uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
values | bio_category stringclasses 14
values |
|---|---|---|---|---|---|---|---|---|
Q17.18 | Q17 | What gene does the drug Ethosuximide target? | The drug Ethosuximide targets 3 genes: CACNA1G, CACNA1I and CACNA1H. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4742', 'drugName': 'Ethosuximide', 'tradeNames_string': 'Emeside, Ethosuximide, Suxinutin, Zarontin', 'drugSynonyms_string': 'CI-366, CN-10,395, CN-10395, Ethosuximide, Ethosuximidum, NSC-64013, PM-671, Pyknolepsinum', 'linkedDiseasesDrug_string': 'Complex Regional Pain Syndrome (EFO_10019... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.130 | Q17 | What gene does the drug Insulin Glulisine target? | The drug Insulin Glulisine targets the gene INSR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5441', 'drugName': 'Insulin Glulisine', 'tradeNames_string': 'Apidra, Apidra solostar, Ins apidra, Ins apidra opticlik, Ins apidra optiset, Ins apidra solostar', 'drugSynonyms_string': 'Glulisine apidra, HMR 1964, HMR-1964, HMR1964, Insulin Glulisine Recombinant, Insulin glulisine, Insulin... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1361 | Q17 | What gene does the drug Cortisone Acetate target? | The drug Cortisone Acetate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1557', 'drugName': 'Cortisone Acetate', 'tradeNames_string': 'Cortate, Cortelan, Cortisone acetate, Cortistab, Cortisyl, Cortone', 'drugSynonyms_string': 'Cortisone, Cortisone 21-acetate, Cortisone Acetate, Cortisone acetate, Cortisone aceticum, NSC-49420', 'linkedDiseasesDrug_string': 'La... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1291 | Q17 | What gene does the drug Tricetamide target? | The drug Tricetamide is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 2 genes: JAK3 and JAK1 | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_970', 'drugName': 'Tricetamide', 'tradeNames_string': '', 'drugSynonyms_string': 'R-548, Tricetamide', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False, 'newLinkedTargets_string': 'JAK1 (ENSG00000162434), JAK3 (ENSG00000105639)'... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1969 | Q17 | What gene does the drug Lithium Carbonate target? | The drug Lithium Carbonate targets 3 genes: GSK3B, GSK3A and IMPA1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3119', 'drugName': 'Lithium Carbonate', 'tradeNames_string': 'Camcolit 250, Camcolit 400, Eskalith, Eskalith cr, Liskonum, Lithane, Lithium carbonate, Lithobid, Lithonate, Lithotabs, Phasal', 'drugSynonyms_string': 'CP-15,467-61, CP-15467-61, CP-1546761, Lithium carbonate, NSC-16895', 'lin... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.935 | Q17 | What gene does the drug Benoxinate Hydrochloride target? | The drug Benoxinate Hydrochloride targets 10 genes: SCN1A, SCN9A, SCN7A, SCN8A, SCN11A, SCN10A, SCN2A, SCN5A, SCN4A and SCN3A. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2819', 'drugName': 'Benoxinate Hydrochloride', 'tradeNames_string': 'Benoxinate hydrochloride', 'drugSynonyms_string': 'Benoxinate hcl, Benoxinate hydrochloride, NSC-759847, Oxibuprocaine chloride, Oxybuprocaine hcl, Oxybuprocaine hydrochloride', 'linkedDiseasesDrug_string': '', 'yearOfFir... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.989 | Q17 | What gene does the drug Betazole Hydrochloride target? | The drug Betazole Hydrochloride targets the gene HRH2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3149', 'drugName': 'Betazole Hydrochloride', 'tradeNames_string': 'Histalog', 'drugSynonyms_string': 'Ametazole, Betazole dihydrochloride, Betazole hcl, Betazole hydrochloride, Betazolium chloride, NSC-759872', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1982, 'maxClinicalTrial... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1965 | Q17 | What gene does the drug Alclometasone Dipropionate target? | The drug Alclometasone Dipropionate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2070', 'drugName': 'Alclometasone Dipropionate', 'tradeNames_string': 'Aclovate, Alclometasone dipropionate, Modrasone', 'drugSynonyms_string': 'Alclometasone, Alclometasone 17,21-dipropionate, Alclometasone dipropionate, NSC-758914, SCH 22219, SCH-22219', 'linkedDiseasesDrug_string': 'Non... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.193 | Q17 | What gene does the drug Isoxicam target? | The drug Isoxicam targets 2 genes: PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1802', 'drugName': 'Isoxicam', 'tradeNames_string': 'Maxicam', 'drugSynonyms_string': 'Isoxicam, NSC-758436, W 8495, W-8495', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), ... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1149 | Q17 | What gene does the drug Pentolinium Tartrate target? | The drug Pentolinium Tartrate targets 2 genes: CHRNB4 and CHRNA3. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4468', 'drugName': 'Pentolinium Tartrate', 'tradeNames_string': 'Ansolysen', 'drugSynonyms_string': 'NSC-759890, Pentolinium tartrate, Pentolonium tartrate, Pentolonum bitartrate', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': T... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1001 | Q17 | What gene does the drug Bepotastine target? | The drug Bepotastine targets the gene HRH1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3215', 'drugName': 'Bepotastine Besylate', 'tradeNames_string': 'Bepreve', 'drugSynonyms_string': 'BB, Bepotastine Besilate, Bepotastine benzenesulfonate salt, Bepotastine besilate, Bepotastine besylate, TAU-284, Talion', 'linkedDiseasesDrug_string': 'Allergic Conjunctivitis (EFO_0007141),... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1956 | Q17 | What gene does the drug Veralipride target? | The drug Veralipride targets the gene DRD2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_775', 'drugName': 'Veralipride', 'tradeNames_string': 'Agreal', 'drugSynonyms_string': 'Agradil, Veralipride', 'linkedDiseasesDrug_string': 'Psychosis (EFO_0005407)', 'yearOfFirstApproval': 1979, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newLinkedTargets_string': 'DRD2 (ENSG0000... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1657 | Q17 | What gene does the drug Ivabradine target? | The drug Ivabradine targets the gene HCN4. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_32', 'drugName': 'Ivabradine', 'tradeNames_string': 'Corlanor, Procoralan', 'drugSynonyms_string': 'Ivabradine, S-16257', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Orthostatic Hypotension (EFO_0005252), Coronary Artery Disease (EFO_0001645), Non-St Elevation Myocardial Infarcti... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.613 | Q17 | What gene does the drug Dexamethasone Acetate target? | The drug Dexamethasone Acetate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4777', 'drugName': 'Dexamethasone Acetate', 'tradeNames_string': 'Decadron, Decadron-la, Dexamethasone acetate', 'drugSynonyms_string': 'Dectancyl, Dexamethasone 21-acetate, Dexamethasone acetate, Dexamethasone acetate anhydrous, Dexamethasone acetate monohydrate, Dexamethasoni acetas, Dex... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.183 | Q17 | What gene does the drug Brilanestrant target? | The drug Brilanestrant is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene ESR1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4957', 'drugName': 'Brilanestrant', 'tradeNames_string': '', 'drugSynonyms_string': 'ARN-810, Brilanestrant, GDC-0810, Gdc-0810, RG-6046, RG6046', 'linkedDiseasesDrug_string': 'Breast Cancer (MONDO_0007254)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'n... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.305 | Q17 | What gene does the drug Fluphenazine Enanthate target? | The drug Fluphenazine Enanthate targets the gene DRD2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_905', 'drugName': 'Fluphenazine Enanthate', 'tradeNames_string': 'Moditen enant, Prolixin, Prolixin enanthate', 'drugSynonyms_string': 'Flufenan, Fluphenazine, Fluphenazine enantate, Fluphenazine enanthate, Fluphenazine maleate, Fluphenazini enantas, SQ 16,114, SQ 16144', 'linkedDiseasesDr... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.502 | Q17 | What gene does the drug Mifamurtide target? | The drug Mifamurtide targets the gene NOD2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1449', 'drugName': 'Mifamurtide', 'tradeNames_string': '', 'drugSynonyms_string': 'CGP-19835, L-MTP-PE, Mifamurtide, Mifamurtide sodium hydrate, Mifamurtide sodium salt monohydrate, Sodium mifamurtide', 'linkedDiseasesDrug_string': 'Osteosarcoma (EFO_0000637), Neoplasm (EFO_0000616)', 'yea... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1696 | Q17 | What gene does the drug Doxazosin Mesylate target? | The drug Doxazosin Mesylate targets 3 genes: ADRA1D, ADRA1B and ADRA1A. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_924', 'drugName': 'Doxazosin Mesylate', 'tradeNames_string': 'Cardozin xl, Cardura, Cardura xl, Cascor, Colixil xl, Doxadura, Doxazosin mesylate, Doxzogen xl, Larbex xl, Oxandosin xl, Raporsin xl, Slocinx xl', 'drugSynonyms_string': 'Alfadil, Doxazosin (as mesilate), Doxazosin mesilate, Do... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1721 | Q17 | What gene does the drug Enrasentan target? | The drug Enrasentan is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 2 genes: EDNRA and EDNRB | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3107', 'drugName': 'Enrasentan', 'tradeNames_string': '', 'drugSynonyms_string': 'Enrasentan, SB-217242, Sb-217242', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'newLinkedTargets_string': 'EDNRB (ENSG00000136160), EDNRA (E... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1662 | Q17 | What gene does the drug Prednisolone Sodium Phosphate target? | The drug Prednisolone Sodium Phosphate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2586', 'drugName': 'Prednisolone Sodium Phosphate', 'tradeNames_string': 'Codelsol, Cortisate, Hydeltrasol, Inflamase, Inflamase forte, Inflamase mild, Metreton, Orapred, Orapred odt, Pediapred, Predair, Predair forte, Prednisolone sodium phosphate, Predsol, Predsol-n', 'drugSynonyms_strin... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1639 | Q17 | What gene does the drug Coltuximab Ravtansine target? | The drug Coltuximab Ravtansine is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene CD19. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_555', 'drugName': 'Coltuximab Ravtansine', 'tradeNames_string': '', 'drugSynonyms_string': 'Coltuximab ravtansine, SAR-3419, SAR3419', 'linkedDiseasesDrug_string': 'Diffuse Large B-Cell Lymphoma (EFO_0000403), Non-Hodgkins Lymphoma (EFO_0005952), Acute Lymphoblastic Leukemia (EFO_0000220)'... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.523 | Q17 | What gene does the drug Linsitinib target? | The drug Linsitinib is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 2 genes: IGF1R and INSR | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4973', 'drugName': 'Linsitinib', 'tradeNames_string': '', 'drugSynonyms_string': 'ASP-7487, Linsitinib, OSI-906, OSI-906AA', 'linkedDiseasesDrug_string': 'Hepatocellular Carcinoma (EFO_0000182), Head And Neck Malignant Neoplasia (EFO_0006859), Ewing Sarcoma (EFO_0000174), Small Cell Lung C... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1985 | Q17 | What gene does the drug Tremelimumab target? | The drug Tremelimumab targets the gene CTLA4. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_680', 'drugName': 'Tremelimumab', 'tradeNames_string': 'Imjudo', 'drugSynonyms_string': 'CP-675,206, CP-675206, PF-06753388, TICILIMUMAB, Ticilimumab, Tremelimumab, Tremelimumab (genetical recombination), Tremelimumab-actl', 'linkedDiseasesDrug_string': 'Ovarian Carcinoma (EFO_0001075), Ca... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1078 | Q17 | What gene does the drug Cetrorelix Acetate target? | The drug Cetrorelix Acetate targets the gene GNRHR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3467', 'drugName': 'Cetrorelix Acetate', 'tradeNames_string': 'Cetrotide', 'drugSynonyms_string': 'Cetrorelix, Cetrorelix acetate, Cetrotide acetate, D-20761, NS-75A, SB-075 ACETATE', 'linkedDiseasesDrug_string': 'Polycystic Ovary Syndrome (EFO_0000660), Infertility (EFO_0000545)', 'yearOf... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.482 | Q17 | What gene does the drug Meclofenamate Sodium target? | The drug Meclofenamate Sodium targets 3 genes: PTGS2, PTGS1 and ALOX5. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3724', 'drugName': 'Meclofenamate Sodium', 'tradeNames_string': 'Meclodium, Meclofenamate sodium, Meclomen', 'drugSynonyms_string': 'CL-583.NA SALT, Meclofenamate sodium, Meclofenamate sodium anhydrous, Meclofenamate sodium hydrate, Meclofenamic acid sodium, NSC-757088, Sodium meclofenamat... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.160 | Q17 | What gene does the drug Tesidolumab target? | The drug Tesidolumab is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene C5. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1037', 'drugName': 'Tesidolumab', 'tradeNames_string': '', 'drugSynonyms_string': 'LFG-316, LFG316, Lfg316, NOV-4, Tesidolumab', 'linkedDiseasesDrug_string': 'Age-Related Macular Degeneration (EFO_0001365), Intermediate Uveitis (EFO_1000986), Wet Macular Degeneration (EFO_0004683)', 'yearO... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1253 | Q17 | What gene does the drug Mitotane target? | The drug Mitotane targets 2 genes: CYP11B1 and CYP11A1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5754', 'drugName': 'Mitotane', 'tradeNames_string': 'Lysodren, Opddd', 'drugSynonyms_string': "CB 313, CB-313, Chloditan, Chlodithane, Mitotan, Mitotane, NSC-38721, O,p'-ddd, O,p'-ddd,o p'-tde, O,p'-tde, Opeprim", 'linkedDiseasesDrug_string': 'Carcinoma (EFO_0000313), Prostate Cancer (MOND... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1205 | Q17 | What gene does the drug Ranitidine Bismuth Citrate target? | The drug Ranitidine Bismuth Citrate targets the gene HRH2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4141', 'drugName': 'Ranitidine Bismuth Citrate', 'tradeNames_string': 'Pylorid, Tritec', 'drugSynonyms_string': 'GR 122311X, GR-122311X, Ranitidine bismuth citrate, Ranitidine bismutrex', 'linkedDiseasesDrug_string': 'Peptic Ulcer (HP_0004398), Helicobacter Pylori Infectious Disease (EFO_1... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.17 | Q17 | What gene does the drug Rituximab target? | The drug Rituximab targets the gene MS4A1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4195', 'drugName': 'Rituximab', 'tradeNames_string': 'Mabthera, Mabthera rituxan, Rituxan', 'drugSynonyms_string': 'ABP-798, ABP798, BI695500, Bi 695500, Bi-695500, Blitzima, CT-P10, Gp2013, HS-006, HS-006 (RITUXIMAB BIOSIMILAR), HS006, IDEC-102, IDEC-C2B8, Mk-8808, Pf-05280586, R-105 IDEC... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1550 | Q17 | What gene does the drug Levonorgestrel target? | The drug Levonorgestrel targets the gene PGR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2857', 'drugName': 'Levonorgestrel', 'tradeNames_string': 'Athentia next, Emerres, Emerres una, Ezinelle, Fallback solo, Her style, Isteranda, Jadelle, Jaydess, Kyleena, Levonelle, Levonelle one step, Levonelle-2, Levonorgestrel, Levosert, Liletta, Microval, Mirena, Norgeston, Norplant, No... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1081 | Q17 | What gene does the drug Perhexiline target? | The drug Perhexiline targets 3 genes: CPT2, CPT1B and MTOR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1726', 'drugName': 'Perhexiline Maleate', 'tradeNames_string': 'Pexid, Pexsig', 'drugSynonyms_string': 'NSC-758409, Perhexiline maleate, Perhexilinum', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1974, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newLinkedTargets_string... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1972 | Q17 | What gene does the drug Trihexyphenidyl target? | The drug Trihexyphenidyl targets the gene CHRM1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_6217', 'drugName': 'Trihexyphenidyl', 'tradeNames_string': '', 'drugSynonyms_string': 'Apo-trihex, NSC-12268, Trihexyphenidyl', 'linkedDiseasesDrug_string': 'Dystonic Disorder (MONDO_0003441), Parkinson Disease (MONDO_0005180)', 'yearOfFirstApproval': 1949, 'maxClinicalTrialPhase': 4, 'dru... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.552 | Q17 | What gene does the drug Codeine Polistirex target? | The drug Codeine Polistirex targets 3 genes: OPRK1, OPRM1 and OPRD1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_494', 'drugName': 'Codeine Polistirex', 'tradeNames_string': '', 'drugSynonyms_string': 'Codeine polistirex', 'linkedDiseasesDrug_string': 'Cough (HP_0012735)', 'yearOfFirstApproval': 1985, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newLinkedTargets_string': 'OPRK1 (ENSG000000825... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1554 | Q17 | What gene does the drug Methamphetamine Hydrochloride target? | The drug Methamphetamine Hydrochloride targets 3 genes: SLC6A4, SLC6A2 and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5557', 'drugName': 'Methamphetamine Hydrochloride', 'tradeNames_string': 'Desoxyn, Methampex, Methamphetamine hydrochloride', 'drugSynonyms_string': 'Desoxyephedrine hydrochloride, Metamfetamine hydrochloride, Methamphetamine hcl, Methamphetamine hydrochloride, Methamphetamine hydrochlorid... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.665 | Q17 | What gene does the drug Hexylcaine target? | The drug Hexylcaine targets 10 genes: SCN1A, SCN9A, SCN7A, SCN8A, SCN11A, SCN10A, SCN2A, SCN5A, SCN4A and SCN3A. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_702', 'drugName': 'Hexylcaine Hydrochloride', 'tradeNames_string': 'Cyclaine', 'drugSynonyms_string': 'Hexylcaine HCl, Hexylcaine hcl, Hexylcaine hydrochloride', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newLinkedTarg... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1626 | Q17 | What gene does the drug Azd9056 target? | The drug Azd9056 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene P2RX7. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4477', 'drugName': 'Azd9056', 'tradeNames_string': '', 'drugSynonyms_string': 'AZD9056, Azd 9056, Azd-9056, Azd9056', 'linkedDiseasesDrug_string': 'Rheumatoid Arthritis (EFO_0000685)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'newLinkedTargets_string':... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1028 | Q17 | What gene does the drug Mavacamten target? | The drug Mavacamten targets 7 genes: MYL7, MYH6, MYL3, MYL4, MYL2, MYH7B and MYH7. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1036', 'drugName': 'Mavacamten', 'tradeNames_string': 'Camzyos', 'drugSynonyms_string': 'Camzyos, MYK-461, Mavacamten, Myk-461, SAR-439152', 'linkedDiseasesDrug_string': 'Heart Failure (EFO_0003144), Hypertrophic Cardiomyopathy (EFO_0000538)', 'yearOfFirstApproval': 2022, 'maxClinicalTrial... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1994 | Q17 | What gene does the drug Varlilumab target? | The drug Varlilumab is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene CD27. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2539', 'drugName': 'Varlilumab', 'tradeNames_string': '', 'drugSynonyms_string': 'CDX-1127, Varlilumab', 'linkedDiseasesDrug_string': 'Astrocytoma (EFO_0000272), Urogenital Neoplasm (EFO_0003863), Oligoastrocytoma (EFO_0000630), Non-Small Cell Lung Carcinoma (EFO_0003060), Gallbladder Carc... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1519 | Q17 | What gene does the drug Concizumab target? | The drug Concizumab is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene TFPI. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2877', 'drugName': 'Concizumab', 'tradeNames_string': '', 'drugSynonyms_string': 'Anti-TFPI, Concizumab, MAB-2021, NN-7415, NN7415, NNC 0172-0000-2021, NNC-0172-0000-2021, mAb2021', 'linkedDiseasesDrug_string': 'Hemophilia B (MONDO_0010604), Hemophilia A (MONDO_0010602)', 'yearOfFirstAppro... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.968 | Q17 | What gene does the drug Mecasermin target? | The drug Mecasermin targets the gene IGF1R. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_672', 'drugName': 'Mecasermin Rinfabate', 'tradeNames_string': 'Iplex, Somatokine', 'drugSynonyms_string': 'Mecasermin Rinfabate Recombinant, Mecasermin rinfabate, Mecasermin rinfabate recombinant, RHIGF-I/RHIGFBP-3', 'linkedDiseasesDrug_string': 'Myotonic Dystrophy (MONDO_0016107), Steine... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1883 | Q17 | What gene does the drug Everolimus target? | The drug Everolimus targets the gene FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1925', 'drugName': 'Everolimus', 'tradeNames_string': 'Afinitor, Afinitor disperz, Certican, Votubia, Zortress', 'drugSynonyms_string': '40-o-(2-hydroxyethyl)-rapamycin, Everolimus, RAD 666, RAD-001, RAD-666, RAD001, SDZ-RAD, Sdz rad', 'linkedDiseasesDrug_string': "Multiple Myeloma (EFO_00... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.287 | Q17 | What gene does the drug Dapagliflozin target? | The drug Dapagliflozin targets the gene SLC5A2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1158', 'drugName': 'Dapagliflozin', 'tradeNames_string': 'Forxiga', 'drugSynonyms_string': 'BMS-512148, BMS-512148-05, Dapagliflozin, LYN-045', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Alzheimer Disease (MONDO_0004975), Coronary Artery Disease (EFO_0001645), Covid-19 ... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q19.27 | Q19 | Which SNP is most significantly associated with ALS in the Cerebellar Hemisphere? | There are no significantly associated SNPs with ALS in the Cerebellar Hemisphere. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND LOWER(Omic_tissue) = 'cerebellar hemisphere' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.113 | Q19 | Which SNP is most significantly associated with PSP in the Cerebellar Hemisphere? | There are no significantly associated SNPs with PSP in the Cerebellar Hemisphere. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND LOWER(Omic_tissue) = 'cerebellar hemisphere' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.83 | Q19 | Which SNP is most significantly associated with LBD in the Spinalcord? | There are no significantly associated SNPs with LBD in the Spinalcord. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND LOWER(Omic_tissue) = 'spinalcord' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.57 | Q19 | Which SNP is most significantly associated with FTD in the Nucleus Accumbens Basal? | There are no significantly associated SNPs with FTD in the Nucleus Accumbens Basal. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND LOWER(Omic_tissue) = 'nucleus accumbens basal' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.45 | Q19 | Which SNP is most significantly associated with FTD in the Amygdala? | There are no significantly associated SNPs with FTD in the Amygdala. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND LOWER(Omic_tissue) = 'amygdala' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.98 | Q19 | Which SNP is most significantly associated with PD in the Liver? | The most significantly associated SNP with PD in the Liver is rs55974014, located in the DND1P1 gene, with an adjusted SMR multi-SNP P-value of 1.42e-12 and a HEIDI value of 6.9873e-01. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND LOWER(Omic_tissue) = 'liver' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1476423', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Omic_tissue': 'Liver', 'p_SMR_multi': 1.423253e-12, 'p_HEIDI': 0.6987305, 'A1': 'A', 'A2': 'C', 'Freq': 0.226994, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.82 | Q19 | Which SNP is most significantly associated with LBD in the Skeletal Muscle? | There are no significantly associated SNPs with LBD in the Skeletal Muscle. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND LOWER(Omic_tissue) = 'skeletal muscle' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.127 | Q19 | Which SNP is most significantly associated with PSP in the Whole Blood? | The most significantly associated SNP with PSP in the Whole Blood is rs11012, located in the ARHGAP27 gene, with an adjusted SMR multi-SNP P-value of 1.36e-13 and a HEIDI value of 7.9699e-02. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND LOWER(Omic_tissue) = 'whole blood' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041707', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Omic_tissue': 'Whole Blood', 'p_SMR_multi': 1.359097e-13, 'p_HEIDI': 0.07969932, 'A1': 'T', 'A2': 'C', 'Freq': 0.191207, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.116 | Q19 | Which SNP is most significantly associated with PSP in the Frontal Cortex? | There are no significantly associated SNPs with PSP in the Frontal Cortex. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND LOWER(Omic_tissue) = 'frontal cortex' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.64 | Q19 | Which SNP is most significantly associated with FTD in the Whole Blood? | There are no significantly associated SNPs with FTD in the Whole Blood. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND LOWER(Omic_tissue) = 'whole blood' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.46 | Q19 | Which SNP is most significantly associated with FTD in the Anterior Cingulate Cortex BA24? | There are no significantly associated SNPs with FTD in the Anterior Cingulate Cortex BA24. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND LOWER(Omic_tissue) = 'anterior cingulate cortex ba24' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT... | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.5 | Q19 | Which SNP is most significantly associated with AD in the Cerebellar Hemisphere? | The most significantly associated SNP with AD in the Cerebellar Hemisphere is rs1623264, located in the PVRIG gene, with an adjusted SMR multi-SNP P-value of 1.92e-07 and a HEIDI value of 2.0119e-01. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND LOWER(Omic_tissue) = 'cerebellar hemisphere' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1172874', 'topRSID': 'rs1623264', 'Disease': 'AD', 'Omic_tissue': 'Cerebellar Hemisphere', 'p_SMR_multi': 1.917735e-07, 'p_HEIDI': 0.2011887, 'A1': 'C', 'A2': 'G', 'Freq': 0.736196, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.19 | Q19 | Which SNP is most significantly associated with AD in the Substantia nigra? | The most significantly associated SNP with AD in the Substantia nigra is rs1987580, located in the STAG3 gene, with an adjusted SMR multi-SNP P-value of 5.98e-07 and a HEIDI value of 1.3896e-02. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND LOWER(Omic_tissue) = 'substantia nigra' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1446227', 'topRSID': 'rs1987580', 'Disease': 'AD', 'Omic_tissue': 'Substantia nigra', 'p_SMR_multi': 5.982321e-07, 'p_HEIDI': 0.01389594, 'A1': 'C', 'A2': 'A', 'Freq': 0.295501, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.97 | Q19 | Which SNP is most significantly associated with PD in the Hypothalamus? | The most significantly associated SNP with PD in the Hypothalamus is rs55974014, located in the RP11-259G18.3 gene, with an adjusted SMR multi-SNP P-value of 1.15e-11 and a HEIDI value of 3.4628e-01. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND LOWER(Omic_tissue) = 'hypothalamus' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1462897', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Omic_tissue': 'Hypothalamus', 'p_SMR_multi': 1.146115e-11, 'p_HEIDI': 0.346278, 'A1': 'A', 'A2': 'C', 'Freq': 0.226994, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.37 | Q19 | Which SNP is most significantly associated with ALS in the Prefrontal Cortex? | There are no significantly associated SNPs with ALS in the Prefrontal Cortex. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND LOWER(Omic_tissue) = 'prefrontal cortex' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.96 | Q19 | Which SNP is most significantly associated with PD in the Hippocampus? | The most significantly associated SNP with PD in the Hippocampus is rs56040418, located in the CRHR1-IT1 gene, with an adjusted SMR multi-SNP P-value of 9.21e-12 and a HEIDI value of 9.2065e-01. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND LOWER(Omic_tissue) = 'hippocampus' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1386990', 'topRSID': 'rs56040418', 'Disease': 'PD', 'Omic_tissue': 'Hippocampus', 'p_SMR_multi': 9.214326e-12, 'p_HEIDI': 0.9206501, 'A1': 'T', 'A2': 'C', 'Freq': 0.236196, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.20 | Q19 | Which SNP is most significantly associated with AD in the Tibial Nerve? | The most significantly associated SNP with AD in the Tibial Nerve is rs11769559, located in the EPHA1-AS1 gene, with an adjusted SMR multi-SNP P-value of 1.34e-09 and a HEIDI value of 5.0508e-02. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND LOWER(Omic_tissue) = 'tibial nerve' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1287997', 'topRSID': 'rs11769559', 'Disease': 'AD', 'Omic_tissue': 'Tibial Nerve', 'p_SMR_multi': 1.341267e-09, 'p_HEIDI': 0.05050774, 'A1': 'C', 'A2': 'T', 'Freq': 0.43047, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.122 | Q19 | Which SNP is most significantly associated with PSP in the Putamen Basal Ganglia? | The most significantly associated SNP with PSP in the Putamen Basal Ganglia is rs17692129, located in the NSFP1 gene, with an adjusted SMR multi-SNP P-value of 1.45e-11 and a HEIDI value of 3.9510e-01. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND LOWER(Omic_tissue) = 'putamen basal ganglia' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1596828', 'topRSID': 'rs17692129', 'Disease': 'PSP', 'Omic_tissue': 'Putamen Basal Ganglia', 'p_SMR_multi': 1.446027e-11, 'p_HEIDI': 0.3950962, 'A1': 'T', 'A2': 'C', 'Freq': 0.340491, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.11 | Q19 | Which SNP is most significantly associated with AD in the Hypothalamus? | The most significantly associated SNP with AD in the Hypothalamus is rs866500, located in the STAG3 gene, with an adjusted SMR multi-SNP P-value of 6.66e-07 and a HEIDI value of 4.9138e-01. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND LOWER(Omic_tissue) = 'hypothalamus' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1453489', 'topRSID': 'rs866500', 'Disease': 'AD', 'Omic_tissue': 'Hypothalamus', 'p_SMR_multi': 6.65674e-07, 'p_HEIDI': 0.4913814, 'A1': 'G', 'A2': 'A', 'Freq': 0.766871, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.41 | Q19 | Which SNP is most significantly associated with ALS in the Substantia nigra? | There are no significantly associated SNPs with ALS in the Substantia nigra. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND LOWER(Omic_tissue) = 'substantia nigra' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.12 | Q19 | Which SNP is most significantly associated with AD in the Liver? | The most significantly associated SNP with AD in the Liver is rs73045691, located in the APOC4 gene, with an adjusted SMR multi-SNP P-value of 3.17e-11 and a HEIDI value of 4.6883e-01. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND LOWER(Omic_tissue) = 'liver' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1466879', 'topRSID': 'rs73045691', 'Disease': 'AD', 'Omic_tissue': 'Liver', 'p_SMR_multi': 3.171686e-11, 'p_HEIDI': 0.4688313, 'A1': 'A', 'A2': 'G', 'Freq': 0.326176, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.100 | Q19 | Which SNP is most significantly associated with PD in the Nucleus Accumbens Basal? | The most significantly associated SNP with PD in the Nucleus Accumbens Basal is rs55974014, located in the KANSL1-AS1 gene, with an adjusted SMR multi-SNP P-value of 1.08e-12 and a HEIDI value of 7.2357e-02. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND LOWER(Omic_tissue) = 'nucleus accumbens basal' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1730065', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Omic_tissue': 'Nucleus Accumbens Basal', 'p_SMR_multi': 1.078886e-12, 'p_HEIDI': 0.07235706, 'A1': 'A', 'A2': 'C', 'Freq': 0.226994, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.106 | Q19 | Which SNP is most significantly associated with PD in the Tibial Nerve? | The most significantly associated SNP with PD in the Tibial Nerve is rs9936329, located in the KAT8 gene, with an adjusted SMR multi-SNP P-value of 3.76e-08 and a HEIDI value of 6.9711e-02. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND LOWER(Omic_tissue) = 'tibial nerve' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1328410', 'topRSID': 'rs9936329', 'Disease': 'PD', 'Omic_tissue': 'Tibial Nerve', 'p_SMR_multi': 3.760457e-08, 'p_HEIDI': 0.06971106, 'A1': 'T', 'A2': 'G', 'Freq': 0.380368, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.79 | Q19 | Which SNP is most significantly associated with LBD in the Nucleus Accumbens Basal? | There are no significantly associated SNPs with LBD in the Nucleus Accumbens Basal. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND LOWER(Omic_tissue) = 'nucleus accumbens basal' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.1 | Q19 | Which SNP is most significantly associated with AD in the Amygdala? | The most significantly associated SNP with AD in the Amygdala is rs2950520, located in the PVRIG gene, with an adjusted SMR multi-SNP P-value of 2.60e-07 and a HEIDI value of 1.6252e-01. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND LOWER(Omic_tissue) = 'amygdala' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1597706', 'topRSID': 'rs2950520', 'Disease': 'AD', 'Omic_tissue': 'Amygdala', 'p_SMR_multi': 2.603229e-07, 'p_HEIDI': 0.1625242, 'A1': 'C', 'A2': 'T', 'Freq': 0.737219, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.80 | Q19 | Which SNP is most significantly associated with LBD in the Prefrontal Cortex? | The most significantly associated SNP with LBD in the Prefrontal Cortex is rs3806789, located in the RP11-67M1.1 gene, with an adjusted SMR multi-SNP P-value of 1.43e-06 and a HEIDI value of 1.2764e-01. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND LOWER(Omic_tissue) = 'prefrontal cortex' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1226644', 'topRSID': 'rs3806789', 'Disease': 'LBD', 'Omic_tissue': 'Prefrontal Cortex', 'p_SMR_multi': 1.43087e-06, 'p_HEIDI': 0.1276414, 'A1': 'T', 'A2': 'C', 'Freq': 0.489775, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.70 | Q19 | Which SNP is most significantly associated with LBD in the Cerebellar Hemisphere? | There are no significantly associated SNPs with LBD in the Cerebellar Hemisphere. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND LOWER(Omic_tissue) = 'cerebellar hemisphere' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.71 | Q19 | Which SNP is most significantly associated with LBD in the Cerebellum? | There are no significantly associated SNPs with LBD in the Cerebellum. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND LOWER(Omic_tissue) = 'cerebellum' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.13 | Q19 | Which SNP is most significantly associated with AD in the Multi Ancestry Whole Brain? | The most significantly associated SNP with AD in the Multi Ancestry Whole Brain is rs2897358, located in the PILRB gene, with an adjusted SMR multi-SNP P-value of 1.21e-09 and a HEIDI value of 6.5833e-02. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND LOWER(Omic_tissue) = 'multi ancestry whole brain' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1392628', 'topRSID': 'rs2897358', 'Disease': 'AD', 'Omic_tissue': 'Multi Ancestry Whole Brain', 'p_SMR_multi': 1.205748e-09, 'p_HEIDI': 0.06583308, 'A1': 'G', 'A2': 'C', 'Freq': 0.200409, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.43 | Q19 | Which SNP is most significantly associated with ALS in the Whole Blood? | The most significantly associated SNP with ALS in the Whole Blood is rs9969832, located in the C9orf72 gene, with an adjusted SMR multi-SNP P-value of 6.71e-11 and a HEIDI value of 6.8091e-01. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND LOWER(Omic_tissue) = 'whole blood' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_745098', 'topRSID': 'rs9969832', 'Disease': 'ALS', 'Omic_tissue': 'Whole Blood', 'p_SMR_multi': 6.714586e-11, 'p_HEIDI': 0.6809056, 'A1': 'T', 'A2': 'C', 'Freq': 0.233129, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.32 | Q19 | Which SNP is most significantly associated with ALS in the Hippocampus? | There are no significantly associated SNPs with ALS in the Hippocampus. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND LOWER(Omic_tissue) = 'hippocampus' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.28 | Q19 | Which SNP is most significantly associated with ALS in the Cerebellum? | There are no significantly associated SNPs with ALS in the Cerebellum. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND LOWER(Omic_tissue) = 'cerebellum' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.25 | Q19 | Which SNP is most significantly associated with ALS in the Basal Ganglia? | There are no significantly associated SNPs with ALS in the Basal Ganglia. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND LOWER(Omic_tissue) = 'basal ganglia' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.95 | Q19 | Which SNP is most significantly associated with PD in the Frontal Cortex? | The most significantly associated SNP with PD in the Frontal Cortex is rs62057151, located in the LRRC37A4P gene, with an adjusted SMR multi-SNP P-value of 2.03e-12 and a HEIDI value of 7.4811e-01. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND LOWER(Omic_tissue) = 'frontal cortex' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1168831', 'topRSID': 'rs62057151', 'Disease': 'PD', 'Omic_tissue': 'Frontal Cortex', 'p_SMR_multi': 2.026026e-12, 'p_HEIDI': 0.7481131, 'A1': 'T', 'A2': 'C', 'Freq': 0.241309, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.112 | Q19 | Which SNP is most significantly associated with PSP in the Caudate Basal Ganglia? | There are no significantly associated SNPs with PSP in the Caudate Basal Ganglia. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND LOWER(Omic_tissue) = 'caudate basal ganglia' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.93 | Q19 | Which SNP is most significantly associated with PD in the Cerebellum? | The most significantly associated SNP with PD in the Cerebellum is rs1991556, located in the LRRC37A4P gene, with an adjusted SMR multi-SNP P-value of 5.01e-13 and a HEIDI value of 3.5028e-02. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND LOWER(Omic_tissue) = 'cerebellum' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1710342', 'topRSID': 'rs1991556', 'Disease': 'PD', 'Omic_tissue': 'Cerebellum', 'p_SMR_multi': 5.010673e-13, 'p_HEIDI': 0.0350284, 'A1': 'A', 'A2': 'G', 'Freq': 0.238241, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.16 | Q19 | Which SNP is most significantly associated with AD in the Putamen Basal Ganglia? | The most significantly associated SNP with AD in the Putamen Basal Ganglia is rs1623264, located in the PVRIG gene, with an adjusted SMR multi-SNP P-value of 2.79e-07 and a HEIDI value of 8.5606e-02. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND LOWER(Omic_tissue) = 'putamen basal ganglia' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1583222', 'topRSID': 'rs1623264', 'Disease': 'AD', 'Omic_tissue': 'Putamen Basal Ganglia', 'p_SMR_multi': 2.788121e-07, 'p_HEIDI': 0.08560628, 'A1': 'C', 'A2': 'G', 'Freq': 0.736196, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.78 | Q19 | Which SNP is most significantly associated with LBD in the Multi Ancestry Whole Brain? | There are no significantly associated SNPs with LBD in the Multi Ancestry Whole Brain. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND LOWER(Omic_tissue) = 'multi ancestry whole brain' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.23 | Q19 | Which SNP is most significantly associated with ALS in the Amygdala? | There are no significantly associated SNPs with ALS in the Amygdala. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND LOWER(Omic_tissue) = 'amygdala' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.48 | Q19 | Which SNP is most significantly associated with FTD in the Caudate Basal Ganglia? | There are no significantly associated SNPs with FTD in the Caudate Basal Ganglia. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND LOWER(Omic_tissue) = 'caudate basal ganglia' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.66 | Q19 | Which SNP is most significantly associated with LBD in the Amygdala? | There are no significantly associated SNPs with LBD in the Amygdala. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND LOWER(Omic_tissue) = 'amygdala' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.107 | Q19 | Which SNP is most significantly associated with PD in the Whole Blood? | The most significantly associated SNP with PD in the Whole Blood is rs55974014, located in the RP11-707O23.5 gene, with an adjusted SMR multi-SNP P-value of 2.14e-15 and a HEIDI value of 1.0447e-01. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND LOWER(Omic_tissue) = 'whole blood' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1679563', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Omic_tissue': 'Whole Blood', 'p_SMR_multi': 2.139585e-15, 'p_HEIDI': 0.104475, 'A1': 'A', 'A2': 'C', 'Freq': 0.226994, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.31 | Q19 | Which SNP is most significantly associated with ALS in the Frontal Cortex? | There are no significantly associated SNPs with ALS in the Frontal Cortex. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND LOWER(Omic_tissue) = 'frontal cortex' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.85 | Q19 | Which SNP is most significantly associated with LBD in the Tibial Nerve? | There are no significantly associated SNPs with LBD in the Tibial Nerve. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND LOWER(Omic_tissue) = 'tibial nerve' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.68 | Q19 | Which SNP is most significantly associated with LBD in the Basal Ganglia? | There are no significantly associated SNPs with LBD in the Basal Ganglia. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND LOWER(Omic_tissue) = 'basal ganglia' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.10 | Q19 | Which SNP is most significantly associated with AD in the Hippocampus? | The most significantly associated SNP with AD in the Hippocampus is rs34130487, located in the STAG3 gene, with an adjusted SMR multi-SNP P-value of 2.18e-07 and a HEIDI value of 5.5343e-01. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND LOWER(Omic_tissue) = 'hippocampus' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1377707', 'topRSID': 'rs34130487', 'Disease': 'AD', 'Omic_tissue': 'Hippocampus', 'p_SMR_multi': 2.179524e-07, 'p_HEIDI': 0.5534318, 'A1': 'T', 'A2': 'C', 'Freq': 0.278119, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.34 | Q19 | Which SNP is most significantly associated with ALS in the Liver? | There are no significantly associated SNPs with ALS in the Liver. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND LOWER(Omic_tissue) = 'liver' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.67 | Q19 | Which SNP is most significantly associated with LBD in the Anterior Cingulate Cortex BA24? | There are no significantly associated SNPs with LBD in the Anterior Cingulate Cortex BA24. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND LOWER(Omic_tissue) = 'anterior cingulate cortex ba24' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT... | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.26 | Q19 | Which SNP is most significantly associated with ALS in the Caudate Basal Ganglia? | There are no significantly associated SNPs with ALS in the Caudate Basal Ganglia. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND LOWER(Omic_tissue) = 'caudate basal ganglia' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.75 | Q19 | Which SNP is most significantly associated with LBD in the Hippocampus? | There are no significantly associated SNPs with LBD in the Hippocampus. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND LOWER(Omic_tissue) = 'hippocampus' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.29 | Q19 | Which SNP is most significantly associated with ALS in the Cerebral Spinal Fluid? | There are no significantly associated SNPs with ALS in the Cerebral Spinal Fluid. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND LOWER(Omic_tissue) = 'cerebral spinal fluid' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.58 | Q19 | Which SNP is most significantly associated with FTD in the Prefrontal Cortex? | There are no significantly associated SNPs with FTD in the Prefrontal Cortex. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND LOWER(Omic_tissue) = 'prefrontal cortex' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.126 | Q19 | Which SNP is most significantly associated with PSP in the Tibial Nerve? | There are no significantly associated SNPs with PSP in the Tibial Nerve. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND LOWER(Omic_tissue) = 'tibial nerve' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.54 | Q19 | Which SNP is most significantly associated with FTD in the Hypothalamus? | There are no significantly associated SNPs with FTD in the Hypothalamus. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND LOWER(Omic_tissue) = 'hypothalamus' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.6 | Q19 | Which SNP is most significantly associated with AD in the Cerebellum? | The most significantly associated SNP with AD in the Cerebellum is rs34130487, located in the STAG3 gene, with an adjusted SMR multi-SNP P-value of 1.18e-09 and a HEIDI value of 4.0622e-01. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND LOWER(Omic_tissue) = 'cerebellum' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1687933', 'topRSID': 'rs34130487', 'Disease': 'AD', 'Omic_tissue': 'Cerebellum', 'p_SMR_multi': 1.184878e-09, 'p_HEIDI': 0.406217, 'A1': 'T', 'A2': 'C', 'Freq': 0.278119, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.69 | Q19 | Which SNP is most significantly associated with LBD in the Caudate Basal Ganglia? | There are no significantly associated SNPs with LBD in the Caudate Basal Ganglia. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND LOWER(Omic_tissue) = 'caudate basal ganglia' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.99 | Q19 | Which SNP is most significantly associated with PD in the Multi Ancestry Whole Brain? | The most significantly associated SNP with PD in the Multi Ancestry Whole Brain is rs55974014, located in the KANSL1-AS1 gene, with an adjusted SMR multi-SNP P-value of 5.69e-16 and a HEIDI value of 1.4916e-02. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND LOWER(Omic_tissue) = 'multi ancestry whole brain' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [{'UUID': 'NDD_SMR_genes_all_update_text_1435918', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Omic_tissue': 'Multi Ancestry Whole Brain', 'p_SMR_multi': 5.6905e-16, 'p_HEIDI': 0.01491641, 'A1': 'A', 'A2': 'C', 'Freq': 0.226994, 'func_sig': 'functionally significant'}] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
Q19.40 | Q19 | Which SNP is most significantly associated with ALS in the Spinalcord? | There are no significantly associated SNPs with ALS in the Spinalcord. | SELECT UUID, topRSID, Disease, Omic_tissue, p_SMR_multi, p_HEIDI, A1, A2, Freq, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND LOWER(Omic_tissue) = 'spinalcord' AND p_SMR_multi < 2.95e-6 AND p_HEIDI > 0.01
ORDER BY p_SMR_multi
LIMIT 1 | [] | refined | Select, Multi-Filter, Order By, Threshold | Functional Significance |
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