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PMC4711340_02_eplasty16e02_fig2.jpg
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Case 2 on the first day of onset. She presented with a diffuse rash on the upper part of her body.
On postoperative day 8, the patient presented with a fever of 40.0 C, a diffuse rash on the upper part of her body, hypotension, and vomiting (Fig 2).
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Swelling over lateral end of left clavicle.
A 60 year old man presented to our department with pain and swelling over lateral end of left clavicle (Fig. 1, Fig. 2).
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X-ray showing expansile radiolucent lesion arising from lateral end of left clavicle.
We got a plain radiograph which revealed which an expansile radiolucent lesion arising from lateral end of left clavicle (Fig. 3).
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Magnetic resonance imaging showing swelling arising from clavicle.
MRI was obtained which also suggested giant cell tumour (Fig. 4).
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Intraoperative picture after excising the mass.
After proper investigations and pre anaesthetic clearance, a wide excision of the mass along with 3 cm of the healthy tissue was done (Fig. 5, Fig. 6).
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Showing good range of motion after partial claviculectomy.
A post operative x-ray was obtained (Fig. 7).
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The CT scan reveals interval follows radical nephrectomy and lymphodectomy and increase in caval node at renal hilum on right side measuring 29 mm in short axis. A simple renal cortical cyst evident at the lower pole of the left kidney.
His follow up CT three months following radical nephrectomy indicated disease recurrence (Fig. 2).
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The image shows a 17 mm high intensity area in the pons on T2-weighted (A) and diffusion-weighted (B) magnetic resonance imaging (MRI) of the brain.
Brain magnetic resonance imaging (MRI) revealed a non-enhancing, high-intensity area of 17 mm in diameter in the pons on T2- and diffusion-weighted imaging (Figure 1A and B); however, no abnormal neurological signs were observed.
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Pathological specimens.. Notes: (A) Skin biopsy specimen taken from the lower abdomen reveals proliferation of large lymphoma cells filling the vessels of hypodermic adipose tissue. (B) Numerous lymphoma cells with irregular nuclear contours and large nucleoli clustered are seen in small vessel lumens. Hematoxylin and ...
All specimens revealed large B lymphoma cells within small veins and capillaries of the subcutaneous fat tissues but not outside the vessels (Figure 2A and B).
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Magnetic resonance imaging (MRI) of the brain after receiving chemotherapy.. Notes: Pontine lesion on T2-weighted (A) and diffusion-weighted (B) MRI of the brain completely resolved after eight cycles of rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone therapy.
After eight cycles of R-CHOP therapy, the pontine lesion had completely disappeared (Figure 4A and B).
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Transthoracic echocardiography (four-chamber view) showing an echogenic mass attached to the posterior leaflet of the mitral valve (MV) measuring 2.3 cm x 1.3 cm
An urgent echocardiography revealed an echogenic mass attached to the posterior leaflet of the mitral valve measuring 2.3 cm x 1.3 cm [Figure 1] with a pulmonary artery pressure of 44 mmHg.
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Intraoperative transesophegeal echocardiography (color flow Doppler, four-chamber view) showing prosthetic MV repair with severe mitral regurgitation jet
Intraoperative transesophegeal echocardiography confirmed an echogenic mass on the prosthetic mitral valve with severe mitral regurgitation [Figure 2].
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Pictograph of mitral annuloplasty ring with remnant vegetation and part of the excised native mitral leaflet
There was a large mass on the ventricular surface of the mitral valve [Figure 3].
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Minor's test: bluish staining show locations where there is sudoresis
The Minor's test was carried out to show profuse sudoresis contrasting with the anhidrotic areas (presence of blue color on places where there is sudoresis - Figure 2).
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Histological findings showed increased well-differentiated tubular adenocarcinoma within a tubular adenoma (hematoxylin and eosin, 100x).
A horizontal and vertical cut margin was negative (Fig. 1).
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Operative procedure and intraoperative findings. (a) Intraoperative photograph showing that the S2 nerve root (double arrowheads) was compressed by the cyst component (white asterisk). (b) Closer observation revealed that the cyst wall (white asterisk) contains the S3 nerve root (double arrows). (c and d) After excisio...
At surgery, the S3 nerve root was enveloped within cyst wall and the S2 nerve root was clearly compressed [Figure 3a and b]. Partial resection of the cyst wall and imbrication of residual tissue was performed [Figure 3c]. An inlet from the subarachnoid space was identified, and its obliteration was confirmed by a Valsa...
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Gross-grey white mass.
The cut surface was grey-white solid homogeneous [Figure 1].
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M/E showing squamous and spindle cell component (H & E Stain; 10x).
Microscopic examination revealed a tumour composed of proliferating atypical bipolar spindle cells and small nests of squamous epithelial cells [Figure 2].
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M/E showing spindle cells arranged in fascicles (H & E Stain; 10x).
Malignant spindle cells, arranged in fascicles [Figures 3 and 4], formed the main bulk of the tumour.
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M/E showing spindle cell component (H & E Stain; 40x).
Malignant spindle cells, arranged in fascicles [Figures 3 and 4], formed the main bulk of the tumour.
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M/E showing epithelial pearl (H & E Stain; 10x).
At a few foci, small nests of malignant squamous epithelial cells and epithelial pearls were seen [Figure 5].
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IHC showing spindle cells strongly positive for vimentin (10x).
On immunohistochemistry, vimentin was strongly positive in the spindle cell component [Figure 6] and negative in the epithelial component.
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IHC showing spindle cells focal positivity for cytokeratin (10x).
Cytokeratin was focally positive in spindle cell component [Figure 7] and strongly positive in the epithelial component [Figure 8].
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IHC showing squamous cells positive for cytokeratin (10x).
Cytokeratin was focally positive in spindle cell component [Figure 7] and strongly positive in the epithelial component [Figure 8].
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Imaging materials of the patient during the anti-PD-1 treatment.. Notes: MRI showed multiple metastases occurred in the liver (A), spleen (B), and brain (C and D). A chest CT scan of the thorax showed lung lesion (E) before and (F) ~5 days after three cycles of nivolumab treatment. Arrows indicate the lesions.. Abbrevi...
Further examinations, including nuclear magnetic resonance imaging of his head, pathological examination, and positron emission tomography-computed tomography were conducted, showing multiple metastases in his brain, lymph nodes, liver, spleen, adrenal gland, and humerus (Figure 1A-E). A chest computed tomography exami...
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Several irregular slow waves with medium to high amplitudes were recorded in the right temporal leads, which spread to other leads and showed sharp waves (shown by the red arrow).
The electroencephalography (EEG)showed irregular slow waves with medium to high amplitudes in the right temporal lobe, which spread to the other lobes and showed sharp waves (Figure 1).
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(A) Increased signal intensity was seen on the T2-weighted FLAIR imaging in the right medial temporal lobe (shown by the red arrow). (B) Gadolinium-enhanced MRI of the brain showed mild to moderate cord enhancement in the right temporal lobe (shown by the red arrow). (C) The brain MRA did not show vascular stenosis or ...
T2-weighted and FLAIR imaging in the medial temporal lobe (Figure 2A). The gadolinium-enhanced MRI of the brain showed mild to moderate cord enhancement in the right temporal lobe (Figure 2B). However, the results revealed no abnormalities (Figure 2C). Moreover, a repeat of the brain MRI showed no abnormality (Figure 2...
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A repeat of the EEG showed no irregular slow waves and sharp waves emission. *** means uV, the unit of measurement of electromyography (EMG).
In addition, a repeat of the EEG showed no epileptiform wave emission (Figure 3).
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The changes in syphilis and LGI1 antibodies over the course of syphilitic treatment.
Changes in TPPA, RPR, and LGI1 antibodies during the syphilitic treatment are shown in Figure 4.
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(A) Two-dimensional ultrasound in 34th gestational week, on the axial and sagittal planes, showing the fetal goiter (arrows). (B) Color Doppler showing exuberant and uniform vascularization throughout the fetal thyroid.
A 41-year-old secundigravida with normal thyroid function, referred with 34 weeks of gestation after ultrasound exam showed a suspected fetal goiter, which proved to be a solid anterior neck mass with uniform vascularization throughout, particularly in the central region (Fig. 1).
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Three-dimensional ultrasound in the rendering mode showing the fetal neck mass (A) and magnetic resonance image acquired in the sagittal view (B) showing the fetal goiter (arrow) in T2-weighted sequences.
Fetal MRI was conducted and corroborated the diagnosis of goiter (Fig. 2).
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Gross necropsy: lung tumours in an Asiatic lion with haemangiosarcoma.
Gross post-mortem examination revealed a normal body condition with a body weight of 140 kg and the following salient findings: anaemic mucosae; 10 litres of blood in the abdominal cavity; pale-coloured pancreas and spleen; multiple nodular lung masses (a few mm to 10 cm diameter, filled with blood clots) (Fig. 1); mul...
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Gross necropsy: liver tumours in an Asiatic lion with haemangiosarcoma.
Mitotic figures ranged from 1 to 4 per high power field.
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Aspect of the proximal interphalangeal joint right index.
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Multiple osteochondromas of the lower legs - radiological aspect.
The X-ray of inferior limbs revealed multiple metaphyseal osteochondromas of the distal femur, proximal tibia, and fibula of the 3rd right metatarsal bone, and proximal and medial phalanges of the 2nd, 3rd. and 4th right toes (Fig. 2, 3 and 4).
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Enhaced CT scan 3 months later: ectasic aorta with stable hematoma
On the 3 months follow up contrast CT scan (Figure 3), there was no aortic dissection or aneurysm.
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Findings of chest computed tomography (CT) before and after treatment with pembrolizumab. (A) Chest CT shows a 60-mm irregularly shaped peripheral mass in the left upper lobe. (B) Chest CT shows a 10-mm irregularly shaped peripheral nodule in the right lower lobe. (C, D) After treatment with pembrolizumab for 13 cycles...
A 71-year-old woman presented with a chest computed tomography (CT) finding of left upper (Fig. 1A) and right lower (Fig. 1B) lung field nodules. After 13 cycles of pembrolizumab every 3 weeks, chest CT revealed a dramatic decrease in the size of the lesion in the left upper lobe (Fig. 1C), but the size of the lesion i...
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Endobronchial ultrasound with a guide sheath (EBUS-GS) and computed tomography-guided transthoracic needle biopsy (CTNB). (A) EBUS-GS was performed on the left upper lesion under X-ray fluoroscopy guidance. (B) CTNB was performed on the right lower lesion.
Left upper lung field nodule was diagnosed by endobronchial ultrasound with a guide sheath as squamous cell carcinoma with high programmed death-ligand 1 (PD-L1) expression (70%) (Fig. 2A). 18F-fluoro-2-deoxyglucose positron emission tomography showed uptake in both nodules. Because the treatment effect differed betwee...
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Pathological specimens from computed tomography-guided transthoracic needle biopsy (CTNB) and surgical procedure. (A) Photomicrographs of the CTNB right lower lesion specimens show squamous cell carcinoma with marked eosinophilic infiltration. (B) Surgically operated right lower lesion specimens after treatment with be...
The eosinophil count in surgical tissue was markedly reduced compared with that in preoperative CTNB tissue (Fig. 3A and B).
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Computed Tomography of chest, abdomen, and pelvis of patients 1, 2, and 4. (A) Patient 1: splenic nodule indicated by arrow. (B) Patient 1: right sided pulmonary lesion indicated by arrow. (C) Patient 2: hepatosplenomegaly. (D) Patient 4: right upper lobe pulmonary lesion.
Imaging revealed a large consolidation in the right upper lobe and enlarged lymph nodes ( Figure 1D ).
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Computed Tomography of chest, abdomen, and pelvis of patients 1, 2, and 4. (A) Patient 1: splenic nodule indicated by arrow. (B) Patient 1: right sided pulmonary lesion indicated by arrow. (C) Patient 2: hepatosplenomegaly. (D) Patient 4: right upper lobe pulmonary lesion.
Imaging revealed a large consolidation in the right upper lobe and enlarged lymph nodes ( Figure 1D ).
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Urgent CT scan on day 2 post intubation and during acute deterioration (A) sagittal plane showing stable lung infiltrates and significant subcutaneous emphysema, (B) coronal plan showing an intact airway.
Clinical examination and urgent chest X-ray did not support any deterioration from the COVID-19 previously noted infiltrates neither provided a plausible cause for the surgical emphysema (Figure 2A). Additionally, no pneumothorax was diagnosed and the previously noted COVID-19 infiltrates were stable (Figure 2B).
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Bronchoscopy images showing (A) the laceration at 5 o'clock mid trachea, (B) normal rest of bronchial tree.
No other signs of penetration through the airways were noted (Figure 3).
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Dose distribution of planning axial heavy T2-weighted magnetic resonance imaging for treatment planning to the left trigeminal nerve (arrow) from a copy of printed images from old medical records. Fourth ventricle (arrow head).
She received 45 Gy at 50% isodose at the proximal cisternal extent of the left trigeminal nerve [Figure 1].
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Magnetic resonance imaging (a and b) at the first emergency department, and digital subtraction angiography before (c) and after (d) mechanical embolectomy. Diffusion-weighted image (a) shows a hyperintensity in the left insular cortex and a slight hyperintensity in the left middle cerebral artery territory. Magnetic r...
MCA territory [Figure 2a]. Magnetic resonance angiography (MRA) revealed occlusion of the horizontal segment of the left MCA [Figure 2b]. MCA occlusion, even after t-PA injection [Figure 2c]. Mechanical thrombectomy was then performed using the Solitaire FR/2 revascularization device (Medtronic, Minneapolis, MN, USA; o...
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Computed tomography just after thrombectomy shows subarachnoid hemorrhage and a hematoma in the left cerebellar hemisphere (a and b). Computed tomography angiography could not confirm the presence of aneurysms (c and d).
Brain CT performed immediately after mechanical thrombectomy revealed subarachnoid hemorrhage (SAH) with a hematoma in the left cerebellar hemisphere [Figure 3a and b]. As CT angiography (CTA) could not confirm the presence of an aneurysm [Figure 3c and d], DSA of the posterior cerebral circulation was performed, and i...
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Cerebral angiography of the posterior cerebral circulation performed after computed tomography shows aneurysm-like dilatation in the peripheral portion of the left circumflex branch at the distal position of the anterior inferior cerebellar artery. Coil embolization is performed for aneurysmal dilatation. (a) Cerebral ...
As CT angiography (CTA) could not confirm the presence of an aneurysm [Figure 3c and d], DSA of the posterior cerebral circulation was performed, and it revealed a small irregular-shaped aneurysm at the branching site of the left circumflex branch of the anterior inferior cerebellar artery [Figure 4a]. Thus, we treated...
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Nodular opacities in left upper zone periphery on chest X-ray (posteroanterior view).
The patient had just been prescribed daily rifampicin 600 mg, isoniazid 300 mg, ethambutol 1.6 g, pyrazinamide 1.75 g (i.e., standard RHEZ combination therapy for TB of uncertain origin and resistance, according to his weight of 98.3 kg) and pyridoxine 10 mg after increased nodular opacities in the left upper zone were...
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Nodular opacities in left upper zone periphery on chest X-ray (apical lordotic view).
The patient had just been prescribed daily rifampicin 600 mg, isoniazid 300 mg, ethambutol 1.6 g, pyrazinamide 1.75 g (i.e., standard RHEZ combination therapy for TB of uncertain origin and resistance, according to his weight of 98.3 kg) and pyridoxine 10 mg after increased nodular opacities in the left upper zone were...
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Electrocardiogram showing normal sinus rhythm.
A full blood count, liver function test, thyroid function test, drug screen, troponin I, electrocardiogram (Figure 3), and a two-dimensional echocardiography were performed.
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(A) Clinical course. (B) Carbohydrate antigen 19-9 (CA19-9) change curve.
Urine examination revealed 375/mul white blood cells (WBCs) in the urine ( Figure 1 ). However, the patient's tumor indicators increased due to the discontinuation of lenvatinib and PD-1 antibody ( Figure 1 ). One month after the second operation, the patient's tumor indicators decreased and then increased again ( Figu...
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(A) October 22, 2019: magnetic resonance cholangiopancreatography showed the density of the soft tissue under the capsule of the right lobe of the liver. The possibility of metastasis was considered. (B) November 4, 2020: discovery of new lesions; tumor metastasis was considered (PET/CT showed nodular thickening of the...
Imaging examinations also revealed new lesions located on the right posterior lobe of the liver and above the duodenum on the right side of the pancreatic head in the abdominal cavity ( Figure 2 ).
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Histopathological findings. (A) was taken at 10x, and (B) was taken at 20x.
The result of the bladder biopsy indicated chronic inflammation of mucosal tissue, mucosal erosion in some areas, and proliferation of granulation tissues and fibroblasts ( Figure 3 ).
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(a) Sagittal short T1 inversion recovery (STIR)magnetic resonance (MR) image demonstrates flow related artifact along the right lateral aspect of the spinal canal at the C5-C6 level producing a lamellated chemical shift appearance (arrow). (b) Axial volumetric T1 fat suppressed post contrast MR image at the level of th...
Several MRI sequences also demonstrated flow related artifact within the area of extradural enhancement [Figures 1a and b]. CT angiography (CTA) was then obtained demonstrating multilevel asymmetric venous epidural enhancement spanning C4-C6 with a focal extradural venous pouch at the C5-C6 level [Figures 1c and d].
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(a) Selective catheter angiography of the deep cervical branch of the costocervical trunk. This early/mid arterial phase shows a fistulous point (arrow) leading to two large dilated venous pouches draining early to the deep cervical venous plexus (arrowhead). (b) Native oblique image at the end of treatment showing bot...
There was a smaller contributor from the inferior thyroid branch of the thyrocervical trunk [Figure 2a]. Onyx 18 was then infused upstream of the coil and allowed to disperse throughout the fistulous network in the typical fashion of "lava flow." At the conclusion of the embolization, the fistula appears completely obl...
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(a) Axial volumetric T1 fat suppressed post contrast magnetic resonance (MR) image and (b) Sagittal short T1 inversion recovery MR image demonstrate no residual venous enhancement or mass effect. The previously visualized flow-related artifact is no longer present.
An MRI and CTA were repeated at 6-week postoperatively which demonstrated complete obliteration of the C6 AVF [Figures 3a and b].
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Upper gastrointestinal series; arrow shows compression effect on posterior aspect of esophagus at the level of aorta arc suggestive of aberrant right subclavian artery
The infant's upper gastrointestinal (GI) series showed nasopharyngeal regurgitation and compression effect on posterior aspect of esophagus at the level of aorta arc, which was suggestive of double aortic arch or, less probably, aberrant right subclavian artery (Figure 1).
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EKG showing sinus rhythm with a rate of 78, T wave inversion in Lead 3 and V3.
Electrocardiogram (EKG) (Figure 1) showed sinus rhythm with a rate of 78, T wave inversion in Lead 3 and V3.
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CTPA showing bilateral subsegmental pulmonary embolism.
Due to the high suspicion of PE, computerized tomography pulmonary angiography (CTPA) (Figures 2 and 3) was done which revealed bilateral subsegmental pulmonary embolism.
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CTPA showing mild subsegmental pulmonary infarctions of the lower lobes.
Due to the high suspicion of PE, computerized tomography pulmonary angiography (CTPA) (Figures 2 and 3) was done which revealed bilateral subsegmental pulmonary embolism.
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Preoperative X-ray.
A standard emergency anteroposterior radiograph revealed an intertrochanteric fracture, severe deformity of the left hip joint, and the migrated implants used for the arthrodesis (Fig. 1).
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Preoperative CT-scan.
Computed tomography (CT) imaging of the left hip joint showed a displaced intertrochanteric fracture distal to the ankylosed hip joint, some artifacts due to the osteosynthesis material, and marked atrophy of the gluteus muscles (Fig. 2).
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Postoperative X-ray.
We decided to perform a surgery to remove the osteosynthesis material used for arthrodesis of the left hip and then perform the internal fixation using a locking plate and locked screws (Fig. 3).
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First brain MRI.. Note: Left occipital lobe lesion showed abnormal T1 hypointensities (A), T2 (B), and FLAIR (C) hyperintensities.. Abbreviation: FLAIR, flow attenuated inversion recovery.
T1 and T2 signals, and high signals on flow attenuated inversion recovery (FLAIR) sequence (Figure 1) as well as a slightly increased signal on diffusion weighted imaging (DWI). The brain magnetic resonance angiography was normal.
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Subsequent brain MRI.. Note: Lesions with abnormally high signals on FLAIR (A) and DWI (B) with poorly defined margins along the gyri in the left occipital-temporal lobe, which was slightly enhanced after gadolinium enhancement (C).. Abbreviations: DWI, diffusion weigh imaging; FLAIR, flow attenuated inversion recovery...
The patient underwent another MRI showing lesions with abnormally high signals on FLAIR and DWI with poorly defined margins along the gyri in the left occipital-temporal lobe, which was slightly enhanced after gadolinium enhancement (Figure 2).
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(a) Echo showed RV diameter 31.8 mm, the wall of the RV became thinner. (b) CMRI showed foci of fat in right ventricular free wall.
Echo showed the right ventricular (RV) was significantly dilated (RV diameter 31.8 mm), RVED/LVED = 0.67, the wall of the RV became thinner, interwoven reticular muscle fiber structure can be seen in the RV (Figure 1). Cardiac magnetic resonance imaging (CMRI-in local hospital) revealed a dilated right ventricular outf...
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Colonoscopic findings of compressible, blue nevi, approximately 5-10 mm in size.
Subsequent upper and lower endoscopy was done that revealed two 5 mm blue venous blebs in the esophagus and multiple patches of blue venous blebs throughout the colon (Figs. 1 and 2).
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On colonoscopy, numerous blue nevi are seen without any active bleeding.
Subsequent upper and lower endoscopy was done that revealed two 5 mm blue venous blebs in the esophagus and multiple patches of blue venous blebs throughout the colon (Figs. 1 and 2).
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(A) A midsagittal T1-weighted image of the spinal cord. (B) A midsagittal T2-weighted image of the spinal cord. There is no increase in the signal intensity on the spinal cord in T1 and T2 weighted image of the MRI. The MRI showed no signs of hematoma, abscess, or arachnoiditis.
The MRI showed no signs of hematoma, abscess, or arachnoiditis (Fig. 1).
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chest radiograph of the patient
ECG showed a sinus arrhythmia with slightly tall and tented T waves (Figure 1).
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Partially calcified mass with heterogeneous contrast enhancement on the fundal region and greater curvature of the stomach
CT study revealed a 12x10x9 cm partially calcified mass with heterogeneous contrast enhancement on the fundal region and greater curvature of the stomach (Figure 1).
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Specimen of resection
The patient underwent a total gastrectomy associated to a distal splenopancreatectomy and segmental transverse colectomy (Figure 2).
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CD117 expression in stromal gastric tumor (x 10)
The final pathologic diagnosis was collision tumor of gastric GIST and pancreatic adenocarcinoma (Figure 3, Figure 4).
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The architecture of the approach being used for the CPN construction.
A sub-network of Capecitabine visualized by Cytoscape in the CPN is shown at the right lower corner in Figure 1, where the edges in red indicate all associations with Capecitabine, and the green edges indicate DPYD and C18orf56 are linking to Capecitabine respectively.
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A sub-network of Capecitabine taken from the CPN. Blue solid lines indicate the direct association existed in the CPN, while the red dotted line indicates the indirect inference applied in this case study.
The zoomed out network is shown in Figure 3. The association between "Urinary Bladder Neoplasms" and "Capecitabine" could be inferred through multiple paths as shown in Figure 3.
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Clinical features of the patients with PIK3CD mutations. Patient 1 (A-C): CT scan reveals pulmonary nodules with cavity formation, and patchy infiltration (A, right lung), and maxillary sinusitis (B); Hematoxylin and eosin (HE) staining of renal biopsy showed no proliferation of capillary endothelial cells and mesangia...
CT also showed pulmonary nodules with cavity formation, and patchy infiltration, and bilateral maxillary sinus and ethmoid sinusitis ( Table 1 , Figures 1D, E ). Due to recurrent and refractory lung infections, she underwent bronchoscopy during hospitalization, showing mucosal nodule lymphoid hyperplasia in the entire...
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Immunohistochemical analyses for p110delta, CD3, and CD20. Compared with control (A, D), expression of p110delta (brown signal) in lung tissue and lymph node sections from patient 1 (B, E) and 2 (C, F) significantly increased. Many inflammatory cells infiltrated around the airway and in the lung parenchyma (H, I, K, L)...
Lung biopsy suggested inflammatory cells infiltration ( Figure 2 ) and absence of granulomatous lesions, and renal biopsy pathology indicated mild glomerular disease ( Figure 1F ). Immunohistochemical staining of p110delta, CD3, and CD20 were performed in biopsy tissues of both patients taken previously ( Figure 2 ). I...
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Clinical features of the patients with PIK3CD mutations. Patient 1 (A-C): CT scan reveals pulmonary nodules with cavity formation, and patchy infiltration (A, right lung), and maxillary sinusitis (B); Hematoxylin and eosin (HE) staining of renal biopsy showed no proliferation of capillary endothelial cells and mesangia...
CT also showed pulmonary nodules with cavity formation, and patchy infiltration, and bilateral maxillary sinus and ethmoid sinusitis ( Table 1 , Figures 1D, E ). Due to recurrent and refractory lung infections, she underwent bronchoscopy during hospitalization, showing mucosal nodule lymphoid hyperplasia in the entire...
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Immunohistochemical analyses for p110delta, CD3, and CD20. Compared with control (A, D), expression of p110delta (brown signal) in lung tissue and lymph node sections from patient 1 (B, E) and 2 (C, F) significantly increased. Many inflammatory cells infiltrated around the airway and in the lung parenchyma (H, I, K, L)...
Lung biopsy suggested inflammatory cells infiltration ( Figure 2 ) and absence of granulomatous lesions, and renal biopsy pathology indicated mild glomerular disease ( Figure 1F ). Immunohistochemical staining of p110delta, CD3, and CD20 were performed in biopsy tissues of both patients taken previously ( Figure 2 ). I...
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The room where simple and gastrointestinal series radiography was performed.
The working environment and the equipment he used are shown in Figures 1 and 2.
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The room where mammography and bone marrow density tests were performed.
The working environment and the equipment he used are shown in Figures 1 and 2.
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Ultra-wide field fluorescein angiography demonstrates peripheral telengectatic vessels, nonperfusion, and leakage in Coats disease. The patient subsequently underwent an EUA with targeted panretinal photocoagulation
A negative UWF-FA, meaning one without significant ischemia or leakage, can guide the decision to observe with serial examinations and photographs and eliminate the need for an exam under anesthesia as shown in Fig. 4.
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(a) CT scan showing a high contrast mass, but no axial lymph node swelling. Abnormal findings were observed in distant organs. (b) Contrast-enhanced MRI showing a mass in the same region that had early arterial enhancement and gradual washout.
The patient was admitted to our hospital with complaints of a mass in the right breast without axial lymph node swelling on computed tomography (CT) (Fig. 1a). Contrast-enhanced mic resonance imaging (MRI) showed a mass with early arterial enhancement and gradual washout measuring 9.3 x 5.8 x 10.7 mm (Fig. 1b).
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The tumor shows trabecular growth patterns with a rosette formation.
The final pathologic diagnosis was NECB with small polygonal cells having a small amount of cytoplasm, high nuclear-cytoplasmic ratio, and finely granular chromatin (Fig. 2).
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(a) CT reveals the presence of anterior mediastinal lymph node metastasis. (b) After chemotherapy, CT reveals no lymph node metastases.
Forty months after a right breast mastectomy, CT revealed anterior mediastinal lymph node recurrence (Fig. 3a). CT was performed after the chemotherapy and anterior mediastinal lymph node recurrence was not detected (Fig. 3b).
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Frontal radiograph showing multiple dense radio-opacities in the right upper quadrant of the abdomen, resembling well-formed limb bones and spine.
On imaging, a frontal radiograph of the abdomen showed multiple dense radio-opacities in the right upper quadrant of the abdomen resembling well-formed limb bones and spine (Figures 1, 2).
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Magnified view of the radiograph from Figure 1; Magnified view: blue arrow - limb bones; red arrow - spine; green arrow - pelvic bones.
On imaging, a frontal radiograph of the abdomen showed multiple dense radio-opacities in the right upper quadrant of the abdomen resembling well-formed limb bones and spine (Figures 1, 2).
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Sagittal multiplanar reformats of contrast-enhanced computed tomography of the abdomen. Blue arrows are showing. (A) Spine; (B) Rib; (C) Limb bone.
On contrast-enhanced computed tomography of the abdomen (Figures 3, 4) with a 3D-volume-rendering technique (Figure 5), a heterogenous, well-circumscribed soft tissue mass was noted in the right anterior pararenal space in a suprarenal location.
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Coronal multiplanar reformat of contrast-enhanced computed tomography of the abdomen. Blue arrow point to the ribs and red arrow to the spine.
On contrast-enhanced computed tomography of the abdomen (Figures 3, 4) with a 3D-volume-rendering technique (Figure 5), a heterogenous, well-circumscribed soft tissue mass was noted in the right anterior pararenal space in a suprarenal location.
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Volume rendered CT image showing Fetus in fetu.
On contrast-enhanced computed tomography of the abdomen (Figures 3, 4) with a 3D-volume-rendering technique (Figure 5), a heterogenous, well-circumscribed soft tissue mass was noted in the right anterior pararenal space in a suprarenal location.
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Microscopy of host cornea showing the presence of a thin but distinct Descemet's membrane (arrow). The specimen was stained with periodic acid-Schiff.
The graft was otherwise clear and this sheet was presumed to be retained DM, as confirmed on histopathology (Figure 1, arrow).
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In vivo confocal microscopy enables high resolution imaging of the cornea and conjunctiva. This image reveals a clear image of the corneal endothelium with healthy cell count and thickness of 502 microns.
This was diagnosed as retention of the host's DM rather than a detachment of the donor's DM (Figure 2) as the latter would have been associated with endothelial loss and corneal decompensation.
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Echocardiographic findings. Echocardiography performed at the age of 3 months shows (A) a normal ventricular wall thickness but (B) slightly accelerated blood flow in the right ventricular outflow tract. Echocardiography performed at 5 months of age shows (C) significant myocardial hypertrophy and (D) an obstructive pa...
Echocardiography showed normal ventricular wall thicknesses (Figure 2A). (interventricular septum (IVS) measured as 4.5 mm, Z score +1.62; left ventricular posterior wall (LVPW) measured as 4 mm, Z score +0.24) and slightly accelerated blood flow in the right ventricular outflow tract (Figure 2B). Standard conventional...
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Electrocardiography reveals a prolonged QTc interval.
An electrocardiogram revealed sinus rhythm and a prolonged QTc interval (Figure 4).
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file_0002072
PMC10076737_01
CC BY
PMC8605226_01_gr1.jpg
PMC8605226_gr1_undivided_1_1.webp
Chest X-Ray of a 3-months-old boy with Pre-XDR TB. It shows infiltrate at the upper-middle right lung field with an increased of bronchovascular marking.
The chest x-ray showed active tuberculosis with infiltrates at the right upper-middle lung field with an increased of bronchovascular marking (Fig. 1).
fig1
PMC8605226_01
PMC8605226
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PMC8605226_01
CC BY
PMC8605226_02_gr2.jpg
PMC8605226_gr2_undivided_1_1.webp
Chest X-Ray of a 14-years-olf girl with Pre-XDR TB. It shows opacity at the right hilar, lobulated infiltrate in the left apex, nodular at left hilar, and lymph node enlargement at bilateral peri-hilar.
The chest x-ray showed active tuberculosis with opacity at the right hilar, lobulated infiltrate in the left apex, nodular at left hilar, and enlarged bilateral peri-hilar lymph nodes (Fig. 2).
fig2
PMC8605226_02
PMC8605226
file_0127425
PMC8605226_02
CC BY
PMC8077606_01_cro-0014-0634-g02.jpg
PMC8077606_cro-0014-0634-g02_undivided_1_1.webp
PSA level over the course of the treatment.
F2
PMC8077606_01
PMC8077606
file_0116726
PMC8077606_01
CC BY-NC
PMC6472062_01_13006_2019_210_Fig1_HTML.jpg
PMC6472062_13006_2019_210_Fig1_HTML_undivided_1_1.webp
Antenatal: Right breast
The breasts and abdomen (antenatally) are shown in Fig. 1 (Antenatal: Right breast), Fig. 2 (Antenatal: Left breast) and Fig. 3 (Antenatal: Breasts and abdomen).
Fig1
PMC6472062_01
PMC6472062
file_0091987
PMC6472062_01
CC BY
PMC6472062_01_13006_2019_210_Fig3_HTML.jpg
PMC6472062_13006_2019_210_Fig3_HTML_undivided_1_1.webp
Antenatal: Breasts and abdomen
The breasts and abdomen (antenatally) are shown in Fig. 1 (Antenatal: Right breast), Fig. 2 (Antenatal: Left breast) and Fig. 3 (Antenatal: Breasts and abdomen).
Fig3
PMC6472062_01
PMC6472062
file_0091988
PMC6472062_01
CC BY
PMC6472062_01_13006_2019_210_Fig4_HTML.jpg
PMC6472062_13006_2019_210_Fig4_HTML_undivided_1_1.webp
Postnatal Day 6: Breasts
Fig4
PMC6472062_01
PMC6472062
file_0091989
PMC6472062_01
CC BY