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# Check that input checks are working test_that("addMDS errors", { tse <- makeTSE() assayNames(tse) <- "counts" # getMDS(tse, assay.type = "test") |> expect_error() addMDS(tse, name = 1) |> expect_error() addMDS(tse, name = c("test", "test2")) |> expect_error() addMDS(tse, name = NULL) |> ex...
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R
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#' cluster_strains(genes_df = NULL, normalize_length = FALSE, distmethod = "bray", cutoff = NULL) #' #' Clusters MAGs of a single working taxid into functional clades by Bray-Curtis #' dissimilarity of their per-Product gene-length profiles, hierarchical average-linkage #' clustering, and a dissimilarity cut. Used inte...
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R
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############## ### Script ### ############## # Run Firth Regression at each voxel independently. Due to the large data size this script needs to be run # in parallel without the for loop at each voxel independently. # (Code for UK Biobank application) ################# ### Libraries ### ################# library(brg...
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R
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#' plot_wordcloud_sample(featuredose_df = NULL, analysis = NULL, removeunclassifieds = TRUE) #' #' JAMSalpha function #' @export #Plot wordcloud of functional data plot_wordcloud_sample <- function(featuredose_df = NULL, analysis = NULL, removeunclassifieds = TRUE){ if (!(analysis %in% featuredose_df$Analysis)){ ...
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R
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test_that("applyByModule", { set.seed(123) tse <- TreeSummarizedExperiment::makeTSE() assayNames(tse) <- "counts" alpha.index <- c("observed", "shannon") expect_error( applyByModule( tse, "rows", "var1", addAlpha, index = alpha.index, min.group.size = 2 ),...
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library(Seurat) library(ggplot2) library(reshape2) library(tidyr) library(dplyr) library(hdf5r) visiumBetaPhase2Samples <- c("144105","144106","144107","144108","144111","144112","144113","144114", "151673", "151674", "151675", "151676") sample_objs <- list() for(i in visiumBetaPhase2Samples) { print(i) spatialObj...
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logger_message <- function( mess_str, file_name = NULL, indent = 0L, verbose = TRUE ) { # Write message to console and file if (is.null(file_name)) file_name <- .get_log_file() # Derive an indent string using two spaces for each indentation. indent_str <- strrep(" ", indent) # Date and tim...
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library(data.table) library(ggplot2) library(ggtext) library(tidyverse) ## https://danielroelfs.com/blog/how-i-create-manhattan-plots-using-ggplot/ args <- commandArgs(T) gwas_data <- fread( "run_folder/exon_distance/concated/Cns.Toxicity~rest_annotated.logistic_distance", sep="\t", ) selected_genes <- read.csv...
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############################################################# ################### TIME SERIES MAPPINGS #################### ############################################################# ####################################################### #### load time series mapping algorithms source("vg_algorithm.R") source("qg...
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# written by Susan Holmes \email{susan@@stat.stanford.edu}. # Adapted for phyloseq by Paul J. McMurdie. # Adapted for mia by Felix G.M. Ernst #' @importFrom DelayedArray rowSums .JSD <- function(x, y){ # Function to compute Shannon-Jensen Divergence # x and y are the frequencies for the same p categories # ...
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#' replace_Sample_names_in_SEobj(curr_SEobj = NULL, Sample_name_mapping = NULL, oldname_column = "Sample", newname_column = NULL) #' #' Renames samples in JAMS SummarizedExperiment objects safely. #' Use with care and at your own risk #' @export replace_Sample_names_in_SEobj <- function(curr_SEobj = NULL, Sample_name...
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# Don't perform any further tests on CRAN due to running time. testthat::skip_on_cran() testthat::skip_on_ci() debug_flag <- FALSE exp_dir <- file.path(tempdir(), "familiar_intro_test") testthat::test_that( "Basic example works", { if (!debug_flag) on.exit(unlink(exp_dir, recursive = TRUE), add = TRUE) ...
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if(version$major<3 || (version$major==3 && version$minor<2.0)){ stop(paste("WARNING! muxViz requires R 3.2.x or higher in order to work properly. \nPlease update your R framework.\n")) } if(!require(devtools)){ install.packages("devtools") } if(!require(shiny)){ install.packages("shiny") library(devtoo...
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#' Network inference module: Load network #' #' This function loads a specified network (networkName) and filters for non-significant regulatory links (pValCutoff). #' @param networkName Name of the network #' @param pValCutoff Cutoff for significant links. Values from zero (most sparse network) to one (full network) ...
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#' print_table(tb=NULL, tabletitle=NULL, fontsize=6, numrows=20) #' #' JAMSalpha function #' @export print_table <- function(tb = NULL, tabletitle = NULL, fontsize = 6, numrows = 20){ if (class(tb)[1] != "data.frame"){ stop("Table must be a data frame") } #Define function to wrap text wrap_ce...
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#' loadobj(objfn = NULL, never_used_columns = c("AntiFam", "CDD", "Coils", "FunFam", "Gene3D", "PANTHER", "Phobius", "ProSitePatterns", "SFLD", "SignalP_EUK", "SignalP_GRAM_NEGATIVE", "SignalP_GRAM_POSITIVE", "SMART", "TIGRFAM", "MetaCyc") #' JAMSbeta helper function used by load_jamsfiles_from_system. #' #' Do not fid...
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#!/usr/bin/Rscript ################################################################################################################### #### Script to perform scaling on complete networks ################################################################################################################### library(data.ta...
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########################################## ## Retinol GWAS meta - summary statistics QC and harmonisation ## RARE VARIANTS ## William Reay (2022) ########################################## setwd("~/data/users/william/Meta_retinol_GWAS/") library(dplyr) library(data.table) ## INTERVAL raw - 11132 is max number of...
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# X (IV) -> HIV.status # Y (DV) -> total PHQ-9 score # M (mediator) -> biomarker 'conc' med.df <- data.frame( label = character(0), estimate = numeric(0), ci.min = numeric(0), ci.max = numeric(0), p.value = numeric(0), stringsAsFactors = F ) semdata <- blooddata ## Scale all biomarkers, ag...
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################################## # Visualize patient labels for UMAP in Supplementary Figure 6a. # Updated: 2021.05.10 # Author: Kevin J. ################################### mybasedir = "/Users/johnsk/github/" setwd(mybasedir) ################################### # Necessary packages: library(tidyverse) library(Seur...
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R
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#' Create a \code{TreeSummarizedExperiment} object from a phyloseq object #' #' @inheritParams convertFromBIOM #' #' @details #' \code{convertFromPhyloseq} converts \code{phyloseq} #' objects into #' \code{\link[TreeSummarizedExperiment:TreeSummarizedExperiment-class]{TreeSummarizedExperiment}} objects. #' All data sto...
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R
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# X (IV) -> HIV.status # Y (DV) -> total PHQ-9 score # M (mediator) -> biomarker 'conc' # covariates: age and gender med.df <- data.frame( label = character(0), estimate = numeric(0), ci.min = numeric(0), ci.max = numeric(0), p.value = numeric(0), stringsAsFactors = F ) semdata <- blooddata ...
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#' @title anndataToGiotto #' @description Converts a spatial anndata (e.g. scanpy) .h5ad file into a Giotto object #' @param anndata_path path to the .h5ad file #' @param metadata_cols metadata columns to include #' @param instructions giotto instructions #' @param \dots additional parameters to \code{\link{createGi...
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############################## ## RBP4 only IV ## FinnGen r8 ## Dr William Reay (2023) ############################## library(TwoSampleMR) library(data.table) library(dplyr) library(ggplot2) setwd("~/Desktop/Retinol_GWAS/MR_all_cis_acting_SNPs/FinnGen_r8_MR/") ## Harmonise data to generate heterogeneity statisti...
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--- title: "02_decoupleR_formatting_prior" author: "Jordan Whitlock" date: '2023-05-15' output: html_document --- ```{r} set.seed(2178) library(here) library(reshape) source(here("src/functions/functions.R")) ptm <- proc.time() ``` ```{r} # make list of expression files needed to loop through files <- list.files(her...
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# Don't perform any further tests on CRAN due to time of running the complete test. testthat::skip_on_cran() testthat::skip_on_ci() debug_flag <- FALSE # Generic test. familiar:::test_plots( plot_function = familiar:::plot_model_signature_occurrence, not_available_no_samples = FALSE, not_available_all_predictio...
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R
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# This contains the archiving function for creating the zip files. We move it # here so that CRAN doesn't get antsy. This is not a function that should be # used (or visible to) users, and is not part of familiar. test_run_archive_experiment <- function(parameters) { # Create data. data <- familiar:::test_create_g...
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#' sort_contigs_into_bins(opt = NULL) #' #' JAMSalpha function #' @export sort_contigs_into_bins <- function(opt = NULL, sortedbamfile = NULL){ #Do MetaBAT if applicable if (opt$bin_contigs_with_metabat){ setwd(opt$covdir) if (is.null(sortedbamfile)){ sortedbamfile <- paste(paste(o...
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R
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# computes network flow/impact matrix of each gene on each other gene for each sample # outputs in TrainNetwork-*/NetworkPropagation/NetworkFlow/ library(parallel) basePath = "/data/bcu_projects/MelBrainSys_PostdocProject_Gruetzmann/publications/2022-my-MelBrainSys-paper/scripts-etc-for-publication/" myPath = paste0(...
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test_that("getDysbiosis and addDysbiosis", { data(Tengeler2020, package = "mia") tse <- Tengeler2020 res <- getDysbiosis(tse, col.var = "patient_status", reference = "Control") expect_s4_class(res, "DataFrame") expect_identical(rownames(res), colnames(tse)) expect_identical(colnames(res), "media...
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#' #' makes one file of seperate edgelist files #' #' #' @param dir the directory of the files #' @param pattern the pattern the files have in common #' @param file_ext the extension of the files with the given input pattern (e.g txt, csv) #' @param file_name which file name to give to the made file (withou...
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# Don't perform any further tests on CRAN due to time of running the complete test. testthat::skip_on_cran() testthat::skip_on_ci() debug_flag <- FALSE familiar:::test_export( export_function = familiar:::export_prediction_data, not_available_all_predictions_fail = FALSE, not_available_some_predictions_fail = F...
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#Infer the Last Known Taxon (LKT) #' infer_LKT #' #' Infers the Last Known Taxon (LKT) from a taxonomic table or dataframe containing taxonomic information and adds an LKT column to the dataframe. #' @export infer_LKT<-function(taxtable){ dunno<-c("Unknown", "Unclassified") taxtable$LKT<-rep("Unclassified", le...
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# xml2 is required to . if (!rlang::is_installed("xml2")) testthat::skip() # Find path to configuration file in package. config <- system.file("config.xml", package = "familiar") # Load the configuration file config <- familiar:::.load_configuration_file(config) # Check whether the main branches have the correct nam...
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library(ggplot2) library(tidyverse) library(ggtext) args <- commandArgs(T) assoc = args[1] df_struc <- read.csv( "/home/joel/Documents/swedegene/WGS_pipeline/master/structural_analysis/data/gene_struct.csv", sep = "\t", as.is=T, check.names = F, stringsAsFactors = F) #assocs <- read.table("/home/joel/Documents/swe...
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library(data.table) library(ggplot2) library(ggtext) library(tidyverse) library(qvalue) df_genes <- read.csv("local_data/burden_results/burden_vf_threshold_full_results.tsv", sep = "\t", as.is=T) df_genes_unfiltered <- df_genes df_genes %>% filter(p != 1 & p != 0) -> df_genes genes <- fread( "/home/joel/Documents/R...
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## Use testdata to summarise descriptive statistics for PHQ-9 scores ## LINEAR REGRESSION OF PHQ-9 SCORE WITH HIV STATUS summary(lm(total ~ HIV.status, data = alldata)) summary(lm(total ~ HIV.status + age + gender, data = alldata)) summary(lm(scale(total) ~ HIV.status, data = alldata)) summary(lm(scale(total) ...
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library(Rtsne) library(data.table) library(ggplot2) library(lisi) library(ggpubr) library(dplyr) library(cluster) library(factoextra) library(RColorBrewer) library(randomcoloR) embedding_clust=function(emb){ latent<-fread(emb,header=F) gene<-fread("./data/node_order.txt",header=F) input<-cbind(gene,latent)...
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# test fMRI univariate effect using functional ROI: lOFC rm(list = ls()) source('Setup.R') usedir = dirname(getwd()) figDir = file.path(usedir,'Figs') SubInfo = read.xlsx(file.path(usedir,'SourceData.xlsx'),'SubjectConds') UseTMSConds = SubInfo$Cond[SubInfo$Excluded==0] Subs = SubInfo$Sub[SubInfo$Excluded==0] ## re...
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#****************************************************************** #Plot and compute markers # genes1 <- c('SLC17A6', 'GAD1', "SLC6A3", "TH", "SLC18A2", 'DCC', 'GALNTL6', 'RIT2', 'RBFOX3', "AQP4", "C3", "MOG", 'VCAN', 'FLT1') genes1 <- genes1[genes1 %in% genes$Symbol] features1 <- genes$Geneid[match(genes1, genes$...
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context("rarefyAssay") test_that("rarefyAssay", { seed = 1938 set.seed(seed) data(GlobalPatterns, package="mia") tse.subsampled <- rarefyAssay( GlobalPatterns, sample = 60000, name = "subsampled", replace = TRUE) # check class expect_s4_class(tse.subsampled...
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#' Data loader module: Create basic folder structure #' #' This function creates the standardized folder structure used by regNet for network inference, prediction, and network propagation. #' @param projectName Name of project folder #' @param path Directory where the project folder is created #' @param output Show p...
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context(".estimate_richness") test_that(".estimate_richness", { skip_if_not(requireNamespace("vegan", quietly = TRUE)) data(esophagus, package="mia") indices <- c("ace", "chao1", "hill", "observed") tse <- addAlpha(esophagus, index = indices, detection = 1) cd <- colData(tse) expect_equal(un...
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library(data.table) library(tidyverse) phenofile <- read.csv( "local_data/phenofile", sep = "\t", stringsAsFactors = F, check.names = F) excluded <- c("RI-1933-4606", "RI-1933-1457", "RI-1933-1334", "RI-1933-1315", "RI-1933-1096", "RB-1745-...
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#Doublet prediction library(scDblFinder) library(scater) dblOutdir <- 'dblFinder/' #First merge un-stable clusters C12 and C13 to C0 Ident_final = 'Cluster_final' SeuratObject@meta.data[, Ident_final] = as.character(SeuratObject@meta.data[, Ident1]) SeuratObject@meta.data[SeuratObject@meta.data[, Ident_final] %in% c('1...
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# Don't perform any further tests on CRAN due to time of running the complete # test. testthat::skip_on_cran() testthat::skip_on_ci() debug_flag <- FALSE # Generic test. Note that confusion matrices can be created if only one sample # is present. familiar:::test_plots( plot_function = familiar:::plot_confusion_matr...
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args <- commandArgs() #extract the argument given on the command line print(args) expr_table_dir <- args[6] #complete directory of input expression table output_dir <- args[7] #directory (+ name) of output table packages_dir <- args[8] #directory of R packages functions_dir <- args[9] #complete directory of the ...
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# Don't perform any further tests on CRAN due to running time. testthat::skip_on_cran() # power.transform and other packages are required. if (!rlang::is_installed("power.transform")) testthat::skip() # Create data.table. data <- familiar:::test_create_good_data( outcome_type = "binomial", to_data_object = FALSE ...
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# Temporary version --- use with cautions # ymat : a V times N matrix of imaging data (V: # of vertices, N: # of images) # mod : a N times p covariate matrix (p: # of covariates) # : It can be generated easily by using the model.matrix() function. # K : a N times N matrix specifyin...
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library(ggplot2) library(plotly) library(ggtext) library(tidyverse) library(ggrepel) args <- commandArgs(T) selected_subset = args[2] hla_assoc_df <- read.csv(args[1], sep="\t", as.is = T, check.names = F) hla_assoc_df$PVALUE <- as.numeric(hla_assoc_df$PVALUE) hla_assoc_df <- hla_assoc_df[!is.na(hla_assoc_df$PVAL...
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## read-sim.R -- contaminated read simulation using real Illumina qualities NUCLEOTIDES <- c('A', 'T', 'C', 'G') #adapters <- list("solexa_adapter_1"="AGATCGGAAGAGCTCGTATGCCGTCTTCTGCTTG") adapter <- "AGATCGGAAGAGCTCGTATGCCGTCTTCTGCTTG" #adapter <- "TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT" set.seed(0) addErrors <- # give...
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# LOADING LEIDA DATA df <- readr::read_csv(file = './data/df_LEiDa.csv') %>% dplyr::select(-...1) %>% dplyr::mutate(ttime = ttime + 1) %>% dplyr::mutate(patTags = stringr::str_replace_all(patTags, "b'sub-", "'"), patTags = stringr::str_remove_all(patTags, "'"), ses = stringr:...
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################################### ## Manhattan plot - retinol (METSIM+INTERVAL) & All three meta ## William Reay (2022) ################################## library(CMplot) library(data.table) library(dplyr) setwd("~/Desktop/Retinol_GWAS/") MET_INT_input <- fread("Meta_analyses/Common_var/Stouffers_METSIM_INTERVA...
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library(ggplot2) library(lavaan) reg_data= read.table("./Study2_behavioral_data.txt",header=T) out <-data.frame() for(i in unique(reg_data$Subject) ){ sub_dat <- reg_data[reg_data$Subject==i,] out<-rbind(out,scale(sub_dat,center = T,scale=F)) } SEM_data = data.frame(cbind(scale(reg_data$Coplayer_cost),scale(reg...
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#' make_antibiogram_experiment(mgseqresfinder = NULL, SEobjresfinder = NULL) #' #' Agglomerates data from a resfinder SEobj or mgSeq object to return an antibiogram-style mgSeq or SummarizedExperiment object #' @export make_antibiogram_experiment <- function(mgseqresfinder = NULL, SEobjresfinder = NULL){ if (is.n...
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folder_name='FABP7_centeratpromoter' input_path = paste0('/scratch/users/banwang3/references/outputs/',folder_name,'/sei_pantro6/sei/') input_path1=paste0('/scratch/users/banwang3/references/outputs/',folder_name,'/sei_pantro6/sei1/') input_path2 = paste0('/scratch/users/banwang3/references/outputs/',folder_name,'/sei/...
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library(stringr) library(dplyr) library(ggplot2) firstup <- function(x) { substr(x, 1, 1) <- toupper(substr(x, 1, 1)) x } output_path='/scratch/users/banwang3/celllines/scripts/RScripts/Rplots/' GSEA=read.table('/scratch/users/banwang3/celllines/scripts/RScripts/AGSEA_MWU_p-val_SignTest_Specific_025_test.csv',sep='...
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# lag autocorrelation output$lag_plot = renderPlot({ req(input$lag_dataset, input$lag_series) dataset = data.table() values = data.table() refs = data.table() for (s in input$lag_series) { .s = data$series[[input$lag_dataset]][[s]] ref.val = acf(data$raw[[input$lag_data...
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library(data.table) library(ggplot2) library(ggtext) library(tidyverse) library(qvalue) library(ggrepel) args <- commandArgs(T) mytest <- args[2] df_genes <- read.csv("local_data/burden_results/burden_dynamic_threshold_full_results.tsv", sep = "\t", as.is=T) df_genes %>% filter(test == myte...
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#' @include FamiliarS4Generics.R #' @include FamiliarS4Classes.R NULL # familiarMetricBrier ---------------------------------------------------------- setClass( "familiarMetricBrier", contains = "familiarMetric", prototype = methods::prototype( metric = "brier", outcome_type = NA_character_, name =...
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library(circular) ## data nameExp = "NPA_stich_3" str_zone = "zoneA" ## parameters σ2_flock = 1.5 σ2_stream = 1.0 ## loading folderDataZone = "../data_tracking/step3_data_zone/" nameFile = paste0(folderDataZone,nameExp,"/df_velocity/",nameExp,"_",str_zone,".csv") df = read.csv(nameFile, header = TRUE) θ = -df$θ par...
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################## GOAL: DETERMINE WHETHER ANY BIOMARKERS INTERACT SIGNIFICANTLY WITH GENDER FOR PATH A AND PATH B ## before running this script - run "mri-data" and "biomarkerdata" scripts to get processed and cleaned biomarker values ## now: merge all biomarkers into one dataframe with PID, age, gender, HIV.statu...
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# Cluster stability and robustness analysis by sub-sampling subClusterDir = 'scclust/' source('misc.R') vars.to.regress = c('Sex', 'Age', 'PMI') so1 <- CreateSeuratObject(counts = GetAssayData(SeuratObject, slot = 'counts'), min.cells = 0, min.features = 0, names.field = 2, names.delim = '.', meta.data = SeuratObject@m...
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--- title: "Multilayer motifs" output: rmarkdown::html_vignette vignette: > %\VignetteIndexEntry{Multilayer motifs} %\VignetteEngine{knitr::rmarkdown} %\VignetteEncoding{UTF-8} --- ```{r, include = FALSE} knitr::opts_chunk$set( collapse = TRUE, comment = "#>", fig.path = "../man/figures/" ) ``` ```{r loa...
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#' fix_feats2glomby_feats(feats2glomby_feats = NULL, glomby = NULL) #' #' Provides the correct algorithm for agglomerating taxonomic objects. This function is used by agglomerate_features and retrieve_features_by_taxa. No not attempt to use it outside of this context. #' @export fix_feats2glomby_feats <- function(feat...
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#' annotate_contigs #' #' JAMSalpha function #' @export annotate_contigs <- function(opt = NULL){ #Set working directory to workdir setwd(opt$workdir) #Write a copy of contigs to be annotated to the system flog.info("Writing contigs for annotation.") write.fasta(sequences = opt$NHcontigs_sequence,...
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CleanMean=function(ymat, distmat, cortex, sacf, max.radius, nperm = 5000, alpha = 0.05, alternative = "two.sided", seed = NULL, nngp = T, ...
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# First test if all selectable learners are also available familiar:::test_all_vimp_methods_available( vimp_methods = familiar:::.get_available_glmnet_ridge_vimp_methods(show_general = TRUE) ) familiar:::test_all_vimp_methods_available( vimp_methods = familiar:::.get_available_glmnet_lasso_vimp_methods(show_general...
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# Perform linear regression to examine the association between handgrip strength and cognition # Inputs to the script: # 1) datafile: name and path of spreadsheet containing demographic, cognition and handgrip strength data # 2) outputfile: name and path of output spreadsheet containing results of the linear regressio...
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library(parallel) library(ArchR) library(gUtils) library(pbmcapply) library(dplyr) args <- commandArgs(TRUE) #setwd("./analysis/GM12878_merged_noerror") # frag_file <- "./GM12878_merged_fragment.bed.gz" # peak_file <- "./dscNanoATAC_GM12878_noerror_ArchR_peaks_local500k_q0.01_rep2.txt" frag_file <- args[1] peak_file...
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library(ggplot2) library(lavaan) reg_data= read.table("./Study2_behavioral_data.txt",header=T) out <-data.frame() for(i in unique(reg_data$Subject) ){ sub_dat <- reg_data[reg_data$Subject==i,] out<-rbind(out,scale(sub_dat,center = T,scale=F)) } SEM_data = data.frame(cbind(scale(reg_data$Coplayer_cost),scale(reg...
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library("muxViz") #Or build by specifying layers Layers <- 5 Nodes <- 100 NodeTensor <- list() g.list <- list() g.list[[1]] <- igraph::barabasi.game(Nodes, m = 1, directed = F) #generate a second layer, with 25% edge overlap, while preserving degree distribution g.list[[2]] <- GetRewiredLayerWithOverlappingEdges(g...
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library(data.table) library(ggplot2) library(ggtext) library(tidyverse) library(qvalue) library(ggrepel) args <- commandArgs(T) mytest <-"Cns.Toxicity~rest" df_genes <- read.csv("local_data/burden_results/burden_vf_threshold_full_results.tsv", sep = "\t", as.is=T) df_genes %>% filter(p != 1 & p != 0) -> df_genes df_...
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testthat::skip_on_cran() testthat::skip_on_ci() debug_flag <- FALSE # Test that creates a single naive model. familiar:::integrated_test( experimental_design = "fs+mb", vimp_method = "no_features", cluster_method = "none", imputation_method = "simple", estimation_type = "point", parallel = FALSE, debug ...
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#' @name #' addPCA #' #' @title #' Perform principal component analysis (PCA) #' #' @description #' Perform principal component analysis (PCA). These functions are wrappers #' for \code{\link[scater:runPCA]{scater::calculatePCA}}. #' #' @details #' These functions are wrappers for #' \code{\link[scater:runPCA]{scater::...
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.gini_dominance <- function(x, w=rep(1, length(x))) { # See also reldist::gini for an independent implementation x <- as.vector(x) o <- order(x) x <- x[o] w <- w[o]/sum(w) p <- cumsum(w) nu <- cumsum(w * x) n <- length(nu) nu <- nu/nu[[n]] sum(nu[-1] * p[-n]) - sum(nu[-n] * p[-1...
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library("muxViz") #Or build by specifying layers Layers <- 3 Nodes <- 90 NodeTensor <- list() #Generate an edge-colored network with SBM structure g1 <- erdos.renyi.game(40, log(40)/40) g2 <- erdos.renyi.game(30, log(30)/30) g3 <- erdos.renyi.game(20, log(20)/20) g.list <- list() g.list[[1]] <- g1 %du% delete_ed...
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args <- commandArgs() #extract the argument given on the command line print(args) input_dir <- args[6] # directory folder of input files input_pattern <- args[7] #pattern shared by all input files output_dir <- args[8] #directory folder and shared pattern for output files packages_dir <- args[9] #directory of R ...
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library(gUtils) ## prepare a Seqinfo object sl <- hg_seqlengths(BSgenome.Hsapiens.UCSC.hg19::Hsapiens) si <- Seqinfo(seqnames=names(sl), seqlengths=sl, genome="hg19") isCircular(si) <- rep(FALSE, length(sl)) ## download data from UCSC Table Browser to include as example data in gUtils library (rtracklayer) mySession ...
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############## ### Script ### ############## # Run independent Firth regression models for every voxel j = 1,...,M (Code for simulation study). ################# ### Libraries ### ################# library(brglm2) ################# ### Constants ### ################# # Number of dataset to perform analysis on. sim ...
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#' @include FamiliarS4Generics.R #' @include FamiliarS4Classes.R NULL setClass( "familiarCorrelationVimp", contains = "familiarVimpMethod" ) .get_available_correlation_vimp_methods <- function(show_general = TRUE) { return(c("pearson", "spearman", "kendall")) } # is_available ------------------------------...
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skip_if_not_installed("biomformat") # Get default taxonomy ranks (importTaxpasta sets ranks based on data) default_ranks <- getTaxonomyRanks() test_that("a complete BIOM file can be loaded without error", { expect_no_error( suppressWarnings({ importTaxpasta(system.file("extdata", "complete.biom", package ...
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setwd("/data/bcu_projects/MelBrainSys_PostdocProject_Gruetzmann/publications/2022-my-MelBrainSys-paper/scripts-etc-for-publication/") dataPath = "regNet/Data/" trainingSetRatio = 3/4 # how many samples used for training, the remainder are used for test data # full data set gene expression fullExprDataFile = paste0( ...
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# If you would like to use this code, please cite our Jove paper: # Martianova, E., Aronson, S., Proulx, C.D. Multi-Fiber Photometry to Record # Neural Activity in Freely Moving Animal. J. Vis. Exp. (152), e60278, # doi:10.3791/60278 (2019). # https://www.jove.com/video/60278/multi-fiber-photometry-to-record-neur...
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library("muxViz") Layers <- 4 Nodes <- 100 #Before doing this for data, I recommend to play a bit with smaller multilayers. #There is a function that you can call to generate simple random multiplex networks: # #GetSampleMultiplex <- function(Layers, Nodes, p) # #where p is the wiring probability of Erdos-Renyi net...
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############## ### Script ### ############## # Run code to combine bootstrap samples into matrices to acquire sample from posterior distribution. # (Code for UK Biobank application) ################# ### Libraries ### ################# library(oro.nifti) ################# ### Constants ### ################# # Set ...
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# A simple example of a rejection algorithm for demographic inference of two parameters. # This function returns ndraws from the posterior distribution of the # time of expansion and f (the ratio of ancestral population size to present population # size) conditional on the mean TD being within eps of an # observed v...
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library("muxViz") set.seed(12345) #Or build by specifying layers Layers <- 3 Nodes <- 90 NodeTensor <- list() #Generate an edge-colored network with SBM structure g1 <- erdos.renyi.game(40, log(40)/40) g2 <- erdos.renyi.game(30, log(30)/30) g3 <- erdos.renyi.game(20, log(20)/20) g.list <- list() g.list[[1]] <- ...
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library("muxViz") #Comment this line to generate different networks set.seed(12345) #Or build by specifying layers Layers <- 3 Nodes <- 90 NodeTensor <- list() #Generate an edge-colored network with SBM structure g1 <- erdos.renyi.game(40, log(40)/40) g2 <- erdos.renyi.game(30, log(30)/30) g3 <- erdos.renyi.game(2...
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library(stringr) library(ggplot2) library(patchwork) library(argparse) parser <- ArgumentParser() parser$add_argument("--generator", default="FABP7") parser$add_argument("--cutoff",type="integer", default=0.5) args <- parser$parse_args() foldername=args$generator cutoff=args$cutoff input_path=paste0('/scratch/users/ban...
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updateCurrentVariableSelections = function () { variables = names(data$raw[[input$data_dataset]]) updatePickerInput(session, "data_plot_x", choices = variables, selected = data$meta[[input$data_dataset]]$time) updatePickerInput(session, "data_plot_y", choices = variables, selected = input$data_plot_y...
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req_packages <- c("AnnotationDbi", "DESeq2", "devtools", "doParallel", "dynamicTreeCut", "edgeR", "flashClust", "foreach", "ggdendro", "ggrepel", "ggplot2", "igraph", "limma", "MODA", "openxlsx", "org.Hs.eg.db", "plyr", "preprocessCore", "Rcpp", "r...
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#!/usr/bin/env Rscript set.seed(2178) # Load necessary libraries library(dplyr) library(decoupleR) library(CoSIA) #source("/data/user/jbarham3/230323_JW_DiseaseNetworks/src/functions.R") # Fetch command line arguments args <- commandArgs(trailingOnly = TRUE) gtex_file <- args[1] prior_net <- args[2] min_n <- as.nume...
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nest_fo <- function(tbl, vars, foVar){ require(dplyr) require(tidyr) require(janitor) vars_ <- dplyr::syms(vars) nested_fo <- tbl %>% dplyr::rename('clus' = all_of(foVar)) %>% dplyr::group_by(!!!vars_) %>% dplyr::summarise(clusVec = list(clus)) %>% dplyr::ungroup() %>% dplyr:...
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context("addDPCoA") test_that("addDPCoA", { skip_if_not(require("ade4", quietly = TRUE)) data(esophagus, package="mia") # esophagus <- addDPCoA(esophagus) expect_named(reducedDims(esophagus),"DPCoA") expect_true(is.matrix(reducedDim(esophagus,"DPCoA"))) expect_equal(dim(reducedDim(esophagus,...
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library(stringr) folder_name='GAD1_centeratHAR' input_path=paste0('/scratch/users/banwang3/references/outputs/',folder_name,'/sei/') output_path=paste0('/scratch/users/banwang3/references/outputs/',folder_name,'/sei/') id='hg38_all' input_path1=paste0(input_path,id,'/') df1 = list.files(input...
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############################################################# ########### MAIN PROCEDURE FOR CLUSTERING ANALYSIS ########## ############################################################# ## auxiliary variables n_reps <- 10 data <- normetrics[, c(idxs, ncol(normetrics))] ## look for NA values na <- c() for(nn in 1:(n...
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library(stringr) input_path='/scratch/users/banwang3/celllines/Enrichment_test/ATAC_fortau/Unfiltered/' allfiles = list.files('/scratch/users/banwang3/celllines/Enrichment_test/ATAC_fortau/Unfiltered/',pattern='.txt') includeSKM=T if (includeSKM){ celltypes=c('CM','MN','HP','PP','SKM') SKM='includeSKM' }else{ ...
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# pull together human SETBP1 targets across data sets: #* Obtained gene list of targets from msigdb SETBP1 target list #* (https://www.gsea-msigdb.org/gsea/msigdb/human/download_geneset.jsp? #* geneSetName=SETBP1_TARGET_GENES&fileType=TSV). The target list stored #* in cheaha at '221018_Setbp1_msigdb_targets.csv' at /d...
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basePath = "/data/bcu_projects/MelBrainSys_PostdocProject_Gruetzmann/publications/2022-my-MelBrainSys-paper/scripts-etc-for-publication/" setwd(basePath) neededSamples = c("P03_Br","P03_Lu", "P04_Br", "P04_Sk_GA", "P08_Br", "P08_St_GA", "P08_St_BA", "P08_St_YA", "P16_Br", "P16_Lu", "P18_Br", "P18...