README.md

Kircher et al. (2019) Evaluator Container for Genomic API for Model Evaluation (GAME)

Authors Nikita Penzin, Ivan V Kulakovskiy, Ilya Vorontsov, Dmitry Penzar

Evaluator container for Kircher et. al (2019) MPRA dataset. A total of 44,647 single-nucleotide variants (SNVs) located in 21 regulatory elements, 10 promoters and 11 enhancers across 12 cell lines.

Kircher, M., Xiong, C., Martin, B. et al. Saturation mutagenesis of twenty disease-associated regulatory elements at single base-pair resolution. Nat Commun 10, 3583 (2019). https://doi.org/10.1038/s41467-019-11526-w

kircher_evaluator.sif contains all dependencies and scripts required for the Evaluator container to read in the raw MPRA data, parse into the correct API format, and connect with any Predictor container via RestAPI.

Additional information can be found here: https://github.com/de-Boer-Lab/Genomic-Model-Evaluation-API