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14872700
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Ann Arbor Skyline, Huron high schools collect 169 pounds of food at football game
Football and food are common companions. But at Friday’s Ann Arbor Huron versus Skyline football game, the emphasis was on donating not consuming.
Courtesy of Food Gatherers
The Skyline Football Parents Club organized the last-minute food drive war between the competing teams. It was Skyline’s homecoming game, and the Eagles staved off a second-half comeback by the Huron River Rats to win 41-34.
The Skyline Parents Club attempted to organize a similar food drive last year but wasn’t able to pull it off in time, said Mary Schlitt, director of development and marketing for Food Gatherers.
“We thought this would be a great opportunity for both local schools to get involved with a local organization and for the students to give back,” Michelle Traster, vice president of the Skyline Football Parents Club, said in an email.
Schlitt said the two high schools’ 169 pounds of food was a “fair amount” given the time frame the football programs were working within. Skyline’s parents hope this is just the first of an annual homecoming food drive.
Skyline High School collected 120 pounds of food, while Huron collected 49 pounds of food. Together, the schools filled a single large barrel.
According to its website, Food Gatherers distributed more than 5 million pounds of food throughout Washtenaw County last year. To donate or to organize a food drive, contact Food Gatherers at (734) 761-2796 or email firstname.lastname@example.org.
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http://www.annarbor.com/news/skyline-huron-high-schools-collect-169-pounds-of-food-at-fridays-football-game/?cmpid=RSS_link_news
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14872701
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I received this book for free from the publisher in exchange for an honest review. This does not affect my opinion of the book or the content of my review.Riveted by Jay Crownover
Series: Saints of Denver #3
Published by William Morrow Paperbacks on 14th Feb 2017
Genres: Contemporary, Romance
Source: the publisher
Buy on Amazon US, Buy on Amazon UK, Buy on Kobo, Buy on itunes, Buy on B&N
The next book in the smoking hot SAINTS OF DENVER series from NYT bestselling author of the MARKED MEN series, Jay Crownover
Everyone else in Dixie Carmichael’s life has made falling in love look easy, and now she is ready for her own chance at some of that happily ever after. Which means she’s done pining for the moody, silent former soldier who works with her at the bar that’s become her home away from home. Nope. No more chasing the hot as heck thundercloud of a man and no more waiting for Mr. Right to find her; she’s going hunting for him… even if she knows her heart is stuck on its stupid infatuation with Dash Churchill.
Denver has always been just a pit stop for Church on his way back to rural Mississippi. It was supposed to be simple, uneventful, but nothing could have prepared him for the bubbly, bouncy redhead with doe eyes and endless curves. Now he knows it’s time to get out of Denver, fast. For a man used to living in the shadows, the idea of spending his days in the sun is nothing short of terrifying.
When Dixie and Church find themselves caught up in a homecoming overshadowed with lies and danger, Dixie realizes that while falling in love is easy, loving takes a whole lot more work… especially when Mr. Right thinks he’s all wrong for you.
Riveted is about a woman who waited so long to find the right one and when the right one came along she wasn’t sure if she would ever be the right one for him. Dixie Carmichael has always believed in love, she has this bubbly happy personality and she wants everyone around her to be happy. Dashiel ‘Church’ Churchill is trying to recover himself before heading to his hometown, he is the silent brooding type.
Church and Dixie work together at the bar owned by Asa and Rome, in the months that Church has been there, Dixie has really taken with him. When Church has to return to him hometown and needs a favour, he ofcourse thinks of Dixie, the warm kind hearted woman he has gotten to care for more than he would like to admit.
Church and Dixie have both been through a lot, Church has been through several tragedies (from his parents to being in the military) that make him want to run away as far as he can from the word love. While Dixie even through the hardships she faced never gave up on love. Dixie’s gentle and sweet nature makes Church slowly but surely realise that not all love given ends up badly.
I really liked them together, its Jay Crownover so ofcourse the couple had abundance of chemistry and connection but more than I really liked how they were with each other. It was just gentle kind and caring love. It has opposites attract trope which worked really well here. We get to see them grown closer and get to know each other and fall deeper in love. They were honest and understanding towards each other. It was a natural progression of their relationship and while Church didn’t think that a road trip and being this close to Dixie would make him open up to her, and just end up being really in love with her (which was what he had hoped to avoid).
The book has a road trip, a homecoming, suspense and a couple who didn’t think they would get a happily ever after. I really adore this series, the characters are multifaceted, their personalities vivid and the secondary characters are also very interesting. A fantastic edition the series and I’m really looking forward to Poppy and Wheeler’s story!
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http://www.afortressofbooks.com/2017/02/14/review-riveted-jay-crownover/
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14872702
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Women’s basketball beats UMKC, still undefeated
The Eastern Michigan University women’s basketball team took on the University of Missouri-Kansas City Kangaroos, winning 75-66 in a “home game” at the Activities Center on the campus of Madonna University in Livonia, Mich.
The St. Joe’s Holiday Ball forced the Eagles to relocate, but they brought their game with them, improving to 6-0 on the season.
Despite shooting 9-37 from three-point range, EMU (6-0, 0-0 Mid-American Conference) was led by Janay Morton, who had a team-high 18 points.
Desyree Thomas had another big game as she scored 17 and dished out six assists. EMU also had a big lift from Jamaica Bucknor who added 11 points. Emu’s Olivia Fouty had eight points but lead EMU in rebounds with 10.
The game was scoreless for the first ninety seconds, until a fast break layup from Thomas from a Fouty defensive rebound.
UMKC (2-7, 0-0 Western Athletic Conference) got its first points of the game on Taylor Strickland’s layup that made it 4-2 in favor of EMU with 16:38 remaining in the first half.
After some turnovers from EMU, UMKC scored six straight points in a one-minute span to take a four-point lead.
Eastern fired back with a three pointer from Haley Moore to bring them within three. Consecutive three-point makes from Bucknor and Thomas gave them the lead.
UMKC would call for a timeout after Moore hit another three ball making it EMU’s fourth straight three-pointer to bring it to a 16-12.
Following a timeout from UMKC, the Eagles got hot from beyond the arc as Thomas with a pull up to hit her second triple of the game. Eastern would go on three-point shooting streak by hitting five in a row and Morton would score to give them a 21-16 lead.
The Kangaroos showed that they weren’t phased by EMU’s run, by make a couple of scores to bring them within two points. A Strickland shot would make it a tie game at 26-26 with six minutes remaining in the half, but a three from Morton would once again give EMU the lead. Both teams could not score for two minutes until Fouty hit two free-throws and EMU’s Denaya Brazzle would make her first basket to make it 34-26.
In the second half, EMU gained a 10-point lead, its largest lead of the game after Phillis Webb was fouled making a lay-up and made it a three-point play by knocking down a free throw and keep Eastern on top, 48-38.
EMU would eventually have a 70-66 lead later on in the second after Sara Stone would hit a free throw with 18 seconds left on the clock after a steal from Thomas would make it a 73-66 lead after hitting free throws on a UMKC foul.
EMU’s Natachia Watkins hit a couple of free throws for the nine-point win.
The Eagles’ next game will be against the University of Michigan, Wed. Dec. 11 at 7 p.m. at the Crisler Center in Ann Arbor.
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http://www.easternecho.com/article/2013/12/womens-basketball-beats-umkc-still-undefeated
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14872703
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Live at The Bassmnt, vowels optional.
TEXT AND PHOTOS BY MARK JACKSON
Fresh off of their Rock On The Range and Rocklahoma appearances, One Less Reason returned to their roots and played a homecoming show in Jackson, Tennessee, at the Bassmnt live venue. Although lead singer Cris Brown has called Memphis home for some time now, he hails from Jackson and that’s where his first band Lap Dog was born. The band Lap Dog didn’t start out as expected as their first gig was a night club in Jackson called Spinakers that allowed them to play on the outside patio. Halfway through the band’s set the manager actually paid them one hundred dollars to stop playing and load up.
If you have heard One Less Reason in the last twelve years then you already know they have defiantly gotten better. The nine albums since forming One less Reason has had several member changes along the way, but the constant has been Cris’s vocals and writing. With a controlled soulful voice that can go from soft heart touching all the way up to screaming rock that will have you jumping in the aisle.
One Less Reason’s first radio hit was back in 2005 with the single “Favorite Color” and have had a great underground follow ever since. With the release of The Memories Uninvited in 2016 the band has scored yet another hit with “Break Me” and even toured with Sick Puppies before landing not one but two Festival spots so far this year. The current line up seems to have come together as a whole firing on all cylinders and every member has mastered their instrument with the best stage presence to date.
Cris had a surprise in store for the hometown crowd and brought out ex guitarist Jerry Bailey for a couple acoustic songs, it was a great and touching moment for those of us who have been long time fans. Another highlight of the evening for me was when OLR played the song “uneasy”. Cris announced this was the first time he had played the song live. Cris brought up Anne Cline, an up and coming artist with his record label Tattoo Millionaire Records, to sing the female part originally sang by Blair Simpson.
If you are tired of the trend of the screaming heavy metal or the rap/rock acts that start to sound like one another, I encourage you to download some of the One Less Reason albums and make rock great again.
To see and follow more of Mark’s concert pictures follow @markjacksonphotography1
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http://blurtonline.com/review/one-less-reason-61717-jackson-tn/
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14872704
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Nestled along the shores of the Grand River and home to over 17,000 residents, Grandville has become known as ‘the city of churches and parks.’ With streets graced by numerous beautiful churches and green spaces, citizens have plenty of options for recreation and leisure.
All-American lifestyles flourish in Grandville with stable, affordable neighborhoods, pedestrian-friendly districts and a strong sense of community. Despite being located in the heart of bustling West Michigan, the communities retain small-town appeal. Residents enjoy a multitude of parks, top-rated schools, a premier regional shopping destination and median incomes exceeding regional, state and national rates.
Major roadways like M-6, U.S. 131 and I-196 provide easy commutes and open employment options for residents, linking them to all the cultural and shopping amenities the Grand Rapids area offers. The area is within minutes of some of Lake Michigan's most beautiful golden sand beaches and world-class Great Lakes activities.
Whether you are looking for a luxury condo in Rivertown Park, an affordable first home, or a lakefront cottage, Grandville’s hometown package is hard to resist.
Thinking about buying or selling a home, condo or townhouse in Grandville? Let Grandville real estate agent Shannon Benton help you discover all your options. Contact Shannon here or call her directly at 616.340.2940. The first step is just a phone call away!
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http://shannonbenton.com/grandville-michigan-mi.php
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14872705
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An Anchor Handling Tug (AHT) with a 100 tonnes winch, a 140 TM crane and a 48 tonnes bollard pull. Coastal Voyager (2012) is of the type Shoalbuster. The unrestricted trading area and the available moon pool makes Coastal Voyager a very versatile tug. This Tug operates in shallow and deep waters and has been active in the Dredging & Marine Construction, Oil & Gas, and Offshore Wind industry.
Draft: 3,20 m
Power output: 2462 kW / 3344 hp
Propulsion: Twin fixed pitch propellers in nozzles & one bow thruster
Bollard Pull: max 50 ton
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http://www.actamarine.com/en/vessels/7/Coastal-Voyager
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14872706
|
Cold Forming Machine Operator Jobs
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3 weeks ago
Cold Form Operator I - 1st Shift (064, 065, 066) Job Description Job Summary & Essential Functions: The following describes in general terms the purpose and scope of the position. Duties may include the basic set up and operation of various machines, hand...
Overview: We are currently seeking a PET Injection Mold Machine Operator for our Sherman Facility. We are the National Leader in a Stable, Growing Industry! We are a leading provider of top quality rigid packaging. Our organization consists of more than 2...
3 weeks ago
Business Job Title: Fabrication Operator Job Summary: The Fabrication Operator is responsible for the setup, adjustment and operation of all progressive tooling in all sizes of Punch Presses. Daily use of Servo feeder, straightener, and dereeler and famil...
926 West State Street
Job ID: 117415 Amcor Masonry Products is a division of the Oldcastle Architectural Products Group (APG). APG is North America’s leading manufacturer and supplier of concrete masonry, dry mix, and hardscape products. With over $2B in sales, APG operates ac...
North Salt Lake, UT
Full-Time | Pay: $15.00 - $30.00/hour
JMJ Talent Solutions and Staffing is hiring for a CNC/Lathe Operator for our client in Alsip, IL. Our client specializes in contract manufacturer of precision machined parts and assemblies. With core competencies in CNC Milling and CNC Turning, they focus...
JMJ Talent Solutions
2646 Highway Avenue
Job ID: 118146 Chard Tiling & Excavating, an Oldcastle Materials Company, was established in 1976 in Belle Plaine, Minnesota. With over 30 years in the contracting business, we have grown to serve clients in many industries. We have provided services to n...
Belle Plaine, MN
Full-Time | Pay: $13.42 - $14.17/hour
A nationwide manufacturer located in Seguin, TX is currently seeking Production Technicians to join their team! Job Duties: Follow all plant safety procedures and use all applicable personal protective equipment (PPE). Hold other team members accountable...
New Braunfels, TX
Are you an energetic and dependable employee that takes pride in your craft? Would you like to be part of a dynamic and growing aerospace manufacturing business in Savannah, GA? Arconic Forgings and Extrusions (AFE) is looking for qualified Forge Operator...
Meridian Specialty Yarn Group, Inc. (MSYG) PRIMARY FUNCTION: ● Under the direction of plant management, this position performs all aspects of packaging and winding to assist with the production of the highest quality product at the lowest possible cost, i...
40 Rex Avenue
Overview: Advanced Drainage Systems (ADS) is the leading manufacturer of high performance thermoplastic corrugated pipe, providing a comprehensive suite of innovative water management products and drainage solutions. ADS operates a global network of 61 ma...
TrinityRail OEM is searching for a talented team player to fill the open position of Equipment Operator 2 (Career Level) in our Saginaw, TX railcar manufacturing plant 8192! Sets up and operates machines; may utilize blueprints, makes adjustments for mate...
Full-Time | Pay: $13.50 - $14.20/hour
Sets up and operates mechanical, hydraulic, or pneumatic heavyduty power presses to bend, form, pierce, cut, and stamp sheet metal intoshapes, forgings or weldments by performing the following duties. Essential Duties and Responsibilities includethe fo...
5271 Plainfield Avenue Northeast
Grand Rapids, MI
Full-Time | Pay: $10.00 - $18.00/hour
Position Summary Sets up and operates engine lathes to perform machining operations such as turning, boring, threading and facing on metal or nonmetallic workpieces according to specifications. Essential Duties and Responsibilities Reasonable accommodatio...
North American Pipe Corporation Job Description SUMMARY Responsible for all operations involved in making couplings for pipe. ESSENTIAL DUTIES AND RESPONSIBILITIES Adhere to all safety polices and procedures; perform tasks in a safe manner. Position perso...
Flex-N-Gate is a leading manufacturer and supplier of components for the automotive industry, recently ranked 10 th of the 150 Top North American Suppliers in “Automotive News.” A growing and vital company, Flex-N-Gate provides a great opportunity for har...
Full-Time | Pay: $12.50 - $13.25/hour
Our client is looking for people who are motivated and who have a drive for customer service. This is a smaller locally owned business that is growing rapidly and they are looking to add about 5-10 associates in their packaging department. This client con...
Essential Functions: Sets-up and operates cold heading and rolling machines to form raw material (typically carbon steel, stainless steel, and aluminum in wire or rod shape) into fastener collars and pins. Operations performed by machine are normally pack...
Department: Maintenance Reports To: Maintenance Manager FLSA Status: Non-Exempt Updated: 7/13 SUMMARY The Industrial Maintenance Mechanic will perform diagnostics and repairs regarding mechanical aspects of machines and equipment. Must be able to disassem...
MAINTENANCE ELECTRICAL SPECIALIST Department: Maintenance Reports To: Maintenance Manager FLSA Status: Non-Exempt Updated: 3/16 SUMMARY The Maintenance Electrical Specialist’s primary responsibility is to maintain, upgrade, and repair existing electrical...
SUMMARY: Position exists to run/feed material to or from a machine or conveyor system by performing the following duties. ESSENTIAL DUTIES AND RESPONSIBILITIES include the following: Pick up materials from pallet, hand truck, etc. and place items onto c...
Position Role Job Title: Line Worker Level 2 Department: Production Reports To: BPO/Supervisor FLSA Status: Hourly-nonexempt Prepared By: jlc Prepared Date: 7/2000 Reviewed Date: 9/7/2010 SUMMARY: Position exists to run/feed material to or from a machine...
Overview: We are currently seeking a Production Line Technician (3rd shift) for our Santa Ana, CA facility. Will report directly to * Shift Supervisor *. We are the National Leader in a Stable, Growing Industry! We are a leading provider of top quality ri...
Santa Ana, CA
Full-Time | Pay: $48.04/hour
PRIDE Industries is a fast-paced company with a mission: To Create Jobs for People with Disabilities while providing high quality, value-added solutions to our nationwide customers. POSITION SUMMARY: Under general supervision, the Electrician (Inside Wire...
Arconicis the world’s leading producer of primary aluminum, fabricated aluminum and alumina. In addition to inventing the modern-day aluminum industry, Arconic innovation has been behind major milestones in the aerospace, automotive, packaging, building a...
Job ID: 118197 Come join Dolomite Products Co., Inc. and begin the rest of your future with us. Dolomite’s recruiting Vision Statement is to provide a World Class development program that attracts, retains, and produces emerging leaders within Dolomite an...
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http://www.careerbuilder.com/jobs-cold-forming-machine-operator?pay=0&siteid=cbnsv&emp=ALL&posted=30
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14872707
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Consider the remedies under the rubric:
MIND - DELUSIONS - superiority, of ...
astat. aur. aur-m. aur-s. bar-br. bar-i. bar-met. bism-sn. caes-met. cinnb. crot-c. germ-met. granit-m. hafn-met. irid-met. Kola lanth-met. merc. merc-d. musca-d. osm-met. Plat. plb. plb-m. plb-p. polon-met. polys. rhen-met. tant-met. thal-met. tung-met.
Notice how many from the list can be mapped onto Row Six, of the periodic table - the Gold Series.
- Cs: caes-met.
- Ba: bar-br. bar-i. bar-met.
- La: lanth-met.
- Hf: hafn-met.
- Ta: tant-met.
- W: tung-met.
- Re: rhen-met.
- Os: osm-met.
- Ir: irid-met.
- Pt: Plat.
- Au: aur. aur-m. aur-s.
- Hg: merc. merc-d.
- Th: thal-met.
- Pb: plb. plb-m. plb-p.
- Bi: bism-sn.
- Po: polon-met.
- At: astat.
- Rn: Radon.
We all try to face the world, to assert ourselves and take on some sort of responsibility. The Gold Series, in Homeopathy is associated with the Brow Chakra, and the Universal Consciousness of the vMeme, which implies maturity, power and influence in the world.
The stages to the left side of the Periodic Table, as everyone knows have an incomplete outer orbital. This can be condisered a deficiency. The elements at the middle stages of the series are relatively stable, and the elements at the extreem right have excessive energy in the outer shell.
This is reflected in the behaviour of the Homeopathic Remedies in this series - they are all into responsibility in some way - afraid of it (Baryata), demanding it (Aurum), abusing it (Merc), or loosing it (Plumbum)!
Interesting to note however, that the same group of people can be found under the rubrics for fear of being murdered (and anthrophobia) . Perhaps those who persue responsibility and power keenly fear its erosion?
In terms of Karen Horney's coping strateges the Gold Series may represent a neurotic striving for power (which can have elements of anxiety and inferiority) ... they need to be right all the time, to be recognised and admired, and ultimately to exploit or control others. The tendency to move against people is stronger than the need to move towards people.
Refs: Synthesis. Homeopathy and the Elements.
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http://structuralhomeopathy.blogspot.com/2009/01/relationship-of-homeopathic-remedies.html
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14872708
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Cadel Evans Extends Contract with Team BMC Racing
Earlier today Team BMC Racing announced that its Tour de France champion Cadel Evans has extended his contract with the team through the 2014 season. George Hincapie has also extended his contract.
Earlier today Team BMC Racing announced that its Tour de France champion Cadel Evans has extended his contract with the team through the 2014 season.
In addition to Evans, three-time U.S. national road champion George Hincapie has also extended his contract with the BMC Racing Team for through the 2012 season.
"Having these two stay with the BMC Racing Team next year allows for our continued growth by having our two captains stay on board to provide leadership and mentoring to others in our organization," Team BMC Racing President and General Manager Jim Ochowicz said.
"In George's case, we need him to help the young guys like Taylor Phinney and Greg Van Avermaet keep developing. For everyone else, he creates leadership in the classics and at the Tour de France."
After joining the BMC Racing Team as the reigning world road champion in 2010, Evans helped the squad earn its first berths in the Tour de France and Giro d'Italia the same season. This year, Evans is number one in the UCI WorldTour rankings and helping lead the BMC Racing Team to a position as number two in the team classification.
"I feel that as a team, we have grown successfully together," Evans said about his contract extension and added "It's been an enjoyable and satisfying journey so far. From the start, I have always felt the BMC Racing Team has had a lot of confidence in me as a member and often as a leader of the team. So a longer term contract echoes this. I look forward to the years ahead. We will keep working and progressing toward the future."
George Hincapie is excited about looking forward to his 19th season in pro cycling. Hincapie has been on the Tour team of Tour de France winners a total of nine times. Showing no sign of fading, in May, he was within a tire width of winning his fourth U.S. national road title. The 2012 season will be his 19th after turning professional in 1994.
"I'm really excited to continue the success of the team," Hincapie commented and added "My two years with the BMC Racing Team has been even better than my expectations. Being able to help Cadel win the Tour de France was a career highlight for me. To be able to continue on for another year offers me more opportunities to extend the goodwill of the team."
A team representative also told Roadcycling.com and Roadcycling.mobi that the team expects to announce several rider extensions and interesting new acquisitions in the coming weeks.
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http://www.roadcycling.com/Cadel-Evans-Extends-Contract-with-Team-BMC-Racing
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14872709
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Today marks the 12th anniversary of Jem and I being a couple. We met when we were 13 on a Scout camp site near Southampton and immediately became pen-pals. We wrote each other frequently, meeting up when we could, and soon fell in love. That love, despite being the painfully intense all-encompassing love of teenagers, has matured, strengthened and grown over time. We’ve now been married for over 3 years and our son Xander is 16 months old.
I want to take this opportunity to thank my wife for everything. Her constant loving support helps me in every aspect of my life from fatherhood to business to helping me deal with my health problems. I honestly don’t know what I would do without her.
❤ Thank You, Jem ❤
You’re the most wonderful woman I know - beautiful, funny, clever, loving, honest, understanding and a fantastic wife and mother. Every day I feel grateful to have you in my life and I truly hope I make you feel loved and appreciated. Together we make a brilliant team - the future never scares me, because I know whatever happens you’ll be there, by my side.
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http://www.benjiegillam.com/2012/02/12-years-together/
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14872710
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Pathological Validation of Functional Imaging in Head and Neck Squamous Cell Carcinoma. A Prospective, Non-commercial and Mono-centric Study
1. BACKGROUND AND SETTING
Concurrent (chemo-) radiotherapy (CRT) is the current standard of care for patients
with locally advanced head and neck squamous cell carcinoma (HNSCC). The proximity of
important functional structures with the tumour makes treatment however highly complex.
Treatment related toxicity can be severe with xerostomia and dysphagia gravely
complicating the patient's quality of life. The use of altered fractionation schedules
and/or concurrent chemotherapy has resulted in substantial gains in loco-regional
control, leading to significant improvements in overall survival. Although the
prognosis of patients treated with RT for locally advanced HNSCC is continually
improving, there are still a high number of locoregional failures.
Using highly conformal radiotherapy the investigators can increase the therapeutic
index by giving higher doses to the more radio-resistant parts of the tumour while
maintaining or even reducing dose to the surrounding tissues. Functional imaging can
help us to define these radio-resistant subvolumes and help us to delineate the gross
tumour volume (GTV) better in the future. Positron emission tomography (PET), Diffusion
weighted magnetic resonance imaging (DWI) and Dynamic contrast enhanced MRI (DCE-MRI)
can give us further insight in the tumour's underlaying biological and microstructural
characteristics. However, at the moment the investigators are not sure how to interpret
the different imaging parameters obtained from these functional imaging modalities.
Therefore, the investigators want to correlate the imaging parameters with the
pathological characteristics of the tumour. On the other hand the investigators want
to correlate the GTV defined on the functional imaging modalities with the pathological
GTV, and see if these modalities can help us to delineate the GTV more accurately in
1.2. IMAGING MODALITIES
1.2.1. FDG-Positron Emission Tomography (FDG-PET)
Increased glucose metabolism is a fundamental characteristic of many malignant tumours,
including HNSCC. Positron emission tomography (PET) after injection of radioactively
labeled 2' fluorodeoxyglucose (18F-FDG) can help us measure and quantify this
metabolism in tumours, using the standardized uptake value (SUV). Several studies have
correlated high SUV prior to treatment with significantly worse outcome in HNSCC.
Furthermore it appears that most local recurrences occur within the FDG-PET defined
GTV. The molecular base for this is not completely understood.
Proliferating tumour cells consume glucose at a high rate and release lactate and not
CO2. This way they omit the mitochondria driven oxidative phosphorylation of glucose
from the production of ATP (=Warburg-effect). Several molecular parameters have been
associated with this glycolytic switch, such as activation of the hypoxia induced HIF1α
and the increased presence of GLUT glucose transport proteins. So far no clear
correlation was found between the presence of hypoxia and FDG-uptake.
1.2.2. Diffusion-weighted Magnetic resonance imaging (DWI)
Diffusion weighted magnetic resonance imaging (DWI) can characterize tissues based on
the random displacement of water molecules. In biological tissues this displacement is
limited by underlying tissue-specific barriers and this difference can be quantified
and visualized using apparent diffusion coefficient (ADC) values. A study on 165
patients in our centre with HNSCC demonstrated that the pre-treatment ADC value is a
strong and independent prognostic factor for outcome. Patients with a high ADC value
respond worse to ionizing radiation than patients with a lower ADC value. There is
currently no clear explanation why tumours with a higher cellular density are more
radiosensitive than tumours with a low density. A number of microscopic features effect
water diffusivity in tissue (presence of necrosis, cellular density, inflammation,
integrity of cellular membranes). Many of these also affect the radio- and
chemosensitivity of the tumours.
1.2.3. Dynamic contrast enhanced Magnetic resonance imaging (DCE-MRI)
Dynamic contrast enhanced MRI (DCE-MRI) is a non-invasive imaging modality which has
been developed and evaluated for the characterization of vascular properties of
tissues. Adequate oxygen supply is essential for the effectivity if ionizing
radiation. However tumor angiogenesis is far from perfect and newly formed vessels
display permeability, tortuosity and a generally poor functionality. These vascular
properties could provide us insight in the aggressiveness and radiosensitivity of the
tumor. Dynamic computed tomography (CT) has demonstrated that perfusion measurements
can predict outcome in head and neck cancer after radiotherapy. Similarly quantitative
assessment of DCE-MRI has also been correlated with response to ionizing radiation in
patients with HNSCC. A recent trial on a limited number of patients correlated certain
DCE-MRI parameters with intratumoural hypoxia. However, so far no spatial correlation
has been done.
2. STUDY OBJECTIVES
2.1. PRIMARY OBJECTIVES
The main objective of this study is to correlate DWI, DCE-MRI and FDG-PET with the
spatial distribution of hypoxia in patients with head and neck cancer.
2.2. SECONDARY OBJECTIVES
A. To correlate findings on functional imaging with intrinsic molecular parameters
depicting proliferation, hypoxia and glucose metabolism.
B. To validate the use of the hypoxia markers and the 15-gene hypoxia gene expression
C. To compare tumour volume as derived from pathology with the volumes delineated on
the several anatomical and functional imaging modalities.
3. STUDY DESIGN
The target group for this trial is patients with a histologically proven squamous cell
carcinoma of the larynx, eligible for surgery, staged T3-4. Prior to treatment patients
will undergo an FDG-PET/CT and MRI with DW and DCE, dedicated for optimal visualization
of the primary tumor and analysis. The imaging modalities will be performed as close
to the surgery as possible (PET/CT one week before surgery; MRI one day before
Prior to treatment, three slices on the imaging modalities will be selected by a
radiologist based on their visual quality and heterogeneity of functional parameters.
These regions of interest will be compared to different histopathological parameters on
the resection specimen. The radiologist will also select regions, based on DWI and DCE
parameters, who are suspect to be hypoxic. From these regions a biopsy will be taken.
After total laryngectomy, the resection specimen will be oriented, and biopsy material
will be obtained from the regions in the tumour that have been selected on the imaging
modalities The rest of the specimen will be fixed in formaldehyde. To account for the
shrinkage of the tumour due to fixation, the resection specimen will be placed in a
cardboard box with an agarose solution and scanned with an MRI with T1w/T2 images. From
this a shrinkage factor will be calculated comparing the delineated T1 and T2 weighted
After fixation the tumour will be cut up into macroslices with a thickness of about
5mm. On each macroslice tumour volume will be delineated. Using this, the pathological
tumour volume will be determined taking into account the previously determined
shrinkage factor. This pathological volume will be compared to the tumour volume
delineated on the imaging modalities. On the different pre-surgery functional imaging
modalities, 4 separate observers will delineate the GTV. The different volumes will be
compared and overlap will be calculated after 3D specimen reconstruction and
The GTV obtained from the functional imaging will be correlated with the pathological
tumor volume of the resection specimen. This information will give us more insight into
the true power of the investigated functional imaging techniques in determining tumour
volume. This is important to assess the role of functional imaging modalities in
treatment planning in the future.
At the three levels, chosen by the radiologist on the imaging modalities, 4µm thick
slices will be taken. On each level an immunohistochemical staining will be carried out
(GLUT-1, CA-IX, HIF-1α, VEGF and KI 67 staining will be performed ).
IHC will be scored according to a semiquantitative scoring system using a field
analysis where each field will be assigend a score of 1-4 according to the approximate
area of immunostaining (0:0%, 1:1-5%, 2: 5-15%, 3: 15-30% and 4: >30%.
4. SAMPLE SIZE Twenty patients with squamous cell carcinoma of the larynx, planned to
undergo total laryngectomy, will be included.
Intervention Model: Single Group Assignment, Masking: Open Label
Correlation of functional imaging with tumor hypoxia.
The correlation of DWI, DCE-MRI and FDG-PET with the spatial distribution of hypoxia in patients with head and neck cancer.
2 years after start of the study.
Sandra Nuyts, PhD MD
University Hospitals Leuven
Belgium: Federal Agency for Medicines and Health Products, FAMHP
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http://www.knowcancer.com/cancer-trials/NCT01827709/
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14872711
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NEW YORK (AP) - Tim McGraw and the Black Eyed Peas are scheduled
to perform before the NFL season opener.
The NFL announced the musical artists Wednesday for the game between the Super Bowl champion Steelers and the Tennessee Titans
in Pittsburgh on Thursday, Sept. 10.
McGraw and Black Eyed Peas, both three-time Grammy winners, will
hold a free concert open to the public at Point State Park.
Natasha Bedingfield, Keith Urban and Usher performed before last year's opener in New York.
EA Sports sponsors the event.
(Copyright 2009 by The Associated Press. All Rights Reserved.)
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http://www.wtvy.com/sports/headlines/53070097.html
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One of the nation's top players that remains undecided on his college destination is Sulphur Springs (TX) quarterback Tyrik Rollison. A Rivals 100 member and ranked 41st in the latest ranking, Rol...
Subscribe today to read the full article and get everything Rivals has to offer.
- Member-only message boards
- Exclusive highlights and recruiting interviews
- Exclusive coverage of Rivals Camp Series
- Breaking recruiting news
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https://tcu.rivals.com/news/tcu-an-option-for-rollison
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14872713
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I don't know why this came as such a surprise. I've read of cases of mothers giving birth to medically fragile babies and being advised to institutionalize them as late as 1990. For some reason, though, the thought never occurred to me, when thinking about my own birth and infancy.
According to Grandma, "We didn't know the first thing about raising disabled babies. We didn't know anyone who had done it, and there wasn't the internet like there is today, to connect with other families. But we wanted you. We wanted to raise you and have you at home with us. So we figured it out. Your mom and I figured out how to clean your trach. Your mom went to every physical therapy appointment with you and learned what was reasonable to expect for you to be able to do and what wasn't."
|[Image is: Me and my sis, around age 2. We are on a hardwood floor, wearing yellow sundresses and pigtails. We are petting our grandma's cat, Miss Kitty.]|
I often think about this when I interact with parents who have kids with disabilities. There remains such a tremendous gap between us. I have spent a lot of time wondering why this is. My friend and fellow blogger, Ellen Stumbo articulates it like this: "You guys are the first generation raised out of institutions. Before that, parents always spoke for you. We had to. There was no other choice. Now, though, you've grown up, and you speak for yourselves. You're the first to ever do that. I don't think we, as parents, are used to it yet."
When I posed this to my grandma, she also added, "We spoke for you...and we did your thinking for you, too!"
I've never heard it put quite like that before, but I think it makes a lot of sense. It must be difficult for parents now to step back when their children (or adults in their child's community) speak up about something. Parents, grandparents, aunts and uncles...I have known all of them to be particularly fierce in their love and protection of me and my sister. We needed it. We need them.
Even when we are grown up, we never stop needing our parents and other adults in the family - but the way we need you sometimes changes.
WE NEED YOU TO KNOW WE ARE ON YOUR SIDE:
It makes sense you are on the defensive. It makes sense because you are used to fighting for us to have everything we need, want and deserve. You fought through exhaustion and sleeplessness. You learned to demand things. You learned, though you could not fight every single battle, to win the ones you knew were worth fighting.
As an adult in your child's community, we have been where your child is right now. We know how to articulate what they are too little to share. Big feelings they may not have words for until they are grown up. So when we speak up, know we are doing it for your child. We are on the same team you are. We want what's best for your child, too.
WE NEED YOU TO BACK US UP:
When we say something is harmful to our community, we are not saying it to hurt your feelings. We are saying it because it actually harms us. Trust that adults in your child's community have walked (and rolled) where your child has. And if we speak up about damaging portrayals in media, or ableism in everyday life, back us up. Parents and family members love and support us every day, and that is awesome. Know that boosting our voices about issues that directly impact us is the most amazing way to express that love and support.
WE NEED TO FEEL NEEDED:
I can't think of anything more powerful that a child with a disability can see, than their parents or family members making friends with adults with their same disability. Kids need role models. They need to know there are people like them who grow up and are happy. They need them to know their disability gives them identity and community and a place to belong. That it is not just something that makes them different.
We are so used to needing people and asking for help. It's so amazing to be able to help someone else. So, Mom, Dad, or Grandma, if you have a question about how to deal with your child's hurt feelings about being left out, or if you need a suggestion about how your child can best carry money with them using a wheelchair, or how to address self-esteem issues, talk to us. We want to help. And we may have some really helpful suggestions...
We come from different places. You know trauma relating to our disability (such as a diagnosis day) that those of us who have not known any different never experienced.
We know difficulty around public perception and attitudes around our disability. We struggle to integrate our identity as disabled people into our personhood, while surrounded by voices who tell us disability is not a good thing. That we should ignore it. Not speak of it. Use different language...when all of those things are ours to choose.
But we all want the same thing, essentially:
We want your children to grow up knowing they are loved and respected.
We are here, parents.
And we still need you.
Don't forget to connect on Facebook
|
https://toniasays.blogspot.com/2016/05/lets-talk-about-gap-between-disabled.html
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A popular argument in the resuscitation world is the adage that compression-only CPR saves more lives. While not all emergency providers may agree with this statement, the case for compression-only Cardio pulmonary resuscitation is quite strong.
So, What is Compression-Only CPR?
Rick Caissie, National Director, First Aid, Swimming & Water Safety explains, “Compression-only CPR is giving continuous chest compressions of approximately 100 compressions per minute, without giving rescue breaths,”
What Kind of Situations would this Technique Apply Best to ?
In most situations, the victim is surrounded by untrained or unwilling people around him. Administering CPR can be a huge task for those who are untrained in it. It isn’t just about going out there to help someone, it is about having the courage to perform what’s required in the most practical manner possible.
For an untrained person, giving rescue breaths may not just be a daunting task, there is also a certain amount of wariness involved when you have to give mouth-to-mouth to a stranger.
In light of this, a compression-only CPR may be the best option yet for such situations.
How does the Compression-Only Method of CPR Work?
The compression-only method involves 3 major steps:
- Look for signs of response. You might want to tap the victim or try talking to them to see if they’re conscious
- Call for help – Whether you’re a trained rescuer or not, always make sure you or someone on the scene calls the nearest emergency center to send an ambulance and medical rescue equipment
- Start compressions – Place one hand on the patient’s chest, place the other palm over this, lock your elbows and perform quick compressions at a rate of about 100 a minute
- Continue compressions till an AED or emergency help arrives
- If there are other volunteers on the scene, alternate giving compressions with them
The purpose of performing these compressions in case of a cardiac arrest on an adult patient is to keep blood flowing to the heart and the brain and other major organs, in order to prevent multiple organ failure.
Compressing the chest at a steady rate and a depth of 2-5 cms helps follow the pumping motion required for this function.
The compression-only method must not be followed if the victim is suspected of choking or drowning.
Why is Compression-Only Cardio Pulmonary Resuscitation Effective?
In case of cardiac arrest victims, especially in situations occurring outside of hospitals, it can be difficult for an untrained rescuer to remember or learn and execute all the steps of the traditional CPR method even if he/she has access to it.
The compression-only method is easy to remember and consists of simple steps which anyone, absolutely anyone can follow without the stigmas or fears associated with mouth-to-mouth resuscitation.
Another reason why compression-only CPR is so popular is because, one doesn’t need to stop compressions to perform rescue breaths, thereby pausing blood flow.
There might be a lot of debate surrounding the correct form of CPR to be followed in victims. While drowning victims might still need rescue breaths, a majority of cardiac arrest victims (adults) have shown a better survival rate in most cases as reported by hospitals.
What method of CPR would you prefer if you had to rescue someone?
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http://www.cprcertificationonlinehq.com/compression-cpr-choose-method/
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Believe or not, I was hesitant to post this at first because it wasn’t about BLACK CINEMA, but then I realized, why not? As if that has stopped me before. And what’s wrong with some positivity?
Of course there will be some holier than thous with a stick up their you-know-whats bitching and moaning that it’s not about BLACK CINEMA. It’s not. But it’s definitely all about black imagery in the media, which is what S & A is all about anyway.
So, in case you haven’t seen it, or want to see it again, here’s the First Lady, Michelle Obama, and two time Olympic Gold medalist Gabby Douglas, on The Tonight Show from Monday night.
And I have to admit, I’m still so impressed with what a remarkable, intelligent, confident and posed woman she is.
And Michelle ain’t bad either.
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http://www.indiewire.com/2012/08/watch-michelle-obama-and-gabby-douglas-together-on-the-tonight-show-142889/
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Category: Poetry & Drama|
The author of the book: St John Perse
Format files: PDF, EPUB
The size of the: 168 KB
Edition: HARVEST BOOKS
Date of issue: 21 October 1970
Description of the book "Anabasis":This internationally famous poem by the 1960 Nobel laureate was introduced to English-language readers in this translation by T. S. Eliot. In this definitive edition, French and English texts appear on facing pages. Preface by T. S. Eliot.
Reviews of the AnabasisUp to now regarding the guide we have now Anabasis suggestions people never have yet still left the writeup on the action, you aren't see clearly but. However, should you have currently see this guide and you really are ready to make the findings convincingly have you spend your time to depart a review on our site (we can easily post the two positive and negative testimonials). Put simply, "freedom regarding speech" All of us completely helped. Your own responses to lease Anabasis -- various other viewers is able to determine of a e-book. Such assistance can make us far more United!
St John PerseSad to say, at the moment we don't possess information regarding the actual performer St John Perse. On the other hand, we'd appreciate in case you have virtually any info on this, and are also able to provide the item. Send out it to all of us! We have the many examine, of course, if every piece of information are usually correct, we are going to publish on the internet site. It is vital for us that accurate concerning St John Perse. All of us appreciate it upfront if you are ready to visit fulfill people!
Download EBOOK Anabasis for free
|
http://clearwalksoft.com/poetry-drama/8742-anabasis.html
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Roberto Martinez claims Everton do not have to sell Leighton Baines or Ross Barkley in January.
Martinez has assured Evertonians neither player will be going next month, claiming the club's finances mean no-one needs to be sacrificed.
When asked about Barkley, the Blues boss joked: "We would not let anyone go out on loan in January!"
On a more serious note, Martinez claimed Everton are strong enough to resist any bids in January.
"Yes, absolutely," he said. "There's not even a doubt about it.
"I have said many times, in football you can't fight the trends of the game, but what you can do as a football club is dictate the timing.
"Everything you do should be for the good of the football club. We've done that before and everything that happens should be to improve the squad and improve the blend and youth of the squad. I can guarantee that will be the case 100 per cent in January."
Martinez claims he does not need to worry about any possible bids from United because he knows Everton do not have to accept them.
"No, not when we are in a strong position financially," he said. "As a football club, when you're in a position where you have to bring money in, then it can be a real difficult position.
"You can be a little bit anxious, a little bit frustrated because when you need to make financial decisions, the squad is not going to benefit from them.
"When you make football decisions, then you are in a stronger position."
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http://www.irishmirror.ie/sport/soccer/transfer-news/leighton-baines-manchester-united-transfer-2975026
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Martha Stewart Living makes furniture for the home, office, garden and patio. Indoor pieces include sofas, chairs, desks and dressers, while outdoor pieces include wicker chairs and ottomans.Continue Reading
In addition to pieces like chairs and desks, Martha Stewart Living offers kitchen cabinets and counters in partnership with The Home Depot. Martha Stewart Living also produces bathroom vanities and lighting fixtures exclusively for The Home Depot. Martha Stewart's collections at Staples focus on the office and include filing cabinets and lamps.
Martha Stewart Living Omnimedia, Inc., was incorporated in 1996. It produces print, digital and televised media in addition to Martha Stewart Living branded furniture, crafts and decorations. The company's best-known publication is the monthly magazine Martha Stewart Living, but it also publishes Martha Stewart Weddings. Both magazines are available in print and digital formats. Martha Stewart Living also has an Internet presence at MarthaStewart.com, which features craft projects, recipes and videos.
Martha Stewart Living partners with several retail stores that sell Martha Stewart branded products. For example, its collections at Macy's range from bedding and bath textiles to dinnerware and decorations. Martha Stewart Living also sells a line of pet accessories, such as pet beds, clothing, collars and grooming tools.Learn more about Furniture
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https://www.reference.com/home-garden/kind-furniture-martha-stewart-living-produce-4c8765a05b18db3a
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To be or not to be, that is the question. – Hamlet
After Clain and Phryne were abducted, the terrorist airship started having a problem in the air because Nessa (a dopple of Phryne’s little sister) was hiding somewhere in the ship, and that caused the system to malfunction. The reason why she disappeared was because she was mad at Clain for caring about Phryne more than her. Her melancholy created a problem in a way like Haruhi did. And then, the airship was lost in the thunderstorm. It was urgent to find Nessa to save the ship from crashing.
And after a while, Nessa finally appeared and became cheerful again.
And eventually Nessa went to look for Phryne, and found her. And the airship was stabilized.
At first Phryne didn’t join the dinner table. And she was thinking of escape, but she was found by Nessa (a doppel), and decided to stay in the airship, and started socializing. So, in that sense, Phryne was also “hiding.”
Somehow, this episode reminds me of the Iwato-gakure legend from Japan. Amaterasu, the supreme Sun Goddess, hid behind the rock because her little brother played prank at her workshop. Then, the world went dark, and the gods panicked. So, Uzume volunteered to strip-dance, causing laughter among the gods. Then, curious Amaterasu peeked out and came out again, and the light went back to the world.
So, basically the theme of this episode was Hide-and-seek. Nessa was it, playing fort/da, Inai-inai-bā (it isn’t here, isn’t here, here it is!). And the word “it” is “oni (goblin)” in Japanese. “Il y a” in French. And oni must touch a chasee in order to quit being oni. Yes, touching, skinship indeed.
Peekaboo is usually played with infants. But peekaboo is also played by grownup girls, especially nubile girls! It’s been recorded that if a girl sees her potential mate at a restaurant, she hides her face behind a menu book, and peeks at him, and giggles. Girls during the Victorian period used a hand-held fan to do that. Yes, fort/da is a foreplay to skinship. Just like St. Peter got the Keys of Heaven, peekaboo is a Key To Skinship.
Geekaboo vs Meekaboo
How awesome is peekaboo… So I’ve been hiding behind my DS, yet has anybody sought me? Bother to even dance and flirt? So, I’m always fort, left in the dark. So, I play fort/da by myself since there’s no da, no light in 3-D. Who’d say “Da!” like Antonio Inoki? So, I want Nessa to exclaim, “1, 2, 3, da! Il y a LaMoe!” Or should I go to a maid-café and request “1, 2, 3, da!“?
The eyes of contempt, I want to hide away from. We’ve had enough of Search and Destroy instead of Hide-and-seek. Cops and soldiers wear a helmet and shades to remain faceless, like that Goya’s painting. Just like dullahan, Celty from Durarara! But the eyes of appraisal, I want to get exposed to. That will surely make me narcissist, instead of being a self-loathing meek.
Recent success of the geek, evident in the movie The Social Network, now they’re getting loads of peekaboo from 3-D chicks. The geek have betrayed us. Et tu, Brute? While we otaku/hikikomori/NEET never get that. Screw geekaboo. What we need is meekaboo. Blessed are the meek! For we will find 2-D girls! Thus,
2-D or not 2-D, that is the question.
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http://animediet.net/reviews/anime-reviews/fractale-episode-5-2-d-or-not-2-d
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http://iowagravestones.org/gs_view.php?id=166214
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[on tan stationery with a red drawing of “Pacifica”]
Mar 28th 52
My Dear Laura,
How are you I received a letter one from Jane and one from Betty. Betty said she had the measles I hope they don’t all get it. Are you coming for Conference. Jane said you had some Hand Lotion you were going to bring to me;. I would like some if you have any to spare.
I hope you are well. We will be expecting Harold anyway. I haven’t seen Mother Carlson for some time I think she has been busy over at Gordon’s, as Ruby is still in bed, and Mother Carlson hasn’t been feeling up to Par herself. It might have been the bad weather that we were having for so long. There was a lot of sickness around. The sun has been shining the last two days so it makes us all feel better. People will be thinking of Gardening and House cleaning now. We are all pretty well here. The last snow is nearly all gone. There is still some on the north side of the house but the roads are all drying up.
Conference is only one week away. We have fast Sunday on the 30th Mar. That is Roland’s birthday and I have not written to Him. I had a letter from Kathryn but she didn't have much news of the family. They have had bad weather up there too. They are all well she said. I guess Roland is busy with church work and insurance and Red Cross, so it keeps him busy. I haven’t heard from Lois for a long time. She usually gives me all the news. Kathryn didn't say if any one from up there was coming for Conference.
I hope all your neighbors and friends are well. Remember me to all of the Relief Society Ladies. Tell Sister Rumsey and Richardson that I appreciate their letters and will write to them some time. I think of them all often and Pray for them. How is Opal and family. Don’t forget my Pills I had to get new glasses and they cost me a lot and I have to wear them all the time. I took money out of the bank to pay for them, and paid $17. for a coat for Spring. It isn’t very good but it will do, it is a nice gray color. I am hurrying this for the mail man. Take care of yourself and hug all the children for me. Hope Alice doesn’t get the measles.
Bye Bye May the Lord Bless you always. Lovingly Mother.
Tell Betty & Jane I will write to them some time. Love to Harold and will be glad to see him.
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http://mailfromthepast.blogspot.com/2014/03/measles.html
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Find here some delicious low fat low carb recipes you can use after your cabbage soup diet week.
The problem with many low fat, low carb diets is that not only can they be difficult to try and plan, but they’re also usually pretty boring and tasteless too. However, we’ve come up with some ideas here, no matter what time of day the meal’s for:
This recipe is for a fast and refreshing breakfast, and can easily be added to with different flavours like salsa:
1 cup baby spinach, chopped
1/4 cup egg whites
1/4 cup reduced-fat cheese, shredded
1. Use butter spray to lubricate a microwaveable dish.
2. Put spinach in dish, with the cheese on top.
3. Add the egg whites.
4. Microwave for 2 minutes – you should see the egg whites get puffy.
5. Take out, stir, then microwave another minute until dry on top.
One of the most common ways that people put on weight is by getting lazy in front of the TV. If this is you, then this is an ideal snack for you.
All you need is a dozen corn tortilla chips, salt and vegetable oil. Brush the tortillas with the oil and cut into 6 wedges. Arrange them into a single layer and microwave them for 90 seconds. Turn them, and then repeat. Continue this turning and 90 second cooking until all the wedges are crisp. Take out the microwave and add salt.
A great and easy accompaniment for the chips is low fat mango salsa, which is also low in carbs. All you need is 2 mangos, peeled and cubed; 3 tablespoons of basil, finely chopped, half a cup of diced red pepper, 4 teaspoons of lemon juice, 3 tablespoons vinegar, salt and 2 jalapeno peppers, chopped and with the seeds removed. Mix them all together in a bowl, then leave at room temperature before serving.
Something I really enjoy is an Ostrim meat stick. Not only are they delicious and healthy for you, they’re low in carbs, calories and fat! The Teriyaki is a particular favourite.
Another favourite of mine is wild rice. It’s great with salads, and ideal to freeze for when you want to use it, and again it’s low in carbs.
Curried Cauliflower Soup - Low Carb, Low Fat
1 tablespoon olive oil
1 chopped onion, medium size
1 minced garlic clove
1 head cauliflower, broken into florets
5 cups stock (chicken or vegetable)
1 cup water
1/3 cup rolled oats
1/2 teaspoon salt
1/2 teaspoon pepper (white is best)
1 teaspoon curry powder
1. In a large pot, sauté the onion and garlic for around 5 over a medium heat
2. Add the cauliflower, and sauté for another 5 minutes.
3. Mix in the other ingredients, bring to the boil and then simmer for 15 minutes
4. Use a blender to puree into separate batches, then pour back into pot and adjust with spices to taste.
Since our cabbage soup recipes are all low fat and low carb, once your diet finishes why not continue taking the soup? It’s tasty, easy and healthy all in one!
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http://www.successful-diet-cabbage-soup.com/low-fat-low-carb-recipes.html
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Hyperallergic welcomes your comments on posts. Our goal with comments on Hyperallergic is to build a smart, entertaining and engaged community.
We don’t want our commenting culture to suck, so all comments will be moderated after they are posted and may be removed if you:
- abuse other commenters or authors
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We’ll take every comment seriously — or with humor, when required — but we also take attacks and abuse of others seriously as well, so we have no problem banning people from commenting on Hyperallergic if they’ve proven themselves irresponsible.
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Please don’t just comment to promote something you’re working on. You’re more than welcome to buy ads on this site or send us an email to pitch a story.
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https://hyperallergic.com/comment-policy/
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|ITV transmission date||27th February 1963 (Wednesday)|
|Stories by||Harry Driver|
|Previous episode||25th February 1963|
|Next episode||4th March 1963|
Elsie warns Joe to do right by Christine. Jerry tells Len that he's been offered another job. Christine tells Elsie she's going to finish with Joe. Len advises Jerry to take the offer if he doesn't want a partnership in a few years. Jerry decides to stay with Len. Christine is relieved when Joe finishes with her. She tells Frank she will marry him.
- Christine Appleby - Christine Hargreaves
- Elsie Tanner - Patricia Phoenix
- Annie Walker - Doris Speed
- Harry Hewitt - Ivan Beavis
- Concepta Hewitt - Doreen Keogh
- Lucille Hewitt - Jennifer Moss
- Jed Stone - Kenneth Cope
- Jerry Booth - Graham Haberfield
- Len Fairclough - Peter Adamson
- Alf Roberts - Bryan Mosley
- Doreen Lostock - Angela Crow
- Miss Nugent - Eileen Derbyshire
- Leonard Swindley - Arthur Lowe
- Minnie Caldwell - Margot Bryant
- Martha Longhurst - Lynne Carol
- Frank Barlow - Frank Pemberton
- Valerie Barlow - Anne Reid
- Florrie Lindley - Betty Alberge
- Kenneth Barlow - William Roache
- Last appearance of Alf Roberts until 26th August 1963.
- TV Times synopsis: Jerry faces an awkward decision; and Lucille digs into the past.
- Viewing Figures: First UK broadcast - 8,553,000 homes (1st place).
|February 1963 episodes|
|Mon 4th • Wed 6th • Mon 11th • Wed 13th • Mon 18th • Wed 20th • Mon 25th • Wed 27th|
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http://coronationstreet.wikia.com/wiki/Episode_231_(27th_February_1963)
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Kinematics: Displacement, Velocity & Speed
Transcript of Kinematics: Displacement, Velocity & Speed
the time interval of 3 minutes. A football coach paces back and forth along the sidelines. The diagram below shows several of coach's positions at various times. At each marked position, the coach makes a "U-turn" and moves in the opposite direction. In other words, the coach moves from position A to B to C to D. What is the coach's average speed and average velocity? Displacement vs. Distance Frame of Reference Average Velocity Average Speed Instantaneous Velocity Distance vs. Displacement Distance: a scalar quantity which refers to "how much ground an object has covered" during its motion Displacement: a vector quantity which refers to "how far out of place an object is"; it is the object's overall change in position. Scalar vs. Vector Scalar: quantities which are fully described by a magnitude (or numerical value) alone
Vector: quantities which are fully described by both a magnitude and a direction Examples:
a. 5 m
b. 30 m/sec, East
c. 5 mi., North
d. 20 degrees Celsius
e. 256 bytes
f. 4000 Calories Average Speed vs. Average Velocity Average Speed: distance/time interval; "how fast an object is moving"
Average Velocity: displacement/time interval: "how fast an object changes
its position" Runner A is initially 6.0 km west of a flagpole and
is running with a constant velocity of 9.0 km/h due east.
Runner B is initially 5.0 km east of the flagpole and is
running with a constant velocity of 8.0 km/h due west.
What will be the distance of the two runners from the
flagpole when their paths cross? Kinematics Kinematics is the branch of classical mechanics that describes the motion of bodies (objects) and systems (groups of objects) without consideration of the forces that cause the motion. Motion Motion takes place over time and depends on the frame of reference. A frame of reference is a system for specifying the precise location of objects in space. In physics, any frame of reference can be chosen as long as it is used ¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬consistently
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https://prezi.com/0js5jnn_quzk/kinematics-displacement-velocity-speed/
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Description - The Roman Poets by
A collection of urban and pastoral poetry of the Roman republic, and of the empire that succeeded it.
Buy The Roman Poets by from Australia's Online Independent Bookstore, Boomerang Books.
(166mm x 115mm x 18mm)
Everyman's Library USA
Publisher: Random House USA Inc
Country of Publication:
Book Reviews - The Roman Poets by
Author Biography -
Peter Washington is the editor of many of the Everyman's Library Pocket Poets, including Love Poems, and is the author of Madame Blavatsky's Baboon: A History of the Mystics, Mediums, and Misfits Who Brought Spiritualism to America.
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https://www.boomerangbooks.com.au/book.cfm?isbn=9780375400711
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DANIEL 5:10-12; Now the queen, by reason of the words of the king and his lords, came into the banquet house: and the queen spake and said, O king, live for ever: let not thy thoughts trouble thee, nor let thy countenance be changed: There is a man in thy kingdom, in whom is the spirit of the holy gods; and in the days of thy father light and understanding and wisdom, like the wisdom of the gods, was found in him; whom the king Nebuchadnezzar thy father, the king, I say, thy father, made master of the magicians, astrologers, Chaldeans, and soothsayers; Forasmuch as an excellent spirit, and knowledge, and understanding, interpreting of dreams, and shewing of hard sentences, and dissolving of doubts, were found in the same Daniel, whom the king named Belteshazzar: now let Daniel be called, and he will shew the interpretation.
Divine recognition are orchestrated to bring you to a place of greater honour. You will realize that most times where there is a recognition there is a cause for elevation but it pains me to see that there are people who the devil has blind folded the eyes of their helpers the eyes of people who are suppose to recognize them to think negative about them. When there are lots more positive things to think about them but today God will cause such happenings to change. There shall be a divine transaction and conversation shall happen in your favour and great people shall recognise you for good. Helpers shall remember you for good and you shall be brought into a place of honour. The grace for generational favour shall locate you today. Manipulation in the minds of your divine helpers and destiny connectors ends today. Your long wait is over and crying days are over receive call of elevation. A divine set up for manifestation of greatness happens now, Amen!
TODAY'S TIP: IT IS GOD THAT JUSTIFIES !
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http://efecollabs.blogspot.com/2017/05/daily-prayer-nugget-may102017.html
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About Quicken Loans
Quicken Loans is the largest online mortgage lender and has got over 25 years of experience in offering tailored loan programs and mortgage options through its interactive website and loan centers in Michigan, Ohio and Arizona. Its online operation has great recognition among people. When you are racking your brains to choose a mortgage loan or helpless in affording your current monthly payment, Quicken Loans will definitely put forward excellent mortgage refinancing plans to deal with all your problems, including fixed or adjustable-rate mortgages, reverse mortgages, and refinancing loans.
The reason why Quicken Loans has earned great popularity is that powerful loan calculators make the entire application process easy and quick. As long as you answer several questions from the advisor, you will be given advice about which plan is proper for you.
Interest rate is one of the most important things you should take into account while you choose home mortgage. Quicken Loans boasts the most competitive rates which will be helpful to people who wish to refinance their home mortgages.
30-Year Fixed Rate Mortgage
Quicken Loans provides a 30-Year Mortgage with fixed rate which is as low as 3.875% and 1.375 points due at closing. Loan amounts range from $25,000 to $2,000,000. You’re required to pay the down payment which can be only 5 % of the total value if you get your first house. The monthly payment, which doesn’t include taxes and insurance premiums, will be $1,058 and the actual APR will be 4.049% if you get loan with an amount of up to $200,000. Your payment will never go up because of the unchanging rate. It’s for you if you are upset with the increasing payments in the future.
15-Year Fixed Rate Mortgage
This loan program has a 3.125% fixed rate and 1 point due at closing. You monthly payment will be no more that $1,505 for a $200,000 loan and of courses exclude any tax and insurance premium. The actually APR which is only 3.504% makes 15-Year Fixed Rate Mortgage a good way to reduce the total amount of money paid for your home. Lower rates and a shorter term mean that you will pay less interest totally. For a $200,000 loan amount with 2 points, a 15-Year Fixed Rate Mortgage will help you save $87,791 all over the life of the loan, compared with the fixed rate mortgage with 30 year term.
7-Year ARM Mortgage
7-Year ARM mortgage is an adjustable rate mortgage. Whether it will be beneficial to you or not depends on your current financial situations and estimate of your future life. If you apply for a loan with an amount of $200,000, considering the current rate of 3.75% and 1.75 points due at closing, monthly payments, including the principal and interest will be $859. What you should keep in mind is that the rate is adjustable with the market conditions. Therefore, it may benefit you or cost you much more in the long run.
5-Year ARM Mortgage
For 5-Year ARM Mortgage, the rate is 3.25% with 2 points due at closing. For the loan with an amount of $200,000, the principal and interest payment is $847.
Quicken Loans Official Website: http://www.quickenloans.com
Ranking the fifth largest retail mortgage lender in the U.S., Quicken Loans is a Detroit based lending company that has been offering mortgage solutions for more than a quarter century.
This web site is not affiliated with Quicken Loans. We recommend Quicken Loans official site for more accurate information of its financial services.
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https://www.loans-advisor.com/loan-business/quicken-loans/
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Friday, August 22, 2014
How Many Times Have You Spotted A Lamp Like This At An Estate Sale Only To Find A NFS Tag On It?! At Least 'Round Here They LOVE To Keep These All To Themselves. Status: Availbable.
Makes sense. These are great for lighting a display of goodies at an estate sale. They also do the trick if you're just needing a little illumination to read by in your favorite nook.
Each lamp head has it's own switch so that the user has complete control over the lighting. Some of
these lamps have one Three way switch which give you a couple combinations of heads but
ultimately leaves one wanting. Also kind of a rare find, this tall three way floor lamp is in white. I
almost always find these in black or sadly, avocado. I know I should probably have embraced
avocado ( the color, not the fruit - I LOVE the fruit!) but I just can't. If it were more like the
contemporary avocados out there today I would love it, but that drab avocado of the late '60s? No
Oh, and look how at home this loverly retro floor lamp looks next to the Russel Wright folding chair!
Nice, right? I was surprised to find the cones in good condition with only minor scratches here and
there. There is some rust on the base but c'mon, who looks at the base? Everybody will be too busy
swooning over the upper half of this beauty to notice so I thought it might be a good idea to mention
it. I've already tagged this and dropped it off at the Antique Mall of Creve Coeur so hopefully it'll
find a new home soon.
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http://mistermodtomic.blogspot.com/2014/08/how-many-times-have-you-spotted-lamp.html
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Wallabies winger Wendell Sailor has received an additional two-match ban from the Australian Rugby Union for his recent drunken behaviour in Cape Town.
Sailor switched from Queensland to New South Wales this season
Sailor was already suspended for one match, fined A$500 by his New South Wales team and sent home.
But he had a suspended ARU two-match ban hanging over him from another indiscretion with the Wallabies last year in the same South African city.
The ARU also fined him an extra A$3500 for the latest incident outside a club.
He was unavailable for the Waratahs' Super 14 game against the Stormers with a hamstring strain, and was out drinking in Cape Town the night before the game.
Sailor reportedly pushed a fellow nightclub patron to the ground outside the club after he had gone outside to make a phone call.
"The guy was in my space and I was outside trying to make a call and he was following me, but still, I'm a bit better than that, and it's obviously not something I need to be doing in the position I'm in," he said.
Sailor said he had also vomited outside the club, but could not really remember the scuffle. "Probably had a few too many drinks at the bar in that space of time," he said.
NSWRU chief Fraser Neill said at the time: "It's disappointing and we find it totally unacceptable behaviour."
Sailor, later describing it as "probably the lowest point of my career", added: "I'm pretty disappointed with myself."
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http://news.bbc.co.uk/sport2/hi/rugby_union/4731112.stm
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AGENDA FOR TALKS WITH INDONESIA AND AUSTRALIA APPROVED
East Timor's Council of Ministers approved today the agendas for bilateral and trilateral talks scheduled to take place next week in Denpasar, Indonesia.
The agenda for the 25 February bilateral meeting between East Timor and Indonesia includes topics such as: the ownership of property that belonged to the Government of Indonesia and Indonesian citizens on August 1999; pensions for former Indonesian public servants and retirees; refugees; border demarcation; and cooperation in the cultural, education, banking and monetary sectors.
In addition, a discussions are expected on the establishment of postal links; regular trans-border movement and trade; and a protocol of cooperation between the police services of both countries.
The agenda for the 26 February trilateral meeting between East Timor, Australia and Indonesia includes issues of common interest for the three countries, in particular: security, cross-border crime and management of borders; repatriation of refugees; and economic and developmental cooperation and assistance.
The Council also decided that petroleum exploitation in the Timor Sea should not be part of the trilateral agenda.
The East Timor delegation will be led by Special Representative of the Secretary-General Sergio Vieira de Mello, and includes Chief Minister Marí Alkatiri, Foreign Minister José Ramos-Horta, Secretary of State for the Council of Ministers Gregório de Sousa and the Government Advisor on Human Rights Isabel Ferreira .
Ramos-Horta has described the tripartite meeting - the first of its kind - as "a milestone both in the history of East Timor and in regional relations."
In addition, Ramos-Horta and the committee responsible for the Independence Day Celebrations briefed the Council on the activities related to 20 May. The festivities will include an East Timor Expo, to be constructed at the site of the old Dili Central Market with a US$1.2 million donation from the Australian government.
The Council was also briefed on proposals to build two national monuments: an independence monument funded by the Australian government; and a monument to pay homage to Nicolau Lobato, the first commander of the resistance movement Falintil, killed in December 1978, funded by the Portuguese government.
The Council of Ministers also studied a draft regulation on the establishment of a Public Broadcasting Corporation for television and radio. The Council decided to create an inter-ministerial commission that will review the constitutionality of the draft and its financial implications.
Finally, the Council approved the Finance Minister's proposals regarding the budget for the fiscal year of 2002-2003, which will be presented at a 14-15 May donors conference in Dili.
HEALTH MINISTER, SRSG DEDICATE CENTRAL MEDICAL STORE
Health Minister Dr. Rui Maria de Araújo and UN transitional administrator Sergio Vieira de Mello led the official opening today of East Timor's Central Medical Store, a medicines warehouse that is the distribution hub of the national health system.
A ribbon cutting and live traditional music highlighted the dedication ceremony for the US$1.3 million building. De Araújo described the moment as a "turning point" in the management of a public health system that has struggled to rise from the ashes of violence that surrounded the end of Indonesian rule in 1999.
"The challenges are huge … but here we have the system to ensure that we are properly procuring, storing and distributing medicines in East Timor," the minister said.
Vieira de Mello called health and education the top priorities of UNTAET and East Timor's Second Transitional Government. Displaying a photograph of a burned-out shell of a building that was the territory's central pharmacy before the 1999 violence, the Special Representative of the UN Secretary-General (SRSG) illustrated the "nightmare" of medicine procurement and distribution that existed in East Timor just a few months ago.
The SRSG also applauded the Health Ministry, foreign donors and the World Bank for making the Central Medical Store a reality.
Construction of the Central Medical Store was managed by the World Bank. Donors included Australia, the European Union, Finland, Ireland, Italy, Japan, Portugal, Norway, the United Kingdom, the United States, the Asian Development Bank and the World Bank.
The US military's Support Group East Timor (USGET) donated US$350,000 in office and medical supplies to the Central Medical Store last month. AusAid contributed an additional A$250,000 (US$129,500) in medical supplies.
GUSMAO, BISHOP BELO CALL FOR MORE CONSTITUTIONAL DEBATE
Independence leader Xanana Gusmão and Dili Bishop Filipe Ximenes Belo urged the Constituent Assembly today not to rush passage of East Timor's first Constitution, saying more time was needed for an upcoming public consultation on the historic document.
Speaking at the start of a televised public discussion organised by the east Timor Study Group, Bishop Belo called for the entire month of March to be devoted to the nationwide public review of the Constitution. He said the current consultation schedule - from 26 February to 2 March - was akin to "teasing" the public.
"This is our Constitution, our life, our future and our faith - therefore we shouldn't be in a hurry,'' the Bishop said.
Gusmão said he had recently expressed similar sentiments to UN Secretary-General Kofi Annan. He added that he did not think the Constitution must be completed by East Timor's independence on 20 May.
"There are countries that became independent without having a Constitution," Gusmão said. "A Constitution is the pillar of a nation. It is the mother of law, and it should be properly legitimised by the people."
The popularly elected Constituent Assembly has spent more than four months drafting the Portuguese-language Constitution. After the public consultation, there will be final period of debate before its promulgation at a 16 March signing ceremony.
Today's public discussion was organised by the East Timor Study Group in conjunction with UNTAET's Office of Communication and Public Information. It was broadcast by both Radio UNTAET and Televizaun Timor Lorosa'e.
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http://www.un.org/en/peacekeeping/missions/past/etimor/DB/db200202.htm
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In 1992, the United Nations Conference on Environment and Development (UNCED) was held to talk about environmental issues around the world. Severn Suzuki, a twelve year old Canadian at the time (Now a well known 32 year old humanitarian and environmental activist) spoke at this conference, in front of the entire UN. The video below is her speech.
This year, the UN came back to Rio to have an Earth Summit+20 conference on Sustainable Development on 20-22 June 2012. This year, one of my fellow New Zealanders, 17 year old Brittany Trilford, has had the privilege to speak at the conference by winning the “Date With History” competition.
I would like you to consider, please, how much is different in these two speeches. As Brittany has said, nothing has changed; in fact, the situation grows worse. A NZ Herald article shows that the decisions being made right now, as we speak, at Rio de Janerio, are nothing more than more empty promises, that contain “… absolutely nothing there for people and the planet,” (Daniel Mittler, political director of Greenpeace International). Let us hope that this will change, and solid progress will be heard about in the next two days. I believe that if enough awareness is raised, and influential figures swayed, maybe this year governments will finally do something about the looming problems of Earth. So please, if you are reading this, post a blog, or a tweet, or update your profile and say something about what you think the future should hold for us. It’s not that hard, and it will make all the difference in the world. Because if you are reading this, or know what is happening in Brazil right now, then you are in the position to exert control over the future, by raising your voice and having your say about your future. Please, I ask again, do so.
Let’s call me Lily
To find out more about the conference, click here.
To enter the Goi Peace Foundation essay competition about creating “The Future We Want”, click here.
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https://saneasiam.wordpress.com/2012/06/21/2012-un-earth-summit-conference-in-rio-de-janerio/
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3. My hot new boyfriend Bobby went from chess dud to vamp stud.
4. No reflection! First order of business: turn my own stylist to stop the downward spiral from chic to eek.
5. Vampire vixen Mellisande has taken an interest in my boyfriend, and is now transforming the entire high school into her own personal vampire army. If anyone's going to start their own undead entourage it should be me.
I guess I'll just have to save everyone from fashion disasters and other fates worse than death."
Found this at the used bookstore. Sounds like it could be funny.
Dead Is So Last Year by Marlene Perez
Pub. date: May 09
"Something very strange starts happening in Nightshade the summer that the eldest Giordano sister, Rose, gets a job working at Dr. Franken's research laboratory. People are starting to see double. Doppelgängers of Nightshade residents are popping up all over town. Daisy, Rose and Poppy think it's a coincidence, until the rumors start that their father, who disappeared several years ago, has been spotted in town. Meanwhile, Daisy's beau, Ryan is spending all of his time training for football, and like the other guys on the team, he's grown enormous almost overnight. Samantha Devereux's boyfriend's neck has doubled in size since school ended. Could the football players be resorting to extreme measures to win? Between summer jobs, sugar rushes, and beach parties, the Giordano girls get to the bottom of these mysteries and more."
Confessions of a Closet Catholic by Sarah Darer Littman
Pub. date: February 05
"Justine Silver's best friend, Mary Catherine McAllister, has given up chocolate for Lent, but Justine doesn't think God wants her to make that kind of sacrifice. So she's decided to give up being Jewish instead.
Eleven-year-old Justine pours her heart out to her teddy bear, "Father Ted," in a homemade closet confessional. But when Justine's beloved Bubbe suffers a stroke, Justine worries that her religious exploration is responsible. Worse, she must suddenly contemplate life without Bubbe. Ultimately, it's Bubbe's quiet understanding of Justine's search for identity that helps Justine to find faith in the most important place of all-within herself."
Spent an hour and half in the car, then another hour in a Catholic bookstore, and this was all I found. Sounds like it might be good. I like the cover. :)
Faerie Wars by Herbie Brennan
Pub date: September 04
"When Henry Atherton helps Mr. Fogarty clean up around his house, he expects to find a mess and a cranky old man; what he doesn't expect to find is Pyrgus Malvae, crown prince of the Faerie realm, who has escaped the treacherous Faeries of the Night by traveling to the human world through a portal powered by trapped lightning. An egomaniacal demon prince, greedy glue factory owners Brimstone and Chalkhill, and the nefarious Lord Hairstreak, leader of the Faeries of the Night, all dream of ruling the Faerie realm and are out to kill Pyrgus. Enlisting the help of his sister, Holly Blue, and his new friend, Henry, Pyrgus must get back to the Faerie world alive before one of his many enemies gets to him instead. But how many portals are open, and can Pyrgus find the right one before it falls into the wrong hands? Conjuring scenes filled with vivid color, unforgettable detail, and fearless characters, author Herbie Brennan brings readers to the Faerie world, where nothing is ever what it seems and no one can be trusted."
I've been craving faerie books lately. I don't know why, I've never been particularly interested in them before, but recently I found myself needing a faerie book. So, I went online and searched my library system for faerie books (after searching them and asking about them on Shelfari), and this is one of the ones I found.
Tantalize by Cynthia Leitich Smith
Pub. date: February 07
"CLASSIFIED ADS: RESTAURANTS SANGUINI'S: A VERY RARE RESTAURANT IS HIRING A CHEF DE CUISINE. DINNERS ONLY. APPLY IN PERSON BETWEEN 2:00 AND 4:00 PM.
Quincie Morris has never felt more alone. Her parents are dead, and her hybrid-werewolf first love is threatening to embark on a rite of passage that will separate them forever. Then, as she and her uncle are about to unveil their hot vampire-themed restaurant, a brutal murder leaves them scrambling for a chef. Can Quincie transform their new hire into a culinary Dark Lord before opening night? Can he wow the crowd in his fake fangs, cheap cape, and red contact lenses — or is there more to this earnest face than meets the eye? As human and preternatural forces clash, a deadly love triangle forms, and the line between predator and prey begins to blur. Who’s playing whom? And how long can Quincie play along before she loses everything? TANTALIZE marks Cynthia Leitich Smith’s delicious debut as a preeminent author of dark fantasy."
Saw this at the library and read the first few pages. Wasn't bad, so I decided to get it.
That's all I got this week. Not a bad week, I'm gonna be busy for while. ^_^
SS is hosted by Rating Reads. To participate simply...
Take your current read or recently finished book.
Find at least one song that fits the story, characters, whatever.
Post the book title and song(s) on your blog with a brief explanation of your picks. Don't forget to mention who started it.
Songs:Hungry Like the Wolf by Duran Duran and We've Got a Big Mess on Our Hands by The Academy Is...
Why Hungry Like the Wolf? The werewolves of Nightshade played a bigger role in this one, and with werewolves comes an appetite for raw meat, hence the song.
Why We've Got a Big Mess on Our Hands? The video for this actually fits the book pretty well. The citizens of Nightshade have a little problem with sugar crazed doppelgangers popping up, ruining the lives of the originals. Since the doppelgangers are evil, and one in particular causes the Giordano sisters some trouble, the lyrics fit too.
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http://all-by-myshelf.blogspot.com/2010/01/in-my-mailbox-22-soundtrack-saturday-2.html
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*Age Of Consent & Legal Sexual Activity for the State of
22nd June 2007 Letter from the office of Hon. Attorney-General Mr. Kerry Shine in reply to my 18th May 2007 letter and DVD-Video/CD-ROM pack. The Attorney-General merely repeats the Beattie Government’s standard line of “no … plans for reform in this area” – with absolutely no justification for that inaction. This is in spite of the fact that the six statements on the DVD made it very clear that the current law should be reformed urgently because the law has a severe negative impact on the health and well being of youth – and also because the Anti-Discrimination Commissioner has declared that the law is blatantly discriminatory.
Office of the Attorney-General and Minister for Justice
and Minister Assisting the Premier in
In reply please quote: 2007103693 J/07/03232
22 June 2007
Mr John Frame
82 Main Avenue
WAVELL HEIGHTS QLD 4012
Dear Mr. Frame
Thank you for your letter dated 18 May 2007 with the
attached DVD entitled “6 Statements of Support for Equal Age of Consent Reform
Honourable Kerry Shine MP, Attorney-General and Minister for Justice and Minister Assisting the Premier in
on his behalf.
All the issues raised in the statements recorded on the DVD
have been noted, however, this Government holds no immediate plans for reform
in this area.
Thank you for raising this matter with the Attorney-General.
Senior Policy Advisor
Level 18 State Law Building
50 Ann Street Brisbane
GPO Box I49 Brisbane
Telephone 4-61 7 3239 3478
Facsimile +6173220 2475
ABN 6 959 415 158
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http://queerradio.org/AOC220607.htm
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INTAGE WEDDING INVITATIONS What a great way to set the tone of your wedding! A perfect blend of Art Nouveau merging into Art Deco! These invitations can accommodate your custom wording and wedding colors and can be used as Save the Dates or in a full invitation suite with reply cards, info cards, menu's, placards etc. Designed by GoGoSnap!
Gold Deco Wedding Invitation Set, Printable, Custom Invitation and Reply Card, Art Deco, Vintage Wedding, Gold, Grey | Deco & I Do
Gold Art Deco Fan Wedding Invitation Reply Card This black and gold art deco reply card keeps the suite's dark, romantic look with white boxes for guests to write their information in. Faux gold glitter scallops sweep across the top of the card and feature a matching backer of the same pattern to tie the whole suite together.
Art deco wedding invitations are a gorgeous addition to any art deco inspired event. Printed with gold foil, these gold wedding invitations have a die cut pocket to hold the ticket style response card. Click to see all of the details or PIN to save for later!
Gatsby Garden Wedding Invitation - Art Nouveau, Art Deco - Invitation Sets, Art Nouveau Wedding - Vintage Invitation - Sample or Deposit
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https://za.pinterest.com/explore/deco-reply-cards/
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a:1:i:0;a:2:s:13:”section_title”;s:30:”Pet Shop Hop Tips & Tricks”;s:12:”section_body”;s:22925:”
Check out our Tips & Tricks for Pet Shop Hop.
This game has 52 levels and is divided by weeks of the month. Some months are 4 weeks long and others are 5 weeks long. This game saves differently than most. The majority of games will save the progress you’ve made up until the last day that you played. Pet Shop Hop will start you back on the first day of the week for that month.
For example, May has 5 weeks, 9-13. You have to play until the end of the week in May or you will have to start back at week 9 once you restart the game. It is best to play through all the weeks in a particular month if you don’t want to restart a few weeks back. Especially in rounds which you may have found particularly hard to beat.
In the early stages of the game, if the dogs or cats get out of the cage, grab them and take them back to their pen. If you get them right away you will not have to worry about getting the mop and cleaning their mess. After week 22 you will be able to buy the Tidybot which will automatically clean the mess up for you.
Don’t always worry about picking up stray pets once you have the Tidybot. Since the Tidybot cleans up all of the mess your pets leave behind you don’t have to be in such a hurry to pick up all the animals that get out of their cages right away. Sometimes its good to let them wander as long as it doesn’t interfere with what you are doing.
You will see a lady in a fur coat that walks through the store and never buys anything. When she shows up she disturbs your patrons. As soon as you see her come in, make sure you click on your pet and she will go away.
Hamsters do not show up until level 41, however you may see requests for them even before they become available for purchase. When the customers ask for them before that level, find a cage and place different animals in it until the customer accepts one of them. The two most common ones the customers would accept were the yellow birds and the black hedgehogs. Send your pet out when you see these customers in order to try and keep them in the store longer while you figure out a substitution for you to sell them.
If there’s something you want to buy and can’t afford at the time, sell some pets or items from your inventory. You can click on the minus sign in order sign sell some of your pets back into inventory and recoup some of your money. When you buy animals, the number that is in between the (+) and (-) signs indicates how many of that kind of pet you have in stock. Try to keep enough of each type of animal so that you don’t run out, but not too many or you’ll spend too much time cleaning and feeding them.
You can and should replenish your stock at the beginning of each week. There’s a limit to how many of each type of pet you can buy. When buying cats or dogs you can only buy up to 5 of them at a time. Make sure you always the buy maximum of cats and dogs since you make a good profit from selling them and you can only buy a small amount.
Since you are limited as to how many cats and dogs you can buy each week, save them for the people who actually request them.
Pay attention to your audio and visual clues. Throughout the game there will be various tasks that you need to perform in order to keep your shop running smoothly. Make sure that your animals are being fed and that their cages are being kept clean. Perform services, like feeding the animals, cleaning a cage or tank as soon as you see it flashing. You don’t want to wait until the service absolutely has to be performed in order for you to do it. You can also do it before it starts flashing, if you see something getting low just go ahead and do it.
If it’s the end of the day you don’t have to worry about feeding the animals or cleaning stations. Concentrate on taking care of the last customers and making them buy as many extras as possible.
If you’re close to the end and need some points to pass the level, make sure you either sell an accessory, a cage or a bowl. You can also take your most expensive animal and certify it so you can earn more money.
Certain things have to be performed in a certain order or they cannot be done. You cannot fill the bowl with water, place a fish inside and then try to place the gravel in it as well. You have to place the gravel in the bowl, then take it to the water station and lastly place the fish inside.
You can use the recycle bin to place things back into inventory that you do no need, doing so does not cost you extra points. If you picked up an animal by mistake then you can click on the cage or pen that you got it from in order to return it.
There will be times when you’ll fail a level or you may want to replay to up your score. When you restart the game you will be able to make new choices and start fresh.
When you take care of the man in the dark suit and glasses you get a $500 Agent Bonus.
Get whatever is closest to you, if you are making a delivery and somebody wants a fish grab it before you head out.
Some customers will only buy a pet if it has been vet certified, make sure you take them to the vet station when an order for that has been placed. Customers will pay more money for pets that have been vet certified. If you pick up a pet from the vet station by mistake and have nowhere to put it at the moment, drop it back on the vet station until you are ready to take care of it.
When you have 2 animals in your hand and you click on the vet station, the first animal you picked up will be the one to go there.
Customers have different requests, which are represented by the speech bubbles above their head. It’s important to know what they are looking for before you serve them.
If you do not give them what they want you risk the chance of the customer getting impatient and leaving. They can also leave if you don’t have in stock the pet they are looking for.
If a customer has a speech bubble with just a large question mark it means they will accept any animal in any kind of cage that you give them.
An animal outlined in white with a question mark means that the customer will accept that animal in any color.
If the animal is represented in the speech bubble with a particular color and cage, you can only give the customer exactly what they asked for.
When you see a speech bubble with an animal that has a red cross above it, means that you can only serve the customer a pet that has been vet certified.
When you see any animal that is in a cage or bowl, the customer will only buy it if you give them specifically what they asked for. When they ask for pets in cages or bowls you must deliver to them exactly what they ordered or they will refuse it. On the other hand, you can add a cage or a bowl to a customers order in order to make extra money. Let’s say a customer just wants a plain fish in a bag: You can take the fish to the vet station and then put it in a tank with some gravel and water to make more money from that sale
YOUR SPECIAL PET
After level 9 you will be asked to choose between 3 different pets: a Dalmatian, a kitten, or a hedgehog. Whichever animal you choose will be in the doghouse until you click on it to come out and walk around the store and make customers happy. It will also restore a customer’s patience as it walks by.
Your pet will walk down up and down the line with the customers. As your pet walks up it restores most of your patrons’ patience. As it walks back down it will usually finish taking all the red out of a customer’s speech bubble.
It’s important to click on your pet when you see the lady with the fur coat come into the store. She walks around the store and irritates the other customers. If you make your pet come out of the doghouse it will chase her away.
Your pet has to get some rest before it comes out to play again. Pay attention to when the pet is awake and send it out to the customers as often as possible. You will know your pet is sleeping when you see ZZZ’s coming out of the doghouse. You will know its awake when you see eye peering through the opening. At times you may see the ZZZ’s and its eyes open, go by the pet’s eyes being open instead of the ZZZ’s.
At times clicking on things takes a few tries to accomplish. In order to save yourself some time, check and make sure that your actions have been registered properly. Look to make sure that you see a checkmark next to the item you clicked on. If you don’t see a checkmark, do it again. It may be inconvenient to check, especially when you’re on a roll. In the end it’s worth it to take a little extra time to do things right because if you don’t it might make things harder for you.
When you are at the filling stations (gravel and water) make sure that you’ve clicked the correct button. Each button will light up once your cursor lands in the right spot. Once the correct one is lit go ahead and left click your mouse.
If the animals are moving around in their cage, the fish, hamsters, cats, dogs, hedgehogs. Placing your cursor over the desired animal will automatically make it stop moving. As soon as the animal stops moving, click on it to pick it up.
When there are a lot of people standing in line it can be hard to click on the correct person. At moments when the store is full it is best to click on the speech bubble instead of the person. It’s also easier to distinguish which person ordered a particular pet.
If you make any mistakes when picking up an order you can click on the recycle bin to correct your mistake. You can also place an animal back where they belong by clicking on the receptacle that they came out of.
In this game you should never just stand around – you should always be doing something. If you have an order for a bird in a cage that needs to be vet certified, you should do many steps at once in order to save time. Grab the cage and place it in the shaving station, as the cage is filling with shavings grab the bird. Take the bird and place it in the vet station, by the time the pet is ready place it in the filled cage which should be ready by then.
You are able to carry up to 2 things in your hand at once. Try to take advantage of this and have your hands full at all times. Deliver or pick up 2 pets at a time. Grab a pet in one hand and a cage in another etc.
As you wait for a pet to be vet certified, take that time and take care of maintenance around the shop. Feed the animals , clean the cages and wash the floor.
In order to make the most money you need to know which actions will be more profitable for you. The question is, is it better to take a pet to the vet station or serve a customer faster, which one will earn you the most money? You can sell a rabbit for 25 and place it in the vet station and receive $31 for it. Or you can serve it to the customer fast and receive $32, (25 for rabbit and 7 for fast service). In this case you save time and make more money by serving the customer quickly.
You can look out the window and see which customers are waiting to come in. If the line is past your view, then you need to move fast. You should concentrate on getting customers out the door as quickly as possible. This is a good time to obtain chaining bonuses for customers who only have a question mark in their speech bubbles. Sell as many rainbow birds as possible, those birds will earn you more money than any other pet in the store even with accessories, cages or vet certifications. In addition when you sell several birds at one time you get an extra chaining bonus.
In order to make the most money you have to know which pet will make you the most money. Pets become available as you complete certain weeks. Fish make you the least amount of money (except for the rainbow fish) while Rainbow birds make you the most money. You can sell a Rainbow bird for $300 each; always keep in stock the maximum amount of these that you can afford. I would always buy 20 Rainbow birds and sell them as much as possible.
Customers will walk out of your store if you don’t have the pets that they are looking for or if you make them wait too long. A customer’s speech bubble will start turning red when they become angry. It it turns all red, the customer will get angry and leave. You will not lose any points once they leave but you’ve lost a potential sale.
Serve customers as fast as you can and you will earn a speed bonus. As soon as a customer comes in serve them right away. You will mostly be able to earn speed bonuses on orders that only take a single step, like an animal without a cage or certification.
Get another type of bonus by serving the same type of animal as much as possible. It’s important to remember that it is NOT the color of the animal that matters but how many of the same type you deliver.
There are many upgrades you can buy that can help you in a variety of ways. Certain upgrades will make you earn more money and give your customers more patience when they are unhappy. This is a condensed list of the upgrades that will gradually become available to you.
Buy the upgrades right away that allow you to go longer times without having to clean or feed cages. It will save you a lot of time to take care of customers when you don’t have to stop what you’re doing to clean an area.
You don’t have to buy all the upgrades that become available. You can buy them at a later time or don’t buy them at all.
Spring, Summer, Fall and Winter Decor will uplift your customers mood and make them more patient while waiting.
The Vet Station will allow you to certify your pets thus allowing you to earn more money.
Carpet – You can purchase carpet that is stain resistant, which means that you will not have to clean the carpets as often.
Speed Upgrade – State of the art shoes comes along with a book on time-saving tips. Buy this upgrade as soon as it’s available so that you can move around the room much faster. This will enable you to earn a speed bonus as well if you can get to the customers in time.
Tidybot 2000 automatically detects and cleans dirt. This item will automatically clean up a mess as soon as it sees one. You will no longer need your mop once you’ve purchased the Tidybot.
Accessory Stands can hold a variety of items, like different colored collars, bones, fish tank ornaments etc. The accessories are pretty inexpensive to buy. Some customers will request them for their pets so keep a few of each on hand.
Yellow Bird (Level 25) – Good for when you don’t have a color a customer wants you cans sell them the yellow one.
CHRONOLOGICAL ORDER OF EVENTS
Week 12 – Puppies are introduced. Buy the pen so you can keep your puppies for sale in it. Make sure that you buy enough puppies at the beginning of this week or customers will walk out of the shop if you don’t have them.
Week 15 – Kittens are introduced. You can only buy a maximum of five for each week. Buy the maximum amount each time because you will have lots of requests for them.
Week 16 – You can buy the faster shoes. If you read the introduction for that day it recommends that you buy them right away. If you don’t buy the faster shoes you may not be able to pass this level.
Week 17 – Rainbow fish are introduced. Rainbow fish will make you more money than any other colored fish you may have in your tank.
Week 19 – Birds are introduced. They make a good pet for rich folks and older people. You don’t need to feed them often but they make a mess frequently.
Week 20 – Gravel Station is introduced. You will have three gravel colors to choose from. Make sure you press the correct color when filling orders.
Week 21 – Snails are introduced. Placing snails in your fish tank will help keep the tank clean. Buy the snails right away.
Week 22 – The Tidybot is available for sale. It automatically cleans the dirt on the floor. The Tidybot is great because it means that you will not have to take the mop and clean the mess the pets make yourself.
Week 23 – Accessory stands: You will be able to buy collars for your cats and dogs. You will also be able to buy a plastic diver man to place in your tank for added decoration.
Week 24 – Long Bird Perch: Makes smaller cages obsolete. Holds red, blue, and yellow rainbow birds.
Week 27 – Fall Decor is available; buy it to make your customers happier longer.
week 28 – Puppy Feeder: it will make you feed your dogs less often.
Week 29 – Self-Cleaning Litter: You will never have to clean your cat box again.
Week 31 – Superfeeder: You will never have to feed your puppies again.
Week 32 – Bird feeder: You will have to feed your bird less
Week 32 – Superfeeder: For $2500 you will never have to feed your birds again. But you will still have to clean the cage and give them the newspaper.
Week 33 – Hedgehogs are introduced. They make good profits and are easy to manage.
Week 34 – Rainbow Bird is available; you will earn more money with these birds than with any other animal in your shop.
Week 35 – Kitten Feeder: you will have to feed kittens less often.
Week 35 – Superfeeder: You will never have to feed your cats again, the Superfeeder will do it for you.
Week 36 – Hedgehog feeder means that you will have to feed them less often.
Week 37 – Chew Bone: Your dog will chew on it and keep its teeth clean.
Week 37 – Blue Collar: it can go on either your cat or dog.
Week 39 – Flo appears in the store.
Week 40 – Black collar is available.
Week 40 – The hamster wheel is introduced.
Week 40 – Winter Decor will keep customers patient.
Week 41 – Hamsters arrive and are available for purchase.
Week 44 – Hamster feeder: Feed your hamsters less often
Week 44 – Superfeeder: You will never have to feed your hamsters again.
Week 45 – Superfeeder: You will never have to feed your rabbits again.
Week 47 – Flo makes an appearance.
Week 40 – A man in a dark grey suit appears, take care of him and get a Secret Agent bonus of $500
Week 50 – Superfeeder: Your hedgehogs will never go hungry again. It produces pet food and never needs refilling.
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http://www.gamezebo.com/2008/03/20/pet-shop-hop-walkthrough-cheats-strategy-guide/
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We like Parmesan chicken and this version is very easy and delicious. I don’t see why you couldn’t make more of the chicken if you needed to using several pans and increasing the ingredient amounts accordingly.
Parmesan Chicken Bake
1/2 cup butter
1 cup plain breadcrumbs
1/2 cup Parmesan cheese
2 cloves garlic, minced
salt and pepper, to taste
4 boneless, skinless chicken breasts
Preheat oven to 350º.
Melt the butter in a bowl and set aside. Mix the bread crumbs, Parmesan, garlic, and salt and pepper on a plate.
Dip chicken into butter, then into crumbs making sure to cover the chicken with the crumbs.
Put the chicken into a 9×13 baking dish and pour any leftover butter over the top.
Bake for 40 minutes or until the chicken is cooked through and no pink remains.
Makes 4 servings.
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https://nancysrecipes.wordpress.com/2014/04/02/parmesan-chicken-bake/
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Liberal director and conspiracy theory-loving Oliver Stone was actually "fair" to President George W. Bush in his new film "W." Indeed, Stone is practically a "historian" when it comes to chronicling the life of the nation's 43rd president, that is if you ask Newsweek's Alan Brinkley. Of course when measured up against his prior films about American presidents, it's probably not that high a bar to clear.
From his October 11 movie review, "From Man to Mockery, and Back Again":
Through most of the undistinguished history of films about American presidents, concern for truth has been in short supply.
Oliver Stone, whose new film, "W.," is his third examination of a modern president, has aspired to be different.
Oh, it gets better. You see, "W." is "sunny and sympathetic":
Almost all of Stone's important movies are dark and pessimistic, reflections of his own (and much of his generation's) disillusionment with American politics and power. So it is somewhat surprising to see in his portrait of George W. Bush a relatively sunny and sympathetic picture of perhaps the most reviled president in American history.
So why does Brinkley see "W." as a relatively fair and balanced rendering of history? For one, because leftists suffering from Bush Derangement Syndrome will not find a throughly HuffPo/Daily Kos-like portrait of administration principals:
Opponents and supporters of Bush alike will find things to complain about in "W." Bush haters will be startled, and perhaps irritated, by Stone's sympathetic portrait of the young Bush—convincingly portrayed by Josh Brolin—who struggles with (and sometimes bravely stands up to) the intimidating example of his father. (In the film, Bush Sr. continually belittles his son and at one point almost engages him in a fistfight.) Viewers may be annoyed as well by Stone's uncensorious and even admiring chronicle of Bush's struggle to overcome alcoholism and his embrace of Christianity, and by the director's portrayal of Bush's 1994 campaign for governor as a skillful and charismatic effort (albeit carefully orchestrated by Karl Rove). Stone's portrayal of earnest, idealistic conviction among Bush and his advisers about the wisdom of the Iraq War is also inconsistent with the widespread belief that zealotry, deception and ambition were the real drivers of the conflict.
Of course, Brinkley fails to note any convincing evidence that George H.W. Bush was or remains a harsh, pugilistic patriarch, but the accuracy or lack thereof doesn't seem to bother him, perhaps because he chalks it up to being an "educated guess" made within the parameters of Stone's artistic license (emphasis mine):
Stone, like most others trying to chronicle their own time, has undoubtedly made educated guesses about Bush that will turn out to be wrong. But "W." is, nevertheless, different from most earlier movies about presidents (including Stone's own). Whatever its qualities as a dramatic film may be, however its portrayal of Bush may fare in the light of history, it is on the whole an honest effort to find some truth in the blizzard of partisan battles over almost everything associated with this presidency. There are no conspiracy theories, no wild speculations, no paranoia. Stone's film is not hagiography. It is not propaganda. It is, surprisingly, more or less fair.
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https://www.newsbusters.org/blogs/nb/ken-shepherd/2008/10/13/oliver-stone-historian-so-says-newsweek
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The product is a reliable suction pump which is suitable in all application because of its quality performance. Various systems make deployment possible in surgery, intensive care and medicine. The product is designed compact, light and portable, and mainly used in homecare, patient transport, practices of doctors, patient room and care homes. 1.5 liter secretion bottle used for operation and it has suction capacity of 18 l/min. The capacity of suction can be regulated infinitely and accurately. The product operates in low vibration and low noise level. It offers reliability and flexible deployment. The product can be used very easily and it does not require much maintenance. Automatic overflow is prevented. The accessories of the product are available in large choices.
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https://healthmanagement.org/products/view/electric-surgical-suction-pump-handheld-18-l-min-vacuson-18-nouvag
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Companies determine food expiration dates in a variety of ways, depending on the type of food. As of 2015, the only food item required by U.S. federal regulations to be marked with an expiration date is infant formula, so for most other foods, manufacturers are free to set expiration dates at their discretion.Continue Reading
As of 2015, there is no single or universally accepted system for food dating in the United States. However, over 20 states require dating of certain highly perishable foods such as meat, poultry, eggs and dairy products. In the United States, the Food and Drug Administration regulates packaged food and drugs, and the Department of Agriculture oversees the production and packaging of fresh meats and produce. In addition to requiring an expiration date on infant formula, the FDA requires a label identifying packaging date for fresh poultry.
There are typically two methods for dating food ��� either a best-by date or a sell-by date. A best-by date identifies the date by which food should be consumed for the best quality. A sell-by date identifies the date by which food should be purchased. Sell-by dates are typically determined by the amount of time a food item can keep at a given temperature without losing its nutritional value or developing harmful bacteria. Sell-by dates are ultimately determined by the nature of each specific food, according to the food's specific temperature levels over time.Learn more about Food Storage
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https://www.reference.com/food/companies-determine-food-expiration-dates-3f7beb0450420237
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Looking for GED testing in Cora WY? The General Education Development exam is only given in person and not online. Usually to be able to sit for the General Education Development test the test taker must be at least 17 years old. The General Education Development testing fee in the state of Wyoming typically ranges from $40-$90.
The GED examination covers five tests: reading, writing, mathematics, science and social studies. Each test gives a score between 200 and 800. Most states require test takers to obtain a score of 410 on each of the five sections and an average of 450 for the GED test to pass.
Usually GED testing centers in Cora WY are offered at:
- Cora Community Colleges
- Cora ISD
- Cora Literacy Centers
- Cora High Schools
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http://ged101.com/ged-testing-in-cora-wy.html
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In an effort to serve our clients more efficiently, The Weave Bar accepts appointments online. Please be sure to have your credit card ready prior to making an appointment. So that we can accommodate other clients fairly, we require at least 24-hours’ prior notice to cancel an appointment. Appointments may only be canceled online via the confirmation email provided after booking your appointment. Any request to cancel an appointment via email or telephone will not be honored. All appointments are held for a period of 10 minutes after the scheduled appointment time. Should you not arrive within such 10-minute period, your credit card will be charged a nonrefundable fee equal to 50% of any scheduled services.
AFTER REVIEWING OUR APPOINTMENT POLICY
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https://theweavebar.com/appointment/
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Friday, November 30, 2012
PFSweb: Customers See Record Traffic In Holiday Shopping Kickoff
Allen, Texas-based e-commerce services and software provider PFSweb said yesterday that its customers saw record traffic volumes as the holiday shopping season kicked off. The firm said same store order volumes increased by 60% from Thanksgiving through Cyber Monday. The firm said its consumer products goods, luxury, cosmetic, and apparel clients received 364,000 customer orders with an average order value of more than $102.00. PFSweb's report coincides with similar reports coming from a number of sources on a big increase in online orders this year.
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https://www.texastechpulse.com/pfsweb:_customers_see_record_traffic_in_holiday_shopping_kickoff/s-0046505.html
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Sunday, July 24, 2011
NFL Labor Agreement Close! Let's go Lions!
I was very worried that my other favorite professional sport might get cancelled this year. I looks as though the players and the owners are working it out! This is important especially for the Detroit Lions fans. We have some momentum and some talent. This is the year that we take the next step to becoming a winning franchise.
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http://bucketofshrimp.blogspot.com/2011/07/nfl-labor-agreement-close-lets-go-lions.html
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Genre : Melodrama, Romance
Starring : So Ji-Sub, Han Hyo-Joo
Release date : October 20, 2011
Runtime :108 min.
Directed by: Song Il-Gon
Chul-min (So Ji-Sub) leads a hard life delivering the water by day and working at the parking lot by night. His life seems nothing but ordinary, however, he hides his dark past that he used to hit the people for living. One day a strange blind woman called Jung-hwa (Han Hyo-Joo) visits him at the parking lot, who changes his life completely. Looking at cheerful and bright Jung-hwa, Chul-min slowly opens his mind. Jung-hwa also lets him enter her lonely world. To lead a better life with the new love, Chul-min re-starts boxing dreaming of the future as a MMA fighter. But always the good time ends soon. As Chul-min finds out that Jung-hwa might lose her eyesight forever if she doesn’t receive the transplant operation soon and he himself is responsible for the accident which took Jung-hwa’s eyesight and her parents away five years ago, he falls into despair. Burdened with the complex feelings mixed with guilt towards Jung-hwa and affection to her, Chul-min decides to play in the gambling fight abroad, which is the chance to collect the huge amount of money at once. He leaves her all at once without a trace or any note.
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http://ilove-koreanmovie.blogspot.com/2012/01/always-korean-movie-2011.html
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Herpesviruses are large DNA viruses that are highly abundant within their host populations. Even in the presence of a healthy immune system, these viruses manage to cause lifelong infections. This persistence is partially mediated by the virus entering latency, a phase of infection characterized by limited viral protein expression. Moreover, herpesviruses have devoted a significant part of their coding capacity to immune evasion strategies. It is believed that the close coexistence of herpesviruses and their hosts has resulted in the evolution of viral proteins that specifically attack multiple arms of the host immune system. Cytotoxic T lymphocytes (CTLs) play an important role in antiviral immunity. CTLs recognize their target through viral peptides presented in the context of MHC molecules at the cell surface. Every herpesvirus studied to date encodes multiple immune evasion molecules that effectively interfere with specific steps of the MHC class I antigen presentation pathway. The transporter associated with antigen processing (TAP) plays a key role in the loading of viral peptides onto MHC class I molecules. This is reflected by the numerous ways herpesviruses have developed to block TAP function. In this review, we describe the characteristics and mechanisms of action of all known virus-encoded TAP inhibitors. Orthologs of these proteins encoded by related viruses are identified, and the conservation of TAP inhibition is discussed. A phylogenetic analysis of members of the family Herpesviridae is included to study the origin of these molecules. In addition, we discuss the characteristics of the first TAP inhibitor identified outside the herpesvirus family, namely, in cowpox virus. The strategies of TAP inhibition employed by viruses are very distinct and are likely to have been acquired independently during evolution. These findings and the recent discovery of a non-herpesvirus TAP inhibitor represent a striking example of functional convergent evolution.
Citation: Verweij MC, Horst D, Griffin BD, Luteijn RD, Davison AJ, Ressing ME, et al. (2015) Viral Inhibition of the Transporter Associated with Antigen Processing (TAP): A Striking Example of Functional Convergent Evolution. PLoS Pathog 11(4): e1004743. https://doi.org/10.1371/journal.ppat.1004743
Editor: Kasturi Haldar, University of Notre Dame, UNITED STATES
Published: April 16, 2015
Copyright: © 2015 Verweij et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Funding: This work was supported by the UK Medical Research Council (MC_UU_12014/3 www.mrc.ac.uk to AJD) and the Netherlands Scientific Organization (NWO Vidi 917.76.330-1 www.nwo.nl/en to MER). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Competing interests: The authors have declared that no competing interests exist.
The family Herpesviridae emerged approximately 400 million years ago . The first members of the class Mammalia arose 200 million years ago, at around the time of the Early Jurassic period, and, since then, herpesviruses and mammals have coevolved and adapted to one another over very long periods of time. Today, members of the family Herpesviridae are numerous and widespread among not only mammals, but also many bird and reptile species; each virus displays a remarkable degree of host specificity. The longstanding interactions between virus and host have likely contributed to the development of the host’s innate and adaptive immune system and the mechanisms that viruses use to evade those systems.
The first line of defense against intruding pathogens is the innate immune system. This comprises the complement system, natural killer (NK) cells, apoptosis, pattern recognition receptor-mediated intracellular signaling leading to the production of IFNβ and many other cytokines and chemokines, and phagocytes like neutrophils, macrophages and dendritic cells. Together, these mechanisms enable the host to limit replication and spread of a pathogen and facilitate the induction of specific adaptive immune responses. The adaptive immune system includes antibody-producing B-cells, CD4+ T-cells that recognize antigens presented in the context of MHC (class) II molecules, and CD8+ T-cells that generally recognize antigens in the context of MHC I molecules.
During and following protein synthesis, a proportion of the resulting proteins is rapidly degraded into peptides by the proteasome. The resulting peptides are subsequently translocated into the lumen of the endoplasmic reticulum (ER) via the transporter associated with antigen processing (TAP) [2,3]. Within the ER, the peptides are loaded onto newly synthesized MHC I heavy chain / β2microglobulin (β2m) heterodimers. This process is facilitated by at least five ER-resident molecules that together form the MHC I peptide-loading complex (PLC). Tapasin functions as a chaperone, bridging MHC I molecules and TAP and catalyzing the binding of high-affinity peptides [4–10]. The lectin-like chaperones calnexin and calreticulin promote folding of newly synthesized MHC I molecules; additionally, calreticulin recruits the thioloxidoreductase ERp57. ERp57 and protein disulfide isomerase (PDI) are involved in stabilizing several protein-protein interactions within the PLC via disulfide bond formation [11,12]. Acquisition of peptide allows mature MHC I complexes to leave the ER, pass through the Golgi, and traffic to the cell surface where the peptides are presented to CTLs.
The family Herpesviridae is divided into the subfamilies Alphaherpesvirinae, Betaherpesvirinae, and Gammaherpesvirinae. Members of this family have been identified in many different species, including reptiles, birds, and mammals. There are nine herpesviruses known to infect humans: herpes simplex virus (HSV) types 1 and 2 (HSV-1 and HSV-2 in species Human herpesvirus 1 and Human herpesvirus 2, respectively, of genus Simplexvirus, subfamily Alphaherpesvirinae), varicella-zoster virus (VZV in species Human herpesvirus 3 of genus Varicellovirus, subfamily Alphaherpesvirinae), human cytomegalovirus (HCMV in species Human herpesvirus 5 of genus Cytomegalovirus, subfamily Betaherpesvirinae), human herpesviruses 6A, 6B and 7 (HHV-6A, HHV-6B, HHV-7 in species Human herpesvirus 6A, Human herpesvirus 6B and Human herpesvirus 7 of genus Roseolovirus, subfamily Betaherpesvirinae), Epstein-Barr virus (EBV in species Human herpesvirus 4 of genus Lymphocryptovirus, subfamily Gammaherpesvirinae) and Kaposi’s sarcoma-associated herpesvirus (KSHV in species Human herpesvirus 8 of genus Rhadinovirus, subfamily Gammaherpesvirinae) . Most of these viruses are widespread within the human population; for example, in the United States, approximately 90% of individuals of 80 years or older are seropositive for HCMV . VZV is even more abundant, with a seroprevalence of 95% in people from 20 years of age . Herpesvirus infections generally cause only mild symptoms, but in some circumstances they exhibit significant pathogenic properties, with the most serious complications tending to arise in immunocompromised people. Thus, HSV-1 can cause encephalitis, EBV and KSHV are associated with malignancies, and HCMV infection can result in congenital defects [16–18].
Following primary infection of their host, herpesviruses establish a state of latency in which viral protein expression is limited. As a consequence of this strategy, the virus-derived pool of potential antigens is minimized, thus hindering recognition and elimination of infected cells by CTLs and enabling the virus to persist for the lifetime of the host. In addition, several latency-associated proteins have been found actively to impede detection of virus-infected cells by the host immune system [19–21]. However, at some point, in order to disseminate the virus to other hosts, productive infection must occur. During this replicative or lytic phase, an extensive repertoire of herpesvirus-encoded genes is expressed in a kinetically regulated fashion. Depending on the virus in question, this results in the synthesis of at least 70 functional proteins, and renders the virus-infected cell susceptible to the memory immune responses that were generated during primary infection. Although these responses are instrumental in controlling infection and in limiting pathology, herpesviruses employ multiple evasion strategies to allow virus production in the face of existing antiviral immunity, thereby promoting spread within the host population.
In the past two decades, numerous articles have been published identifying and characterizing the immune evasion molecules expressed by herpesviruses. Most of these publications are focused on human herpesviruses, each of which has been shown to employ several strategies to interfere with the innate and adaptive immune responses. The MHC I presentation pathway appears to be a favorite target among the herpesviruses, illustrating the importance of CTLs in the elimination of virus-infected cells. Every step of this pathway is targeted by at least one herpesvirus. The availability of MHC I is affected by so-called host shutoff proteins that block cellular protein synthesis and thus expression of newly synthesized MHC I molecules. Examples of these proteins are the HSV-1-encoded vhs or UL41, EBV BGLF5, and KSHV SOX or ORF37 [22–26]. Additional strategies focus on inducing the degradation of MHC I molecules, as mediated by HCMV US2, US10, and US11 [27–29], murine CMV (MCMV) glycoprotein (gp) 48 , and murine gammaherpesvirus 68 mK3 [31–33]. Presentation of antigenic peptides by MHC I is also affected by HCMV US3 and MCMV gp40, which cause the retention of immature molecules in the cis-Golgi [34,35]. Finally, EBV BILF1 and KSHV K3 and KSHV K5 enhance the endocytosis of MHC I complexes at the cell surface [36–39].
In addition to strategies that limit the availability of MHC I, many herpesviruses affect peptide presentation by inhibiting the function of TAP. TAP is a heterodimeric ATP-binding cassette (ABC) transporter complex composed of two subunits, TAP1 and TAP2 (Fig 1). Both subunits are composed of an N-terminal transmembrane domain (TMD) and a C-terminal nucleotide-binding domain (NBD) exposed in the cytosol (Fig 1). The TMDs of TAP1 and TAP2 contain 10 and 9 transmembrane (TM) helices, respectively. The N-terminal 4 TM helices of TAP1 and the N-terminal 3 TM helices TAP2, known as TMD0s, act as autonomous interaction platforms for tapasin . Together with the NBDs, the C-terminal 6 membrane helices of each TAP subunit form the core of the transporter. Expression of this core region is necessary and sufficient for peptide transport .
Upper illustration: model of the TAP transporter, comprising the two subunits TAP1 and TAP2. Each subunit contains a transmembrane domain (TMD), encompassing 10 and 9 transmembrane (TM) helices for TAP1 and TAP2, respectively. The outer N-terminal helices of TAP1 and TAP2 (TMD0) form an autonomous binding platform for tapasin, whereas the core 6 TM helices are necessary for peptide transport. A peptide-binding domain is located within the cytosolic extensions of the TM helices. In addition, TAP1 and TAP2 contain a nucleotide-binding domain (NBD) in the cytosol, which harbors two ATP-binding sites. Lower illustrations: schematic representations of the interaction between the viral proteins and TAP. The sites where TAP is affected are indicated. HSV-1 ICP47 prevents peptide transport by physically obstructing the peptide-binding site. PRV, BoHV-1 and EHV (EHV-1 and EHV-4) UL49.5 leave the transporter in a transformation-incompetent conformation, thereby preventing the structural changes that are needed to translocate peptides over the ER membrane. BoHV-1 UL49.5 is known to interact with a region within the core domain of TAP, comprising the C-terminal 6 TM domains of both TAP1 and TAP2 . BoHV-1 UL49.5 induces the degradation of both TAP subunits, and EHV UL49.5 prevents ATP binding to TAP. HCMV US6 blocks TAP by inducing conformational changes that result in diminished ATP binding to TAP1. The protein interacts with TM domains 7–10 of TAP 1 and TM 1–4 of TAP2 . EBV BNLF2a inhibits peptide transport by interfering with both peptide and ATP binding to TAP.
TAP preferentially transports peptides of 8–16 amino acid residues in length, but can accommodate peptides as large as 40 amino acid residues, albeit with lower efficiency [42–46]. The exact location of the peptide-binding pocket remains unclear, but cross-linking peptide substrates to TAP and mutagenesis of TAP have shown that elements within the cytosolic extensions between the TM helices of both TAP1 and TAP2 are involved in peptide binding to TAP [47,48]. These findings are further supported by homology modeling of TAP based on the resolved crystal structures of other ABC transporters . Three cytosolic pockets formed by TM helices of the TAP core complex have been proposed to represent the binding site for the peptide substrates .
TAP-mediated peptide transport is energized by ATP hydrolysis at the NBDs, which harbor two functionally nonequivalent ATP-binding sites. These sites are composed of conserved domains within both subunits, including the Walker A and B domains of one NBD and a signature motif of the opposing NBD. The consensus ATP-binding site that includes the Walker A and B domains of TAP2 has catalytic amino acid residues conserved among ABC transporters. The degenerate ATP-binding site, which includes the Walker A and B domains of TAP1, has a number of noncanonical mutations that reduce its catalytic activity . Although ATP binding and hydrolysis can still occur at the degenerate site [51,52] only ATP binding and hydrolysis at the consensus TAP2 site is essential for completion of the transport cycle [50,52–54].
The crystal structures of several ABC transporters, trapped in distinct conformations, have been resolved [55–59]. These structures, together with biochemical studies on TAP itself, suggest that TAP transport occurs in sequential steps with extensive conformational rearrangements of the NBDs and TMDs, which depend on nucleotide and peptide substrate binding [60,61] (reviewed by ). In an inward-facing conformation, the peptide-binding pocket faces the cytosol and the NBDs are separated. At this stage, TAP is receptive to both peptide and ATP. The binding of peptide and ATP can occur independently and induces conformational rearrangements that partially close the NBDs. The NBDs are only fully closed when both peptide and ATP are bound. These conformational changes are relayed to the TMDs and result in an outward-facing conformation of TAP, thereby exposing the peptide-binding pocket into the ER lumen and allowing release of the peptide. Upon ATP hydrolysis, the NBDs dissociate and the TMDs rotate back into an inward-facing conformation . In this way, conformational changes driven by peptide binding, ADP/ATP exchange, and ATP hydrolysis at the TAP subunits lead to the transport of peptides into the ER lumen.
Cells that naturally or experimentally lack expression of functional TAP complexes show a dramatic reduction in MHC I levels at their surface and a substantial decline in CTL sensitivity [63–68]. Herpesviruses appear to have taken advantage of this extensive dependency of MHC I expression on TAP function by encoding viral proteins that specifically impair TAP-mediated peptide transport. This review focuses on the characteristics and evolution of herpesvirus-encoded TAP inhibitors and their orthologs.
Simplexvirus ICP47 Orthologs
The first viral protein found to inhibit TAP function was HSV-1 ICP47 (Fig 1). This protein acts as a competitor of cytosolic peptides for TAP binding, thereby limiting the availability of peptides in the ER lumen and causing subsequent retention of MHC I molecules in the ER [69–72]. ICP47 is expressed as a soluble, cytosolic protein of 88 amino acid residues. Mutational analyses have defined residues 3–34 as the functional domain responsible for TAP binding and inhibition of TAP function [73–75]. Charged residues within this domain are crucial for TAP inhibition, and might mimic the N- and C-termini of peptide substrates within the peptide-binding pockets of TAP . Once bound to TAP, the viral protein traps TAP in a conformation that differs from that of TAP in a peptide-bound state . In contrast to peptide substrates, ICP47 blocks ATP hydrolysis at the NBDs of TAP, which is normally followed by peptide binding, suggesting that TAP is locked in an inward-facing conformation [51,77].
Orthologs of HSV-1 ICP47 are encoded by HSV-2 and other simplexviruses infecting Old World primates, including herpesvirus papio 2 (HVP-2 in species Papiine herpesvirus 2) for baboons, simian B virus (SBV in species Macacine herpesvirus 1) for macaques, and simian agent 8 (SA8 in species Cercopithecine herpesvirus 2) for African green monkeys . Inhibition of TAP is conserved for HSV-2 ICP47, despite the relatively low amino acid sequence identity (44%) (Fig 2A) . The ICP47 orthologs can be divided into two groups on the basis of sequence similarities within the domain responsible for TAP inhibition, i.e., amino acid residues 3 to 34 [73–75]. HSV-1 and HSV-2 ICP47 are in the first group and share identity within this domain, and both are known to inhibit TAP (Fig 2A) . HPV-2, SBV, and SA8 ICP47 are in the second group. The sequences of the N-terminal domain of these proteins show substantial identity to each other and differ substantially from those of HSV-1 and HSV-2 (Fig 2A). SBV-infected cells were shown to display minor MHC I downregulation compared to HSV-1-infected cells , suggesting that the ICP47 protein encoded by SBV does not inhibit TAP. Given the similarities between the SBV, HPV-2, and SA8 ICP47 proteins, the HPV-2 and SA8 ICP47 proteins may also be unable to inhibit TAP, but data are not available. Thus, TAP inhibition may not be conserved for all ICP47 proteins. The fact that ICP47 is only encoded by simplexviruses suggests that this gene evolved after this lineage separated from the varicelloviruses (Fig 3). There is evidence supporting the view that the ICP47 gene arose de novo, rather than being captured from elsewhere, as is the case for many immune modulatory genes in herpesviruses .
A) simplexvirus ICP47 orthologs, B) simplexvirus (upper 5 lines) and varicellovirus (lower 12 lines) UL49.5 orthologs, C) cytomegalovirus US6 orthologs, and D) lymphocryptovirus BNLF2a orthologs. The alignments of predicted primary translation products were made using ClustalW, followed by manual adjustment. The number of residues in each sequence is shown on the right. Green highlights residues that are conserved in all sequences, and yellow highlights residues that are conserved in a majority. Bold N residues in US6 indicate potential N-linked glycosylation sites. An illustrationof sequence disposition is shown below each alignment, with approximate boundaries displayed.
The Bayesian tree is based on amino acid sequence alignments for six large, well-conserved genes, namely the orthologs of HSV-1 genes UL15, UL19, UL27, UL28, UL29, and UL30, and is derived from McGeoch and Davison . Assignments to genera and subfamilies are shown on the right. Abbreviations not mentioned in the text are: MDV-1, Marek's disease virus type 1; MDV-2, Marek's disease virus type 2; HVT, herpesvirus of turkey; ILTV, infectious laryngotracheitis virus; PsHV-1, psitticid herpesvirus 1; GTHV, green turtle herpesvirus; THV, tupaia herpesvirus; GPCMV, guinea pig cytomegalovirus; CalHV-3, callitrichine herpesvirus 3; AHV-1, alcelaphine herpesvirus 1; OHV-2, ovine herpesvirus 2; PLHV-1, porcine lymphotropic herpesvirus 1; HVS, herpesvirus saimiri; HVA, herpesvirus ateles; and RRV, rhesus rhadinovirus. Red, blue, orange, and green shading indicate viruses that encode the ICP47, UL49.5, US6, or BNLF2a TAP inhibitor genes, respectively, and corresponding coloring of virus abbreviations indicate viruses in which these genes have been shown to be functional TAP inhibitors. Light orange shading identifies all members of the Cytomegalovirus genus that have a US6 gene. Light blue shading indicates all members of the herpesvirus family that code for a UL49.5 gene that might be involved in chaperoning maturation of glycoprotein M.
Varicellovirus UL49.5 Orthologs
The second TAP inhibitor discovered within the subfamily Alphaherpesvirinae is the varicellovirus UL49.5 protein. The most extensively studied member is bovine herpesvirus 1 (BoHV-1) UL49.5. Unlike ICP47, UL49.5 does not affect the binding of peptides to TAP. Instead, the viral protein binds to the core region of TAP and impairs TAP-mediated peptide transport through two unique mechanisms. First, BoHV-1 UL49.5 inhibits the conformational rearrangements that usually follow peptide and ATP binding, as inferred from fluorescence recovery after photo bleaching (FRAP) assays . Using this assay, the lateral mobility of Green Fluorescent Protein (GFP)-tagged TAP can be measured in the ER-membrane. TAP mobility is affected by the conformational rearrangements that occur upon peptide transport. Upon active peptide transport, the mobility of TAP molecules is slower than that of inactive TAP . In the presence of UL49.5, these changes in lateral mobility of TAP, and thus conformational rearrangements, are halted . Second, BoHV-1 UL49.5 strongly reduces TAP1 and TAP2 protein levels by targeting both TAP subunits for proteasomal degradation (Fig 1) . Mutational analysis of BoHV-1 UL49.5 has attributed degradation of TAP to the first five N-terminal amino acid residues and the ultimate residues of the C-terminal cytosolic domain of the protein . Interestingly, UL49.5 without a C-terminal domain does not cause degradation of TAP, but retains the ability to inhibit peptide transport; this implies that the regions responsible for this effect are located in the transmembrane or ER-luminal parts of the inhibitor .
Orthologs of UL49.5, also known as glycoprotein N (gN), are present in all members of the family Herpesviridae sequenced to date. However, TAP inhibition by this protein has been found only among the varicelloviruses. The UL49.5 orthologs encoded by the varicelloviruses BoHV-5, bubaline herpesvirus 1 (BuHV-1), cervid herpesvirus 1 (CvHV-1), equid herpesvirus 1 (EHV-1), EHV-4, pseudorabies virus (PRV), and felid herpesvirus 1 (FeHV-1) possess the same functional properties as BoHV-1 UL49.5, causing a robust inhibition of peptide transport, thereby decreasing MHC I molecules at the cell surface [84,85]. Infections with UL49.5-deletion mutants of BoHV-1, EHV-1, and PRV have shown that UL49.5 is necessary and sufficient for TAP inhibition during viral infection in vitro . Surprisingly, UL49.5 expressed by the varicelloviruses VZV, simian varicella virus (SVV), and canid herpesvirus 1 (CaHV-1) are incapable of reducing TAP function . Thus, the capacity to interfere with peptide transport via TAP is a feature shared by a subgroup of varicellovirus-encoded UL49.5 orthologs.
The TAP-inhibiting UL49.5 homologs were shown to block human TAP as well as their natural host TAPs, indicating that the proteins target a highly conserved region within the TAP complex [84,85]. Each UL49.5 ortholog appears to utilize a distinct mechanism of TAP inhibition. The capacity to arrest the TAP complex in a translocation incompetent state is conserved for EHV-1 and PRV UL49.5 (Fig 1) and most likely for EHV-4, BoHV-5, BuHV-1, CvHV-1, and FeHV-1 UL49.5 . The EHV-1 and EHV-4 UL49.5 proteins were shown to interfere uniquely with ATP binding to TAP (Fig 1) . UL49.5-induced degradation of TAP1 and TAP2 is conserved for the highly related viruses BoHV-1, BoHV-5, BuHV-1, and CvHV-1, all of which infect ruminants, but not for EHV-1, EHV-4, PRV, and FeHV-1 UL49.5 (Fig 1) . The UL49.5 proteins interfering with TAP function show around 40% sequence identity (Fig 2B). Proteasomal degradation of the transporter is only induced by the ruminant-infecting viruses. The cytoplasmic domain of the TAP-degrading UL49.5 proteins contains two unique, consecutive lysine residues and an RGRG motif (Fig 2B). These lysine residues, although potential targets for ubiquitination, are not required for degradation of TAP . However, the arginine residues of the RGRG sequence appeared to be essential for this phenotype .
Based on current knowledge, the UL49.5 molecules are the only herpesvirus-encoded TAP inhibitors that fulfill a dual role in viral infection. Within the infected cell, UL49.5 forms a heterodimeric complex with glycoprotein M (gM) and guides proper glycosylation and maturation of this protein [86–88]. Cells expressing both BoHV-1 UL49.5 and gM show reduced TAP inhibition when compared to cells expressing UL49.5 only, suggesting that the interaction between UL49.5 and gM interferes with the capacity of UL49.5 to block TAP . However, UL49.5 and gM display differential temporal expression in the context of viral infection, with the appearance of UL49.5 preceding that of the late protein gM . This provides UL49.5 with an opportunity to exert its immune evasive effect early during infection. Conservation of both UL49.5 and gM in the family Herpesviridae indicates that the original role of UL49.5 was that of a gM chaperone, and that TAP inhibition by the protein evolved later within the varicellovirus subfamily, possibly in the BoHV-1 lineage after its divergence from the VZV lineage (Fig 3). Alternatively, it is possible that the TAP inhibitory function was gained somewhat earlier among the alphaherpesviruses, and lost in the VZV lineage, as VZV UL49.5 is capable of interacting with the TAP complex even though it does not inhibit its activity.
Cytomegalovirus US6 Orthologs
HCMV encodes multiple immunoevasive proteins targeting the MHC I antigen presentation pathway, including the TAP inhibitor US6 [90–92]. This protein impairs TAP function by interfering with ATP binding to the transporter (Fig 1). US6 specifically prevents ATP binding to TAP1, but stimulates ATP binding to TAP2 . This is in contrast with the normal pattern of ATP binding, which preferentially involves TAP1 . US6 alters ATP binding to TAP by inducing conformational rearrangements that are suggested to resemble TAP in an outward-facing conformation [77,95]. Rather than physically obstructing the ATP-binding site in the cytosol, US6 induces these rearrangements by interacting with the ER luminal loops of TAP1 and TAP2 . This observation is supported by data obtained with US6 truncation mutants, which shows that the ER luminal domain of US6 is necessary and sufficient for the inhibition of TAP [90,93].
Orthologs of US6 are only encoded by cytomegaloviruses infecting primates . The rhesus CMV (RhCMV) ortholog of US6 (Rh185) shares only about 23% amino acid identity but nevertheless reduces cell surface expression of MHC I molecules via TAP inhibition (Fig 2C). The ER-luminal domain, identified as the functional part of US6 [90,93], shows remarkably low identity between the two orthologs (Fig 2C). HCMV US6 is a member of the US6 gene family, which is presumed to have arisen through gene duplication of a captured gene. The original gene gave rise to a block of six contiguous paralogs (US6, US7, US8, US9, US10, and US11), all encoding loosely related type I membrane proteins. Both the number of genes in this family and their encoded sequences have diverged extensively among the primate cytomegaloviruses. For example, chimpanzee cytomegalovirus (CCMV) and HCMV both encode six homologous genes in the US6 family. In contrast, RhCMV and simian CMV (SCMV) each have five genes, with orthology to HCMV being more difficult to determine . Owl monkey cytomegalovirus (AoCMV) and squirrel monkey cytomegalovirus (SaCMV), which infect New World primates, have four and seven members of the US6 family, respectively. However, these are located in noncontiguous regions of the genome, and both viruses lack an obvious US6 ortholog. No US6 family genes are apparent in cytomegaloviruses of non-primate hosts, including MCMV and rat CMV (RCMV) . Thus, it seems that the US6 gene family probably evolved during early primate evolution, with the TAP-inhibiting function arising in the Old World primate lineage (Fig 3).
Lymphocryptovirus BNLF2a Orthologs
The gammaherpesvirus EBV codes for a lytically expressed TAP inhibitor, BNLF2a, that inhibits TAP by interfering with the binding of peptides and ATP to the transporter (Fig 1) [98,99]. Mechanistically, BNLF2a is thought to induce conformational changes in the TAP complex that prevent association of ATP and peptide, but the sequence of events preceding the block in TAP function remains to be elucidated. BNLF2a consists of a hydrophilic N-terminal domain and a hydrophobic C-terminal domain (Fig 2D). BNLF2a lacks an obvious N-terminal signal sequence but is membrane-integrated, nevertheless. The protein was identified as a tail-anchored transmembrane protein that uses Asna1/TRC40, among other proteins, for ER membrane insertion . This mechanism of localizing to membranes is unique among the known viral TAP inhibitors.
Orthologs of BNLF2a have only been identified in lymphocryptoviruses that infect Old World primates . The BNLF2a orthologs encoded by rhesus, chimpanzee, baboon, and gorilla lymphocryptoviruses (RLV, CLV, BLV, and GoLV) share 53%–62% sequence identity with EBV BNLF2a and display a similar disposition of hydrophilic and hydrophobic regions (Fig 2D). When expressed in isolation, these orthologs downregulate cell surface expression of MHC I molecules, indicating conserved TAP-inhibiting properties for BNLF2a proteins expressed by lymphocryptoviruses of Old World primates . No orthologs of BNLF2a have been detected in members of the genus Lymphocryptovirus that infect New World primates, suggesting that the BNLF2a gene was acquired after the divergence of Old World and New World primate lymphocryptoviruses (Fig 3).
Members of all three subfamilies in the family Herpesviridae appear to exploit inhibition of TAP-mediated peptide transport as an immune evasion strategy. The TAP inhibitors that have been identified so far exhibit substantial variation in structural characteristics as well as in mechanisms of action. Yet, despite their large diversity, all inhibitors have evolved to serve a common end: diminish the supply of viral antigenic peptides into the ER lumen in order to avoid elimination of virus-infected cells by MHC I-restricted CTLs, thus ultimately aiding virus replication and spread. The manner in which this has been achieved represents a striking example of functional convergent evolution, and identifies TAP as an Achilles’ heel of the immune system.
All of the TAP-inhibiting proteins described in this review are expressed early during the viral replication cycle [89,91,99,101,102]. For example, EBV BNLF2a is expressed during the (immediate-) early phase of lytic replication, but the protein levels are reduced at later times in infection when other EBV-encoded immune evasive molecules are effective [103,104]. Similarly, BoHV-1 UL49.5 is expressed with early kinetics, but remains present during the late stage of infection . This prolonged expression can be explained by the dual role that UL49.5 plays during viral replication: early in infection, in the absence of gM, it acts as a TAP inhibitor, while at later times of infection it also functions as a chaperone for the late, structural protein gM that facilitates cell-to-cell spread of virus . The early expression of herpesvirus-encoded TAP inhibitors ensures inhibition of the transport of viral peptides into the ER for MHC association shortly after initiation of virus replication, before abundant viral protein synthesis starts. In support of this reasoning, T cell recognition of antigenic peptides expressed early after EBV reactivation is restored in cells infected with a BNLF2a-deleted recombinant EBV . These findings further substantiate the contribution of the virus-encoded TAP inhibitors to immune evasion during infection.
Directly addressing the in vivo relevance of TAP inhibition for human herpesviruses is difficult, because of the restricted host specificity of these viruses. HSV is an exception to the rule, as this virus can productively infect mice. The functional relevance of ICP47 was addressed using a murine ocular infection model. Mice that received uniocular corneal infections with wild-type HSV-1 developed encephalitis and died within 12 days . However, mice infected with an ICP47 deletion mutant did not develop encephalitis, pointing towards a role for ICP47 in preventing the activation of CD8+ T cells that avert the development of lethal encephalitis . An additional study showed that in systemically infected mice, an ICP47 deletion mutant was also attenuated compared to wild type HSV-1. However, in mice lacking TAP, this phenotype was reverted in neuronal tissues, including the brain, suggesting that TAP inhibition is crucial for neuronal infection by HSV-1 . The role of ICP47 in these mouse models seems contradictory to studies showing that ICP47 fails to inhibit TAP efficiently in mouse cell lines [69,70,79,107,108]. The low level of inhibition observed in vitro may be sufficient to generate a phenotype in vivo. Alternatively, ICP47 may block in vivo CD8+ T cell responses by additional mechanisms. In vivo studies on all other human herpesviruses depend on humanized mouse models. The identification of functional orthologs of, for example, US6 and BNLF2a in the genomes of Old World primate-infecting herpesviruses offers new opportunities to evaluate their contribution to replication and spread of the viruses in vivo. RhCMV, which encodes functional homologs of HCMV US2, US3, US6 and US11 , has been used to study the role of these immune evasion proteins in vivo . RhCMV is known to be able to reinfect or superinfect its host, despite the presence of high levels of neutralizing antibodies and RhCMV-specific CD4+ and CD8+ T cells. However, rhesus macaques could not be superinfected by a RhCMV strain in which the genetic region encoding the US2, US3, US6, and US11 homologs was deleted. In contrast, the presence of these genes was not required for persistent infection of RhCMV-naïve hosts or for superinfection of macaques transiently depleted of CD8+ T cells. These studies indicate that impairment of MHC I presentation is critical for evading CD8+ T cell responses during superinfection by RhCMV, but not during primary infection .
The recent identification of the first viral TAP inhibitor outside the family Herpesviridae highlights the importance of targeting TAP function as a general viral immunoevasive strategy. Poxviruses, like herpesviruses, are known for their elaborate strategies aimed at evading the immune system. Cowpox virus (CPXV) is the first non-herpesvirus that has been found to encode a TAP inhibitor. This protein, CPXV012, is an ER-resident type II transmembrane protein of 69 amino acid residues that inhibits TAP through its ER-luminal domain by interfering with ATP binding to the NBDs of TAP [111–113]. A recent analysis of this gene in a range of CPXV strains has provided interesting clues as to the possible origin of the TAP-inhibiting capacity of CPXV012. It appears to have originated from a frameshifting deletion from a longer protein that possesses an extended ER-luminal region containing a C-type lectin-like domain [113,114]. The longer protein does not block TAP. The majority of the recently isolated clinical strains encode the shorter, TAP-inhibiting protein .
The identification of TAP inhibitors in herpesviruses and poxviruses suggests that DNA viruses in particular benefit from interference with TAP function as a means to evade CD8+ T cell responses. The absence of such evasion mechanisms in RNA viruses may in part be explained by the high mutation rate of RNA virus genomes, which allows for CD8+ T cell evasion by antigenic variation [115,116]. The generally lower mutation rate of DNA viruses may require alternative immune evasion mechanisms, including TAP inhibition. The relatively large genomes of herpes- and poxviruses have the capacity to accommodate dedicated immune evasion proteins that counteract the host immune response.
Apart from TAP, MHC I itself is also targeted directly by a wide range of viral proteins encoded by herpesviruses and poxviruses. Among the alphaherpesviruses, ORF66 of VZV binds to and accumulates MHC I in the Golgi compartment [117,118]. Several betaherpesviruses express proteins that induce degradation of MHC I via various pathways. US2, US10, and US11 of HCMV target MHC I for degradation via the ubiquitin-proteasome pathway [27–29]. MCMV-encoded gp48 and U21 of HHV-6 and HHV-7 mediate degradation of MHC I via the endolysosomal route [30,119,120]. The m152 protein of MCMV retains MHC I in intracellular compartments . Rhesus CMV protein rh178 inhibits MHC I heavy chain expression by preventing its co-translational insertion into the ER membrane . Also members of the gammaherpesvirus subfamily induce MHC I degradation using a variety of strategies. EBV-encoded BILF1 reroutes MHC I and targets it for lysosomal degradation [36,122]. MHV-68-encoded mK3 targets MHC I for proteasomal degradation , whereas kK3 and kk5 of KSHV degrade MHC I through the endolysosomal pathway .
In addition to herperviruses, poxviruses and adenoviruses also encode gene products that target MHC I directly. CPXV203 of cowpox virus and E3-19K of adenovirus both cause retention of MHC I in the ER [124–126].
The reduced overall MHC I surface expression induced by viral inhibitors makes cells more vulnerable for NK cell recognition. NK cells sense the lack of MHC I on target cells; this may result in a response depending on additional activation and inhibitory signals (reviewed by ). Herpes- and poxviruses use a variety of gene products to counteract NK cell responses. HCMV has been especially well studied for its ability to evade NK cell-mediated cytotoxicity (reviewed in ), but other herpesviruses and poxviruses also encode gene products to counteract NK cell-mediated cytotoxicity [129–131].
In conclusion, four classes of herpesvirus-encoded TAP inhibitors have been identified so far. These appear to be unrelated and to have been acquired independently and relatively recently during evolution, providing a powerful illustration of functional convergent evolution. In addition, poxvirus CPXV012 has been shown to code for yet another type of TAP inhibitor. Where in vitro and in vivo studies have been possible, they have demonstrated the significance of TAP inhibitors in the evasion of CTL recognition and replication of the virus in the face of potent immune responses. In addition to inhibition of TAP, MHC I function is inhibited by a large repertoire of unrelated viral gene products directly targeting MHC I, representing yet another example of functional convergent evolution. The acquisition of a wide range of unrelated proteins that interfere with MHC I-restricted antigen presentation highlights the importance of CTLs in antiviral immunity.
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How to Eliminate a Range of Carpets Stains With Ease?
There are various means of planning spaces; the most crucial being the ceilings and the floors. Be it offices or domiciles, carpeting in Sydney is fashionable. Likewise lots of people use different styles of false ceiling in the space also due to different advantages that it provides.
A floor of a given place is covered with carpet in this way that the whole area seems like being covered with one piece of carpet. This is actually the thought behind carpet flooring. Carpet flooring has changed into a preferred choice due to the following advantages:
Maintenance: The principal and most important basis for using carpet to protect the floors is simple maintenance. Wooden surfaces might chip off, get discoloured due to falling of numerous types of liquids and it is difficult to have them back to the initial texture. However, carpets must be vacuumed, and washed with bleaching agents and the carpet cleaners to get rid of stains. At the most, you might have to work with shutters to maintain the texture soft. So maintenance is simple.
Safety: There is also the question of safety. Should you lose your grip and drop an item made of glass, carpet flooring can save yourself it from breaking unlike wooden floors. Also, if young ones fall down, they will maybe not be hurt as the carpet forms a cushion.
Sound Reduction: Carpet floors assist in sound reduction as well. This can be a benefit in offices where there is constant movement. The trotting sound of heels, the activity noise of furniture and so forth. is paid off dramatically.
Warmth: Carpet flooring proves to be described as a good insulator. Throughout winters, when you want to be warm and cosy, carpets retains it warm making the temperature within optimum and snug and provide the best answer as they can lure in the air.
Now let's examine why fake ceilings are common too.
A false ceiling is just a level below the key ceiling of cement. Since there is a space between both of these layers, the air within gets trapped. Air being fully a bad conductor of heat doesn't enable the heat to move into the room or a workplace. This way, false ceiling really helps to reduce temperature throughout summers.
False ceilings are popular in homes and in offices. These are mainly popular simply because they help to conceal electrical wiring. People in offices do not like it when they are at work when the lights are on their face like position lights. They desire the environment to become well lit, the lights must be soft and soothing.
Fake limit proves to be considered a good sound absorber. False ceiling is generally used by people should they have a film place or great speakers inside their home. This can help to manage the light and also makes an ideal atmosphere for seeing a movie in the comfort of your home.
More information is available on this article.
Carpet Flooring and false ceilings produce a good feeling among corporate people and are incredibly appreciated in domestic in addition to corporate use. They add a touch of class to the setup and make the space search niche and classy.
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http://thecheapcarpetinginsydney.tripod.com/blog.html
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14872748
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Hottie In Boots
Hi hope you like what you see, were looking for no strings fun with other couples or groups,sorry no single of either sex, were in a beautiful part of the lakes and its a shame not to get out there n use all this space to have wild sex.
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http://www.worldwidewives.com/profile/lakescoupleforfun3/uploads/hottie-in-boots-173505/
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14872749
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“The Young and the Restless” Executive Producer Mal Young spoke about what we can expect for the surprise coupling of Ashley and Ravi during February Sweeps!
Ashley/Ravi: “Despite their differences, Ravi Shapur (Abhi Sinha) is enamored with Ashley Abbott (Eileen Davidson), and why shouldn’t he be? She’s an on-point and beautiful executive who knows how to take charge and that definitely has his attention. Ravi will contemplate taking a risk and try to grow closer to the boss he’s so smitten with,” said Young in the latest issue of “Soap Opera Digest,” (SOD).
This week’s spoilers reveal Ashley will reveal a new side of herself to Jabot app guru Ravi. We at Soap Cities (SC) wonder what could that be??? So far, we have seen Ashley be very protective of Ravi, especially when Phyllis (Gina Tognoni) tried to woo Ravi to Fenmore’s. Now that Jabot has a major non-controlling interest in Fenmore’s, it will be interesting to see how Ashley shares her Ravi with Phyllis! However, it is obvious to everyone (including Ashley) that Ravi has a big crush on his boss. How it turns out will be anyone’s guess. We are talking about a smart, nerdy engineer making moves on a very smart, sophisticated, seasoned–and very wealthy–woman! But we can’t wait to watch Y&R during February Sweeps to find out! We also applaud Y&R Executive Producer Young for casting a South Asian actor and bringing diversity to Genoa City. While the role may seem a bit stereotypical, it’s nice to see more shades of color on the show! Of course, we at SC are not surprised since Young was a former producer on the BBC Soap “Eastenders,” which reflects the diversity of working class England. Despite their cultural differences and age, we say they should go for it!
What do you think?!
Give us your input in the comment section below. Check back with Soap Cities for more Y&R spoilers, recaps, news, and fun! Follow us on Twitter at @soapcities, on Instagram at @soapcities, and come chat with us in our Facebook group. Catch “The Young and the Restless” weekdays on CBS.
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http://soapcities.com/2017/01/yr-feb-sweeps-ashley-ravi-bollywood-supercouple/
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14872750
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Bo Dietl, the flamboyant former NYPD detective and TV personality, won’t be allowed to run for New York City mayor as a Republican.
The city’s five county chiefs decided that Dietl, who is not a registered Republican, lacked backing for a waiver, called a Wilson Pakula authorization, that would allow him to run in the party’s primary to unseat Democratic incumbent Mayor Bill de Blasio, several of them said Wednesday. He would need at least three of the five party chairs’ nods for the authorization.
“He looks accident-prone. He stuck his foot in his mouth. He doesn’t have a filter,” said Adele Malpass, chairwoman for the Manhattan Republican Party.
Dietl told Newsday that he would run with the Independence or Reform parties, and predicted he would get more votes than the eventual Republican candidate.
Meanwhile, another GOP hopeful, real estate executive Paul Massey, said at an appearance in Howard Beach, Queens, with borough chairman Bob Turner that he is best poised to unseat de Blasio.
“I’ve been out there for 30 years, effectively being the mayor of New York,” Massey said. “Now, I officially want to be mayor of New York.”
Dietl shrugged at Massey’s candidacy, pointing to his residency north of the city until recently as a stumbling block.
“I call him white bread Massey from Westchester, who has a personality like a legal pad,” Dietl said, adding: “I will guarantee you, I will pull more votes than the Republican nominee will.”
Dietl was scrutinized in 2015 after a report that he had been awarded a controversial $24,000 contract to examine a possible merger of Hempstead and Freeport police into the county force — an idea neither department knew about. The county later refused to pay for the report, calling it “incomplete.”
In March, the Nassau district attorney’s office said it would not file charges in the case.
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http://www.amny.com/news/elections/nyc-mayoral-race-bo-dietl-can-t-run-as-republican-county-bosses-say-1.13563832
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14872751
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* Prices may differ from that shown
Chocolate trading company is a little company on-line catering to every type of chocoholic, young and old, fussy, unfussy and special dieted. They are listed at Shopsafe.co.uk and have on a Retailbest.com award for Quality. They also show a great interest in the environment and organic foods, and that is very evident in the webdesign and layout.
The range of goods are immense, with ranges of normal, special occasions, Alcohol-free, Chocolate truffles, Dairy free chocolate, Dark chocolate bars, Diabetic / Sugar free chocolate, Fair trade chocolate, Flavoured chocolate bars, High Cocoa Chocolate, Hot chocolate, Marzipan, Milk chocolate bars, Novelty shapes, Organic chocolate, Single origin chocolate, Soya lecithin free chocolate, Wheat & gluten free chocolates & White chocolate
Their gift range includes Champagne & chocolate selections, hampers, Gift boxes & novelty chocolate gift items.
~ Products, selection & pricing ~
I have to say I was immensely impressed by the range of chocolate products this company have to offer, and how simple and impressive their menu is to navigate. As a rule I have a huge problem finding suitable 'treats' for myself as dairy allergic person, many sites carry only Green & Blacks which if I am not careful can contain small amounts of dairy products, and although they have a few different varieties Green & Blacks is stuck more on the 'bar' type of chocolate. Now don't get me wrong, I like Green & Blacks, but it is more like the chocolate I bake with or treat myself too in a chocolaty moment through the supermarket, not exactly special like a box of chocolates! Many supermarkets also do 'Soya' chocolate; however I have found it usually over sweet and have a rather weird texture.
What initially struck me is that the dairy free range on offer are not just dairy free, they are organic! So far as to say the dairy free range is actually a brand called Booja Booja truffles. The last 2 times I have tried the Organic gourmet truffle selection box, containing the following:
"A fine selection of award winning, assorted chocolate truffles. Contains: Champagne truffles, Ginger wine truffles, Hazelnut crunch rochers, Espresso truffles and Cognac Flambed banana truffles. All dairy-free, wheat and guten-free, 100% organic and Non-GMO. Oh yes, also suitable for vegetarians & vegans! Organic chocolate as it should be." **
I have to admit these are absolutely gorgeous. If you can imagine a soft smooth silky inside, with a slightly firm shell coated in cocoa you are close! Unlike most dairy free chocolate I have tried they are of a wonderful texture, minimal bitter after-taste and a chocolaty hit that will certainly have you reaching for more, but only in a way that you will have a wonderfully smooth after-taste that will linger for quite a while.
The selection box is the biggest box in the dairy free range at 220g, and costing £10.95 (before postage) may seem steep, however absolutely totally worth it. All the Booja Booja chocolates come in recyclable round wooden box. So far as to say I have had 2 boxes so far (birthday & Christmas) and my partner has apparently bought me a 'surprise selection' (IE 2 of the single flavour truffle boxes) for valentines, I only know this because he asked for the web address and asked me what I would like!
They have an extensive range of gift packages as well as ranges for specialised diets and occasions. I have bought my friend Bouchon Superior Selection and a 'Chocoholics Heaven' birthday card which she absolutely enjoyed, especially as a chocoholic! They also packed in some brochures & catalogues which her partner has dubbed her 'porn' as she wont let him look!
The Bouchon Superior Selection (Bordeaux wine flavoured chocolates wrapped up to look like corks) and a 'Chocoholics Heaven' card cost £4.99 and £1.50 respectively, and the card can be printed inside for you for direct delivery to the recipient.
~ Delivery & Packaging ~
When delivered expect a rather hungry looking postman! The chocolates come wrapped in a recyclable cardboard box around 2 - 3 times the size of the actual contents you have ordered, however the contents are well packed in recyclable packaging. You will also notice a nice '2" x 3" sticker on the box labelled "The Chocolate Trading Company" - and that's what usually get s the Postie hungry! Apparently seeing my deliveries go through has prompted the local post manager to go order some too! I will say however it is so well packed you open the box to a waft of delicious chocolate air, which tends to make you dive in to find the chocolates!!!
~ Customer service ~
They have really lived up to their customer service award. They have prompt postage of their products, usually arriving within 5 - 7 days of the order (sometimes less). All emails/invoices are worded in a friendly non fussy clear and concise way giving you a huge sense that this is a company you can trust. They are also extremely polite over the phone.
~ Extras ~
The company currently run a affiliate program, and as such you may be able to get through some shopping sites like 'Freefivers.co.uk' to get some cash back on your order
~ Payment methods ~
This company takes most major credit and debit cards via a VeriSign secured SSL gateway. If however you wish to pay by cash, postal order or still feel you don't want to hand your card details over a website, you can phone, post or even fax your order by using their details on the customer info page of their website
Please note the ** section of quoted text is from the product description of their website
Stunning Chocolates!!!! You can buy all the finest chocolate from around the world, from vintage bars to stunning gift boxes, perfect for bithdays or when friends come round. My best buy yet, was the chocolate tasting discs for a dinner party, they even came with tasting notes so you can read all about them! They even sell an exploding chocolate bomb! Iam getting one for our next party, so I will let you know what happened!!! Delicious!
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http://www.dooyoo.co.uk/online-shops/chocolate-trading-co/
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14872752
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"So Sambo beat the bitch!”
This is how Republican Vice Presidential nominee Sarah Palin described Barack Obama’s win over Hillary Clinton to political colleagues in a restaurant a few days after Obama locked up the Democratic Party presidential nomination.
You can read the rest of this story at LA PROGRESSIVE.
I'd love to believe this isn't true but my gut tells me it is.
Hat tip to Karen at Namaste.
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http://midlifemutations.blogspot.com/2008/09/what-can-you-say-after-this.html
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14872753
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"My voice rises to God and I will cry aloud, My voice rises to God, and He will hear me" Psalm 77
My voice is so important to God. In the above Psalm David cries out to God to hear him and God does.
We've seen and experienced so much these past 17 days in ICU. We've seen people come in and recover. We've seen young and old pass away. Families crying and families relieved. Family and friends keeping constant vigil, or family and friends coming for brief moments. We've heard laughter and sobs. We are on that emotional roller coaster. There are highs and lows. Looking forward to the next high and yet always anticipating that dreadful plunge. We take nothing for granted. We constantly cry out aloud, "hear us, hear us".
Even now as exhaustion overtakes us, we don't ask why. We definitely have seen God using us in different ways. Each time He has called us to pray with strangers, we cry aloud hear us God let them see You, let them know You. Each time we tell a nurse, doctor or therapist that God is well pleased with the tender care they give Brooke for in His word He says "what you do to the least of His people He will do unto you". We see their eyes get teary, voices thanking us for that word from the Lord and we know seeds are being planted.
We see Him and feel Him here. Each day I pull myself out of bed and that tired feeling of "oh not again" comes over me I reach for his Word. Some times quickly, some times gradually He speaks "This is where I have you, look around, I am here and I want you to join me. I hear you". He hears me, He hears my annoying voice, my crying sobs, my laughter, and my torment - God hears me.
I am not super woman, I do have my moments of protesting to Him but He ever so gently and always so quickly reminds me that everything that is happening to Brooke has gone through His hands. He reminds me of all the other times He has heard me and answered me. The times He has cradled me in His arms. The times he has wiped away my tears and put them in a jar. The times He has given me new mercies each morning. He brings to my mind all of what He has delivered me from, all the comfort and peace He has lavished on me and the love He still gives to me even when I disappoint Him.
Even after all this I still cry out - Hear me O God - as if He needs reminding!
Brooke got to talk for the entire day! That is a miracle! She barely used the ventilator and we are thanking God for each of these precious gifts. Pray that the depression will subside and that God would send special angel friends to cheer her up and encourage her.
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http://tendergrassministries.blogspot.com/2011/06/hear-me.html
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14872754
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JO FOR GIRLS SILVER INITIAL PENDANTS
These lovely silver girls pendants in every letter of the alphabet make the perfect birthday gift for any young girl. Beautifully styled in their letter shapes they look beautiful on the neckline. Wear one for just the first name or two together for both initials. Hung on 14" silver chains and gift boxed.
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http://www.diamondkids.co.uk/brands/jo-for-girls/initial-pendants/
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14872755
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Family Friday - Woodcraft, Boats, and Brazilian Dancing Blowout!
July 28, 2017
11 AM - 12:30 PM
This summer, Family Fridays are hands on! Explore a different artistic material each week, with interactive artist demonstrations, exciting performances, and creations you can take home. Designed for a range of abilities and learning styles, Family Fridays take place in the E. Kendall Davis courtyard and include multisensory activities, picnic areas, and a Double Digit Clubhouse just for kids 10 and older.
Want a sneak peek at the new Tot Land? You won't want to miss our final Family Friday of the Summer! On July 28th, artist Martin Webb will be working in wood sculpture and painting, and everyone can join in! Martin is redesigning Tot Land in August* as part of Art Spots, which have been popping up all over the Museum this year. To finish Family Fridays with a blowout, the Mistura Brasileira Samba Dance Co. will bring a joyful show full of color, dance, and exciting Brazilian rhythms.
Originally from England but now a longtime Bay Area resident, artist Martin Webb makes artworks that include painting, sculpture, printmaking, and public art. He is represented by Vessel Gallery in Oakland and the SFMOMA Artist’s Gallery in San Francisco.
The Mistura Brasileira Samba Dance Co., based out of the Brazilian Center for Cultural Exchange, brings excitement and authentic Brazilian flavor to the Sacramento area. From the movements of the goddess, to the great influences from Afro-Brazilian culture, to the pulsating rhythms of Rio de Janeiro's Carnaval, Mistura Brasileira delivers a grand performance.
*Tot Land will close after August 13th and will reopen Sunday, September10th with a special Super Sunday Playday.
Free for members and free with general admission for nonmembers.
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https://www.crockerart.org/event/1305/2017-07-28
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14872756
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A bakery (or baker's shop) is described as an establishment that produces and sells flour-based food baked in an oven such as bread, cakes, pastries, and pies. We feel our bakery is so much more. It is a passion. We are all family and started out learning to bake from our mothers and grandmother. That is where the spark started, feeding family. The smell of warm bread baking, pies at holidays and cookies for any occasion. Grandma at 90 years old is still teaching us things. We want to carry on what we have learned by bringing you the experience of family in what we bake, the taste of home. Instead of telling you that we are gourmet and a taste extravaganza we want to tell you that we bake from the heart. Yeah we are professionally trained, but do you think that matters to Grandma?
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http://www.michigan.org/property/three-girls-bakery
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14872757
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Also, e.fault.getStackTrace() may come in handy...
No, its not in faultDetail either...
is that means faultEvent can not get message from server?
Does e.fault.getStackTrace() get you what you want?
If not, then I imagine you'll need to log/email the stack trace from the server side.
e.fault.getStackTrace() get stack trace of flex, but it doesn't help me, I don't need stack trace from server, I just want to display a returned message from server but I don't see any api in faultEvent can get this message
HTTP/1.1 503 Service Temporarily Unavailable Date: Wed, 27 May 2009 15:52:12 GMT Server: Apache/2.2.8 (Win32) mod_ssl/2.2.8 OpenSSL/0.9.8g mod_autoindex_color PHP/5.2.5 X-Powered-By: PHP/5.2.5 Set-Cookie: ZDEDebuggerPresent=php,phtml,php3; path=/ Expires: Thu, 19 Nov 1981 08:52:00 GMT Cache-Control: no-store, no-cache, must-revalidate, post-check=0, pre-check=0 Pragma: no-cache Status: 503 Service Unavailable Content-Length: 16 Connection: close Content-Type: text/html Invalide Version //<--a customized error message I want to simply display in flex
this is raw data of http response
I see the title of this post is confusing, it should really changed to "How can I get returned message from server in faultEvent listener"
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https://forums.adobe.com/thread/438755
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14872758
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(CNSNews.com) – Thousands of grass-roots conservatives streamed to Capitol Hill Thursday, heeding a call to action from Rep. Michele Bachmann (R-Minn.), who decided that speaking out was better than staying silent about the Democrats’ health care bill.
A steady stream of protestors toting signs reading “Kill the Bill,” “Free Healthcare Isn’t Free” and “No Obama Care” gathered at the West Front of the Capitol for the noontime “House Call” event.
As the crowd swelled, so did the ranks of Republican lawmakers, many of whom ended up joining Bachmann on the stage.
Bachmann announced plans for the rally – which she called a “news conference” – on Friday, Oct. 30. She told Fox News Channel’s Sean Hannity that the fight against the Democrats’ health care agenda was a pivotal moment in American history.
“That's why this is such an exciting opportunity for us,” Bachmann told Hannity. “This is about patriotism and manning up,” Bachmann said. “And if we can get Americans, literally by the busload, to come to Washington, D.C. next week, look their member of Congress in the eye, pay a house call on Congress and say, ‘Don't you dare take away my health care,’ cradle to grave. We'll stop this.”
House Minority Leader John Boehner on Thursday recalled the Sept. 12 “Tea Party” rally when hundreds of thousands of Americans rallied against the Obama administration’s fiscal policies, including the Democrats’ proposed health care bill.
“I'm going to stand with you and all freedom-loving Americans against this bill,” Boehner said, holding up the Constitution as he quoted from the Declaration of Independence.
“And I'm going to stand here with our Founding Fathers, who wrote in the Preamble: ‘We hold these truths to be self-evident: that all men are created equal; that they are endowed by their creator with certain unalienable rights; that among these are life, liberty and the pursuit of happiness.’”
House Minority Whip Eric Cantor (R-Va.) promised the crowd that “not one Republican” would vote for HR 3962 that was crafted by Speaker Nancy Pelosi and other Democrats behind closed doors. The bill may come to a vote as early as Saturday, if Democrats can get the 218 votes they need from members of their own party.
“As the Republican whip, I want to let you know that I have reached out to every Republican member of Congress in this House,” Cantor said. “And let me assure you, your efforts to stop this bill are being heard loud and clear.
“And I will guarantee you that we are committed to making sure that not one Republican will vote for this bill, Cantor said. “And with your help, we are going to try and pick up as many common-sense Democrats who will join with us, to stop this trillion-dollar takeover of our health care in this country.”
Rep. Mike Pence (R-Ind.), chairman of the House Republican Conference, recalled President Ronald Reagan’s stand on limited government.
“Twenty-eight years ago, on these historic steps, President Ronald Reagan said, we are a nation that has a government, not the other way around,” Pence said. “Now comes the Pelosi plan for a government takeover of health care. It's a freight train of runaway spending, bloated bureaucracy mandates and higher taxes, and it must be opposed.
“House Republicans are here to deliver a simple message to Speaker Nancy Pelosi and to the American people,” Pence said. “Madame Speaker, we the people are tired of runaway federal spending in Washington, D.C. And we the people want health-care reform that lowers the cost of health insurance, not grows the size of government.
“And to our fellow citizens I say -- those gathered and those looking on -- if you cherish freedom, if you fear the crushing weight of big government, and if you still believe that the strength of this nation is in the character and the courage and the ingenuity of the American people, this is your moment.
“Now is the time,” Pence said. “Let your voice be heard.”
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http://www.cnsnews.com/news/article/rep-bachmann-s-call-grass-roots-conservatives-fires-republican-lawmakers-too
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14872759
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Social media and recruiting is top of mind for many Recruiters and HR Managers recruiting through social media is one of the hottest and most discussed recruitment methods in the industry today. Recruiters have widely adopted social technology for their purposes of fulfilling recruitment needs. as the process of building connections comes naturally.
In Social Media Recruitment the recruiters engage with employees through social media to the resources for the job openings
The job openings posted on Social media not only helps in getting the required talent but also does the role of employer branding.
Many employers have social media sharing links to Facebook, Linkedin, Twitter, Google+ etc., though which there is an engagement build between potential candidates and their connections.
Social media recruitment and employer branding has now reached a stage where social recruiting isn’t just a novelty - it’s a must-have for any successful recruiting strategy.
The demand for Recruiters which knowledge of social media recruitment is also on a rise.
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http://www.equinoxes.in/training/social-media-recruitment.html
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14872760
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Your time is money. You are in charge of planning an event, whether the event is personal or professional it is a priority that it be unforgettable. You’ve got a budget to follow, deadlines to meet, a supervisor, a family member, or just yourself to please, and on top of all this, you’ve got your day to day responsibilities! How can you possibly do it?
How wonderful would it be if you could just tell someone what you want your dream event to look like and have it appear right before your very eyes? With our help, your dream can be realized.
The perfect event will secure a return on your investment, whether it is by pleasing your family members, raising funds for a non-profit, or advertising your services to a large group in a memorable way. Throughout the planning process you have the choice of how much involvement you want to have. Make the decisions you want and leave the details to us. Then on your big day…sit back and enjoy the spotlight knowing that behind the scenes we are coordinating every aspect to make your moment fabulous!
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http://www.eventsbymackie.com/home/maine-event-planner-why-hire-a-planner/
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14872761
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TEL AVIV (Jul. 24)
There is a reasonable possibility that the tens of thousands of immigrants presently in transient camps in Israel may receive permanent housing by the end of this year, Berl Locker, chairman of the Jewish Agency in Jerusalem, today told a Mapai meeting here.
He disclosed that the Agency’s expenditures this year would total 52 million pounds ($156,000,000) and that a large deficit was expected. He added that 40 percent of the Jews now arriving come from the Middle East and North Africa.
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http://www.jta.org/1949/07/25/archive/all-immigrants-in-israeli-camps-may-be-housed-permanently-by-end-of-year-locker-says
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14872762
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The 2017 Youth Conservation Corps program on the Shasta-McCloud Management Unit of the Shasta-Trinity National Forest is accepting applications for the upcoming summer season.
The 2017 Youth Conservation Corps program on the Shasta-McCloud Management Unit of the Shasta-Trinity National Forest is accepting applications for the upcoming summer season. This unique youth employment program provides an opportunity for young men and women of diverse backgrounds to work and learn new skills while participating in projects that enhance the development and conservation of the nation’s natural resources.
The 2017 YCC program begins June 26 and ends Aug. 11, and lasts seven weeks. Applicants must be 15–18 years of age; enrollees must be 15 by June 26, 2017, and cannot turn 19 during the program. The work schedule for selected applicants will be from 8 a.m.–4:30 p.m., Monday through Friday at the Mt. Shasta Ranger Station.
The crew members will perform natural resource based projects throughout the Shasta-Trinity National Forest. The enrollees will find the work difficult at times, but also extremely rewarding as they learn teamwork, techniques of proper hand tool use, and what it takes to be successful in the workforce. The enrollees will also enjoy educational field trips and a final graduation day at Lake Siskiyou.
Applications are available at the Mt. Shasta Ranger Station, 204 W. Alma St., Mount Shasta, CA 96067 and the McCloud Ranger Station, 2019 Forest Road, McCloud, CA 96057. Additionally, applications are available at the Mount Shasta, Weed, Dunsmuir, McCloud, Jefferson and Yreka high schools. Applications must be received no later than close of business May 5 at the Mt. Shasta or McCloud Ranger Stations. Enrollees will be chosen in a random drawing by members of the Mount Shasta community during a public meeting at the Mount Shasta Ranger Station at 10 a.m. on May 9. There will be a mandatory orientation for the chosen enrollees, alternates and their parents at the Mount Shasta City Park in May, date to be determined. Contact Program Coordinator Jon Dove at (530) 926-9653 or Marcus Nova at (530) 926-9606 for more information.
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http://www.siskiyoudaily.com/article/20170411/NEWS/170419944
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14872763
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The human eyes persistence of vision takes care of smoothing this anomaly apart from some situations like slow panning or spinning objects.
This is exactly the situation we TV salesmen have to explain to customers. I usually line up the customers in front of a 50, 100, 200 Hz machines, and ask them to weigh their differences. The price differences are immense. We have a pretty bad feed going through them, to see how good they are in making it better, in what is known as "upscaling".
What I find difficult to appreciate, is how some companies really try to validate their technology, when the primary difficulty, as the article clearly states, is source related. This problem is called Telecine, and all the manufacturers pretend they have sorted the problem out, when it is really being done by the eye itself. That causes more stress on the eyes in the long run. But what really annoys me is how Sony's PR pays sites to make it look as if the problem is solved, when it is not. Some sites at least have told the world that a lot of this is not to be taken too seriously.
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http://aligadgeti.blogspot.com/2009/05/human-eye-vs-telecine-judder-and-anti.html
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14872764
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When you think of seduction, what comes to your mind? If it's manipulation and black leather boots...you got it all wrong. Join me in my conversation with the incredibly Kitty Cavalier to discuss the art of sacred seduction and embracing your feminine power.
Disclaimer: Kitty pulled a fast one on me and started coaching me through my own intimacy and dating issues. And it happened before I even saw it coming. She's THAT good. But, I will always share what's going on for me and hopefully her coaching me through will help someone else with the sample complex.
So, what's my issue? I fear being a strong, motivated woman can be a turn off to men. And so I go after strong, confident men who can 'handle' me, but when I find those men, I feel I can't show my soft, feminine vulnerabilities. And then when I got the opposite route and find a sensitive guy, I lost all mojo and attraction.
It's a problem. Thank you Kitty for working me through.
For more on Kitty, check her out at kittycavalier.com. You can download the first chapter of her book 'Sacred Seduction' for free and get more information on her incredible group coaching program she mentions on the episode.
What intimacy issues did this bring up for you? How can you step more into your femininity? Let me know in the comments at catypasternak.com/thespiritualgangsterpodcast/24 or hit me up on social and let me know.
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http://www.catypasternak.com/thespiritualgangsterpodcast/24
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Size of this preview: 640 × 300 pixels. Other resolution: 320 × 150 pixels. Full resolution (download) (738 × 346 pixels, file size: 60 KB, MIME type: image/jpeg) About File History Metadata There is no description yet. Add a description. Appears on these pages of Custom '53 Chevy The Custom'53 Chevy debuted in the 2007 New Models. The Custom'53 Chevy has come out in the... Holiday Hot Rods Holiday Hot Rods are a series of Exclusive Cars, in Celebration for the Holiday Seasons that... File history Click on a date/time to view the file as it appeared at that time. Date/TimeThumbnailDimensionsUserComment current04:39, February 15, 2009738 × 346 (60 KB)Fantazim (Talk | contribs) Metadata This file contains additional information, probably added from the digital camera or scanner used to create or digitize it. If the file has been modified from its original state, some details may not fully reflect the modified file. Camera manufacturer PENTAX Corporation Camera model PENTAX Optio MX Exposure time 1/8 sec (0.125) F Number f/2.9 ISO speed rating 200 Date and time of data generation 01:22, November 22, 2008 Lens focal length 5.8 mm Orientation Normal Horizontal resolution 72 dpi Vertical resolution 72 dpi Software used ACD Systems Digital Imaging File change date and time 23:38, February 14, 2009 Y and C positioning Centered Exposure Program Normal program Exif version 2.2 Date and time of digitizing 01:22, November 22, 2008 APEX exposure bias 0 Maximum land aperture 3.1 APEX (f/2.93) Metering mode Pattern Flash Flash did not fire, compulsory flash suppression DateTime subseconds 609 Color space sRGB Retrieved from "http://hotwheels.wikia.com/wiki/File:08_Holiday_Hot_Ros_Custom_53_Wally.jpg?oldid=23959" Ad blocker interference detected! Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers Wikia is not accessible if you’ve made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected.
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http://hotwheels.wikia.com/wiki/File:08_Holiday_Hot_Ros_Custom_53_Wally.jpg
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Roller Derby is an American invention but leagues are booming across the Atlantic too. In this boisterous and rollicking half hour you'll hear from players like Auntie Terror, Anna Mosity, and Debbie Does Malice, and find what draws them to the skating oval to get bruised and battered. It's an exuberant celebration of self expression and female aggression.
Roller Girls was produced by Eleanor McDowall, and it was a Falling Tree Production for BBC Radio 4.
Ultraviolent Femmes vs Harbour Grudges
© Derek Bremner 2011
Note: This program originally aired on April 20, 2012.
Banner image © Derek Bremner 2011
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http://www.kcrw.com/news-culture/shows/unfictional/roller-girls
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Colin Jillings is travelling pretty well, and, after more than 50 years' training winners, why shouldn't he be?
He wears a horseshoe diamond ring given to him in 1970 by a "Yank horsetrader who went belly-up". He says he was going to sell it to get money owed, but didn't have to.
Jillings has flown over from Auckland with the final day of the Flemington carnival his target, hoping to win the Emirates Stakes (1600 metres) with a sore-footed five-year-old called Sedecrem.
Look closely at the name - it is Mercedes spelt backwards, and that is what Jillings is driving for the week he is here. It's a free ride, fixed up with a Melbourne yard by one of Sedecrem's owners - Ernie Ward, New Zealand's biggest Benz dealer.
It's a little incongruous in two ways, because Jillings says he drives a BMW in NZ and because he has to park this sleek vehicle at a dive of a place he is staying at - rugby followers and earlier arrivals at the spring carnival have taken the accommodation he preferred.
It is surprising that Jillings, who arrived on Sunday, and Sedecrem, who flew in on Monday night with strapper Adrian Reihana, sneaked under racing's radar.
This is one of NZ's top horsemen, who has brought to Australia horses such as Mr McGinty, Cox Plate winner The Phantom Chance and Tycoon Lil, who, Jillings says, unfortunately ran into Might And Power in the 1998 plate.
Sedecrem has won nine of 19 in NZ, the latest over 1400 metres at Avondale on Saturday.
"We're only hoping," Jillings says. But, rest assured there's considerable basis to that hope because the trainer doesn't travel if the horse is not a strong chance.
This brings us to stories of his coming to Australia in 1950, when Jillings took Lady Finiss and Gayriol to Sydney on the Wanganella.
They won four or five from nine starts, including one by 12 lengths at Rosehill. A younger Jillings celebrated - and paid for the few-too-many drinks when violently seasick on the rough passage home.
"Was I crook," he said this week, leaning on his borrowed Merc outside Chiquita Lodge at Flemington - he is staying with Mike Moroney at the same stables he used to land in when John Meagher had them.
Research indicated that Jillings did not "miss" riders when they did the wrong thing on his horses.
"You can tell these fellas, but you can't tell them much," he was quoted as saying when Shane Dye hit Tycoon Lil on the neck with the whip after being told not to.
And when Mr McGinty was beaten in a Melbourne race, Jillings gave Bobby Vance a hell of a bake. "Did I what," he recalled. "He got too far back.
"He was 25 lengths away, he was supposed to be lying third. He got within one-and-a-half lengths . . . but that's past tense."
More interesting were instructions to Vance when Mr McGinty raced against Marscay in the 1982 Todman Slipper Trial at Rosehill after winning five of six starts in NZ.
"Keep the little guy close to Marscay in the prelims," an NZ website quoted Jillings in a historical report, explaining the trainer's reason as "McGinty's price was sure to drift when the Aussies saw how small the horse taking on their champ was".
He got the money.
The concern with Sedecrem is his feet, Jillings saying the gelding had no sole and, touch wood (a tap of his head), the stable had him better than he'd ever been.
"It's a big ask, we're only hoping," was as close as Jillings went to tipping, but he insisted when The Age requested an interview that publication wait until weights were declared.
Sedecrem has 53.5 kilograms.
"I'm quite happy with that," was the response.
The horse will race at Flemington with Jillings as sole trainer - that's the Australian rule - but in NZ he has had a 12-year partnership with Richard Yuill at Takanini, near Auckland.
"He's been with me for 25 years," said Jillings in explaining the reason for the partnership. "I don't like to use people and I don't like to be used. It's a fair dinkum partnership - we're halves."
It is likely to continue only until November, 2005, when Takanini, which Jillings claims has the best training facilities in Australasia, closes to be redeveloped for housing.
"I'm too bloody old (to relocate)," said the 72-year-old. Yuill, 47, will keep training when Jillings retires with wife Alison, children and grandchildren.
He describes Sedecrem, known in the stable as Ernie after managing owner Ward, as being so quiet you could bring him in to your lounge.
He wants to take him further than that, however. The goal is to race over 1600 in Hong Kong in mid-December, depending on how Sedecrem shapes up in the Emirates.
Kerrin McEvoy will ride at Flemington because Paddy Payne, who rode Ultimate Aim for Jillings in the 1993 Melbourne Cup, cannot make the weight.
"I think the speed will be on," the trainer suggested. "I'd like him to settle fifth or sixth, but half the field will be trying to do that.
"I knew the opposition would be strong, but that's the chance you take. If you're frightened, don't come."
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Copyright © 2003. The Age Company Ltd
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http://www.theage.com.au/articles/2003/11/06/1068013326023.html
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I love cute and girly dresses, but on the other side, I also love, love men’s wear. I find them comfortable, and sometimes sexy. I also really love this pair of shoes I bought from Janilyn (okay, I’ll say it here: I love Janilyn, it’s my favorite shoe store). My mother laughed at me when I wore this because she said it reminded her of her grandfather.
How are your Christmas preparations? I’ve been doing some DIY decor in the apartment (be sharing them in the next posts). I’m wearing thrifted black blazer, thrifted shirt dress, sister’s bag, Juan by Janilyn shoes.
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https://thriftingadventures.com/2012/12/12/outfit-mens-wear/
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"I try to treat each day as editor of the Advocate as a gift. I thank the newspaper's owners, my co-workers and my community for their faith in me to do a job I consider central to society. While embracing the exciting opportunities presented by new media, I believe newspapers' future, whether in print or online, rests with the old-fashioned values of serving your community, creating meaningful connections, and trying to make a difference in our readers' lives.
We're all family, after all. A newspaper should be that close friend who cheers your successes, cries over your losses, and prods you to be better than you ever thought possible."
Read more about Chris here
Managing Editor for Content
“I like working at the Advocate because every day is different. I like being able to tell the stories of our community from fun light-hearted stories to sad life-changing stories to hard hitting-investigative reports every day for our readers to enjoy.
In my 30 years with the Advocate, no two days have been the same, which keeps my interest in my work fresh. Working with the staff to develop the stories and try new ways of presenting the news in print and online also keeps the job fresh. I enjoy picking up the paper in the morning or clicking on the online paper and seeing the work our talented staff has done to educate and entertain our readers."
Read more about Becky here
"For almost 170 years, generations of Victoria readers have trusted the Victoria Advocate to be their key source of information about the region. They have turned to the pages of the newspaper to learn about the world surrounding them during good times and bad. For that reason, the Advocate is part of the region's history, and I am honored to be a part of that long journalism tradition that began in 1846. I owe it to Crossroads readers and to my long line of newsroom predecessors to make sure that the stories we print in the Advocate are fair, accurate and timely."
Read more about Tony here
Copy Desk Chief
"I've worked in many capacities at the Victoria Advocate over the past almost six years, and I've enjoyed every minute of it. From being a reporter, to then being features editor and eventually delivery desk chief, the Advocate continues challenging me every day to be better than I believe I am. One of the best aspects of this job is hearing feedback from our community about how the newspaper is working in their lives - money can't buy that kind of feedback. Leading the delivery desk, which is made up of copy editors/designers, I've learned so much about copy editing and making writing tighter and better. As bad as it may sound, I enjoy finding errors prior to publication because it makes me feel like we're working that much harder and truly making the paper the best it can be."
Read more about JR here
"When I landed at the Advocate five years ago, I didn't expect to become so endeared to this paper. It's a newsroom like no other, one that allows journalists to freely pursue topics that interest them. We hear "Yes" around here more than we hear "No," which may be the reason a large number of reporters and editors, graphic designers and photographers from near and far want to work here -- there's freedom to explore the world and pen great stories. One of the most significant "Yes" moments I experienced here was in 2013, when my editors allowed me to travel to India for a month, so I could write about international religion and the blending of Western and Eastern cultures. But I've had the opportunity to accomplish many professional goals while working for the Advocate and I know I'm blessed to be part of this magical team. It truly is one of the best community newspapers in the nation.
I've always said that being a journalist is like having an all-access VIP badge to private details of people's lives. Somehow, being a member of the media allows us the rare gift of being able to ask the most intimate and personal questions to strangers and know there's an honest answer on the other end of the question. It's an honor and a privilege to be the person who gets to facilitate those special interviews and be trusted to write a story that makes a difference in the community. More recently, I've loved being part of the GC magazine team, overseeing many significant changes in its presentation and content as we push forward to a new era of GC. We are aiming to create a city magazine the Crossroads can be proud of, and dying to read each month. I believe are achieving that goal each month."
Read more about Jennifer here
"I'm one of eight children. My first name is pronounced (care-oh-lean-uh), but if you call me (care-oh-line-ah) I won't be offended. I graduated from the University of Missouri with a bachelor's in broadcast journalism and a minor in film studies. My work has appeared on the Associated Press, Studio 360, This American Life and BBC Americana. Before coming to the Advocate I worked for Minnesota Public Radio and Culturemap Houston. Got a story tip? Drop me a line at 361-580-6578 or email me at email@example.com."
Read more about Carolina here
Features Editor; Nonprofits/Health Reporter
"I love meeting people and telling their stories. Just finding people who genuinely care about the community and are passionate about what they do is what makes the long, crazy hours worth it."
Read more about Laura here
"I am fascinated by our judiciary and enjoy learning about and explaining its processes to our readers. I am passionate about holding those in public office accountable and giving a voice to marginalized people."
Read more about Jessica here
Courts/Public Safety Reporter
"Whether I am on the scene of breaking news or at my desk in the newsroom, I love my job because I learn something new every day. Reporting in the Crossroads has given me a unique chance to get to know one of the most vibrant communities in Texas firsthand. As a newly-settled Victorian, I promise to give my best effort in serving the area with accurate and timely information."
Read more about Jon here
I recently moved to Texas to cover local government from from Bend, Oregon, where I covered city government in one of the nation's fastest-growing metro areas. Prior to moving to Bend, I pitched and wrote stories for state and national audiences at the Associated Press’ Honolulu bureau as a temporary reporter. Before that, I wrote articles, produced multimedia and conducted data analysis as an intern at Honolulu Civil Beat, a watchdog news organization. I'm especially interesting in covering local politics, social issues and public health concerns. Please email me at firstname.lastname@example.org with any story tips or suggestions.
Read more about Marina here
"Reporting in the Crossroads is a new adventure each day, because I always learn something new about the community. I love being in one of the most unique places in Texas with so many people who have fascinating stories to tell. The best part is that I get to tell those stories. "
Read more about Kathryn here
"When I started my internship in April, I had no idea what to expect. I thought Clark Kent was going to turn the corner and people would be shouting deadline, deadline! I originally wanted to be a high school English teacher, however, I came to love what I was doing with my time at the Advocate. My passion for writing is why I am here. Gabriella Canales graduated from the University of Houston-Victoria with a B.A. in English in 2016. As the education reporter she will interested in covering all aspects and realms of education. Feel free to contact her with ideas because she is eager to tell stories."
Read more about Gabriella here
"Why do I like my job? I watch sports for a living --- what other answer is there? As for working at the Advocate — There's plenty: The ping-pong table in the break room; cake days; cool sports assignments; and most of all, working for and with people who care about our community.”
Read more about Alexandria here
"I enjoy covering events and keeping our readers informed about what's going on in area sports."
Read more about Mike here
"Writing about sports has always been my passion. Now, I get to do it alongside the most talented journalists in Victoria. The best part about my job is interviewing athletes after a game and seeing the excitement on their faces."
Read more about Rey here
"I have always wanted to cover sports since I was a little kid, whether it was reading a newspaper, watching television, or listening to sports talk radio. My family is from Victoria, Texas and it feels good to be back home covering teams that I have known about my whole life. The best thing about South Texas is the hospitality you receive going to each small town. Everyone treats you as you were part of their family. It’s great to see how much the sports scene has grown in Victoria and in the Crossroads. I’m excited to tell sports stories in the Crossroads.”
Read more about Marcus here
"Being a photojournalist is more than just a job to me. It’s a passion, a way to tell people’s stories, to document history, and to capture a certain moment."
Read more about Ana here
"Angela was born and raised in Phoenix, Arizona. In 2012, she earned a BA at ASU's Walter Cronkite School of Journalism and Mass Communication. After completing several multimedia internships she joined the Victoria Advocate team. Her hobbies include training dogs and roller skating. "
Read more about Angela here
Read more about Kimiko here br>
Senior Copy editor/Page Designer
"For me, having a hand in creating something that impacts people on a daily basis is what makes working at the Advocate so special."
Read more about Meredith here
Copy editor/Page Designer
"My favorite part of my job is getting people interested in a story they might not otherwise have read because of an exciting, eye-catching design."
Read more about Nicole here
Copy editor/Page Designer
"I love being part of the team that brings people their news. Whether it's laying out a big story or thinking of the perfect headline, there's always something interesting to do."
Read more about Sam here
"Being at the Advocate is rewarding and challenging -- something fresh and new every day. I enjoy being able to be of service to my community."
Read more about Kathleen here
"I like working at the Advocate because I like to know what is going on in the community and preserving its history."
Read more about Robbi here
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https://www.victoriaadvocate.com/staff/
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KEY MAKEUP ARTIST: Kiekie Stanners, Senior Artist M·A·C Cosmetics, New Zealand
INSPIRATION: “Next day beauty, with slept in eyes and sweaty skin. The Stolen girl has put on her glossy lip for the morning after”
Face: Strobe Cream to prep the skin. M·A·C Studio Waterweight SPF 30 Foundation and Studio Finish Concealer. Cremeblend Blush in Ladyblush applied on the lower apples of the cheek. Pigment in Naked and Vanilla applied to high points of the face with Cream Colour Base in Pearl and Gloss Texture.
Eyes: Pro Longwear Paint Pot in Groundwork buffed over eyelid and diffused into crease. Cream Colour Base in Midtone Sepia pushed into the lash line. Haute & Naughty in Too Black Lash. Eye Shadow in Omega to define brows. Pro Longwear Waterproof Brow Set in Quiet Brunette to add texture. Lips: Lip Pencil in Stripdown to outline lips. Lipstick in Myth and Lipglass in Clear. Nails: Studio Nail Lacquer in Skin.
PHOTOGRAPHY: Olivia Hemus for M·A·C Cosmetics
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http://apparelmagazine.co.nz/blog/2016/08/26/get-the-look-stolen-girlfriends-club-at-nzfw/
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It took me a long time to reconcile my palate with some staple American holiday desserts like pumpkin or sweet potato pies and pecan pie. As much as I love custards, pumpkin is not my go to for a satisfying slice of pie and pecan pie, the way I came to first know it, was a cloying, overly sweet and sticky mess I found downright abominable. The reason for it is that most commercial pecan pies are made with an ungodly amount of corn syrup and, regardless of which side of the fence you sit on when it comes to corn syrup, the end result in a pie is an unpleasant sweetness that overpowers the nuts.
As a pastry chef, I had to find ways to serve these desserts that were in line with my most basic baking principles (principle n 1: nothing should ever be too sweet). For years I made the pecan pies for my personal holidays with lovely Grade B Maple Syrup instead of corn syrup. The result is a marriage made in heaven but also terribly expensive as both pecans and good maple syrup don’t come cheap.
At work, I would add chocolate and bourbon – an adult version that sweet was not but still pleased the crowd. This year, I decided to eliminate the stickiness altogether and make my pecan pie with butter, honey, rum, chocolate and coconut flakes. Maybe not terribly orthodox but the Thanksgiving table deemed it so successful that only a few crumbs were left.
The crust was my tried and true crust, the recipe for which you can find here. If you are in a lazy mood, go ahead and buy a “fake” one from the store but, no matter how good, the difference between home-made and store-bought just cannot be bridged. Just saying.
The rest is as easy as pie.
RECIPE – Yields 1 10”pie
1 Raw pie crust, in a 10” pie plate
4 oz Butter (113 grams)
1/3 C Honey
2 T Heavy Cream
1/3 C Brown sugar (133 g)
1/4 C Coconut Flakes, unsweetened (30 g)
2 T Rum
1/4 C Dark Chocolate Chips
1 3/4 C Pecans (175 g)
Pinch of salt
- Line the crust with parchment and fill with pie weights then pre-bake at 325 F for about 15 minutes. Remove the weights and paper and finish baking for another 5 to 10 minutes, or until lightly golden. Let cool.
- Melt the butter. In a bowl, combine the butter, honey, cream, rum, sugar and a pinch of salt. Stir in the chocolate chips, coconut flakes and pecan. Mix to combine and pour in the cooled crust. The mixture will be fairly stiff and you might need to flatten it a bit with your hands.
- Bake at 325 for about 45 minutes or until the filling is golden brown and slightly puffed up.
- Let cool completely and serve with whipped cream (maybe spiced with more rum and/or cacao nibs)
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http://campariandsofa.com/2012/11/30/pecan-pie-season/
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The exact identity of Bu Halima is a mystery as not many details on her are present.
This name seems foreign amidst a long list of popular historical Mughal names. But then it is there, as an unusual tomb, a garden and a gate located on the western side of the beautifully well maintained Humayun’s Tomb Complex as a rectangular enclosure which is usually ignored by tourists and visitors as they pass by to see the more famous Humayun’s tomb.
A Prominent Woman In Humayun’s Life and Held in High Regard
However, Bu Halima occupied an important place in Humayun’s harem and was a part of Babur’s (Humayun’s father) entourage to India. It is said that she was Humayun’s wet nurse and also a Mughal noble woman. It is evident that she must have held an important position to have a garden named after her and to have her tomb placed barely 100 meters away from Humayun’s.
Unusual Placement and shape of her tomb without a dome
The tomb, however, is not placed in the centre of the garden, as is usually the case with most other tombs built during that period. This has led to the popular belief that the garden must have been developed before and the tomb was added later on (in other garden-tombs, it’s the other way round).
Unusual shape of her tomb without a dome is also a matter of intrigue where here Cenotaph lies exposed to open air and Sun.
Was it left unfinished like Nazaf Khans Tomb?
Bu Halima’s Tomb and Garden
Bu Halima’s Tomb
Today, the main entrance to Humayun’s tomb is through Bu Halima’s garden. The garden is simple and well-kept.
The rectangular enclosure of Bu Halima’s Tomb, contains a green, well-trimmed garden with a broad, neat pathway leading you in and out of it and another path (perpendicular to the main one) taking you to the structure on one end which contains the tomb of Bu Halima.
The architecture of this structure dates back to the early Mughal period. The tomb, rectangular in shape, seems to have been built with brightly coloured stones which appear to have faded over time.
Each of the four sides of the Tomb has two entrances carved out in them.
There is a staircase in front of this structure that leads up to its top. These stairs are not smooth and at the top, there is an octagonal platform. At the centre of this platform is where Bu Halima is buried.
Cenotaph of Bu Halima at the centre of an octagonal platform at the top of tomb
Bu Halima’s Gate
The West Gate, which is presently the main entrance to the tomb. The gateway is 16mtr high with rooms on either side of the passage on the ground floor and courtyards on upper floor.
Bu Halima’s Gate
Archival view of the 19th century, establishing notion of Humayun’s Tomb Complex being an ensemble of 16th century garden-tombs.
The profile of this arched gateway, together with the western enclosure wall before its demolition in 1916 is visible in the photograph taken by Samuel Browne from the roof of Humayun’s Tomb looking westwards.
Eons may pass, changes may occur but dust is always the destiny of all.
Compiled work from Internet sources
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http://madhukidiary.com/bu-halima-dust-is-my-destiny/
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21.02.2014 KNX Road Show South East Asia concluded with huge success
Today, KNX concluded its Road Show South East Asia with huge success in Kuala Lumpur. The first appearance of KNX in Malaysia included many events, such as a KNX Forum with 70 participants, a KNX Training Workshop with 40 participants, a KNX Device Development Forum and last but not least the foundation of the KNX Userclub Malaysia with already 10 members. At this point, we would like to thank everyone, who supported the KNX Road Show South East Asia. The market has proven its huge potential and there will be definitely coming more from KNX in South East Asia.
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https://www.knx.org/sea/news/KNX-Road-Show-South-East-Asia-concluded-with-huge-success/details.php?ref=36
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Paramore fans, of recent, have been waiting to hear news on the band’s latest music but will be forgiving of the band as they even announced Zac Farro has officially rejoined Paramore.
Farro’s return comes just in time too – the band are set to release their fifth studio album this year and fans will look forward to Paramore, once again, being whole.
Nickelback have announced the title of their newest album, it’ll be called “Feed The Machine” and the first single off the record – also called Feed The Machine” is one of their heaviest pieces of work since 2008’s Dark Horse album.
In their aforementioned latest single, they refer to a contemporary political leader as a “charlatan” but I’ll let touch decide who that’s about… If I were Nickelback, I’d be careful before Canadians are barred from a certain country.
They’ve also announced they will be touring North America with Chris Daughtry.
Foo Fighters News
Chris Shiflett, of the Foo Fighters, is releasing his first solo album later this year.
He’s put the first single, “West Coast Town”, on SoundCloud and it has a certain country feel to it.
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https://stevenjcarson.com/2017/02/07/paramore-as-strong-as-ever-nickelback-announcement-and-foo-fighter-going-solo-northernrock-newsflash/
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Dogs and Hogs After Hours to Support Macomb County Animal Control
Come join us at Wolverine Harley-Davidson for a night of food, drinks and live music benefiting the Macomb County Animal Welfare Fund. Your ticket includes access to the event, a drink voucher and a delicious meal catered by Vintage House! In addition there will be a 50/50 raffle and silent auction. Tickets are $30 in advance and $50 at the door with a special military rate of $20 a ticket if you buy your ticket before Sept 1st! All proceeds from this event will go to support the Macomb County Animal Welfare fund in saving homeless animals in YOUR community!
*This event is open to individuals age 21+*
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http://antonsowerby.com/blog/2016/09/02/dogs-and-hogs-after-hours-support-macomb-county-animal-control
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“The Adventures of Tintin” is all but certain to be nominated for Best Animated Feature at the Oscars. And with two-time directing champ Steven Spielberg helming this performance capture rendering of Herge‘s boy detective, it is one of the frontrunners to win. However, to prevail, it will have to overcome a strong challenge from “Rango,” which leads among our Experts, Editors and Users.
In the 10-year history of the category, seven of the winners were the biggest earners among the nominees while two of the other three made at least $200 million; only “Spirited Away” managed to win the gold without making much green. “Tintin” is likely to gross far less than most of the other nominees.
While “Tintin” has taken in more than $225 million around the world in the last six weeks, it has earned only $36 million since opening in the US and Canada last week. As the Christmas holidays can be a goldmine for kid-friendly films, expect that total to reach $60 million by Monday. How far it goes beyond that remains a question mark.
None of this year’s 17 contenders will top $200 million; the last Animated Feature winner to miss this mark was “Happy Feet” in 1996 which grossed $198 million. Five of this year’s films will make more than $100 million: “Cars 2” ($191 million), “Kung Fu Panda 2” ($165 million), “Puss in Boots” ($144 million), “Rio” ($144 million) and “Rango” ($123 million). “Gnomeo and Juliet” missed out by only $32,330 and “Alvin and the Chimpunks: Chipwrecked” is at $76 million after just two weeks.
All but one of the Oscar champs to date merited a Metacritic score of 84 or more; “Happy Feet” was at 77. None of this year’s contenders reached even that lower standard. “Rango” rated 75, “Arthur Christmas” came in at 69, “Tintin” totalled 68, “Kung Fu Panda 2” earned 67, “Puss in Boots” clawed its way to 65, “Rio” rounded up 63, “Cars 2” sputtered out at 57 and “Gnomeo and Juliet” managed just 53.
“Tintin” boasts an Oscar-winning duo behind the camera. Spielberg has Oscars for directing and producing 1993 Best Picture champ “Schindler’s List” and another for helming “Saving Private Ryan” in 1998. And producer Peter Jackson picked up three Oscars in 2003 for producing, directing and scripting “The Return of the King,” the third film in the “Lord of the Rings” trilogy.” When “Happy Feet” beat frontrunner “Cars” in 2006, part of that surprise success may have been due to the reputation of helmer George Miller.
Spielberg has another entry in this year’s derby. His live action film “War Horse” is a likely Best Picture nominee. If voters opt for another film for Best Picture, they may decide to give him the Animated Feature award as a consolation prize
While “Rango” won Best Animated Feature from both the Los Angeles Film Critics Assn. and the National Board of Review, “Tintin” was tops in Toronto. They compete at both the Critics’ Choice and Golden Globe awards as do “Arthur Christmas” and “Puss and Boots.” “Cars 2” vies only at the Globes while “Kung Fu Panda 2” contends for just the Critics’ Choice. If “Tintin” wins both of these precursor prizes, it would increase its odds of edging out “Rango” at the Oscars.
Studs don’t win Oscars
10 Golden Globe upsets that COULD happen
Gold Derby editors pick best and worst awards moments of 2011
Box office report: Meryl Streep has golden touch with ‘The Iron Lady’
Up close: See the Oscar ballot for Best Picture
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http://www.goldderby.com/article/2011/will-steven-spielberg-and-peter-jackson-be-good-luck-charms-for-tintin-at-oscars/
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14872777
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Slave . Puppet
Surrendering your power of choice to the Divine with complete trust.
Giving your willpower to an external authority out of fear of making your own choices
The Slave archetype represents a complete absence of the power of choice and self-authority. Yet it is precisely the absence of will power that gives the Slave its potential for personal transformation.
This act of releasing your will to a higher authority is also witnessed within organizational hierarchies, such as in the military and corporations. One becomes a Slave to the system.
For tens of millions of African Americans, the Slave archetype carries a historical freight that is impossible to overlook.
If Slavery is part of your genetic history, you need to take a close look at the possible presence of the Slave archetype in your intimate family.
Others who may dismiss this archetype as having no role in their life may discover that it is more prevalent than most people imagine, because of its many different expressions.
We don’t think of a soldier armed with weapons as a Slave, yet following orders unconditionally is an aspect of the Slave–especially when these orders personally violate your integrity.
The Puppet, for instance, may be manipulated by others.
The Shadow Aspect
The shadow Slave lacks the power of choice and self-authority, and follows orders that violate one’s integrity.
Do you have a history of becoming a slave to the system, or is slavery part of your genetic history?
Movies with Slave Archetypes
Watching movies related to one of your core archetypes, especially when going through the process of healing is a powerful tool to help you understand yourself (your motivations, your passions, your fears – why you behave the way you do).
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https://silvergirlshine.wordpress.com/category/the-slave-archetype/
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Seriously... How could you not tell? I mean, I've never seen a gay guy do something that gay.
I looked so gay, even Joy looked straight.
Hahahaha! The boy's have jokes!!
ok, so for those of us who are clueless, who got the helicopter ride and why?
trainwreck: that's all Joey, the pictured lam-o. But he killed his blog. Well, i think you can still find the pics. A few months back he bought a new MTB. Then crashed in Idyllwild. Then got a chopper ride. It was REALLY stressful for about 6 hours, then he walked out of the ER. http://freemanrace.blogspot.com/2008/09/aftermath.htmlhttp://freemanrace.blogspot.com/2008/09/what-week.htmlhttp://bikesbrosbrews.blogspot.com/Those should keep you entertained for quite some time!
Post a Comment
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http://joyonbike.blogspot.com/2008/10/new-bike-helicopter-ride-wearing-your.html
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14872779
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We were fortunate to have my sister and brother-in-law come down this week for a visit. Actually, the real reason they came was to take a load of our 'stuff' back to Cleveland. We had been going through and sorting things, so we had several boxes packed for them. We decided to take time on Tuesday and show them Chaco Canyon. It is a very fascinating place – highly recommended if you are ever in the area and it isn't raining. When we got home from there, we loaded up their little truck with the boxes, plus three more bins, and a bunch of odds and ends. You would think that should be the bulk of our stuff. Unfortunately, we still have a lot of go. The fun thing is going to be trying to find a place for it all when we get home.
They headed for home on Wednesday morning, and we picked up two ladies and headed for Holbrook to take them to the chiropractor. We enjoyed the ride down and back and the visiting with them. It was our Marys again, and they do make it a fun trip. The one told us that it was her birthday. So we fixed up a special treat and a gift for her when she came to Family Home Evening.
The Branch President called just as we were starting Home Evening and invited us to his place to help celebrate his son's 20th birthday. Definitely a night for treats and special birthdays.
We got to spend some time with our little Marianya this week. She is walking now. At Family Home Evening she walked back and forth across the kitchen many, many times. Then another day, it was across the front room, from couch to couch over and over again. It is fun to watch her. We have finished up the missionary discussions with her daddy, so we will see what happens now.
We have had our share of typical spring weather. It will be really warm and nice one day; then another day, there will be a hard wind blowing and several rainstorms throughout the day. Saturday, we woke up to a snowstorm. Course, when it started to warm up, it turned to rain. The District had planned a trip to the Toadlena/Two Gray Hills Rug Museum and Trading Post. The trader there shared his story of how he came to be at the Trading Post and other very interesting information about the area and the master weavers. One of the master weavers was demonstrating carding and weaving, It is neat to watch and see how they make their patterns in the rugs. That is something I don't think I could ever get the hang of; and yet, they make it look easy. Afterward, they fed us a delicious Navajo taco lunch.
We bought a rug the first time we visited, and the lady that wove it was working this time when we were there. So she found a rug that was similar to ours, and we had our picture taken with her. It was a cold, rainy day; but we didn't notice it because we were in the Trading Post. It was also a very enjoyable day. That was our last excursion with the Jensens because they are now short-timers.
Today we attended Seminary Graduation for the Gallup Stake. They had a very nice program, recognized the eight seniors that received their four-year diplomas, and the 44 other students that completed the course of study for the year. I have enjoyed being able to do Seminary this year and learned a lot about the Doctrine & Covenants. It has taken a lot of time to prepare the lessons; but it has been worth it.
When we weren't on the road, we were busy making visits and helping out the people in our area.
With all our goings and comings, you wonder when do we do missionary work? It is all part of missionary work for a senior couple. Their tasks are many and varied. Even within our District, each couple's missionary experiences will be different from another. We just take each day as it comes, and try to get as much done as possible before we call it day; and then we start all over the next day. Such is life in LA.
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http://olsenmission.blogspot.com/2015/05/werefortunate-to-have-my-sister-and.html
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Artist: Eric Sneo
Title: Out of Step
Release Date: 1st August, 2016
Cat #: TR217
01. Eric Sneo – Out of Step (Original Mix)
We are delighted to finally release Eric Sneo’s bomb track ‘Out of Step’. This track has been road tested by Christian at many festivals and clubs and we decided to release this track by itself as its strong enough. A big tribal groove, but modern sounding at the same time. This track rocks all the floors!
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http://www.differentgrooves.com/eric-sneo-out-of-step/
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The concept of machine is same with I-Shaped & U-Shaped straw wrapping machine.
This machine is designed to wrap the telescopic/periscope straw in OPP film and belt type packing.
The machine require two different diameter straw. One is for inner tube, the other is for outer tube.
The two straw tubes are automatically assembled and wrapped automatically.
Periscope straw : inner tube is straight ,outer tube is flexible
Telescope straw : both inner & outer tube are straight
Periscope straw manufacturing process
Extrusion - flexible machine - straw cutting machine - straw wrapping machine - winding packing
Telescope straw manufacturing process
Extrusion - straw cutting machine - straw wrapping machine - winding packing
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http://www.hellotrade.com/straw-pack/telescope-periscope-straw-making.html
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14872782
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Volunteer "astronauts" in a 500-day mock mission to mars have "landed" on the surface of the Red Planet, a major milestone in the project.
The Mars500 mission is a $15 million project sponsored by the European Space Agency (ESA), China, and Russia. Since June, the all male six-person crew has been sealed in a mock space ship at the Institute of Biomedical Problems in Moscow in order to study the psychological effects and technical issues of such a long space journey. The crew is made up two Russians, two Europeans, and a Chinese person, most of whom are doctors and engineers.
"This is the start of getting fundamental behavioral ecology data from long-duration confinement," David Dinges, a psychology professor at the University of Pennsylvania conducting a study attached to Mars500, told MSNBC. "It's a rare opportunity."
On Saturday, three of the crew members set foot on Mars, which is actually a large room in the institute outfitted with faux Martian rocks and dirt. They will spend 10 days on "Mars," and simulate three "Marswalks." The other three crew members will remain "in orbit." Mission control has communication glitches and emergency situations planned to gauge how astronauts would react.
"Mars500 is a visionary experiment," ESA's director for human spaceflight Simonetta Di Pippo said in a Space.com report. "Europe is getting ready to make a step further in space exploration: Our technology and our science grow stronger every day. Mars500 today is only an enriching simulation, but we are working to make it real."
Space.com said that the volunteer astronauts, who are actually getting paid about $97,000 to participate in the year and a half long project, have routines similar to that of real spacemen. They work on maintenance jobs and experiments, exercise daily, and have two days off every week.
The Mars landing is the halfway point of the project, which will conclude in November.
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http://www.pcmag.com/article2/0,2817,2380217,00.asp
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14872783
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Architecting a Website for the College of Engineering.
Research, User Experience
The College of Engineering at the Pennsylvania State University enlisted the help of Andculture to define an information architecture for all public-facing websites within the College. Our goal was to build consensus across the organization and identify and prioritize content that could be implemented by the College’s internal communications team.
We kicked off the project with a stakeholder workshop at the University. During this session, we asked stakeholders to write down primary audiences and messages on cards and prioritize them. The group’s collective contribution helped us establish a clear starting point and direction from the very beginning of the project. We spent the next three weeks conducting more than 25 interviews with professors, students, alumni, business partners and other staff throughout the College to understand the unique needs of each type of website user and potential use cases.
Synthesis is often a low-fidelity process that results in high-impact outcomes. Using a pinboard, we created a physical concept map to identify patterns and trends from our interview takeaways. This allowed us to collect insights and identify opportunity areas related to the website’s existing architecture and users’ needs. We used this synthesized information to determine which existing content to keep or eliminate, and where there was a need for new content.
Drawing from our synthesized research, we created site maps for each website type: College, department and center/office. Once the primary and secondary navigation levels were defined, we established the content hierarchy and weight within each section. The result was a collection of formalized information architecture diagrams that outlined a high-level sitemap and prioritizes the types of content within each section. Using the IA as a blueprint, we collaborated with the College’s creative director to wireframe VIP pages. The wireframing phase provided a clear hand-off between Andculture and the College of Engineering, as the final website was designed and developed in-house.
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https://andculture.com/work/penn-state
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While sitting at the church lunch tables on Sunday, my father started telling Lydia a story about his college days, his major, his trombone and low brass courses, and receiving an A from his professor. As much as Lydia HAD to be amused by the extremely interesting tale, someone else at the table was much more keenly aware of what Piano Man was saying. That listener was Brother Alan.
Now, those of you who know Piano Man are well aware of the fact that he's known for telling a story and repeating it and and then repeating it again - ensuring that everyone in the surrounding area has been able to fully appreciate the humor or interesting point of the story (if there is one.) However, that tendency still can't explain why Brother Alan felt the oddest sense of déjà vu while listening to Dad reminisce about his classes. Dad has never spoken to Alan about his college days. And, believe it or not, I don't think even I have witnessed the telling of that particular college memory. But, Alan - after reporting to work on Monday evening - still had goose bumps when remembering the Sunday event and told me he could have asked Dad to stop and taken over telling the story because the details were that clear in his "memory."
Since then, déjà vu (a.k.a. paramnesia) has been on my mind (when not thinking about heteronyms, that is.) And, I wonder if the preoccupation with the subject has caused me to fool myself because last night, when entering my house to prepare for the trick-or-treaters, I experienced the same type of chills that Alan experienced two days prior. (I almost always enter my house in the same way...but it was the feeling that I was entering in the EXACT SAME WAY...with the same purpose, with the same thoughts, with the same items on my steps, with the same items in my hands.)
I've discovered that the term "déjà vu" was coined by French psychic researcher Émile Boirac in his book, The Future of Psychic Sciences. It's translated as 'already seen', and it's that strange and eerie feeling that you've seen the exact same picture or situation before. And, scientific studies show that a little over 70% of the population have experienced it. (What's more fascinating is that almost 30% have not...or that many have experienced it only once!!)
Little did I know that there are three specific types of déjà vu:
Déjà vécu (translated 'already lived through'): the experience of déjà vu with more senses than mere sight, sensing great amounts of matching details from a "previous experience" (This is what most of us describe as deja vu.)
Déjà senti (translated 'already felt'): the experience of déjà vu as primarily a mental happening with very little memory or recognition of it afterward, with a trigger that will bring a recollection of familiarity to an individual
Déjà visité (translated 'already visited'): the less common experience of knowing a new place while knowing that there should be no prior geographical or spatial knowledge (This might happen when you are on vacation and have the feeling that you'll surely find a small church down the road on the left hand side.)
Here are a few other related terms that I thought were fascinating:
Jamais vu (translated 'never seen'): the experience of being in a situation that one rationally knows she or he has been in before while eerily sensing being in the situation for the first time
Presque vu (translated 'almost seen'): the sensation of being on the brink of an epiphany, often feeling like something is "on the tip of one's tongue."
L'esprit de l'escalier or l'esprit des escaliers (translated 'staircase wit', as in what you think of while on the stairs leaving a party): remembering something when it's too late, such as a clever come-back to a rude remark. (It seems I experience this even more often than déjà vécu!) :)
Have you had any occurrences with these phenomena that are still memorable to this day?
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http://stremmedout.blogspot.com/2006/11/dj-vu-dj-vu.html
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14872785
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"You can think you're dreaming if you like, it doesn't offend me. I often walk through dreams, so I don't mind. How would you like that? Walk through someone else's nightmares? I'm sure you could be good at it, you've caused enough of them. Lots more than me."
It was never like this, though. In dreams, women are nebulous. They're like smoke and softness and they're only as solid as desire.
Original Stories * Fanfiction * Articles * Reviews * Contact *
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http://kkeene.tripod.com/stories.html
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14872786
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Note: The below video is Not Safe for Work.
* Guatemala: Five Guatemalan soldiers were detained and accused of abusing their authority and mistreatment of minors after a viral video showed them brutally assaulting two teens.
* U.S.: According to the Labor Department the Latino unemployment rate last month is 6.8%, which represents a 0.2% increase from June but is a 1.1% drop compared to July 2014.
* Puerto Rico: Two major investors in Puerto Rico, OppenheimerFunds and Franklin Advisors, called on the commonwealth to make all of a $58 million debt-service payment that was due on August 3rd.
* El Salvador: Authorities believe that gang members were behind the deaths of four people riding a bus near San Salvador.
YouTube Source – user Criptograma MX
Online Sources – SunHerald.com, Reuters, Labor Department, Bloomberg
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http://ourlatinamerica.blogspot.com/2015/08/daily-headlines-august-7-2015.html
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14872787
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New 52 Comic Review – “Batgirl” #28
Sooo… Funny story.
That whole Gothtopia storyline? From last issue? That all takes place in other books. So, I still don’t know what’s going on in there. I guess I’ll do a recap once the story wraps up. For now…. We have VAMPIRES?!?
Okay. Why not?
In this issue, we add a new character to Batgirl’s cast. His name is Uchida, but he goes by Silver when he’s…
Gets brought a beverage and then is bathed by his female butler? No…
Hero-worships the villains of Gotham? No…
Oh, wait, here it is.
While he dons a Phantom of the Opera mask and practices opening fire on the Bat-Family with automatic weaponry.
So, cut to Barbara, running across rooftops and totally aware of the fact that somebody is following her.
She’s been trying to take out copycat killers, fans of the Brisby Killers from way back in the first issue.
But by the time she gets to ground level…
And she realizes who it must’ve been.
Of course, they do battle. Because using your words is only for toddlers and people in court-mandated anger management classes.
Now, remember, kids. Use your words. Because it turns out that Batgirl just punched a friend in the face.
Strix is a member of Birds of Prey, mostly because she’s dangerous as fuck and can be both trained as a hero and kept tabs on as a potential threat. She’s a threat because she’s a girl who lost her family, her ability to speak, her childhood, and then was “chosen as a Talon, an ageless, undead assassin, for the Court of Owls.” Luckily, Batgirl notes, she trusts her.
Babs asks her why she’s following her. Strix points to a lost child poster and Barbara assures her that the Gotham PD are actually pretty darn good when it comes to finding lost children.
Barbara asks why she insists that this become a Batgirl thing. Strix points out a part of the poster that points out that the missing girl, Cissy Chastain, cannot speak due to a childhood illness. She writes out for Batgirl that she’s a detective, that they’ll find the girl together, and that that’s why she didn’t want to contact the rest of the Birds of Prey.
Okay. Not exactly a reasonable explanation as far as not having several extra sets of eyes and their resources looking for a missing child. But whatever. Comics.
Barbara takes a sec to ziptie the crooks up for the cops before they set out. Apparently, though, her detective skills need some work because she misses some pretty glaring problems here.
Silver, meanwhile, is spying on the both of them. And this is what the scene looks like to him.
For some reason, Batgirl thinks that the best first option is to strike a deal with Knightfall. Just fucking right away. Before she’s even tried anything else.
Back in the alley, Silver does the knocked out gang members the favour of murdering them. Hooray!
At Barbara’s apartment, she’s got Strix looking through her closet for plainclothes detective type clothing. Strix immediately picks out Babs’ pink, frilly prom dress, clutching it to her chest like treasure.
They show up at the Chastain home to interview the missing girl’s mother. Babara uses a GCPD badge that she just “found” in the ladies’ locker room at the station. Because she’s a thief.
Anywho, the mother reveals that her husband disappeared some time back. Barbara thinks that the two events must be related.
But there aren’t a lot of leads, unfortunately, so Babs and Strix are back to hoofing it. But before they can hail a cab, and before Barbara can call her way too fucking needy boyfriend back, Silver shows up.
She plays dumb, and he waxes on about how the Bats are controlling the city, given free reign and owning towers and sewers alike. She asks him for clarification, kind of seeing where he’s going with this and concerned, but also seeing more than a little bit of crazy in this whole situation.
He claims to have killed dozens of her kind. Cue the fight scene.
This whacko is a whacko, but he’s also ready for her.
The police arrive and Barbara immediately assumes a protective, I’m-the-victim position, but it’s not 100% clear that she’s not going to be arrested.
Silver boasts, though, that he’s already won anyways. Because, you see dear readers, he’s captured the vampire queen. And strapped a bomb to her. And the bomb will go off at dawn and kill her.
Of course, the little girl is the vampire queen to this guy. Silver is totally going to turn out to be her dad and this is gonna be some kind of psychological thing where he blames her for the fact that his wife and his sex life never quite bounced back since before the pregnancy or some bullshit. Like that scene in “The Heat” but instead of soliciting a prostitute, the guy from “Arrested Development” designs an elaborate plot to assign classic movie monster personas and then murder them horribly. So… Well, note really like that scene in “The Heat” at all, then I guess.
Sooo, Awesome. Child abduction. Crazy people with delusions and hallucinations. And a bomb with a countdown of just a few hours. And a missing father somewhere in this whole mess.
So, I think that I’ve already mentioned that I hope that Batgirl is slowly going crazy. She’s a character that I can really see going rogue. I actually don’t think that anyone in the Bat-Family, and I mean really in the Bat-Family has ever become a real villain. Plus, she would make an incredible nemesis for virtually anyone in the DCU, but particularly for Batman. A true match. Because, yes, he’s outmatched her in the past, but she’s always held back. If she no longer held back, but he continued to do so (and we all know that he would still feel an obligation to her), she’d whoop his ass.
But I digress… Often.
I do hope, in the meantime, that she is arrested for being a part of this street fight. How is Barbara going to explain her mad skills, her appearance at the home of a woman whose daughter is the subject of a police investigation, and her possession of a GCPD badge and subsequently impersonating an officer?
That’s what I want to read about next week. Oh, and saving a young child’s like, too, I suppose.
See you then!
Posted on February 20, 2014, in DC Comics and tagged barbara gordon, batgirl, dc comics, gotham, gotham city, knightfall, new 52, silver, strix, vampire hunter, vampires. Bookmark the permalink. Leave a comment.
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https://thisfangirlsperspective.wordpress.com/2014/02/20/new-52-comic-review-batgirl-28/
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14872788
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As relatively new residents to Ticknall we decided to try out The Staff of Life for some pub grub. We were very well welcomed, lovely service by who I presume was the landlady, she was very attentive and friendly. The food was simply lovely, a good but not oversized portion and not to fussy! gorgeous.. think we wobbled rather than walked home!
- Official Description (provided by the hotel):
- In the heart of Ticknall, next door to Calke Abbey & Park. About 10 mins from Donnington Race Circuit, 10 miles from both Derby & Burton on Trent. ... more less
- Reservation Options:
- TripAdvisor is proud to partner with Booking.com, Travel Republic (UK) and Agoda so you can book your The Staff of Life reservations with confidence. We help millions of travellers each month to find the perfect hotel for both holiday and business trips, always with the best discounts and special offers.
- Also Known As:
- The Staff Of Life Ticknall, Derbyshire
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https://www.tripadvisor.co.uk/ShowUserReviews-g642233-d631694-r160737500-The_Staff_of_Life-Ticknall_Derbyshire_England.html
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Originally Posted by tigerdave714
Very nice Phantom JB. And I like that Timmy too (shhh don't tell anyone). Glad to hear that you still get down to play with 3EV as well. Rock on
**gasps** tigerdave likes a electro gun.
thats a really nice timmy, ninja style. i really whish i could buy a phantom. if i ever get some spare cash ill pick one up.
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http://www.spyder.tv/forums/showpost.php?p=666&postcount=11
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14872790
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Following are answers to frequently asked questions about Smart Charter Group, their application; the effects it would have on the West Kendall area and the zoning rules and procedures.
Q. Who wants to build the Charter School on 120th Street at 133d Avenue?
A. The applicant/developer is a Florida Company named Smart Charter Group, LLC, which was formed in July, 2014. It acquired the property which is the subject of their request in the same year. This company appears to be owned by two other Florida Limited Liability Companies: S.M.A.R.T. Management, LLC and MG3 Developer Group, LLC, both of whom list the same address: 1915 Harrison St., Hollywood, Florida. These two companies appear to be owned by the same three persons: Marcelo Saiegh, Hernan G. Leonoff, and Gustavo B. Bogomolni, all of whom list their addresses at 1915 Harrison St., Hollywood, Florida. These same gentlemen also own another Limited Liability Company at the same address called MG3 Fund, LLC, and one or more of them have interests in a number of South Florida companies which generally have “MG3″ as part of their name.
Q. Why does this matter require a hearing before the Miami-Dade County Commission?
A. Because the developers want the Commission to give them a “Special Exception” to the County’s zoning code to allow them to build a 3,000 student school in a “No School Zone.”
Q. What is a “No School Zone?”
A. The Miami-Dade County Zoning Code, Chap. 33, Art. XL, for safety reasons prohibits the construction of new residences, churches, places of public assembly and educational facilities in a safety zone extending 5 miles from the end of Tamiami Airport’s runways. The Code expressly created an “NSZ” (“No School Zone”) zoning classification which provides: “New educational facilities, excluding aviation schools, are not permitted within this land use designation.” The site on which Smart Charter Group, LLC, proposed to build its 3,000 student school sits within this zone. The BridgePrep school now existing on that land was granted a “variance” from that use limitation in 1979 because it pre-existed the NSZ restriction. BridgePrep is limited to 600 students by the existing variance.
Q. What is an “Aviation School?”
A. The Miami-Dade County Zoning Code, Sec 33-390, defines an Aviation School:
“Aviation schools shall mean any educational facility that primarily provides education or training in the science and art of flight, including, but not limited to: the operation and construction of aircraft, aircraft power plants and accessories, including the repair, packing and maintenance of parachutes; the design, establishment, construction, extension, operations, improvement, repair or maintenance of airports or other air navigation facilities, and instruction in flying or ground subjects pertaining thereto.”
Q. Is the Charter School proposed by Smart Charter Group an “Aviation School?”
A. The SOS120Street Committee believes it is not. There is nothing in the application, or the architectural plans submitted with it that evidences specialized classes, workshops or facilities designed for flight training; airframe or aero engine maintenance; airport maintenance or design or parachute packing. There is no commitment in the application regarding the hiring of instructors in these fields. There is no showing the applicant or its principals, teachers or employees have any experience or history in these fields.
The ordinance defines an “Aviation School” as one that primarily provides aviation-related training. Over 40% of the projected enrollment will be K through 8. The Committee believes it is unlikely an aviation related curriculum can be developed for students so young, and that the sole reason the zoning application refers to an “Aviation Charter School” is to get the zoning application through the “No School Zone” exception.
Q. What is the SOS120Street Committee?
A. It is a committee made up of the residents of the neighborhoods closest to the proposed location of the school on SW 120th Street and what would be SW 133d Avenue. However it has members and volunteers from all over the West Kendall area. We are all affected by the present traffic overload and will all suffer by the increased traffic burden the 3,000 student school will create. SOS 120 Street, Inc., was created by the Committee to raise the funds and pay the costs necessary to oppose the Smart Charter Group’s requested Exception.
Q. Why does the SOS120Street Committee oppose the school expansion.
A. There are safety and traffic issues. There is a reason why there is a no school zone and limits on new home construction in airport landing zones. They are dangerous. Tamiami Airport is one of the busiest general aviation airports in the country. General aviation airports handle all kinds of aircraft, of all ages and conditions, flown by pilots with all kinds of experience – and inexperience. This includes student pilots.
Then there is the traffic. Everyone who lives near, or commutes on roads from, Southwest Kendall is aware of the overwhelming amount of local and commuter traffic that uses the East/West streets and roads in our area, especially during the morning and afternoon rush hours. The traffic not only causes gridlock on SW 120 Stree, but commuters trying to avoid it also jam SW 112th, 104th, 88th (No. Kendall Drive) Streets and shortcuts through local neighborhood Streets. The Smart Charter Group’s own traffic study (required for its zoning application) says this school will generate 7,400 car trips per day on 120th street. Much of it will be during the peak morning commuting hours. The traffic study is part of the public application and can be read in full on the County web site, referred to at the bottom of this page. The Miami-Dade Police Department Review of the zoning application says:
The existing traffic conditions in the area and surrounding roads are already overtaxed. The current configuration will expose the area to an increase in the existing excessive traffic during peak times and the lack of adequate egress and access to and from the school onto arterial roadways will require law enforcement intervention in perpetuity to facilitate the movement of said traffic. As such, the Miami-Dade Police Department objects to any proposed zoning modifications to complete this project.
Q. What is the present status of the Smart Charter Group’s application for the Zoning Exception?
A. The application, including its supporting documentation, and reports and comments by all relevant County departments, is presently before the Miami-Dade County Commission awaiting the public hearing required by State and County Law. The County has asked for additional documentation from the applicant. No final hearing date has yet been set.
The entire zoning application, with exhibits, is on line at the Miami-Dade County site: www.miamidade.gov/rer/track/case_track.aspx
Once at that site you can type in the name of the applicant: Smart Charter Group, LLC or type in the Process number: Z2016000020
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http://sos120street.org/index.php/faqs/
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14872791
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Bravo Supermarket is a chain that operates in various locations, mostly in the northeastern United States, including New York, New Jersey, and Connecticut. They also have several locations in Florida. They sell an array of products including fresh produce and cater to much of the Latino population.
The Bravo group was founded in the early 1990’s and they wanted to bring the New York shopping experience to those in Florida. Whether this was because a lot of people from New York moved to Florida and the company wanted to give them a taste of home, or whether it was because New York is the shopping capital, therefore a New York shopping experience is a powerful statement. They worked together with their already established sister company, C-Town Supermarkets.
The fourth and fifth stores were opened in Orlando as opposed to New York. At the time, Orlando was flowing with Hispanic New Yorkers, therefore the company was already known by many people and targeted at the Hispanic market. For these reasons, the store was an instant success and paved the way for several more to be opened. If you walk in to one of these stores, you can shop for Goya beans, listen to Latin music and see potted palm trees.
Sixteen stores in total were opened across Florida, briging authentic Hispanic ingredients to the community. This would not have been possible if it was not for Krasdale, the supplier, agreeing to supply their produce outside of New York. The stores range from small stores at 7,000 square fee to much larger stores at 25,000 square foot. This means that the stores are sized between the tiny bodegas’ in the area and the giant superstores.
In 2008 a branch opened on the northside, because they took advantage of the gap in the market for a good supermarket with an inbuilt pharmacy. Other services that this new store offered include custom cuts of meat, a deli and a department full to the brim of fresh produce.
The company’s customer service team can be contacted at the company headquarters at the following address: 65 West Red Oak Lane, White Plains, NY, 10604, U.S.A. Other important statistics about the company can be found listed below:
Ownership: Alpha 1 Marking Corporation
Public / Private: Private
Number of Stores: N/A
Number of Employees: N/A
Annual Revenue: N/A
Geography: North Eastern and Southern United States
Demographic: Value Shopper
Special Services: N/A
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http://www.grocery.com/bravo-supermarket/
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The hum you have picked up in your sub is probably a ground loop from the offset differential of the ground planes between the amp and the sub. These can be difficult to resolve. Might try lifting the ground on the amp and see if it goes away (or sub.)
Sometimes, the ground differential can be enough to cause such a reaction by the amp. However, my gut tells me your amp has a problem. I would pack it off to a service center for a check. NAD equipment is decent but historically, it has been known to have some issues. This series is no exception.
The NAD is certainly robust enough to drive the Totem's. Even though the speaker has a relatively low impedance in a narrow range (3.8 ohms) it is not that hard of a drive due to the speakers phase angle performance. Any decent amp should work well with these speakers.
Thank you Bigtee....I am not ignorant but certainly technologically challenged. How does one lift a ground? I will embarrass myself by inroducing a question whose answer is no doubt known to many, if not most! Thank you...Joseph
Easiest way is to use a cheater plug ... 3 prongs to 2 prongs plug.
Rar1, thank you. Believe it or not, that is what I thought but I wouldn't attempt that without the assurance from someone like yourself. Thank you!
Are you running the REL through the low level or the high level inputs?
Wow, I was going to say the suggestion that the NAD can't handle the Totems is ridiculous. Something else is going on there.
I'm not positive the NAD uses a 3 lug connector (some NAD amps don't) but if it does, use the cheater as Rar1 suggests and see if the hum goes away.
If the NAD does not use a 3 prong connector, use the cheater at the sub power cord.
Another trick is to use a small gauge wire connected from the chassis of the NAD to the sub amp chassis. It may have a ground lug on the sub-not sure as I'm not familiar with this brand. Worth a try.
As for your amp going out on protection, is it both channels or one channel? If both, I would suspect something in the power supply of the amp. This would require a visit to the shop for correction.
Could the protection circuit activating be caused by excessive heat? A basic question, but I must ask if there is plenty of room around the NAD, top and both sides? Is it in a cabinet?
"I recently placed a posting regarding the protection circuit activating on my NAD C375BEE running Totem Model One Signature speakers."
"The REL developed a hum when I introduced the NAD into my system. Coincidence or related to my problem? "
Is the protection circuit activating on the NAD, as well as having the hum from the sub?
It would seem to me that you have two issues here; perhaps they are related, but it is also quite possible that they are not related. The first thing I would do is isolate the two conditions (protection circuit and hum) by completely removing the sub from the system. Secondly, I wouldn't consider it a forgone conclusion that the amp is damaged just because the protection circuit is activated, especially if you powered off shortly afterwards.
I have the 375 also, and I think it to be a fine amp capable of driving just about any speaker. I find it puzzling that some would suggest it isn't robust enough. That just doesn't seem to be a rational suggestion; clearly information is missing somewhere.
When the sub is completely disconnected from the amp (all wires and interconnects removed), is the protection circuit still activating? If so, the next item to examine is the connections to the speakers. The 375 has two sets of speaker posts (A and B). Are you using only one set (A or B) of speaker posts or are you using both speaker posts (A and B)? If using both, what speakers are the second set of posts connected to?
On the back of the amp, I prefer the soft clipping be turned off but this is just a matter of preference. Also, the amp should be set to stereo. One more idea: there is a fuse with access from the back of the amp. You may want to pull the fuse out and take a peek at it. Perhaps the fuse is blown. Keep in mind a blown fuse is a symptom, not the cause. You will still need to trouble shoot to determine what caused the fuse to blow.
If the protection circuit is not activated when the sub is completely disconnected, then there is a problem with the way the sub is hooked up and connected to the amp.
We can give more specific help once we have a better idea how the amp performs independently and without any sub connected.
Pgawan2b, I do think you are offering good advice, however, the part about looking at the fuse makes no sense. That is an AC power fuse, so if it is blown, the unit will be totally dead and not work. The unit works, but with the protection circuit activating prematurely.
It looks like the OP started a thread at Audioholics at the same time, it's about the NAD C375, Totem Ones as well with the NAD protection circuit activating too. Later on in that thread, he adds that his previous integrated, an Anthem 225, had issues too. One speaker was much quieter so he had to adjust the balance knob and decided the Anthem was going and bought the NAD.
Now the NAD needs the balance adjusted too, but it's shutting down as well. Anyway, it's all there in the thread, 2 capable guys are helping him and they think the Totem ones or the sub is damaged.
Tls49, good point and thanks for the correction.
A number of good comments and suggestions have been provided above. I'll add one further thought while awaiting feedback on what has been suggested:
Are you certain that the two speakers are connected with the same phase, i.e., that + and - are not interchanged in the connections to ONE speaker?
If the two speakers are not connected in phase with each other, some of the results would be vague and diffuse imaging, and weak bass. I'm thinking that in some circumstances a result might also be the channel imbalance you have perceived, and also a perceived reduction in volume (which would be further compounded in one channel by the balance control offset). If so, to achieve reasonable volume and bass perhaps you are turning the volume control up high enough to overload the amp, with the clipping distortion that would normally result from doing that perhaps being prevented by the amp's soft clipping feature and/or by the amp's unusually large dynamic headroom.
Also, as Pgawan2b suggested, verify that the bridged mode switch on the rear panel is set to off/stereo. If the speakers are connected as a normal stereo pair but that switch is set to bridged mode, it would cause similar effects to those I described above for an out of phase speaker connection.
One more thought: Make sure that the black wire from the REL is connected to one of the negative (probably black) speaker terminals on the amp, and not to one of the positive (probably red) speaker terminals. If the black wire is interchanged with either the red or the yellow wire from the REL, and is connected to a positive speaker terminal on the amp, I believe that could account for all of the symptoms you have described here and in the other thread that was referenced above, and (consistent with what you have reported) could result in the amp shutting down even if the sub is turned off.
"Are you certain that the two speakers are connected with the same phase, i.e., that + and - are not interchanged in the connections to ONE speaker?
If the two speakers are not connected in phase with each other, some of the results would be vague and diffuse imaging, and weak bass. I'm thinking that in some circumstances a result might also be the channel imbalance you have perceived, and also a perceived reduction in volume (which would be further compounded in one channel by the balance control offset)."
That could be the problem. If you play a recording that normally has a solid center vocal image, wiring the speakers out of phase with each other will make the vocals sound like they are coming from one of the side walls, and not the center. Its very easy to hear. You can't miss it.
Another cause for the channel imbalance could be your room. If you have something like the right speaker near a corner and the left near a free space, one speaker will have to work harder to match the volume of the other one.
Also, if you bought your speakers used, go over all the screws and make sure they are tight. They can loosen up over time.
ZD, thanks for the good elaboration on the point I raised.
Joseph54, regarding my other point, even if you have verified that the black wire from the REL is connected to a negative output terminal on the amp, I would not rule out the possibility that the cable itself is miswired. In other words the black wire could conceivably be connected to a pin on the Neutrik connector which should be connected to either the yellow or the red wire, and vice versa.
Again, the possibility that the sub's ground (which should be the black wire in the cable) is connected to a positive output terminal of the amp seems very consistent with the symptoms you have reported in all of your threads, here and elsewhere.
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https://forum.audiogon.com/discussions/follow-up-questions-regarding-my-nad-c375bee
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Pizza as we know it may have deviated a long way from its origins as a quick and easy snack sold to the poor on the streets of Naples. Purists will tell you that back in the day, there were only two types of pizza: the marinara (tomato, garlic, oregano and olive oil) and the margherita (basil, mozzarella and tomato); a far cry from the often crazy selections now on offer.
London is awash with Italian restaurants, with many claiming to serve the best pizzas this side of Naples. Some celebrate their commitment to strictly following carefully-preserved family recipes, while others have taken the simple idea of a pizza and have developed new and exciting variations.
So where can you go for the real deal in London? Here are a few suggestions for those wanting something more than the standard fare offered at the fast-food pizza chains. Presenting our best pizza restaurants in London:
It’s all about the sourdough base at this small chain of London pizzerias. The pizza takes 20 hours to make (fortunately we didn’t have to wait that long for our order), and is baked in a wood-burning brick oven which was made on-site by Neapolitan craftsmen.
The selection of toppings is modest, but there’s no denying the quality; even those who typically leave the crusts might make an exception with this tasty, soft base. Extra marks for the generous bottle of tap water placed on our table (and replenished) without having to ask.
The prices are very reasonable too – we had a pizza and a glass of wine and still got change from £10.
Another place which pays homage to Neapolitan cooking, this restaurant was set up by two brothers from Sorrento. The location, right in the heart of the action on Portobello Road, is hard to beat, and when we arrived just after 7 o’clock on a Friday evening, the restaurant was already lively.
The kitchen (and pizza oven) are open plan, and the large hams on display add to the rustic Italian vibe. Our group of 4 were impressed with the texture and flavour of our pizzas, and the shared antipasto plate gave us the opportunity to taste the hams as well as the deliciously pungent pecorino cheese. If it’s not too cold, I’d recommend getting a table by the window, allowing you to watch the action on Portobello Road as you dine.
Most pizzas are in the £9 to £12 range.
This cosy Italian restaurant looks out over Smithfield Market, and serves a fairly typical variety of pizza. The quality of the food is good, but for me the highlight of our visit was the warm welcome and overall level of service. There’s also a varied fish and steak menu – very important when someone in a group doesn’t share the others’ pizza craving.
Typical pizzas are £11-12.
It’s hardly the most likely place to come for pizza, but there’s nothing ordinary about this old warehouse building in Hackney Wick, on the banks of the Lea River. As the name suggests, the main business here is a craft brewery, and as such it’s only to be expected that it’s popular with the East London bearded hipster brigade.
Pizzas are hand rolled in the large open kitchen, and they certainly go down well with a glass of the brewery’s finest. The variety of flavours would give your Italian purist palpitations: among the standard menu are sage and truffle, lemon chicken tajine, and Middle Eastern Lamb (my favourite), while the specials board has yet more quirky offerings.
Pizzas are typically £10 to £12.
If you’re in the mood for just a slice of pizza (and when are you not?), you can do much worse than head to this trendy spot in Neal’s Yard, in the heart of Covent Garden. That’s not to say that you won’t be full after your visit – the slices are gigantic and a full pizza here is a mammoth 20 inches in diameter.
Flavours are modern twists on Italian classics, with courgette and artichoke, or salami, rocket and parmesan options on the menu. There’s craft beer and bubbly wine on draught too.
A slice is £4, while a full pizza (which could easily feed 4) is £20.
Think some place else deserves a – ahem – slice of the action? Let us know your favourite London pizza restaurants below…
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http://blog.laterooms.com/2015/12/the-best-pizzas-in-london/
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Many parents/caregivers have had experiences in the historical wherever they've had a unmannerly wakening to the information that Doctors or Physicians are only quality beings who can spawn mistakes or sometimes they merely have a bad day. We all have stories we can proportion something like hot and bad Physicians.
Fundamentally, as parents we can identify with how noteworthy it is to choose a Physician that we like, can connect to, who listens and importantly we and our offspring consciousness homy beside and belongings. Through experience umpteen of us no longest take over for any Physician merely because they deterioration the hat of a Pediatrician or GP.
In the UK we had a Family Practitioner, the benefits woman they could steal attention of my full family, so for instance, if myself and my child were ill we could both go to our Physician mutually. Additionally, they are sensible and have access to the complete family's learned profession yesteryear below one roof, which can be a super case soul and an good feature in that because of the relations ancient times relationship developed, your Physician tends to be in melody with loved ones issues which could as well impinging on you or your child's condition. That said, any satisfactory Pediatrician should hopefully be competent to team up the dots and see a relationship.Post ads:
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Here in America, the benefits of selecting a Pediatrician as anti to the Family Practitioner are that the Pediatrician has prescriptive prevalent breaking in absorption on tyke medical science. The Pediatrician's 3 period residency is dedicated to tiddler trouble and reported to The American Academy of Pediatrics we can residue assured our children are being aerated by an certified in children's aid.
Family Practitioners as well complete a iii year abidance system after learned profession seminary but their focus is on winning meticulousness of adults and pregnancies of which they may have almost 6 months Pediatric preparation. The Family Practitioner has an auxiliary commission to guarantee they resource abreast of all the latest developments or advances in Pediatric as healed as Adult medical science if they are to be an influential Practitioner.
If you elite to decide on a Family Practitioner to pleasure your brood later I would advocate you view the subsequent noteworthy points:Post ads:
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o Find a Physician who has systematic undertake treating a lot of offspring. A Physician with a duo medical specialty patients a day isn't just the thing option, it could be an demonstration that he lacks feel of treating children.
o Choose a Surgery (Physicians Office) which ever has an after hours Physician for sale that is competent to clutch strictness of brood should your Physician be unprocurable.
To find that medico who meets your criteria, you can desire referrals for a bang-up medical man from any/all the later sources:
o Family or friends, whose choices are in general supported on belongings and confidence, but tolerate in awareness that their finding is supported to be precise on how they report to the Physician, you would prominently have to scrutinize the recommendation yourself by production your own observations.
o If you've just this minute captive your previous medical practitioner can offer you suggestions, or
o Contact The American Academy of Pediatrics. It's a professional establishment which will kit out you with a catalogue of partaker Physicians in your strip. In order for the doctor to be permitted as a associate of the AAP, pediatricians must touch a clear in your mind criteria, together with beingness committee credentialed in paediatrics (which scheme a medico has realized a prescribed time of residency in the specialty, passed spoken and cursive exams and handled a minimal digit of cases). The doc essential too bequeath "evidence of dignified proper and administrative principals" as evaluated by AAP members in the quarter where on earth the Physician resides. For the names of AAP members in your community, convey SAE and a minute indicating the borough and nation state wherever you are searching, to the American Academy of Pediatrics, Department C-Pediatrician Referral, 141 Northwest Point Blvd., P.O. Box 927, Elk Grove Village, IL 60009-0927
After you ready-made your decision, should you uncover the similarity a short time ago has not formulated sanguinely between your Physician and yourself it's afterwards example to MOVE ON!
Here is a inventory of preventive signals:
o Your child's obvious psychological state active going to the Physician is on the far side what you weigh up to be a mundane fearfulness of effort a colourful.
o Your tike is ill and has prescriptive a brace various treatments but is inactive not convalescent or exploit worse. To be equal whichever treatments can be cross-grained or hard-fought to examine or victuals but a recurring disorder is a definite admonitory commemorative inscription. At this period of time ask to see a connoisseur. Its more than advantageous to have a Physician who can agree they do not cognize what the fault is fairly than make-believe to have all the answers
o The md shouldn't trade name you get the impression clueless or bothersome once you ask for more information, details, or lift a medical attentiveness for your juvenile person. You must consciousness easy to discourse your concerns on any rank near your doc.
o The medical practitioner does not put in adequate example next to your toddler and you get the impression in some way rushed during your child's scrutiny. Do you get the impression you have sufficient of an possibility to ask all your questions and get answers to what you impoverishment to know?
o The Physician over-treats your kid. Will your Physician order a full catalogue of tests for a attendant cold?
o Physician does not listen, ignores your concerns and observations. If your Physician is not fascinated in what you have to say give or take a few your child's symptoms, is disinclined to tell particulars of examinations or try-out. Maybe its time to reckon.
o Physician objects to you nonexistent a second assessment. This is a possibly dicey circumstances. Physicians are not infallible they are of course of study human beings. Secondly do not ask such as a Physician for referrals as they will more than possible cite you to being who is similar near quasi practices to themselves.
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http://sandovrll.pixnet.net/blog/post/65194520-in-your-community-convey-sae-
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This is like the Canadian version of “Smokey and the Bandit”. Well, at least the part about commandeering a truckload of beer.
A lone six pack of Moosehead beer was a key exhibit as the trial began for a New Brunswick man charged with stealing a truckload of brew en route to Mexico.
Mr. Wilson said that Mr. Haines was the person in control of the truck hauling the beer. He said that when the beer vanished, Mr. Haines himself was nowhere to be found.
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https://hailtheale.com/2005/02/09/man-steals-a-truckload-of-moosehead/
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Quantity Surveyor (Residential)
Quantity Surveyor - Residential new build apartment block - SW London
Are you looking to work for a business as ambitious as you are? Are you looking for a caree with a business that cares about your development as much as you do? I am working on a great opportunity for an experienced and Degree qualified Quantity Surveyor. The overall purpose of this role is to work alongside the Managaing Quantity Surveyor on a £170 million apartment new build project in SW London. The project consists of 190 apartments over 37 storeys, with 24 months left to completion. following on from this you will be carrying out the following tasks
- preparation of contracts, including details regarding quantities of required materials
- feasibility studies of client requests
- analysing completed work and arranging payment to contractors
- allocating upcoming work to contractors
- site visits, assessments and projections for future work
I am looking for an experienced Quantity Surveyor who will have a robust knowledge of residential new build developments from inception to completion. Successfull applicants will be Degree qualified in Quantity Surveying, and have worked on projects of similar values. You will need to be an enthusiatic and commited person who can work well in a team.
Our client is a family owned business who has become one of the largest Construction Companies in the UK. They have over 40 years experience of building homes, hotels, schools, medical centres, parks and playgrounds. Our client has also been shortlisted twice during 2017 for 'Women in Construction' awards
This is an excellent opportunity for a competent professional to join an established business who offers up to axceeding £75'000 basic salary + package Call us now for a confidential discussion on 01902 580112 and ask for Matt Lee or send your CV along with a covering letter to
Nicholas Associates Professional is a highly respected industry leading professional recruitment agency specialising exclusively in Executive Search and Selection, Construction, Engineering and Technical, and Finance and Accountancy roles across the UK and internationally. Working with many of the UK's most well-known client brands, we are passionate about matching the best talent to the best roles.
Nicholas Associates Professional is part of Nicholas Associates Group, a market leading partner of choice for talent management solutions, from Apprentice to Boardroom. For us, it's all about enabling people to be their best.
To find out more about us please visit nicholasassociates.co.uk
This job was originally posted as www.totaljobs.com/job/67971930
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https://jobs.telegraph.co.uk/job/6552547/quantity-surveyor-residential-/
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The South Fork Wildlife Area (SFWA) is a 1271-acre unit of the Sequoia National Forest along the western edge of the South Fork of the Kern River between the western boundary of the privately owned Audubon Kern River Preserve and the eastern shore of the Isabella Reservoir.
The area consists of Valley Foothill Riparian Habitat dominated by cottonwood and willow trees. It is excellent habitat for birds with over 200 species utilizing the wildlife area. Many of the birds are neotropical migrants nesting and foraging in the riparian woodlands during summer before flying to Central and South America for the winter. Birders can also find birds of prey (hawks, eagles, osprey), hummingbirds, and shore and water birds (herons, egrets, waterfowl) in and around the boundary of the wildlife area especially when the reservoir water level is high.
Recreation in the South Fork Wildlife Area is abundant and includes hiking, fishing, birding, butterfly watching, nature observation, photography, canoeing, and kayaking.
In 2014, Sequoia National Forest crews cleared a one-mile loop trail accessed from the Sierra Way trail head, 2 miles west of Hwy 178.
In high water years, it is possible to kayak through the forest while quietly observing the wildlife or fishing (please remove any snagged mono-filament so wildlife is not harmed). In summer, wildlife trails can be an adventure to follow. Watch for ticks and check yourself after visiting the area. Both dog and deer ticks are found in this area. In normal years the South Fork of the Kern River will flow through the center of the wildlife area so plan on stopping at the water's edge or getting wet. The river is highest when the mountain snows are melting April through early June. In summer it normally braids to a meandering stream until upstream water diversions stop the flow entirely by late July. The dry river is normally replenished in late November depending on rain and snow fall.
Wildlife viewing opportunities are best at dawn and dusk. Birds of grassland, open water, riparian, and shoreline habitats can be found. Species to look for include wintering populations of Bald Eagle and other raptors; year round populations of Western Grebe, Clark’s Grebe, American White Pelican, Osprey, Red-shoulder Hawk and Western Bluebird; and spring to summer populations of Tree Swallow, Yellow Warbler, Common Yellowthroat, Summer Tanager, Blue Grosbeak, Lazuli Bunting, Tricolored Blackbird, and Lawrence’s Goldfinch can be found. Mammals include mule deer, beaver, coyotes, gray fox, bobcat, striped skunk, wood rats, desert cottontail and raccoons.
Accessible year round. The area is subject to flooding during years of high run-off. Flooding completely inundates it every 7 years or so, at which time it can be accessed by boat.
Directions: Parking lots for South Fork Wildlife Area are on the south and north side of the wildlife area. Access to the southern parking is directly off of Highway 178 just east of South Lake and 1 mile west of Sierra Way. Drive down a dirt road (Patterson Lane) about 1/4 mile, the entrance to the wildlife area is on your right. Park and walk in.
To access the northern parking area, drive 11 miles east of town of Lake Isabella on Highway 178 to Sierra Way. Turn north on Sierra Way. The parking lot is directly off of Sierra Way, 3/4 of a mile north of the Sierra Way bridge over the South Fork of the Kern River. This part of the wildlife area is may be flooded from November to June. (The land around the Sierra Way bridge is privately owned by the National Audubon Society and not part of the publicly owned wildlife area.)
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https://www.sierranevadageotourism.org/content/south-fork-wildlife-area-sequoia-national-forest/siefd98022fffa598e4d
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If there was any doubt Arnold Schwarzenegger shtuped his former maid …. DOUBT NO MORE … “cause his love child is about to turn 16 — and he looks just like his humungous father.
Standing roughly 8″2″ and weighing an estimated 475 lbs (pure muscle) … genetic jackpot winner Joseph Baena strolled alongside his mother Mildred during a shopping excursion in Bakersfield, CA yesterday.
Joseph was sporting a shirt from a swimming and diving competition — it”s unclear if he participated, but we”re guessing if he did, he dominated … based purely on his enormous physique.
Fun Fact — Arnold first began competitive bodybuilding around the age of 16 … and eventually excelled in competitive adultery.
Happy birthday Joe!
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http://copcop.net/arnold-schwarzeneggers-love-child-im-huuuuuuuge/
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14872799
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Microsoft Extends XP Deadline for Low-Cost MachinesJune 3, 2008 – 10:33 AM
Microsoft has further extended the life of Windows XP so that computer makers can include the operating system on low-cost desktop PCs, the company announced at the Computex trade show on Tuesday.
Microsoft has been under pressure from computer makers to provide a version of its OS for an emerging class of very low-cost laptops and desktops. Its new Windows Vista OS is widely seen as too resource-hungry for those machines.
In April Microsoft extended its deadline for selling Windows XP licenses for low-cost laptops like the Asus Eee PC. It had originally planned to stop selling most XP licenses on June 30.
At Computex on Tuesday it said it has now also extended the deadline for low-cost desktops. PC makers can now include Windows XP in those systems until 2010, the same as the deadline for low-cost laptops, said Rob Young, a senior director with Microsoft’s OEM group.
In a statement, Microsoft said the extension applies to “nettops,” a term coined by Intel to refer to low-cost desktops that have limited system configurations and are intended for simple tasks like surfing the Internet and sending email. Examples include the upcoming Asus Eee Box, which is on show here at Computex.
It was unclear what limitations Microsoft may put on PC makers to prevent them from installing Windows XP on more capable machines. Young said Microsoft and PC vendors are in general agreement over what constitutes a nettop and suggested that Microsoft won’t specify the hardware configurations that vendors can use with XP.
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https://www.pcsympathy.com/2008/06/03/microsoft-extends-xp-deadline-for-low-cost-machines/
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