uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
values | bio_category stringclasses 14
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|---|---|---|---|---|---|---|---|---|
Q17.909 | Q17 | What gene does the drug Tafasitamab target? | The drug Tafasitamab targets the gene CD19. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3753', 'drugName': 'Tafasitamab', 'tradeNames_string': 'Monjuvi, Monjuvi (tafasitamab-cxix) for injection', 'drugSynonyms_string': 'MOR-00208, MOR00208, MOR208, Mor-208, Mor00208, Tafasitamab, Tafasitamab cxix, Tafasitamab-cxix, XmAb5574, Xmab-5574, Xmab5574', 'linkedDiseasesDrug_string': ... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.679 | Q17 | What gene does the drug Lumasiran target? | The drug Lumasiran targets the gene HAO1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1382', 'drugName': 'Lumasiran', 'tradeNames_string': '', 'drugSynonyms_string': 'AD-65585, ALN-65585, ALN-G01, ALN-GO1, Lumasiran', 'linkedDiseasesDrug_string': 'Primary Hyperoxaluria (MONDO_0002474), Nephrolithiasis (EFO_0004253), Primary Hyperoxaluria Type 1 (MONDO_0009823)', 'yearOfFirs... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.261 | Q17 | What gene does the drug Finasteride target? | The drug Finasteride targets the gene SRD5A2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5461', 'drugName': 'Finasteride', 'tradeNames_string': 'Aindeem, Finasteride, Propecia, Proscar, Prostide', 'drugSynonyms_string': 'Finasteride, MK-906, NSC-741485, NSC-759318', 'linkedDiseasesDrug_string': 'Androgenetic Alopecia (EFO_0004191), Hyperplasia (EFO_0000536), Hypogonadism (MOND... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.851 | Q17 | What gene does the drug Rocuronium target? | The drug Rocuronium targets 5 genes: CHRNB1, CHRNA1, CHRND, CHRNE and CHRNG. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1958', 'drugName': 'Rocuronium', 'tradeNames_string': '', 'drugSynonyms_string': 'Rocuronium, Rocuronium cation, Rocuronium ion', 'linkedDiseasesDrug_string': 'Pancreatic Carcinoma (EFO_0002618), Cardiac Arrest (EFO_0009492), Prostate Cancer (MONDO_0008315), Pain (EFO_0003843), Back Pain (... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.874 | Q17 | What gene does the drug Carbinoxamine target? | The drug Carbinoxamine targets the gene HRH1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4593', 'drugName': 'Carbinoxamine Maleate', 'tradeNames_string': 'Carbinoxamine maleate, Clistin, Davenol, Karbinal er', 'drugSynonyms_string': 'Carbinoxamine maleate, NSC-62362', 'linkedDiseasesDrug_string': 'Allergic Conjunctivitis (EFO_0007141), Rhinitis, Allergic, Perennial (EFO_100141... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1564 | Q17 | What gene does the drug Ing-1 target? | The drug Ing-1 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene EPCAM. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5093', 'drugName': 'Ing-1', 'tradeNames_string': '', 'drugSynonyms_string': 'HEMAB, ING-1, Ing-1', 'linkedDiseasesDrug_string': 'Adenocarcinoma (EFO_0000228)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'newLinkedTargets_string': 'EPCAM (ENSG00000119888)... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.141 | Q17 | What gene does the drug Troglitazone target? | The drug Troglitazone targets the gene PPARG. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1190', 'drugName': 'Troglitazone', 'tradeNames_string': 'Prelay, Rezulin, Romozin', 'drugSynonyms_string': 'CI-991, CS-045, GR-92132X, GR92132X, Rezulin, Troglitazone', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Sarcoma (EFO_0000691)', 'yearOfFirstApproval': 1997, 'maxC... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.900 | Q17 | What gene does the drug Ruxolitinib Phosphate target? | The drug Ruxolitinib Phosphate targets 2 genes: JAK1 and JAK2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1727', 'drugName': 'Ruxolitinib Phosphate', 'tradeNames_string': 'Jakafi, Opzelura', 'drugSynonyms_string': 'INCB-018424 PHOSPHATE, INCB-018424 SALT, INCB-18424 PHOSPHATE, INCB018424 PHOSPHATE, INCB018424 SALT, Opzelura, Ruxolitinib (as phosphate), Ruxolitinib monophosphate, Ruxolitinib ph... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1839 | Q17 | What gene does the drug Oregovomab target? | The drug Oregovomab is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene MUC16. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3687', 'drugName': 'Oregovomab', 'tradeNames_string': 'Ovarex', 'drugSynonyms_string': 'Oregovamab, Oregovomab, mAb-B43.13', 'linkedDiseasesDrug_string': 'Ovarian Carcinoma (EFO_0001075), Fallopian Tube Cancer (MONDO_0002158), Ovarian Neoplasm (EFO_0003893), Peritoneum Cancer (MONDO_000208... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.555 | Q17 | What gene does the drug Chlorpheniramine target? | The drug Chlorpheniramine targets the gene HRH1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_6213', 'drugName': 'Dexchlorpheniramine Maleate', 'tradeNames_string': 'Dexchlorpheniramine maleate, Mylaramine, Polaramine', 'drugSynonyms_string': 'Chlorpheniramine d-form maleate, Chlorpheniramine maleate, (s)-, D-chlorpheniramine maleate, Dexchlorpheniramine maleate, NSC-759156', 'link... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.323 | Q17 | What gene does the drug Ethchlorvynol target? | The drug Ethchlorvynol targets 16 genes: GABRG2, GABRE, GABRA4, GABRQ, GABRD, GABRA3, GABRP, GABRA5, GABRG3, GABRB2, GABRB3, GABRG1, GABRA2, GABRB1, GABRA6 and GABRA1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3295', 'drugName': 'Ethchlorvynol', 'tradeNames_string': 'Ethchlorvynol, Placidyl', 'drugSynonyms_string': 'Alvinol, Arvynol, Ethchlorvynol, Ethchlorvynol civ, NSC-30372, Normoson, Nostel, Roeridorm, Serenesil, Serensil', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1961, 'maxCl... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1854 | Q17 | What gene does the drug Batoprotafib target? | The drug Batoprotafib is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene PTPN11. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_6363', 'drugName': 'Batoprotafib', 'tradeNames_string': '', 'drugSynonyms_string': 'Batoprotafib, Ptpn11 inhibitor tno155, Shp2 inhibitor tno155, TNO-155, TNO155, Tno 155, Tno-155, Tno155', 'linkedDiseasesDrug_string': 'Neoplasm (EFO_0000616)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPh... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1235 | Q17 | What gene does the drug Menthol target? | The drug Menthol targets 2 genes: TRPM8 and TRPA1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5721', 'drugName': 'Menthol', 'tradeNames_string': "Aqua-cool, Aquasoothe, Arjun, Catarrh, Dermacool, Fisherman's friend lozenges, Halls, Karvol, Lockets, Meggezones, Muirs, Therapeutic mineral ice, Tixylix decongestant inh, Vocalzone", 'drugSynonyms_string': 'Dl-menthol, FEMA NO. 2665, Me... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1726 | Q17 | What gene does the drug Abt-925 target? | The drug Abt-925 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene DRD3. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3906', 'drugName': 'Abt-925', 'tradeNames_string': '', 'drugSynonyms_string': 'A-437203, Abt-925', 'linkedDiseasesDrug_string': 'Schizophrenia (MONDO_0005090)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'newLinkedTargets_string': 'DRD3 (ENSG00000151577)... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.564 | Q17 | What gene does the drug Clothiapine target? | The drug Clothiapine targets 9 genes: DRD4, HTR3D, HTR3C, HTR2A, HTR2B, HTR3E, HTR3B, HTR2C and HTR3A. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2386', 'drugName': 'Clothiapine', 'tradeNames_string': '', 'drugSynonyms_string': 'Clothiapine, Clotiapine, Entumin, HF-2159', 'linkedDiseasesDrug_string': 'Psychosis (EFO_0005407)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newLinkedTargets_string': 'H... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.142 | Q17 | What gene does the drug Ozanimod target? | The drug Ozanimod targets the gene S1PR1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1976', 'drugName': 'Ozanimod', 'tradeNames_string': '', 'drugSynonyms_string': 'Ozanimod, RPC-1063, RPC1063', 'linkedDiseasesDrug_string': "Crohn'S Disease (EFO_0000384), Multiple Sclerosis (MONDO_0005301), Liver Disease (EFO_0001421), Covid-19 (MONDO_0100096), Ulcerative Colitis (EFO_0000... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1736 | Q17 | What gene does the drug Eslicarbazepine Acetate target? | The drug Eslicarbazepine Acetate targets 10 genes: SCN1A, SCN9A, SCN7A, SCN8A, SCN11A, SCN10A, SCN2A, SCN5A, SCN4A and SCN3A. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4666', 'drugName': 'Eslicarbazepine Acetate', 'tradeNames_string': 'Aptiom, Erelib, Pazzul, Stedesa, Zebinix', 'drugSynonyms_string': 'BIA 2-093, BIA-2-093, BIA-2093, Eslicarbazepine acetate, SEP - 0002093, SEP-0002093', 'linkedDiseasesDrug_string': 'Diabetic Neuropathy (EFO_1000783), Post... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.537 | Q17 | What gene does the drug Gsk-1292263 target? | The drug Gsk-1292263 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene GPR119. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5541', 'drugName': 'Gsk-1292263', 'tradeNames_string': '', 'drugSynonyms_string': 'GSK-1292263, GSK-1292263A, GSK-263A, GSK1292263, Gsk 1292263, Gsk-1292263, Gsk1292263', 'linkedDiseasesDrug_string': 'Type 2 Diabetes Mellitus (MONDO_0005148), Disorder Of Lipid Metabolism (Orphanet_309005)'... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.227 | Q17 | What gene does the drug Suvorexant target? | The drug Suvorexant targets 2 genes: HCRTR2 and HCRTR1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5935', 'drugName': 'Suvorexant', 'tradeNames_string': 'Belsomra', 'drugSynonyms_string': 'MK-4305, MK4305, Suvorexant', 'linkedDiseasesDrug_string': 'Alzheimer Disease (MONDO_0004975), Sleep Apnea (EFO_0003877), Opioid Use Disorder (EFO_0010702), Smoking Cessation (EFO_0004319), Sleep Diso... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.730 | Q17 | What gene does the drug Indomethacin Sodium target? | The drug Indomethacin Sodium targets 2 genes: PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4252', 'drugName': 'Indomethacin Sodium', 'tradeNames_string': 'Indocin, Indomethacin sodium', 'drugSynonyms_string': 'Indometacin sodium, Indometacin sodium hydrate, Indometacin sodium trihydrate, Indomethacin sodium, Indomethacin sodium anhydrous, Indomethacin sodium salt trihydrate, Ind... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.793 | Q17 | What gene does the drug Flurbiprofen Sodium target? | The drug Flurbiprofen Sodium targets 2 genes: PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2737', 'drugName': 'Flurbiprofen Sodium', 'tradeNames_string': 'Ansaid, Flurbiprofen sodium, Occufen, Ocufen, Zepolas', 'drugSynonyms_string': 'Flurbiprofen sodium, Flurbiprofen sodium anhydrous, Flurbiprofen sodium dihydrate', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1986, ... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1718 | Q17 | What gene does the drug Doxylamine target? | The drug Doxylamine targets the gene HRH1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3456', 'drugName': 'Doxylamine Succinate', 'tradeNames_string': 'Decapryn, Doxy-sleep-aid, Doxylamine succinate, Unisom', 'drugSynonyms_string': 'Alsodorm, Donormil, Donormyl, Dormidina, Doxylamine hydrogen succinate, Doxylamine succinate, Gittalun, Hoggar n, Meraprina, NSC-74772', 'linked... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.994 | Q17 | What gene does the drug Tirofiban target? | The drug Tirofiban targets 2 genes: ITGB3 and ITGA2B. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2127', 'drugName': 'Tirofiban', 'tradeNames_string': '', 'drugSynonyms_string': 'Aggrastat, Agrastat, L-700462, MK-383, Tirofiban', 'linkedDiseasesDrug_string': 'Recurrent Thrombophlebitis (HP_0004419), Coronary Artery Disease (EFO_0001645), Ischemic Stroke (HP_0002140), Viral Pneumonia (E... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.415 | Q17 | What gene does the drug Betaine target? | The drug Betaine targets 2 genes: BHMT2 and BHMT. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3565', 'drugName': 'Betaine', 'tradeNames_string': 'Cystadane', 'drugSynonyms_string': 'Abromine, Betaine, Betaine anhydrous, Betaine, anhydrous, Cystadane, FEMA NO. 4223, NSC-166511', 'linkedDiseasesDrug_string': 'Unipolar Depression (EFO_0003761), Male Infertility (EFO_0004248), Xerostom... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.329 | Q17 | What gene does the drug Glembatumumab Vedotin target? | The drug Glembatumumab Vedotin is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 16 genes: TUBB, TUBA4A, TUBA3E, TUBB3, GPNMB, TUBB4B, TUBB2A, TUBA1A, TUBA1C, TUBB1, TUBB2B, TUBB8, TUBB6, TUBB4A, TUBA3C and TUBA1B | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_6314', 'drugName': 'Glembatumumab Vedotin', 'tradeNames_string': '', 'drugSynonyms_string': 'CDX-011, CR-011-VCMMAE, Glembatumumab vedotin', 'linkedDiseasesDrug_string': 'Melanoma (EFO_0000756), Squamous Cell Lung Carcinoma (EFO_0000708), Osteosarcoma (EFO_0000637), Breast Cancer (MONDO_00... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1098 | Q17 | What gene does the drug Docetaxel target? | The drug Docetaxel targets 15 genes: TUBB, TUBA4A, TUBA3E, TUBB3, TUBB4B, TUBB2A, TUBA1A, TUBA1C, TUBB1, TUBB2B, TUBB8, TUBB6, TUBB4A, TUBA3C and TUBA1B. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1267', 'drugName': 'Docetaxel', 'tradeNames_string': '', 'drugSynonyms_string': 'RP-56976, Taxotere', 'linkedDiseasesDrug_string': 'Ovarian Carcinoma (EFO_0001075), Multiple Myeloma (EFO_0001378), Malignant Colon Neoplasm (MONDO_0021063), Cervical Adenocarcinoma (EFO_0001416), Inflammatory... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.303 | Q17 | What gene does the drug Andolast target? | The drug Andolast is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene KCNMA1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5782', 'drugName': 'Andolast', 'tradeNames_string': '', 'drugSynonyms_string': 'Andolast, Cr2039', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'newLinkedTargets_string': 'KCNMA1 (ENSG00000156113)', 'numberLinkedTargets': 1... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1259 | Q17 | What gene does the drug Ranitidine Hydrochloride target? | The drug Ranitidine Hydrochloride targets the gene HRH2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1617', 'drugName': 'Ranitidine Hydrochloride', 'tradeNames_string': 'Azantac, Dumoran, Gavilast, Gavilast-p, Histac, Raciran 150, Raciran 300, Ranicalm, Raniplex, Ranitic, Ranitidine hydrochloride, Ranitil, Rantec, Ranzac, Vivatak, Zaedoc 150, Zaedoc 300, Zantac, Zantac 150, Zantac 25, Zan... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1996 | Q17 | What gene does the drug Quinapril Hydrochloride target? | The drug Quinapril Hydrochloride targets the gene ACE. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1269', 'drugName': 'Quinapril Hydrochloride', 'tradeNames_string': 'Accupril, Accupro, Quinapril hydrochloride, Quinil', 'drugSynonyms_string': 'CI 906, CI-906, NSC-758222, Quinapril hcl, Quinapril hydrochloride', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Stroke (EFO_0... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.26 | Q17 | What gene does the drug Trimethaphan target? | The drug Trimethaphan targets 2 genes: CHRNB4 and CHRNA3. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4467', 'drugName': 'Trimethaphan', 'tradeNames_string': '', 'drugSynonyms_string': 'Trimetaphan, Trimethaphan, Trimethaphan cation, Trimethaphan ion', 'linkedDiseasesDrug_string': 'Insulin Resistance (EFO_0002614), Hypertension (EFO_0000537)', 'yearOfFirstApproval': 1982, 'maxClinicalTrial... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1860 | Q17 | What gene does the drug Drospirenone target? | The drug Drospirenone targets 2 genes: NR3C2 and PGR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1555', 'drugName': 'Drospirenone', 'tradeNames_string': 'Angeliq, Slynd', 'drugSynonyms_string': 'Drospirenone, NSC-760103, ZK 30595, ZK-30595', 'linkedDiseasesDrug_string': 'Polycystic Ovary Syndrome (EFO_0000660), Binge Eating (EFO_0005924), Dysmenorrhea (HP_0100607), Acne (EFO_0003894),... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.721 | Q17 | What gene does the drug Methyltestosterone target? | The drug Methyltestosterone targets the gene AR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2216', 'drugName': 'Methyltestosterone', 'tradeNames_string': 'Android 10, Android 25, Android 5, Metandren, Methitest, Methyltestosterone, Oreton, Oreton methyl, Perandren, Plex hormone, Potensan fte, Testovis, Testred, Virilon', 'drugSynonyms_string': '17-methyltestosterone, CDB-110, L 5... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.996 | Q17 | What gene does the drug Tirzepatide target? | The drug Tirzepatide targets 2 genes: GLP1R and GIPR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5134', 'drugName': 'Tirzepatide', 'tradeNames_string': 'Mounjaro', 'drugSynonyms_string': 'LY-3298176, LY3298176, Ly3298176, Mounjaro, Tirzepatide', 'linkedDiseasesDrug_string': 'Type 2 Diabetes Mellitus (MONDO_0005148), Obesity (EFO_0001073), Non-Alcoholic Steatohepatitis (EFO_1001249)', ... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.196 | Q17 | What gene does the drug Pexidartinib target? | The drug Pexidartinib targets 3 genes: CSF1R, FLT3 and KIT. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4379', 'drugName': 'Pexidartinib Hydrochloride', 'tradeNames_string': 'Turalio', 'drugSynonyms_string': 'FP-113, PLX-3397 HCL, PLX3397 HCl, Pexidartinib hydrochloride', 'linkedDiseasesDrug_string': 'Tenosynovial Giant Cell Tumor (EFO_1000562)', 'yearOfFirstApproval': 2019, 'maxClinicalTria... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.446 | Q17 | What gene does the drug Carprofen target? | The drug Carprofen targets the gene PTGS2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_354', 'drugName': 'Carprofen', 'tradeNames_string': 'Rimadyl', 'drugSynonyms_string': 'Carprofen, Carprofen for veterinary use, NSC-297935, RO 20-5720/000, Ro-205720000', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1987, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newL... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.579 | Q17 | What gene does the drug Sodelglitazar target? | The drug Sodelglitazar is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 3 genes: PPARG, PPARD and PPARA | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5445', 'drugName': 'Sodelglitazar', 'tradeNames_string': '', 'drugSynonyms_string': 'GW-677954, GW677954, Sodelglitazar', 'linkedDiseasesDrug_string': 'Metabolic Syndrome (EFO_0000195), Type 2 Diabetes Mellitus (MONDO_0005148)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIs... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.955 | Q17 | What gene does the drug Irinotecan Sucrosofate target? | The drug Irinotecan Sucrosofate is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene TOP1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2149', 'drugName': 'Irinotecan Sucrosofate', 'tradeNames_string': '', 'drugSynonyms_string': 'Irinotecan sucrosofate, MM-398, PEP-02', 'linkedDiseasesDrug_string': 'Pancreatic Carcinoma (EFO_0002618), Cancer (MONDO_0004992), Neoplasm (EFO_0000616)', 'yearOfFirstApproval': 0, 'maxClinicalTr... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.509 | Q17 | What gene does the drug Becocalcidiol target? | The drug Becocalcidiol is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene VDR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5125', 'drugName': 'Becocalcidiol', 'tradeNames_string': '', 'drugSynonyms_string': '2MBisP, Becocalcidiol, DP-006, DP006, QRX 101, QRX-101, Qrx-101', 'linkedDiseasesDrug_string': 'Psoriasis (EFO_0000676)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'new... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.612 | Q17 | What gene does the drug Levobupivacaine target? | The drug Levobupivacaine targets the gene SCN4A. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4768', 'drugName': 'Levobupivacaine Hydrochloride', 'tradeNames_string': 'Chirocaine, Levobupivac', 'drugSynonyms_string': 'Bupivacaine (-)-form hydrochloride, CHIROCAINE, Levobupivacaine hcl, Levobupivacaine hydrochloride', 'linkedDiseasesDrug_string': 'Pregnancy (EFO_0002950), Pain (EFO_... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1864 | Q17 | What gene does the drug Remimazolam Besylate target? | The drug Remimazolam Besylate targets 16 genes: GABRG2, GABRE, GABRA4, GABRQ, GABRD, GABRA3, GABRP, GABRA5, GABRG3, GABRB2, GABRB3, GABRG1, GABRA2, GABRB1, GABRA6 and GABRA1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1800', 'drugName': 'Remimazolam Besylate', 'tradeNames_string': 'Byfavo', 'drugSynonyms_string': 'BIPRAZINE PF, CNS 7056 besylate, CNS 7056B, CNS-7056 BESYLATE, CNS-7056B, GW-502056X, GW502056X, ONO-2745BS, ONO-IN-251, RF-10007, RF10007, Remimazolam besilate, Remimazolam besylate, SP148.5'... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1725 | Q17 | What gene does the drug Atomoxetine target? | The drug Atomoxetine targets the gene SLC6A2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4562', 'drugName': 'Atomoxetine', 'tradeNames_string': '', 'drugSynonyms_string': 'Atomoxetine, Strattera', 'linkedDiseasesDrug_string': 'Autism (EFO_0003758), Cancer (MONDO_0004992), Alzheimer Disease (MONDO_0004975), Orthostatic Hypotension (EFO_0005252), Substance Abuse (MONDO_0002491),... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1885 | Q17 | What gene does the drug Larotrectinib Sulfate target? | The drug Larotrectinib Sulfate targets 3 genes: NTRK1, NTRK3 and NTRK2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3998', 'drugName': 'Larotrectinib Sulfate', 'tradeNames_string': 'Vitrakvi', 'drugSynonyms_string': 'ARRY-470 SULFATE, LOXO-101 sulfate, Larotrectinib sulfate', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Metastasis (EFO_0009708), Neoplasm (EFO_0000616)', 'yearOfFirstApproval': 2... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.853 | Q17 | What gene does the drug Nintedanib target? | The drug Nintedanib targets 9 genes: FGFR2, FGFR3, FLT4, FGFR4, FLT1, KDR, FGFR1, PDGFRB and PDGFRA. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4525', 'drugName': 'Nintedanib Esylate', 'tradeNames_string': 'Ofev', 'drugSynonyms_string': 'Nintedanib esilate, Nintedanib esylate, Nintedanib ethanesulfonate', 'linkedDiseasesDrug_string': 'Idiopathic Pulmonary Fibrosis (EFO_0000768), Systemic Scleroderma (EFO_0000717)', 'yearOfFirstApp... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.4 | Q17 | What gene does the drug Dipivefrin Hydrochloride target? | The drug Dipivefrin Hydrochloride targets 9 genes: ADRA2A, ADRB1, ADRA2C, ADRA1A, ADRA1D, ADRA1B, ADRB3, ADRA2B and ADRB2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1692', 'drugName': 'Dipivefrin Hydrochloride', 'tradeNames_string': 'Akpro, Dipivefrin hydrochloride, Propine', 'drugSynonyms_string': 'Dipivefrin hcl, Dipivefrin hydrochloride, Dipivefrine hydrochloride', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1980, 'maxClinicalTrialPhase... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1569 | Q17 | What gene does the drug Nortriptyline Hydrochloride target? | The drug Nortriptyline Hydrochloride targets 2 genes: SLC6A4 and SLC6A2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5991', 'drugName': 'Nortriptyline Hydrochloride', 'tradeNames_string': 'Aventyl, Aventyl hydrochloride, Nortriptyline hydrochloride, Pamelor, Psychostyl', 'drugSynonyms_string': '38489, NSC-169453, Nortriptyline hcl, Nortriptyline hydrochloride', 'linkedDiseasesDrug_string': 'Psoriasis (EF... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1461 | Q17 | What gene does the drug Alprostadil target? | The drug Alprostadil targets 2 genes: PTGER2 and PTGER1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4035', 'drugName': 'Alprostadil', 'tradeNames_string': 'Alprostadil, Caverject, Caverject impulse, Edex, Prostin, Prostin vr, Prostin vr pediatric, Viridal 10, Viridal 20, Viridal 5, Viridal duo, Vitaros', 'drugSynonyms_string': 'Alprostadil, NSC-165559, ONO-1608, Pge1, Prostaglandin e1, U... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.473 | Q17 | What gene does the drug Anastrozole target? | The drug Anastrozole targets the gene CYP19A1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3640', 'drugName': 'Anastrozole', 'tradeNames_string': 'Anastrozole, Arimidex, Nastrosa', 'drugSynonyms_string': 'Anastrozole, Arimidex, ICI D1033, ICI-D1033, NSC-719344, NSC-759855, Rvg-106400, ZD-1033, ZD1033', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Pulmonary Arterial Hype... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.325 | Q17 | What gene does the drug Inotuzumab Ozogamicin target? | The drug Inotuzumab Ozogamicin targets the gene CD22. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_6318', 'drugName': 'Inotuzumab Ozogamicin', 'tradeNames_string': 'Besponsa', 'drugSynonyms_string': 'CMC-544, Inotuzumab ozogamicin, PF-05208773, WAY-207294, WAY-207294 CMC-544', 'linkedDiseasesDrug_string': 'Non-Hodgkins Lymphoma (EFO_0005952), Follicular Lymphoma (MONDO_0018906), Neoplas... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.6 | Q17 | What gene does the drug Trimipramine Maleate target? | The drug Trimipramine Maleate targets 8 genes: SLC6A2, ADRA1A, HTR2A, HRH1, ADRA1D, DRD2, HTR2C and ADRA1B. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_609', 'drugName': 'Trimipramine Maleate', 'tradeNames_string': 'Surmontil, Trimipramine maleate', 'drugSynonyms_string': 'NSC-758386, Stangyl, Trimipramine maleate', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1979, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newLinked... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.225 | Q17 | What gene does the drug Jnj-18038683 target? | The drug Jnj-18038683 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene HTR7. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_696', 'drugName': 'Jnj-18038683', 'tradeNames_string': '', 'drugSynonyms_string': 'Jnj-18038683', 'linkedDiseasesDrug_string': 'Major Depressive Disorder (MONDO_0002009), Bipolar Disorder (MONDO_0004985)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'newL... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1376 | Q17 | What gene does the drug Proxibarbal target? | The drug Proxibarbal targets 2 genes: MAOA and AOC1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_472', 'drugName': 'Proxibarbal', 'tradeNames_string': '', 'drugSynonyms_string': 'Axeen, Centralgol, HH-184, Hydroxydial, Ipronal, Proxibarbal', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newLinkedTargets_string': 'AOC1 (... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.553 | Q17 | What gene does the drug Drotrecogin Alfa (Activated) target? | The drug Drotrecogin Alfa (Activated) targets 2 genes: F8 and F5. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2502', 'drugName': 'Drotrecogin Alfa (Activated)', 'tradeNames_string': 'Xigris', 'drugSynonyms_string': 'Activated protein c, Drotrecogin alfa, Drotrecogin alfa (activated), Drotrecogin alfa activated, Drotrecogin alfa, activated, Drotrecogin-alfa, LY-203638, LY203638', 'linkedDiseasesDru... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.231 | Q17 | What gene does the drug Hokt3 target? | The drug Hokt3 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene CD3E. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4396', 'drugName': 'Hokt3', 'tradeNames_string': '', 'drugSynonyms_string': 'HOKT3, Hokt3', 'linkedDiseasesDrug_string': 'Psoriatic Arthritis (EFO_0003778), Type 1 Diabetes Mellitus (MONDO_0005147)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False, 'newLinkedT... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.40 | Q17 | What gene does the drug Interferon Alfacon-1 target? | The drug Interferon Alfacon-1 targets 2 genes: IFNAR1 and IFNAR2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4051', 'drugName': 'Interferon Alfacon-1', 'tradeNames_string': 'Infergen', 'drugSynonyms_string': 'Interferon alfacon-1, Rsifn-co', 'linkedDiseasesDrug_string': 'Neoplasm (EFO_0000616), Covid-19 (MONDO_0100096), Chronic Hepatitis C Virus Infection (EFO_0004220), Influenza (EFO_0007328), H... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.548 | Q17 | What gene does the drug Birinapant target? | The drug Birinapant is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 2 genes: BIRC3 and BIRC2 | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_267', 'drugName': 'Birinapant', 'tradeNames_string': '', 'drugSynonyms_string': 'Birinapant, TL-32711, TL32711', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Fallopian Tube Carcinoma (EFO_1000251), Fallopian Tube Cancer (MONDO_0002158), Hepatitis B Virus Infection (EFO_0004197), N... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.245 | Q17 | What gene does the drug Insulin Zinc Susp Purified Beef target? | The drug Insulin Zinc Susp Purified Beef targets the gene INSR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2997', 'drugName': 'Insulin Zinc Susp Purified Beef', 'tradeNames_string': 'Lente iletin ii', 'drugSynonyms_string': 'Insulin zinc susp purified beef', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1980, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newLinkedTargets_string... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.905 | Q17 | What gene does the drug Tenapanor Hydrochloride target? | The drug Tenapanor Hydrochloride targets the gene SLC9A3. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3816', 'drugName': 'Tenapanor Hydrochloride', 'tradeNames_string': 'Ibsrela', 'drugSynonyms_string': 'AZD-1722 HYDROCHLORIDE, AZD1722, AZD1722 hydrochloride, RDX-5791, RDX5791, Tenapanor dihydrochloride, Tenapanor hydrochloride', 'linkedDiseasesDrug_string': 'Irritable Bowel Syndrome (EFO_... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1429 | Q17 | What gene does the drug Phenoxybenzamine Hydrochloride target? | The drug Phenoxybenzamine Hydrochloride targets 6 genes: ADRA2A, ADRA2C, ADRA1A, ADRA1D, ADRA2B and ADRA1B. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1879', 'drugName': 'Phenoxybenzamine Hydrochloride', 'tradeNames_string': 'Dibenyline, Dibenzyline, Phenoxybenzamine hydrochloride', 'drugSynonyms_string': 'Bensylyte hydrochloride, Dibenzylin, Dibenzyline chloride, Dibenzyline hydrochloride, Dibenzyran, NSC-37448, Phenoxybenzamine chlorid... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.139 | Q17 | What gene does the drug Pf-04236921 target? | The drug Pf-04236921 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene IL6. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4784', 'drugName': 'Pf-04236921', 'tradeNames_string': '', 'drugSynonyms_string': 'PF 4236921, PF-04236921, PF-4236921, Pf-04236921', 'linkedDiseasesDrug_string': "Systemic Lupus Erythematosus (MONDO_0007915), Crohn'S Disease (EFO_0000384)", 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1191 | Q17 | What gene does the drug Cilomilast target? | The drug Cilomilast is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 4 genes: PDE4A, PDE4D, PDE4B and PDE4C | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4417', 'drugName': 'Cilomilast', 'tradeNames_string': '', 'drugSynonyms_string': 'Ariflo, Cilomilast, SB 207499, SB-207499', 'linkedDiseasesDrug_string': 'Chronic Obstructive Pulmonary Disease (EFO_0000341)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False, 'n... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1757 | Q17 | What gene does the drug Ibutamoren target? | The drug Ibutamoren is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene GHSR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1333', 'drugName': 'Ibutamoren', 'tradeNames_string': '', 'drugSynonyms_string': 'Ibutamoren, L-163,191, MK-677', 'linkedDiseasesDrug_string': 'Aging (GO_0007568), Fibromyalgia (EFO_0005687)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'newLinkedTargets_... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1573 | Q17 | What gene does the drug Insulin target? | The drug Insulin targets the gene INSR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_495', 'drugName': 'Insulin Glargine', 'tradeNames_string': 'Abasaglar, Abasaglar kwikpen, Basaglar, Ins lantus, Ins lantus opticlik, Ins lantus optiset, Ins lantus solostar, Lantus, Lantus solostar, Toujeo, Toujeo max solostar, Toujeo solostar', 'drugSynonyms_string': 'Basalin, Basalog, Ga... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1443 | Q17 | What gene does the drug Cns-5161 target? | The drug Cns-5161 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 7 genes: GRIN2B, GRIN2A, GRIN3A, GRIN2D, GRIN3B, GRIN1 and GRIN2C | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2181', 'drugName': 'Cns-5161', 'tradeNames_string': '', 'drugSynonyms_string': 'Cns 5161, Cns-5161', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': -1, 'drugIsApproved': False, 'newLinkedTargets_string': 'GRIN1 (ENSG00000176884), GRIN2A (ENSG00000183454... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.836 | Q17 | What gene does the drug Ramipril target? | The drug Ramipril targets the gene ACE. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_6072', 'drugName': 'Ramipril', 'tradeNames_string': 'Altace, Lopace, Ramipril, Ranace, Tritace', 'drugSynonyms_string': 'C09AA05, Cardace, Corpril, Delix, Ecator, HOE 498, HOE-498, Hopace, NSC-758933, Pramace, Ramace, Ramipres, Ramipril, Triatec, Unipril, Vesdil', 'linkedDiseasesDrug_strin... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.451 | Q17 | What gene does the drug Acemetacin target? | The drug Acemetacin targets 2 genes: PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3840', 'drugName': 'Acemetacin', 'tradeNames_string': 'Emflex', 'drugSynonyms_string': 'Acemetacin, NSC-757413, Rantudil', 'linkedDiseasesDrug_string': 'Rheumatic Disease (EFO_0005755)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newLinkedTargets_string'... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.849 | Q17 | What gene does the drug Cosyntropin target? | The drug Cosyntropin targets the gene MC2R. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4137', 'drugName': 'Cosyntropin', 'tradeNames_string': 'Cortrosyn, Cosyntropin, Synacthen, Synacthen depot', 'drugSynonyms_string': 'Corticotropin tetracosapeptide, Cosyntropin, Cosyntropin acetate, Cosyntropin hexaacetate, Tetracosactide, Tetracosactide acetate, Tetracosactide hexaacetate... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1087 | Q17 | What gene does the drug Almotriptan target? | The drug Almotriptan targets 3 genes: HTR1B, HTR1F and HTR1D. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3460', 'drugName': 'Almotriptan Malate', 'tradeNames_string': 'Almotriptan malate, Axert', 'drugSynonyms_string': 'Almogran, Almotriptan d,l-hydrogenmalate, Almotriptan malate, Almotriptan maleate, LAS 31416 D,L-MALATE ACID, LAS-31416, LAS-31416 D,L-MALATE ACID, LAS-31416-D,L-MALATE-ACID, ... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1420 | Q17 | What gene does the drug Etodolac target? | The drug Etodolac targets the gene PTGS2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_916', 'drugName': 'Etodolac', 'tradeNames_string': 'Ebretin, Etodolac, Etolyn, Etopan xl, Lodine, Lodine sr, Lodine xl, Ramodar', 'drugSynonyms_string': '(rs)-etodolic acid, AY-24,236, AY-24-236, AY-24236, Eccoxolac, Edolan, Etodolac, Etodolic acid, Flancox, Lodin xl, NIH-9918, NSC-282126,... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1154 | Q17 | What gene does the drug Sorbinil target? | The drug Sorbinil is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene AKR1B1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2353', 'drugName': 'Sorbinil', 'tradeNames_string': '', 'drugSynonyms_string': 'CP-45,634, CP-45634, NSC-355082, Sorbinil', 'linkedDiseasesDrug_string': 'Diabetic Retinopathy (EFO_0003770)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False, 'newLinkedTargets_st... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1826 | Q17 | What gene does the drug Nitroglycerin target? | The drug Nitroglycerin targets 4 genes: GUCY1A1, GUCY1B2, GUCY1A2 and GUCY1B1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1910', 'drugName': 'Nitroglycerin', 'tradeNames_string': 'Coro-nitro, Deponit 10, Deponit 5, Glytrin, Gonitro, Lenitral 7.5, Minitran, Minitran 10, Minitran 15, Minitran 5, Natirose, Nitriderm tts, Nitro iv, Nitro-bid, Nitro-dur, Nitro-mack ret, Nitrocine, Nitrocontin continus, Nitroglycer... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.588 | Q17 | What gene does the drug Ripasudil target? | The drug Ripasudil is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 2 genes: ROCK2 and ROCK1 | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4729', 'drugName': 'Ripasudil', 'tradeNames_string': '', 'drugSynonyms_string': 'Ripasudil', 'linkedDiseasesDrug_string': "Fuchs Endothelial Corneal Dystrophy (Orphanet_98974), Fuchs' Endothelial Dystrophy (MONDO_0005321), Retinopathy Of Prematurity (EFO_1001158), Glaucoma (MONDO_0005041)"... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1892 | Q17 | What gene does the drug Trospium Chloride target? | The drug Trospium Chloride targets 2 genes: CHRM2 and CHRM3. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4683', 'drugName': 'Trospium Chloride', 'tradeNames_string': 'Flotros, Regurin, Regurin xl, Sanctura, Sanctura xr, Spasmo-lyt, Trospium chloride, Uraplex', 'drugSynonyms_string': 'IP-631, IP631, Relaspium, Spasmex, Spasmolyt, Trospium chloride', 'linkedDiseasesDrug_string': 'Urgency Urinar... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1970 | Q17 | What gene does the drug Hydrocortisone Hemisuccinate target? | The drug Hydrocortisone Hemisuccinate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1752', 'drugName': 'Hydrocortisone Hemisuccinate', 'tradeNames_string': '', 'drugSynonyms_string': 'Hydrocortisone Hemisuccinate, Hydrocortisone succinate, NSC-757049, NSC-7576', 'linkedDiseasesDrug_string': 'Asthma (MONDO_0004979), Leukemia (EFO_0000565), Septic Shock (EFO_0006834), Hemor... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.668 | Q17 | What gene does the drug Bemarituzumab target? | The drug Bemarituzumab is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene FGFR2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1433', 'drugName': 'Bemarituzumab', 'tradeNames_string': '', 'drugSynonyms_string': 'Bemarituzumab, FPA-144', 'linkedDiseasesDrug_string': 'Adenocarcinoma (EFO_0000228), Non-Small Cell Lung Carcinoma (EFO_0003060), Gastric Cancer (MONDO_0001056), Neoplasm (EFO_0000616)', 'yearOfFirstApprov... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.442 | Q17 | What gene does the drug Ivosidenib target? | The drug Ivosidenib targets the gene IDH1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1675', 'drugName': 'Ivosidenib', 'tradeNames_string': 'Tibsovo', 'drugSynonyms_string': 'AG-120, Ivosidenib', 'linkedDiseasesDrug_string': 'Chondrosarcoma (EFO_0000333), Cancer (MONDO_0004992), Neoplasm (EFO_0000616), Liver Disease (EFO_0001421), Pancreatic Ductal Adenocarcinoma (EFO_00025... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1857 | Q17 | What gene does the drug Sacubitril target? | The drug Sacubitril targets the gene MME. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1487', 'drugName': 'Sacubitril', 'tradeNames_string': '', 'drugSynonyms_string': 'AHU-377, AHU377, Sacubitril', 'linkedDiseasesDrug_string': 'Congestive Heart Failure (EFO_0000373), Pulmonary Hypertension (MONDO_0005149), Aortic Valve Insufficiency (EFO_0007148), Peripheral Arterial Diseas... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.382 | Q17 | What gene does the drug Hydroxychloroquine target? | The drug Hydroxychloroquine targets 2 genes: TLR9 and TLR7. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_963', 'drugName': 'Hydroxychloroquine', 'tradeNames_string': '', 'drugSynonyms_string': 'Hydroxychloroquine, Polirreumin', 'linkedDiseasesDrug_string': "Cancer (MONDO_0004992), Multiple Myeloma (EFO_0001378), Rheumatic Disease (EFO_0005755), Chronic Lymphocytic Leukemia (EFO_0000095), Infe... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1478 | Q17 | What gene does the drug Tofogliflozin target? | The drug Tofogliflozin is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene SLC5A2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1052', 'drugName': 'Tofogliflozin', 'tradeNames_string': '', 'drugSynonyms_string': 'CSG 452, CSG-452, CSG452, R-7201, RO-4998452, RO4998452, Tofogliflozin, Tofogliflozin hydrate, Tofogliflozin monohydrate', 'linkedDiseasesDrug_string': 'Type 2 Diabetes Mellitus (MONDO_0005148), Non-Alcoho... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.974 | Q17 | What gene does the drug Febuxostat target? | The drug Febuxostat targets the gene XDH. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1230', 'drugName': 'Febuxostat', 'tradeNames_string': 'Adenuric, Uloric', 'drugSynonyms_string': 'Febuxostat, NSC-758874, TMX-67', 'linkedDiseasesDrug_string': 'Gout (EFO_0004274), Hyperuricemia (EFO_0009104), Angina Pectoris (EFO_0003913), Hypertension (EFO_0000537), Cardiovascular Diseas... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1210 | Q17 | What gene does the drug Insulin Tregopil target? | The drug Insulin Tregopil is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene INSR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_586', 'drugName': 'Insulin Tregopil', 'tradeNames_string': '', 'drugSynonyms_string': 'IN-105, Insulin tregopil', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Type 2 Diabetes Mellitus (MONDO_0005148), Type 1 Diabetes Mellitus (MONDO_0005147)', 'yearOfFirstApproval': 0, 'm... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.318 | Q17 | What gene does the drug Aticaprant target? | The drug Aticaprant is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene OPRK1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_115', 'drugName': 'Aticaprant', 'tradeNames_string': '', 'drugSynonyms_string': 'Aticaprant, CERC-501, Cerc-501, JNJ-67953964-AAA, JSPA-0658, JSPA0658, Jnj-67953964, LY-2456302, LY2456302, Ly2456302', 'linkedDiseasesDrug_string': 'Anxiety (EFO_0005230), Major Depressive Disorder (MONDO_000... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.698 | Q17 | What gene does the drug Axicabtagene Ciloleucel target? | The drug Axicabtagene Ciloleucel targets the gene CD19. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3857', 'drugName': 'Axicabtagene Ciloleucel', 'tradeNames_string': '', 'drugSynonyms_string': 'Axicabtagene ciloleucel, KTE-C19, Yescarta', 'linkedDiseasesDrug_string': 'Follicular Lymphoma (MONDO_0018906), Mantle Cell Lymphoma (EFO_1001469), Neoplasm (EFO_0000616), Neoplasm Of Mature B-Ce... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1505 | Q17 | What gene does the drug Rauwolfia Serpentina target? | The drug Rauwolfia Serpentina targets 6 genes: ADRA2A, ADRA2C, ADRA1A, ADRA1D, ADRA2B and ADRA1B. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4856', 'drugName': 'Rauwolfia Serpentina', 'tradeNames_string': 'Hiwolfia, Hyserpin, Koglucoid, Raudixin, Rauserpin, Rauval, Rauwolfia serpentina, Wolfina', 'drugSynonyms_string': 'Rauvolfia serpentina root, Rauwolfia alkaloids, Rauwolfia alkaloids, whole root, Rauwolfia serpentina, Rauwol... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.430 | Q17 | What gene does the drug Hydroxyprogesterone Caproate target? | The drug Hydroxyprogesterone Caproate targets the gene PGR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4832', 'drugName': 'Hydroxyprogesterone Caproate', 'tradeNames_string': 'Delalutin, Hydroxyprogesterone caproate, Makena, Makena (autoinjector), Makena preservative free, Proluton depot', 'drugSynonyms_string': '17-ohpc, 17.alpha.-caproyloxy-p4, Depo-proluton, Hormofort, Hydroxyprogesteron... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.601 | Q17 | What gene does the drug Fosinopril target? | The drug Fosinopril targets the gene ACE. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2110', 'drugName': 'Fosinopril', 'tradeNames_string': 'Monopril', 'drugSynonyms_string': 'C09AA09, Fosenopril, Fosinopril, SQ-28555', 'linkedDiseasesDrug_string': 'Heart Disease (EFO_0003777), Diabetic Nephropathy (EFO_0000401), Heart Failure (EFO_0003144), Hypertension (EFO_0000537), Card... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1964 | Q17 | What gene does the drug Procyclidine target? | The drug Procyclidine targets the gene CHRM1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5673', 'drugName': 'Procyclidine', 'tradeNames_string': '', 'drugSynonyms_string': 'Elorine, Kemadrine, Lergine, NSC-169103, Procyclidine, Tricoloid, Vagosin', 'linkedDiseasesDrug_string': 'Parkinson Disease (MONDO_0005180)', 'yearOfFirstApproval': 1955, 'maxClinicalTrialPhase': 4, 'drugIs... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.629 | Q17 | What gene does the drug Alfentanil Hydrochloride target? | The drug Alfentanil Hydrochloride targets the gene OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_793', 'drugName': 'Alfentanil Hydrochloride', 'tradeNames_string': 'Alfenta, Alfentanil, Rapifen, Rapifen conc, Rapifen dilute, Rapifen intensive care', 'drugSynonyms_string': 'Alfentanil hydrochloride, Alfentanil hydrochloride cii, Alfentanil hydrochloride monohydrate, R 39,209, R 39209, ... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1170 | Q17 | What gene does the drug Amlodipine target? | The drug Amlodipine targets 4 genes: CACNA1C, CACNA1D, CACNA1S and CACNA1F. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_6132', 'drugName': 'Levamlodipine Maleate', 'tradeNames_string': 'Conjupri', 'drugSynonyms_string': 'Amlodipine maleate, s-, Levamlodipine maleate', 'linkedDiseasesDrug_string': 'Hypertension (EFO_0000537)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, '... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1254 | Q17 | What gene does the drug Vorasidenib target? | The drug Vorasidenib is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 2 genes: IDH1 and IDH2 | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1864', 'drugName': 'Vorasidenib', 'tradeNames_string': '', 'drugSynonyms_string': 'AG-881, Ag-881, Vorasidenib', 'linkedDiseasesDrug_string': 'Astrocytoma (EFO_0000272), Central Nervous System Cancer (EFO_0000326)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': Fa... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.230 | Q17 | What gene does the drug Pilocarpine Hydrochloride target? | The drug Pilocarpine Hydrochloride targets 2 genes: CHRM3 and CHRM1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5678', 'drugName': 'Pilocarpine Hydrochloride', 'tradeNames_string': 'Isopto carpine, Ocusert, Piloc hcl, Pilocarpine hydrochloride, Pilogel, Pilopine, Pilopine hs, Salagen, Sno pilo, Vuity', 'drugSynonyms_string': 'Pilocarpine hcl, Pilocarpine hydrochloride, Pilocarpine monohydrochloride,... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1180 | Q17 | What gene does the drug Eprosartan Mesylate target? | The drug Eprosartan Mesylate targets the gene AGTR1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5528', 'drugName': 'Eprosartan Mesylate', 'tradeNames_string': 'Eprosartan mesylate, Teveten', 'drugSynonyms_string': 'Eprosartan mesilate, Eprosartan mesylate, Eprosartan monomethanesulfonate, SK&F 108566-J, SK&F-108566-J', 'linkedDiseasesDrug_string': 'Hypertension (EFO_0000537), Essenti... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1332 | Q17 | What gene does the drug Methantheline Bromide target? | The drug Methantheline Bromide targets the gene HRH2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3603', 'drugName': 'Methantheline Bromide', 'tradeNames_string': 'Banthine', 'drugSynonyms_string': 'Dixamone bromide, Methantheline bromide, Methanthelinium bromide, NSC-32145, Vagantin', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1951, 'maxClinicalTrialPhase': 4, 'drugIsAppr... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1587 | Q17 | What gene does the drug Flecainide target? | The drug Flecainide targets the gene SCN5A. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5669', 'drugName': 'Flecainide', 'tradeNames_string': '', 'drugSynonyms_string': 'Flecainide, NSC-719273, THN-102 COMPONENT FLECAINIDE', 'linkedDiseasesDrug_string': 'Arrhythmogenic Right Ventricular Dysplasia (Orphanet_247), Pain (EFO_0003843), Cardiac Arrhythmia (EFO_0004269), Ventricula... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.69 | Q17 | What gene does the drug Nizatidine target? | The drug Nizatidine targets the gene HRH2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2673', 'drugName': 'Nizatidine', 'tradeNames_string': 'Axid, Axid ar, Nizatidine, Zinga 150, Zinga 300', 'drugSynonyms_string': 'Acinon, LY 139037, LY-139037, NSC-759289, Nizatidine', 'linkedDiseasesDrug_string': 'Esophagitis (HP_0100633), Duodenal Ulcer (EFO_0004607), Peptic Ulcer (HP_000... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.25 | Q17 | What gene does the drug Solanezumab target? | The drug Solanezumab is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene APP. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3274', 'drugName': 'Solanezumab', 'tradeNames_string': '', 'drugSynonyms_string': 'LY-2062430, LY2062430, Solanezumab', 'linkedDiseasesDrug_string': 'Alzheimer Disease (MONDO_0004975), Cognitive Impairment (HP_0100543)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.147 | Q17 | What gene does the drug Amineptine target? | The drug Amineptine targets 2 genes: DRD1 and DRD2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2419', 'drugName': 'Amineptine', 'tradeNames_string': '', 'drugSynonyms_string': 'Amineptin, Amineptine', 'linkedDiseasesDrug_string': 'Unipolar Depression (EFO_0003761)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newLinkedTargets_string': 'DRD2 (ENSG00... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.542 | Q17 | What gene does the drug Nusinersen Sodium target? | The drug Nusinersen Sodium targets the gene SMN2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_6328', 'drugName': 'Nusinersen Sodium', 'tradeNames_string': 'Spinraza', 'drugSynonyms_string': 'Nusinersen sodium', 'linkedDiseasesDrug_string': 'Spinal Muscular Atrophy (EFO_0008525)', 'yearOfFirstApproval': 2016, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newLinkedTargets_stri... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.818 | Q17 | What gene does the drug Glpg-0259 target? | The drug Glpg-0259 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene MAPKAPK5. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_513', 'drugName': 'Glpg-0259', 'tradeNames_string': '', 'drugSynonyms_string': 'GLPG-0259, GLPG0259, Glpg-0259', 'linkedDiseasesDrug_string': 'Rheumatoid Arthritis (EFO_0000685)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'newLinkedTargets_string': 'MAP... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1120 | Q17 | What gene does the drug Epoetin Zeta target? | The drug Epoetin Zeta targets the gene EPOR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4677', 'drugName': 'Epoetin Zeta', 'tradeNames_string': 'Retacrit', 'drugSynonyms_string': 'Epoetin, Epoetin zeta, Erythropoietin, Erythropoietin for bioassays', 'linkedDiseasesDrug_string': 'Diabetic Foot (EFO_1001459)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApprove... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.88 | Q17 | What gene does the drug Cisapride target? | The drug Cisapride targets the gene HTR4. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3176', 'drugName': 'Cisapride', 'tradeNames_string': 'Alimix, Prepulsid, Prepulsid quicklet, Propulsid, Propulsid quicksolv', 'drugSynonyms_string': 'Cisapride, Cisapride monohydrate, Propulsid, R-51,619, R-51619', 'linkedDiseasesDrug_string': 'Gastrointestinal Disease (EFO_0010282)', 'yea... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
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