sha256
stringlengths
64
64
language
stringclasses
27 values
size
int32
1
491k
lines
int32
1
21.8k
content
stringlengths
1
200k
a1d18daa58c674437951616ca18e894a94fd3538fba19966cad5bfef4125076b
Text
4,912
66
[![Documentation Status](https://readthedocs.org/projects/hippunfold/badge/?version=latest)](https://hippunfold.readthedocs.io/en/latest/?badge=latest) ![Docker Pulls](https://img.shields.io/docker/pulls/khanlab/hippunfold) ![Version](https://img.shields.io/github/v/tag/khanlab/hippunfold?label=version) <img align="rig...
a5d1a936a827571eef234620592dbb2aa9f5650e78b436265931ddc94e7c84d6
Text
4,946
157
# ROIpy ## Description **ROIpy** is a python package for ROI (Region of Interest) semi-automatic generation and placement for functional imaging of neuronal dendrites of individual neurons. It provides a tool for defining, managing and visualizing dendritic ROIs. In addition, provides a benchmark for analyzing morpho...
457a0ee08d2b64892bfb7a7b4d839381b80779b99b93a9759f09210180e19b1c
Text
4,948
110
DATASET: HIF-1α and HIF-2α Are Upregulated in the Hippocampus but Not in the Medial Prefrontal Cortex in Experimental PTSD ================================================================================ AUTHORS ================================================================================ Denys Porkhalo (1), ...
3db2d946482d46e377831e90edb3ef5496febaa621edc08c25ce58d99a015c5c
Text
4,963
143
HYDRA Section of Biomedical Image Analysis Department of Radiology University of Pennsylvania Richard Building 3700 Hamilton Walk, 7th Floor Philadelphia, PA 19104 Web: https://www.med.upenn.edu/sbia/ Email: sbia-software at uphs.upenn.edu Copyright (c) 2018 University of Pennsylvania. All rights...
f8b1f051651b4b09314505cbe2fb36b08d7fb7610c6a5c6e92c9f0d8097004c1
Text
5,037
159
# ROIpy [![DOI](https://zenodo.org/badge/780942663.svg)](https://doi.org/10.5281/zenodo.21334248) ## Description **ROIpy** is a python package for ROI (Region of Interest) semi-automatic generation and placement for functional imaging of neuronal dendrites of individual neurons. It provides a tool for defining, mana...
5f892c8872a854c9029ac77fce0c6523512d10a9e1b064122112bc2a5c7c5475
Text
5,062
109
# Snakebids [![Tests](https://github.com/khanlab/snakebids/actions/workflows/test.yml/badge.svg?branch=main)](https://github.com/khanlab/snakebids/actions/workflows/test.yml?query=branch%3Amain) [![codecov](https://codecov.io/gh/khanlab/snakebids/graph/badge.svg?token=Q15K5HX7W9)](https://codecov.io/gh/khanlab/snakebi...
9117f9d255d6b6e810d224a600d381192bccccd3f0cd417fed9559d49ca8fffd
Text
5,065
83
# Pangolin Pangolin is a deep-learning based method for predicting splice site strengths (for details, see [Zeng and Li, Genome Biology 2022](https://doi.org/10.1186/s13059-022-02664-4)). It is available as a command-line tool that can be run on a VCF or CSV file containing variants of interest; Pangolin will predict ...
9796b0d9b81dfe27a214021811289d8e5587a572d7ba0c3b7f3f453a83f5bceb
Text
5,122
68
# Numerical optimization of gradient waveforms (NOW) for tensor-valued dMRI A MATLAB package for optimization of gradient waveforms that yield b-tensors of arbitrary shape that can be tailored to pulse sequence timing and hardware restrictions. The optimizer supports the following: * Arbitrary b-tensor shape * Varia...
c047127cebef46379bdf65c765e3b5a515b520466033011f0ba2a87207b87ae9
Text
5,223
137
# Dynamic Functional Connectivity Toolbox (`dFC_toolbox_app`) This repository includes portions of the following freely available software: - Brain Connectivity Toolbox available at https://www.nitrc.org/projects/bct/ - Tools for NIfTI and ANALYZE image available at https://www.mathworks.com/matlabcentral/fileexch...
552bda787b4b79ec60b3671f04c67659c6242a1119a5c148436c86f43e239ea7
Text
5,284
98
# allen_conn_maker — shareable bundle This folder contains a two-stage pipeline that builds a single-cell synaptic connectivity matrix for the mouse brain by combining: - per-neuron MERFISH coordinates from the Zhuang Allen Brain Cell Atlas (ABCA), and - the Allen Institute mesoscale voxel connectivity model (Knox et...
6ce87c2dab378518bd081d99d038be3460de732cd67f3ea0bf54a135ba066d85
Text
5,352
120
# "Stabilized hierarchical deep neural networks with multiple knockoffs (Stabilized HiDe-MK)" ## Overview Deep neural networks (DNN) have been used successfully in many scientific problems for their high prediction accuracy, but their application to genetic studies remains challenging due to their poor interpretabil...
a861ccefa033ab477947e115ece467c52a8931213275edfd27823c308cf7ac25
Text
5,434
153
# adpbulk # Summary Performs pseudobulking of an `AnnData` object based on columns available in the `.obs` dataframe. This was originally intended to be used to pseudo-bulk single-cell RNA-seq data to higher order combinations of the data as to use existing RNA-seq differential expression tools such as `edgeR` and `DE...
dacf861714b8c4547bf4dd83a41d898ade80d7b5247c366fcd492baaffa7394f
Text
5,525
155
# adpbulk [![DOI](https://zenodo.org/badge/437088194.svg)](https://doi.org/10.5281/zenodo.20736457) # Summary Performs pseudobulking of an `AnnData` object based on columns available in the `.obs` dataframe. This was originally intended to be used to pseudo-bulk single-cell RNA-seq data to higher order combinations o...
a287ca9c9c199c898ba2fa3b7a4b5d00cef82b10dd9630c59c77e9b8fca6f4a6
Text
5,533
82
# DeepLINK: Deep Learning INference using Knockoffs DeepLINK is a variable selection algorithm that guarantees the false discovery rate (FDR) control in high-dimensional settings. It consists of two major parts: an autoencoder network for the knockoff variable construction and a multilayer perceptron network for featu...
ba542916d9bb584807649c1c8f3974e7098c8d245fdac8d36d4d1011cd734da2
Text
5,537
124
# CELER: A 365-Participant Corpus of Eye Movements in L1 and L2 English Reading Eye movement recordings of 69 native English speakers and 296 English learners reading Wall Street Journal (WSJ) newswire sentences. Each participant reads 156 sentences: 78 sentences shared across participants and 78 unique to each partic...
a0982c590937157412d00a884667544b7589bc6dff667cea7a511efc3bbd2eee
Text
5,561
116
# EB-Segmentation-Mask2Former Code to train and evaluate the Mask2Former architecture for Epidermolysis Bullosa (EB) wound image segmentation, developed for the paper **'AI-based segmentation of wound types caused by Epidermolysis Bullosa'**. *Note: A link to the paper will be provided here following its a...
ba97b14dde36322c24f729c3b64734076d6779bf47b9ee6aa066fa3695f6024b
Text
5,593
117
# Hierarchical Spiking Neural Network This project models the primate ventral visual system (PVVS) as a hierarchical spiking neural network (HSNN) trained via spike-timing-dependent plasticity (STDP). This is to study the emergence of feature selectivity of shapes and to evaluate a hypothesis for feature binding - hie...
f53daa5fdd1ee6ca5ec4c3b75eafe83b9c858a5698cc02e8cf9441fcb6a4cf7e
Text
5,698
122
# Update Jan 16, 2026 ### A more recent implementation of LD score regression in python 3 can be found at https://github.com/CBIIT/ldsc. See also the accompanying [web browser](https://ldlink.nih.gov/ldscore) and [preprint](https://doi.org/10.64898/2025.12.19.695639). # LDSC (LD SCore) `v1.0.1` `ldsc` is a command l...
8c8100e208b15a89ee8b93cb87b6d575a73a266a2924906a8307cc84fe650784
Text
5,712
146
———————————— GENERAL INFORMATION ———————————— This readme file was generated on [2026-05-26] by [Emily Meeus] This repository contains the R scripts and source data tables used to generate the expression, morphology, and developmental phenotype analyses reported in the paper “ATP13A4 gates extracellular polyamine l...
e9884266d5ff2075876b4cb91ad334a06e049cadb88fdbb49720da33fb9fa2da
Text
5,720
97
<img src="yanat.png" alt="drawing" width="400"/> At the moment, this bad boy containts a few network communication metrics and models at its `core` and a game-theoretical network generation framework at `generative_game_theoric`. I'll just add more stuff as I go. ## Installation Guess what, `pip install yanat` is all...
7a351ac16738da2ef0ccd22c731b18d6c94d78a161db58124eef73f69576756b
Text
5,769
175
# *Stoic* Fast and accurate protein stoichiometry prediction. [![license](https://img.shields.io/badge/license-MIT-blue)](https://github.com/PickyBinders/stoic/blob/master/LICENSE.txt) [![bioRxiv](https://img.shields.io/badge/bioRxiv-2026.03.13.711535-blue.svg)](https://www.biorxiv.org/content/10.64898/2026.03.13.71...
1d7f910968a7fc8c2707b9236a67923b7068de2a604647c60c013eadd4bd993b
Text
5,833
132
# SlotDeconv <p align="center"> <img src="framework.png" alt="SlotDeconv workflow overview" width="900"> </p> SlotDeconv is a reference-based spatial transcriptomics deconvolution method for estimating spot-level cell-type proportions from spot-based spatial transcriptomics data. It learns discriminative cell-type...
7f145b15811926cf78d67d1a4fb169f7384812b74e6f61fefecfc0a0b7d8f83b
Text
5,957
195
# **DiffusionOT** ![Doc/overview.jpg](https://github.com/liujuntan/DiffusionOT/blob/main/Doc/overview.jpg) **DiffusionOT** is a dynamic **Regularized Unbalanced Optimal Transport (RUOT)** model that reconstructs cellular trajectories and landscape from time-series scRNA-seq snapshots as well as a **Stochasti...
3a3a5d37264180878784fed928dc645aa1d335e389985e73b53db474b4cd070c
Text
6,095
183
# **DiffusionOT** ![Doc/Overview.jpg](https://github.com/liujuntan/DiffusionOT/blob/main/Doc/Overview.jpg) **DiffusionOT** is a dynamic **Regularized Unbalanced Optimal Transport (RUOT)** model that reconstructs cellular trajectories and landscape from time-series scRNA-seq snapshots. Additionally, a **Stochastic ...
df7326673650d6f3c502311634de6ab20b94867b8941698d54c22151f7784917
Text
6,182
110
# mcw_Preclinical_MRIsequences Public-facing repository for various MRI pulse sequences developed by M Budde at the Medical College of Wisconsin. This repository is replacement for the previous [OSF sharing site](https://osf.io/ngu4a/) :bangbang: **To access sequences (private repositories), follow these [instruction...
1edbaf669cf27dd23651022d85d352edc368412d7003a14b8dd3a9d023a3cb24
Text
6,289
140
# Brain STRIDE: Longitudinal Harmonization and Atrophy Analysis R Markdown pipeline for harmonizing longitudinal brain volumetric measures across imaging protocols and analyzing individual atrophy trajectories in relation to lifestyle factors. ## Overview This repository contains three analysis scripts that are inte...
e99e1501c44612f49fb3d5df36b65d00b11a943f8efc7a00b7df0b41e4284442
Text
6,294
53
### :tada: Update (Aug 2021): Interested to see how well your model copes with challenging stylized images? Check out the comprehensive toolbox at [bethgelab:model-vs-human](https://github.com/bethgelab/model-vs-human), which supports stylized data (complete with human comparison data) and comes with code to evaluate a...
d590ee7781b9c180d7aa0c4e29737723bc7ea8ed8fb2ee7936ce52f3c9eab7de
Text
6,310
134
# A data-driven evaluation of optimization techniques in cell culture media Code and input data for the *Bioinformatics* paper **"A data-driven evaluation of optimization techniques in cell culture media."** It benchmarks Bayesian optimization, design-of-experiments, and baseline search strategies on six published cel...
58eecd3ec8cf8489563a99c0f04ecc5ec237637460e0bcf4203b34bf0cb3d79e
Text
6,409
164
# HIF and PACAP gene expression in SPS-induced rat PTSD model Statistical analysis of HIF-1α, HIF-2α, HIF-3α, PACAP and PAI-1 gene expression in hippocampus and medial prefrontal cortex of rats with an SPS-induced PTSD model. Includes normality testing, two-group comparison (t-test / Mann-Whitney U), and publication-r...
478bbcbcfef0f19365da174b5ef82481109bdf437ba7e2d26b818d21c53e7306
Text
6,470
173
# MiniMORPH: A Morphometry Pipeline for Low-Field MRI in Infants ## Overview This script is designed to run the ANTs pipeline for segmenting infant brain images on Flywheel. The pipeline consists of the following steps: 1. Register segmentation priors (tissue and CSF) and segmentation masks (ventricles, subcortical G...
2ae911bd488b212e030492ebcbdbbc70ba4cb7d2538535765c691f248bc194ce
Text
6,506
141
# iEHM Image analysis code used in the iEHM (innervated Engineered Human Myocardium) publication, "Innervated human cardiac muscle model reveals sympathetic drivers of KCNH2-associated arrhythmias" (accepted, *Nature Communications*). The pipeline segments vasculature and axons (neurofilament) in confocal microscopy s...
67599558bcc70ea7061cf7573a26e1f77e6a05a2b457d73ea58fae131a80a246
Text
6,519
178
# nfml Machine learning for the computational discovery of **ferroelectric nematic (N<sub>F</sub>)** liquid crystals. The package does two things. It **predicts N<sub>F</sub> properties** — whether a molecule exhibits the N<sub>F</sub> phase (classification) and at what temperature it transitions (regression) — using...
177795145138902f960e8ea4fa9c8bc1807511855256dae9b8493d701ed10434
Text
6,566
144
# Garnet force field [![Build status](https://github.com/greener-group/garnet/actions/workflows/CI.yml/badge.svg)](https://github.com/greener-group/garnet/actions/workflows/CI.yml) [![License](https://img.shields.io/badge/license-MIT-green.svg)](https://github.com/greener-group/garnet/blob/main/LICENSE.md) If you use...
827f4304258fd84aa83e202a39a80fc73c333eb66b5e546ee9e1e8fb4bc465ff
Text
6,701
108
# Glia_3740732_Data Repository of series of data sets used in the publications of the paper "Dorso-Ventral and Night-Day Regulation of Extracellular K+ Dynamics in Mouse Hippocampal Astrocytes" in Glia # Electrophysiological and Structural Dynamics of Astrocytic Currents across Circadian Rhythms (ZT) and Brain Regions...
73af3bedfc34fed1b03b584e9a5721cf7b5baa0e50020c5ee10fc630152dc230
Text
6,778
108
# Glia_3740732_Data Repository of series of data sets used in the publications of the paper "Dorso-Ventral and Night-Day Regulation of Extracellular K+ Dynamics in Mouse Hippocampal Astrocytes" in Glia # Electrophysiological and Structural Dynamics of Astrocytic Currents across Circadian Rhythms (ZT) and Brain Regions...
da9d333594cae6065b8ea67ecff8b8a0a8836be6405915996f74fb9a8dc92ae8
Text
6,839
93
# Fgfr1_analysis To be written sessionInfo() R version 4.3.3 (2024-02-29 ucrt) Platform: x86_64-w64-mingw32/x64 (64-bit) Running under: Windows 10 x64 (build 19045) Matrix products: default locale: [1] LC_COLLATE=English_Sweden.utf8 LC_CTYPE=English_Sweden.utf8 LC_MONETARY=English_Sweden.utf8 [4] LC...
dbf11762504513fd57167ce3c12c04c72f9baf567496b88d05837c564b689722
Text
7,148
140
# Vox2Cortex and related methods *Note*: This repository has been refactored entirely, you can find the old Vox2Cortex repo [here](https://github.com/ai-med/Vox2Cortex/releases/tag/v0.1.0). *Note*: For an implementation of V2C-Long, see [this](https://github.com/ai-med/V2C-Long) repo. This repository implements sev...
902392247ae7b6ce859a3b331071a2360bbed773a381ea2ddcc89794632ff76d
Text
7,260
157
# Frost & Microstructure Classification [![OSF Project](https://img.shields.io/badge/OSF-TYDSM-0B3D91?logo=osf&logoColor=white)](https://doi.org/10.17605/OSF.IO/TYDSM) [![License: CC0-1.0](https://img.shields.io/badge/License-CC0_1.0-lightgrey.svg)](https://github.com/SofiaKouki/frost_action_classification#CC0-1.0-1-o...
629d9e571828c113518ebebe31551e29cc7652353bb64c26059352a67feb1e97
Text
7,400
66
<picture> <source media="(prefers-color-scheme: dark)" srcset="docs/source/_static/images/logo/chemprop_logo_dark_mode.svg"> <img alt="Chemprop Logo" src="docs/source/_static/images/logo/chemprop_logo.svg"> </picture> # Chemprop [![PyPI - Python Version](https://img.shields.io/pypi/pyversions/chemprop)](https://b...
d5316af44ab77f36efcc1f7b6466598fd4d726ef4757e55e54ba2f21431bee75
Text
7,436
193
# File descriptions ### AlphaMissense_hg19.tsv.gz, AlphaMissense_hg38.tsv.gz Predictions for all possible single nucleotide missense variants (71M) from 19k human protein-coding genes (canonical transcripts) for both hg19 and hg38 coordinates. These files are sorted by genomic coordinates. ### AlphaM...
72203c8f27dc0c97e629bf5beec67799854bdcb4380023b598ff61ca04e60aab
Text
7,470
135
# neuronephys — mouse cortex simulation engine (minimal share package) GPU-accelerated large-scale simulation of the mouse isocortex: ~300K Hodgkin–Huxley neurons with realistic Allen Brain Atlas (Zhuang MERFISH) connectivity. CUDA C++ with Thrust, targeting NVIDIA GPUs. This folder is a **minimal, self-contained cop...
c7e733f33c2b2dce6735e620179e8f95fc82f42bd367bc8b7d9489938f6e2172
Text
7,523
202
# Postpartum Brain Age Prediction **Conceptual implementation of the postpartum brain age prediction model** This repository provides a PyTorch implementation of the deep neural network used to predict brain age from structural MRI in postpartum and nulliparous control women. The model: - Uses three CAT12-derived ti...
10e6054aab9ad8fdd86bc605f2b72d01503cd8d1ada4fd9aa39b031b9efc81e2
Text
7,528
142
<p align="center"><em>Mesa 4 is in active development! Checkout our latest <a href="https://github.com/mesa/mesa/releases">pre-releases</a> and <a href="https://github.com/mesa/mesa/issues/3132">issue tracker</a>. <br>For GSoC, checkout our <a href="https://github.com/projectmesa/mesa/wiki/Google-Summer-of-Code-2026">G...
80bd67831926ef6fb20ccd199787cd7b67b124a2b391e9b984642ee60d91fe4a
Text
7,657
52
Shield: [![CC BY-NC-SA 4.0][cc-by-nc-sa-shield]][cc-by-nc-sa] This work is licensed under a [Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License][cc-by-nc-sa]. [![CC BY-NC-SA 4.0][cc-by-nc-sa-image]][cc-by-nc-sa] [cc-by-nc-sa]: http://creativecommons.org/licenses/by-nc-sa/4.0/ [cc-by-nc-s...
345f4b00e26107c5a217cb6fedef264e4993cda047b67040d622aed7efcab5de
Text
7,698
350
# Early Detection of SARS-CoV-2 Variant Dominance and Hospitalization Impact This repository contains the analysis pipeline used in the study: **“From Sequences to Strategies: Early Detection of New SARS-CoV-2 Variants via Genetic Distance to Reduce Hospitalizations.”** The project integrates genomic surveillance, m...
ca5a86e105bfdd6f277b484a71591267a41f362c401abb1cea4152a8f1b57ae0
Text
7,754
123
[![Docs](https://github.com/navis-org/navis/actions/workflows/build-docs.yml/badge.svg)](https://github.com/navis-org/navis/actions/workflows/build-docs.yml) [![Tests](https://github.com/navis-org/navis/actions/workflows/test-package.yml/badge.svg)](https://github.com/navis-org/navis/actions/workflows/test-package.yml)...
d09e98f442ee039564880b86b2dab723cd8e86626d6f7d398f44d8880451c3f3
Text
7,862
155
RingFinder ========== Automated image analysis for finding the fraction of structure presenting a given pattern. Originally developed to identify the 190 nm periodicity in the actin/spectrin cytoskeleton of neurons. Installation ~~~~~~~~~~~~ Ubuntu ^^^^^^ Run in terminal: :: $ sudo apt-get install python...
ba8f9cd01b3630936c5525f29bec2ce7377f3358e4104dbbb32af3e3fba46c49
Text
7,874
134
# WORC: Workflow for Optimal Radiomics Classification (v3.7.1) <a href="https://bigr.nl/"><img src="https://bigr.nl/img/bigr.jpg" alt="Your Image Alt Text" width="200"/></a> ## Information | Unit test | Documentation | PyPi |Citing WORC | |-...
192d9a630a0d929019e4dc369bebd897b8f38aeb4049b661c4ba2f4763fb9d12
Text
7,908
201
# SpatialModal ![SpatialModal Overview](./SpatialModal_Overview.png) ## Overview SpatialModal is a multimodal graph learning framework for spatial transcriptomics analysis. It integrates gene expression, spatial coordinates, and optional histological image features to learn spatially aware latent representations for...
39cb28cd9ebb023d922427ebf5805c102eee450f72ffbf20c46599f2f8bc6f7c
Text
7,987
166
<img width="100%" height="300px" alt="NoClaMe_GitHub" src="https://github.com/KylleV/noclame/blob/main/NoClaMe_GitHub.svg" /> # Node Classification Metrics, (NoClaMe) A small script containing four different metrics for binary node/vertex classification: top-k and three new metrics **NRD**, **ANPI** and **RRCS**. ...
2932d9a528fc4c5ca928cf8f87088d2a2bb8a1b679122ed02bcbf782588869dc
Text
8,040
144
WORC: Workflow for Optimal Radiomics Classification (v3.7.1) ============================================================ Information ----------- +-------------------+------------------+------------------+-------------+ | Unit test | Documentation | PyPi | Citing WORC | +===================+===...
d4705ee4678e07f77dbb85342ed14ca8b7b2ad317b23afb97c722870532f529a
Text
8,108
178
# Visual Prompt Engineering for Multimodal and Irregularly Sampled Medical Data Malte Tölle, Mohamad Scharaf, Samantha Fischer, Christoph Reich, Silav Zeid, Christoph Dieterich, Benjamin Meder, Norbert Frey, Philipp Wild, Sandy Engelhardt Paper link: https://arxiv.org/abs/2501.18237 ## Abstract A multitude of exami...
9930615e5307c6cc027102e8f479ebe7ba48132ef7641ffd482a52134aeb82d2
Text
8,146
193
# Alzheimer's Disease Biomarker Visualization Tools <!-- badges: start --> <!-- badges: end --> <p align="center"> <img src="raindrop_animation_demo.gif" alt="Longitudinal biomarker trajectories" width="450"> </p> > Interactive Shiny applications for visualizing longitudinal Alzheimer's disease biomarker trajector...
39be8950b2745908c700e7c5c247071520d15eebabacbf4823b9a6b9b6be605d
Text
8,156
187
# Biostatistics WD - Postural Asymmetry and SF Analysis A comprehensive R-based biostatistics project for analyzing postural asymmetry (PA) measurements in rats, with a focus on withdrawal (WD) studies using Bayesian statistical frameworks. ## Project Overview This project provides tools and analyses for studying po...
03db4c0b1fd91b01a7ba7d135cc655204972053b8dff48e17757622c24b3c40a
Text
8,408
93
# PyBrainAge ## PyBrainAge development Here we introduce PyBrainAge (beta version) which is a Brain-age model designed to estimate age (brain-age) based on structural T1-weighted MRI brain scans. Below, you will find additional information about the model and instructions on running it with your preprocessed T1-weight...
e8ed60134fb9cf9ece9c87bba9c4a296f18907372a0e9e21f62206e0702b2cfd
Text
8,448
170
[![Python version](https://img.shields.io/badge/python-3.8-blue)](https://www.python.org/downloads/) [![License](https://img.shields.io/badge/licence-GPLv2-blue)](https://www.gnu.org/licenses/old-licenses/gpl-2.0) [![GitHub release (latest by date)](https://img.shields.io/github/v/release/algbio/spl-IsoQuant)](https://...
849482de545771e3a41cd0a3dc52e1bbd447d1e1d6687a6e790c96dc47520eba
Text
8,500
143
## Repository information This repository contains the code and data resources used to reproduce the behavioral, EEG, computational modeling, and figure-generation analyses reported in the manuscript “Impaired midfrontal-motor theta phase synchronization characterizes maladaptive motivational behavior in obsessive-com...
976e339e35ccb21961d0096a6b1610881ae36fe673078ab30105ced304b413e4
Text
8,612
181
[![PyPI](https://img.shields.io/pypi/v/scMethyAnno.svg)](https://pypi.org/project/scMethyAnno) # **MethyAnno: An Interpretable Automated Annotation Method Leveraging Multi-scale Information and Metric Learning Framework for scDNAm Data** ![MethyAnno](./MethyAnno.png) ## Introduction **MethyAnno** is an interpretable...
8f20353d3200285e2cdb54475d4ab2875432cb82f3b9def6351c0e769452d2c4
Text
8,664
157
![Molly logo](https://raw.githubusercontent.com/JuliaMolSim/Molly.jl/master/docs/src/images/logo_molly.svg) [![Build status](https://github.com/JuliaMolSim/Molly.jl/workflows/CI/badge.svg)](https://github.com/JuliaMolSim/Molly.jl/actions) [![Coverage status](https://codecov.io/gh/JuliaMolSim/Molly.jl/branch/master/gra...
6318ec10431cd2113bad29ba65d0ef82f6a1b8c54b4d3dde184f2791dd12c4b0
Text
8,721
239
# pHoptNN Predict enzyme **pH optima** directly from 3D protein structures using an **Equivariant Graph Neural Network (EGNN)**. Includes dataset generation, training, prediction with attention export, and visualization & analysis tools. --- ## Features - **EGNN model** with attention and edge features (`egnn.py`...
5b982f8be69e67815ca87aa869f58011a521f0253235174aa13f5782b7eb8650
Text
8,903
128
# PISA 2022 Science Association and Model-Attribution Analysis This repository contains the analysis code supporting the revised manuscript, *Recurrent and system-specific model-attribution patterns in PISA 2022 science performance across nine education systems*. ## Scope The repository provides the workflow for bui...
6db25e56fb100bdea58762948c2a04402b1a23aaed083844603efd336d5ec56c
Text
9,371
252
<img width="100%" alt="STABL" src="./front_page.png"> # Discovery of sparse, reliable omic biomarkers with Stabl [![DOI](https://img.shields.io/badge/DOI-doi:10.1038/s41587--023--02033--x-blue.svg)](https://doi.org/10.1038/s41587-023-02033-x) [![Python version](https://img.shields.io/badge/Python-3.7%E2%80%933.12-blue...
d0bfabf393abcd480794b62b8f99d086d962cda25fb8250269a63c8dbcc61513
Text
9,596
116
# Data and code for: *Prioritizing removals of a highly cryptic invasive species using machine learning and demographic weighting* This repository is the research compendium (data and novel statistical code) for: > Romer, A. S., et al. 2026. Prioritizing removals of a highly cryptic invasive species using machine lea...
f21589f5a30cb0d2670f55a727ee53326d6b049b60b102060e1945a9f129dc6e
Text
9,750
189
# CW-Net Reproducibility Capsule — Autonomous Driving This repository contains all code, data, and materials to reproduce the results from the CW-Net paper on concept-based explanations for autonomous driving. ![Overview of the CW-Net architecture and autonomous-driving evaluation pipeline.](images/cwnet.png) *Figur...
8d2d6aeff1d2e4001018b57424a12554d958dcf45335ab09bc5246312a91995a
Text
9,838
152
# Decomposing condition-related signals, effect modifiers, and batch effect of complex forms in scRNA-seq studies with neural discrete representation learning by: Xiao Xiao (xiao.xiao.xx244@yale.edu) ![](./Figure1_overview.png) --- ![](./Figure2_DL.png) ## Abstract Advances in single-cell sequ...
395dd380215ca928940c39bbf4808283cf9e06baa85b0fd075abd081a4a18903
Text
9,909
153
# brainageR Software for generating a brain-predicted age value from a raw T1-weighted MRI scan. This uses a Gaussian Processes regression, implemented in R, using the kernlab package. The software takes raw T1-weighted MRI scans, then uses **SPM12** for segmentation and normalisation. A slightly customised version **...
8788f5562779478188758e6b671aa22095d95b6c44154332446790045a79c9e2
Text
9,978
235
![MICAFlow logo](https://raw.githubusercontent.com/MICA-MNI/micaflow/main/docs/source/_static/images/logo.png) # MICAFlow: Accessible, fast, and pythonic MRI processing pipeline <div align="left"> [![Version](https://img.shields.io/github/v/tag/MICA-MNI/micaflow)](https://github.com/MICA-MNI/micaflow) [![PyPI v...
7d4c741dd55f4667997f10c70b7356d45a4703e514f2cfa33efebec858519421
Text
10,273
187
## Perceptual Similarity Metric and Dataset [[Project Page]](http://richzhang.github.io/PerceptualSimilarity/) **The Unreasonable Effectiveness of Deep Features as a Perceptual Metric** [Richard Zhang](https://richzhang.github.io/), [Phillip Isola](http://web.mit.edu/phillipi/), [Alexei A. Efros](http://www.eecs.be...
8c0972cab4c4d32230cdca7242d141b88b97bda3a0b3e1271c6f4261702ab948
Text
10,318
190
# RINAMI: Residue-attributed Interpretable Neural network for predicting Absolute folding free energy by Merging structure and sequence Information !["Figure of architecture"](./Figure/Figure1_RINAMI.png) ## Tested environment: ``` - NVIDIA Driver: 530.41.03 - CUDA: 12.1 - GPU: NVIDIA GeForce RTX 3080 (10GB) ``` #...
adce9ef65be00334b2cb992ead71a7150b984865784364b8526d8317217d1ac0
Text
10,818
318
# mmVelo Tutorials This directory contains tutorials for **mmVelo**, a deep generative model designed to estimate cell state-dependent dynamics across multiple modalities. By utilizing splicing kinetics and multimodal representation learning, mmVelo infers cell state dynamics on joint representations and estimates tem...
79dbb69ae161cc0087fe63741ffdaf6c5eb247a452f7dd06076f2a38cc33376d
Text
11,012
123
> [!Warning] > **Project deprecated** > > LSL-actiCHamp is no longer maintained and has been deprecated. > Please find the new BrainVision LSL Connector for actiCHamp and corresponding documentation directly on the [Brain Products website](https://www.brainproducts.com/downloads/more-software/#lsl) as free downloads. ...
c941f18b44957fe1fbb713af3c3ce51884da7c6227cdb34bf21bbbdf851c36b1
Text
11,293
171
# IJ BAR [![DOI](https://zenodo.org/badge/8709403.svg)](https://zenodo.org/badge/latestdoi/8709403) [![Latest Release](https://img.shields.io/github/release/tferr/Scripts.svg?style=flat-square)](https://github.com/tferr/Scripts/releases) [![Issues](https://img.shields.io/github/issues/tferr/Scripts.svg?style=flat-squa...
1c963429a0e2cdc8741aadd61103187dd33bb925089087278d85d2a52ae732ee
Text
11,351
294
# neuroHarmonize Harmonization tools for multi-site neuroimaging analysis. Part of the work reported in our paper with data from the ISTAGING consoritum [^1]. > **⚠️ IMPORTANT - Version 2.5.1 NIFTI Precision Fix** > If you have previously harmonized NIFTI images using `applyModelNIFTIs` with versions < 2.5.1, **you...
3e2e8b5cbd0993aa99076af66ea4591deff68be57a7d8a91b40ed455327c66e8
Text
11,664
230
# REACT: Receptor-Enriched Analysis of functional Connectivity by Targets [![DOI](https://zenodo.org/badge/362894234.svg)](https://zenodo.org/badge/latestdoi/362894234) ![Graphical abstract](https://user-images.githubusercontent.com/79755700/116727558-a0c38700-a9dc-11eb-8ecc-28b3446b9d11.jpg) The `react-fmri` softwa...
e2588e2d6d8975758ecef8f6e4c6926bbbf3ebe1281f0366d6c4072d8ede289c
Text
11,752
299
# MorphoScope A Python-based GUI application for quantifying structural plasticity in neuronal projections, implementing the methodology from Petsakou et al., 2015 (*Cell*). ## Overview This tool provides automated 3D quantification of neuronal structural plasticity from confocal microscopy images. It calculates: - ...
d0cc90d952cb0bcc543e8016574bff243d44d6e4363a19aeb95dd5e4f46e5ae5
Text
11,911
223
# Proseq2.0 Preprocesses and Aligns Run-On Sequencing (PRO/GRO/ChRO-seq) data from Single-Read or Paired-End Illumina Sequencing. It is a new version of ProseqMapper (https://github.com/Danko-Lab/utils/tree/master/proseq). Currently we provide two commands: proseq mapper and bigWig merge. ## Overview Our proseq2.0 pi...
8c30bfcbf596349c281e138265bb03611973084a98e239fdece2d7501e2ce708
Text
12,367
142
# Compressed Stochastic Orthonormal Projective NMF (cs-opNMF) ## Introduction Accompanying code for [Taming Dimensionality in Big Neuroimaging Data: Efficient Orthonormal Projective NMF via Stochastic Learning and Data Compression](https://doi.org/10.1162/IMAG.a.1355). ## Prerequisites This code was tested on Linux...
1b7eb9156f8dfaa2dfae7dacea97fc7390ead716481f0f396d546d78cdeba56a
Text
13,027
306
# MorphoScope [![DOI](https://zenodo.org/badge/DOI/10.5281/zenodo.17901990.svg)](https://doi.org/10.5281/zenodo.17901990) [![License: MIT](https://img.shields.io/badge/License-MIT-yellow.svg)](https://opensource.org/licenses/MIT) A Python-based GUI application for quantifying structural plasticity in neuronal project...
84fd72db5c60c6ca1b1ad4c55cb342fdbf9f911b8e0c4f7e4bfa374d707bcc5e
Text
13,253
310
# SigNET: Spatial Signaling Network Analysis ## Overview **SigNET** (Signaling-to-transcription regulatory NETwork) is a computational framework for reconstructing ligand-receptor-transcription factor regulatory cascades from spatially resolved transcriptomics data. SigNET identifies co-expression patterns between th...
1bfbb828905fcc58d9ed79741aae3ec40e2fc976f1496db156a950cb7e0d66bb
Text
13,880
321
# LAMAReg: Label Augmented Modality Agnostic Registration <div align="left"> [![Version](https://img.shields.io/github/v/tag/MICA-MNI/LAMAReg)](https://github.com/MICA-MNI/LAMAReg) [![PyPI version](https://img.shields.io/pypi/v/LAMAReg.svg)](https://pypi.org/project/LAMAReg/) [![PyPI downloads](https://img.shields.io...
566febac0cae158c9db6c9a2b96b060fa0cd30bb6044869a659dd6381e85c8f2
Text
14,030
219
# Code for the paper “Probabilistic inference of Homonymous and Heteronymous Recurrent Inhibition in Human Muscles from Large-Scale Motor Neuron Recordings” bioRxiv link: https://www.biorxiv.org/content/10.64898/2025.12.19.694963v2 This repository contains: - Processing and analysis pipelines for experimental HD-EMG ...
4b6706eee9a03e323ac1a63c68d4c25249f447c2f742333b12ea680fd6da871a
Text
14,043
310
![GitHub Actions Workflow Status](https://img.shields.io/github/actions/workflow/status/Aswendt-Lab/AIDAmri/docker-image.yml) [![Static Badge](https://img.shields.io/badge/data_structure-BIDS-yellow)](https://bids.neuroimaging.io/news.html) [![Static Badge](https://img.shields.io/badge/NiftyReg-CBSI-orange)](https://gi...
a3476273556ca4e7e532c8c059cadffb0ca77817dc5521b2a1398dbba32b020f
Text
14,200
288
<!-- README.md is generated from README.Rmd. Please edit that file --> # spacexr (Spatial-eXpression-R): Robust Cell Type Decomposition (RCTD) and Cell type-Specific Inference of Differential Expression (C-SIDE) <!-- badges: start --> <!-- badges: end --> **Note**: The *spacexr* package is now available on [Biocon...
419ac0c5c9e01945bc43fdcb25cd97e4895efa3ab62b71b02d0cd3d1bc25a795
Text
15,220
389
# abCRISPR: MLP-based design of abasic gRNAs for specific genome editing using high-quality mismatch library data ## Overview abCRISPR is a deep neural network (DNN) framework for the rational design of abasic (ØXØ) gRNA sequences with minimized off-target activity. It leverages informative few-shot training on paire...
26287714ffd2d3755625f973a8e108a593be9ced2c275a7f782a56ebd9cac596
Text
15,932
251
# dcHiC: Differential Compartment Analysis of Hi-C Datasets [![License: MIT](https://img.shields.io/badge/License-MIT-green.svg)](https://opensource.org/licenses/MIT) [![DOI](https://zenodo.org/badge/274827002.svg)](https://zenodo.org/badge/latestdoi/274827002) dcHiC is a tool for differential compartment analysis o...
f5a9a3327806f13fa76088047751d8ae88fc21647c324a2bda242eb13c185e4d
Text
16,134
393
# Geode Dataset: Preprocessed Data and Analysis Guide ## Overview This repository contains a preprocessed dataset (`preprocessed_data.RData`) and comprehensive analysis code (`data_analysis_final.R`) for a study examining cognitive performance differences between typically developing (TD) and autism spectrum disorder...
cefa4c2a376247af72057747109c7cb3aa346c61c7f381643db3566e08d30f18
Text
16,272
202
# Leading Eigenvector Dynamics Analysis Toolbox - Matlab This toolbox enables the neuroscience community to apply the Leading Eigenvector Dynamics Analysis (LEiDA) method to functional MRI data with the goal of understanding brain dynamics. Below you can find a set of instructions that will guide the application of th...
add66690bd6e6bc8085d6b26639a1c048cd231b7706a3d2223bf54188d9c1087
Text
18,669
175
# MEG-SCANS: Code for Technical Validation This repository contains the code used for the technical validation and generation of plots for the MEG-SCANS (Stories, Chirps, And Noisy Sentences) dataset publication. ## Dataset and Publication The MEG-SCANS (Stories, Chirps, And Noisy Sentences) dataset provides raw mag...
40cb5584f6024ab073ec85d7904465672fd438962be82a1415fa5427f25515c6
Text
18,737
176
# MEG-SCANS: Code for Technical Validation This repository contains the code used for the technical validation and generation of plots for the MEG-SCANS (Stories, Chirps, And Noisy Sentences) dataset publication. ## Dataset and Publication The MEG-SCANS (Stories, Chirps, And Noisy Sentences) dataset provides raw mag...
ee09fa769087c388c7b4954e853be08a3b97ff325b4a6c3aa36796d421c544e9
Text
18,756
452
# Geode Dataset: Preprocessed Data and Analysis Guide ## Overview This repository contains a preprocessed dataset (`preprocessed_data.RData`) and comprehensive analysis code (`data_analysis_final.R`) for a study examining cognitive performance differences between typically developing (TD) and autism spectrum disorder...
51ece04bd199211fec441a33e39ceabc5e68f63d7d50aed82fb66490a55d8531
Text
18,758
320
[![install with bioconda](https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat)](https://anaconda.org/bioconda/accusnv) # <img src="readme_files/logo.png" width = "100" height = "100" > High-accuracy SNV calling for bacterial isolates using AccuSNV ### Version: V1.1.2 (Last update on 2026...
4cf8398f7d56f4ff0389b5d341ed9949ae741088bd3f17eea98da6feceababec
Text
19,238
442
# SMILES2Docking **[English](#english) | [Português](#português)** --- ## English Desktop application and Python workflow for preparing ligands from `CSV`, `XLS`, and `XLSX` spreadsheets. The pipeline performs structural curation, multi-site protonation at configurable pH, 3D generation with `RDKit ETKDGv3`, force-...
1e8797569bf2ba776d420c1f487868ffd9e7a203ef4dc4de0a7c9a53da30368c
Text
19,252
574
# Single-cell RNA-sequencing analyses of neonatal mouse microglia This repository contains the analysis code supporting a study of early postnatal microglial states in mice under physiological conditions and following neonatal lipopolysaccharide challenge. The workflow includes primary single-cell RNA-sequencing proce...
14b5b84eddbfc06ea0398eb12c448bc2a230502d4e2b812fab7590ea57ea1294
Text
19,458
170
# alps.sh This is a ```bash``` script that automatically computes the diffusion along perivascular spaces (ALPS) metric from diffusion-weighted images (```dwi```). The ALPS index has been described by [Taoka et al. (Japanese Journal of Radiology, 2017)](https://link.springer.com/article/10.1007/s11604-017-0617-z) ...
682ff39b9fee02d391dcd4a71c86c6a81374c5d91a898c524591046d10ebc7eb
Text
23,438
805
# Supplementary Material: Coupled Cardiac System ## Overview We present a software package designed for a coupled cardiac system that integrates real-time 2D cardiac simulations—implemented using the WebGL-based Abubu.js library—with living cardiac monolayers via a fully optical interface. This documentation provides...
5c8ea392dc231a6dfe044bd85a637f89b458d9afdabdf74ac2b3dbb96c9b54f8
Text
24,382
430
# Neuromuscular Junction (NMJ) Analysis Pipeline This pipeline was used in *Self-organization of vascularized muscle from bovine embryonic stem cells*. AI tools (Cursor and Antigravity) assisted with code and documentation. The authors reviewed, tested, and modified the generated code and manually verified results by ...
6b11f79a3f28773868c133de0cf1391a54895b0563abf8ffc4687f8b31aae7c7
Text
25,125
535
# CASCADE v0.8.0 **Criticality Avalanche Spike Cross-platform Analysis Detection Engine** CASCADE is a modular Python pipeline for analysing multi-electrode array (MEA) recordings from multiple manufacturers. It reads manufacturer-specific spike files, converts them into a common internal format, and runs a standardi...
6ff34ec33f7e5f15a027a551fa747716442c43f370eddfa9bc132c7bde530f83
Text
25,292
539
# CASCADE v0.8.0 **Criticality Avalanche Spike Cross-platform Analysis Detection Engine** <div align="center"> <img width="250" height="250" alt="CASCADE_Logo" src="https://github.com/user-attachments/assets/7a029bf6-93b7-4185-8859-888672b4bb65" /> </div> CASCADE is a modular Python pipeline for analysing multi-elec...
8436ad32834b3c55730c5a2753fa91d24e7ef4aae1623dc5c32a3153b395fdf1
Text
25,415
403
# Scheib_2026 Code and data repository for the Scheib et al., 2026 manuscript in eLife from the Kerlin Lab at the University of Minnesota, Twin Cities. The repository contains the per-animal behavioral and two-photon calcium-imaging data used in the study, the pre-computed trace alignments and example-ROI exports the...
48810a205857a3c8abb11516536513171f2ea821e7f6297cb6b0b936a33c01fa
Text
25,935
446
# ECLIPSE — Dark Proteome Exploration of ESKAPE Pathogens **ECLIPSE** (ESKAPE Connectome Linkage and Inference for Proteome Sequence Exploration) is a modular computational pipeline for the systematic identification and prioritisation of functionally ("dark") protein families in ESKAPE panproteomes. ECLIPSE maps ESKA...