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| ABCA1[[:space:]]Agonist[[:space:]]Reverses[[:space:]]the[[:space:]]ApoE4-Driven[[:space:]]Cognitive[[:space:]]and[[:space:]]Brain[[:space:]]Pathologies[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| APOE[[:space:]]Lipoprotein[[:space:]]Particles-[[:space:]]Pathophysiology,[[:space:]]Therapy,[[:space:]]and[[:space:]]the[[:space:]]Crosstalk[[:space:]]in[[:space:]]Alzheimer’s[[:space:]]Disease[[:space:]]and[[:space:]]Cardiovascular[[:space:]]Disease.pdf filter=lfs diff=lfs merge=lfs -text |
| Abca1[[:space:]]deficiency[[:space:]]affects[[:space:]]Alzheimer's[[:space:]]disease-like[[:space:]]phenotype[[:space:]]in[[:space:]]human[[:space:]]ApoE4[[:space:]]but[[:space:]]not[[:space:]]in[[:space:]]ApoE3-targeted[[:space:]]replacement[[:space:]]mice[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| ApoE4[[:space:]]Alters[[:space:]]ABCA1[[:space:]]Membrane[[:space:]]Trafficking[[:space:]]in[[:space:]]Astrocytes[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| ApoE4[[:space:]]Alters[[:space:]]ABCA1[[:space:]]Membrane[[:space:]]Trafficking[[:space:]]in[[:space:]]Astrocytes.pdf filter=lfs diff=lfs merge=lfs -text |
| Apolipoprotein[[:space:]]E[[:space:]]in[[:space:]]Alzheimer’s[[:space:]]disease-[[:space:]]molecular[[:space:]]insights[[:space:]]and[[:space:]]therapeutic[[:space:]]opportunities.pdf filter=lfs diff=lfs merge=lfs -text |
| Apolipoprotein[[:space:]]E4[[:space:]]Is[[:space:]]Deficient[[:space:]]in[[:space:]]Inducing[[:space:]]Macrophage[[:space:]]ABCA1[[:space:]]Expression[[:space:]]and[[:space:]]Stimulating[[:space:]]the[[:space:]]Sp1[[:space:]]Signaling[[:space:]]Pathway.pdf filter=lfs diff=lfs merge=lfs -text |
| Cellular[[:space:]]senescence[[:space:]]induced[[:space:]]by[[:space:]]cholesterol[[:space:]]accumulation[[:space:]]is[[:space:]]mediated[[:space:]]by[[:space:]]lysosomal[[:space:]]ABCA1[[:space:]]in[[:space:]]APOE4[[:space:]]and[[:space:]]AD.pdf filter=lfs diff=lfs merge=lfs -text |
| Cholesterol[[:space:]]accumulation[[:space:]]promotes[[:space:]]ABCA1[[:space:]]degradation[[:space:]]in[[:space:]]astrocytes[[:space:]]via[[:space:]]Caveolin-1[[:space:]]mediated[[:space:]]endocytosis[[:space:]]in[[:space:]]ApoE4.pdf filter=lfs diff=lfs merge=lfs -text |
| Differential[[:space:]]Effects[[:space:]]of[[:space:]]apoE4[[:space:]]and[[:space:]]Activation[[:space:]]of[[:space:]]ABCA1[[:space:]]on[[:space:]]Brain[[:space:]]and[[:space:]]Plasma[[:space:]]Lipoproteins.pdf filter=lfs diff=lfs merge=lfs -text |
| Liver[[:space:]]X[[:space:]]receptor[[:space:]]agonist[[:space:]]treatment[[:space:]]significantly[[:space:]]affects[[:space:]]phenotype[[:space:]]and[[:space:]]transcriptome[[:space:]]of[[:space:]]APOE3[[:space:]]and[[:space:]]APOE4[[:space:]]Abca1[[:space:]]haplo-deficient[[:space:]]mice.pdf filter=lfs diff=lfs merge=lfs -text |
| Molecular[[:space:]]interactions[[:space:]]between[[:space:]]apoE[[:space:]]and[[:space:]]ABCA1-[[:space:]]impact[[:space:]]on[[:space:]]apoE[[:space:]]lipidation[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| The[[:space:]]role[[:space:]]of[[:space:]]ATP-binding[[:space:]]cassette[[:space:]]subfamily[[:space:]]A[[:space:]]in[[:space:]]the[[:space:]]etiology[[:space:]]of[[:space:]]Alzheimer’s[[:space:]]disease.pdf filter=lfs diff=lfs merge=lfs -text |
| ABCA1[[:space:]]activity[[:space:]]is[[:space:]]associated[[:space:]]with[[:space:]]reduced[[:space:]]Alzheimer’s[[:space:]]Disease[[:space:]]risk[[:space:]]in[[:space:]]APOE[[:space:]]ε4[[:space:]]non-carriers[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| ABCA1-[[:space:]]and[[:space:]]ABCG1-mediated[[:space:]]cholesterol[[:space:]]efflux[[:space:]]capacity[[:space:]]of[[:space:]]cerebrospinal[[:space:]]fluid[[:space:]]is[[:space:]]impaired[[:space:]]in[[:space:]]Alzheimer's[[:space:]]disease[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| APOE4[[:space:]]disrupts[[:space:]]intracellular[[:space:]]lipid[[:space:]]homeostasis[[:space:]]in[[:space:]]human[[:space:]]iPSC-derived[[:space:]]glia[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| APOE4[[:space:]]homozygosity[[:space:]]represents[[:space:]]a[[:space:]]distinct[[:space:]]genetic[[:space:]]form[[:space:]]of[[:space:]]Alzheimer’s[[:space:]]disease.pdf filter=lfs diff=lfs merge=lfs -text |
| APOE4:4[[:space:]]is[[:space:]]linked[[:space:]]to[[:space:]]damaging[[:space:]]lipid[[:space:]]droplets[[:space:]]in[[:space:]]Alzheimer’s[[:space:]]microglia[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| Abca1[[:space:]]Deficiency[[:space:]]Affects[[:space:]]Alzheimer's[[:space:]]Disease-Like[[:space:]]Phenotype[[:space:]]in[[:space:]]Human[[:space:]]ApoE4[[:space:]]But[[:space:]]Not[[:space:]]in[[:space:]]ApoE3-Targeted[[:space:]]Replacement[[:space:]]Mice[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| ApoE[[:space:]]influences[[:space:]]amyloid-β[[:space:]](Aβ)[[:space:]]clearance[[:space:]]despite[[:space:]]minimal[[:space:]]apoE:Aβ[[:space:]]association[[:space:]]in[[:space:]]physiological[[:space:]]conditions[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| ApoE4[[:space:]]Accelerates[[:space:]]Early[[:space:]]Seeding[[:space:]]of[[:space:]]Amyloid[[:space:]]Pathology[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| Apolipoprotein[[:space:]]E[[:space:]]Genotype[[:space:]]Affects[[:space:]]Size[[:space:]]of[[:space:]]ApoE[[:space:]]Complexes[[:space:]]in[[:space:]]Cerebrospinal[[:space:]]Fluid[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| Apolipoprotein[[:space:]]E[[:space:]]aggregation[[:space:]]in[[:space:]]microglia,[[:space:]]seeds[[:space:]]β-amyloidosis[[:space:]]in[[:space:]]Alzheimer’s[[:space:]]disease[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| Apolipoprotein[[:space:]]E[[:space:]]ε4[[:space:]]and[[:space:]]age[[:space:]]effects[[:space:]]on[[:space:]]florbetapir[[:space:]]positron[[:space:]]emission[[:space:]]tomography[[:space:]]in[[:space:]]healthy[[:space:]]aging[[:space:]]and[[:space:]]Alzheimer[[:space:]]disease[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| Apolipoprotein[[:space:]]E4[[:space:]]in[[:space:]]Alzheimer’s[[:space:]]Disease-[[:space:]]Role[[:space:]]in[[:space:]]Pathology,[[:space:]]Lipid[[:space:]]Metabolism,[[:space:]]and[[:space:]]Drug[[:space:]]Treatment[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| Apolipoprotein[[:space:]]E–dependent[[:space:]]accumulation[[:space:]]of[[:space:]]Alzheimer[[:space:]]disease–related[[:space:]]lesions[[:space:]]begins[[:space:]]in[[:space:]]middle[[:space:]]age†[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| Cellular[[:space:]]senescence[[:space:]]induced[[:space:]]by[[:space:]]cholesterol[[:space:]]accumulation[[:space:]]is[[:space:]]mediated[[:space:]]by[[:space:]]lysosomal[[:space:]]ABCA1[[:space:]]in[[:space:]]APOE4[[:space:]]and[[:space:]]AD[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| Central[[:space:]]Nervous[[:space:]]System[[:space:]]Lipoproteins-[[:space:]]ApoE[[:space:]]and[[:space:]]Regulation[[:space:]]of[[:space:]]Cholesterol[[:space:]]Metabolism[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| Cholesterol[[:space:]]and[[:space:]]matrisome[[:space:]]pathways[[:space:]]dysregulated[[:space:]]in[[:space:]]astrocytes[[:space:]]and[[:space:]]microglia[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| Fibrillar[[:space:]]amyloid-β[[:space:]]burden[[:space:]]in[[:space:]]cognitively[[:space:]]normal[[:space:]]people[[:space:]]at[[:space:]]3[[:space:]]levels[[:space:]]of[[:space:]]genetic[[:space:]]risk[[:space:]]for[[:space:]]Alzheimer's[[:space:]]disease[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| Human[[:space:]]apoE[[:space:]]Isoforms[[:space:]]Differentially[[:space:]]Regulate[[:space:]]Brain[[:space:]]Amyloid-β[[:space:]]Peptide[[:space:]]Clearance[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| Increased[[:space:]]amyloid[[:space:]]beta-peptide[[:space:]]deposition[[:space:]]in[[:space:]]cerebral[[:space:]]cortex[[:space:]]as[[:space:]]a[[:space:]]consequence[[:space:]]of[[:space:]]apolipoprotein[[:space:]]E[[:space:]]genotype[[:space:]]in[[:space:]]late-onset[[:space:]]Alzheimer[[:space:]]disease.[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| Lipidome[[:space:]]and[[:space:]]Proteome[[:space:]]of[[:space:]]Astrocyte[[:space:]]and[[:space:]]Microglia[[:space:]]ApoE[[:space:]]Lipoprotein[[:space:]]Reveal[[:space:]]Differences[[:space:]]Based[[:space:]]on[[:space:]]Cell[[:space:]]Type[[:space:]]and[[:space:]]ApoE[[:space:]]Isoform[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| Omega-3[[:space:]]fatty[[:space:]]acids,[[:space:]]lipids,[[:space:]]and[[:space:]]apoE[[:space:]]lipidation[[:space:]]in[[:space:]]Alzheimer's[[:space:]]disease-[[:space:]]a[[:space:]]rationale[[:space:]]for[[:space:]]multi-nutrient[[:space:]]dementia[[:space:]]prevention-[[:space:]]Thematic[[:space:]]Review[[:space:]]Series-[[:space:]]ApoE[[:space:]]and[[:space:]]Lipid[[:space:]]Homeostasis[[:space:]]in[[:space:]]Alzheimer's[[:space:]]Disease[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
| Overexpression[[:space:]]of[[:space:]]ABCA1[[:space:]]reduces[[:space:]]amyloid[[:space:]]deposition[[:space:]]in[[:space:]]the[[:space:]]PDAPP[[:space:]]mouse[[:space:]]model[[:space:]]of[[:space:]]Alzheimer[[:space:]]disease[[:space:]].pdf filter=lfs diff=lfs merge=lfs -text |
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