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| license: apache-2.0 |
| language: |
| - en |
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| # NeuroBOLT EEG-fMRI ROI Dataset |
| **Short name:** `neurobolt-rest` |
| **Modalities:** EEG (simultaneous with fMRI), fMRI ROI time series |
| **Setting:** Resting-state (eyes closed) |
| **Subjects / Scans:** 22 participants, 29 fMRI scans (7 participants with two scans) |
| <!-- **Contact for extended data (task-condition or higher-res ROIs):** yamin.li@vanderbilt.edu |
| --> |
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| ## 🧠 Overview |
| This dataset provides synchronized resting-state **EEG** and **BOLD fMRI ROI time series** collected **simultaneously** from healthy adults. It is intended for research on **NeuroAI, cross-modal modeling (EEG-fMRI), multimodal fusion, and hemodynamic modeling**. |
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| We release: |
| - Preprocessed **fMRI ROI time series** (DiFuMo parcellation, n=64). |
| - Preprocessed and resampled **EEG** time series aligned to fMRI. |
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| *For **task-condition data**, **higher-resolution DiFuMo ROIs** (>64), or any inquiries, please contact **yamin.li@vanderbilt.edu**.* |
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|
| ## 📖 Data Collection Summary |
| - **Participants:** 22 healthy volunteers. |
| - **Sessions:** Two 20-minute resting sessions per participant (eyes closed); final dataset contains **29 scans** after artifact exclusion. |
| - **Ethics:** Written informed consent obtained. Procedures approved by the Institutional Review Board (IRB). |
|
|
| ### fMRI |
| - **Scanner:** 3T |
| - **Sequence:** Multi-echo gradient-echo EPI |
| - **TR:** 2100 ms |
| - **Condition:** Rest (eyes closed) |
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|
| ### EEG |
| - **System:** MR-compatible, 32-channel (10–20), **FCz** reference (BrainAmps MR, Brain Products GmbH) |
| - **Sampling rate:** 5 kHz, synchronized to the **scanner’s 10 MHz clock** (facilitates MR gradient artifact reduction) |
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| ## 🔩 Preprocessing Summary |
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| ### fMRI → ROI time series |
| - **Parcellation:** DiFuMo (n = 64) with **2 additional global signals** |
| - *global signal clean (cleaned whole-brain average signal, with confounds regressed)* |
| - *global signal raw (unprocessed whole-brain average signal)* |
| - **Confound regression:** Motion regressors removed |
| - **Temporal filtering:** Low-pass filter applied at < 0.15 Hz |
| - **Normalization:** Demeaned and scaled by the **95th percentile** of the absolute amplitude (per ROI) |
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| In the paper we evaluated **7 representative ROIs** spanning diverse spatial and functional domains: |
| - **Primary sensory:** *Cuneus*, *Heschl’s gyrus* |
| - **High-level cognitive:** *Precuneus anterior*, *Middle frontal gyrus anterior* |
| - **Subcortical:** *Putamen*, *Thalamus* |
| - **Global:** *global signal clean* |
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|
| ### EEG |
| - Channels: ECG/EOG/EMG **removed** → remaining **26 scalp channels** |
| - Resampling: **5 kHz → 200 Hz** (retains <100 Hz content, improves efficiency) |
| - Alignment: synchronized to fMRI acquisition for one-to-one pairing with BOLD time points |
| - Model input convention (if used): **16-second EEG windows** preceding each fMRI TR (covers HRF peak and variance) |
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| *Detailed acquisition and artifact-reduction procedures are documented in the [NeuroBOLT paper’s Appendix D](https://openreview.net/pdf?id=y6qhVtFG77).* |
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| ## ⛳ Model Checkpoints |
| - Model checkpoints for selected brain regions are available for reproducing our results: |
| 👉 [**Hugging Face Repository**](https://huggingface.co/ssssssup/NeuroBOLT/tree/main) |
| - A step-by-step tutorial can be found here: |
| 📘 [**Google Colab Notebook**](https://colab.research.google.com/drive/1e7mfxQqth4mcfqlhTypgB5Q0gYPNbT-y?usp=sharing) |
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| ## 📚 Dataset Citation |
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| If you use our dataset in your research or publications, please cite the following paper: |
|
|
| ```bibtex |
| @inproceedings{ |
| li2024neurobolt, |
| title={Neuro{BOLT}: Resting-state {EEG}-to-f{MRI} Synthesis with Multi-dimensional Feature Mapping}, |
| author={Yamin Li and Ange Lou and Ziyuan Xu and Shengchao Zhang and Shiyu Wang and Dario J. Englot and Soheil Kolouri and Daniel Moyer and Roza G Bayrak and Catie Chang}, |
| booktitle={The Thirty-eighth Annual Conference on Neural Information Processing Systems}, |
| year={2024}, |
| url={https://openreview.net/forum?id=y6qhVtFG77} |
| } |
| |
| --- |
| license: Apache-2.0 |
| --- |
