uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
values | bio_category stringclasses 14
values |
|---|---|---|---|---|---|---|---|---|
Q49.217 | Q49 | Are there any SMR association signals with the gene RAB8B in Alzheimer's Disease? | Yes, there are 2 SNPs within RAB8B that have significant SMR association signals in Alzheimer's Disease. Each SNP is listed with the tissue having the most significant SMR value:
• rs11858666
• Whole Brain: Adjusted SMR multi-SNP P-value: 3.45e-07; HEIDI: 7.5140e-01
• rs2729793
• Whole Blood: Adjusted SMR multi... | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RAB8B' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_105698', 'topRSID': 'rs11858666', 'Disease': 'AD', 'Gene': 'RAB8B', 'p_SMR_multi': 3.453414e-07, 'p_HEIDI': 0.7513961}, {'UUID': 'NDD_SMR_genes_all_update_text_646596', 'topRSID': 'rs2729793', 'Disease': 'AD', 'Gene': 'RAB8B', 'p_SMR_multi': 4.974919e-07, 'p_HEIDI': 0.001616564}... | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1130 | Q49 | Are there any SMR association signals with the gene BCKDK in Parkinson's Disease? | Yes, there is 1 SNP within BCKDK that has a significant SMR association signal in Parkinson's Disease:
• rs4889619
• Whole Blood: Adjusted SMR multi-SNP P-value: 7.89e-08; HEIDI: 8.2320e-03
| SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'BCKDK' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1563816', 'topRSID': 'rs4889619', 'Disease': 'PD', 'Gene': 'BCKDK', 'p_SMR_multi': 7.887199e-08, 'p_HEIDI': 0.008231964}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.330 | Q49 | Are there any SMR association signals with the gene CTD-2616J11.16 in Amyotrophic Lateral Sclerosis? | No, there are no SNPs within CTD-2616J11.16 that have significant SMR association signals in Amyotrophic Lateral Sclerosis. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'CTD-2616J11.16' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.566 | Q49 | Are there any SMR association signals with the gene COMP in Parkinson's Disease? | No, there are no SNPs within COMP that have significant SMR association signals in Parkinson's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'COMP' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1112 | Q49 | Are there any SMR association signals with the gene C10orf115 in Alzheimer's Disease? | No, there are no SNPs within C10orf115 that have significant SMR association signals in Alzheimer's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'C10orf115' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.707 | Q49 | Are there any SMR association signals with the gene RP11-1319K7.1 in Lewy Body Dementia? | No, there are no SNPs within RP11-1319K7.1 that have significant SMR association signals in Lewy Body Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'RP11-1319K7.1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1979 | Q49 | Are there any SMR association signals with the gene RP11-259P20.1 in Parkinson's Disease? | No, there are no SNPs within RP11-259P20.1 that have significant SMR association signals in Parkinson's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-259P20.1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1189 | Q49 | Are there any SMR association signals with the gene FAM54B in Lewy Body Dementia? | No, there are no SNPs within FAM54B that have significant SMR association signals in Lewy Body Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'FAM54B' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.345 | Q49 | Are there any SMR association signals with the gene CTSE in Lewy Body Dementia? | No, there are no SNPs within CTSE that have significant SMR association signals in Lewy Body Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'CTSE' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.636 | Q49 | Are there any SMR association signals with the gene AC079779.5 in Amyotrophic Lateral Sclerosis? | No, there are no SNPs within AC079779.5 that have significant SMR association signals in Amyotrophic Lateral Sclerosis. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'AC079779.5' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.150 | Q49 | Are there any SMR association signals with the gene SLC25A1P5 in Amyotrophic Lateral Sclerosis? | No, there are no SNPs within SLC25A1P5 that have significant SMR association signals in Amyotrophic Lateral Sclerosis. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'SLC25A1P5' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1197 | Q49 | Are there any SMR association signals with the gene FNBP1L in Frontotemporal Dementia? | No, there are no SNPs within FNBP1L that have significant SMR association signals in Frontotemporal Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'FNBP1L' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.365 | Q49 | Are there any SMR association signals with the gene FAM102A in Alzheimer's Disease? | No, there are no SNPs within FAM102A that have significant SMR association signals in Alzheimer's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'FAM102A' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.86 | Q49 | Are there any SMR association signals with the gene DNAJC21 in Lewy Body Dementia? | No, there are no SNPs within DNAJC21 that have significant SMR association signals in Lewy Body Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'DNAJC21' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.49 | Q49 | Are there any SMR association signals with the gene AC135048.1 in Parkinson's Disease? | Yes, there is 1 SNP within AC135048.1 that has a significant SMR association signal in Parkinson's Disease:
• rs7199949
• Whole Brain: Adjusted SMR multi-SNP P-value: 3.21e-08; HEIDI: 5.0101e-04
| SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'AC135048.1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_485448', 'topRSID': 'rs7199949', 'Disease': 'PD', 'Gene': 'AC135048.1', 'p_SMR_multi': 3.211323e-08, 'p_HEIDI': 0.0005010102}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.474 | Q49 | Are there any SMR association signals with the gene HSD3B7 in Parkinson's Disease? | Yes, there are 4 SNPs within HSD3B7 that have significant SMR association signals in Parkinson's Disease. Each SNP is listed with the tissue having the most significant SMR value:
• rs13708
• Skeletal Muscle: Adjusted SMR multi-SNP P-value: 4.21e-08; HEIDI: 3.5754e-02
• rs897986
• Multi Ancestry Whole Brain: Ad... | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'HSD3B7' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1370179', 'topRSID': 'rs13708', 'Disease': 'PD', 'Gene': 'HSD3B7', 'p_SMR_multi': 4.214737e-08, 'p_HEIDI': 0.03575398}, {'UUID': 'NDD_SMR_genes_all_update_text_1435342', 'topRSID': 'rs897986', 'Disease': 'PD', 'Gene': 'HSD3B7', 'p_SMR_multi': 5.760116e-08, 'p_HEIDI': 5.797939e-0... | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.158 | Q49 | Are there any SMR association signals with the gene TAF6 in Alzheimer's Disease? | Yes, there are 2 SNPs within TAF6 that have significant SMR association signals in Alzheimer's Disease. Each SNP is listed with the tissue having the most significant SMR value:
• rs3807479
• Tibial Nerve: Adjusted SMR multi-SNP P-value: 1.84e-08; HEIDI: 5.2692e-03
• rs6960432
• Whole Blood: Adjusted SMR multi-... | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'TAF6' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1287866', 'topRSID': 'rs3807479', 'Disease': 'AD', 'Gene': 'TAF6', 'p_SMR_multi': 1.840641e-08, 'p_HEIDI': 0.005269153}, {'UUID': 'NDD_SMR_genes_all_update_text_1495793', 'topRSID': 'rs6960432', 'Disease': 'AD', 'Gene': 'TAF6', 'p_SMR_multi': 5.244342e-08, 'p_HEIDI': 4.246328e-0... | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.764 | Q49 | Are there any SMR association signals with the gene CTD-2653D5.1 in Parkinson's Disease? | No, there are no SNPs within CTD-2653D5.1 that have significant SMR association signals in Parkinson's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CTD-2653D5.1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1027 | Q49 | Are there any SMR association signals with the gene PSTPIP1 in Progressive supranuclear palsy? | No, there are no SNPs within PSTPIP1 that have significant SMR association signals in Progressive supranuclear palsy. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'PSTPIP1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1200 | Q49 | Are there any SMR association signals with the gene SEMA3C in Alzheimer's Disease? | No, there are no SNPs within SEMA3C that have significant SMR association signals in Alzheimer's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'SEMA3C' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1404 | Q49 | Are there any SMR association signals with the gene ZKSCAN3 in Alzheimer's Disease? | Yes, there is 1 SNP within ZKSCAN3 that has a significant SMR association signal in Alzheimer's Disease:
• rs213230
• Whole Blood: Adjusted SMR multi-SNP P-value: 1.75e-06; HEIDI: 1.0278e-02
| SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ZKSCAN3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1494675', 'topRSID': 'rs213230', 'Disease': 'AD', 'Gene': 'ZKSCAN3', 'p_SMR_multi': 1.752465e-06, 'p_HEIDI': 0.01027817}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1202 | Q49 | Are there any SMR association signals with the gene RP11-391J13.1 in Parkinson's Disease? | No, there are no SNPs within RP11-391J13.1 that have significant SMR association signals in Parkinson's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-391J13.1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1631 | Q49 | Are there any SMR association signals with the gene FAM101B in Alzheimer's Disease? | No, there are no SNPs within FAM101B that have significant SMR association signals in Alzheimer's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'FAM101B' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.506 | Q49 | Are there any SMR association signals with the gene ADRB3 in Lewy Body Dementia? | No, there are no SNPs within ADRB3 that have significant SMR association signals in Lewy Body Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'ADRB3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1670 | Q49 | Are there any SMR association signals with the gene CLDN6 in Alzheimer's Disease? | No, there are no SNPs within CLDN6 that have significant SMR association signals in Alzheimer's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CLDN6' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.182 | Q49 | Are there any SMR association signals with the gene ATP1A2 in Amyotrophic Lateral Sclerosis? | No, there are no SNPs within ATP1A2 that have significant SMR association signals in Amyotrophic Lateral Sclerosis. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'ATP1A2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1419 | Q49 | Are there any SMR association signals with the gene MMRN1 in Parkinson's Disease? | Yes, there are 12 SNPs within MMRN1 that have significant SMR association signals in Parkinson's Disease. Here are the top 10 SNPs, listed with the tissue having the most significant SMR value:
• rs1372525
• Whole Blood: Adjusted SMR multi-SNP P-value: 1.83e-15; HEIDI: 2.60e-20
• rs79093919
• Multi Ancestry Who... | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'MMRN1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1555944', 'topRSID': 'rs1372525', 'Disease': 'PD', 'Gene': 'MMRN1', 'p_SMR_multi': 1.827247e-15, 'p_HEIDI': 2.599436e-20}, {'UUID': 'NDD_SMR_genes_all_update_text_1430395', 'topRSID': 'rs79093919', 'Disease': 'PD', 'Gene': 'MMRN1', 'p_SMR_multi': 8.451387e-15, 'p_HEIDI': 1.29381... | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1014 | Q49 | Are there any SMR association signals with the gene SUCO in Parkinson's Disease? | No, there are no SNPs within SUCO that have significant SMR association signals in Parkinson's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'SUCO' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1978 | Q49 | Are there any SMR association signals with the gene TMEM167A in Lewy Body Dementia? | No, there are no SNPs within TMEM167A that have significant SMR association signals in Lewy Body Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'TMEM167A' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.864 | Q49 | Are there any SMR association signals with the gene OR1J1 in Parkinson's Disease? | No, there are no SNPs within OR1J1 that have significant SMR association signals in Parkinson's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'OR1J1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1620 | Q49 | Are there any SMR association signals with the gene NFYA in Alzheimer's Disease? | Yes, there are 4 SNPs within NFYA that have significant SMR association signals in Alzheimer's Disease. Each SNP is listed with the tissue having the most significant SMR value:
• rs72856298
• Whole Blood: Adjusted SMR multi-SNP P-value: 3.34e-10; HEIDI: 1.12e-10
• rs62396353
• Whole Blood: Adjusted SMR multi-S... | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'NFYA' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_622639', 'topRSID': 'rs72856298', 'Disease': 'AD', 'Gene': 'NFYA', 'p_SMR_multi': 3.336665e-10, 'p_HEIDI': 1.123977e-10}, {'UUID': 'NDD_SMR_genes_all_update_text_622641', 'topRSID': 'rs72856298', 'Disease': 'AD', 'Gene': 'NFYA', 'p_SMR_multi': 5.531627e-10, 'p_HEIDI': 7.741809e-... | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.534 | Q49 | Are there any SMR association signals with the gene AC064853.3 in Parkinson's Disease? | No, there are no SNPs within AC064853.3 that have significant SMR association signals in Parkinson's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'AC064853.3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.350 | Q49 | Are there any SMR association signals with the gene RAD54L2 in Parkinson's Disease? | No, there are no SNPs within RAD54L2 that have significant SMR association signals in Parkinson's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RAD54L2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1389 | Q49 | Are there any SMR association signals with the gene CTD-2020K17.1 in Progressive supranuclear palsy? | Yes, there is 1 SNP within CTD-2020K17.1 that has a significant SMR association signal in Progressive supranuclear palsy:
• rs1981997
• Cerebellum: Adjusted SMR multi-SNP P-value: 9.88e-09; HEIDI: 7.6771e-03
| SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'CTD-2020K17.1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1714144', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'CTD-2020K17.1', 'p_SMR_multi': 9.875865e-09, 'p_HEIDI': 0.007677051}, {'UUID': 'NDD_SMR_genes_all_update_text_1444265', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'CTD-2020K17.1', 'p_SMR_multi': 4.557684e-08, 'p... | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1961 | Q49 | Are there any SMR association signals with the gene BCKDK in Alzheimer's Disease? | Yes, there is 1 SNP within BCKDK that has a significant SMR association signal in Alzheimer's Disease:
• rs4889619
• Whole Blood: Adjusted SMR multi-SNP P-value: 7.33e-08; HEIDI: 4.0732e-01
| SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'BCKDK' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1501480', 'topRSID': 'rs4889619', 'Disease': 'AD', 'Gene': 'BCKDK', 'p_SMR_multi': 7.332338e-08, 'p_HEIDI': 0.4073159}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1301 | Q49 | Are there any SMR association signals with the gene WDR11-AS1 in Progressive supranuclear palsy? | No, there are no SNPs within WDR11-AS1 that have significant SMR association signals in Progressive supranuclear palsy. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'WDR11-AS1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1973 | Q49 | Are there any SMR association signals with the gene RP11-369E15.3 in Parkinson's Disease? | No, there are no SNPs within RP11-369E15.3 that have significant SMR association signals in Parkinson's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-369E15.3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1980 | Q49 | Are there any SMR association signals with the gene CTD-2366F13.2 in Frontotemporal Dementia? | No, there are no SNPs within CTD-2366F13.2 that have significant SMR association signals in Frontotemporal Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'CTD-2366F13.2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.608 | Q49 | Are there any SMR association signals with the gene FMNL1 in Alzheimer's Disease? | Yes, there is 1 SNP within FMNL1 that has a significant SMR association signal in Alzheimer's Disease:
• rs62063276
• Multi Ancestry Whole Brain: Adjusted SMR multi-SNP P-value: 2.21e-06; HEIDI: 6.6971e-01
| SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'FMNL1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1396742', 'topRSID': 'rs62063276', 'Disease': 'AD', 'Gene': 'FMNL1', 'p_SMR_multi': 2.210046e-06, 'p_HEIDI': 0.6697149}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1050 | Q49 | Are there any SMR association signals with the gene DNASE2 in Lewy Body Dementia? | No, there are no SNPs within DNASE2 that have significant SMR association signals in Lewy Body Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'DNASE2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.246 | Q49 | Are there any SMR association signals with the gene RP11-120K18.3 in Alzheimer's Disease? | Yes, there is 1 SNP within RP11-120K18.3 that has a significant SMR association signal in Alzheimer's Disease:
• rs11574631
• Whole Blood: Adjusted SMR multi-SNP P-value: 9.87e-07; HEIDI: 1.0393e-03
| SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-120K18.3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1501485', 'topRSID': 'rs11574631', 'Disease': 'AD', 'Gene': 'RP11-120K18.3', 'p_SMR_multi': 9.866759e-07, 'p_HEIDI': 0.001039313}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1681 | Q49 | Are there any SMR association signals with the gene MYL5 in Alzheimer's Disease? | No, there are no SNPs within MYL5 that have significant SMR association signals in Alzheimer's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'MYL5' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1799 | Q49 | Are there any SMR association signals with the gene RP11-331F9.3 in Frontotemporal Dementia? | No, there are no SNPs within RP11-331F9.3 that have significant SMR association signals in Frontotemporal Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'RP11-331F9.3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1717 | Q49 | Are there any SMR association signals with the gene C19orf6 in Alzheimer's Disease? | Yes, there are 2 SNPs within C19orf6 that have significant SMR association signals in Alzheimer's Disease. Each SNP is listed with the tissue having the most significant SMR value:
• rs4807395
• Whole Blood: Adjusted SMR multi-SNP P-value: 1.49e-06; HEIDI: 3.9088e-04
• rs7251792
• Whole Blood: Adjusted SMR mult... | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'C19orf6' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_634274', 'topRSID': 'rs4807395', 'Disease': 'AD', 'Gene': 'C19orf6', 'p_SMR_multi': 1.492903e-06, 'p_HEIDI': 0.0003908802}, {'UUID': 'NDD_SMR_genes_all_update_text_634273', 'topRSID': 'rs7251792', 'Disease': 'AD', 'Gene': 'C19orf6', 'p_SMR_multi': 1.597138e-06, 'p_HEIDI': 1.7719... | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.316 | Q49 | Are there any SMR association signals with the gene ETV5 in Progressive supranuclear palsy? | No, there are no SNPs within ETV5 that have significant SMR association signals in Progressive supranuclear palsy. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'ETV5' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.441 | Q49 | Are there any SMR association signals with the gene HMGN1 in Parkinson's Disease? | No, there are no SNPs within HMGN1 that have significant SMR association signals in Parkinson's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'HMGN1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1899 | Q49 | Are there any SMR association signals with the gene TMEM127 in Parkinson's Disease? | No, there are no SNPs within TMEM127 that have significant SMR association signals in Parkinson's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'TMEM127' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1637 | Q49 | Are there any SMR association signals with the gene CPLX1 in Alzheimer's Disease? | Yes, there is 1 SNP within CPLX1 that has a significant SMR association signal in Alzheimer's Disease:
• rs6848474
• Whole Blood: Adjusted SMR multi-SNP P-value: 7.32e-07; HEIDI: 2.0401e-01
| SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CPLX1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_657229', 'topRSID': 'rs6848474', 'Disease': 'AD', 'Gene': 'CPLX1', 'p_SMR_multi': 7.32026e-07, 'p_HEIDI': 0.2040095}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.312 | Q49 | Are there any SMR association signals with the gene LRP3 in Progressive supranuclear palsy? | No, there are no SNPs within LRP3 that have significant SMR association signals in Progressive supranuclear palsy. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'LRP3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.436 | Q49 | Are there any SMR association signals with the gene C7orf61 in Alzheimer's Disease? | Yes, there is 1 SNP within C7orf61 that has a significant SMR association signal in Alzheimer's Disease:
• rs7787620
• Whole Blood: Adjusted SMR multi-SNP P-value: 3.81e-08; HEIDI: 5.63e-07
| SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'C7orf61' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1495811', 'topRSID': 'rs7787620', 'Disease': 'AD', 'Gene': 'C7orf61', 'p_SMR_multi': 3.813436e-08, 'p_HEIDI': 5.630473e-07}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.667 | Q49 | Are there any SMR association signals with the gene HS3ST1 in Alzheimer's Disease? | Yes, there are 2 SNPs within HS3ST1 that have significant SMR association signals in Alzheimer's Disease. Each SNP is listed with the tissue having the most significant SMR value:
• rs2904297
• Whole Blood: Adjusted SMR multi-SNP P-value: 6.83e-08; HEIDI: 2.4942e-01
• rs4635810
• Whole Blood: Adjusted SMR multi... | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'HS3ST1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_658578', 'topRSID': 'rs2904297', 'Disease': 'AD', 'Gene': 'HS3ST1', 'p_SMR_multi': 6.832539e-08, 'p_HEIDI': 0.2494245}, {'UUID': 'NDD_SMR_genes_all_update_text_658581', 'topRSID': 'rs4635810', 'Disease': 'AD', 'Gene': 'HS3ST1', 'p_SMR_multi': 9.792288e-08, 'p_HEIDI': 0.48141}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.376 | Q49 | Are there any SMR association signals with the gene RP11-248J18.3 in Amyotrophic Lateral Sclerosis? | No, there are no SNPs within RP11-248J18.3 that have significant SMR association signals in Amyotrophic Lateral Sclerosis. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-248J18.3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.572 | Q49 | Are there any SMR association signals with the gene ATP8B3 in Alzheimer's Disease? | Yes, there is 1 SNP within ATP8B3 that has a significant SMR association signal in Alzheimer's Disease:
• rs7250872
• Whole Blood: Adjusted SMR multi-SNP P-value: 9.57e-07; HEIDI: 5.0227e-03
| SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ATP8B3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1503153', 'topRSID': 'rs7250872', 'Disease': 'AD', 'Gene': 'ATP8B3', 'p_SMR_multi': 9.567693e-07, 'p_HEIDI': 0.005022678}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1226 | Q49 | Are there any SMR association signals with the gene HIST1H2BC in Parkinson's Disease? | No, there are no SNPs within HIST1H2BC that have significant SMR association signals in Parkinson's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'HIST1H2BC' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.184 | Q49 | Are there any SMR association signals with the gene MED18 in Alzheimer's Disease? | No, there are no SNPs within MED18 that have significant SMR association signals in Alzheimer's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'MED18' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1115 | Q49 | Are there any SMR association signals with the gene RP11-148O21.6 in Amyotrophic Lateral Sclerosis? | No, there are no SNPs within RP11-148O21.6 that have significant SMR association signals in Amyotrophic Lateral Sclerosis. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-148O21.6' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.628 | Q49 | Are there any SMR association signals with the gene PAPL in Parkinson's Disease? | No, there are no SNPs within PAPL that have significant SMR association signals in Parkinson's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'PAPL' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1910 | Q49 | Are there any SMR association signals with the gene HCN1 in Progressive supranuclear palsy? | No, there are no SNPs within HCN1 that have significant SMR association signals in Progressive supranuclear palsy. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'HCN1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1192 | Q49 | Are there any SMR association signals with the gene RP11-1415C14.2 in Frontotemporal Dementia? | No, there are no SNPs within RP11-1415C14.2 that have significant SMR association signals in Frontotemporal Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'RP11-1415C14.2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.940 | Q49 | Are there any SMR association signals with the gene RNU1-22P in Parkinson's Disease? | No, there are no SNPs within RNU1-22P that have significant SMR association signals in Parkinson's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RNU1-22P' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1774 | Q49 | Are there any SMR association signals with the gene PDZK1IP1 in Alzheimer's Disease? | No, there are no SNPs within PDZK1IP1 that have significant SMR association signals in Alzheimer's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'PDZK1IP1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1842 | Q49 | Are there any SMR association signals with the gene RP11-707A18.1 in Lewy Body Dementia? | No, there are no SNPs within RP11-707A18.1 that have significant SMR association signals in Lewy Body Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'RP11-707A18.1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1331 | Q49 | Are there any SMR association signals with the gene CRHR1-IT1 in Parkinson's Disease? | Yes, there are 18 SNPs within CRHR1-IT1 that have significant SMR association signals in Parkinson's Disease. Here are the top 10 SNPs, listed with the tissue having the most significant SMR value:
• rs2696532
• Whole Blood: Adjusted SMR multi-SNP P-value: 6.78e-15; HEIDI: -1.00e+04
• rs62055888
• Skeletal Musc... | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CRHR1-IT1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1679564', 'topRSID': 'rs2696532', 'Disease': 'PD', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 6.780794e-15, 'p_HEIDI': -9999.0}, {'UUID': 'NDD_SMR_genes_all_update_text_1370542', 'topRSID': 'rs62055888', 'Disease': 'PD', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 7.950759e-15, 'p_HEIDI': -999... | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.300 | Q49 | Are there any SMR association signals with the gene TMPRSS11F in Frontotemporal Dementia? | No, there are no SNPs within TMPRSS11F that have significant SMR association signals in Frontotemporal Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'TMPRSS11F' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1619 | Q49 | Are there any SMR association signals with the gene RP11-521O16.2 in Alzheimer's Disease? | Yes, there are 2 SNPs within RP11-521O16.2 that have significant SMR association signals in Alzheimer's Disease. Each SNP is listed with the tissue having the most significant SMR value:
• rs77279236
• Prefrontal Cortex: Adjusted SMR multi-SNP P-value: 7.65e-07; HEIDI: 2.3597e-01
• rs2404175
• Whole Brain: Adju... | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-521O16.2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1196032', 'topRSID': 'rs77279236', 'Disease': 'AD', 'Gene': 'RP11-521O16.2', 'p_SMR_multi': 7.651473e-07, 'p_HEIDI': 0.2359738}, {'UUID': 'NDD_SMR_genes_all_update_text_46329', 'topRSID': 'rs2404175', 'Disease': 'AD', 'Gene': 'RP11-521O16.2', 'p_SMR_multi': 2.626947e-06, 'p_HEID... | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.467 | Q49 | Are there any SMR association signals with the gene LRRC37A4P in Progressive supranuclear palsy? | Yes, there are 3 SNPs within LRRC37A4P that have significant SMR association signals in Progressive supranuclear palsy. Each SNP is listed with the tissue having the most significant SMR value:
• rs11012
• Multi Ancestry Whole Brain: Adjusted SMR multi-SNP P-value: 4.48e-39; HEIDI: 4.01e-41
• rs12373139
• Whole... | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'LRRC37A4P' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1444269', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 4.478326e-39, 'p_HEIDI': 4.006733e-41}, {'UUID': 'NDD_SMR_genes_all_update_text_1684928', 'topRSID': 'rs12373139', 'Disease': 'PSP', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 4.923862e-35, 'p_HEIDI':... | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1302 | Q49 | Are there any SMR association signals with the gene TMEM205 in Amyotrophic Lateral Sclerosis? | No, there are no SNPs within TMEM205 that have significant SMR association signals in Amyotrophic Lateral Sclerosis. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'TMEM205' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1250 | Q49 | Are there any SMR association signals with the gene MAPT-AS1 in Parkinson's Disease? | Yes, there are 16 SNPs within MAPT-AS1 that have significant SMR association signals in Parkinson's Disease. Here are the top 10 SNPs, listed with the tissue having the most significant SMR value:
• rs56280951
• Whole Brain: Adjusted SMR multi-SNP P-value: 3.97e-15; HEIDI: 1.1501e-03
• rs78026984
• Whole Blood:... | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'MAPT-AS1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491096', 'topRSID': 'rs56280951', 'Disease': 'PD', 'Gene': 'MAPT-AS1', 'p_SMR_multi': 3.97087e-15, 'p_HEIDI': 0.001150121}, {'UUID': 'NDD_SMR_genes_all_update_text_948871', 'topRSID': 'rs78026984', 'Disease': 'PD', 'Gene': 'MAPT-AS1', 'p_SMR_multi': 1.185713e-13, 'p_HEIDI': 1.05... | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.383 | Q49 | Are there any SMR association signals with the gene FAM217A in Progressive supranuclear palsy? | No, there are no SNPs within FAM217A that have significant SMR association signals in Progressive supranuclear palsy. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'FAM217A' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1768 | Q49 | Are there any SMR association signals with the gene NSFP1 in Alzheimer's Disease? | Yes, there is 1 SNP within NSFP1 that has a significant SMR association signal in Alzheimer's Disease:
• rs17698176
• Whole Blood: Adjusted SMR multi-SNP P-value: 1.68e-06; HEIDI: 6.51e-05
| SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'NSFP1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1502455', 'topRSID': 'rs17698176', 'Disease': 'AD', 'Gene': 'NSFP1', 'p_SMR_multi': 1.680843e-06, 'p_HEIDI': 6.510929e-05}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.108 | Q49 | Are there any SMR association signals with the gene CLDN4 in Lewy Body Dementia? | No, there are no SNPs within CLDN4 that have significant SMR association signals in Lewy Body Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'CLDN4' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.129 | Q49 | Are there any SMR association signals with the gene RP5-1109J22.2 in Alzheimer's Disease? | No, there are no SNPs within RP5-1109J22.2 that have significant SMR association signals in Alzheimer's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP5-1109J22.2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1131 | Q49 | Are there any SMR association signals with the gene CCPG1 in Frontotemporal Dementia? | No, there are no SNPs within CCPG1 that have significant SMR association signals in Frontotemporal Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'CCPG1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.872 | Q49 | Are there any SMR association signals with the gene ZNF66 in Lewy Body Dementia? | No, there are no SNPs within ZNF66 that have significant SMR association signals in Lewy Body Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'ZNF66' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.360 | Q49 | Are there any SMR association signals with the gene CTA-250D10.23 in Progressive supranuclear palsy? | No, there are no SNPs within CTA-250D10.23 that have significant SMR association signals in Progressive supranuclear palsy. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'CTA-250D10.23' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1617 | Q49 | Are there any SMR association signals with the gene CLU in Alzheimer's Disease? | Yes, there are 8 SNPs within CLU that have significant SMR association signals in Alzheimer's Disease. Each SNP is listed with the tissue having the most significant SMR value:
• rs7982
• Whole Brain: Adjusted SMR multi-SNP P-value: 2.50e-10; HEIDI: 6.85e-05
• rs1532278
• Whole Brain: Adjusted SMR multi-SNP P-v... | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CLU' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_78262', 'topRSID': 'rs7982', 'Disease': 'AD', 'Gene': 'CLU', 'p_SMR_multi': 2.501744e-10, 'p_HEIDI': 6.84878e-05}, {'UUID': 'NDD_SMR_genes_all_update_text_78261', 'topRSID': 'rs1532278', 'Disease': 'AD', 'Gene': 'CLU', 'p_SMR_multi': 3.617787e-09, 'p_HEIDI': 1.043984e-05}, {'UUI... | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.689 | Q49 | Are there any SMR association signals with the gene C2orf51 in Lewy Body Dementia? | No, there are no SNPs within C2orf51 that have significant SMR association signals in Lewy Body Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'C2orf51' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1787 | Q49 | Are there any SMR association signals with the gene XKR7 in Progressive supranuclear palsy? | No, there are no SNPs within XKR7 that have significant SMR association signals in Progressive supranuclear palsy. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'XKR7' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1467 | Q49 | Are there any SMR association signals with the gene CTD-2303H24.2 in Amyotrophic Lateral Sclerosis? | No, there are no SNPs within CTD-2303H24.2 that have significant SMR association signals in Amyotrophic Lateral Sclerosis. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'CTD-2303H24.2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.212 | Q49 | Are there any SMR association signals with the gene DFNB59 in Frontotemporal Dementia? | No, there are no SNPs within DFNB59 that have significant SMR association signals in Frontotemporal Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'DFNB59' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.880 | Q49 | Are there any SMR association signals with the gene C8orf48 in Alzheimer's Disease? | No, there are no SNPs within C8orf48 that have significant SMR association signals in Alzheimer's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'C8orf48' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.143 | Q49 | Are there any SMR association signals with the gene RP13-39P12.3 in Alzheimer's Disease? | No, there are no SNPs within RP13-39P12.3 that have significant SMR association signals in Alzheimer's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP13-39P12.3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1439 | Q49 | Are there any SMR association signals with the gene RP11-27K13.3 in Lewy Body Dementia? | No, there are no SNPs within RP11-27K13.3 that have significant SMR association signals in Lewy Body Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'RP11-27K13.3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1341 | Q49 | Are there any SMR association signals with the gene RHOJ in Alzheimer's Disease? | No, there are no SNPs within RHOJ that have significant SMR association signals in Alzheimer's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RHOJ' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1786 | Q49 | Are there any SMR association signals with the gene CCNL1 in Amyotrophic Lateral Sclerosis? | No, there are no SNPs within CCNL1 that have significant SMR association signals in Amyotrophic Lateral Sclerosis. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'CCNL1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1575 | Q49 | Are there any SMR association signals with the gene ACVR1C in Lewy Body Dementia? | No, there are no SNPs within ACVR1C that have significant SMR association signals in Lewy Body Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'ACVR1C' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1865 | Q49 | Are there any SMR association signals with the gene RP11-332H18.4 in Frontotemporal Dementia? | No, there are no SNPs within RP11-332H18.4 that have significant SMR association signals in Frontotemporal Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'RP11-332H18.4' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1749 | Q49 | Are there any SMR association signals with the gene SIGMAR1 in Frontotemporal Dementia? | No, there are no SNPs within SIGMAR1 that have significant SMR association signals in Frontotemporal Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'SIGMAR1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.718 | Q49 | Are there any SMR association signals with the gene HBE1 in Alzheimer's Disease? | No, there are no SNPs within HBE1 that have significant SMR association signals in Alzheimer's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'HBE1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1936 | Q49 | Are there any SMR association signals with the gene KRTAP2-2 in Alzheimer's Disease? | No, there are no SNPs within KRTAP2-2 that have significant SMR association signals in Alzheimer's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'KRTAP2-2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.852 | Q49 | Are there any SMR association signals with the gene CBX3 in Amyotrophic Lateral Sclerosis? | No, there are no SNPs within CBX3 that have significant SMR association signals in Amyotrophic Lateral Sclerosis. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'CBX3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1938 | Q49 | Are there any SMR association signals with the gene CACNB2 in Lewy Body Dementia? | No, there are no SNPs within CACNB2 that have significant SMR association signals in Lewy Body Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'CACNB2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.11 | Q49 | Are there any SMR association signals with the gene SPPL2C in Alzheimer's Disease? | Yes, there are 2 SNPs within SPPL2C that have significant SMR association signals in Alzheimer's Disease. Each SNP is listed with the tissue having the most significant SMR value:
• rs2532233
• Cerebellum: Adjusted SMR multi-SNP P-value: 2.37e-06; HEIDI: -1.00e+04
• rs17573607
• Cerebellum: Adjusted SMR multi-S... | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'SPPL2C' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_2656', 'topRSID': 'rs2532233', 'Disease': 'AD', 'Gene': 'SPPL2C', 'p_SMR_multi': 2.367296e-06, 'p_HEIDI': -9999.0}, {'UUID': 'NDD_SMR_genes_all_update_text_1690044', 'topRSID': 'rs17573607', 'Disease': 'AD', 'Gene': 'SPPL2C', 'p_SMR_multi': 2.714257e-06, 'p_HEIDI': 0.9201365}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1695 | Q49 | Are there any SMR association signals with the gene PDE6D in Frontotemporal Dementia? | No, there are no SNPs within PDE6D that have significant SMR association signals in Frontotemporal Dementia. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'PDE6D' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1124 | Q49 | Are there any SMR association signals with the gene C10orf118 in Alzheimer's Disease? | No, there are no SNPs within C10orf118 that have significant SMR association signals in Alzheimer's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'C10orf118' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.286 | Q49 | Are there any SMR association signals with the gene LRRC37A in Alzheimer's Disease? | Yes, there are 6 SNPs within LRRC37A that have significant SMR association signals in Alzheimer's Disease. Each SNP is listed with the tissue having the most significant SMR value:
• rs2668632
• Prefrontal Cortex: Adjusted SMR multi-SNP P-value: 1.23e-08; HEIDI: 4.0459e-03
• rs383241
• Multi Ancestry Whole Brai... | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'LRRC37A' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1203016', 'topRSID': 'rs2668632', 'Disease': 'AD', 'Gene': 'LRRC37A', 'p_SMR_multi': 1.228585e-08, 'p_HEIDI': 0.004045895}, {'UUID': 'NDD_SMR_genes_all_update_text_1396751', 'topRSID': 'rs383241', 'Disease': 'AD', 'Gene': 'LRRC37A', 'p_SMR_multi': 6.752554e-08, 'p_HEIDI': -9999.... | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.817 | Q49 | Are there any SMR association signals with the gene ATP5G1P7 in Alzheimer's Disease? | No, there are no SNPs within ATP5G1P7 that have significant SMR association signals in Alzheimer's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ATP5G1P7' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.1092 | Q49 | Are there any SMR association signals with the gene EFNA3 in Parkinson's Disease? | Yes, there is 1 SNP within EFNA3 that has a significant SMR association signal in Parkinson's Disease:
• rs3765087
• Whole Brain: Adjusted SMR multi-SNP P-value: 1.13e-06; HEIDI: 1.4472e-01
| SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'EFNA3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_415496', 'topRSID': 'rs3765087', 'Disease': 'PD', 'Gene': 'EFNA3', 'p_SMR_multi': 1.128061e-06, 'p_HEIDI': 0.1447173}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.295 | Q49 | Are there any SMR association signals with the gene CCDC180 in Progressive supranuclear palsy? | No, there are no SNPs within CCDC180 that have significant SMR association signals in Progressive supranuclear palsy. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'CCDC180' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q49.761 | Q49 | Are there any SMR association signals with the gene IFIT2 in Alzheimer's Disease? | No, there are no SNPs within IFIT2 that have significant SMR association signals in Alzheimer's Disease. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'IFIT2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
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