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However, the general and mental condition was relatively better. | [
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] | A 35-year-old mentally ill man was transferred from a local psychiatric hospital after attempted suicide by fire 3 days before admission. He acquired full-and partial-thickness injury in approximately 38% of his TBSA, including face and neck (5%), both upper extremities (8%), right thigh (4%), left thigh and leg (3%), ... | EN100658 |
The patient was discharged from the hospital. | [
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A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. | [
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There was no vomiting or weight loss. | [
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... | A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. There was no vomiting or weight loss. Bowel movements were normal. Clinical examination at the time was unrevealing. An abdominal ultrasound examination was reported as normal. The patient’s insist... | EN100415 |
Bowel movements were normal. | [
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... | A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. There was no vomiting or weight loss. Bowel movements were normal. Clinical examination at the time was unrevealing. An abdominal ultrasound examination was reported as normal. The patient’s insist... | EN100415 |
Clinical examination at the time was unrevealing. | [
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An abdominal ultrasound examination was reported as normal. | [
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The patient’s insistence on full investigation of the persistent epigastric pain led to a computed tomographic examination and discovery of a pancreatic tumour subsequent to which she was referred to our institution. | [
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... | A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. There was no vomiting or weight loss. Bowel movements were normal. Clinical examination at the time was unrevealing. An abdominal ultrasound examination was reported as normal. The patient’s insist... | EN100415 |
The CT scan showed a large tumour (6cm in largest diameter) in the body and tail of pancreas with no evidence of metastasis. | [
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"... | A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. There was no vomiting or weight loss. Bowel movements were normal. Clinical examination at the time was unrevealing. An abdominal ultrasound examination was reported as normal. The patient’s insist... | EN100415 |
She was prepared for exploratory laparotomy. | [
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... | A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. There was no vomiting or weight loss. Bowel movements were normal. Clinical examination at the time was unrevealing. An abdominal ultrasound examination was reported as normal. The patient’s insist... | EN100415 |
The pancreas was explored through the gastrocolic omentum. | [
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... | A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. There was no vomiting or weight loss. Bowel movements were normal. Clinical examination at the time was unrevealing. An abdominal ultrasound examination was reported as normal. The patient’s insist... | EN100415 |
The body and tail of the pancreas including the tumour were resected. | [
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... | A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. There was no vomiting or weight loss. Bowel movements were normal. Clinical examination at the time was unrevealing. An abdominal ultrasound examination was reported as normal. The patient’s insist... | EN100415 |
The spleen was also removed. | [
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... | A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. There was no vomiting or weight loss. Bowel movements were normal. Clinical examination at the time was unrevealing. An abdominal ultrasound examination was reported as normal. The patient’s insist... | EN100415 |
The end of the pancreas was suture ligated. | [
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Her post-operative recovery was uneventful. | [
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... | A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. There was no vomiting or weight loss. Bowel movements were normal. Clinical examination at the time was unrevealing. An abdominal ultrasound examination was reported as normal. The patient’s insist... | EN100415 |
Histological examination of the specimen showed a well circumscribed ovoid tumour 60mm x 50mm across. | [
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... | A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. There was no vomiting or weight loss. Bowel movements were normal. Clinical examination at the time was unrevealing. An abdominal ultrasound examination was reported as normal. The patient’s insist... | EN100415 |
Sections revealed islands and trabeculae of regular cells with variable amounts of eosinophilic cytoplasm, mostly regular nuclei with indistinct nucleoli. | [
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... | A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. There was no vomiting or weight loss. Bowel movements were normal. Clinical examination at the time was unrevealing. An abdominal ultrasound examination was reported as normal. The patient’s insist... | EN100415 |
Areas of necrosis were present with hemorrhage. | [
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... | A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. There was no vomiting or weight loss. Bowel movements were normal. Clinical examination at the time was unrevealing. An abdominal ultrasound examination was reported as normal. The patient’s insist... | EN100415 |
A fibrous pseudo-capsule was noted around the tumour and the resection of the tumour appeared complete. | [
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... | A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. There was no vomiting or weight loss. Bowel movements were normal. Clinical examination at the time was unrevealing. An abdominal ultrasound examination was reported as normal. The patient’s insist... | EN100415 |
No capsular of vascular invasion was seen. | [
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] | A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. There was no vomiting or weight loss. Bowel movements were normal. Clinical examination at the time was unrevealing. An abdominal ultrasound examination was reported as normal. The patient’s insist... | EN100415 |
Immuno-peroxidase staining was positive for chromogranin A. | [
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Synaptophysin was strongly positive, CD10 was negative, Ki-67 was less than 2% positive and the mitotic count was between 2-20 per 10 hpf. | [
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... | A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. There was no vomiting or weight loss. Bowel movements were normal. Clinical examination at the time was unrevealing. An abdominal ultrasound examination was reported as normal. The patient’s insist... | EN100415 |
The staining reactions were confirmatory of a neuroendocrine carcinoma of the pancreas. | [
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... | A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. There was no vomiting or weight loss. Bowel movements were normal. Clinical examination at the time was unrevealing. An abdominal ultrasound examination was reported as normal. The patient’s insist... | EN100415 |
The final staging of the completely excised tumour was T3 N0 M0. | [
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] | A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. There was no vomiting or weight loss. Bowel movements were normal. Clinical examination at the time was unrevealing. An abdominal ultrasound examination was reported as normal. The patient’s insist... | EN100415 |
Following discharge, she was followed up regularly and remains symptom free. | [
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... | A 57 year old lady presented to a peripheral hospital with complaints of penetrating epigastric pain of a week’s duration. There was no vomiting or weight loss. Bowel movements were normal. Clinical examination at the time was unrevealing. An abdominal ultrasound examination was reported as normal. The patient’s insist... | EN100415 |
A CT Scan performed 2 years after surgery showed no evidence of tumour recurrence. | [
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A 3-day-old boy from Kosovo with dextro-transposition of the great arteries who developed progressive heart failure required an emergency arterial switch operation. | [
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Because of persistent pulmonary edema after completion of the arterial switch operation at our institution, the patient could not be weaned off mechanical ventilation. | [
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{... | A 3-day-old boy from Kosovo with dextro-transposition of the great arteries who developed progressive heart failure required an emergency arterial switch operation. Because of persistent pulmonary edema after completion of the arterial switch operation at our institution, the patient could not be weaned off mechanical ... | EN105551 |
Transthoracic echocardiography revealed an anomalous accelerated flow, indicating an anomalous systemic pulmonary shunt. | [
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Arterial catheterization revealed an abnormal bronchial artery originating from the left subclavian artery and bifurcating to both lungs. | [
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... | A 3-day-old boy from Kosovo with dextro-transposition of the great arteries who developed progressive heart failure required an emergency arterial switch operation. Because of persistent pulmonary edema after completion of the arterial switch operation at our institution, the patient could not be weaned off mechanical ... | EN105551 |
The anomalous ectatic bronchial artery was successfully occluded by coil embolization. | [
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The improvement of the patient's hemodynamic status resulted in an uneventful post-operative course. | [
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... | A 3-day-old boy from Kosovo with dextro-transposition of the great arteries who developed progressive heart failure required an emergency arterial switch operation. Because of persistent pulmonary edema after completion of the arterial switch operation at our institution, the patient could not be weaned off mechanical ... | EN105551 |
A 49-year-old white Caucasian woman presented with vaginal bleeding. | [
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... | A 49-year-old white Caucasian woman presented with vaginal bleeding. A pelvic examination revealed a cystic lesion arising from her cervix. Examination of a biopsy specimen revealed a poorly differentiated neoplasm, with sheets of small hyperchromatic cells, staining weakly for neuroendocrine markers. She was diagnosed... | EN105223 |
A pelvic examination revealed a cystic lesion arising from her cervix. | [
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Examination of a biopsy specimen revealed a poorly differentiated neoplasm, with sheets of small hyperchromatic cells, staining weakly for neuroendocrine markers. | [
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... | A 49-year-old white Caucasian woman presented with vaginal bleeding. A pelvic examination revealed a cystic lesion arising from her cervix. Examination of a biopsy specimen revealed a poorly differentiated neoplasm, with sheets of small hyperchromatic cells, staining weakly for neuroendocrine markers. She was diagnosed... | EN105223 |
She was diagnosed with small cell carcinoma and started on concurrent chemotherapy and radiation. | [
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... | A 49-year-old white Caucasian woman presented with vaginal bleeding. A pelvic examination revealed a cystic lesion arising from her cervix. Examination of a biopsy specimen revealed a poorly differentiated neoplasm, with sheets of small hyperchromatic cells, staining weakly for neuroendocrine markers. She was diagnosed... | EN105223 |
However, additional positive immunostaining for CD99 was strongly suggestive of Ewing's sarcoma. | [
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Fluorescence in situ hybridization revealed ESWR1 gene rearrangement, confirming Ewing's sarcoma. | [
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Our patient underwent surgery, which confirmed stage IIB Ewing's sarcoma. | [
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... | A 49-year-old white Caucasian woman presented with vaginal bleeding. A pelvic examination revealed a cystic lesion arising from her cervix. Examination of a biopsy specimen revealed a poorly differentiated neoplasm, with sheets of small hyperchromatic cells, staining weakly for neuroendocrine markers. She was diagnosed... | EN105223 |
She received adjuvant chemotherapy but died from progressive metastatic disease after four cycles. | [
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... | A 49-year-old white Caucasian woman presented with vaginal bleeding. A pelvic examination revealed a cystic lesion arising from her cervix. Examination of a biopsy specimen revealed a poorly differentiated neoplasm, with sheets of small hyperchromatic cells, staining weakly for neuroendocrine markers. She was diagnosed... | EN105223 |
This case report describes the condition of a 30-year-old man involved in a motor vehicle collision. | [
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Clinical examination, X-rays, and computed tomography scan revealed a posterior hip dislocation with an ipsilateral femoral head and mid-shaft fractures. | [
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The patient was treated by closed reduction of hip dislocation using a temporarily applied external fixator followed by intramedullary nailing of the femoral shaft. | [
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Achieving a closed reduction is a challenge with ipsilateral fractures but it should be favored over open reduction due to a lower risk of complications. | [
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The type of femoral head fracture, in this case, may have aided in an easier reduction. | [
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We present here a case of Macrophage activation syndrome associated with Griscelli syndrome type 2 in a 3-years-old male born of consanguineous parentage. | [
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... | We present here a case of Macrophage activation syndrome associated with Griscelli syndrome type 2 in a 3-years-old male born of consanguineous parentage. His birth histories, his familie social history and developmental milestones were unremarkable. He was born at full term with no antenatal or perinatal complications... | EN100372 |
His birth histories, his familie social history and developmental milestones were unremarkable. | [] | We present here a case of Macrophage activation syndrome associated with Griscelli syndrome type 2 in a 3-years-old male born of consanguineous parentage. His birth histories, his familie social history and developmental milestones were unremarkable. He was born at full term with no antenatal or perinatal complications... | EN100372 |
He was born at full term with no antenatal or perinatal complications, He was on exclusively breast-fed, food diversification was started at 6 months old, his weight, length and psychomotor development were within the normal range, the child was described as a good eater, was on a normal diet and was thriving appropria... | [
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... | We present here a case of Macrophage activation syndrome associated with Griscelli syndrome type 2 in a 3-years-old male born of consanguineous parentage. His birth histories, his familie social history and developmental milestones were unremarkable. He was born at full term with no antenatal or perinatal complications... | EN100372 |
Furthermore the boy presented a progressive abdominal distension since birth, progressive pallor and recurrent episodes of fever since 1 year of age. | [
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There was history of blood transfusions for last 2 months. | [
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On the other side there was no history of jaundice, vomiting, urinary or bowel complaints, bleeding from any site or neurological complaints. | [
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{... | We present here a case of Macrophage activation syndrome associated with Griscelli syndrome type 2 in a 3-years-old male born of consanguineous parentage. His birth histories, his familie social history and developmental milestones were unremarkable. He was born at full term with no antenatal or perinatal complications... | EN100372 |
On admission, he was very pale with silvery gray scalp hair, white eyelashes, he was hypotonic, tachycardic, fever of 40°C, lymphoadenopathy and hepato-splenomegaly. | [
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... | We present here a case of Macrophage activation syndrome associated with Griscelli syndrome type 2 in a 3-years-old male born of consanguineous parentage. His birth histories, his familie social history and developmental milestones were unremarkable. He was born at full term with no antenatal or perinatal complications... | EN100372 |
The blood count showed pancytopenia; 1980 white blood cells/µL (VN 4000-13 500/µL), neutrophils 820/µL, 910 cells/µL, hemoglobin (Hb) 6.3 g/dL (11.5-14 VN, 5 g/dL), platelets 44 000/µL (VN 150 000-400 000/µL), There were no giant cytoplasmic granules in leucocytes. | [
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... | We present here a case of Macrophage activation syndrome associated with Griscelli syndrome type 2 in a 3-years-old male born of consanguineous parentage. His birth histories, his familie social history and developmental milestones were unremarkable. He was born at full term with no antenatal or perinatal complications... | EN100372 |
The liver function tests were normal expect low albumin (2.1 mg/dL) and increased alkaline phosphatase (1196 mg/dL) with low fibrinogen (1.7g/l). | [
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... | We present here a case of Macrophage activation syndrome associated with Griscelli syndrome type 2 in a 3-years-old male born of consanguineous parentage. His birth histories, his familie social history and developmental milestones were unremarkable. He was born at full term with no antenatal or perinatal complications... | EN100372 |
Serum triglycerides, ferrintin and lactic dehydrogenase were very high; respectively 4.75g/L; 2763µg/L and 597U/L. the C reactive protein (CRP) was elevated at 83mg/l. | [
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... | We present here a case of Macrophage activation syndrome associated with Griscelli syndrome type 2 in a 3-years-old male born of consanguineous parentage. His birth histories, his familie social history and developmental milestones were unremarkable. He was born at full term with no antenatal or perinatal complications... | EN100372 |
A chest X-ray was normal while the abdominal ultrasound showed a hepatomegaly and a splenomegaly, free biliary ducts without ascites. | [
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... | We present here a case of Macrophage activation syndrome associated with Griscelli syndrome type 2 in a 3-years-old male born of consanguineous parentage. His birth histories, his familie social history and developmental milestones were unremarkable. He was born at full term with no antenatal or perinatal complications... | EN100372 |
Because of hepato-splenomegaly, pancytopenia, hyperferritinemia and hypofibrinogenemia the diagnosis of Macrophage activation syndrome was evoked indicating a bone marrow aspiration that showed numerous morphologically benign macrophages with haemophagocytic activity that comforting the diagnosis of a SAM according to ... | [
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Blood culture, urine examination, malarial serology, Kala Azar serology, viral serologies such as EBV, hepatitis A, B, C and human immunodeficiency virus HIV, serologies of rickettsia, syphilis and toxoplasmosa were negatives. | [
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Serologies of CMV and rubella showed an old immunization. | [
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] | We present here a case of Macrophage activation syndrome associated with Griscelli syndrome type 2 in a 3-years-old male born of consanguineous parentage. His birth histories, his familie social history and developmental milestones were unremarkable. He was born at full term with no antenatal or perinatal complications... | EN100372 |
The immunological tests such as antinuclear antibodies (ANA), anti-LKM1, anti-mitochondria and anti-smooth muscle antibodies were negatives. | [
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] | We present here a case of Macrophage activation syndrome associated with Griscelli syndrome type 2 in a 3-years-old male born of consanguineous parentage. His birth histories, his familie social history and developmental milestones were unremarkable. He was born at full term with no antenatal or perinatal complications... | EN100372 |
Because of the consanguineous family, notion of recurrent infection and the presence of silvery-gray color of the hair and eyebrows, diagnosis of Griscelli Syndrome was evoked directing a light microscopy examination of the hair that showed a large, irregular clumps of pigments characteristic of Griscelli Syndrome. | [
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The molecular biology showed mutation in RAB27A gene confirming the diagnosis of a Griscelli syndrome type 2. | [
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The first-line therapy in management of Macrophage activation syndrome complicating Griscelli syndrome type 2 was based on the parenteral administration of high doses of corticosteroids (methylprednisolone pulses 1g/0.73m 2 /day for 3 days then 60mg/m 2) with poor response; persisting with involvement of the 3 cell lin... | [
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Given the lack of response to steroids, Etoposide was started for 3 days associated with cyclophosphamide, the evolution was good with improvement of count blood cells, ferritin was lessening while the bone marrow showed decreased numerous of macrophages with low haemophagocytic activity. | [
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On the other side the infectious process was good managed by perfusion of Antibiotics such as Ceftazidim in combination with aminoside. | [
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The patient was sent home with prednisone and cyclosporine, He was placed on the list of bone marrow transplantation (BMT). | [
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A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. | [
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The patient's past medical history was non-significant. | [
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He was a student and had not received any medication. | [
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He had a pet dog and reported no recent travel. | [
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During physical examination on admission, vital signs were normal and he was febrile with a body temperature of 38°C. | [
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"type": "EVENT"
},
... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Abdominal examination revealed a tender palpable liver, with no signs of peritoneal irritation. | [
{
"id": "9158",
"offsets": [
10,
21
],
"role": "",
"semantic_type_id": "",
"text": "examination",
"type": "EVENT"
},
{
"id": "9173",
"offsets": [
22,
30
],
"role": "",
"semantic_type_id": "",
"text": "revealed",
"type": "EVENT"
},... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
The remainder of physical examination was unremarkable. | [
{
"id": "9218",
"offsets": [
26,
37
],
"role": "",
"semantic_type_id": "",
"text": "examination",
"type": "EVENT"
},
{
"id": "9233",
"offsets": [
42,
54
],
"role": "",
"semantic_type_id": "",
"text": "unremarkable",
"type": "EVENT"
... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Abnormal laboratory results on admission included a white blood cell count (WBC) of 20.830 (4-10.5x10³/μL), elevated C-reactive protein (CRP) level (28mg/dl, normal ≤0.5mg/dl), slightly elevated alanine aminotransferase (ALT) of 56 IU/L (normal 5-40 IU/L), and lactic dehydrogenase (LDH) of 255 IU/L (normal <225 IU/L). | [
{
"id": "9248",
"offsets": [
20,
27
],
"role": "",
"semantic_type_id": "",
"text": "results",
"type": "EVENT"
},
{
"id": "9263",
"offsets": [
69,
74
],
"role": "",
"semantic_type_id": "",
"text": "count",
"type": "EVENT"
},
{
... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Alkaline phosphatase (ALP) was normal. | [
{
"id": "9368",
"offsets": [
9,
20
],
"role": "",
"semantic_type_id": "",
"text": "phosphatase",
"type": "EVENT"
},
{
"id": "9383",
"offsets": [
22,
25
],
"role": "",
"semantic_type_id": "",
"text": "ALP",
"type": "EVENT"
},
{
... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Abdominal ultrasonography on admission revealed a mildly enlarged liver and spleen and the presence of 2 sizable, hypoechoic lesions. | [
{
"id": "9398",
"offsets": [
10,
25
],
"role": "",
"semantic_type_id": "",
"text": "ultrasonography",
"type": "EVENT"
},
{
"id": "9413",
"offsets": [
39,
47
],
"role": "",
"semantic_type_id": "",
"text": "revealed",
"type": "EVENT"
... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Abdominal computed tomography (CT) scan revealed the 2 aforementioned lesions in diameter of 5.6cm at the left liver lobe and 5.2cm in the right lobe. | [
{
"id": "9443",
"offsets": [
35,
39
],
"role": "",
"semantic_type_id": "",
"text": "scan",
"type": "EVENT"
},
{
"id": "9458",
"offsets": [
40,
48
],
"role": "",
"semantic_type_id": "",
"text": "revealed",
"type": "EVENT"
},
{
... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
The lesions were hypodense and presented peripheral enhancement after intravenous contrast, similar to the morphology of hepatic abscesses. | [
{
"id": "9503",
"offsets": [
4,
11
],
"role": "",
"semantic_type_id": "",
"text": "lesions",
"type": "EVENT"
},
{
"id": "9518",
"offsets": [
17,
26
],
"role": "",
"semantic_type_id": "",
"text": "hypodense",
"type": "EVENT"
},
{... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
The patient was admitted for further evaluation and treatment. | [
{
"id": "9578",
"offsets": [
16,
24
],
"role": "",
"semantic_type_id": "",
"text": "admitted",
"type": "EVENT"
},
{
"id": "9593",
"offsets": [
37,
47
],
"role": "",
"semantic_type_id": "",
"text": "evaluation",
"type": "EVENT"
},
... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Culture guided antimicrobials and appropriate drainage was our first option. | [
{
"id": "9623",
"offsets": [
15,
29
],
"role": "",
"semantic_type_id": "",
"text": "antimicrobials",
"type": "EVENT"
},
{
"id": "9638",
"offsets": [
46,
54
],
"role": "",
"semantic_type_id": "",
"text": "drainage",
"type": "EVENT"
... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Empiric antibiotic therapy with intravenous ciprofloxacin (400mg every 12 hours), and metronidazole (500mg every 8 hours) was initiated. | [
{
"id": "9653",
"offsets": [
19,
26
],
"role": "",
"semantic_type_id": "",
"text": "therapy",
"type": "EVENT"
},
{
"id": "9668",
"offsets": [
126,
135
],
"role": "",
"semantic_type_id": "",
"text": "initiated",
"type": "EVENT"
}
] | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
All cultures resulted negative. | [
{
"id": "9683",
"offsets": [
4,
12
],
"role": "",
"semantic_type_id": "",
"text": "cultures",
"type": "EVENT"
},
{
"id": "10921",
"offsets": [
22,
30
],
"role": "",
"semantic_type_id": "",
"text": "negative",
"type": "RML"
}
] | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Initially, we performed percutaneous sonographic (U/S) guided aspiration into the left hepatic abscess cavity. | [
{
"id": "9698",
"offsets": [
62,
72
],
"role": "",
"semantic_type_id": "",
"text": "aspiration",
"type": "EVENT"
},
{
"id": "10753",
"offsets": [
78,
109
],
"role": "",
"semantic_type_id": "",
"text": "the left hepatic abscess cavity",
... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
A thick, purulent material of 40cc was drained and sent for culture. | [
{
"id": "9713",
"offsets": [
39,
46
],
"role": "",
"semantic_type_id": "",
"text": "drained",
"type": "EVENT"
},
{
"id": "9728",
"offsets": [
51,
55
],
"role": "",
"semantic_type_id": "",
"text": "sent",
"type": "EVENT"
}
] | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Microbiology revealed a Gram-negative bacterium that presented slow growth. | [
{
"id": "9743",
"offsets": [
0,
12
],
"role": "",
"semantic_type_id": "",
"text": "Microbiology",
"type": "EVENT"
},
{
"id": "9758",
"offsets": [
13,
21
],
"role": "",
"semantic_type_id": "",
"text": "revealed",
"type": "EVENT"
},... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
On the 5th and 8th days of admission, we performed CT guided catheter drainage of both abscesses. | [
{
"id": "9803",
"offsets": [
27,
36
],
"role": "",
"semantic_type_id": "",
"text": "admission",
"type": "EVENT"
},
{
"id": "9818",
"offsets": [
70,
78
],
"role": "",
"semantic_type_id": "",
"text": "drainage",
"type": "EVENT"
},
... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Meanwhile irregular spikes of fever with daytime variation accompanied by night sweats persisted. | [
{
"id": "9833",
"offsets": [
30,
35
],
"role": "",
"semantic_type_id": "",
"text": "fever",
"type": "EVENT"
},
{
"id": "9848",
"offsets": [
49,
58
],
"role": "",
"semantic_type_id": "",
"text": "variation",
"type": "EVENT"
},
{
... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Ciprofloxacin discontinued and meropenem at a dose of 1gr every 8 hours administered. | [
{
"id": "9893",
"offsets": [
0,
13
],
"role": "",
"semantic_type_id": "",
"text": "Ciprofloxacin",
"type": "EVENT"
},
{
"id": "9908",
"offsets": [
14,
26
],
"role": "",
"semantic_type_id": "",
"text": "discontinued",
"type": "EVENT"... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Thorough screening for other possible sources of infection, resulted negative. | [
{
"id": "9938",
"offsets": [
9,
18
],
"role": "",
"semantic_type_id": "",
"text": "screening",
"type": "EVENT"
},
{
"id": "10674",
"offsets": [
49,
58
],
"role": "",
"semantic_type_id": "C3714514",
"text": "infection",
"type": "CLIN... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Transthoracic echocardiography was negative for vegetations and showed mild mitral regurgitation. | [
{
"id": "9953",
"offsets": [
14,
30
],
"role": "",
"semantic_type_id": "",
"text": "echocardiography",
"type": "EVENT"
},
{
"id": "9968",
"offsets": [
48,
59
],
"role": "",
"semantic_type_id": "",
"text": "vegetations",
"type": "EVE... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Entamoeba histolytica Abs, echinococcus Abs, leismania Abs, brucella Abs were negative. | [
{
"id": "10013",
"offsets": [
0,
9
],
"role": "",
"semantic_type_id": "",
"text": "Entamoeba",
"type": "EVENT"
},
{
"id": "10028",
"offsets": [
27,
39
],
"role": "",
"semantic_type_id": "",
"text": "echinococcus",
"type": "EVENT"
... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Gastrointestinal endoscopic evaluation was unrevealing. | [
{
"id": "10073",
"offsets": [
28,
38
],
"role": "",
"semantic_type_id": "",
"text": "evaluation",
"type": "EVENT"
},
{
"id": "10945",
"offsets": [
43,
54
],
"role": "",
"semantic_type_id": "",
"text": "unrevealing",
"type": "RML"
... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
The patient was also HIV negative and no other immunodeficiency conditions were identified. | [
{
"id": "10088",
"offsets": [
25,
33
],
"role": "",
"semantic_type_id": "",
"text": "negative",
"type": "EVENT"
},
{
"id": "10103",
"offsets": [
64,
74
],
"role": "",
"semantic_type_id": "",
"text": "conditions",
"type": "EVENT"
}... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Eventually, the isolate identified by the Vitek 2 automated system and classified as A. aphrophilus. | [
{
"id": "10133",
"offsets": [
24,
34
],
"role": "",
"semantic_type_id": "",
"text": "identified",
"type": "EVENT"
},
{
"id": "10148",
"offsets": [
71,
81
],
"role": "",
"semantic_type_id": "",
"text": "classified",
"type": "EVENT"
... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
To confirm the identification of the strain we performed matrix assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). | [
{
"id": "10163",
"offsets": [
3,
10
],
"role": "",
"semantic_type_id": "",
"text": "confirm",
"type": "EVENT"
},
{
"id": "10178",
"offsets": [
37,
43
],
"role": "",
"semantic_type_id": "",
"text": "strain",
"type": "EVENT"
},
{
... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
The sensitivity test was performed with minimal inhibitory concentration (MIC) test strips; the isolate's susceptibility was to ceftriaxone ≤0.125 (S), cefepime ≤0.5 (S), ciprofloxacin ≤0.125 (S), gentamycin ≤0.5 (S), amikacin ≤0.125 (S) and to meropenem ≤0.032 (S). | [
{
"id": "10208",
"offsets": [
16,
20
],
"role": "",
"semantic_type_id": "",
"text": "test",
"type": "EVENT"
},
{
"id": "10223",
"offsets": [
106,
120
],
"role": "",
"semantic_type_id": "",
"text": "susceptibility",
"type": "EVENT"
... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Percutaneous drainage of both abscesses, combined with antimicrobial treatment, was successful and the patient's clinical condition improved. | [
{
"id": "10328",
"offsets": [
13,
21
],
"role": "",
"semantic_type_id": "",
"text": "drainage",
"type": "EVENT"
},
{
"id": "10343",
"offsets": [
69,
78
],
"role": "",
"semantic_type_id": "",
"text": "treatment",
"type": "EVENT"
},... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Thankfully, no surgical procedure was required. | [
{
"id": "10403",
"offsets": [
24,
33
],
"role": "",
"semantic_type_id": "",
"text": "procedure",
"type": "EVENT"
}
] | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
The drains were removed immediately the fluid from the abscess cavities became clear. | [
{
"id": "10418",
"offsets": [
16,
23
],
"role": "",
"semantic_type_id": "",
"text": "removed",
"type": "EVENT"
},
{
"id": "10433",
"offsets": [
79,
84
],
"role": "",
"semantic_type_id": "",
"text": "clear",
"type": "EVENT"
},
{
... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
Meropenem was administered for a total of 2 weeks. | [
{
"id": "10448",
"offsets": [
14,
26
],
"role": "",
"semantic_type_id": "",
"text": "administered",
"type": "EVENT"
},
{
"id": "11032",
"offsets": [
31,
49
],
"role": "",
"semantic_type_id": "",
"text": "a total of 2 weeks",
"type":... | A 23-year-old previously healthy man, presented to the hospital's emergency department, with a 3-day history of high-grade fever up to 40°C and upper right abdominal pain. The patient's past medical history was non-significant. He was a student and had not received any medication. He had a pet dog and reported no recen... | EN100399 |
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