride', 'tradeNames_string': 'Paroxetine hydrochloride, Paxil, Paxil cr, Seroxat', 'drugSynonyms_string': 'NSC-758654, Paroxetine HCl, Paroxetine hydrochloride, Paroxetine hydrochloride anhydrous', 'linkedDiseasesDrug_string': 'Post-Traumatic Stress D... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.58 | Q17 | What gene does the drug Izokibep target? | The drug Izokibep is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene IL17A. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5580', 'drugName': 'Izokibep', 'tradeNames_string': '', 'drugSynonyms_string': 'ABY-035, Aby-035, Aby-035/afo2, Aby035, IMG-020, Izokibep', 'linkedDiseasesDrug_string': 'Uveitis (EFO_1001231), Psoriasis (EFO_0000676), Ankylosing Spondylitis (EFO_0003898), Psoriatic Arthritis (EFO_0003778),... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1688 | Q17 | What gene does the drug Olmesartan Medoxomil target? | The drug Olmesartan Medoxomil targets the gene AGTR1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2021', 'drugName': 'Olmesartan Medoxomil', 'tradeNames_string': 'Benicar, Olmesartan medoxomil, Olmetec', 'drugSynonyms_string': 'CS-866, NSC-758924, Olmesartan medoxomil', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Diabetic Nephropathy (EFO_0000401), Stroke (EFO_000071... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1955 | Q17 | What gene does the drug Amifampridine target? | The drug Amifampridine targets 40 genes: KCNB1, KCND2, KCNA7, KCNG3, KCNA4, KCNQ1, KCNQ3, KCNA1, KCNC4, KCNS1, KCNG2, KCNA6, KCNV2, KCNA5, KCNH2, KCNS3, KCNQ4, KCND3, KCNG1, KCNB2, KCNH6, KCNC3, KCNG4, KCNF1, KCNH8, KCNS2, KCNA3, KCNQ2, KCNH4, KCNA10, KCNC2, KCNC1, KCNH1, KCNH3, KCNV1, KCNQ5, KCND1, KCNA2, KCNH7 and KC... | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3435', 'drugName': 'Amifampridine Phosphate', 'tradeNames_string': 'Firdapse', 'drugSynonyms_string': '3,4-DAPP, Amifampridine phosphate, DAPP, Zenas', 'linkedDiseasesDrug_string': 'Myasthenia Gravis (EFO_0004991), Brugada Syndrome (MONDO_0015263), Spinal Muscular Atrophy (EFO_0008525), Mu... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1218 | Q17 | What gene does the drug Brimonidine Tartrate target? | The drug Brimonidine Tartrate targets 3 genes: ADRA2A, ADRA2C and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4923', 'drugName': 'Brimonidine Tartrate', 'tradeNames_string': 'Alphagan, Alphagan p, Brimonidine tartrate, Brymont, Lumify, Mirvaso, Qoliana', 'drugSynonyms_string': 'AGN 190342-LF, AGN-190342-LF, AGN-190342LF, Brimonidine d-tartrate, Brimonidine tartrate, Bromoxidine tartrate, Cd-07805,... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1680 | Q17 | What gene does the drug Carboprost Tromethamine target? | The drug Carboprost Tromethamine targets the gene PTGFR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2928', 'drugName': 'Carboprost Tromethamine', 'tradeNames_string': 'Hemabate', 'drugSynonyms_string': 'Carboprost trometamol, Carboprost trometanol, Carboprost tromethamine, Carboprost tromethamine salt, U-32,921E, U-32921E', 'linkedDiseasesDrug_string': 'Postpartum Hemorrhage (EFO_0009579... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1975 | Q17 | What gene does the drug Metoclopramide target? | The drug Metoclopramide targets 3 genes: HTR3A, HTR4 and DRD2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3506', 'drugName': 'Metoclopramide', 'tradeNames_string': '', 'drugSynonyms_string': 'Clopra, Clopra-"Yellow", Elieten, Maxolon, Methoxyclopramide, Metoclopramide, Reglan, Terperan', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Orthostatic Hypotension (EFO_0005252), Chemotherapy-I... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.213 | Q17 | What gene does the drug Apalutamide target? | The drug Apalutamide targets the gene AR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_6164', 'drugName': 'Apalutamide', 'tradeNames_string': 'Erleada', 'drugSynonyms_string': 'ARN-509, Apalutamide, Arn-509, JNJ-56021927', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Prostate Cancer (MONDO_0008315), Neoplasm (EFO_0000616), Salivary Gland Neoplasm (EFO_0003826), Live... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1534 | Q17 | What gene does the drug Argatroban target? | The drug Argatroban targets the gene F2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2622', 'drugName': 'Argatroban', 'tradeNames_string': 'Acova, Argatroban, Argatroban in dextrose, Argatroban in sodium chloride', 'drugSynonyms_string': 'Argatroban, Argatroban anhydrous, Argatroban hydrate, Argatroban monohydrate, Argipidine, DK-7419, GN-1600, GN1600, MCI-9038, MD-805', '... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1135 | Q17 | What gene does the drug Butorphanol Tartrate target? | The drug Butorphanol Tartrate targets 2 genes: OPRK1 and OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1672', 'drugName': 'Butorphanol Tartrate', 'tradeNames_string': 'Butorphanol tartrate, Butorphanol tartrate preservative free, Stadol, Stadol ns, Stadol preservative free, Torbugesic, Torbutrol', 'drugSynonyms_string': 'Butorphanol tartrate, Butorphanol tartrate civ, Dolorex, LEVO-BC-2627 ... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.131 | Q17 | What gene does the drug Camicinal target? | The drug Camicinal is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene MLNR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4697', 'drugName': 'Camicinal', 'tradeNames_string': '', 'drugSynonyms_string': 'Camicinal, GSK-962040, GSK-962040B, GSK962040, GSK962040B, Gsk962040', 'linkedDiseasesDrug_string': 'Gastroparesis (EFO_1000948)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False,... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.819 | Q17 | What gene does the drug Vinflunine target? | The drug Vinflunine targets 15 genes: TUBB, TUBA4A, TUBA3E, TUBB3, TUBB4B, TUBB2A, TUBA1A, TUBA1C, TUBB1, TUBB2B, TUBB8, TUBB6, TUBB4A, TUBA3C and TUBA1B. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_974', 'drugName': 'Vinflunine', 'tradeNames_string': '', 'drugSynonyms_string': 'Vinflunine', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Head And Neck Carcinoma (MONDO_0002038), Urogenital Neoplasm (EFO_0003863), Breast Cancer (MONDO_0007254), Penile Neoplasm (EFO_1001094), Smal... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1282 | Q17 | What gene does the drug Racecadotril target? | The drug Racecadotril targets the gene MME. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5090', 'drugName': 'Racecadotril', 'tradeNames_string': 'Hidrasec', 'drugSynonyms_string': 'Acetorphan, NSC-759828, Racecadotril, Tiorfan, Tiorfix', 'linkedDiseasesDrug_string': 'Diarrhea (HP_0002014), Diarrhea, Infantile (EFO_1001306)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1872 | Q17 | What gene does the drug Sibutramine Hydrochloride target? | The drug Sibutramine Hydrochloride targets 3 genes: SLC6A4, SLC6A2 and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2809', 'drugName': 'Sibutramine Hydrochloride', 'tradeNames_string': 'Meridia', 'drugSynonyms_string': 'BTS 54524, BTS-54524, NSC-758928, Sibutramine hcl, Sibutramine hydrochloride, Sibutramine hydrochloride civ, Sibutramine hydrochloride hydrate, Sibutramine hydrochloride monohydrate', 'l... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.438 | Q17 | What gene does the drug Triptorelin target? | The drug Triptorelin targets the gene GNRHR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4710', 'drugName': 'Triptorelin Pamoate', 'tradeNames_string': 'Trelstar, Triptodur kit', 'drugSynonyms_string': 'Salvacyl, Triptorelin (as embonate), Triptorelin embonate, Triptorelin pamoate', 'linkedDiseasesDrug_string': 'Central Precocious Puberty (EFO_0009029), Prostate Cancer (MONDO_... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.417 | Q17 | What gene does the drug Lanadelumab target? | The drug Lanadelumab targets the gene KLKB1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3309', 'drugName': 'Lanadelumab', 'tradeNames_string': 'Takhzyro', 'drugSynonyms_string': 'DX-2930, Lanadelumab, Lanadelumab (shp643), Lanadelumab flyo, Lanadelumab-flyo, SHP-643, Tak-743', 'linkedDiseasesDrug_string': 'Covid-19 (MONDO_0100096), Angioedema (EFO_0005532), Injury (EFO_000054... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1504 | Q17 | What gene does the drug Nemiralisib target? | The drug Nemiralisib is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene PIK3CD. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2005', 'drugName': 'Gsk-2269557', 'tradeNames_string': '', 'drugSynonyms_string': 'GSK-2269557, GSK2269557, Gsk-2269557, Nemiralisib hydrochloride', 'linkedDiseasesDrug_string': 'Asthma (MONDO_0004979), Chronic Obstructive Pulmonary Disease (EFO_0000341)', 'yearOfFirstApproval': 0, 'maxCli... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.234 | Q17 | What gene does the drug Erlosamide target? | The drug Erlosamide targets 10 genes: SCN1A, SCN9A, SCN7A, SCN8A, SCN11A, SCN10A, SCN2A, SCN5A, SCN4A and SCN3A. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4004', 'drugName': 'Erlosamide', 'tradeNames_string': 'Lacosamide, Vimpat', 'drugSynonyms_string': '(r)-lacosamide 1, ADD 243037, ADD-243037, Erlosamide, Lacosamide, Lacosamide cv, SPM 927, SPM-927', 'linkedDiseasesDrug_string': 'Migraine Disorder (MONDO_0005277), Central Nervous System Ca... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1708 | Q17 | What gene does the drug Moc31-Pe target? | The drug Moc31-Pe is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene EPCAM. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1481', 'drugName': 'Moc31-Pe', 'tradeNames_string': '', 'drugSynonyms_string': 'MOC31-PE, Moc31-pe', 'linkedDiseasesDrug_string': 'Carcinoma (EFO_0000313)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False, 'newLinkedTargets_string': 'EPCAM (ENSG00000119888)', ... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.895 | Q17 | What gene does the drug Prednicarbate target? | The drug Prednicarbate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3323', 'drugName': 'Prednicarbate', 'tradeNames_string': 'Dermatop, Dermatop e emollient, Prednicarbate', 'drugSynonyms_string': 'HOE 777, HOE-777, LAS-189961, LAS-41003 COMPONENT PREDNICARBATE, LAS189961, NSC-760042, Prednicarbate, S 77 0777, S-77 0777, S-77-0777, S-770777', 'linkedDiseas... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1625 | Q17 | What gene does the drug Odronextamab target? | The drug Odronextamab is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 4 genes: MS4A1, CD3E, CD3G and CD3D | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1602', 'drugName': 'Odronextamab', 'tradeNames_string': '', 'drugSynonyms_string': 'Odronextamab, REGN-1979, REGN1979, Regn-1979, Regn1979', 'linkedDiseasesDrug_string': 'Neoplasm Of Mature B-Cells (EFO_0000096), Chronic Lymphocytic Leukemia (EFO_0000095), Lymphoma (EFO_0000574)', 'yearOfF... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.699 | Q17 | What gene does the drug Oxyphenonium Bromide target? | The drug Oxyphenonium Bromide targets 2 genes: CHRM1 and CHRM3. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1163', 'drugName': 'Oxyphenonium Bromide', 'tradeNames_string': 'Antrenyl', 'drugSynonyms_string': 'Antrenil, BA-5473, C-5473, NSC-759248, Oxifenon, Oxyfenon, Oxyphenon, Oxyphenonium bromide, Spasmodin, Spasmophen', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1982, 'maxClinical... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1769 | Q17 | What gene does the drug Bortezomib target? | The drug Bortezomib targets 38 genes: PSMD6, PSMC5, PSMB11, PSMA4, PSMC6, PSMC2, PSMB2, PSMA6, PSMA2, PSMD13, PSMB9, ADRM1, PSMD2, PSMB8, PSMB4, PSMD11, SEM1, PSMB10, PSMD14, PSMA3, PSMB1, PSMD4, PSMB3, PSMA5, PSMD12, PSMB6, PSMD7, PSMB5, PSMD8, PSMD1, PSMC4, PSMA1, PSMA8, PSMC3, PSMC1, PSMA7, PSMD3 and PSMB7. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_559', 'drugName': 'Bortezomib', 'tradeNames_string': 'Velcade', 'drugSynonyms_string': 'Bortezomib, Bortezomib accord, Bortezomib hydrate, LDP-341, NSC-681239, PS-341, Velcade', 'linkedDiseasesDrug_string': "Multiple Myeloma (EFO_0001378), Papillary Thyroid Carcinoma (EFO_0000641), Bronchi... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.301 | Q17 | What gene does the drug Etretinate target? | The drug Etretinate targets 6 genes: RARG, RARA, RARB, RXRB, RXRG and RXRA. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_343', 'drugName': 'Etretinate', 'tradeNames_string': 'Tegison, Tigason', 'drugSynonyms_string': 'Acitretin related compound b, Ethyl etrinoate, Etretinate, NSC-297936, RO 10-9359, RO-10-9359, RO-109359', 'linkedDiseasesDrug_string': 'Psoriasis (EFO_0000676)', 'yearOfFirstApproval': 1986, '... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1399 | Q17 | What gene does the drug Alclofenac target? | The drug Alclofenac targets the gene PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3320', 'drugName': 'Alclofenac', 'tradeNames_string': 'Mervan', 'drugSynonyms_string': 'Alclofenac, W 7320', 'linkedDiseasesDrug_string': 'Rheumatic Disease (EFO_0005755)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newLinkedTargets_string': 'PTGS1 (ENSG... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1987 | Q17 | What gene does the drug Mecasermin Rinfabate target? | The drug Mecasermin Rinfabate targets the gene IGF1R. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_672', 'drugName': 'Mecasermin Rinfabate', 'tradeNames_string': 'Iplex, Somatokine', 'drugSynonyms_string': 'Mecasermin Rinfabate Recombinant, Mecasermin rinfabate, Mecasermin rinfabate recombinant, RHIGF-I/RHIGFBP-3', 'linkedDiseasesDrug_string': 'Myotonic Dystrophy (MONDO_0016107), Steine... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.102 | Q17 | What gene does the drug Tazarotene target? | The drug Tazarotene targets 3 genes: RARB, RARA and RARG. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5124', 'drugName': 'Tazarotene', 'tradeNames_string': 'Arazlo, Avage, Fabior, Tazorac, Zorac', 'drugSynonyms_string': 'AGN 190168, AGN-190168, Idp-123, Tazarotene', 'linkedDiseasesDrug_string': 'Psoriasis (EFO_0000676), Genetic Hypopigmentation Of The Skin (Orphanet_183469), Skin Carcinoma... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.831 | Q17 | What gene does the drug Saxagliptin target? | The drug Saxagliptin targets the gene DPP4. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_6010', 'drugName': 'Saxagliptin', 'tradeNames_string': '', 'drugSynonyms_string': 'BMS-477118, BMS-477118-11, Saxagliptin', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Polycystic Ovary Syndrome (EFO_0000660), Abnormal Glucose Tolerance (EFO_0002546), Acute Myocardial Inf... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
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