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####################################################################################################### # =================================================================================================== # Function for pathway analysis # ===============================================================================...
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R
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## BiomarkerInputs <- function(id) { ns <- shiny::NS(id) ## namespace bigdash::tabSettings( class = "p-1", shiny::tagList( withTooltip( shiny::selectInput(ns("pdx_ta...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## ##=================================================================== ##================ Script to build PGX object ======================= ##==============================================...
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--- title: "Figure 2G-K, O, P: IT Neuron Archetype Analysis and Cross-Species Projection" output: --- ```{r setup, include=FALSE} # This sets the project root based on the repo structure. # If you move this file, you may to set the root manually to find config.R knitr::opts_knit$set(root.dir = dirname(dirname(rstudioa...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## enrichment_plot_volcanoall_ui <- function( id, title, info.text, info.methods, info.references, info.extra_link, caption, height, width ) { ns <- shiny::NS(id) plot_...
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R
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## compare_plot_genecorr_ui <- function( id, title, info.text, label = "", height = c(600, 800) ) { ns <- shiny::NS(id) genecorr.opts <- shiny::tagList( withTooltip( ...
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R
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## #' Mechanism-of-action plot UI input function #' #' @description A shiny Module for plotting (UI code). #' #' @param id #' @param label #' @param height #' #' @export mofa_report_summary_u...
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R
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## dataview_plot_tsne_ui <- function( id, label = "", title, height, width, caption, info.text, info.methods, info.references, info.extra_link ) { ns <- shiny::NS(id) ...
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R
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--- title: "2c. Opossum, Label Nonneuronal" output: --- ```{r setup, include=FALSE} # This sets the project root based on the repo structure. # If you move this file, you may need to set the root manually to find config.R knitr::opts_knit$set(root.dir = dirname(dirname(rstudioapi::getSourceEditorContext()$path))) kni...
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R
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## #' Expression plot UI input function #' @description A shiny Module for plotting (UI code). #' @param id #' @param label #' @param height #' @param width #' @export expression_plot_volcano...
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R
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## #' Expression plot UI input function #' #' @description A shiny Module for plotting (UI code). #' #' @param id #' @param label #' @param height #' @param width #' #' @export expression_plo...
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R
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####################################################################################################### # =================================================================================================== # # Auxillar function for coMethDMR # ============================================================================...
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R
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args=commandArgs(trailingOnly=TRUE) #-------------------------------------------------------------------------------------------------------------------------------------- # Extract single-cell copy-number variation based on MosaiCatcher result for normalization purpose (lenient call from mosaicatcher) #-------------...
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################# ### Load data ### ################# rm(list=setdiff(ls(),c('params','grp'))) basedir <- params$basedir setwd(basedir) savedir <- paste(params$opdir,'sncamodel/',sep='') dir.create(savedir,recursive=T) dir.create(paste(savedir,'roilevel',sep=''),recursive = T) source('code/fitfxns.R') load(paste(para...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## #' Expression plot UI input function #' #' @description A shiny Module for plotting (UI code). #' #' @param id #' @param label #' @param height #' #' @export expression_plot_volcanoAll_ui ...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## LasagnaInputs <- function(id) { ns <- shiny::NS(id) ## namespace bigdash::tabSettings( shiny::selectInput(ns("contrast"), "Select comparison", choices = NULL), shiny::selectInp...
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--- title: "2b. Opossum, Label GABAergic" output: --- ```{r setup, include=FALSE} # This sets the project root based on the repo structure. # If you move this file, you may need to set the root manually to find config.R knitr::opts_knit$set(root.dir = dirname(dirname(rstudioapi::getSourceEditorContext()$path))) knitr...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## LasagnaBoard <- function(id, pgx) { moduleServer(id, function(input, output, session) { ns <- session$ns ## NAMESPACE fullH <- 700 ## full height of page rowH1 <- 250 ## row ...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## #' Mechanism-of-action plot UI input function #' #' @description A shiny Module for plotting (UI code). #' #' @param id #' @param label #' @param height #' #' @export drugconnectivity_repo...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## #' Create UI for top enriched gene set plots #' #' @description #' Generates the Shiny UI for plotting the top enriched gene sets. #' #' @param id Widget id to use for the output. #' @par...
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library(ggplot2) library(dplyr) library(showtext) library(hrbrthemes) library(stats) # Add Google fonts font_add_google("Outfit", "title_font") font_add_google("Cabin", "body_font") showtext_auto() title_font <- "title_font" body_font <- "body_font" # Create the directory if it doesn't exist if (!dir.exists("demogra...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## #' Single cell plot UI input function #' #' @description A shiny Module for plotting (UI code). #' #' @param id #' @param label #' @param height #' @param width #' #' @export singlecell_pl...
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# Genotype library(ggplot2) library(reshape) library(dplyr) library(tibble) source('workflow/scripts/arbigent/clean_genotype_defs.R') source('workflow/scripts/arbigent/vcf_defs.R') # but first explore runname = 'review_david323' debug_file = paste0('~/PhD/projects/huminvs/mosaicatcher/analysis/results/', runname, '/ms...
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# ============================================================ # Script 04: Spearman Rank Correlation Analysis # Candrea et al. - Gut Microbiota Comparative Analysis # Biomedicines 2025 # ============================================================ # Description: # Spearman rank correlation analysis between microbial t...
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sideBarLoadData <- function(){ #Load basic gwas data for sidebar gwas_risk_variants <<- fread("www/summarystats/gwas_risk_variants.csv") #gwas_id_string <- "META5" gwas_info <<- fread("www/summarystats/gwasInfo.csv") #build the gwas_list that will hold names and values for the "Choose a GWAS" drop...
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############################################################################### # Renamed Functions (same behavior/IO as originals) ############################################################################### # ---------- small helpers ---------- .melt_mat <- function(mat) { mat <- as.matrix(mat) data.frame( ...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## featuremap_plot_gene_map_ui <- function( id, title, info.text, info.methods, info.references, info.extra_link, caption, label = "", height, width ) { ns <- shiny::NS(...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## upload_module_received_ui <- function(id, height = 720) { ns <- shiny::NS(id) } upload_module_received_server <- function(id, auth, ...
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R
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#!/usr/bin/env Rscript # RNA-seq Pipeline Step 6: Functional Enrichment Analysis (GO and KEGG) # This script performs Gene Ontology and KEGG pathway enrichment analysis suppressPackageStartupMessages({ library(clusterProfiler) library(org.Hs.eg.db) library(enrichplot) library(ggplot2) library(tidy...
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--- title: "Mouse Spatial Preprocessing: Subset and Combine Columns" output: --- ```{r setup, include=FALSE} # This sets the project root based on the repo structure. # If you move this file, you may need to set the root manually to find config.R knitr::opts_knit$set(root.dir = dirname(dirname(rstudioapi::getSourceEdi...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## ##=================================================================== ##================ Script to build PGX object ======================= ##==============================================...
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#!/usr/bin/env Rscript suppressPackageStartupMessages(library(argparser)) suppressPackageStartupMessages(library(magrittr)) parser <- arg_parser("detect translocation hotspots using scan statistics", name="TranslocHotSpots.R") %>% add_argument("tlxfile", "input tlx file of t...
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## Complete Pipeline for Driver Estimation and Master Table Creation ## ############### Step 0: Preparation ############### # Load NetBID2 package library(NetBID2) # Get the demo's constructed network data network.dir <- sprintf('%s/demo1/network/',system.file(package = "NetBID2")) # use demo network in the ...
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--- title: "Opossum Spatial Preprocessing: Subset and Combine Columns" output: --- ```{r setup, include=FALSE} # This sets the project root based on the repo structure. # If you move this file, you may need to set the root manually to find config.R knitr::opts_knit$set(root.dir = dirname(dirname(rstudioapi::getSourceE...
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title: "Female_PCB_Cortex" author: "Osman Sharifi" library(Seurat) library(biomaRt) library(scCustomize) library(ggplot2) ### The percentage of reads that map to the mitochondrial genome # We use the set of all genes, in mouse these genes can be identified as those that begin with 'mt'. #load data load("/Users/osm...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## FeatureMapInputs <- function(id) { ns <- shiny::NS(id) ## namespace bigdash::tabSettings( ## data set parameters withTooltip( shiny::radioButtons( ns("showvar"), ...
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--- title: "HUDECA — Extended Data Figure 2: Quality control of human olfactory epithelium snRNA-seq data" author: "Mbouamboua Yvon <yvon.mbouamboua@inserm.fr>" output: html_document: toc: true toc_float: true number_sections: true date: '`r format(Sys.Date())`' --- ## Goal Final figures ## Setup ```{r ...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## CorrelationInputs <- function(id) { ns <- shiny::NS(id) ## namespace bigdash::tabSettings( withTooltip(shiny::selectInput(ns("gene"), tspan("Gene:"), choices = NULL), "Choose...
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# Load packages library(readxl) library(dplyr) library(ggplot2) # Get a list of all directories all_directories <- list.dirs(path = "/Users/osman/Documents/GitHub/PEBBLES_mouse_snRNAseq/soupx", full.names = TRUE) # Create an empty data frame to store the combined data combined_data <- data.frame() # Loop through eac...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## MofaBoard <- function(id, pgx) { moduleServer(id, function(input, output, session) { ns <- session$ns ## NAMESPACE fullH <- 700 ## full height of page rowH1 <- 250 ## row 1 ...
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R
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library(data.table) library(coloc) Ferr <- fread("Ferritin_AF0p005.mr_ready.tsv.gz") # Opening primary panel primary <- fread("2019-12-11-cis-eQTLsFDR-ProbeLevel-CohortInfoRemoved-BonferroniAdded.txt.gz") # Opening the proxy panel proxy1 <- fread("GTEx_Analysis_v8_eQTL/Whole_Blood.v8.signif_variant_gene...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## #' Drug Connectivity plot UI input function #' #' @description A shiny Module for plotting (UI code). #' #' @param id #' @param label #' @param height #' #' @export drugconnectivity_plot_c...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## ##=================================================================== ##================ Script to build PGX object ======================= ##==============================================...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## clustering_plot_clusterannot_ui <- function( id, label = "", title, info.text, info.methods, info.references, info.extra_link, caption, height, width ) { ns <- shiny:...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## ##=================================================================== ##================ Script to build PGX object ======================= ##==============================================...
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## load required libraries library(GenomicAlignments) library(ggplot2) library(cowplot) library(BiocParallel) #' Print haplotagged read counts #' #' This function will take \code{list} of haplotagged bams files and will return \link{data.frame} #' counts of reads per haplotype. #' #' @param sv.table A path to a table ...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## ## -------------------------------------------------------------------------- ## convert list of checks to html tags for display in the data preview modal ## -----------------------------...
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#!/usr/bin/env Rscript # Generate Complete Differential Expression Table # This script creates a comprehensive publication-ready table with all detected genes # and explicit fold change direction annotations # Using base R - no packages needed cat("==========================================\n") cat("Generating Compl...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## ConsensusWGCNA_Board <- function(id, pgx) { moduleServer(id, function(input, output, session) { ns <- session$ns ## NAMESPACE fullH <- 700 ## full height of page rowH1 <- 250...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## PathwayBoard <- function(id, pgx, selected_gsetmethods = reactive(colnames(pgx$gset.meta$meta[[1]]$fc))) { moduleServer(id, function(inp...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## ConnectivityInputs <- function(id) { ns <- shiny::NS(id) ## namespace bigdash::tabSettings( withTooltip( shiny::selectInput(ns("contrast"), "Contrast:", choices = NUL...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## #' Expression plot UI input function #' #' @description A shiny Module for plotting (UI code). #' #' @param id #' @param label #' @param height #' #' @export signature_plot_volcano_ui <- f...
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# # Copyright (c) 2018 German Cancer Research Center (DKFZ). # # Distributed under the MIT License (license terms are at https://github.com/DKFZ-ODCF/AlignmentAndQCWorkflows). # ################## ## start Daniel ## ################## extractFWHM <- function(ratio_density){ half_max_ratio_density <- max(ratio_densi...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## #' Single cell plot UI input function #' #' @description A shiny Module for plotting (UI code). #' #' @param id #' @param label #' @param height #' @param width #' #' @export singlecell_pl...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## DrugConnectivityInputs <- function(id) { ns <- shiny::NS(id) ## namespace bigdash::tabSettings( withTooltip(shiny::selectInput(ns("contrast"), "Contrast:", choices = NULL), "...
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####################################################################################################### # =================================================================================================== # # Function for plot # =========================================================================================...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## InviteFriendUI <- function(id) { ns <- shiny::NS(id) shiny::actionButton( ns("action"), "Invite!", width = "auto", class = "quick-button" ) } InviteFriendModule <- function(...
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#========== # Univariate twin model: trial-level missing # # author: Giorgia Bussu # project: BT missing data # version: June 2024 #================================================= rm(list=ls()) ### set a working directory (otherwise create a new R project): setwd('C:/Users/myfolder/missingdata_BATSS...
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#################### ## Load libraries ## #################### library(magrittr) library(VennDiagram) library(grDevices) library(dplyr) library(Seurat) library(glue) library(scCustomize) library(edgeR) library(ggplot2) library(ggrepel) library(GeneOverlap) library(enrichR) ################## ## Load samples ## ########...
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--- title: "QC plot for network generated by SJAracne" output: html_document --- ```{r include=FALSE} library(NetBID2) library(kableExtra) ``` ```{r echo=FALSE} deg <- igraph::degree(net,mode='out') source_list <- names(deg)[which(deg>0)] full_info <- FALSE if(html_info_limit==FALSE) full_info<-TRUE c1 <- componen...
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#################### ## Load libraries ## #################### library(magrittr) library(VennDiagram) library(grDevices) library(dplyr) library(Seurat) library(glue) library(scCustomize) library(edgeR) library(ggplot2) library(ggrepel) library(GeneOverlap) library(enrichR) ################## ## Load samples ## ########...
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#################### ## Load libraries ## #################### library(magrittr) library(VennDiagram) library(grDevices) library(dplyr) library(Seurat) library(glue) library(scCustomize) library(edgeR) library(ggplot2) library(ggrepel) library(GeneOverlap) library(enrichR) ################## ## Load samples ## ########...
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## #' Expression plot UI input function #' @description A shiny Module for plotting (UI code). #' @param id #' @param label #' @param height #' @param width #' @export TimeSeriesBoard.feature...
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#################### ## Load libraries ## #################### library(magrittr) library(VennDiagram) library(grDevices) library(dplyr) library(Seurat) library(glue) library(scCustomize) library(edgeR) library(ggplot2) library(ggrepel) library(GeneOverlap) library(enrichR) ################## ## Load samples ## ########...
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#################### ## Load libraries ## #################### library(magrittr) library(VennDiagram) library(grDevices) library(dplyr) library(Seurat) library(glue) library(scCustomize) library(edgeR) library(ggplot2) library(ggrepel) library(GeneOverlap) library(enrichR) ################## ## Load samples ## ########...
7b85facfa1fd7ecda3173a09dafd5704c204c7918db53de50f600d83a6cdee2a
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## ##=================================================================== ##================ Script to build PGX object ======================= ##==============================================...
8b09c8a10ddc0b7c5d9fa6e3f226af9eb58c02b5d4d48b2e91016aed76969f6b
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## #' Single cell plot UI input function #' #' @description A shiny Module for plotting (UI code). #' #' @param id #' @param label #' @param height #' @param width #' #' @export singlecell_pl...
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#################### ## Load libraries ## #################### library(magrittr) library(VennDiagram) library(grDevices) library(dplyr) library(Seurat) library(glue) library(scCustomize) library(edgeR) library(ggplot2) library(ggrepel) library(GeneOverlap) library(enrichR) ################## ## Load samples ## ########...
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#################### ## Load libraries ## #################### library(magrittr) library(VennDiagram) library(grDevices) library(dplyr) library(Seurat) library(glue) library(scCustomize) library(edgeR) library(ggplot2) library(ggrepel) library(GeneOverlap) library(enrichR) ################## ## Load samples ## ########...
0e4d7f2aab4462ec2b9a30238cd3ed6a59b6bc39a418c893008015d3d43134da
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#################### ## Load libraries ## #################### library(magrittr) library(VennDiagram) library(grDevices) library(dplyr) library(Seurat) library(glue) library(scCustomize) library(edgeR) library(ggplot2) library(ggrepel) library(GeneOverlap) library(enrichR) ################## ## Load samples ## ########...
9e5d8ec1d3059a8ed9835c18a0c813c864f9d110bd9a77bf1474a4d8aebf3e2f
R
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#################### ## Load libraries ## #################### library(magrittr) library(VennDiagram) library(grDevices) library(dplyr) library(Seurat) library(glue) library(scCustomize) library(edgeR) library(ggplot2) library(ggrepel) library(GeneOverlap) library(enrichR) ################## ## Load samples ## ########...
e56816b4f8476ef1159a64e9844b0964756a08161bffeba5eeb51af2b1446553
R
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## ##=================================================================== ##================ Script to build PGX object ======================= ##==============================================...
e114860ca6ee3465969a472e97afd233dc0b63fa15980b65b6e01d8f2f1ce924
R
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#################### ## Load libraries ## #################### library(magrittr) library(VennDiagram) library(grDevices) library(dplyr) library(Seurat) library(glue) library(scCustomize) library(edgeR) library(ggplot2) library(ggrepel) library(GeneOverlap) library(enrichR) ################## ## Load samples ## ########...
7e3d71e8fdc785992c896534684c4fafe72dcf4af272f082764104c7bdc86dd9
R
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## featuremap_plot_geneset_map_ui <- function( id, label = "", title, info.text, info.methods, info.references, info.extra_link, caption, height, width ) { ns <- shiny::...
d10ee4a84cc7ae5914be065f0c54370601a4584ac648c9dacb2a7ab7e25e9b13
R
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## CompareInputs <- function(id) { ns <- shiny::NS(id) ## namespace bigdash::tabSettings( withTooltip( shiny::selectInput(ns("contrast1"), "Dataset1:", choices = NULL, m...
70d0fc2b7e975067baa51024869771a13b95475808390df493c2e202dc2211d1
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#################### ## Load libraries ## #################### library(magrittr) library(VennDiagram) library(grDevices) library(dplyr) library(Seurat) library(glue) library(scCustomize) library(edgeR) library(ggplot2) library(ggrepel) library(GeneOverlap) library(enrichR) ################## ## Load samples ## ########...
c98f039cf430d91caf51a8dbbcda03cfa0b17407ee60684aa5708be9fd33b3ed
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######################################### ### Taylor-Bateman et al., 2025 - Repurposing drugs for the prevention of vascular dementia: Evidence from drug target Mendelian randomization ### Cis&Trans_DTMR.R requires 2 input files ### An Exposure protein GWAS - ### An Outcome GWAS Exposure_GWAS <- Outcome_GWAS <-...
3584ef77dc53746233ec7bd2930b1aa2fdf86f0ba14dd95faada56d3ee5706ca
R
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## CorrelationBoard <- function(id, pgx, labeltype = shiny::reactive("feature")) { moduleServer(id, function(input, output, session) { ns <- session$ns ## NAMESPACE fullH <- 800 ##...
bfa0c00a9822819d953a1e48aafd599dcaf0f33ab0778cd8039cc12864e6fb27
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######################################################## ## Create broad categories and run mosiacism analysis ## ######################################################## library(magrittr) library(VennDiagram) library(grDevices) library(dplyr) library(Seurat) library(glue) library(scCustomize) library(edgeR) library(gg...
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R
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######################################################## ## Create broad categories and run mosiacism analysis ## ######################################################## library(magrittr) library(VennDiagram) library(grDevices) library(dplyr) library(Seurat) library(glue) library(scCustomize) library(edgeR) library(gg...
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R
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######################################################## ## Create broad categories and run mosiacism analysis ## ######################################################## library(magrittr) library(VennDiagram) library(grDevices) library(dplyr) library(Seurat) library(glue) library(scCustomize) library(edgeR) library(gg...
9f24247571ad356f264c4a4f689e151bce206e920672fdfa1e8bc2fbd86f7a5f
R
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# Whoeps, 07th Jan 2021 # Making a large overview over the results from the arbigent folder. # I'm giving myself 2h to make this nice today. # Input: callmatrix from clean_genotype.R # Input: a csv from david from which to extract samplenames # Output: a matrix with added entries: # Filter - Pass, NoReadsPass, Mende...
3f28d7739d61bc8bc57482f8f6666cf81af46f59b96d09059ecf677b66cef910
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--- title: "Integration of in vitro hGPCs and Fetal scRNA-seq" author: "John Mariani" date: "07/30/2025" output: github_document --- ```{r setup, include=FALSE} knitr::opts_chunk$set(echo = TRUE) knitr::opts_knit$set(root.dir = rprojroot::find_rstudio_root_file()) ``` ```{r, echo = TRUE, message=FALSE, warning=FALSE...
8c83bdf169a4c57314a51f1f1a76b0cf3b78ba681be2cd8a349409fb3a4432b7
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library(GenomicRanges) library(rtracklayer) library(tidyverse) library(ChIPseeker) library(TxDb.Mmusculus.UCSC.mm10.knownGene) library(org.Mm.eg.db) library(clusterProfiler) library(ggplot2) library(gridExtra) # Initialize txdb object txdb <- TxDb.Mmusculus.UCSC.mm10.knownGene # Parse command line arguments library(o...
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## library(dotenv) ## library(shiny) ## library(shinychat) ## library(bslib) CopilotUI <- function(id, layout = c("sidebar", "fixed")[1]) { ns <- shiny::NS(id) sections <- c( "description", "dataset_info", "compute_settings", "differential_expression", "geneset_enrichment", "drug_similarity", "pcsf_re...
07051556ac259daf1ce23a0f530645e3f7a73bcb35caec6c86b04aeeecd13622
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--- title: "2a. Opossum, Label Glutamatergic" output: --- ```{r setup, include=FALSE} # This sets the project root based on the repo structure. # If you move this file, you may need to set the root manually to find config.R knitr::opts_knit$set(root.dir = dirname(dirname(rstudioapi::getSourceEditorContext()$path))) kn...
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urmet <- read.delim("raw/urine_metabolome/urine_metabs.csv", row.names = 1, sep = ",", check.names = FALSE) urmet <- urmet %>% dplyr::select(!Group) urmet[,-c(1:3)] <- urmet[,-c(1:3)] %>% t() %>% Tjazi::clr_c() %>% t() urmet_df_long <- urmet %>% pivot_longer(!c(ID, visit, Coffee_Type)) %>% mutate(Visit = c...
34f7190eb7dd6f5ea8bc0b50d50b639e82a055842a9951e65273b476bb665c1c
R
10,564
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library(reshape2) library(ggplot2) my.clinical <- function() { id_clinical=read.delim("als_id_clinical.tsv",header=F,stringsAsFactors=F) colnames(id_clinical)=c("ID","Individual","TargetID","Gender","Cogdx","Cogdx2","FTD","Age","Tissue","RIN","PMI","C9expansion") id_clinical$Cogdx[grepl("ALS Spectrum MND",id...
5b304ee1d84328af857070618ec2aca48b13c8b84264534bd0d2f8b078bbcea0
R
10,609
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evidence_section<-list() evidence_section$id <- "evidence" evidence_section$title <- "Evidence Per Gene" evidence_section$loadData<- function(){ ######create a dataframe to hold the conclusion values. This will need to contain extra info for genes on loci with multiple risk snps (like locus 1) which is why we mer...
b61309b18f4ba0d0388477b0ed34c831d4a6eeaa66cf73970aae9f523503779d
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library(data.table) ## 2016 #### # spatial transcriptomics #### ST_OB_data_1 = list( dataset = 'ST_OB1', spatial_locs = "https://raw.githubusercontent.com/drieslab/spatial-datasets/master/data/2016_ST_olfactory_bulb/cell_locations/Rep11_MOB_0_location.txt", expr_matrix = "https://raw.githubusercontent.com/dri...
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R
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log <- file(snakemake@log[[1]], open = "wt") sink(file = log, type = "message") sink(file = log, type = "output") # IMPORTS library(ComplexHeatmap) library(RColorBrewer) library(dplyr) library(tidyr) # pdf("TEST_R_dev.pdf", width = 20, height = 10) pdf(snakemake@output[["pdf"]], width = 20, height = 10) # Chromos...
7387f15174d94f8baf5d66c08c6fa60e2fc027a2b69b0dd54d9f8232f5d358e5
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## ## ============================================================================= ## ==================== BATCHCORRECT UI/SERVER ================================= ## ======================...
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######################################### ### Taylor-Bateman et al., 2025 - Repurposing drugs for the prevention of vascular dementia: Evidence from drug target Mendelian randomization ### GColoc_DTMR.R requires 2 input files ### An Exposure GWAS ### An Outcome GWAS Exposure_GWAS <- Outcome_GWAS <- ### Column ...
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R
10,685
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# Time-resolved decoder comparison using sliding-window random forests. # # Expected input: # - Two CSV files (e.g. "WTdata.csv" and "DGLcKOdata.csv") with one trial per row. # - All columns except the last are time-resolved features. # - The last column contains the class label for each trial (e.g., "escape", "avoidan...
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10,806
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######################################### ### Taylor-Bateman et al., 2025 - Repurposing drugs for the prevention of vascular dementia: Evidence from drug target Mendelian randomization ### CisLT_DTMR.R requires 2 input files ### An Exposure GWAS ### An Outcome GWAS Exposure_GWAS <- Outcome_GWAS <- ### Column ...
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R
10,842
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--- title: "HUDECA — Figure 6: Analysis of the expression of the olfactory receptors (ORs) in the fetal human olfactory system" author: "Mbouamboua Yvon <yvon.mbouamboua@inserm.fr>" output: html_document: toc: true toc_float: true number_sections: true date: '`r format(Sys.Date())`' --- ## Goal Final fig...
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R
10,851
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# %% Load libraries and load data suppressPackageStartupMessages({ library(readr) library(dplyr) library(gtsummary) library(forcats) library(gt) library(knitr) library(purrr) library(kableExtra) }) here::i_am("code/make_variable_tables.R") library(here) results_path <- here("results", "reproduced") dat...
d74fbd043bae1c94a7762102d51f11677dcb738dec5a7231ad77cd658220b151
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## ## This file is part of the Omics Playground project. ## Copyright (c) 2018-2026 BigOmics Analytics SA. All rights reserved. ## WgcnaBoard <- function(id, pgx) { moduleServer(id, function(input, output, session) { ns <- session$ns ## NAMESPACE fullH <- 700 ## full height of page rowH1 <- 250 ## row 1...
90d6f4759ca0cd5b31c077718a4fba49a4cd053fb72508617efb0bd2599f3800
R
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--- title: "Figure 1G-K: Class and Subclass Proportions" output: --- ```{r setup, include=FALSE} # This sets the project root based on the repo structure. # If you move this file, you may need to set the root manually to find config.R knitr::opts_knit$set(root.dir = dirname(dirname(rstudioapi::getSourceEditorContext(...
6c880082a5582eb2ad37715544d71f98bb5c0d3b719038a5afcc1ce2049d49be
R
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library(R.matlab) library(tidyverse) library(ggplot2) library(gridExtra) library(refund) library(dplyr) # read data and extract variable names setwd("~/Desktop/NIMH Research/Causal/DA_adapts_learn_rate") matdat <- R.matlab::readMat("seshMerge.mat") matdat <- matdat$seshMerge # indices in dataset of variables photo_id...