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Q34.1139
Q34
What are the names of the genes that are targeted by the drug Trametinib in the treatment of bronchial neoplasm?
Trametinib has not been approved by the FDA as a treatment for bronchial neoplasm, but it is currently undergoing evaluation in clinical trials for this purpose. However, the proposed gene target names are mitogen-activated protein kinase kinase 2 and mitogen-activated protein kinase kinase 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%bronchial neoplasm%" OR LOWER(efo_term) LIKE "%bronch...
[{'UUID': 'DrugTargetsIndication121923_text_928687', 'drugName': 'Trametinib', 'tradeNames_list': "['Mekinist']", 'syns_list': "['GSK-1120212', 'GSK1120212', 'JTP 74057', 'JTP-74057', 'TMT-212', 'TMT212Tmt212', 'Trametinib']", 'yearOfFirstApproval': -1, 'max_phase_for_ind': 1.0, 'mesh_heading': 'Bronchial Neoplasms', '...
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Q34.457
Q34
What are the names of the genes that are targeted by the drug Phenylephrine Hydrochloride in the treatment of seasonal allergic rhinitis?
In the context of seasonal allergic rhinitis, the drug Phenylephrine Hydrochloride targets the gene adrenoceptor alpha 1A, adrenoceptor alpha 1D and adrenoceptor alpha 1B.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%seasonal allergic rhinitis%" OR LOWER(efo_term) LIKE ...
[{'UUID': 'DrugTargetsIndication121923_text_416699', 'drugName': 'Phenylephrine Hydrochloride', 'tradeNames_list': "['Afrin 4 hour nasal spray', 'Biomydrin', 'Biorphen', 'Fenilfar', 'FenoxMydfrin', 'Nazex', 'Neo-synephrine', 'Neosynephrine', 'NostrilNurofen sinus pain relief', 'Phenylephrine hydrochloride', 'PrefrinVaz...
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Q34.1691
Q34
What are the names of the genes that are targeted by the drug Goserelin Acetate in the treatment of carcinoma?
In the context of carcinoma, the drug Goserelin Acetate targets the gene gonadotropin releasing hormone receptor.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%carcinoma%" OR LOWER(efo_term) LIKE "%carcinoma%") AN...
[{'UUID': 'DrugTargetsIndication121923_text_1096842', 'drugName': 'Goserelin Acetate', 'tradeNames_list': "['Novgos', 'Zoladex', 'Zoladex la']", 'syns_list': "['Fertilan', 'Goserelin Acetate', 'Goserelin acetate']", 'yearOfFirstApproval': 1989, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Carcinoma', 'efo_term': 'carcino...
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Q34.1499
Q34
What are the names of the genes that are targeted by the drug Methotrexate in the treatment of fungal infectious disease?
In the context of fungal infectious disease, the drug Methotrexate targets the gene dihydrofolate reductase.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%fungal infectious disease%" OR LOWER(efo_term) LIKE "...
[{'UUID': 'DrugTargetsIndication121923_text_1057600', 'drugName': 'Methotrexate', 'tradeNames_list': "['Amethopterin', 'Ebetrex', 'Emtexate high-pot', 'Emtexate pf', 'FolexMaxtrex', 'Methotrexate', 'Metoject', 'Mexate', 'Otrexup', 'Otrexup pfsRasuvo', 'Reditrex', 'Rheumatrex', 'Trexall', 'Zlatal']", 'syns_list': "['(r)...
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Q34.1187
Q34
What are the names of the genes that are targeted by the drug Fedratinib Hydrochloride in the treatment of primary myelofibrosis?
In the context of primary myelofibrosis, the drug Fedratinib Hydrochloride targets the gene fms related receptor tyrosine kinase 3 and Janus kinase 2.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%primary myelofibrosis%" OR LOWER(efo_term) LIKE "%pri...
[{'UUID': 'DrugTargetsIndication121923_text_933946', 'drugName': 'Fedratinib Hydrochloride', 'tradeNames_list': "['Inrebic']", 'syns_list': "['Fedratinib hydrochloride', 'SAR302503A']", 'yearOfFirstApproval': 2019, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Primary Myelofibrosis', 'efo_term': 'primary myelofibrosis', '...
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Q34.346
Q34
What are the names of the genes that are targeted by the drug Dexamethasone in the treatment of macular retinal edema?
In the context of macular retinal edema, the drug Dexamethasone targets the gene nuclear receptor subfamily 3 group C member 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%macular retinal edema%" OR LOWER(efo_term) LIKE "%mac...
[{'UUID': 'DrugTargetsIndication121923_text_227802', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex...
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Q34.1609
Q34
What are the names of the genes that are targeted by the drug Linaclotide in the treatment of constipation disorder?
In the context of constipation disorder, the drug Linaclotide targets the gene guanylate cyclase 2C.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%constipation disorder%" OR LOWER(efo_term) LIKE "%con...
[{'UUID': 'DrugTargetsIndication121923_text_1092109', 'drugName': 'Linaclotide', 'tradeNames_list': "['Constella', 'Linzess']", 'syns_list': "['ASP-0456', 'ASP0456', 'Linaclotide', 'MD-1100']", 'yearOfFirstApproval': 2012, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Constipation', 'efo_term': 'constipation disorder', 'a...
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Q34.1901
Q34
What are the names of the genes that are targeted by the drug Latanoprost in the treatment of open-angle glaucoma?
In the context of open-angle glaucoma, the drug Latanoprost targets the gene prostaglandin F receptor.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%open-angle glaucoma%" OR LOWER(efo_term) LIKE "%open-...
[{'UUID': 'DrugTargetsIndication121923_text_1149124', 'drugName': 'Latanoprost', 'tradeNames_list': "['Latanoprost', 'Monopost', 'Xalatan', 'Xelpros']", 'syns_list': "['Latanoprost', 'Latanoprost (isopropyl ester)', 'PHXA-41', 'PHXA41', 'T-2345T2345', 'XA-41', 'XA41']", 'yearOfFirstApproval': 1996, 'max_phase_for_ind':...
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Q34.929
Q34
What are the names of the genes that are targeted by the drug Ibuprofen in the treatment of Back pain?
In the context of Back pain, the drug Ibuprofen targets the gene prostaglandin-endoperoxide synthase 2 and prostaglandin-endoperoxide synthase 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%back pain%" OR LOWER(efo_term) LIKE "%back pain%") AN...
[{'UUID': 'DrugTargetsIndication121923_text_840001', 'drugName': 'Ibuprofen', 'tradeNames_list': '[\'Aches-n-pain\', \'Advil\', \'Advil liqui-gels\', \'Advil migraine liqui-gelsAnadin joint pain\', \'Anadin liquifast\', \'Anadin period pain reliefAnadin ultra\', \'Apsifen\', \'Apsifen-f\', \'Arthrofen 200\', \'Arthrofe...
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Q34.1043
Q34
What are the names of the genes that are targeted by the drug Levetiracetam in the treatment of Seizure?
In the context of Seizure, the drug Levetiracetam targets the gene calcium voltage-gated channel subunit alpha1 B and synaptic vesicle glycoprotein 2A.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%seizure%" OR LOWER(efo_term) LIKE "%seizure%") AND (L...
[{'UUID': 'DrugTargetsIndication121923_text_915126', 'drugName': 'Levetiracetam', 'tradeNames_list': "['Desitrend', 'Elepsia xr', 'Keppra', 'Keppra xr', 'LevetiracetamLevetiracetam in sodium chloride', 'Matever', 'Spritam']", 'syns_list': "['AGB-101', 'Elepsia', 'Levetiracetam', 'Levetiracetam accordLevetiracetam actav...
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Q34.1259
Q34
What are the names of the genes that are targeted by the drug Alpelisib in the treatment of breast cancer?
In the context of breast cancer, the drug Alpelisib targets the gene phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%breast cancer%" OR LOWER(efo_term) LIKE "%breast canc...
[{'UUID': 'DrugTargetsIndication121923_text_939631', 'drugName': 'Alpelisib', 'tradeNames_list': "['Piqray', 'Vijoice']", 'syns_list': "['Alpelisib', 'BYL-719', 'BYL719', 'Byl-719', 'NVP-BYL719', 'Vijoice']", 'yearOfFirstApproval': 2019, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Breast Neoplasms', 'efo_term': 'breast ...
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Q34.1331
Q34
What are the names of the genes that are targeted by the drug Ceritinib in the treatment of neoplasm?
In the context of neoplasm, the drug Ceritinib targets the gene ALK receptor tyrosine kinase, EMAP like 4 and nucleophosmin 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%neoplasm%" OR LOWER(efo_term) LIKE "%neoplasm%") AND ...
[{'UUID': 'DrugTargetsIndication121923_text_991833', 'drugName': 'Ceritinib', 'tradeNames_list': "['Zykadia']", 'syns_list': "['Ceritinib', 'Ceritinib[mi]', 'LDK-378', 'LDK378', 'NVP-LDK-378-NXNVP-LDK378-NX']", 'yearOfFirstApproval': 2014, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Neoplasms', 'efo_term': 'cancer', 'ap...
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Q34.1756
Q34
What are the names of the genes that are targeted by the drug Omeprazole in the treatment of gastric ulcer?
In the context of gastric ulcer, the drug Omeprazole targets the gene ATPase H+/K+ transporting subunit alpha and ATPase H+/K+ transporting subunit beta.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%gastric ulcer%" OR LOWER(efo_term) LIKE "%gastric ulc...
[{'UUID': 'DrugTargetsIndication121923_text_1098039', 'drugName': 'Omeprazole', 'tradeNames_list': "['Antra', 'Losec', 'Losec mups', 'Mezzopram', 'Mopral', 'Omeprazole', 'OmeranPrilosec', 'Zanprol']", 'syns_list': "['H 168/68', 'H-168/68', 'NSC-751450', 'NSC-759192', 'Omeprazole']", 'yearOfFirstApproval': 1989, 'max_ph...
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Q34.1659
Q34
What are the names of the genes that are targeted by the drug Spironolactone in the treatment of congestive heart failure?
In the context of congestive heart failure, the drug Spironolactone targets the gene nuclear receptor subfamily 3 group C member 2.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%congestive heart failure%" OR LOWER(efo_term) LIKE "%...
[{'UUID': 'DrugTargetsIndication121923_text_1094539', 'drugName': 'Spironolactone', 'tradeNames_list': "['Abbolactone', 'Aldactone', 'Carospir', 'Diatensec', 'Gx spironolLaractone', 'Spiretic', 'Spiroctan 100', 'Spiroctan 25', 'Spiroctan 50Spironolactone', 'Spirospare 100', 'Spirospare 25']", 'syns_list': "['NSC-150399...
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Q34.239
Q34
What are the names of the genes that are targeted by the drug Triamcinolone Acetonide in the treatment of rheumatoid arthritis?
In the context of rheumatoid arthritis, the drug Triamcinolone Acetonide targets the gene nuclear receptor subfamily 3 group C member 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%rheumatoid arthritis%" OR LOWER(efo_term) LIKE "%rheu...
[{'UUID': 'DrugTargetsIndication121923_text_222199', 'drugName': 'Triamcinolone Acetonide', 'tradeNames_list': "['Adcortyl', 'Adcortyl in orabase', 'Allernaze', 'Aristocort', 'Aristocort aAristogel', 'Audicort', 'Aureocort', 'Azmacort', 'Flutex', 'Gppe ear dps capGppe ear oint', 'Kenacort', 'Kenalog', 'Kenalog in oraba...
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Q34.1461
Q34
What are the names of the genes that are targeted by the drug Tazarotene in the treatment of psoriasis?
In the context of psoriasis, the drug Tazarotene targets the gene retinoic acid receptor gamma, retinoic acid receptor beta and retinoic acid receptor alpha.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%psoriasis%" OR LOWER(efo_term) LIKE "%psoriasis%") AN...
[{'UUID': 'DrugTargetsIndication121923_text_1055477', 'drugName': 'Tazarotene', 'tradeNames_list': "['Arazlo', 'Avage', 'Fabior', 'Tazorac', 'Zorac']", 'syns_list': "['AGN 190168', 'AGN-190168', 'Idp-123', 'Tazarotene']", 'yearOfFirstApproval': 1997, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Psoriasis', 'efo_term': 'p...
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Q34.1170
Q34
What are the names of the genes that are targeted by the drug Trametinib in the treatment of soft tissue sarcoma?
Trametinib has not been approved by the FDA as a treatment for soft tissue sarcoma, but it is currently undergoing evaluation in clinical trials for this purpose. However, the proposed gene target names are mitogen-activated protein kinase kinase 2 and mitogen-activated protein kinase kinase 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%soft tissue sarcoma%" OR LOWER(efo_term) LIKE "%soft ...
[{'UUID': 'DrugTargetsIndication121923_text_928718', 'drugName': 'Trametinib', 'tradeNames_list': "['Mekinist']", 'syns_list': "['GSK-1120212', 'GSK1120212', 'JTP 74057', 'JTP-74057', 'TMT-212', 'TMT212Tmt212', 'Trametinib']", 'yearOfFirstApproval': -1, 'max_phase_for_ind': 3.0, 'mesh_heading': 'Sarcoma', 'efo_term': '...
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Q34.1196
Q34
What are the names of the genes that are targeted by the drug Crizotinib in the treatment of diffuse large B-cell lymphoma?
In the context of diffuse large B-cell lymphoma, the drug Crizotinib targets the gene MET proto-oncogene, receptor tyrosine kinase, ALK receptor tyrosine kinase, EMAP like 4 and nucleophosmin 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%diffuse large b-cell lymphoma%" OR LOWER(efo_term) LI...
[{'UUID': 'DrugTargetsIndication121923_text_934398', 'drugName': 'Crizotinib', 'tradeNames_list': "['Xalkori']", 'syns_list': "['Crizotinib', 'NSC-756645', 'PF-02341066', 'PF-2341066', 'Pf-2341066']", 'yearOfFirstApproval': 2011, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Lymphoma, Large B-Cell, Diffuse', 'efo_term': '...
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Q34.419
Q34
What are the names of the genes that are targeted by the drug Fenofibrate in the treatment of Hypercholesterolemia?
In the context of Hypercholesterolemia, the drug Fenofibrate targets the gene peroxisome proliferator activated receptor alpha.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%hypercholesterolemia%" OR LOWER(efo_term) LIKE "%hype...
[{'UUID': 'DrugTargetsIndication121923_text_243842', 'drugName': 'Fenofibric Acid', 'tradeNames_list': "['Fenocor-67', 'Fenogal', 'Fibricor', 'Lipanthyl', 'Lipofen', 'LofibraSupralip', 'Trilipix']", 'syns_list': "['Fenofibrate free acid', 'Fenofibrate related compound bFenofibric acid', 'LF-153', 'NSC-281318', 'Proceto...
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Q34.113
Q34
What are the names of the genes that are targeted by the drug Duloxetine Hydrochloride in the treatment of neuropathic pain?
In the context of neuropathic pain, the drug Duloxetine Hydrochloride targets the gene solute carrier family 6 member 4 and solute carrier family 6 member 2.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%neuropathic pain%" OR LOWER(efo_term) LIKE "%neuropat...
[{'UUID': 'DrugTargetsIndication121923_text_206078', 'drugName': 'Duloxetine Hydrochloride', 'tradeNames_list': "['Ariclaim', 'Cymbalta', 'Drizalma sprinkle', 'DuciltiaDuloxetine hydrochloride', 'Yentreve']", 'syns_list': "['Ariclaim', 'Duloxetine (as hydrochloride)', 'Duloxetine hclDuloxetine hydrochloride', 'Duloxeti...
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Q34.625
Q34
What are the names of the genes that are targeted by the drug Sorafenib Tosylate in the treatment of chromophobe renal cell carcinoma?
In the context of chromophobe renal cell carcinoma, the drug Sorafenib Tosylate targets the gene kinase insert domain receptor, B-Raf proto-oncogene, serine/threonine kinase, fms related receptor tyrosine kinase 1, fms related receptor tyrosine kinase 3, KIT proto-oncogene, receptor tyrosine kinase, fms related recepto...
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%chromophobe renal cell carcinoma%" OR LOWER(efo_term)...
[{'UUID': 'DrugTargetsIndication121923_text_683536', 'drugName': 'Sorafenib Tosylate', 'tradeNames_list': "['Nexavar']", 'syns_list': "['BAY 54-9085', 'BAY-54-9085', 'Sorafenib tosilate', 'Sorafenib tosylate']", 'yearOfFirstApproval': 2005, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Carcinoma, Renal Cell', 'efo_term': ...
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Q34.539
Q34
What are the names of the genes that are targeted by the drug Azelastine Hydrochloride in the treatment of seasonal allergic rhinitis?
In the context of seasonal allergic rhinitis, the drug Azelastine Hydrochloride targets the gene histamine receptor H1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%seasonal allergic rhinitis%" OR LOWER(efo_term) LIKE ...
[{'UUID': 'DrugTargetsIndication121923_text_455906', 'drugName': 'Azelastine Hydrochloride', 'tradeNames_list': '[\'Astelin\', \'Astepro\', \'Astepro allergy\', "Azelastine hydrochlorideChildren\'s astepro allergyOptilast", \'Optivar\', \'RhinolastRhinolast allergy\']', 'syns_list': "['A-5610', 'Azelastine hcl', 'Azela...
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Q34.1484
Q34
What are the names of the genes that are targeted by the drug Methotrexate in the treatment of cancer?
In the context of cancer, the drug Methotrexate targets the gene dihydrofolate reductase.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%cancer%" OR LOWER(efo_term) LIKE "%cancer%") AND (LOW...
[{'UUID': 'DrugTargetsIndication121923_text_1058890', 'drugName': 'Methotrexate', 'tradeNames_list': "['Amethopterin', 'Ebetrex', 'Emtexate high-pot', 'Emtexate pf', 'FolexMaxtrex', 'Methotrexate', 'Metoject', 'Mexate', 'Otrexup', 'Otrexup pfsRasuvo', 'Reditrex', 'Rheumatrex', 'Trexall', 'Zlatal']", 'syns_list': "['(r)...
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Q34.1428
Q34
What are the names of the genes that are targeted by the drug Amlodipine Besylate in the treatment of Hypercholesterolemia?
In the context of Hypercholesterolemia, the drug Amlodipine Besylate targets the gene calcium voltage-gated channel subunit alpha1 C, calcium voltage-gated channel subunit alpha1 S, calcium voltage-gated channel subunit alpha1 D and calcium voltage-gated channel subunit alpha1 F.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%hypercholesterolemia%" OR LOWER(efo_term) LIKE "%hype...
[{'UUID': 'DrugTargetsIndication121923_text_1043698', 'drugName': 'Amlodipine Besylate', 'tradeNames_list': "['Amlodipine besylate', 'Norliqva', 'Norvasc']", 'syns_list': "['Amlodipine (as besilate)', 'Amlodipine benzenesulfonateAmlodipine besilate', 'Amlodipine besylate', 'Amlor', 'AntacalLodipressin', 'Monopina', 'NS...
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Q34.1431
Q34
What are the names of the genes that are targeted by the drug Amlodipine Besylate in the treatment of myocardial infarction?
In the context of myocardial infarction, the drug Amlodipine Besylate targets the gene calcium voltage-gated channel subunit alpha1 C, calcium voltage-gated channel subunit alpha1 S, calcium voltage-gated channel subunit alpha1 D and calcium voltage-gated channel subunit alpha1 F.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%myocardial infarction%" OR LOWER(efo_term) LIKE "%myo...
[{'UUID': 'DrugTargetsIndication121923_text_1043735', 'drugName': 'Amlodipine Besylate', 'tradeNames_list': "['Amlodipine besylate', 'Norliqva', 'Norvasc']", 'syns_list': "['Amlodipine (as besilate)', 'Amlodipine benzenesulfonateAmlodipine besilate', 'Amlodipine besylate', 'Amlor', 'AntacalLodipressin', 'Monopina', 'NS...
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Q34.1064
Q34
What are the names of the genes that are targeted by the drug Imiquimod in the treatment of skin basal cell carcinoma?
In the context of skin basal cell carcinoma, the drug Imiquimod targets the gene toll like receptor 7.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%skin basal cell carcinoma%" OR LOWER(efo_term) LIKE "...
[{'UUID': 'DrugTargetsIndication121923_text_919782', 'drugName': 'Imiquimod', 'tradeNames_list': "['Aldara', 'Imiquimod', 'Zyclara']", 'syns_list': "['Aldara', 'Imiquimod', 'NSC-369100', 'NSC-759651', 'R-837', 'S-26308', 'S26308Tmx-101']", 'yearOfFirstApproval': 1997, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Carcinom...
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Q34.761
Q34
What are the names of the genes that are targeted by the drug Naltrexone in the treatment of alcohol abuse?
In the context of alcohol abuse, the drug Naltrexone targets the gene opioid receptor mu 1, opioid receptor kappa 1 and opioid receptor delta 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%alcohol abuse%" OR LOWER(efo_term) LIKE "%alcohol abu...
[{'UUID': 'DrugTargetsIndication121923_text_785289', 'drugName': 'Naltrexone', 'tradeNames_list': "['Celupan', 'Trexal', 'Trexan', 'Vivitrol']", 'syns_list': "['EN-1639A', 'EN-1639A FREE BASE', 'EN-1639A [AS HYDROCHLORIDE]NSC-758439', 'Naltrexone', 'Revia']", 'yearOfFirstApproval': 1984, 'max_phase_for_ind': 4.0, 'mesh...
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Q34.1519
Q34
What are the names of the genes that are targeted by the drug Telmisartan in the treatment of diabetes mellitus?
In the context of diabetes mellitus, the drug Telmisartan targets the gene angiotensin II receptor type 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%diabetes mellitus%" OR LOWER(efo_term) LIKE "%diabete...
[{'UUID': 'DrugTargetsIndication121923_text_1072709', 'drugName': 'Telmisartan', 'tradeNames_list': "['Micardis', 'Telmisartan', 'Tolura']", 'syns_list': "['BIBR 277 SE', 'BIBR-277', 'BIBR-277 SE', 'BIBR-277-SE', 'BIBR-277SEC09CA07', 'Kinzalmono', 'Pritor', 'Semintra', 'TelmisartanTelmisartan actavis', 'Telmisartan tev...
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Q34.1628
Q34
What are the names of the genes that are targeted by the drug Dabigatran in the treatment of Respiratory Syncytial Virus Infection?
Dabigatran has not been approved by the FDA as a treatment for Respiratory Syncytial Virus Infection, but it is currently undergoing evaluation in clinical trials for this purpose. However, the proposed gene target name is coagulation factor II, thrombin.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%respiratory syncytial virus infection%" OR LOWER(efo_...
[{'UUID': 'DrugTargetsIndication121923_text_1093461', 'drugName': 'Dabigatran', 'tradeNames_list': "['Pradaxa']", 'syns_list': "['BIBR 953 ZW', 'BIBR-953', 'BIBR-953-ZW', 'DabigatranPradaxa (dabigatran)']", 'yearOfFirstApproval': -1, 'max_phase_for_ind': 1.0, 'mesh_heading': 'Respiratory Syncytial Virus Infections', 'e...
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Q34.1593
Q34
What are the names of the genes that are targeted by the drug Tacrolimus in the treatment of immune system disease?
In the context of immune system disease, the drug Tacrolimus targets the gene FKBP prolyl isomerase 1A.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%immune system disease%" OR LOWER(efo_term) LIKE "%imm...
[{'UUID': 'DrugTargetsIndication121923_text_1091477', 'drugName': 'Tacrolimus', 'tradeNames_list': "['Adoport', 'Advagraf', 'Astagraf xl', 'Capexion', 'Envarsus', 'Envarsus xrModigraf', 'Perixis', 'Prograf', 'Protopic', 'Tacni', 'Tacrolimus', 'Vivadex']", 'syns_list': "['FK 506', 'FR900506', 'Tacrolimus', 'Tacrolimus h...
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Q34.930
Q34
What are the names of the genes that are targeted by the drug Ibuprofen in the treatment of Dysmenorrhea?
In the context of Dysmenorrhea, the drug Ibuprofen targets the gene prostaglandin-endoperoxide synthase 2 and prostaglandin-endoperoxide synthase 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%dysmenorrhea%" OR LOWER(efo_term) LIKE "%dysmenorrhea...
[{'UUID': 'DrugTargetsIndication121923_text_840160', 'drugName': 'Ibuprofen', 'tradeNames_list': '[\'Aches-n-pain\', \'Advil\', \'Advil liqui-gels\', \'Advil migraine liqui-gelsAnadin joint pain\', \'Anadin liquifast\', \'Anadin period pain reliefAnadin ultra\', \'Apsifen\', \'Apsifen-f\', \'Arthrofen 200\', \'Arthrofe...
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Q34.1654
Q34
What are the names of the genes that are targeted by the drug Abiraterone Acetate in the treatment of prostate carcinoma?
In the context of prostate carcinoma, the drug Abiraterone Acetate targets the gene cytochrome P450 family 17 subfamily A member 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%prostate carcinoma%" OR LOWER(efo_term) LIKE "%prosta...
[{'UUID': 'DrugTargetsIndication121923_text_1094287', 'drugName': 'Abiraterone Acetate', 'tradeNames_list': "['Yonsa', 'Zytiga']", 'syns_list': "['Abiraterone acetate', 'CB-7630', 'CB7630', 'NSC-748121', 'NSC-749227']", 'yearOfFirstApproval': 2011, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Prostatic Neoplasms', 'efo_t...
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Q34.1304
Q34
What are the names of the genes that are targeted by the drug Nitroglycerin in the treatment of congestive heart failure?
In the context of congestive heart failure, the drug Nitroglycerin targets the gene guanylate cyclase 1 soluble subunit beta 1, guanylate cyclase 1 soluble subunit beta 2 (pseudogene), guanylate cyclase 1 soluble subunit alpha 2 and guanylate cyclase 1 soluble subunit alpha 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%congestive heart failure%" OR LOWER(efo_term) LIKE "%...
[{'UUID': 'DrugTargetsIndication121923_text_972645', 'drugName': 'Nitroglycerin', 'tradeNames_list': "['Coro-nitro', 'Deponit 10', 'Deponit 5', 'Glytrin', 'Gonitro', 'Lenitral 7.5Minitran', 'Minitran 10', 'Minitran 15', 'Minitran 5', 'NatiroseNitriderm tts', 'Nitro iv', 'Nitro-bid', 'Nitro-dur', 'Nitro-mack retNitrocin...
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Q34.1831
Q34
What are the names of the genes that are targeted by the drug Cyclosporine in the treatment of keratoconjunctivitis?
In the context of keratoconjunctivitis, the drug Cyclosporine targets the gene peptidylprolyl isomerase A.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%keratoconjunctivitis%" OR LOWER(efo_term) LIKE "%kera...
[{'UUID': 'DrugTargetsIndication121923_text_1101284', 'drugName': 'Cyclosporine', 'tradeNames_list': "['Capimune', 'Capsorin', 'Cequa', 'Cyclosporine', 'Deximune', 'GengrafIkervis', 'Neoral', 'Optimmune', 'Restasis', 'Restasis multidoseSandimmun', 'Sandimmune', 'Sangcya', 'Vanquoral', 'Verkazia']", 'syns_list': "['27-4...
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Q34.431
Q34
What are the names of the genes that are targeted by the drug Selexipag in the treatment of idiopathic pulmonary arterial hypertension?
In the context of idiopathic pulmonary arterial hypertension, the drug Selexipag targets the gene prostaglandin I2 receptor.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%idiopathic pulmonary arterial hypertension%" OR LOWER...
[{'UUID': 'DrugTargetsIndication121923_text_246146', 'drugName': 'Selexipag', 'tradeNames_list': "['Uptravi']", 'syns_list': "['ACT-293987', 'NS-304', 'Selexipag']", 'yearOfFirstApproval': 2015, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Familial Primary Pulmonary Hypertension', 'efo_term': 'idiopathic pulmonary arteri...
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Q34.1173
Q34
What are the names of the genes that are targeted by the drug Selumetinib Sulfate in the treatment of neurofibromatosis type 1?
In the context of neurofibromatosis type 1, the drug Selumetinib Sulfate targets the gene mitogen-activated protein kinase kinase 2 and mitogen-activated protein kinase kinase 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%neurofibromatosis type 1%" OR LOWER(efo_term) LIKE "%...
[{'UUID': 'DrugTargetsIndication121923_text_932837', 'drugName': 'Selumetinib Sulfate', 'tradeNames_list': "['Koselugo']", 'syns_list': "['AZD-6244 HYD-SULFATE', 'AZD-6244 HYDROGEN SULFATE', 'AZD6244 HYD-SULFATEAZD6244 HYDROGEN SULFATE', 'Azd-6244 hydrogen sulphateAzd6244 hydrogen sulphate', 'Selumetinib sulfate', 'Sel...
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Q34.709
Q34
What are the names of the genes that are targeted by the drug Nilotinib in the treatment of cancer?
In the context of cancer, the drug Nilotinib targets the gene ABL proto-oncogene 1, non-receptor tyrosine kinase and BCR activator of RhoGEF and GTPase.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%cancer%" OR LOWER(efo_term) LIKE "%cancer%") AND (LOW...
[{'UUID': 'DrugTargetsIndication121923_text_747506', 'drugName': 'Nilotinib', 'tradeNames_list': "['Tasigna']", 'syns_list': "['AMN 107', 'AMN-107', 'AMN107', 'NSC-747599', 'Nilotinib']", 'yearOfFirstApproval': 2007, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Neoplasms', 'efo_term': 'cancer', 'approvedSymbol': 'ABL1', ...
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Q34.1230
Q34
What are the names of the genes that are targeted by the drug Ribavirin in the treatment of fibrosis?
In the context of fibrosis, the drug Ribavirin targets the gene inosine monophosphate dehydrogenase 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%fibrosis%" OR LOWER(efo_term) LIKE "%fibrosis%") AND ...
[{'UUID': 'DrugTargetsIndication121923_text_937567', 'drugName': 'Ribavirin', 'tradeNames_list': "['Copegus', 'Rebetol', 'Ribapak', 'Ribasphere', 'Ribavarin', 'RibavirinRibofluranosyl Carboxamide', 'Tribavirin', 'Viramid', 'Virazid', 'Virazole']", 'syns_list': "['Cotronak', 'NSC-163039', 'Ribavirin', 'Ribavirin biopart...
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Q34.1530
Q34
What are the names of the genes that are targeted by the drug Aprepitant in the treatment of Chemotherapy-induced nausea and vomiting?
In the context of Chemotherapy-induced nausea and vomiting, the drug Aprepitant targets the gene tachykinin receptor 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%chemotherapy-induced nausea and vomiting%" OR LOWER(e...
[{'UUID': 'DrugTargetsIndication121923_text_1072807', 'drugName': 'Aprepitant', 'tradeNames_list': "['Aprepitant', 'Cinvanti', 'Emend']", 'syns_list': "['Aprepitant', 'L-754,030', 'MK-0869', 'MK-869', 'NSC-748825']", 'yearOfFirstApproval': 2003, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Postoperative Nausea and Vomiti...
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Q34.559
Q34
What are the names of the genes that are targeted by the drug Lidocaine Hydrochloride in the treatment of prostate carcinoma?
In the context of prostate carcinoma, the drug Lidocaine Hydrochloride targets the gene sodium voltage-gated channel alpha subunit 1, sodium voltage-gated channel alpha subunit 5, sodium voltage-gated channel alpha subunit 4, sodium voltage-gated channel alpha subunit 7, sodium voltage-gated channel alpha subunit 2, so...
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%prostate carcinoma%" OR LOWER(efo_term) LIKE "%prosta...
[{'UUID': 'DrugTargetsIndication121923_text_637008', 'drugName': 'Lidocaine Hydrochloride', 'tradeNames_list': "['Akten', 'Alphacaine hydrochloride', 'Anestacon', 'Anodesyn', 'BismodyneBradosol plus', 'Calgel', 'Co-phenylcaine fte', 'Denela', 'DequasprayEmla', 'Germoloids', 'Germoloids complete', 'Glydo', 'Hemocane', '...
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Q34.1549
Q34
What are the names of the genes that are targeted by the drug Lemborexant in the treatment of insomnia?
In the context of insomnia, the drug Lemborexant targets the gene hypocretin receptor 2 and hypocretin receptor 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%insomnia%" OR LOWER(efo_term) LIKE "%insomnia%") AND ...
[{'UUID': 'DrugTargetsIndication121923_text_1076427', 'drugName': 'Lemborexant', 'tradeNames_list': "['Dayvigo']", 'syns_list': "['E-2006', 'E2006', 'Lemborexant']", 'yearOfFirstApproval': 2020, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Sleep Initiation and Maintenance Disorders', 'efo_term': 'insomnia', 'approvedSymb...
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Q34.354
Q34
What are the names of the genes that are targeted by the drug Dexamethasone in the treatment of sarcoidosis?
In the context of sarcoidosis, the drug Dexamethasone targets the gene nuclear receptor subfamily 3 group C member 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%sarcoidosis%" OR LOWER(efo_term) LIKE "%sarcoidosis%"...
[{'UUID': 'DrugTargetsIndication121923_text_227810', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex...
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Q34.1366
Q34
What are the names of the genes that are targeted by the drug Ibrutinib in the treatment of Mantle cell lymphoma?
In the context of Mantle cell lymphoma, the drug Ibrutinib targets the gene Bruton tyrosine kinase.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%mantle cell lymphoma%" OR LOWER(efo_term) LIKE "%mant...
[{'UUID': 'DrugTargetsIndication121923_text_995267', 'drugName': 'Ibrutinib', 'tradeNames_list': "['Imbruvica']", 'syns_list': "['CRA-032765', 'Ibrutinib', 'PC-32765', 'PCI 32765', 'PCI-32765PCI-32765-00']", 'yearOfFirstApproval': 2013, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Lymphoma, Mantle-Cell', 'efo_term': 'Man...
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Q34.851
Q34
What are the names of the genes that are targeted by the drug Celecoxib in the treatment of peptic ulcer disease?
In the context of peptic ulcer disease, the drug Celecoxib targets the gene prostaglandin-endoperoxide synthase 2.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%peptic ulcer disease%" OR LOWER(efo_term) LIKE "%pept...
[{'UUID': 'DrugTargetsIndication121923_text_833504', 'drugName': 'Celecoxib', 'tradeNames_list': "['Celebra', 'Celebrex', 'Celecoxib', 'Elyxyb', 'Onsenal']", 'syns_list': "['Celecoxib', 'DFN-15', 'DFN15', 'NSC-719627', 'NSC-758624', 'SC-58635']", 'yearOfFirstApproval': 1998, 'max_phase_for_ind': 4.0, 'mesh_heading': 'P...
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Q34.1591
Q34
What are the names of the genes that are targeted by the drug Temsirolimus in the treatment of renal cell carcinoma?
In the context of renal cell carcinoma, the drug Temsirolimus targets the gene FKBP prolyl isomerase 1A.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%renal cell carcinoma%" OR LOWER(efo_term) LIKE "%rena...
[{'UUID': 'DrugTargetsIndication121923_text_1091090', 'drugName': 'Temsirolimus', 'tradeNames_list': "['Torisel']", 'syns_list': "['CCI-779', 'Temsirolimus']", 'yearOfFirstApproval': 2007, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Carcinoma, Renal Cell', 'efo_term': 'renal cell carcinoma', 'approvedSymbol': 'FKBP1A', ...
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Q34.101
Q34
What are the names of the genes that are targeted by the drug Granisetron in the treatment of post operative nausea and vomiting?
In the context of post operative nausea and vomiting, the drug Granisetron targets the gene 5-hydroxytryptamine receptor 3A.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%post operative nausea and vomiting%" OR LOWER(efo_ter...
[{'UUID': 'DrugTargetsIndication121923_text_205822', 'drugName': 'Granisetron', 'tradeNames_list': "['Kytril', 'Sancuso', 'Sustol']", 'syns_list': "['APF-530', 'APF530', 'BRL 43694', 'BRL-43694', 'Granisetron', 'LY-278584']", 'yearOfFirstApproval': 1993, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Postoperative Nausea a...
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Q34.222
Q34
What are the names of the genes that are targeted by the drug Desoximetasone in the treatment of psoriasis vulgaris?
In the context of psoriasis vulgaris, the drug Desoximetasone targets the gene nuclear receptor subfamily 3 group C member 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%psoriasis vulgaris%" OR LOWER(efo_term) LIKE "%psoria...
[{'UUID': 'DrugTargetsIndication121923_text_220822', 'drugName': 'Desoximetasone', 'tradeNames_list': "['Desoximetasone', 'Stiedex', 'Stiedex lp', 'Stiedex lpn', 'TopicortTopicort lp']", 'syns_list': "['A-41-304', 'A-41304', 'Desoximetasone', 'Desoxymethasone', 'HOE 304HOE-304', 'J83.644C', 'NSC-759189', 'R 2113', 'R-2...
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Q34.1904
Q34
What are the names of the genes that are targeted by the drug Bimatoprost in the treatment of open-angle glaucoma?
In the context of open-angle glaucoma, the drug Bimatoprost targets the gene prostaglandin F receptor.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%open-angle glaucoma%" OR LOWER(efo_term) LIKE "%open-...
[{'UUID': 'DrugTargetsIndication121923_text_1149175', 'drugName': 'Bimatoprost', 'tradeNames_list': "['Bimatoprost', 'Durysta', 'Latisse', 'Lumigan']", 'syns_list': "['AGN 192024', 'AGN-192024', 'Bimatoprost', 'Prostamide']", 'yearOfFirstApproval': 2001, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Glaucoma, Open-Angle',...
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Q34.699
Q34
What are the names of the genes that are targeted by the drug Apixaban in the treatment of deep vein thrombosis?
In the context of deep vein thrombosis, the drug Apixaban targets the gene coagulation factor X.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%deep vein thrombosis%" OR LOWER(efo_term) LIKE "%deep...
[{'UUID': 'DrugTargetsIndication121923_text_710509', 'drugName': 'Apixaban', 'tradeNames_list': "['Eliquis']", 'syns_list': "['Apixaban', 'BMS-562247', 'BMS-562247-01']", 'yearOfFirstApproval': 2012, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Venous Thrombosis', 'efo_term': 'deep vein thrombosis', 'approvedSymbol': 'F1...
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Q34.1638
Q34
What are the names of the genes that are targeted by the drug Atogepant in the treatment of migraine disorder?
In the context of migraine disorder, the drug Atogepant targets the gene calcitonin receptor like receptor.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%migraine disorder%" OR LOWER(efo_term) LIKE "%migrain...
[{'UUID': 'DrugTargetsIndication121923_text_1094046', 'drugName': 'Atogepant', 'tradeNames_list': "['Qulipta']", 'syns_list': "['AGN-241689', 'Atogepant', 'MK-8031']", 'yearOfFirstApproval': 2021, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Migraine Disorders', 'efo_term': 'migraine disorder', 'approvedSymbol': 'CALCRL'...
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Q34.1370
Q34
What are the names of the genes that are targeted by the drug Zanubrutinib in the treatment of neoplasm?
In the context of neoplasm, the drug Zanubrutinib targets the gene Bruton tyrosine kinase.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%neoplasm%" OR LOWER(efo_term) LIKE "%neoplasm%") AND ...
[{'UUID': 'DrugTargetsIndication121923_text_1025140', 'drugName': 'Zanubrutinib', 'tradeNames_list': "['Brukinsa']", 'syns_list': "['BGB-3111', 'Bgb-3111', 'Zanubrutinib']", 'yearOfFirstApproval': 2019, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Neoplasms', 'efo_term': 'neoplasm', 'approvedSymbol': 'BTK', 'approvedName...
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Q34.1712
Q34
What are the names of the genes that are targeted by the drug Triptorelin Pamoate in the treatment of Central precocious puberty?
In the context of Central precocious puberty, the drug Triptorelin Pamoate targets the gene gonadotropin releasing hormone receptor.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%central precocious puberty%" OR LOWER(efo_term) LIKE ...
[{'UUID': 'DrugTargetsIndication121923_text_1097287', 'drugName': 'Triptorelin Pamoate', 'tradeNames_list': "['Trelstar', 'Triptodur kit']", 'syns_list': "['Salvacyl', 'Triptorelin (as embonate)', 'Triptorelin embonateTriptorelin pamoate']", 'yearOfFirstApproval': 2000, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Pubert...
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Q34.1017
Q34
What are the names of the genes that are targeted by the drug Glycopyrrolate in the treatment of gastrointestinal disease?
In the context of gastrointestinal disease, the drug Glycopyrrolate targets the gene cholinergic receptor muscarinic 3 and cholinergic receptor muscarinic 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%gastrointestinal disease%" OR LOWER(efo_term) LIKE "%...
[{'UUID': 'DrugTargetsIndication121923_text_857535', 'drugName': 'Glycopyrrolate', 'tradeNames_list': "['Cuvposa', 'Dartisla odt', 'Glycopyrrolate', 'Glyrx-pfLonhala magnair kit', 'Robinul', 'Robinul forte', 'Robinul fte', 'SeebriSialanar']", 'syns_list': "['AD-237', 'AHR-504', 'CHF-5259', 'CHF5259', 'GlycopyrrolateGly...
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Q34.318
Q34
What are the names of the genes that are targeted by the drug Dexamethasone in the treatment of eosinophilic pneumonia?
In the context of eosinophilic pneumonia, the drug Dexamethasone targets the gene nuclear receptor subfamily 3 group C member 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%eosinophilic pneumonia%" OR LOWER(efo_term) LIKE "%eo...
[{'UUID': 'DrugTargetsIndication121923_text_227774', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex...
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Q34.130
Q34
What are the names of the genes that are targeted by the drug Vilazodone Hydrochloride in the treatment of unipolar depression?
In the context of unipolar depression, the drug Vilazodone Hydrochloride targets the gene solute carrier family 6 member 4 and 5-hydroxytryptamine receptor 1A.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%unipolar depression%" OR LOWER(efo_term) LIKE "%unipo...
[{'UUID': 'DrugTargetsIndication121923_text_207060', 'drugName': 'Vilazodone Hydrochloride', 'tradeNames_list': "['Viibryd']", 'syns_list': "['EMD 68 843', 'EMD-68843', 'SB-659746-A', 'SB659746-A', 'Vilazodone hclVilazodone hydrochloride']", 'yearOfFirstApproval': 2011, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Depres...
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Q34.894
Q34
What are the names of the genes that are targeted by the drug Naproxen Sodium in the treatment of juvenile idiopathic arthritis?
In the context of juvenile idiopathic arthritis, the drug Naproxen Sodium targets the gene prostaglandin-endoperoxide synthase 2 and prostaglandin-endoperoxide synthase 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%juvenile idiopathic arthritis%" OR LOWER(efo_term) LI...
[{'UUID': 'DrugTargetsIndication121923_text_838130', 'drugName': 'Naproxen Sodium', 'tradeNames_list': "['Aleve', 'Anaprox', 'Anaprox ds', 'Naprelan', 'Naproxen sodium', 'Synflex']", 'syns_list': "['BAY-117031', 'BAY117031', 'BAYH6689', 'Naproxen sodiumNaproxen sodium anhydrous', 'Naproxen sodium salt', 'RS-3650']", 'y...
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Q34.212
Q34
What are the names of the genes that are targeted by the drug Prednisone in the treatment of asthma?
In the context of asthma, the drug Prednisone targets the gene nuclear receptor subfamily 3 group C member 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%asthma%" OR LOWER(efo_term) LIKE "%asthma%") AND (LOW...
[{'UUID': 'DrugTargetsIndication121923_text_218718', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",...
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Q34.1235
Q34
What are the names of the genes that are targeted by the drug Mirabegron in the treatment of Urinary incontinence?
In the context of Urinary incontinence, the drug Mirabegron targets the gene adrenoceptor beta 3.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%urinary incontinence%" OR LOWER(efo_term) LIKE "%urin...
[{'UUID': 'DrugTargetsIndication121923_text_937726', 'drugName': 'Mirabegron', 'tradeNames_list': "['Betmiga', 'Myrbetriq', 'Myrbetriq granules']", 'syns_list': "['Betanis', 'Mirabegron', 'YM-178', 'YM178']", 'yearOfFirstApproval': 2012, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Urinary Incontinence, Urge', 'efo_term'...
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Q34.1916
Q34
What are the names of the genes that are targeted by the drug Teriflunomide in the treatment of immune system disease?
In the context of immune system disease, the drug Teriflunomide targets the gene dihydroorotate dehydrogenase (quinone).
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%immune system disease%" OR LOWER(efo_term) LIKE "%imm...
[{'UUID': 'DrugTargetsIndication121923_text_1191752', 'drugName': 'Teriflunomide', 'tradeNames_list': "['Aubagio']", 'syns_list': "['A77 1726', 'HMR-1726', 'HMR1726', 'Leflunomide related compound bLeflunomide related compound b rs', 'Teriflunomide']", 'yearOfFirstApproval': 2012, 'max_phase_for_ind': 4.0, 'mesh_headin...
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Q34.584
Q34
What are the names of the genes that are targeted by the drug Erlosamide in the treatment of epilepsy?
In the context of epilepsy, the drug Erlosamide targets the gene sodium voltage-gated channel alpha subunit 1, sodium voltage-gated channel alpha subunit 5, sodium voltage-gated channel alpha subunit 4, sodium voltage-gated channel alpha subunit 7, sodium voltage-gated channel alpha subunit 2, sodium voltage-gated chan...
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%epilepsy%" OR LOWER(efo_term) LIKE "%epilepsy%") AND ...
[{'UUID': 'DrugTargetsIndication121923_text_646292', 'drugName': 'Erlosamide', 'tradeNames_list': "['Lacosamide', 'Vimpat']", 'syns_list': "['(r)-lacosamide 1', 'ADD 243037', 'ADD-243037', 'Erlosamide', 'LacosamideLacosamide cv', 'SPM 927', 'SPM-927']", 'yearOfFirstApproval': 2008, 'max_phase_for_ind': 4.0, 'mesh_headi...
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Q34.436
Q34
What are the names of the genes that are targeted by the drug Carvedilol in the treatment of heart failure?
In the context of heart failure, the drug Carvedilol targets the gene adrenoceptor alpha 1A, adrenoceptor beta 2, adrenoceptor beta 1, adrenoceptor beta 3, adrenoceptor alpha 1D and adrenoceptor alpha 1B.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%heart failure%" OR LOWER(efo_term) LIKE "%heart failu...
[{'UUID': 'DrugTargetsIndication121923_text_357043', 'drugName': 'Carvedilol', 'tradeNames_list': "['Carvedilol', 'Coreg', 'Coreg CR', 'Eucardic 12.5', 'Eucardic 25Eucardic 3.125', 'Eucardic 6.25']", 'syns_list': "['BM 14.190', 'BM-14-190', 'BM-14.190', 'BM-14190', 'C07AG02', 'CarvedilolCoronis', 'DQ-2466', 'Dilatrend'...
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Q34.1091
Q34
What are the names of the genes that are targeted by the drug Apalutamide in the treatment of prostate cancer?
In the context of prostate cancer, the drug Apalutamide targets the gene androgen receptor.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%prostate cancer%" OR LOWER(efo_term) LIKE "%prostate ...
[{'UUID': 'DrugTargetsIndication121923_text_921863', 'drugName': 'Apalutamide', 'tradeNames_list': "['Erleada']", 'syns_list': "['ARN-509', 'Apalutamide', 'Arn-509', 'JNJ-56021927']", 'yearOfFirstApproval': 2018, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Prostatic Neoplasms', 'efo_term': 'prostate cancer', 'approvedSy...
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Q34.486
Q34
What are the names of the genes that are targeted by the drug Lisdexamfetamine Dimesylate in the treatment of drug dependence?
In the context of drug dependence, the drug Lisdexamfetamine Dimesylate targets the gene solute carrier family 6 member 2, solute carrier family 18 member A2 and solute carrier family 6 member 3.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%drug dependence%" OR LOWER(efo_term) LIKE "%drug depe...
[{'UUID': 'DrugTargetsIndication121923_text_419193', 'drugName': 'Lisdexamfetamine Dimesylate', 'tradeNames_list': "['Elvanse', 'Elvanse adult', 'Vyvanse']", 'syns_list': "['Lisdexamfetamine dimesilate', 'Lisdexamfetamine dimesylateLisdexamfetamine dimethanesulfonate', 'Lisdexamfetamine mesilateLisdexamphetamine dimesi...
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Q34.213
Q34
What are the names of the genes that are targeted by the drug Prednisone in the treatment of osteoarthritis?
In the context of osteoarthritis, the drug Prednisone targets the gene nuclear receptor subfamily 3 group C member 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%osteoarthritis%" OR LOWER(efo_term) LIKE "%osteoarthr...
[{'UUID': 'DrugTargetsIndication121923_text_218719', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",...
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Q34.720
Q34
What are the names of the genes that are targeted by the drug Vemurafenib in the treatment of metastatic melanoma?
In the context of metastatic melanoma, the drug Vemurafenib targets the gene B-Raf proto-oncogene, serine/threonine kinase.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%metastatic melanoma%" OR LOWER(efo_term) LIKE "%metas...
[{'UUID': 'DrugTargetsIndication121923_text_752203', 'drugName': 'Vemurafenib', 'tradeNames_list': "['Zelboraf']", 'syns_list': "['PLX-4032', 'PLX4032', 'RG 7204', 'RG-7204', 'RO 5185426', 'RO-51-85426RO-5185426', 'Vemurafenib']", 'yearOfFirstApproval': 2011, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Melanoma', 'efo_t...
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Q34.531
Q34
What are the names of the genes that are targeted by the drug Carbinoxamine Maleate in the treatment of urticaria?
In the context of urticaria, the drug Carbinoxamine Maleate targets the gene histamine receptor H1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%urticaria%" OR LOWER(efo_term) LIKE "%urticaria%") AN...
[{'UUID': 'DrugTargetsIndication121923_text_455849', 'drugName': 'Carbinoxamine Maleate', 'tradeNames_list': "['Carbinoxamine maleate', 'Clistin', 'Davenol', 'Karbinal er']", 'syns_list': "['Carbinoxamine maleate', 'NSC-62362']", 'yearOfFirstApproval': 2003, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Urticaria', 'efo_t...
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Q34.214
Q34
What are the names of the genes that are targeted by the drug Prednisone in the treatment of multiple sclerosis?
In the context of multiple sclerosis, the drug Prednisone targets the gene nuclear receptor subfamily 3 group C member 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%multiple sclerosis%" OR LOWER(efo_term) LIKE "%multip...
[{'UUID': 'DrugTargetsIndication121923_text_218096', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",...
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Q34.776
Q34
What are the names of the genes that are targeted by the drug Hydromorphone Hydrochloride in the treatment of drug dependence?
In the context of drug dependence, the drug Hydromorphone Hydrochloride targets the gene opioid receptor mu 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%drug dependence%" OR LOWER(efo_term) LIKE "%drug depe...
[{'UUID': 'DrugTargetsIndication121923_text_792050', 'drugName': 'Hydromorphone Hydrochloride', 'tradeNames_list': "['Dilaudid', 'Dilaudid-hp', 'Exalgo', 'Hydromorphone hydrochloridePalladone', 'Palladone-sr']", 'syns_list': "['Dihydromorphinone hydrochloride', 'Hydromorphone HCl', 'Hydromorphone hclHydromorphone hydro...
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Q34.326
Q34
What are the names of the genes that are targeted by the drug Dexamethasone in the treatment of myocarditis?
In the context of myocarditis, the drug Dexamethasone targets the gene nuclear receptor subfamily 3 group C member 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%myocarditis%" OR LOWER(efo_term) LIKE "%myocarditis%"...
[{'UUID': 'DrugTargetsIndication121923_text_227782', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex...
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Q34.844
Q34
What are the names of the genes that are targeted by the drug Celecoxib in the treatment of stroke?
In the context of stroke, the drug Celecoxib targets the gene prostaglandin-endoperoxide synthase 2.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%stroke%" OR LOWER(efo_term) LIKE "%stroke%") AND (LOW...
[{'UUID': 'DrugTargetsIndication121923_text_833495', 'drugName': 'Celecoxib', 'tradeNames_list': "['Celebra', 'Celebrex', 'Celecoxib', 'Elyxyb', 'Onsenal']", 'syns_list': "['Celecoxib', 'DFN-15', 'DFN15', 'NSC-719627', 'NSC-758624', 'SC-58635']", 'yearOfFirstApproval': 1998, 'max_phase_for_ind': 4.0, 'mesh_heading': 'S...
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Q34.66
Q34
What are the names of the genes that are targeted by the drug Metoclopramide Hydrochloride in the treatment of gastroparesis?
In the context of gastroparesis, the drug Metoclopramide Hydrochloride targets the gene dopamine receptor D2, 5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine receptor 4.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%gastroparesis%" OR LOWER(efo_term) LIKE "%gastropares...
[{'UUID': 'DrugTargetsIndication121923_text_199704', 'drugName': 'Metoclopramide Hydrochloride', 'tradeNames_list': '[\'"clopra-""yellow"""\', \'Clopra\', \'Clopra-"Yellow"\', \'Gastrese l.a.Gastrobid continus\', \'Gastroflux\', \'Gastromax\', \'Gimoti\', \'MaxolonMaxolon sr\', \'Metoclomex\', \'Metoclopramide hydrochl...
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Q34.483
Q34
What are the names of the genes that are targeted by the drug Dextroamphetamine in the treatment of narcolepsy-cataplexy syndrome?
In the context of narcolepsy-cataplexy syndrome, the drug Dextroamphetamine targets the gene solute carrier family 6 member 2, solute carrier family 18 member A2 and solute carrier family 6 member 3.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%narcolepsy-cataplexy syndrome%" OR LOWER(efo_term) LI...
[{'UUID': 'DrugTargetsIndication121923_text_418427', 'drugName': 'Dextroamphetamine', 'tradeNames_list': "['Dexedrine', 'Dextrostat', 'Xelstrym']", 'syns_list': "['Amfetamine, (s)-', 'Amphetamine, d-', 'D-amphetamine', 'DexamfetamineDexampex', 'Dexamphetamine', 'Dexedrine', 'Dexidrine', 'DextroamphetamineDextroamphetam...
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Q34.1168
Q34
What are the names of the genes that are targeted by the drug Trametinib in the treatment of melanoma?
Trametinib has not been approved by the FDA as a treatment for melanoma, but it is currently undergoing evaluation in clinical trials for this purpose. However, the proposed gene target names are mitogen-activated protein kinase kinase 2 and mitogen-activated protein kinase kinase 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%melanoma%" OR LOWER(efo_term) LIKE "%melanoma%") AND ...
[{'UUID': 'DrugTargetsIndication121923_text_927744', 'drugName': 'Trametinib Dimethyl Sulfoxide', 'tradeNames_list': "['Mekinist']", 'syns_list': "['GSK-1120212B', 'GSK1120212B', 'Trametinib dimethyl sulfoxide']", 'yearOfFirstApproval': 2013, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Melanoma', 'efo_term': 'metastatic...
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Q34.1001
Q34
What are the names of the genes that are targeted by the drug Aclidinium Bromide in the treatment of Airway obstruction?
In the context of Airway obstruction, the drug Aclidinium Bromide targets the gene cholinergic receptor muscarinic 3.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%airway obstruction%" OR LOWER(efo_term) LIKE "%airway...
[{'UUID': 'DrugTargetsIndication121923_text_857457', 'drugName': 'Aclidinium Bromide', 'tradeNames_list': "['Eklira', 'Tudorza pressair']", 'syns_list': "['14115700', 'Aclidinium bromide', 'Genuair', 'LAS 34273LAS 34273 MICRONIZED', 'LAS W-330', 'LAS-34273', 'LAS-34273 MICRONIZEDLAS-W-330']", 'yearOfFirstApproval': 201...
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Q34.1104
Q34
What are the names of the genes that are targeted by the drug Darolutamide in the treatment of neoplasm?
In the context of neoplasm, the drug Darolutamide targets the gene androgen receptor.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%neoplasm%" OR LOWER(efo_term) LIKE "%neoplasm%") AND ...
[{'UUID': 'DrugTargetsIndication121923_text_924390', 'drugName': 'Darolutamide', 'tradeNames_list': "['Nubeqa']", 'syns_list': "['BAY 1841788', 'BAY-1841788', 'BAY1841788', 'Darolutamide', 'ODM-201Odm-201']", 'yearOfFirstApproval': 2019, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Prostatic Neoplasms', 'efo_term': 'pros...
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Q34.1735
Q34
What are the names of the genes that are targeted by the drug Vutrisiran in the treatment of polyneuropathy?
In the context of polyneuropathy, the drug Vutrisiran targets the gene transthyretin.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%polyneuropathy%" OR LOWER(efo_term) LIKE "%polyneurop...
[{'UUID': 'DrugTargetsIndication121923_text_1097671', 'drugName': 'Vutrisiran', 'tradeNames_list': "['Amvuttra']", 'syns_list': "['ALN-65492', 'ALN-TTRSC02', 'Votrisiran', 'Vutrisiran']", 'yearOfFirstApproval': 2022, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Polyneuropathies', 'efo_term': 'polyneuropathy', 'approvedSy...
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Q34.30
Q34
What are the names of the genes that are targeted by the drug Clozapine in the treatment of schizoaffective disorder?
In the context of schizoaffective disorder, the drug Clozapine targets the gene dopamine receptor D2 and 5-hydroxytryptamine receptor 2A.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%schizoaffective disorder%" OR LOWER(efo_term) LIKE "%...
[{'UUID': 'DrugTargetsIndication121923_text_157985', 'drugName': 'Clozapine', 'tradeNames_list': "['Clozapine', 'Clozaril', 'Fazaclo', 'Fazaclo odt', 'Versacloz', 'Zaponex']", 'syns_list': "['Clozapine', 'Clozapine (caraco)', 'Clozapine (clozaril)Clozapine (fazaclo)', 'Clozapine (ivax)', 'Clozapine (mylan)Clozapine (te...
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Q34.622
Q34
What are the names of the genes that are targeted by the drug Nintedanib in the treatment of idiopathic pulmonary fibrosis?
In the context of idiopathic pulmonary fibrosis, the drug Nintedanib targets the gene kinase insert domain receptor, fibroblast growth factor receptor 1, fibroblast growth factor receptor 3, fibroblast growth factor receptor 2, fms related receptor tyrosine kinase 1, fms related receptor tyrosine kinase 4, platelet der...
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%idiopathic pulmonary fibrosis%" OR LOWER(efo_term) LI...
[{'UUID': 'DrugTargetsIndication121923_text_678478', 'drugName': 'Nintedanib Esylate', 'tradeNames_list': "['Ofev']", 'syns_list': "['Nintedanib esilate', 'Nintedanib esylate', 'Nintedanib ethanesulfonate']", 'yearOfFirstApproval': 2014, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Idiopathic Pulmonary Fibrosis', 'efo_te...
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Q34.344
Q34
What are the names of the genes that are targeted by the drug Dexamethasone in the treatment of choroiditis?
In the context of choroiditis, the drug Dexamethasone targets the gene nuclear receptor subfamily 3 group C member 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%choroiditis%" OR LOWER(efo_term) LIKE "%choroiditis%"...
[{'UUID': 'DrugTargetsIndication121923_text_227800', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex...
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Q34.855
Q34
What are the names of the genes that are targeted by the drug Aspirin in the treatment of Headache?
In the context of Headache, the drug Aspirin targets the gene prostaglandin-endoperoxide synthase 2 and prostaglandin-endoperoxide synthase 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%headache%" OR LOWER(efo_term) LIKE "%headache%") AND ...
[{'UUID': 'DrugTargetsIndication121923_text_833954', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin...
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Q34.1844
Q34
What are the names of the genes that are targeted by the drug Simvastatin in the treatment of Hypercholesterolemia?
In the context of Hypercholesterolemia, the drug Simvastatin targets the gene 3-hydroxy-3-methylglutaryl-CoA reductase.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%hypercholesterolemia%" OR LOWER(efo_term) LIKE "%hype...
[{'UUID': 'DrugTargetsIndication121923_text_1104005', 'drugName': 'Simvastatin', 'tradeNames_list': "['Flolipid', 'Lacersa', 'Ranzolont', 'Simvador', 'Simvastatin', 'ZocorZocor heart-pro']", 'syns_list': "['C10AA01', 'MK-0733', 'MK-733', 'NSC-758706', 'SimvastatinSimvastatin hydroxy acid', 'Synvinolin']", 'yearOfFirstA...
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Q34.1974
Q34
What are the names of the genes that are targeted by the drug Topotecan Hydrochloride in the treatment of ovarian cancer?
In the context of ovarian cancer, the drug Topotecan Hydrochloride targets the gene DNA topoisomerase I mitochondrial.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%ovarian cancer%" OR LOWER(efo_term) LIKE "%ovarian ca...
[{'UUID': 'DrugTargetsIndication121923_text_1193578', 'drugName': 'Topotecan Hydrochloride', 'tradeNames_list': "['Hycamptin', 'Hycamtin', 'Topotecan', 'Topotecan hydrochloride']", 'syns_list': "['Evotopin', 'NSC-759263', 'Nogitecan hydrochloride', 'SK&F S-104864-ASK&F-S-104864A', 'SK-S-104864-A', 'Topotecan (as hydroc...
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Q34.1368
Q34
What are the names of the genes that are targeted by the drug Acalabrutinib Maleate in the treatment of Mantle cell lymphoma?
In the context of Mantle cell lymphoma, the drug Acalabrutinib Maleate targets the gene Bruton tyrosine kinase.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%mantle cell lymphoma%" OR LOWER(efo_term) LIKE "%mant...
[{'UUID': 'DrugTargetsIndication121923_text_1024995', 'drugName': 'Acalabrutinib Maleate', 'tradeNames_list': "['Calquence']", 'syns_list': "['Acalabrutinib maleate', 'Acalabrutinib maleate anhydrousCalquence maleate']", 'yearOfFirstApproval': 2022, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Lymphoma, Mantle-Cell', 'ef...
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Q34.1397
Q34
What are the names of the genes that are targeted by the drug Siponimod Fumarate in the treatment of relapsing-remitting multiple sclerosis?
In the context of relapsing-remitting multiple sclerosis, the drug Siponimod Fumarate targets the gene sphingosine-1-phosphate receptor 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%relapsing-remitting multiple sclerosis%" OR LOWER(efo...
[{'UUID': 'DrugTargetsIndication121923_text_1036800', 'drugName': 'Siponimod Fumarate', 'tradeNames_list': "['Mayzent']", 'syns_list': "['NVP-BAF312-AEA', 'Siponimod fumarate', 'Siponimod fumaric acidSiponimod hemifumarate', 'Siponimod hemifumaric acid']", 'yearOfFirstApproval': 2019, 'max_phase_for_ind': 4.0, 'mesh_he...
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Q34.552
Q34
What are the names of the genes that are targeted by the drug Levocetirizine Dihydrochloride in the treatment of Rhinitis, Allergic, Perennial?
In the context of Rhinitis, Allergic, Perennial, the drug Levocetirizine Dihydrochloride targets the gene histamine receptor H1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%rhinitis, allergic, perennial%" OR LOWER(efo_term) LI...
[{'UUID': 'DrugTargetsIndication121923_text_455996', 'drugName': 'Levocetirizine Dihydrochloride', 'tradeNames_list': "['Levocetirizine dihydrochloride', 'Xusal', 'Xyzal', 'Xyzal allergy 24hrXyzall']", 'syns_list': "['Cetirizine (r)-form dihydrochloride', 'Cetirizine hydrochloride (r)-Levocetirizine dihydrochloride', '...
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Q34.454
Q34
What are the names of the genes that are targeted by the drug Epinephrine in the treatment of allergic disease?
In the context of allergic disease, the drug Epinephrine targets the gene adrenoceptor alpha 1A, adrenoceptor beta 2, adrenoceptor beta 1, adrenoceptor beta 3, adrenoceptor alpha 1D, adrenoceptor alpha 1B, adrenoceptor alpha 2A, adrenoceptor alpha 2C and adrenoceptor alpha 2B.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%allergic disease%" OR LOWER(efo_term) LIKE "%allergic...
[{'UUID': 'DrugTargetsIndication121923_text_361102', 'drugName': 'Epinephrine', 'tradeNames_list': "['Adren co', 'Adrenaclick', 'Adrenalin', 'Ana-Kit', 'Ana-guard', 'AnapenAnaphylactic shock drug kit', 'Asma-vydrin', 'Asthmahaler', 'Auvi-qBronkaid mist', 'Brovon', 'Emerade', 'Epi e z pen jr', 'EpinephrineEpinephrine (c...
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Q34.636
Q34
What are the names of the genes that are targeted by the drug Axitinib in the treatment of clear cell renal carcinoma?
In the context of clear cell renal carcinoma, the drug Axitinib targets the gene kinase insert domain receptor, fms related receptor tyrosine kinase 1 and fms related receptor tyrosine kinase 4.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%clear cell renal carcinoma%" OR LOWER(efo_term) LIKE ...
[{'UUID': 'DrugTargetsIndication121923_text_689364', 'drugName': 'Axitinib', 'tradeNames_list': "['Inlyta']", 'syns_list': "['AG-013736', 'AG-13736', 'Axitinib', 'NSC-757441']", 'yearOfFirstApproval': 2012, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Carcinoma, Renal Cell', 'efo_term': 'clear cell renal carcinoma', 'app...
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Q34.233
Q34
What are the names of the genes that are targeted by the drug Beclomethasone Dipropionate in the treatment of seasonal allergic rhinitis?
In the context of seasonal allergic rhinitis, the drug Beclomethasone Dipropionate targets the gene nuclear receptor subfamily 3 group C member 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%seasonal allergic rhinitis%" OR LOWER(efo_term) LIKE ...
[{'UUID': 'DrugTargetsIndication121923_text_221043', 'drugName': 'Beclomethasone Dipropionate', 'tradeNames_list': "['Aerobec 100', 'Aerobec 50', 'Aerobec fte 250', 'Asmabec clickhalerAsmabec spacehaler', 'Beclazone 100', 'Beclazone 100 e-breatheBeclazone 200', 'Beclazone 250', 'Beclazone 250 e-breathe', 'Beclazone 50B...
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Q34.1234
Q34
What are the names of the genes that are targeted by the drug Metoprolol Succinate in the treatment of angina pectoris?
In the context of angina pectoris, the drug Metoprolol Succinate targets the gene adrenoceptor beta 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%angina pectoris%" OR LOWER(efo_term) LIKE "%angina pe...
[{'UUID': 'DrugTargetsIndication121923_text_937658', 'drugName': 'Metoprolol Succinate', 'tradeNames_list': "['Kapspargo sprinkle', 'Metoprolol succinate', 'Toprol', 'Toprol XlToprol-xl']", 'syns_list': "['H 93/26 SUCCINATE', 'Metoprolol hemisuccinate', 'Metoprolol succinateSeloken-zok', 'Selozok']", 'yearOfFirstApprov...
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Q34.1523
Q34
What are the names of the genes that are targeted by the drug Nusinersen Sodium in the treatment of spinal muscular atrophy?
In the context of spinal muscular atrophy, the drug Nusinersen Sodium targets the gene survival of motor neuron 2, centromeric.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%spinal muscular atrophy%" OR LOWER(efo_term) LIKE "%s...
[{'UUID': 'DrugTargetsIndication121923_text_1072719', 'drugName': 'Nusinersen Sodium', 'tradeNames_list': "['Spinraza']", 'syns_list': "['Nusinersen sodium']", 'yearOfFirstApproval': 2016, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Muscular Atrophy, Spinal', 'efo_term': 'spinal muscular atrophy', 'approvedSymbol': 'SMN...
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Q34.898
Q34
What are the names of the genes that are targeted by the drug Naproxen Sodium in the treatment of frozen shoulder?
In the context of frozen shoulder, the drug Naproxen Sodium targets the gene prostaglandin-endoperoxide synthase 2 and prostaglandin-endoperoxide synthase 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%frozen shoulder%" OR LOWER(efo_term) LIKE "%frozen sh...
[{'UUID': 'DrugTargetsIndication121923_text_838135', 'drugName': 'Naproxen Sodium', 'tradeNames_list': "['Aleve', 'Anaprox', 'Anaprox ds', 'Naprelan', 'Naproxen sodium', 'Synflex']", 'syns_list': "['BAY-117031', 'BAY117031', 'BAYH6689', 'Naproxen sodiumNaproxen sodium anhydrous', 'Naproxen sodium salt', 'RS-3650']", 'y...
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Q34.368
Q34
What are the names of the genes that are targeted by the drug Halobetasol Propionate in the treatment of skin disease?
In the context of skin disease, the drug Halobetasol Propionate targets the gene nuclear receptor subfamily 3 group C member 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%skin disease%" OR LOWER(efo_term) LIKE "%skin disease...
[{'UUID': 'DrugTargetsIndication121923_text_240740', 'drugName': 'Halobetasol Propionate', 'tradeNames_list': "['Bryhali', 'Halobetasol propionate', 'Lexette', 'Ultravate']", 'syns_list': "['21-chloro diflorasone', 'BMY-30056', 'CGP-14,458', 'CGP-14458Halobetasol', 'Halobetasol propionate', 'IDP-122', 'Jemdel', 'Ulobet...
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Q34.1243
Q34
What are the names of the genes that are targeted by the drug Maraviroc in the treatment of viral disease?
In the context of viral disease, the drug Maraviroc targets the gene C-C motif chemokine receptor 5.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%viral disease%" OR LOWER(efo_term) LIKE "%viral disea...
[{'UUID': 'DrugTargetsIndication121923_text_938390', 'drugName': 'Maraviroc', 'tradeNames_list': "['Celsentri', 'Selzentry']", 'syns_list': "['Maraviroc', 'Rel-Maraviroc', 'UK-427857', 'Uk-427,857']", 'yearOfFirstApproval': 2007, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Virus Diseases', 'efo_term': 'viral disease', '...
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Q34.1537
Q34
What are the names of the genes that are targeted by the drug Dronabinol in the treatment of Nausea?
In the context of Nausea, the drug Dronabinol targets the gene cannabinoid receptor 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%nausea%" OR LOWER(efo_term) LIKE "%nausea%") AND (LOW...
[{'UUID': 'DrugTargetsIndication121923_text_1073256', 'drugName': 'Dronabinol', 'tradeNames_list': "['Dronabinol', 'Marinol', 'Syndros']", 'syns_list': "['.delta.-9-tetrahydrocannabinol', '.delta.1-thc.delta.9-tetrahydrocannabinol', '.delta.9-thc', 'ABBOTT 40566ABBOTT-40566', 'Delta-9-tetrahydrocannabinol', 'Delta-9-th...
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Q34.614
Q34
What are the names of the genes that are targeted by the drug Cabozantinib S-Malate in the treatment of renal cell carcinoma?
In the context of renal cell carcinoma, the drug Cabozantinib S-Malate targets the gene kinase insert domain receptor and MET proto-oncogene, receptor tyrosine kinase.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%renal cell carcinoma%" OR LOWER(efo_term) LIKE "%rena...
[{'UUID': 'DrugTargetsIndication121923_text_669605', 'drugName': 'Cabozantinib S-Malate', 'tradeNames_list': "['Cabometyx', 'Cometriq']", 'syns_list': "['BMS-907351', 'Cabozantinib malate', 'Cabozantinib s-malate', 'XL-184XL184']", 'yearOfFirstApproval': 2012, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Carcinoma, Renal...
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Q34.1846
Q34
What are the names of the genes that are targeted by the drug Simvastatin in the treatment of myocardial infarction?
In the context of myocardial infarction, the drug Simvastatin targets the gene 3-hydroxy-3-methylglutaryl-CoA reductase.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%myocardial infarction%" OR LOWER(efo_term) LIKE "%myo...
[{'UUID': 'DrugTargetsIndication121923_text_1104006', 'drugName': 'Simvastatin', 'tradeNames_list': "['Flolipid', 'Lacersa', 'Ranzolont', 'Simvador', 'Simvastatin', 'ZocorZocor heart-pro']", 'syns_list': "['C10AA01', 'MK-0733', 'MK-733', 'NSC-758706', 'SimvastatinSimvastatin hydroxy acid', 'Synvinolin']", 'yearOfFirstA...
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Q34.122
Q34
What are the names of the genes that are targeted by the drug Desvenlafaxine in the treatment of depressive disorder?
In the context of depressive disorder, the drug Desvenlafaxine targets the gene solute carrier family 6 member 4 and solute carrier family 6 member 2.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%depressive disorder%" OR LOWER(efo_term) LIKE "%depre...
[{'UUID': 'DrugTargetsIndication121923_text_206622', 'drugName': 'Desvenlafaxine', 'tradeNames_list': "['Desvenlafaxine', 'Khedezla', 'Pristiq']", 'syns_list': "['D-veniz', 'Desvenlafaxine', 'Mdd-xr', 'Newven', 'O-desmethylvenlafaxineODV']", 'yearOfFirstApproval': 2008, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Depres...
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Q34.1334
Q34
What are the names of the genes that are targeted by the drug Maralixibat Chloride in the treatment of Alagille syndrome?
In the context of Alagille syndrome, the drug Maralixibat Chloride targets the gene solute carrier family 10 member 2.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%alagille syndrome%" OR LOWER(efo_term) LIKE "%alagill...
[{'UUID': 'DrugTargetsIndication121923_text_992697', 'drugName': 'Maralixibat Chloride', 'tradeNames_list': "['Livmarli']", 'syns_list': "['LUM-001', 'LUM001', 'Lopixibat chloride', 'Maralixibat chloride']", 'yearOfFirstApproval': 2021, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Alagille Syndrome', 'efo_term': 'Alagill...
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Q34.596
Q34
What are the names of the genes that are targeted by the drug Lamotrigine in the treatment of bipolar disorder?
In the context of bipolar disorder, the drug Lamotrigine targets the gene sodium voltage-gated channel alpha subunit 1, sodium voltage-gated channel alpha subunit 5, sodium voltage-gated channel alpha subunit 4, sodium voltage-gated channel alpha subunit 7, sodium voltage-gated channel alpha subunit 2, sodium voltage-g...
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%bipolar disorder%" OR LOWER(efo_term) LIKE "%bipolar ...
[{'UUID': 'DrugTargetsIndication121923_text_653062', 'drugName': 'Lamotrigine', 'tradeNames_list': "['Lamictal', 'Lamictal cd', 'Lamictal odt', 'Lamictal xr', 'Lamotrigine']", 'syns_list': "['BW 430C', 'BW-430C', 'Lamotrigine', 'NSC-759171']", 'yearOfFirstApproval': 1994, 'max_phase_for_ind': 4.0, 'mesh_heading': 'Bipo...
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Q34.1160
Q34
What are the names of the genes that are targeted by the drug Trametinib in the treatment of prostate cancer?
Trametinib has not been approved by the FDA as a treatment for prostate cancer, but it is currently undergoing evaluation in clinical trials for this purpose. However, the proposed gene target names are mitogen-activated protein kinase kinase 2 and mitogen-activated protein kinase kinase 1.
SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, yearOfFirstApproval, max_phase_for_ind, mesh_heading, efo_term, approvedSymbol, approvedName FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses` WHERE (LOWER(mesh_heading) LIKE "%prostate cancer%" OR LOWER(efo_term) LIKE "%prostate ...
[{'UUID': 'DrugTargetsIndication121923_text_928588', 'drugName': 'Trametinib', 'tradeNames_list': "['Mekinist']", 'syns_list': "['GSK-1120212', 'GSK1120212', 'JTP 74057', 'JTP-74057', 'TMT-212', 'TMT212Tmt212', 'Trametinib']", 'yearOfFirstApproval': -1, 'max_phase_for_ind': 2.0, 'mesh_heading': 'Prostatic Neoplasms, Ca...
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