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#' Baujat plot to explore heterogeneity in meta-analysis #' #' @description #' Draw a Baujat plot to explore heterogeneity in meta-analysis. #' #' @aliases baujat baujat.meta #' #' @param x An object of class \code{meta}. #' @param yscale Scaling factor for values on y-axis. #' @param xlim The x limits (min,max) of ...
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####Heatmap creation #### Coded: Benjamin Saef #### Date as of commenting and documentation - 05/28/2024 load("/FNIH_Project_2/Current_Analysis_data.rdata") library(Hmisc) library(reshape2) out_project <- "/FNIH_Project_2/Paper1/Spearman_Analysis" #Folder where you want all output written to, a results and plot folde...
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## Run it with R version 4.0.3 and biomaRt v2.45.9. ## Otherwise the getBM function does not work. ## Run gene-ontology enrichments on variants within ## HGEs that also impact brain structure ## mapping to genes using PsychENCODE eQTL options(stringsAsFactors=FALSE) library(GenomicRanges) library(biomaRt) #library(An...
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###################### ANALYSES CODE STARTS HERE ######################### require( geomorph ) require( ape ) require( geiger ) require( abind ) require( RColorBrewer ) require( cluster ) require( matlib ) require( ggtree ) require( rlang ) require( cowplot ) require( tidytree ) require( dplyr ) require( g...
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#!/usr/bin/Rscript # Clear workspace rm(list = ls()) # Load libraries if(!require(NBR)) install.packages("NBR"); library(NBR) source("https://raw.githubusercontent.com/zchuri/BilingualBrainNet/main/Code/AuxFunctions/valid_url.R") # Read phenotypic data info <- read.csv("https://raw.githubusercontent.com/zchuri/Bilin...
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###Script 22 #Syngo analysis library(readxl) library(dplyr) library(ComplexHeatmap) library(RColorBrewer) library(viridis) #Get de genes de.res <- read.csv("output/DE_plots/Cleaned_MAST_neuronal_all_genes.csv") %>% filter(FDR < 0.1) cell_sets <- c("2.L6.CT.CTX.Glut", "16.L6.CT.CTX.Glut", "37.L6b.CTX.Glut...
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#' phenoscanner #' #' phenoscanner queries the PhenoScanner database of genotype-phenotype associations from inside R. #' @param snpquery a vector of SNPs. #' @param regionquery a vector of genomic regions. #' @param genequery a vector of gene names. #' @param catalogue the catalogue to be searched (options: None, GWAS...
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#Use system.file("extdata", "2010.csv", package = "testdat", mustWork = TRUE) #' Title #' #' @param genes #' #' @return #' @export #' #' @examples fromAny2Ensembl = function(genes){ if(substr(genes[1],1,1) == "X"){ return(fromGeneName2Ensembl(fromXtIDToGeneSymbols19K(genes))) }else if(substr(genes[1],1,4) != ...
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#----Figure_04 K------------------------------------------------------------ #------------------------------------------------------------------------------- # This is the code for Figure 04 Panel K for the connectivity analysis for # Reinhard and Fukuda et al. 2024 # The first run might take long as all synapses...
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--- title: "Roche_Analysis_Diaz_Yohimbine" author: "Lukas von Ziegler" date: '2024-02-08' output: html_document --- ```{r setup, include=FALSE} knitr::opts_chunk$set(echo = TRUE) ``` # Analysis of Clustering Results of Yohimbine and Diazepam Experiments at Roche ```{r, message=FALSE, warning = FALSE} s...
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# EEG Power LMM analysis # this script does an LMM analysis of the effects of arousal and movement on the # ROI EEG spectral power in the classical frequency bands (delta, theta, alpha, beta, gamma) # 2024 by Antonin Fourcade # load packages ----------------------------------------------------------- library(ggdist)...
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library(tidyverse) library(janitor) ## Import datasets nacc.raw <- read_csv('data/nacc.csv') adni.raw <- read_tsv('data/adni.csv') adprs.raw <- read_tsv('~/Downloads/results_newfam/out/score/out_pgs.txt.gz', guess_max = 60000) %>% janitor::clean_names() pcs <- read_tsv('~/Downloads/results_newfam/out/score/out_pops...
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# ECG LMM analysis # this script does an LMM analysis of the effects of arousal and movement on the # ECG features (IBI, LF-HRV, HF-HRV) # 2024 by Antonin Fourcade # load packages ----------------------------------------------------------- library(ggdist) library(gghalves) library(raincloudplots) library(lme4) libra...
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library(dplyr) library(tidyr) library(stringr) library(ComplexHeatmap) library(ggplot2) library(tibble) library(reshape2) library(openxlsx) library(ggpubr) library(gridExtra) library(cowplot) library(ggprism) MD <- read.csv('Spots_metadata.csv', stringsAsFactors=FALSE) MD$Sample2 <- paste(MD$Patient,MD$Line, MD$Mouse...
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library(dplyr) library(ggplot2) library(ggrastr) library(patchwork) ########################## ###Gene expression full### ########################## dt.expr <- lapply(Sys.glob("raw data/*"), function(i) { res <- read.csv(i, row.names = 1) return(res) }) dt.expr <- do.call(rbind, dt.expr) pdf("output...
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lat_esq<-rep("ESQ",100) lat_dir<-rep("DIR",100) mov_rep<-rep("REP",100) mov_ped<-rep("PED",100) olho_oa<-rep("OA",100) olho_of<-rep("OF",100) pos_c<-rep("C",100) pos_f<-rep("F",100) pos_p<-rep("P",100) pos_o<-rep("O",100) idd<-c("I1","I2","I3","I4","I5","I6","I7","I8","I12","I13","I14","I15","I17","I18","I20","I21","I2...
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--- title: "Simulations for Causal Batch/Group Effects" author: "Eric W. Bridgeford" date: "`r Sys.Date()`" output: rmarkdown::html_vignette vignette: > %\VignetteIndexEntry{cb.simulations} %\VignetteEngine{knitr::rmarkdown} %\VignetteEncoding{UTF-8} --- ```{r setup, include = FALSE} knitr::opts_chunk$set( col...
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#' mochims__plot_validation_scatter #' #' Plot correlation with validation data. #' #' @param input_dt data.table with model free energy estimates (required) #' @param lit_inpath path to literature free energies (required) #' @param report_outpath output path for scatterplots (required) #' @param highlight_colour colo...
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--- title: "Sample loading and quality control" output: html_document: df_print: paged --- ### Loading Samples and set up Loading libraries Note: please make sure to use both Seurat v4.1.1 and SeuratObject v4.1.0 to reproduce this analysis, as later versions of either packages change the UMAP at the RunUMAP st...
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# Auteur : Rihab AZMANI # script Azim data setwd("/home/orlab/Desktop/Rihab/Dataset Azim et al") # pathway of dataset if (!requireNamespace("BiocManager")) install.packages("BiocManager") BiocManager::install() # install.packages('class', dependencies=TRUE) # install.packages('codetools', dependencies=TR...
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--- title: "axon_AP" author: "Franz Xaver Mittermaier" date: "2023-06-21" output: html_document --- This script plots the panels for the axonal AP shape changes in response to different subthreshold modulation paradigms.In brief, I conducted paired somato-axonal patch-clamp recordings. I then used somatic curre...
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# ================================================================ # Visualize Feature score distributions by Fribble # Session 2 only + feature-level sex differences # ================================================================ library(tidyverse) # ---------------------------------------------------------------...
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#----Figure_04_J---------------------------------------------------------------- #------------------------------------------------------------------------------- # This is the code for Figure 04 Panel J for the connectivity analysis for # Reinhard and Fukuda et al. 2024 # The first run might take long as all syna...
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#3g_Annotation_Pathway.R rm(list=ls()); options(stringsAsFactors = F) library(pSI); library(gProfileR); library(gplots); library(biomaRt); library(WGCNA); library(stringr); library(GENIE3) load("Chinese-Signed-networkConstruction-auto.RData") load("Chinese_human_brain_Adjust_Expr&Meta.rdata") load("BrainGVEx_human_br...
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--- title: "panel_dcg4" author: "Franz Xaver Mittermaier" date: "4 3 2022" output: html_document --- This script will plot the graphs for the DCG-IV experiments. In brief, I performed paired patch-clamp recordings.I identified synapses that were reliable and therefore showed no sub-threshold modulation. I the...
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#' Main neuroimaGene query #' #' Using a user supplied vector of genes (Ensembl ID's or HUGO names), this #' function queries the NeuroimaGene resource for all statistically significant #' GReX-NIDP associations and returns all findings as a data.table. #' @param gene_list List of genes to work as inputs. There are no...
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library(circlize) library(dendextend) library(openxlsx) library(stringr) library(devtools) library(ComplexHeatmap) library(grid) library(RColorBrewer) library(dendextend) library(dendsort) ### read data axonF<-read.table("../data/Fig5/axon_feature.txt") colnames(axonF)<-c('name','arbor_id','region','max_density','num_...
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#' mochims__get_model_results #' #' Get model results and coefficients. #' #' @param input_folder path to input folder with model results (required) #' @param normalisation_file path to normalisation file (required) #' @param RT constant (default:0.001987*(273+24)) #' #' @return data.table with model results #' @expor...
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--- title: "Gene Set Enrichment (*`r params$species.name`*)" author: "Bucao, Christabel Floi" output: html_document date: "`r Sys.Date()`" params: input.samples.path: "../../results/01_Filter_Samples" input.variability.path: "../../results/03_Variability_Plots" output.path: "../../results/07b_GO_cameraPR" speci...
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# --------------------------------------------------------------------------------- # # # # Hippocampal volumes in UK Biobank are associated with APOE only in older adults # # ...
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# Auxiliary functions to set arguments # # Package: meta # Author: Guido Schwarzer <guido.schwarzer@@uniklinik-freiburg.de> # License: GPL (>= 2) # chksetVar <- function(x, missing, replace, func, n = 0, args = NULL, oldname, warn, ...) { name <- deparse(substitute(x)) #...
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# docker run -ti --entrypoint /bin/bash -v /cis/home/ebridge2/Documents/research/graphstats_repos/causal_batch/:/causal_batch neurodata/cdcorr:0.0.1 # cd causal_batch/docs/causal_cdcorr_paper/Figure_reproduction/ require(tidyverse) require(jsonlite) require(np) demo_key <- read_json("../data/abcd/demo_key.json") site...
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--- title: "ProteoMill Report" date: "`r format(Sys.time(), '%a %d %b, %Y')`" output: html_document --- This report was automatically generated using the [ProteoMill](https://proteomill.com/) web tool. ```{r violin1, echo = FALSE, out.width = '60%', out.height= '40%'} if("Data summary" %in% input$p2){ if(!is.null(...
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library(Seurat) library(tidyverse) library(Matrix.utils) library(dplyr) library(Matrix) library(purrr) library(tibble) library(SingleCellExperiment) library(apeglm) library(DESeq2) library(DEGreport) library(magrittr) library(sva) #to be ran after updated SeqSeek Pipeline. With updated 'query.rds' object...
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lat_esq<-rep("ESQ",100) lat_dir<-rep("DIR",100) mov_rep<-rep("REP",100) mov_ped<-rep("PED",100) olho_oa<-rep("OA",100) olho_of<-rep("OF",100) pos_c<-rep("C",100) pos_f<-rep("F",100) pos_p<-rep("P",100) pos_o<-rep("O",100) idd<-c("I1","I2","I3","I4","I5","I6","I7","I8","I12","I13","I14","I15","I17","I18","I20","I21","I2...
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#!/usr/bin/env Rscript args<-commandArgs(TRUE) main_dir="/local1/work/ginkgo/scripts" genome <- args[[1]] user_dir <- args[[2]] status <- args[[3]] bm <- args[[4]] cm <- args[[5]] dm <- args[[6]] f <- as.numeric(args[[7]]) facs <- args[[8]] sex <- as.numeric(args[[9]]) library('ctc') library(gplots) library(plyr) ...
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#' Highlights and test the time-course of effects through crossvalidation #' #' This function is meant to implement, roughly and with no assurance of full compatibility #' the procedure proposed by Mathôt and Vilotijević (2022, *Behavior Research Methods*). #' First, each trial (i.e., one complete time series) is assig...
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#' mochims__plot_additive_trait_2state #' #' Plot additive trait for 2-state model. #' #' @param mochi_outpath path to MoCHI thermo model fit results (required) #' @param input_dt data.table with model free energy estimates (required) #' @param RT constant (default:0.001987*(273+24)) #' @param trait_name additive trai...
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--- title: "GO Enrichment (*`r params$species.name`*)" author: "Bucao, Christabel Floi" output: html_document date: "`r Sys.Date()`" params: input.samples.rds.path: "../../results/01_Filter_Samples" input.variability.rds.path: "../../results/03_Variability_Plots" output.path: "../../results/07_GO_Enrichment" sp...
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#' Description of summary measures available in R package \bold{meta} #' #' @description #' Description of summary measures available in R package \bold{meta} #' #' @details #' The following summary measures (argument \code{sm}) are recognised #' in R package \bold{meta}. #' #' \subsection{Meta-analysis of binary out...
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#' viewDist #' #' Visualise a mini-batch of image chips, masks, distance-to-boundary grids, #' and the resulting edge-weight surface for a DataLoader that supplies distance grids. #' #' Plots four panels stacked vertically: #' \enumerate{ #' \item RGB image chips arranged in a grid. #' \item Corresponding class mas...
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library(dplyr) library(ggplot2) library(ggrastr) library(ggrepel) ######################### ###Grubman volcanoplot### ######################### res <- read.csv("results/grubman_MAST_vulnerability_results.csv", row.names = 1) %>% mutate(DE = case_when(FDR < 0.05 & abs(coef) > 0.25 ~ "DE", ...
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--- title: "Centering covariance matrices" author: "Corson N. Areshenkoff" date: "`r Sys.Date()`" output: rmarkdown::html_vignette vignette: > %\VignetteIndexEntry{Centering covariance matrices} %\VignetteEngine{knitr::rmarkdown} %\VignetteEncoding{UTF-8} --- ```{r setup, include = FALSE} library(spdm) library(g...
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--- title: "Bimodality Test (*`r params$species.name`*)" author: "Bucao, Christabel Floi" output: html_document date: "`r Sys.Date()`" params: input.samples.rds.path: "../../results/01_Filter_Samples" input.variability.rds.path: "../../results/03_Variability_Plots" output.rds.path: "../../results/05_Bimodality_Te...
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library(ggplot2) library(dplyr) library(tidyr) library(faux) # create perfectly correlated vectors with a given vector (i.e. sample corelation) # Credits to: # https://stats.stackexchange.com/questions/15011/generate-a-random-variable-with-a-defined-correlation-to-an-existing-variables ### SET UP ### true_reliab...
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--- title: "Supplementary Figure 4" author: "Greg Duncan, Katie Emberley, and Jonathan Nelson" date: "`r format(Sys.time(), '%d %B, %Y')`" output: html_document: toc: yes toc_depth: 3 toc_float: true number_sections: yes theme: bootstrap df_print: paged code_folding: hide highlight: p...
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--- title: "panel_region_disease" author: "Franz Xaver Mittermaier" date: "2023-09-28" output: html_document --- This script plots the panels for the figure that compares the subthreshold modulation effect across different brain regions and disease backgrounds. These are the same experiments as in the "panel_d...
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# palettes for AI plot # ressources ---- # https://www.datanovia.com/en/blog/top-r-color-palettes-to-know-for-great-data-visualization/ # bootstrap palette ---- ## individual country palettes for data exploration ---- # transparent bootstrap value when <= 95 Ultra-fast bootstrap - to avoid overplotting rgb(0, 0, 1,...
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--- title: "Figure 0 Sims V2" output: html_document date: "2023-10-21" --- ```{r setup, include=FALSE} knitr::opts_chunk$set(echo = TRUE) ``` ```{r setup, include=FALSE} require(causalBatch) require(tidyverse) require(parallel) require(dplyr) source("../utilities/combat_gam.R") source("../utilities/combat_return.R")...
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### Frontend Modules ### suppressPackageStartupMessages(library(RColorBrewer)) suppressPackageStartupMessages(library(plotly)) suppressPackageStartupMessages(library(shiny)) suppressPackageStartupMessages(library(igraph)) suppressPackageStartupMessages(library(dendextend)) suppressPackageStartupMessages(library(shinyda...
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# create directories ------------------------------------------------------ #create output directory dir.create('downstream_analysis/differential_expression') outdir<-'downstream_analysis/differential_expression/' indir<-'counts/' # load libraries ---------------------------------------------------------- library(DE...
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# library library(zoo) library(gplots) library(stringr) library(data.table) library(optparse) # Parse options ## Set up command line argument parsing option_list = list( make_option(c("--bamdir"), type="character", default=NULL, help="Directory containing BAM files", metavar="directory") ) ## Parse the command lin...
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### OASIS-3 Retest case for Boney ### # April 2024 library(dplyr) library(stringr) library(ggplot2) OASIS3 <- read.csv("/Volumes/OneTouch/MRData/202301_MRIbones/OASIS3/OASIS3all.csv", header=F) #######sample selection############## #Keep MR data OASIS3_MR <- as.data.frame(str_subset(OASIS3$V1...
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--- title: "contig_assignment_by_correlation" author: "Siyuan Feng" date: "2/10/2021" output: pdf_document: fig_width: 8 fig_height: 6 --- ```{r setup, include=FALSE} knitr::opts_chunk$set(echo = TRUE) ``` # Load the dataset ```{r} setwd("/Users/siyuansmac/bioinfo/temp") df <- read.delim(file="mean_depth_...
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# File: IC50_mcmc.R # Author: Kelly Chang # based on code by Jose Vicente # Date: Oct 2017 # Version: 1.0 # # Description: R script to perform Markov-chain Monte Carlo (MCMC) # simulation for Hill equations modeling drug block of # ionic currents. T...
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# Copyright 2022 HYBRID Team INCIA, UMR5287, CNRS, Université de Bordeaux # Licensed under the Apache License, Version 2.0 (the "License"); # you may not use this file except in compliance with the License. # You may obtain a copy of the License at # http://www.apache.org/licenses/LICENSE-2.0 # Unless required b...
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#Alicia Petrany, draft as of 5.4.2024 #This file contains main functions #Install on machine with devtools::install() #'@title DEGage #'@description #'Tests for pairwise differential expression between two count distributions #' #'@param counts A dataframe with cells as columns and genes as rows. #'@param gro...
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#### Characteristics Table #### Coded: Benjamin Saef #### Date as of commenting and documentation - 05/28/2024 library(tidyr) library(data.table) library(RVAideMemoire) library(pROC) library(RColorBrewer) library(MuMIn) source("./Functions_for_Analysis.R") ##Set up project folders and out_project <- "/FNIH_Project_...
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--- title: "Test_exp" output: html_document --- ```{r} library(dplyr) library(tidyverse) library(cowplot) library(ggpubr) ``` #Cell death frm three batches, WT2 (WT68) ```{r} setwd("Z:/16-Our Papers/In Preparation/PD_Diabetes_Alise/Figures/FigureS2/originals/B,C") data_LDH <- readr::read_csv("LDH_ass...
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--- title: "TEBC faecal samples: shotgun taxonomic data exploration, cleaning and organisation" author: - "Kadi Vaher" - "Exploring the metagenomic taxonomic data in the TEBC samples" - "Making phyloseq objects of the species-level shotgun taxonomic data" date: '`r Sys.Date()`' output: html_document --- ```{r s...
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#!/usr/bin/env Rscript # ============================================================================== # == From "Summary" Table, launch plot generation on selected cells # ============================================================================== # ---------------------------------------------------------------...
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library(tidyverse) library(dplyr) headers <- read.table('/home/mgell/Work/abcd_pheno/phenotype/abcd_tbss01.txt', header = F, nrows = 1, as.is = T) NIHTBX <- read.table('/home/mgell/Work/abcd_pheno/phenotype/abcd_tbss01.txt', skip = 2) colnames(NIHTBX) <- headers # behs = c('src_subject_id','eventname', # '...
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--- title: "Marker genes and Proportion" output: html_document --- ```{r setup, include=FALSE} knitr::opts_chunk$set( echo = FALSE, warning = FALSE, message = FALSE ) ``` Load required packages ```{r} require(Seurat) require(data.table) require(tidyverse) require(circlize) require(ComplexHeatmap) require(ggp...
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library(dplyr) library(tidyr) library(stringr) library(STRINGdb) library(igraph) library(ggplot2) # for(i in 1:15){ # plot_hub_network(gene_list = 'Hs_all_15_GeneSpectraScore_95perc_list.rds', # GEP = i, # corr_file = "Hs_all_GEP_Corr_with_Expr.rds", # ...
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--- title: "TEBC faecal samples: calculating gut-brain and gut metabolic modules from shotgun functional data" author: - "Kadi Vaher" date: '`r Sys.Date()`' output: html_document --- ```{r setup, include=F, message=F} library(tidyverse) library(here) library(readr) # set paths knitr::opts_knit$set(root.dir=".", a...
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# Load required libraries library(pscl) library(MASS) library(randomForest) library(e1071) library(caret) library(Metrics) library(nnet) library(ggplot2) library(reshape2) # Load the dataset # Replace 'path/to/your/datafile.txt' with the actual file path mydata <- read.delim('path/to/your/datafile.txt', h...
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--- title: "SEFL10k5_Analysis" author: "Zach" output: html_document: fig_height: 4.5 fig_width: 4.5 highlight: kate number_sections: yes theme: journal toc: yes toc_depth: 6 editor_options: chunk_output_type: console --- #Set Global Options ```{r global_options} knitr::opts_chunk$set...
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###Script 19 #scGSEA library(msigdbr) library(escape) library(Seurat) library(Matrix) library(dplyr) library(ggplot2) set.seed(1234) #load seurat dataset dt.raw <- readRDS("output/atlas/non_integrated_neuronal_atlas.rds") dt.sct <- readRDS("output/atlas/integrated_neuronal_atlas.rds") dt.sct@assays$R...
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rm(list = ls(all = TRUE)) # edit to your filepath containing "list_frailty_indices.csv" and "list_final_variables.csv" # (i.e. where you place cloned git repo) wd <- "" out_dir <- paste0(wd, "/intermediate_files/") dir.create(file.path(wd, "intermediate_files"), showWarnings = FALSE) results_dir <- paste0(wd, "/scr...
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--- title: "panel_pre_drive_post_plasticity" author: "Franz Xaver Mittermaier" date: "2023-09-04" output: html_document --- Multineuron patch-clamp recordings were performed. Convergent microcircuit-motifs were identified. After measuring the baseline EPSP amplitude of synapses that made up the convergent motif...
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#20250101 update #Fixed a bug in the rs-number string. #-----Joint-Tissue-gene-expression-Imputation-(JTI)----- cat('\n---Joint-Tissue-gene-expression-Imputation-(JTI)---\n') library('glmnet') library("optparse") option_list = list( make_option("--tissue", action="store", default=NA, type='character', ...
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--- title: "Matching Conditional ComBat" author: "Eric W. Bridgeford" date: "`r Sys.Date()`" output: rmarkdown::html_vignette vignette: > %\VignetteIndexEntry{cb.correct.matching_ccombat} %\VignetteEngine{knitr::rmarkdown} %\VignetteEncoding{UTF-8} --- ```{r setup, include = FALSE} knitr::opts_chunk$set( colla...
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library(data.table) library(readxl) library(stringi) library(LDlinkR) library(flextable) library(magrittr) token <- Sys.getenv("LDLINK_TOKEN") MIN_MAF <- 0.005 MIN_R2 <- 0.97 ad_gwas_results <- fread("/data_global/summary_statistics/Bellenguez/GCST90027158_buildGRCh38.tsv.gz") ad_snps_old <- setDT(read_xlsx('raw_dat...
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#devtools::install_github("CeMOS-Mannheim/PlaquePicker") library(dplyr) # library(tidyverse) library(msiImporter) library(xml2) library(stringr) library(rayshader) path <- ".imzML" mis_path <- ".mis" tolerance <- 10 resulting_res <- 20 spot_dilation <- 1#.25 m_range <- c(100,900) # m_range <- c(650,800) new_me...
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--- title: "Estimating onsets using cluster statistics: simulation using EEG-like noise" author: "Guillaume A. Rousselet" date: "`r Sys.Date()`" output: # pdf_document: # fig_caption: no # number_sections: no # toc: yes # toc_depth: 2 github_document: html_preview: yes toc: yes toc_dep...
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--- title: "COLOC" author: "Jack Humphrey" date: "10/12/2023" output: html_document --- ```{r setup, include=FALSE} knitr::opts_chunk$set(echo = TRUE) library(tidyverse) library(patchwork) ``` ```{r} prep_coloc <- function( all_res, ld_res, LD = FALSE){ all_coloc_res <- read.table( all_res, header=TRUE) if(LD){...
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#subjobs args<-as.numeric(commandArgs(TRUE)) #load real GTEx eqtl results eqtl<-read.table('/data/c***/z***/projects/gtex/mr/twmr/liver/eqtl.txt',header = T,stringsAsFactors = F) eqtl<-eqtl[,c('gene_id','rsid','slope','slope_se','pval_nominal','ref_allele','eff_allele')] colnames(eqtl)<-c('gene_id','rsid','beta...
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library(magrittr) devtools::install_github('diegovalle/mxmaps') # Accumulated growing degree days for the year with a base temperature of 5 degrees Celsius. # Data was downloaded from https://sage.nelson.wisc.edu/data-and-models/atlas-of-the-biosphere/mapping-the-biosphere/ecosystems/growing-degree-days/, # then was c...
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library(nichenetr) library(Seurat) library(SeuratObject) library(tidyverse) library(dplyr) # Map clinical data to the metadata merge_metadata <- function(sobj, metadata){ meta_data_sex <- inner_join(sobj@meta.data, metadata) rownames(meta_data_sex) <- rownames(sobj@meta.data) sobj@meta.data <- meta_data_se...
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--- title: "Temporal Trajectory" output: html_document --- ```{r setup, include=FALSE} knitr::opts_chunk$set(echo = TRUE) # load required packages require(data.table) require(future) require(tidyverse) require(ggpubr) # directories data_dir = file.path("..", "Data") rdir = file.path("..", "Results") source("Helper_s...
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--- title: "Python troubleshooting" author: "Charly H. A. Billaud, Junhong Yu" date: "2026-09-02" output: rmarkdown::html_vignette vignette: > %\VignetteIndexEntry{Python troubleshooting} %\VignetteEngine{rmarkdown::render} %\VignetteEncoding{UTF-8} bibliography: references.bib --- ```{r setup, include=FALSE} kn...
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####################################################### ### Deep Brain Stimulation: STN vs GPi. ### Figures ### 2023 Katrin Petermann ####################################################### ## colors ## blue, green, red, orange, yellow cols <- c("#125773", "#368F86", "#F0523F", "#F59E3C", "#F5CF67") source("./code/g...
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#code to create a figure for Maaslin2 results of clinical covariates #analyses run in the script 16S_relative_abundance.Rmd #libraries library(tidyverse) library(ggpubr) library(cowplot) library(here) library(patchwork) library(readr) library(ggtext) source(here("src", "utils_kadi.R")) ##############################...
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--- title: "Association between breastfeeding and outcomes" author: "Giulio Centorame" format: html editor: visual --- This notebook contains the phenotypic association analysis between breastfeeding and our outcomes of interest. The results of this notebook are also available in Supplementary Tables 10 to 12 # Setu...
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--- title: "Figure1_kmeans_70Clusters" author: "Fabienne Rössler" date: '2023-02-27' output: html_document --- ```{r setup, include=FALSE} knitr::opts_chunk$set(echo = TRUE) ``` ```{r, message=FALSE, warning = FALSE} source("../DLCAnalyzer_Functions_v4.R") source("../UnsupervisedAnalysis_Functions.R") l...
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library(ggplot2) library(ggforce) library(scatterpie) save_dir_raw <- "Data/processed_data/simulations/merfish" merfish_counts <- read.csv(paste(save_dir_raw, "MERFISH/merfish_counts.csv", sep = "/"), header = TRUE, row.names = 1) merfish_counts <- as.matrix(merfish_counts) rownames(merfish_counts) <- seq(nrow(merf...
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optim_path='/home/z***/script/v8/utmost/' #args = commandArgs(trailingOnly=TRUE) ### optimization part ### grad_prep <- function(X, Y){ ## pre-calculate some metrics for gradient ## args ## X: a list of covariate matrices corresponding to each response ## Y: a list of response vectors ## value ...
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library(ggplot2) library(dplyr) library(tidyr) library(faux) # create perfectly correlated vectors with a given vector (i.e. sample cor.) # Credits to: # https://stats.stackexchange.com/questions/15011/generate-a-random-variable-with-a-defined-correlation-to-an-existing-variables ### SET UP ### #reliability <- c...
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contrastUI <- function(id) { ns <- NS(id) fluidRow( column(width = 4, box(width = NULL, title = "Set contrasts", status = "primary", solidHeader = F, helpText("Which treatments should be compared?"), selectInput(ns("contrast1"), label = "Treatment 1", choices = list("Treatme...
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#' Identifying spectra and spectral data points #' #' This function allows to identify the spectrum and the wavelength of a point #' in a plot produced by [plotspc()]. #' #' This function first finds the spectrum with a point closest to the clicked #' position (see [graphics::locator()]). The distance to the clicked #'...
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#' mochims_coupling_scatter_datasets #' #' Coupling scatterplots for multiple datasets. #' #' @param dataset_names character vector of dataset names (required) #' @param validation_list list of validation couplings (required) #' @param base_dir Base directory (required) #' @param output_dir Output directory (required)...
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### -------------------------------------------------------------------------~ ### ### plot methods ### ### -------------------------------------------------------------------------~ # Set generic ---------------------------------------------------------------- #' @noRd #' @export setGeneric("plot") # Functions ---...
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library(dplyr) library(tidyr) library(stringr) library(ComplexHeatmap) library(ggplot2) library(tibble) library(reshape2) library(openxlsx) library(ggpubr) library(gridExtra) library(cowplot) library(ggprism) MD <- read.csv('Spots_metadata.csv', stringsAsFactors=FALSE) MD$Sample2 <- paste(MD$Patient,MD$Line, MD$Mous...
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library(ggplot2) library(dplyr) library(tidyr) library(faux) # create perfectly correlated vectors with a given vector (i.e. sample cor.) # Credits to: # https://stats.stackexchange.com/questions/15011/generate-a-random-variable-with-a-defined-correlation-to-an-existing-variables ### SET UP ### #reliability <- c...
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#code to create PERMANOVA heatmap #plotting 16S ASV-level, and shotgun species- and GMM-level results all together #PERMANOVAs testing univariable relationships between clinical covariates and microbiota community composition #analyses were ran in scripts: #16S ASV-level: 16S_beta_diversity.Rmd #shotgun species-level: ...
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--- title: "Variability Jackknife (*`r params$species.name`*)" author: "Bucao, Christabel Floi" output: html_document date: "`r Sys.Date()`" params: input.rds.path: "../../results/01_Filter_Samples" output.rds.path: "../../results/02_Variability_Jackknife" species: "DRE" species.name: "Danio rerio" min.percen...
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#' Import RevMan 5 analysis data #' #' @description #' Reads analysis data from Cochrane intervention review created with #' RevMan 5 and creates a data frame from it. #' #' @aliases read.rm5 Fleiss1993_CR #' #' @param file The name of a file to read data values from. #' @param sep The field separator character (onl...
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#Alicia Petrany, 5/18/2023 #'@title QC_Simulation #'@description #'Performs quality control on user input for DEGage_simulation #'@param ngenes is the number of genes to be simulated total #'@param ndegs is the number of genes to be differentially expressed #'@param cellgroups is factor with integers correspond...
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#' @title Classify class and subclass #' @description Classify class and subclass. #' @param new_data Data input, single cell expression data. #' @param group_meta meta input #' @param ref_data Reference expression data for classication. #' @param ref_meta Reference metadata, must include column name with class_l...
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library(caret) library(glmnet) library(kernlab) library(plotly) library(dplyr) library(pROC) dbAlz <- read.csv("~/POSDOCTORADO/Python Seleccion Caracteristicas/Datasets_Con_OSampler/adnimerge-EObsNA_2_SanovsEnfermo_OSampler.csv") #dbAlz <- read.csv("~/POSDOCTORADO/Python Seleccion Caracteristicas/adnimerge-EOb...