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R
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#'--- #' title: Create GeneID-GeneName mapping #' author: mumichae #' wb: #' log: #' - snakemake: '`sm str(tmp_dir / "MAE" / "{annotation}.Rds")`' #' input: #' - gtf: '`sm lambda w: cfg.genome.getGeneAnnotationFile(w.annotation) `' #' output: #' - gene_name_mapping: '`sm cfg.getProcessedDataDir() + "/mae/gene_...
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R
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#' Mouse Hippocampus VeraFISH data #' #' This dataset comprises VeraFISH profiling of cells in the mouse hippocampus. #' Gene expression and cell centroids for 10,944 cells and 129 genes in 2 #' spatial dimensions are provided. For details on how this dataset was #' generated, refer to Supplementary Information sectio...
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R
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#!/usr/bin/env RScript args=commandArgs(trailingOnly=TRUE) # usual functions lire<-function(x, character=FALSE){ if(character){ d<-read.table(file = x,sep = "\t",header=T,row.names = 1,colClasses = "character",quote="",check.names=FALSE) }else{ d<-read.table(file = x,se...
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R
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frb_scatter <- combined_mods %>% ggplot(aes(x = truth, y = corrected_pred, color = corrected_gap)) + # abline of true age above other elements for vis geom_abline(lty = 1, color = "#cccccc", size = 1.2) + geom_point(size = 5, alpha = 0.5) + # linear trend of mod geom_smooth( method = lm, formula = y ~...
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R
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#' #' The Banksy package #' #' Banksy is a library and R package for network analysis. #' #' @rdname Banksy-package #' @name Banksy-package #' @keywords internal #' @aliases Banksy-package Banksy #' @docType package #' @useDynLib Banksy, .registration = TRUE #' @importFrom Rcpp sourceCpp #' #' @section Description: #' ...
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R
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#' @title Create Sankey Diagram #' @description Generates a Sankey diagram to visualize flows or relationships between nodes. #' Uses the `networkD3` package. #' @param links Data frame containing 'source', 'target', 'value', and optionally 'color' columns. #' @return A Sankey diagram widget (networkD3 object). sa...
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R
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# extract.parametrs = function(fit, name_of_model, # parameters.to.extract = c('chisq', 'df', 'pvalue', # 'cfi',"tli",'rmsea',"rmsea.ci.lower", # "rmsea.ci.upper", 'srmr')) { # i...
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R
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# Pure functions shared by analysis and checks. assert_design <- function(md,formula) { mm <- model.matrix(formula,md) if(qr(mm)$rank<ncol(mm) || nrow(mm)<=ncol(mm)) stop('Nonestimable or saturated design') invisible(mm) } make_rank <- function(values,symbols) { keep <- is.finite(values)&!is.na(symbols)&nzchar(...
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R
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# In this script we will be gathering pathology diagnosis # and pathology free text diagnosis terms to select EPN # samples for following EPN subtyping analysis and save # the json file in EPN-subset folder library(tidyverse) ## Directories root_dir <- rprojroot::find_root(rprojroot::has_dir(".git")) output_dir <-...
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R
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context("geom_polygon_auc") test_that("geom_polygon_auc works", { test_geom_polygon_auc_screenshot <- function() { print(ggroc(r.s100b) + geom_polygon_auc(r.s100b$auc)) } expect_ggroc_doppelganger("geom_polygon_auc.screenshot", test_geom_polygon_auc_screenshot) }) test_that("geom_polygon_auc works with perc...
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R
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####################################### # # This function is used to obtain the # time delay projecton maps from inputs # while matching the selected participants # # This function can load the data of TDp and # ETS. Indicates what kinds of data you want to # load in [type] parameter ObtainBrainData <- fun...
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R
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library(openxlsx) # import excel file library(reshape2) # reshape data library(ggplot2) # plots library(lmerTest) # linear mixed model library(emmeans) # multiple comparisons donnees <- read.xlsx("anatExt_decodAccu.xlsx") donnees$subID <- factor(donnees$subID) donnees <- melt(donnees) donnees$FoR <- sub("_.*", "", d...
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R
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source("../shinytest_helpers.R") set_window() app$setInputs(layout_and_readouts = "separate_files") app$uploadFile(layout_table_file = demo_path("CRA_Layout.xlsx")) app$uploadFile(readout_matrices_file = demo_path("CRA_1ReadoutXlsx_INF-R-1632.zip")) app$setInputs(type_of_analysis = "StepA") app$setInputs(iTReX = "QCN...
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R
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################################################################################ # Determines if a gene expression plot should be created. # # The event reactive that triggers creating a gene expression plot is based on # the Show plots button being clicked and Gene Expression option being chosen. # The logic is compli...
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R
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# designed to run on a _single_ parcel-beta make_rdms_from_beta <- function (path_parcel_beta) { betas <- read_csv(path_parcel_beta) # in case the ROI has 0 voxels? which happens apparently? if (nrow(betas) == 0) return (NULL) roi <- str_sub(basename(path_parcel_beta), start = 7L, end = -5L) betas ...
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R
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test_that("NCBI_synonyms2023 maps aliases to official symbols using a supplied annotation", { # tiny synthetic annotation with the required column order: # Symbol (2), all_synonyms (3), GeneID (4), ENSG_ID (5) annotation <- data.frame( rows = 1:4, Symbol = c("PTGER3", "PTGER3", "SNTB2", "TP5...
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--- title: "R Notebook" output: html_notebook --- ## Load merged gene symbol + ENSG mapping file and PMTL file ```{r} library(tidyverse) ens_map <- read_tsv("results/gencode_ensg_symbol_map_merged.tsv") %>% rename(ensg_id = ensembl) pmtl <- read_tsv("input/PMTL_v3.1.tsv") %>% rename(ensg_id = Ensembl_ID, pmtl = F...
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R
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rm(list = ls()) library(ggplot2) library(openxlsx) library(tidyverse) go_enrich = read.xlsx('metascape_result.xlsx', sheet = 2)#read enrichment analysis result go_enrich <- go_enrich[grepl("Summary", go_enrich$GroupID), ] go_enrich <- go_enrich[1:10,] go_enrich$term <- paste(go_enrich$Term, go_enrich$Description...
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R
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setwd("/data/wuqinhua/phase/covid19/datasets") library(Seurat) library(SeuratDisk) sce1 = readRDS("./pre_data/9_Schulte-Schrepping_2020/seurat_COVID19_PBMC_cohort1_10x_jonas_FG_2020-08-15.rds") sce2 = readRDS("./pre_data/9_Schulte-Schrepping_2020/seurat_COVID19_PBMC_jonas_FG_2020-07-23.rds") sce1@meta.data <- as.data...
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R
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library(Biobase) library(GEOquery) library(Seurat) library(readxl) library(ggplot2) library(dplyr) library(harmony) library(GenomicRanges) library(Seurat) library(patchwork) library(cowplot) library(data.table) library(scales) library(org.Hs.eg.db) library(rtracklayer) getGEOSuppFiles('GSE76381', baseDir="downloads...
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R
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#' Batch Correction with SVA #' #' This function will do batch correction on mvalues, #' #' @param mval matrix of mvalues #' @param pdata sample Sheet (dataframe) #' @param model model to apply with sva (string) eg: "~group+gender" #' #' @return A matrix of batch corrected mvalues #' #' @importFrom sva sva #' @importFr...
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R
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library(tidyr) library(dplyr) library(ggplot2) library(lme4) library(lmerTest) library(performance) #setwd("R") data <- read.csv("DFT_glucose.csv", header = T, stringsAsFactors = F, fileEncoding = "SJIS") delta_data <- data |> pivot_wider(names_from...
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na.roughfix <- function(object, ...) UseMethod("na.roughfix") na.roughfix.data.frame <- function(object, ...) { isfac <- sapply(object, is.factor) isnum <- sapply(object, is.numeric) if (any(!(isfac | isnum))) stop("na.roughfix only works for numeric or factor") roughfix <- function(x) { if (any(...
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#' GO annotation data for human #' #' A data.frame containing GO annotation mappings for human genes. #' #' @format A data.frame with columns: #' \describe{ #' \item{GeneID}{Gene identifier} #' \item{GO}{GO term identifier} #' \item{Ontology}{GO ontology (BP, CC, MF)} #' } #' @source Generated from Bioconductor o...
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# Load required libraries # These libraries provide various functionalities such as UI components, data manipulation, # visualization, and mass spectrometry data processing. # This file is prefixed with underscore to ensure it loads first alphabetically library(shiny) library(shiny.semantic) # For semantic UI componen...
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R
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################################################################################ # Determines if a splice junction plot should be created. # # The event reactive that triggers creating a splice junction plot is based on # the Show plots button being clicked and Splice Junction Usage option being # chosen. The logic is ...
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R
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args <- commandArgs(TRUE) name <- args[1] set <- as.numeric(args[2]) nrep <- as.numeric(args[3]) combo1 <- eve::edd_combo_maker( la = c(0.6), mu = c(0.1), beta_n = c(-0.12, -0.10, -0.08, -0.06, -0.04, -0.02, 0), beta_phi = c(-0.04), age = c(10), model = "dsce2", metric = c("pd"), offset = c("simtime")...
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# Set directories DATA.DIR <- dirname(rstudioapi::getActiveDocumentContext()$path) setwd(DATA.DIR) # Load files for each genotyping chip library(dplyr) mega <- read.delim("MEGA_Chip.bim", header=F, quote="") neur <- read.delim("Neuro_Chip.bim", header=F, quote="") # Load call rate for all loci on each chip cr.mega <-...
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R
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library(pROC) data(aSAH) context("ci.formula") test_that("bootstrap cov works with smooth and !reuse.auc", { skip_slow() if (getRversion() > "3.6.0") { suppressWarnings(RNGkind(sample.kind = "Rounding")) } for (pair in list( list(ci, list()), list(ci.se, list(boot.n = 10)), list(ci.sp, list(b...
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if (!requireNamespace("here", quietly = TRUE)) install.packages("here") here::i_am("stats/lme_models/_setup.R") # anchor the repo root # Prefer sum-to-zero contrasts for ANOVA-style F tests options(contrasts = c("contr.sum", "contr.poly")) # Base packages used across scripts (+ the missing ones) pkgs <- c( "dplyr"...
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args <- commandArgs(TRUE) name <- as.character(args[1]) if (!dir.exists(name)) { dir.create(name) } setwd(name) if (!dir.exists("DDD_FREE_TES")) { dir.create("DDD_FREE_TES") } dir.create("DDD_FREE_TES") setwd("DDD_FREE_TES") dists <- list( list(distribution = "uniform", n = 1, min = 1.0, max = 1.5), list(...
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rm(list=ls(all=TRUE)) library(data.table);library(dplyr);library(stringr) source('/home/lorincn/isilon/Cheng-Noah/software/corefunctions/functions.R') ############################################################################## <GWAS filepath (w/ extension) here> <LD reference (w/o extension) here> savedir='/home/lor...
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#' miReact code dependencies #' @description This constitutes some of the core miReact code, which bayesReact depends on, obtained from https://github.com/muhligs/miReact (19/12/2023). #' For more information on miReact, please see their publication: https://doi.org/10.1038/s41598-021-88480-5 (Nielsen et al., Sci Rep, ...
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# In this script we will be gathering pathology diagnosis # terms to select NBL samples for downstream NBL subtyping # analysis and save the json file in nbl-subset folder # Detect the ".git" folder -- this will in the project root directory. # Use this as the root directory to ensure proper sourcing of functions no ...
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# paris_clustering.R # 1. load libraries & point reticulate at your conda env library(Seurat) library(igraph) library(reticulate) #Install scikit-network if needed reticulate::py_require("scikit-network") ###From Seurat object # 1. load your Seurat object or the adj matrix # (replace with your actual path) adj <- S...
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R
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--- title: "Lk single cell analysis" output: html_notebook --- run once for installation: ```{r} library(devtools) devtools::install_github(repo = "hhoeflin/hdf5r") devtools::install_github(repo = "mojaveazure/loomR", ref = "develop") devtools::install_github(repo = "aertslab/SCopeLoomR") ``` ```{r} library(lo...
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R
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ar1=function(n,rho=0.9) rho^toeplitz(0:(n-1)) tr=function(x) sum(diag(x)) anova_mugent=function(chisquares,LDlist,p) { # does NOT all LD matrices are the same across populations chisquares=c(chisquares) m=length(chisquares) R1=matrix(0,nr=m,nc=m) for(ll in 1:p) R1=R1+LDlist[[ll]]^2; R1=R1/p D=diag(sqrt(2*p)...
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#Purpose: Draw a density plot indicating minimizer density across a chromosome #Apply hard masking cutoff and see how it affects minimizer distribution #Assumes a file called "minimizers.txt" containing minimizer locations on a contguous sequence library(data.table) library(plyr) args <- commandArgs(trailingOnly = TR...
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R
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ar1=function(n,rho=0.9) rho^toeplitz(0:(n-1)) tr=function(x) sum(diag(x)) ## MuGenT mugent=function(Z,ldlist) { # can actually be general for multiple populations Z=as.matrix(Z) p=ncol(Z);m=nrow(Z);j=rep(1,p) stat=c(t(j)%*%(t(Z)%*%Z/m)%*%j) EZ=t(j)%*%diag(ncol(Z))%*%j # under H0 Kj=kronecker(t(j),t(j)) VZ...
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R
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createFolds <- function(z, k = 3) { s <- sample(1:k, length(z), replace = TRUE) aa <- sapply(1:k, function(x) which(s == x), simplify = FALSE) return(aa) } library(MASS) cross_glm <- function(inputData, k = 3, equation) { y <- inputData[, 1] x <- inputData[, -1, drop = FALSE] folds <- createFolds(y, ...
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createFolds <- function(z, k = 3) { s <- sample(1:k, length(z), replace = TRUE) aa <- sapply(1:k, function(x) which(s == x), simplify = FALSE) return(aa) } library(MASS) cross_glm <- function(inputData, k = 3, equation) { y <- inputData[, 1] x <- inputData[, -1, drop = FALSE] folds <- createFolds(y, ...
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R
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createFolds <- function(z, k = 3) { s <- sample(1:k, length(z), replace = TRUE) aa <- sapply(1:k, function(x) which(s == x), simplify = FALSE) return(aa) } library(MASS) cross_glm <- function(inputData, k = 3, equation) { y <- inputData[, 1] x <- inputData[, -1, drop = FALSE] folds <- createFolds(y, ...
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R
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createFolds <- function(z, k = 3) { s <- sample(1:k, length(z), replace = TRUE) aa <- sapply(1:k, function(x) which(s == x), simplify = FALSE) return(aa) } library(MASS) cross_glm <- function(inputData, k = 3, equation) { y <- inputData[, 1] x <- inputData[, -1, drop = FALSE] folds <- createFolds(y, ...
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R
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createFolds <- function(z, k = 3) { s <- sample(1:k, length(z), replace = TRUE) aa <- sapply(1:k, function(x) which(s == x), simplify = FALSE) return(aa) } library(MASS) cross_glm <- function(inputData, k = 3, equation) { y <- inputData[, 1] x <- inputData[, -1, drop = FALSE] folds <- createFolds(y, ...
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R
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createFolds <- function(z, k = 3) { s <- sample(1:k, length(z), replace = TRUE) aa <- sapply(1:k, function(x) which(s == x), simplify = FALSE) return(aa) } library(MASS) cross_glm <- function(inputData, k = 3, equation) { y <- inputData[, 1] x <- inputData[, -1, drop = FALSE] folds <- createFolds(y, ...
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R
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createFolds <- function(z, k = 3) { s <- sample(1:k, length(z), replace = TRUE) aa <- sapply(1:k, function(x) which(s == x), simplify = FALSE) return(aa) } library(MASS) cross_glm <- function(inputData, k = 3, equation) { y <- inputData[, 1] x <- inputData[, -1, drop = FALSE] folds <- createFolds(y, ...
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R
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# to perform lmm setwd("/Volumes/IqraMacFmri/visTac/fMRI_analysis/code/betaExtraction/stats_R") library(openxlsx) # import excel file library(reshape2) # reshape data library(ggplot2) # plots library(lmerTest) # linear mixed model library(emmeans) # multiple comparisons donnees <- read.xlsx("betaVal_sphereRoi_Tml_c...
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R
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43
createFolds <- function(z, k = 3) { s <- sample(1:k, length(z), replace = TRUE) aa <- sapply(1:k, function(x) which(s == x), simplify = FALSE) return(aa) } library(MASS) cross_glm <- function(inputData, k = 3, equation) { y <- inputData[, 1] x <- inputData[, -1, drop = FALSE] folds <- createFolds(y, ...
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R
1,233
43
createFolds <- function(z, k = 3) { s <- sample(1:k, length(z), replace = TRUE) aa <- sapply(1:k, function(x) which(s == x), simplify = FALSE) return(aa) } library(MASS) cross_glm <- function(inputData, k = 3, equation) { y <- inputData[, 1] x <- inputData[, -1, drop = FALSE] folds <- createFolds(y, ...
d0992a5b07cadc2673048819b4b3effbb6ffc490f85547753310abe581307baa
R
1,233
43
createFolds <- function(z, k = 3) { s <- sample(1:k, length(z), replace = TRUE) aa <- sapply(1:k, function(x) which(s == x), simplify = FALSE) return(aa) } library(MASS) cross_glm <- function(inputData, k = 3, equation) { y <- inputData[, 1] x <- inputData[, -1, drop = FALSE] folds <- createFolds(y, ...
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R
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createFolds <- function(z, k = 3) { s <- sample(1:k, length(z), replace = TRUE) aa <- sapply(1:k, function(x) which(s == x), simplify = FALSE) return(aa) } library(MASS) cross_glm <- function(inputData, k = 3, equation) { y <- inputData[, 1] x <- inputData[, -1, drop = FALSE] folds <- createFolds(y, ...
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R
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##-------------------------------------## ## COLOURS TAB ## ##-------------------------------------## tab_COLOURS <- tabItem( tabName = "Colours", textOutput(outputId = "session_id"), sidebarLayout( sidebarPanel(width = 4, selectInput(inputId = "...
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R
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#' Help function to check if suggested libraries are installed when required. #' #' @author Klev Diamanti #' #' @param x A character vector of R libraries. #' @param error Boolean to return error or a boolean (default). #' #' @return Boolean if the library is installed or not, and an error if #' `error = TRUE`. #' #' @...
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# Helper function to check whether Rslamdunk libraries are available # Install if libraries are not available # Copyright (c) 2015 Tobias Neumann, Philipp Rescheneder. # # This file is part of Slamdunk. # # Slamdunk is free software: you can redistribute it and/or modify # it under the terms of the GNU Affero General...
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varImpPlot <- function(x, sort=TRUE, n.var=min(30, nrow(x$importance)), type=NULL, class=NULL, scale=TRUE, main=deparse(substitute(x)), ...) { if (!inherits(x, "randomForest")) stop("This function only works for objects of class `randomFo...
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#' Load intensity data in R from tabix file #' #' A function to lead the snps data from the tabix indexed intensity file. #' #' @param cnv one line data.table in the usual cnv format #' @param samp one line samples file in the usual format #' @param snps the snps file for PennCNV, as data.table #' @param adjusted_lrr l...
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#' Monte Carlo Integration #' #' This internal function allows you to integrate over a half plane in the joint space of independent weighted chi-squares #' @param lam eigenvalues of positive-definite LD matrix #' @param niter number of Monte Carlo replicates used to approximate integral #' @param alpha type I error rat...
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## Example mutli-patient script library(LQT) ########### Set up config structure ########### pat_ids = paste0("Subject", 1:45) lesion_paths = list.files('/Users/JaneGoodall/Study/LesionMasks', full.names = TRUE) parcel_path = system.file("extdata","Schaefer_Yeo_Plus_Subcort", ...
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require("BiocParallel") # accept a input folder, a sample ID file, and a output folder # and a core number and then perform trimming for each file args = commandArgs(trailingOnly=TRUE) bash_script=args[1] input_folder=args[2] sample_ID=args[3] output_folder=args[4] core = as.numeric(args[5]) cat("script: ", bash_...
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#' @title Create Dockerfile #' @description Create a dockerfile to build a docker image #' @param path Path where to create Dockerfile #' @return Does not return anything. Writes a Dockerfile to current working directory or path specified. #' @author Roy Francis #' @importFrom readr write_file #' @export #' make_docker...
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library(lightgbm) # Load in the agaricus dataset data(agaricus.train, package = "lightgbm") data(agaricus.test, package = "lightgbm") dtrain <- lgb.Dataset(agaricus.train$data, label = agaricus.train$label) dtest <- lgb.Dataset.create.valid(dtrain, data = agaricus.test$data, label = agaricus.test$label) valids <- lis...
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# should be deflated for large p and small m # should be inflated for large m and small p alpha=0.05 at=function(alpha,meff,p) 1-(1-alpha^p)^meff at(alpha=0.05,meff=30,p=5) meff=1:100 ps=1:3 plot(meff,meff,type='n',ylim=c(0,1),xlab='effective number of independent SNPs',ylab='Type I error level',yaxt='n') axis(side=2,...
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--- title: "Seq QC table for manuscript" author: "Ryan Corbett" date: "2025" output: html_notebook: toc: TRUE toc_float: TRUE params: release: v15 --- This script adds the `rna-dna-qt-stats.tsv` data file as a supplemental table for the OpenPedCan manuscript. Load packages ```{r setup, include=FALSE} l...
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# Make up some data # True cell type proportions for 4 samples p_s1 <- c(0.5,0.3,0.2) p_s2 <- c(0.6,0.3,0.1) p_s3 <- c(0.3,0.4,0.3) p_s4 <- c(0.4,0.3,0.3) # Total numbers of cells per sample numcells <- c(1000,1500,900,1200) # Generate cell-level vector for sample info biorep <- rep(c("s1","s2","s3","s4"),numcells) ...
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context("Making plots") library(MOFA2) test_mofa2 <- load_model("test_mofa2.hdf5") # Data plots test_that("plot data overview works", { expect_silent(p <- plot_data_overview(test_mofa2)) }) test_that("plot data heatmap", { expect_silent(p <- plot_data_heatmap(test_mofa2, view = 1, factor = 1, silent = TRUE)) }) ...
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library(MOFA2) # An explicit pin is passed throughout so these keep passing when .mofapy2_version is bumped. test_that("matching and patch-level versions let training proceed", { expect_silent(.check_mofapy2_version("0.7.3", "0.7.3")) expect_message(.check_mofapy2_version("0.7.4", "0.7.3"), "patch release ahe...
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# The working directory is the directory that contains this test R file, if this # file is executed by testthat::test_dir # # testthat package is loaded, if this file is executed by testthat::test_dir context("tests/test_collapse_name_vec.R") # import_function is defined in tests/helper_import_function.R and tested in ...
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## code to prepare internal dataset goes here ## based on https://r-pkgs.org/data.html#sec-data-sysdata # Specifications for top matrix of Olink wide format data sets ---- olink_wide_spec <- dplyr::tibble( data_type = c( "NPX", "Ct", "Quantified" ), has_qc_data = c( TRUE, FALSE, TRUE )...
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#' Extract the CLR-transformed values from the ALDEX2 #' @description Microbiome data is compositional. When compositional data is examined using non-compositional methods, many problems arise. #' Performing a centered log-ratio transformation is a reasonable way to address these problems reasonably well. This particul...
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##-------------------------------------## ## NORM TAB ## ##-------------------------------------## tab_VAREXPLAINED <- tabItem( tabName = "Variance Explained", textOutput(outputId = "session_id"), br(),br(), tabsetPanel(type = "tabs", sidebarLayout( ...
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args <- commandArgs(TRUE) name <- as.character(args[1]) beta_n <- as.numeric(args[2]) batch <- as.numeric(args[3]) index <- as.character(args[4]) if (!dir.exists(name)) { dir.create(name) } # Get the current precise time current_time <- Sys.time() # Convert the current time to a numeric value time_numeric <- as.n...
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tr=function(x)sum(diag(x)) ar1=function(n,rho) rho^toeplitz(0:(n-1)) xvegas=function(z,R,Z_xqtls) { z=as.matrix(z);Z_xqtls=as.matrix(Z_xqtls) m=nrow(R);p=ncol(Z_xqtls) L=matrix(0,nrow=nrow(Z_xqtls),ncol=nrow(Z_xqtls)) for(i in 1:p) L=L+Z_xqtls[,i]%*%t(Z_xqtls[,i]) L=L/sqrt(m*p) mu=tr(R%*%R) variance=2*tr(...
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#' Help function checking if a variable is a vector of booleans. #' #' @inherit .check_params params author return #' #' @keywords internal #' @noRd #' check_is_boolean <- function(x, error = FALSE) { # check if input is a boolean vector if (!rlang::is_logical(x) || any(rlang::ar...
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R
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args <- commandArgs(TRUE) name <- as.character(args[1]) beta_phi <- as.numeric(args[2]) batch <- as.numeric(args[3]) index <- as.character(args[4]) if (!dir.exists(name)) { dir.create(name) } # Get the current precise time current_time <- Sys.time() # Convert the current time to a numeric value time_numeric <- as...
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#' @importFrom SeuratObject as.Seurat #' @export #' @note See \code{\link{as.Seurat.liger}} for scCustomize extension of this generic to converting Liger objects. #' #' SeuratObject::as.Seurat #' @importFrom SeuratObject WhichCells #' @export #' @note See \code{\link{WhichCells.liger}} for scCustomize extension of thi...
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##-------------------------------------## ##### REPORT ##### ##-------------------------------------## tab_REPORT <- tabItem( tabName = "Report", textOutput(outputId = "session_id"), tabsetPanel(type = "tabs", tabPanel("Report", sidebarLayout( ...
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# Behavioral GLMM specifications for Mano et al. (2026) # # Required packages: # install.packages(c("lme4", "lmerTest", "readr", "dplyr")) library(lme4) library(readr) library(dplyr) # USER SETTINGS data_file <- "path/to/behavior_for_analysis.csv" dat <- read_csv(data_file, show_col_types = FALSE) |> filter(condit...
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library(RCircos) if (!require("RCircos")) install.packages("RCircos") library(RCircos) getwd() setwd( "/data/nas1/liuyiding_OD/project/01_project_147/10_Circos") bio_markers <- data.frame( Chromosome = c("chr1", "chr2", "chr8", "chrX"), # 确保染色体格式正确 chromStart = c(1000000, 5000000, 11300000, 2000000), chromEnd = ...
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--- title: "chipseeker" output: html_document date: "2023-06-06" --- ```{r setup, include=FALSE} knitr::opts_chunk$set(echo = TRUE) ``` ```{r} library(ChIPseeker) library(TxDb.Mmusculus.UCSC.mm10.knownGene) library(rstudioapi) library(dplyr) ``` ```{r} #importing all files in the directory samplefiles <- list.files...
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##-------------------------------------## ## BEC TAB ## ##-------------------------------------## correct_be <- function(countMatrix, method, batch_label1, batch_label2, keep_biological, covariate){ if (method == "limma"){corrected_mat <- correct_limma(countMatrix, ...
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##-------------------------------------## ## COLOURS TAB ## ##-------------------------------------## make_show_color_plot <- function(df){ text <- df$colors print(text) ggplot(df, aes(x = group, y = add, fill = group, text = paste(colors))) + geom_point(size = 20, colo...
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# data ---- npx_df <- npx_data1 |> dplyr::filter( !grepl(pattern = "control", x = .data[["SampleID"]], ignore.case = TRUE) ) check_log <- check_npx(npx_df) # statistics ---- ttest_results <- olink_ttest( df = npx_df, check_log = check_log, variable = "Treatment", alternative = ...
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# pROC: Tools Receiver operating characteristic (ROC curves) with # (partial) area under the curve, confidence intervals and comparison. # Copyright (C) 2011-2014 Xavier Robin, Alexandre Hainard, Natacha Turck, # Natalia Tiberti, Frédérique Lisacek, Jean-Charles Sanchez # and Markus Müller # # This program is free soft...
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################################################################################ # Create an image of a gene expression plot. # # In order to stay inside the shinyapps.io memory limit this function reads the # data file, creates the plot as an image, and cleans everything up so that a # minimal amount of memory is used...
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#' Subset of liver cancer data from the Human Cancer Genome Atlas #' #' The test data contains fold-change ranked genes from the Human Cancer Genome Atlas (TCGA; n = 20), and matching motif counts and probabilities from human 3' UTR sequences. #' The data is generated from publicly available mRNA expression data and nu...
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#' Perform pairwise PERMANOVAs as a post-hoc #' @export #' pairwise_aitchison_PERMANOVA <- function (clr.samples, groups, relevant.comparisons, adjust.p = T, adj.method = "holm" ) { out_df <- data.frame() for (number in 1:nrow(relevant.comparisons)) { relevant.groups = groups[groups == relevant.comparisons[numb...
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--- title: "QC EFO MONDO Map file" output: html_notebook --- ## Load libraries ```{r load_libraries} suppressPackageStartupMessages({ library(tidyverse) }) ``` ## Read efo-mondo-map.tsv and histologies file ```{r read the two files} root_dir <- rprojroot::find_root(rprojroot::has_dir(".git")) integrate_dir <- fil...
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#.libPaths(c("E:/R_packages", .libPaths())) if (!requireNamespace("rstudioapi", quietly = TRUE)) { install.packages("rstudioapi") } library("rstudioapi") cur_dir = dirname(getSourceEditorContext()$path) extdata_source <- normalizePath(file.path(cur_dir, "..", "..", "..", "data", "lqt", "extdata"), ...
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data<-read.table("results_for_r_sess_paired_side.csv",header=TRUE,sep=",",dec=".") data$rat<-as.factor(data$rat) data$time<-as.factor(data$time) data$behavior<-as.factor(data$behavior) data$trial<-as.factor(data$trial_ID) data$sess<-as.factor(data$sess) data$recording<-as.factor(data$side) library(lme4) libra...
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rm(list=ls(all=TRUE)) library(mvnfast);library(mvnfast) source('simulations/mugent/functions.R') ################################################################################# niter=1000 ms=c(50,100,150) ps=c(2,5,7) rhos=c(0.9,0.1) RES=array(dim=c(length(ms),length(ps),length(rhos))) par(mfrow=c(6,3),mar=c(1.5,1.5,1...
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################################# Fig.1j #Read in the reduced_all R data file first DefaultAssay(reduced_all) <- "RNA" Lung_VNG <- subset(x = reduced_all, seurat_clusters == 6) nonLung_VNG <- subset(x = reduced_all, subset = Kcng1 == 0) gene_list <- read.csv(file = "Customized directory/Manuscript.Wei.et.al/Raw_Txt/D...
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# True cell type proportions for 4 samples p_s1 <- c(0.5,0.3,0.2) p_s2 <- c(0.6,0.3,0.1) p_s3 <- c(0.3,0.4,0.3) p_s4 <- c(0.4,0.3,0.3) # Total numbers of cells per sample numcells <- c(1000,1500,900,1200) # Generate cell-level vector for sample info biorep <- rep(c("s1","s2","s3","s4"),numcells) # Numbers of cells ...
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## ---- stats/learning_models/_setup.R ---- if (!requireNamespace("here", quietly = TRUE)) install.packages("here") here::i_am("stats/learning_models/_setup.R") # pins root to the repo that contains this file # 1) Packages (install on first run if missing) pkgs <- c( "rstan","brms","posterior","tidyverse","dplyr",...
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#'--- #' title: Calculate PSI values #' author: Christian Mertes #' wb: #' log: #' - snakemake: '`sm str(tmp_dir / "AS" / "{dataset}" / "02_PSIcalc.Rds")`' #' params: #' - setup: '`sm cfg.AS.getWorkdir() + "/config.R"`' #' - workingDir: '`sm cfg.getProcessedDataDir() + "/aberrant_splicing/datasets/"`' #' threa...
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library(raster) library(sf) library(rgeos) library(dplyr) library(tidyr) library(sp) # grid function from https://strimas.com/post/hexagonal-grids/ make_grid <- function(x, type, cell_width, cell_area, clip = FALSE) { if (!type %in% c("square", "hexagonal")) { stop("Type must be either 'square' or 'hexagonal'")...
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#' Cell type proportions from single cell PBMC data #' #' This dataset is from a paper published in PNAS that looked at differences in #' immune functioning between young and old, male and female samples: \ #' Huang Z. et al. (2021) Effects of sex and aging on the immune cell #' landscape as assessed by single-cell...
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rm(list=ls()) ## COMMON LIBRARIES AND FUNCTIONS source("100.common-variables.r") source("101.common-functions.r") source("300.variables.r") source("301.functions.r") ## SCRIPT SPECIFIC LIBRARIES ## ## library("doSNOW") library("foreach") ## loaded by doSNOW ## SCRIPT SPECIFIC FUNCTIONS ## SCRIPT CODE ## ## if( 1 ) ...
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library(readr) library(dplyr) library(stringr) library(openxlsx) ## set directories root_dir <- rprojroot::find_root(rprojroot::has_dir(".git")) analysis_dir <- file.path(root_dir, "analyses") output_dir <- file.path(root_dir, "tables", "results") output_file <- file.path(output_dir, "SuppTable2-Modules.xlsx") # 1. ...
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library(MOFA2) filepath <- system.file("extdata", "model.hdf5", package = "MOFA2") test_mofa2 <- load_model(filepath) # Data plots test_that("plot data overview works", { expect_silent(p <- plot_data_overview(test_mofa2)) }) test_that("plot data heatmap", { expect_silent(p <- plot_data_heatmap(test_mofa2, view = ...
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# Efficient training means training without giving up too much RAM # In the case of many trainings (like 100+ models), RAM will be eaten very quickly # Therefore, it is essential to know a strategy to deal with such issue # More results can be found here: https://github.com/lightgbm-org/LightGBM/issues/879#issuecommen...