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a9795c2b0e01f819421e29e2656e3c54e936524f07784730049541adc5572450
R
382
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#Load package suppressMessages(library(qvalue)) #Read command line arguments args <- commandArgs(trailingOnly = TRUE) try(if(length(args) != 1) stop("Incorrect number of arguments, usage> Rscript pi1.R INPUT")) opt_input = args[1]; #caucalate pi1 a<-read.table(opt_input) library(qvalue) pi0<-pi0est(a$V1,...
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R
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#### Notes #### #### Libraries #### library(matrixStats) #### Sourced functions #### #### Functions #### # Convert expression matrix to z-score matrix compute_zscore <- function(expr.matrix) { means <- rowMeans(expr.matrix, na.rm=TRUE) sds <- matrixStats::rowSds(expr.matrix, useNames=TRUE, na.rm=TRUE) zsco...
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R
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library(ggplot2) a <- 0.5 b <- 2 mDat <- do.call(rbind.data.frame, lapply(1:20, function(i) data.frame(postProb=sapply(0:i, function(j) (a+i-j) / (a+i+b)), coverage=i, notMod=0:i))) pdf('test_priors.pdf', width=8) ggplot(mDat) + geom_tile(aes(x=coverage, y=notMod, fill=postProb)) + theme_bw() + scale_fill_gr...
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R
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# This file is part of the standard setup for testthat. # It is recommended that you do not modify it. # # Where should you do additional test configuration? # Learn more about the roles of various files in: # * https://r-pkgs.org/testing-design.html#sec-tests-files-overview # * https://testthat.r-lib.org/articles/spec...
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R
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library(data.table) covar = fread("data/adc/adc_np.covar") pheno = fread("data/adc/adc_np_ord.txt", na.strings = "-1") covar = merge(covar, pheno[, .(IID, cerad)], "IID") covar = covar[!is.na(cerad)] covar[, cerad1 := ifelse(cerad == 1, 1, 0)] covar[, cerad2 := ifelse(cerad == 2, 1, 0)] covar[, cerad3 := ifelse(cerad...
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R
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# install_packages.R options(repos = c(CRAN = "https://cran.rstudio.com/")) # Function to install a package if it's not already installed install_if_missing <- function(package) { if (!require(package, character.only = TRUE)) { install.packages(package) } } # Install each package individually install.packages...
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R
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#=================================== # write text files of POLMM results #=================================== library(data.table) library(argparse) parser <- ArgumentParser() parser$add_argument("-r", "--rds", help = "results .Rds file") parser$add_argument("-o", "--out", help = "output file name") args <- parser$par...
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R
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library(data.table) library(ggplot2) gwas = readRDS("output/coloc/meta/caa_apoe/GWAS/gwas_rs7247551.Rds") cg13 = readRDS("output/coloc/meta/caa_apoe/ROSMAP/Brain_Prefrontal_Cortex_cg13119609_rs7247551.Rds") cg13_pdata = merge(gwas$dataset, cg13$dataset, by.x = "rsID", by.y = "snp") cg13_pdata[, ggplot(.SD, aes(-log10(...
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R
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#!../r # This should dynamically load stats cat("Is stats loaded?\n"); cat("search: ",search(),"\n"); if(!("package:stats" %in% search())){ cat("Nope!\n"); } cat("Calling ts(1:10)\n"); cat(ts(1:10),"\n"); cat("Now stats is loaded!\n"); cat("search: ",search(),"\n"); if(!("package:utils" %in% search())){ cat("N...
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R
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get_nodelabel_tips <- function(data_plot, node_label) { #' returns vector of tips descendants for a node label #' @param data_plot plot$data #' @param node_label the label of node, not node number #' Note: descendants_tips_from_node computed previously # get_nodelabel_tips(tp1$data, "N186") data_plot %>% ...
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R
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# restore_environment.R # Read the CSV file into a data frame package_info <- read.csv("R_environment.csv", stringsAsFactors = FALSE) # Install packages from the data frame for (row in 1:nrow(package_info)) { install.packages( package_info[row, "Package"], version = package_info[row, "Version"], depend...
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R
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library('NuPoP') nupop_input_dir <- '../nupop_input_temp/' # list all files in the input directory files <- list.files(nupop_input_dir, pattern = "*.seq") # for loop to run NuPoP on each file for (file in files) { file_ = paste0(nupop_input_dir,file) # run predNuPoP on each file predNuPoP(file_,species=1,mo...
272ee6c6db37f177e9459cae0a809d16793f248ab619d678742e8ba9e0c6b933
R
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setClass("ora_result", representation( gene = "character", database = "data.table", pAdjustMethod = "character", output = "data.table" ) ) setClass("userdata", representation( raw = "data.table", main = "data.table", rawidentifiers = ...
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R
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## Author: Jonathan Rosenblatt and Jason Stein ## Suggest default step size defaultStepSize <-function(list1, list2){ n1<- dim(list1)[1] n2<- dim(list2)[1] result <- ceiling(min(sqrt(c(n1,n2)))) return(result) } ### Testing: ## list.length <- 100 ## list.names <- paste('Gene',1:list.length, sep='') ## gene....
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R
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#source('AnalyseExperiment.R') source('AnalyseExperimentShort.R') knn = 10 folder<-'D:/CA1SR' resfolder<-paste(folder,'/Res/', sep="") dir.create(resfolder) dataname <-'Day1CA1SRPCF' pb<-read.csv(paste(folder,'/',dataname,'.csv',sep=""), col.names = c("x", "y", "z")) png(paste(resfolder,'/',dataname, '...
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R
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# ============================================================================ # This code prepares internal datasets # ============================================================================ # Dataset `fluNA` ------------------------------------------------------------ fluNA <- hyperSpec::flu fluNA[[2, ]] <- NA ...
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R
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#' Vectorized version of get_label_from_node function #' #' This function vectorizes the get_label_from_node function, allowing it to accept #' a vector of node numbers as input and return a vector of corresponding labels. #' #' @param node_number A vector of node numbers. #' #' @return A vector of node labels correspo...
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R
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## This script converts Rdata files to txt format library(GenomicRanges) inputDir="/data/clusterfs/lag/users/gokala/beat-dyslexiaevol/results/gSEM/" for (i in list.files(inputDir, pattern="multivarGWAS_dys_rhyimp_v2.RData", all.files=F, full.names=F)) { tmp_dir=gsub(" ","", paste(inputDir,i), fixed=T) print(...
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R
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compsplit <- function(x, split) { if (split %in% gs("special.characters")) split <- paste0("\\", split) res <- strsplit(x, split) if (is.list(res)) { withspace <- any(unlist(lapply(res, grepl, pattern = "^\\s+|\\s+$"))) res <- lapply(res, gsub, pattern = "^\\s+|\\s+$", replacement = "") } els...
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R
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# # (1) Make R packages available # library("devtools") library("roxygen2") # # (2) Create documentation file(s) # document() # # (3) Build R package and PDF file with help pages # build(args = "--compact-vignettes=both") build_manual() # # (4) Install R package # install(build_vignettes = TRUE) # # (5) Che...
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R
480
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#' mochims__fraction_bound #' #' Calculate fraction bound in 3-state model. #' #' @param folding_energy folding energies for 3-state model (required) #' @param binding_energy binding energies for 3-state model (required) #' @param RT constant (default:0.001987*(273+24)) #' #' @return Fraction bound #' @export mochims_...
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R
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#------------------------------------------------ # list of ROSMAP IDs with age of death available #------------------------------------------------ library(data.table) library(readxl) rosmap <- as.data.table(read_excel( "/data_global/ROSMAP/greg_20200109/dataset_843_basic_01-09-2020.xlsx")) rosmap <- rosmap[!(...
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R
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#!/usr/bin/env Rscript args <- (commandArgs(TRUE)) cov <- read.table(args[1]) c_min <- min(cov$V2) c_max <- max(cov$V2) c_max <- c_max+floor((c_max/10)) jpeg(file="insert.jpg", height=400, width=1300, pointsize = 25) par(mar=c(4,4,1,1)) plot(cov$V1,cov$V2,type="l",col="blue",xlab="",ylab="",ylim=c(c_min,c_max),bt...
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R
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kenwardroger <- function(w.random) { # # Kenward-Roger method for meta-analysis # (Partlett & Riley, 2017, Stat Med) # w1p <- sum(w.random) w2p <- sum(w.random^2) w3p <- sum(w.random^3) # IE <- w2p * 0.5 - w3p / w1p + 0.5 * (w2p / w1p)^2 var <- (1 + 2 * (w3p / w1p - (w2p / w1p)^2) / IE) / w1p df <...
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R
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# Interpolation functions spd.interpolate.euclidean <- function(x, y, t, ...){ return((1-t)*x + t*y) } spd.interpolate.logeuclidean <- function(x, y, t, ...){ return(expm2((1-t)*logm2(x) + t*logm2(y))) } spd.interpolate.riemannian <- function(x, y, t, ...){ yt <- spd.logmap(y, p = x) return(spd.expma...
94dbe685913ea3eaf8eb65d64d5977011139705657cc22bd9acc3a8ad880aac9
R
494
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#' FMRI BOLD data #' #' Dataset contains fMRI BOLD data from from five subjects in each of five #' resting-state conditions. Object is a data frame with the following fields: #' \itemize{ #' \item{"Subject"} Subject ID #' \item{"Condition"} Condition label #' \item{"Data"} A 150 x 5 matrix containing the standard...
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R
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# load libraries install.packages("psych") install.packages("tidyverse") install.packages("dplyr") install.packages("Rcmdr") install.packages("reshape2") install.packages("viridis") install.packages("hrbrthemes") install.packages("ggpmisc") install.packages("cowplot") install.packages("ggpubr") install.packages("lavaan...
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R
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#!/usr/bin/env Rscript library(caret) library(waveslim) library(gtools) args <- commandArgs(trailingOnly = TRUE) outdir <- args[1] observations <- as.integer(args[2]) Level=1 for (i in 0:(observations-1)) { M <- read.csv(paste0(outdir,"/VCF/output_",i,".csv"), header = TRUE, row.names = NULL) wS<-dwt.2d(as...
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R
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#=========================================== # create list of duplicate IIDs to remove #=========================================== pacman::p_load(data.table, magrittr, stringi) psam <- fread("tmp/adc_no_naccid_dups.psam") naccids <- psam[, `#IID` := stri_replace_first_regex(`#IID`, ".*_", "")] na...
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R
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library(tidyverse) df <- read.csv('/data/project//ukb_reliability_in_prediction/text_files/increase_rel_HGS.csv') plt <- ggplot(df, aes(Reliability,test_R2,colour=Beh)) + geom_point() + geom_line() + geom_text(aes(label = Time_point), colour = 'black', nudge_y = -0.002, nudge_x = 0.004) + theme_classic() + ...
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R
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#' Paracetamol spectrum #' #' A Raman spectrum of a paracetamol tablet. #' #' @name paracetamol #' @docType data #' @format The spectrum was acquired with a Renishaw InVia spectrometer from #' 100 to 3200 cm^-1 in step scan mode. Thus the spectrum has several #' overlapping wavelength regions. #' @author C. Beleite...
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R
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library(SCopeLoomR) library(xlsx) #Read counts data from loom file loom_path <- file.path('s_fca_biohub_head_10x.loom') loom <- open_loom(loom_path, mode="r+") dgem <- get_dgem(loom) close_loom(loom) #filter Lk and CrzR coexpressed cell and process cell <- dgem[,which(dgem['Lk',]!=0 & dgem['CrzR',]!=0)] ce...
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R
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#!/usr/bin/env Rscript args <- (commandArgs(TRUE)) ent <- read.table(args[1]) len <- max(ent$V1) jpeg(file="entropy.jpg", height=400, width=1300, pointsize = 25) par(mar=c(4,4,1,0)) plot(ent$V1,ent$V2, type="l",col="red",xaxt="n",yaxt="n",xlab="",ylab="",ylim=c(0,2),bty="n",lwd=1, main="Entropy of the reads") axis...
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R
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source('./scripts/01_Setup.R') datax <- read.table("./data/processed/txt/MSA_PANTHER_BP_GOslim.txt", sep = "\t", header=T, skip=11, quote = "", stringsAsFactors = FALSE) datax2= datax[,c(1,7)] delimiters = "\\(G" aa2= strsplit(datax2[,1], delimiters, perl = TRUE) aa3= sapply(aa2, f...
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R
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#' get_node_from_label #' #' Helper function for tree manipulation: get the node number from a node label. #' #' @param tree A phylo object with node labels. #' @param node_label The node label from which we want to return the node number. #' #' @return The node number corresponding to the given node label. #' @require...
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R
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addvars2long <- function(x) { levs <- NULL fac <- is.factor(x$var1) | is.factor(x$var2) # if (!(is.numeric(x$var1) & is.numeric(x$var2))) { levs <- unique(c(x$var1, x$var2)) x$var1 <- as.numeric(factor(x$var1, levels = levs)) x$var2 <- as.numeric(factor(x$var2, levels = levs)) } # res <- t...
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R
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#================================= # fix NACC IIDs #================================= pacman::p_load(data.table, magrittr, stringi) fam <- fread("data/plink/adc_original_iid.fam") fam[, V2 := stri_replace_first_regex(V2, "[:alnum:]*_", "")] fam[, V2 := stri_replace_first_regex(V2, "[:alnum:]*:", "")] fam[, V2 := stri...
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R
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#!/usr/bin/env Rscript args <- (commandArgs(TRUE)) map <- read.table(args[1]) map_max <- max(map$V2) map_max=map_max + (map_max/10) mapped=head(map$V2,1); unmapped=tail(head(map$V2,2),1) map_per=round((mapped/(mapped+unmapped))*100) unmap_per=round((unmapped/(mapped+unmapped))*100) jpeg(file="map.jpg", height=300, ...
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R
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# merge phenotype files for NACC, ROSMAP, and ACT library(data.table) nacc_ord = fread("shared/adc_np_ord.txt", na.strings = "-1") nacc_bin = fread("shared/adc_np_bin.txt", na.strings = "-1") rosmap = fread("shared/rosmap_np.pheno", na.strings = "-1") act = fread("data/act/act_np.pheno", na.strings = "-1") # merge na...
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# color identification -------------------------------------------------------- # ColorForGroup <- function(){ # obtain the color representations of two group of subjects isfahan <- MetBrewer::met.brewer("Isfahan1") length(isfahan) isfahan[1] hc_color <- colorspace::lighten(isfahan[2], 0.35) mdd...
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R
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#=========================================== # create list of duplicate IIDs to remove #=========================================== pacman::p_load(data.table, magrittr, stringi) psam <- fread("tmp/adc_no_dup.psam", check.names = T) psam[, IID := stri_replace_first_regex(X.IID, "[[:digit:]]*_", "")] psam[, IID := str...
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R
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# Load data to be used inside package human_tfs <- read.csv("datasets/humanTFs.txt", header = FALSE)[, 1] human_tfs_v2 <- read.csv("datasets/humanTFs_v2.txt", header = FALSE)[, 1] human_tfs_v3 <- read.csv("datasets/humanTFs_v3.txt", header = FALSE)[, 1] human_kinases <- read.csv("datasets/humanKinases.txt", header = F...
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R
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# To manage the packages # library(renv) # renv.log should be able to reproduce the whole environment # R packages on CRAN library(tidyverse) library(rlist) library(xlsx) library(glue) #library(ggplot2) loaded with tidyverse library(ggnewscale) library(scales) library(qualpalr) library(RColorBrewer) library(ggplotif...
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library(Seurat) library(dplyr) library(SeuratDisk) args<-commandArgs(T) scrna_path = args[1] spatial_path = args[2] celltype_final = args[3] output_path = args[4] sc_rna <- LoadH5Seurat(scrna_path) sc_rna <- SCTransform(sc_rna) spatial <- LoadH5Seurat(spatial_path) spatial <- SCTransform(spatial) anchors <- FindTrans...
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R
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test_that("constant genes are discarded correctly", { expression <- rbind( rep.int(1, 100), matrix(rnorm(500), nrow = 5), rep.int(0.5, 100), rnorm(100) ) genesymbols <- c("T1", "T2", "T3", "T4", "T5", "T6", "R1", "R2") is_regulator <- c(0, 0, 0, 0, 0, 0, 1, 1) fit <- scregclust( expressi...
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R
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#' @name extract_earliest_crop #' @title Extract earliest date for a crop by province #' #' @description `extract_earliest_crop()` extracts the sample with the earliest date for a crop by province. #' #' @param database A data.frame containing the crop database. #' @return A tibble that contains the earliest date for e...
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R
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library(gplots) x=read.delim(gzfile("57epigenomes.RPKM.pc.gz"), row.names=1) x$E000=NULL names=read.delim("EG.name.txt",F) colnames(x)=paste(colnames(x), gsub("_", " ", as.character(unlist(sapply(colnames(x), function(x) names[names$V1==x, "V2"]))))) y=as.matrix(cor(x, method='spearman')) colnames(y)=colnames...
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R
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#' get_label_from_node #' Helper for tree manipulation: get the node label from a given node number. #' #' @param tree A phylo object with node labels. #' @param node_number The node number for which to retrieve the label. #' #' @return The label of the specified node. #' #' @examples #' tree <- read.tree("tree.nwk") #...
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R
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source('./scripts/01_Setup.R') datax <- read.table("./data/processed/txt/Control_PANTHER_BP_GOslim.txt", sep = "\t", header=T, skip=11, quote = "", stringsAsFactors = FALSE) head(datax) dim(datax) # 83 7 datax2= datax[,c(1,7)] head(datax2) delimiters = "\\(G" aa2= strsplit(datax2[,1], delimiters, perl = TR...
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R
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#' Quinine fluorescence spectra #' #' Fluorescence spectra of different dilutions of quinine forming a #' calibration set. #' #' See the vignette: `vignette("flu", package = "hyperSpec")` #' #' @name flu #' @docType data #' @format The data set has 6 fluorescence emission spectra measured on #' quinine concentrations...
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R
600
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#------------------------- # Check heterozygosty #------------------------- library(data.table) het <- fread("tmp/rosmap_1c.het") # (total number genotypes - number homozygous) / total number genotypes het[, het.rate := (`N(NM)` - `O(HOM)`) / `N(NM)`] # 3SD threshold for failure het.fail <- het[het.rate < mean(het....
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R
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pkgs <- installed.packages() vers <- pkgs[, "Version"] data.frame(names(vers),vers) # To cite the R package 'cluster' in publications use: citation("readxl") citation('org.Hs.eg.db') citation('data.table') citation('scales') citation('DNAcopy') citation('RColorBrewer') citation('DNAcopy')...
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R
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--- #title: "Workflow in R package meta" #author: "Guido Schwarzer" output: rmarkdown::pdf_document: number_sections: true rmarkdown::html_vignette: toc: false number_sections: true vignette: > %\VignetteIndexEntry{meta: General Package for Meta-Analysis - Workflow} %\VignetteEngine{knitr::rmarkdown} ...
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logm2 <- function(x){ #lx <- logm(x) e <- eigen(x) lx <- e$vectors %*% diag(log(e$values)) %*% t(e$vectors) return((lx + t(lx))/2) } expm2 <- function(x){ #ex <- expm(x) e <- eigen(x) ex <- e$vectors %*% diag(exp(e$values)) %*% t(e$vectors) return((ex + t(ex))/2) } sqrtm2 <- function...
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# packages library(tidyverse) library(data.table) library(patchwork) library(magrittr) library(ggrepel) # visualization theme_set( theme_classic() + theme(strip.background = element_rect(color = NA) ) ) # inverse PCA inv_pca <- function(dat, pca){ .rot <- pca$rotation .scale <- pca$scale .mean <-...
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#' get_descendants_from_node #' Helper function for tree manipulation. #' Get the labels of both tips and nodes descendants from #' a given node number in a phylogenetic tree. #' #' @param tree A phylogenetic tree object. #' @param node_number The node number from which to retrieve the descendants. #' @return A vect...
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library(ggplot2) library(plyr) d<-read.csv("boxplot_gamma.csv", header = TRUE, sep = ",", dec = ".") attach(d) names(d) mydata <- within(data.frame(x=Groupe), { y<-Median.Gamma}) ## Dot plot over boxplot gp = ggplot(mydata, aes(x, y, col =x)) + geom_boxplot(outlier.size=0, outlier.stroke=0) + labs(title= "Di...
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#=========================================== # create list of duplicate IIDs to remove #=========================================== pacman::p_load(data.table, magrittr, stringi) psam <- fread("tmp/adc_no_naccid_dups.psam") naccids <- psam[, `#IID` := stri_replace_first_regex(`#IID`, ".*_", "")] na...
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#' mochims__format_dir #' #' Plot fitness versus growth rate. #' #' @param dir_suffix directory suffix (required) #' @param stagenum stage number (required) #' @param base_dir base directory (required) #' @param no_digits number of digits to use for stage number #' #' @return Absolute directory character string #' @ex...
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source('./scripts/01_Setup.R') datax <- read.table("./data/processed/txt/MSA_PANTHER_CC_GOslim.txt", sep = "\t", header=T, skip=11, quote = "", stringsAsFactors = FALSE) datax2= datax[,c(1,7)] aa= grep('Unclassified', datax2[,1],value = T) datax2= datax2[!datax2[,1]%in%aa,] delimiters = "\\(G" aa2= strsplit(da...
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# Plots FreeSurfer-labeled brain regions that were related to chronic inflammation estimates using the ggseg package. # For questions: theodore_turesky@gse.harvard.edu library(ggseg) # Subcortical someData = data.frame( region = c("putamen"), p = c(1), stringsAsFactors = FALSE); #someData$hemi = "left" ggseg(...
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setwd() set.seed(42) library(dplyr) # import raw raw_counts_mat = read.delim("../99.processed/counts_mat.txt", sep = '\t', check.names = F) # cleaning counts_mat = as.matrix(counts_mat) # extract metadata meta = data.frame(orig.ident = colnames(counts_mat), stringsAsFactors = F) meta$CellLine = gsub("MgEtOH", "", m...
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#### Markos et al #### Conversion of integrated SingleCellExperiment object to h5ad for analysis with python #### Can be run from bash e.g. by `Rscript 02_Convert_to_anndata.R` # uncomment and set working directory to repository path if run within RStudio: # setwd('path/to/downloaded/repository') # Convert integrated...
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#! /usr/bin/Rscript --vanilla #------------------------- # Check heterozygosty #------------------------- library(data.table) het <- fread("tmp/adc_qc1_het.tmp.het") # (total number genotypes - number homozygous) / total number genotypes het[, het.rate := (`OBS_CT` - `O(HOM)`) / `OBS_CT`] # 3SD threshold for failu...
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library(data.table) library(magrittr) library(POLMM) bfile <- "tmp/mega_np_prune" n_parts_grm <- 14 chrs <- 1:22 tmp_dir <- "tmp/" for (chr in chrs) { for (part in 1:n_parts_grm) { getSparseGRMParallel(chr, part, n_parts_grm, bfile, tempDir = tmp_dir, threadNum ...
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context("spd-mean") # Positive definite matrixTesting data x <- lapply(1:10, function(i) cov(matrix(rnorm(100), ncol = 5))) test_that("All mean methods run without error", { expect_error(spd.mean(x, method = 'euclidean'), NA) expect_error(spd.mean(x, method = 'logeuclidean'), NA) expect_error(spd.mean(x,...
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data <- read.csv('data/axis_expression_data.csv') data <- ddply(data, c('Mot', 'Hem', 'Axis'), summarize, 'r' = cor(LearningRate, AxisIncrease)) data$id <- paste(data$Hem, data$Mot) data$id <- factor(data$id, c('LH SomMotB', 'LH SomMotA', 'RH SomMotA', 'RH SomMotB')) data$Axis <- factor(data$Axis, c('Exp...
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context("spd-dist") # Positive definite matrix Testing data x <- cov(matrix(rnorm(100), ncol = 5)) y <- cov(matrix(rnorm(100), ncol = 5)) test_that("All distance methods run without error", { expect_error(spd.dist(x, y, method = 'euclidean'), NA) expect_error(spd.dist(x, y, method = 'logeuclidean'), NA) ...
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# File: metric_funs.R # Author: Kelly Chang # Date: Oct 2017 # Version: 1.0 # # Description: Helper R functions to find various points in a trace. # find_dxdtMax<-function(t, x){ dxdt<-diff(x) / diff(t) i_max<-which.max(dxdt)[1] t_max<-t[i_max] up_max<-dxdt[i_max] list(...
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# prep SAIGE results for METAL meta-analysis library(data.table) library(argparse) source("code/functions/strip_alleles.R") source("code/functions/make_or_95_ci.R") parser = ArgumentParser() parser$add_argument("-r", "--results") parser$add_argument("--rm_alleles_rsid", default = "FALSE") parser$add_argument("-o", "-...
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rm(list=ls(all=TRUE)) #path where all folds results are stored + beginning of filename path='/Users/jheitz/git/dslab/new_data/val_predictions/20181110_14-15-08_new_data3__fold' data=data.frame() for (fold in 0:9){ data=rbind(data,read.csv(paste(path,fold,'.csv',sep=""))) } data$error=abs(data$label-data$prediction) ...
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source('./scripts/01_Setup.R') datax <- read.table("./data/processed/txt/MSA_PANTHER_MF_GOslim.txt", sep = "\t", header=T, skip=11, quote = "", stringsAsFactors = FALSE) datax2= datax[,c(1,7)] aa= grep('Unclassified', datax2$PANTHER.GO.Slim.Molecular.Function,value = T) datax2= datax2[!datax2$PANTHER.GO.Slim.Molecular...
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## Adapted from https://gist.github.com/slowkow/ c6ab0348747f86e2748b#file-counts_to_tpm-r-L44 tpm <- function(counts, lengths) { rate <- counts / lengths rate / sum(rate) * 1e6 } ## ## read table from featureCounts output args <- commandArgs(T) tag <- tools::file_path_sans_ext(args[1]) ftr.cnt <- read.tabl...
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# Mean functions spd.mean.euclidean <- function(x, ...){ Reduce(`+`, x)/length(x) } spd.mean.logeuclidean <- function(x, ...){ expm2(Reduce(`+`, lapply(x, logm2))/length(x)) } spd.mean.riemannian <- function(x, p = 0, tol = .01, max.iter = 50){ if (p < -1 | p > 1){ stop('p must lie in the interva...
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source('./scripts/01_Setup.R') datax <- read.table("./data/processed/txt/Control_PANTHER_CC_GOslim.txt", sep = "\t", header=T, skip=11, quote = "", stringsAsFactors = FALSE) head(datax) dim(datax) # 20 7 datax2= datax[,c(1,7)] head(datax2) aa= grep('Unclassified', datax2[,1],value = T) datax2= datax2[!datax2[,1]%i...
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#' break character strings into words #' #' @description Separates a character string into individual words. Wraps stringr package str_split. #' @usage tokenize(x) #' @param x length 1 character vector #' @return words character vector of tokenized words #' @seealso \code{\link{str_split}} \code{\link{boundary}} #' @ex...
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options(stringsAsFactors = FALSE) list.of.packages <- c("dplyr") new.packages <- list.of.packages[!(list.of.packages %in% installed.packages()[,"Package"])] if(length(new.packages)) install.packages(new.packages) library(dplyr) argv <- commandArgs(TRUE) all.1000genomes = read.table(paste(argv[1], "/ALL.1000genemes....
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#----------------------------------- # creates list of IDs +-3SD of mean # heterozygosity in PLINK .het file #----------------------------------- library(data.table) cargs <- commandArgs(trailingOnly = TRUE) het <- fread(cargs[1]) # (total number genotypes - number homozygous) / total number genotypes het[, het.rate...
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# Edit `one_over_f` function from `primer` package to control variance (Stevens, 2009). # Original function is available on [GitHub](https://github.com/HankStevens/primer). # Copyright Hank Stevens. one_over_f <- function(gamma = 1, N = 200, outvar = 1){ N.2 <- N/2 sine.waves <- matrix(NA, nrow = N, ncol = N.2) ...
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# TODO Find a way to make it functional ! with a geom #' modifies in place the plot data to be able to plot geom_facet directly #' without creating intermediate datasets #' @param data the plot data #' @param nested_col The name of the column containing the nested variable. #' @param var The name of the nested varia...
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#' @importFrom geigen geigen # Distance functions spd.dist.euclidean <- function(x,y,...){ norm(x - y, type = 'F') } spd.dist.logeuclidean <- function(x,y,...){ norm(logm2(x) - logm2(y), type = 'F') } spd.dist.cholesky <- function(x,y){ norm(chol(x) - chol(y), type = 'F') } spd.dist.riemannian <- funct...
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spd.transport.pt <- function(x, from, to, nsteps) { # Generate discrete geodesic from source to target geod <- lapply(seq(0, 1, length.out = nsteps+1)[-1], function(i) { spd.interpolate(from, to, t = i, method = 'riemannian') }) # Iterate over rungs trans <- spd.expmap(x, from) source ...
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source('./scripts/01_Setup.R') Pico <- readRDS("./results/article_figures/Pico_Segment_Median.rds") PTA <- readRDS("./results/article_figures/PTA_Segment_Median.rds") aahist2= ggarrange(Pico, PTA, labels = c('A','B')) ggsave(aahist2, filename = './results/PTA_Pico_segmentvalue.png', unit = 'cm', width = 20, h...
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#' Projection onto the tangent space #' #' Function projects an SPD matrix x onto the tangent space at a point p #' #' @param x A symmetric positive definite matrix #' @param p The point on whose tangent space to project x #' @return A symmetric matrix. #' @export spd.logmap <- function(x, p = NULL){ if (!'spd.ma...
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#' Ensure that the spectra matrix has the wavelengths in column names #' #' @param spc `hyperSpec` object. #' #' @return `hyperSpec` object with wavelengths in column names of `$spc`. #' #' @concept manipulation #' #' @export #' .spc_fix_colnames <- function(spc) { colnames(spc@data$spc) <- signif(spc@wavelength, dig...
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#' Readjust the pannels from the ggtree plot and reexport as ggplot object #' #' @param plot_object a ggtree plot object panneled #' @param width_mult a vector of values to multiply the original width of each panel. #' Note that the tree counts as a pannel. grop_redraw <- function(plot_object, width_mult = c(1, ....
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lava_results = read.table("/data/workspaces/lag/workspaces/lg-genlang/Working/23andMe/Dyslexia2/Evolution/dys_rhy_pleiotropy/results/LAVA/D-RI_vs_wmTract_fromYasmina.txt", header = T, sep = "\t") ########################################################## # FDR # remove duplicate rows (if ther...
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#' @name extract_GDD #' @title Extract growing degree days #' #' @description `extract_GDD()` extracts growing degree days from a user provided GDD raster dataset at site locations. #' #' @param sites A data.frame with an ID and sfc_Point geometry containing site locations. #' @param gdd_raster A raster containing grow...
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#' counts the frequency of unique tokens #' #' @description Call word tokenizer, then count the frequency of each unique word. #' @usage count_tokens(x) #' @param x length 1 character vector #' @return A table of word frequencies #' @seealso \code{\link{str_split}} \code{\link{boundary}} \code{\link{tokenize}} #' @exam...
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library(GenomicRanges) # Get HAR SNC Overlap Information SNC_df = read.delim('../../SNC_MAGGIE/SNCs_hg38_995-matched.txt', sep='\t') SNC_df = SNC_df[, c('hg38_chr', 'hg38_start', 'hg38_end', 'hg38_name', 'hg38_Ref', 'Anc')] colnames(SNC_df) = c('chr', 'start', 'end', 'Name', 'Ref', 'Anc') SNCs = GRanges(SNC_df) length...
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library(reticulate) use_virtualenv("causal") # Define the Python function in R py_run_string(" import pandas as pd import dodiscover as dod def kernelcdtest(Y, T, X, R=1000, ncores=1): df_dict = {'Group': [int(ti) for ti in T]} yvars = [] for i in range(0, Y.shape[1]): yvar = 'Y{:d}'.format(i) ...
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--- title: "ChiSquareTest" output: pdf_document --- ```{r setup, include=FALSE} knitr::opts_chunk$set(echo = TRUE) ``` ## R Markdown ```{r} install.packages("readxl") ``` ```{r} #install.packages("dplyr") #install.packages("tidyr") #install.packages("knitr") ``` ```{r} library(dplyr) library(tidyr) ``` ```{r} l...
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#=================================================== # merge .pheno and .covar files for SAIGE analysis #=================================================== library(data.table) library(argparse) parser <- ArgumentParser() parser$add_argument("--pheno", "-p", help = "phenotype file") parser$add_argument("--covar", "-c...
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library(lme4) library(sjPlot) library(performance) library(ggplot2) library(lmerTest) library(multcomp) library(effects) library(jtools) library(lsmeans) library(interactions) library(emmeans) library(car) ############## MODELLING ##################################################### df = read.csv("dat...
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args <- commandArgs(trailingOnly = T) filenamex=as.character(args[[1]]) options(scipen=999) outpath= "./data/processed/preseq" source('./scripts/01_Setup.R') if (file.exists(file.path(outpath, filenamex))) { setwd(file.path(outpath, filenamex)) samples= list.files() xx=c() for (i in 1:length(samples)){ # print(i) ...
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#' get_tips_descendants_from_node #' Helper function for tree manipulation. #' Get the labels of tips (not nodes) descendants from a given node number in a tree. #' #' @param tree The input tree object. #' @param node_number The number of the node from which to retrieve the tips descendants. #' @return A character vect...
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#' Projection from the tangent space #' #' Function projects a tangent vector x (a symmetric matrix) at a point p #' onto the space of SPD matrices. #' #' @param x A symmetric matrix #' @param p The point to whose tangent space x belongs #' @return A symmetric, positive-definite matrix. #' @export spd.expmap <- functi...
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source('./scripts/01_Setup.R') setwd("./data/processed/rds") aa= grep("MAD",list.files(), val=T) aa2= grep('500kb.rds', aa, val=T) aa2=aa2[!(aa2%in%c("MAD_500kb.rds","MAD_ConfScore_500kb.rds"))] for (i in 1:length(aa2)){ fname = file.path('./data/processed/rds/',aa2[i]) readRDS(fname)} all = lapply(aa2...
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#' Mark peak #' #' Marks location of the *first* spectrum at the data point closest to the #' specified position on the current plot. #' #' @param spc the `hyperSpec` object #' @param xpos position of the peak(s) in current x-axis units #' @param col color of the markers and text #' #' #' @author R. Kiselev #' #' @conc...
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context("spd-transport") # Positive definite matrixTesting data from <- cov(matrix(rnorm(300), ncol = 3)) to <- cov(matrix(rnorm(300), ncol = 3)) x <- .8 * from + .2 * cov(matrix(rnorm(300), ncol = 3)) x <- spd.logmap(x, p = from) y1.pt <- spd.transport(x, from = from, to = to, method = 'pt', nsteps = 10) y...