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69b8b05c469910316a52ded853d69a561002a472d81c9d0c6319ba701296dca5
R
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# statistical analysies for low freq DBS project with Alex # --- Preparation ----------------------------------------------------------- # get local functions and constants source("local-functions.R") source("local-constants.R") # set orthogonal contrast settings options(contrasts=c("contr.sum","contr.poly"...
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R
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#' Print method for task_error object #' #' task_error are objects that result from failed methods #' #' @param x a task_error object #' @param ... not used #' #' @return None #' #' @export #' @keywords internal print.task_error <- function(x, ...) { cat( glue::glue( "error at step: '{x$error_lo...
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R
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library(tidyverse) library(magrittr) setwd(dirname(rstudioapi::getActiveDocumentContext()$path)) files <- fs::dir_ls("raw_data/") tb <- read_tsv(files, id = "path") summary <- tb %>% group_by(path) %>% summarise(acc = mean(correct)) tb_subset <- tb %>% filter(path %in% summary$path[which(summary$acc > 0.7)...
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R
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args <- commandArgs(trailingOnly = TRUE) stopifnot(length(args) == 5L) pkgload::load_all(file.path(args[[1]], "packages/r"), quiet = TRUE) source(args[[4]]) prepared <- read_source(args[[2]]) values <- cbind(prepared$X, y = prepared$y) restored <- read.csv( args[[3]], check.names = FALSE, colClasses = c("character"...
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R
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#!/usr/bin/env Rscript args = commandArgs(trailingOnly=TRUE) if (length(args)!=2) { stop("Two argument must be supplied", call.=FALSE) } raw_counts_path = args[1] output_dir = args[2] library(DESeq2) library(data.table) raw_counts <- read.table(raw_counts_path, sep = "\t", header = T, st...
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R
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test_that("CSCORE_IRLS Rcpp version matches base version on a simulated independent gene pair", { expect_equal(CSCORE_IRLS_cpp(ind_gene_pair$counts, ind_gene_pair$seq_depths, IRLS_par = list(n_iter = 10, eps = 0.05, verbose = FALSE, conv = 'max')), CSCORE_IRLS_base(ind_ge...
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R
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# Libraries install.packages('heatmaply') library(heatmaply) # Load data Antero <- read.csv("..path to your folder here\\Figure 1 -Source data.csv",sep=",") row.names(Antero)<- Antero$Nucleus Antero<-Antero[1:118,1:6] Antero<-Antero[order(Antero$Mouse.1),] Antero_matrix<-data.matrix(Antero) # cluster rows ...
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R
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#!/usr/bin/env Rscript args = commandArgs(trailingOnly=TRUE) if (length(args)!=2) { stop("Two argument must be supplied", call.=FALSE) } dataset_path = args[1] output_dir = args[2] library(ggplot2) dataset <- read.table(dataset_path, sep = "\t", header=T, stringsAsFactors = F) samples <- dataset$sample dataset_cou...
c46ff5318d798eda1555df8e9282842e5cbc38da925a3d9ccd9ac5106c25957b
R
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.new_registry <- function( release, index_sha256, index_url, schema_version = 1L ) { structure( list( release = release, index_sha256 = index_sha256, index_url = index_url, schema_version = schema_version ), class = "datamonger_registry" ) } print.datamonger_registry <- ...
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R
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35
#' @name getDist #' @title Get tissue specific distribution #' @description #' This function counts the total number of tissue specific protein coding, #' lincRNA, and miRNA genes for each tissue. #' @param x ensembl annotated tau expression fraction file #' i.e. output from getMart() #' @param y threshold tau value...
b599e9ed541477ddf0d7a9326d8c70a741fc3e1b19786800e7814ffe4112aa51
R
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#!/usr/bin/env Rscript # module load R/4.0.2 library(genefu) args<-commandArgs(TRUE) annotation <- read.delim(as.matrix(args[1], header=T, sep='\t')) rnaseq <- read.delim(as.matrix(args[2], header=T, sep='\t')) # Prepare TPM input: n <- rnaseq$probe rnaseq_t <- as.data.frame(t(rnaseq[,-1])) colnames(rnaseq_t) <- n...
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R
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# sample n rows from data sample_rows <- function(x, n) { if (nrow(x) > n) { x[sample(seq_nrow(x), n), ] } else { x } } # sample n cols from data sample_cols <- function(x, n) { if (ncol(x) > n) { x[, sample(seq_ncol(x), n)] } else { x } } #' Sample cells from a...
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R
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read_source <- function(path) { lines <- readLines(gzfile(path), warn = FALSE) start <- match("!series_matrix_table_begin", lines) end <- match("!series_matrix_table_end", lines) stopifnot(!is.na(start), !is.na(end), start < end) values <- read.delim( textConnection(lines[seq.int(start + 1L, end - 1L)]), ...
d5166993703475d0028bf6cd7f83758bb9924693d13b1365e18296d1aafd0ead
R
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# start all statistical analyses from here in order to avoid loading the data # several times over and also in order to keep an overview of the current pipeline # of statistical analysis. All packages needed should also be loaded here # --- Preparation ----------------------------------------------------------- # g...
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R
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#!/usr/bin/env Rscript library(ggplot2) args = commandArgs(trailingOnly=TRUE) if (length(args)!=4) { stop("Four argument must be supplied", call.=FALSE) } expression_norm_path = args[1] output_dir = args[2] samples_percentage = as.numeric(args[3]) # default 0.2, minimum percentage of samples, a miRNA has to be expre...
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R
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#' Combine all DESeq2 results into a single #' excel file. # req'd libs x <- c("magrittr", "tidyverse", "openxlsx", "data.table") sapply(x, library, character.only = T) source("./functions/remove_redundancy.R") # load deseq files all <- list.files("./adj_data/deseq/filtered/", full.names = T) # remove unncessary it...
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R
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library(plotly) df <- read.csv("./CMOT_Final/PBMC/Cell_TruevsPred_22642.csv") scaleFUN <- function(x) format(x,scientific = TRUE, digits=3) #df$Name <- c('CD3','CD4','CD8a','CD14','CD15','CD16','CD56','CD19','CD25','CD45RA','CD45RO','PD','TIGIT','CD127') p<-ggplot(df, aes(x = TrueGE, y = PredictedGE )) +geom_point(c...
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R
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#' Run Rsubread to obtain count data for re-running DESeq2 for #' filtered MeDIP-Seq peaks - run this on linux ec2 for RAM > 16 cores. # req'd pkgs # NOTE: To run Rsubread for indexing of genome, # alignment and counting, you need to run on a # machine w/ > 16 GB RAM x <- c("openxlsx", "magrittr", "tidyverse", ...
ff1379ad284467900febfd1a7ae2432597d42cf904926abd7cdbfa53fdd8d6e7
R
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#' @name getTissue #' @title Get expression and specificity of each gene in a single tissue #' @description #' This function takes a user defined tissue and extracts the ensembl #' annotations, normalised expression values, tau values, and tau expression #' fractions of all genes in that tissue. Each gene's score is...
c2674420fe0caf9c555f057ade21a6bd2e65aeb45e859138e4c5e09450135dc6
R
1,469
53
df = read.csv("../data/subjective_dbs_ranking.csv", header = TRUE) df$best = as.character(df$best) df$best[df$best == "100"] = "100%" df$best[df$best == "33"] = "33%" df$best[df$best == "66"] = "66%" df$best[df$best == "130"] = "130Hz" df$best[df$best == "85"] = "85Hz" df$best[df$best == "30"] = "30Hz" df$best...
99f306fd01ab09e89b3c71df485b71116cc2beca20df74abd598af17aaeee14d
R
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# comparing neff predicted vs. neff natural accors different alignments similarities. # reading csv files natural_var <- read.csv(file="./stats_align_all.csv", header=TRUE, sep=",") natural_var_20 <- read.csv(file = "./stats_align_files/stats_align_20.csv", header=TRUE, sep=",") natural_var_40 <- read.csv(file = "./s...
677cc61ae9e13679fa1f07832d329b2184dd1df73b1588f2c7f5fe974f589a4b
R
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#' Split combined pipeline step #' #' Some methods perform multiple steps of a pipeline. This function assists with #' splitting the combined pipeline step into multiple steps with duplicated #' method names. #' #' @param x a results data.frame from `apply_methods()`. #' @param step the name of the column to split. #' ...
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R
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#!/usr/bin/env Rscript args = commandArgs(trailingOnly=TRUE) if (length(args)!=5) { stop("Six arguments must be supplied", call.=FALSE) } expression_norm_path = args[1] samples <- read.table(file = args[2], sep = "\t", header = T)[,"sample"] # get samples from samplesheet output_dir = args[3] samples_percentage = a...
eea7acceae9d5d9b433282b2ee6b839446df29019d78f002f8006f3c5c7c46c5
R
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library(uwot) library(RSpectra) context("Spectral") test_that("1 dimensional output gives a matrix", { expect_ok_matrix(spectral_init(V_union, ndim = 1, verbose = FALSE), nc = 1) expect_ok_matrix(normalized_laplacian_init(V_union, ndim = 1, verbose = FALSE ), nc = 1) expect_ok_matrix(laplacian_eigenmap...
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R
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--- title: "Stride_Selection" author: "Brett Hale" date: "8/17/2022" output: html_document --- ```{r} library(dbplyr) library(dplyr) library(devtools) library(ggplot2) library(viridis) ``` ```{r} Stride <- read.csv("/Volumes/USB20FD/PhD Research/Chapter_2/Stride.csv") Stride$Stride <- as.character(Stride$Stride) ...
e5a7b26a41d07a37d35bd5a351369cbe57cae750506e964b0f221740577c98ad
R
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# library library(ggplot2) library(plotly) library(dplyr) library(hrbrthemes) p<- read.csv("./LiuCancer_RNA_TO_ATAC_Correlations_10000genes_BinNorm_60_40_split_2.csv") #p$Method <- factor(p$Method, levels = c('CMOT(p=25%)', 'CMOT(p=50%)', 'CMOT(p=75%)','CMOT(p=100%)', 'MOFA+', 'Seurat', 'TotalVI')) p$Method <- facto...
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R
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#!/usr/bin/env Rscript # module load R/4.0.2 # Use arguments: args<-commandArgs(TRUE) library("dplyr") library("ggpubr") library(PairedData) t <- read.table(args[1], sep="\t", header=FALSE) ref <- t$V1 other <- t$V2 my_data <- data.frame(group = rep(c(args[2], args[3]), each = 8), tsi = c(ref, other)) group_by(m...
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R
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--- title: "Checking SZ Pipeline outputs" output: html_document: keep_md: TRUE toc: TRUE --- ## gonna check that our subject list don't inlude any missing data ```{r} library(tidyverse) ``` ```{r} ## we created a list of files that are super short after censoring.. number_tr1 <- read_table2("../data/data/...
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R
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#' @name check_class #' @title Check class of object #' @description Check an object against a vector of class names. Testing if they #' match any or all of the classes. For is_all_of, the object needs to be at #' least every class specified, but it can have addition classes and still #' pass the check. #' #' @pa...
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R
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--- title: "CellBench User's Guide" author: "Shian Su" date: "`r Sys.Date()`" output: BiocStyle::pdf_document vignette: > %\VignetteIndexEntry{Vignette Title} %\VignetteEngine{knitr::rmarkdown} %\VignetteEncoding{UTF-8} --- ```{r setup, include=FALSE} knitr::opts_chunk$set(echo = TRUE) ``` ```{r} library(CellBe...
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R
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#' @name plotDensity #' @title Plot tissue specificity distribution #' @description #' This function plots the tau value of every gene to see which tau values #' occur most often #' @param x data frame of annotated tissue specificity (tau) values #' i.e. output from getMart() #' @return #' Returns a tissue specific...
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R
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rspectra_is_installed <- function() { is_installed("RSpectra") } rspectra_eigs_asym <- function(L, ndim) { res <- NULL suppressWarnings(res <- tryCatch( RSpectra::eigs( L, k = ndim + 1, which = "LR", opts = list(tol = 1e-4) ), error = function(c) { NULL } )) res ...
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R
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dvs = c("gait_speed_meter_per_second", "stride_length_cm", "max_sensor_lift_cm") #dvs = c("gait_speed_meter_per_second") plot_model <- function(dvname, save = FALSE){ # define y axis label if(dv == "gait_speed_meter_per_second") ylab = "gait speed (m/s)" if(dv == "stride_length_cm") ylab = "stri...
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R
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#' Summary of benchmark_tbl #' #' @param object the benchmark_tbl to be summarised #' @param ... additional arguments affecting the summary produced. #' #' @return None #' #' @export #' @keywords internal #' #' @examples #' # list of data #' datasets <- list( #' set1 = rnorm(500, mean = 2, sd = 1), #' set2 = rn...
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R
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#!/usr/bin/env Rscript args = commandArgs(trailingOnly=TRUE) if (length(args)!=3) { stop("Three argument must be supplied", call.=FALSE) } expression_raw_path = args[1] samplesheet <- read.table(file = args[2], header = T) # get samples from samplesheet samples <- samplesheet$sample output_dir = args[3] suppressW...
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R
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--- title: "ImputeBenchmark" author: "Shian Su" date: "08/11/2018" output: html_document --- ```{r setup, include=FALSE} library(CellBench) library(dplyr) library(ggplot2) library(purrr) knitr::opts_chunk$set(echo = TRUE) ``` ```{r} CellBench:::load_mrna_mix_data() set_cellbench_threads(4) data <- list( mrna_mi...
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R
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library(uwot) context("knn affinity") expected_sparse <- matrix(0, nrow = 10, ncol = 10) for (i in seq_len(nrow(nn$idx))) { for (j in seq_len(ncol(nn$idx))) { expected_sparse[i, nn$idx[i, j]] <- 2 } } expected_sparse <- Matrix::drop0(expected_sparse) res <- nng_to_sparse(nn$idx, val = 2) expect_equal(res, exp...
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R
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df = read.csv("../data/subjective_dbs_ranking.csv", header = TRUE) df$best = as.character(df$best) df$best[df$best == "100"] = "100%" df$best[df$best == "33"] = "33%" df$best[df$best == "66"] = "66%" df$best[df$best == "130"] = "130Hz" df$best[df$best == "85"] = "85Hz" df$best[df$best == "30"] = "30Hz" df$best...
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R
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#' @name checkInput #' @title Checks the input data frame for incompatible values #' values, and infinite values #' @description #' The input dataframe contains expression data so each cell should contain only #' non-negative, non-infinite, numerical characters (>=0). This function #' identifies if the dataframe con...
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R
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library(data.table) library(readxl) library(stringr) setwd('/Volumes/ncatssctl/NGS_related/BulkRNA/ISB009') files <- as.data.table(readxl::read_xlsx('/Volumes/ncatssctl/NGS_related/Sample Sheet/BulkRNA/ISB009_Library_prep_sample_sheet.xlsx', sheet=2)) files[,shortfile := tstrsplit(Sample, '_L')[1]] files dir <- '/d...
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R
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# code was adapted from: https://github.com/Noble-Lab/Polarbear library(data.table) library(readxl) library(ROCR) library(Matrix) library(scran) library(ggplot2) library(ggallin) df <- read.csv("./GeneWiseCorrelations.csv") #columns: methods, rows: inferred vs measured correlation of a gene #colnames(df)[2]<- "Polar...
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.canonical_bytes <- function(components) { .native_result(dm_canonical(components, FALSE)) } .canonical_sha256 <- function(components) { .native_result(dm_canonical(components, TRUE)) } .descriptor_value <- function(value) { if (.is_scalar_character(value)) { if (identical(value, "-zero")) { return(-0...
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args <- commandArgs(trailingOnly = TRUE) stopifnot(length(args) == 7L) pkgload::load_all(file.path(args[[1]], "packages/r"), quiet = TRUE) source(args[[6]]) prepared <- read_source(args[[2]], args[[3]], args[[4]]) numeric_values <- cbind(prepared$X, y = prepared$y) metadata <- data.frame( sample_id = prepared$sample_...
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R
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library(uwot) context("Scaling") iris10_sd <- apply(iris10, 2, sd) iris10_mean <- apply(iris10, 2, mean) iris10_none <- scale_input(iris10, scale_type = FALSE) expect_equal(apply(iris10_none, 2, sd), iris10_sd) expect_equal(apply(iris10_none, 2, mean), iris10_mean) iris10_scale <- scale_input(iris10, scale_type = TR...
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R
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#' @name calcTau #' @title Implements tissue specificity algorithm #' @description #' This function first places all quantile normalised values into decile bins. #' For each gene, it then uses the bin profile (row of bin values) to calculate #' a single tau value between 0 (non-specific) and 1 (absolutely specific)....
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R
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--- title: "t-UMAP" resource_files: - img/tumap/umap.png - img/tumap/tumap.png --- ```{r, include = FALSE} knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) ``` If you choose the UMAP curve parameters to be `a = 1` and `b = 1`, you get back the Cauchy distribution used in [t-Distributed Stochastic Neig...
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#' @name getControls #' @title Get a set of genes that can be used to differentiate between 2 tissues #' @description #' This function selects 2 lists of genes, 1 for each tissue. Each list includes #' genes that are highly specific and expressed in one tissue with <0.1 #' quantile normalised expression in the other....
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R
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#' Create a cached function for CellBench #' #' Take a function and return a cached version. The arguments and results of a #' cached method is saved to disk and if the cached function is called again #' with the same arguments then the results will be retrieved from the cache #' rather than be recomputed. #' #' \bold{...
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R
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dvs = c("gait_speed_meter_per_second", "stride_length_cm", "max_sensor_lift_cm") #tests = c("fast", "normal", "slow", "tug", "gait") # Use these for the additional analysis of the "free" condition #dvs = c("max_sensor_lift_cm") #tests = c("free") lme_model <- function(dvname, save = FALSE, padj = "fdr"){ modelform...
36a1442c1c1776692148bedbbac6393a7ac6ce8738dcd359bbc77173621fc5b1
R
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#!/usr/bin/env Rscript library(Biostrings) library(argparser) args <- commandArgs(trailingOnly = TRUE) parser <- arg_parser("Argument parser for circRNA quantification", name = "quant_parser") parser <- add_argument(parser, "--index", help = "Psirc index file name/file location", default = "psirc.index") parser <- a...
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R
1,880
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.error_classes <- c( "unknown-dataset" = "datamonger_unknown_dataset", "unsupported-registry" = "datamonger_unsupported_registry", "unsupported-decoder" = "datamonger_unsupported_decoder", "artifact-unavailable" = "datamonger_artifact_unavailable", "artifact-offline" = "datamonger_artifact_offline", "retrie...
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R
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# remove "OFF" from dbsconditions dbsconds = unique(df$dbscond)[!unique(df$dbscond) %in% "OFF"] npcs = 10 # number of principal components to use dopca = TRUE verb = TRUE # define svm model model <- function(cond){ msg("Prediction for", cond, verbose = verb) ddf = df[complete.cases(df) & df$dbscond == cond,] n ...
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R
1,903
48
test_that("Correct dimension", { test_dat = readRDS("fixtures/mic_highly_expressed_500_AD_control") count = test_dat[[1]] seq_depth = test_dat[[2]] CSCORE_result = CSCORE_IRLS(X = count, seq_depth = seq_depth) rho = CSCORE_result$est pvalues = CSCORE_result$p_value test_stats = CSCORE_result$test_stat p...
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library(uwot) context("PCA") iris10prcomp <- prcomp(iris10, retx = TRUE, center = TRUE, scale. = FALSE) test_that("PCA initialization", { iris10_pca_scores <- pca_init(iris10, ndim = 2) suppressWarnings(iris10_irlba_scores <- irlba_scores(iris10, ncol = 2)) expect_equal(abs(iris10prcomp$x[, 1:2]), abs(iris10_p...
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R
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#!/usr/bin/env Rscript if(!require(pacman)) install.packages("pacman", repos = "http://cran.us.r-project.org") pacman::p_load(BSgenome, Biostrings, GenomicRanges, GenomicFeatures, seqinr, rtracklayer) overlap <- function(exons, circRNAs) { # find all exons within the circRNAs and reformat result o <- findOverlap...
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R
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#load libraries library(magrittr) library(tidyverse) #CONSTANTS #set a constant to attach to file names outfileBase <- "03_NCATS_ATAC_" #set a common theme for plotting mytheme <- theme(plot.title = element_text(lineheight = 0.8, size = 20, family = "NotoSans-Bold"), axis.text = element_text(size = ...
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#' Create manhattan plots for targeted genes: #' elf5, dlk1, ube3a, igf2, #' zfat, cdkn1c, proser2-as1 #' These are the only ones left of the 11 # req'd pkgs x <- c("ggplot2", "tidyverse", "qqman", "data.table", "ggrepel", "gtools") sapply(x, library, character.only = TRUE) source("./functions/build_manhattan....
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R
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.new_int64 <- function(values, valid = !is.na(values)) { values[!valid] <- NA_character_ structure(values, class = c("datamonger_int64", "character")) } .parse_binary64 <- function(value) { result <- dm_parse_binary64(value) if (is.null(result$category)) result$value else NULL } format.datamonger_int64 <- fun...
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R
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trimExpression = function(expr,n.genes) { m = apply(expr,2,function(x) { n = min(n.genes,sum(x>0)) A = sample(which(x>0),n) y = matrix(0,length(x)) y[A] = x[A] y }) rownames(m) = rownames(expr) colnames(m) = colnames(expr) m } summarySE <- function(data=NULL, measurevar, groupvars=NULL,...
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--- title: "Visualize the result of simulation experiment" output: rmarkdown::github_document --- ```{r} library(tidyverse) library(ggsci) library(ggpubr) theme_pwas = theme_pubclean(base_size = 7,base_family = "Helvetica") p_list=list() attribute_name ="n_vertex" p_list[[attribute_name]]=lapply(paste0("../results/si...
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R
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test_that("Windows release builds keep Cargo objects outside the install path", { config <- test_path("..", "..", "tools", "config.R") skip_if_not(file.exists(config), "Configuration is tested from the source tree.") config <- normalizePath(config, winslash = "/") package <- normalizePath(test_path("..", ".."),...
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R
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library(uwot) context("rnndescent integration") test_that("rnndescent accepts integer-valued doubles from uwot", { testthat::skip_if_not_installed("rnndescent") model <- umap( iris10, n_neighbors = 4, nn_method = "nndescent", nn_args = list( n_trees = 2, leaf_size = 5, max_tree_d...
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R
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library(tidyverse) library(cowplot) library(ggforce) #getting the average % homology for all proteins in the alignment. homol_data <- read.csv(file = "./output/output_PSICOV/percent_homol.csv", header=TRUE, sep=",") plot_a <- homol_data %>% ggplot(aes(x = percent_homol)) + geom_density(fill = "seashell3", color =...
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R
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read_source <- function(directory) { paths <- list.files(directory, pattern = "^TCGA-.*[.]txt$", full.names = TRUE) sample_ids <- sub("[.]txt$", "", basename(paths)) stopifnot(length(paths) == 606L, !anyDuplicated(sample_ids)) # TCGA sample types 01 and 06 identify primary and metastatic tumors. keep <- subst...
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R
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--- title: "SZ Location Stats" output: pdf_document: default html_notebook: default --- ```{r} library(dplyr) library(tidyr) library(broom) library(knitr) library(igraph) library(ggplot2) library(readr) library(stringr) ``` ```{r} # Number of subjects # 258 SCZ, 225 HC # PINT distances qced_sublist <- read_csv(...
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R
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#' @name plotDist #' @title Plot number of tissue specific genes per tissue #' @description #' This function plots the number of absolutely specific genes (ASGs, tau = 1) #' alongside the number of highly specific genes (HSGs, tau >=0.85) in #' each tissue #' @param x ensembl annotated tau expression fraction file #...
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# Configure R package builds to use sccache. # # Pass --cmake to configure CMake launchers instead,to avoid selecting an sccache-wrapped # CXX as NVCC's host compiler. args <- commandArgs(trailingOnly = TRUE) if (length(args) > 1L || (length(args) == 1L && args[[1L]] != "--cmake")) { stop("Usage: setup_r_sccache.R [...
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R
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test_that("preprocessing metadata follows the shared contract without changing data", { cache_dir <- tempfile("datamonger-preprocessing-") seeded <- seed_conformance_cache(cache_dir) cases <- read_fixture_json("conformance", "preprocessing.json")$cases baseline <- fetch_data("conformance:mixed_csv@1", registry ...
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R
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test_that("The covaiates' effect sizes are computed correctly", { set.seed(202212) n <- 6000 sim_seq_depths <- exp(rnorm(n, 7.3, sd=0.6)) sim_seq_depths <- sim_seq_depths[!sim_seq_depths < 400] sim_seq_depths <- round(sim_seq_depths) n <- length(sim_seq_depths) mu <- 4.83 * 7.56e-05 # extracted from a sp...
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R
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--- title: "20220618_coseq" author: "Asela Wijeratne" date: '2022-06-18' output: html_document --- ```{r setup, include=FALSE} library(coseq) library(Biobase) library(corrplot) ``` ```{r} ###entire normalized expression matrix corrected_data <- read.csv("20220304_corrected_data.csv", row.names = "X") DE_DEseq_nor...
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R
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fixture_path <- function(...) { testthat::test_path("fixtures", ...) } read_fixture_json <- function(...) { jsonlite::fromJSON( fixture_path(...), simplifyVector = FALSE, bigint_as_char = TRUE ) } dm_internal <- function(name) { getFromNamespace(name, "datamonger") } write_bytes <- function(conte...
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R
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#' simulated single cell multi-omics data. #' #' A dataset containing paired single-cell RNA-seq and ATAC-seq data as well as the true labels of cell groups #' #' @format A list contains two field data: #' \describe{ #' \item{data}{Simulated single-cell RNA-seq and ATAC-seq data} #' \item{labels}{The true labels of...
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R
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log <- file(snakemake@log[[1]], open = "wt") sink(log) sink(log, type = "message") message("CONFIGURATION STEP") # A. Parameters: # 1. Load libraries. suppressMessages(library("Seurat")) suppressMessages(library("dplyr")) suppressMessages(library("data.table")) suppressMessages(library("reticulate")) suppressMessage...
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R
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library(uwot) context("optimization only") # this mainly exists to hedge against rhub timing out during tests and to still # exercise the main umap code even with RSpectra and other dependencies # temporarily removed due to excessive compilation times. Filter on # this in testthat.R: # # test_check("uwot", filter = "o...
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R
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#' A simulated independent gene pair #' #' This data set is created only for illustrative purposes and is used to test CSCORE_IRLS.R. #' The source code for generating this data set is in data-raw/ on Github. #' #' @format ## `ind_gene_pair` #' A list with 2 elements: #' \describe{ #' \item{counts}{A 1972 by 2 count ...
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R
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#' @name getMart #' @title Get ensembl annotations #' @description #' Connects to ensembl archive to get id, name and type for every gene #' @param x species: 'human', 'macaque', or 'mouse' #' @param y ensembl archive version: 79..90 #' @param z output from calcTau() #' @return #' Returns a dataframe containing tau val...
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R
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library(data.table) library(ggplot2) library(Hmisc) library(DESeq2) load("/Volumes/ncatssctl/NGS_related/BulkRNA/ISB025/ISB025_Vukasin/Analysis/Vukasin.DDS.RData") dds.subset <- dds[ , dds$condition %nin% c("NCRM5_astro_D4", "NCRM5_astro_D7","NCRM5_astro_D14", ...
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R
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source("http://webstimate.org/twolines/twolines.R") library(tidyverse) library(scales) #load data #friendship friend <- read.csv('friend_baseline.csv') #mental health mh <- read.csv('cbcl_baseline.csv') #cognition cog <- read.csv('tbss_baseline.csv') #covariates covs <- read.csv('cov_beh_baseline.csv') ...
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R
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packages <- c("ggplot2", "reshape2", "dplyr") for(i in 1:NROW(packages)){ if(!require(packages[i], character.only = TRUE)){ install.packages(packages[i]) library(packages[i], character.only = TRUE) } } model <- "U256" dir_parent <- "/home/manuel/Dropbox/tmp" dir_sub <- "cpts/trained_mod" filename <- "hist...
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.validate_libsvm_options <- function(options) { .require_exact_fields( options, c( "index_base", "feature_count", "duplicate_features", "label_type", "row_order", "target_name" ), "LIBSVM options", "datamonger_unsupported_decoder" ) if ( !identical(opti...
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test_that("fetch_data verifies native results without serializing them in R", { cache_dir <- tempfile("datamonger-native-") on.exit(unlink(cache_dir, recursive = TRUE), add = TRUE) seeded <- seed_conformance_cache(cache_dir) cases <- read_fixture_json("conformance", "cases.json")$cases testthat::with_mocked_b...
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R
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#' @name plotGene #' @title Plot specificity of a user defined gene for each tissue #' @description #' This function takes a user defined gene (case sensitive) and plots the #' tau expression fraction of that gene in each tissue. This allows the user #' to visualize the tissue/tissues in which the genes has relativel...
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R
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#this code is a continuation of figure 4 #correlation coefficients of wt prob predicted by CNN as a function of #neff in the alignment. library(tidyverse) library(cowplot) library(sinaplot) library(ggforce) # reading csv files natural_var <- read.csv(file="./stats_align_all.csv", header=TRUE, sep=",") natural_var_20...
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R
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--- title: "Figure_5" author: "Brett Hale" date: "8/22/2022" output: html_document --- ```{r} library(dbplyr) library(dplyr) library(devtools) library(ggplot2) ``` ```{r} ##Plot AT model generalization accuracies cross_species_facet <- read.csv("/Volumes/USB20FD/PhD Research/Chapter_2/cross_species_facet.csv") c...
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R
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############################################# ##### Set directories ############################################# if(Sys.info()['sysname'] == "Windows"){ # paths Win wd <- "C:/Users/Manuel/Nextcloud/Masterarbeit/" }else if(Sys.info()['sysname'] == "Linux"){ # paths Lin wd <- "/home/manuel/Nextcloud/Masterarbeit...
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.preprocessing_metadata <- function(dataset) { if (!("preprocessing" %in% names(dataset))) { return(NULL) } fail <- function(message) .abort_category("unsupported-registry", message) nonempty <- function(value, field) { text <- .require_string(value, field) if (!nzchar(text)) fail(paste0(field, " mu...
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library(tidyverse) library(yardstick) library(ggpubr) library(cowplot) library(sqldf) library(sinaplot) library(dplyr) library(ggforce) # reading csv files natural_var <- read.csv(file="./stats_align_all.csv", header=TRUE, sep=",") cnn_var <- read.csv(file="./stats_cnn.csv", header=TRUE, sep=",") # joining the two da...
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--- title: "Optional Dependencies" --- ```{r, include = FALSE} knitr::opts_chunk$set( collapse = TRUE, comment = "#>", eval = FALSE ) ``` There are a variety of packages that `uwot` will make use of if you install them (and load them), but that you don't *need* so are optional. These include: * [RcppHNSW](http...
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#!/usr/bin/env Rscript # Command line argument processing args <- commandArgs(trailingOnly=TRUE) if (length(args) < 3) { stop("Usage: edgeR_heatmap_MDS.r <sample_1.bam> <sample_2.bam> <sample_3.bam> (more bam files optional)", call.=FALSE) } # Load / install required packages if (!require("limma")){ source("ht...
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hnsw_nn <- function(X, k = 10, metric = "euclidean", M = 16, ef_construction = 200, ef = 10, n_threads = NULL, n_build_threads = NULL, ret_index = FALSE, ...
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#' Create a list of functions with arguments varying over a sequence #' #' Generate a list of functions where specific arguments have been pre-applied #' from a sequences of arguments, i.e. a function f(x, n) may have the 'n' #' argument pre-applied with specific values to obtain functions f1(x, n = 1) #' and f2(x, n =...
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# Function to plot relevance layer boxplots relevance.boxplots <- function(plot.df){ curr.boxplot <- plot.df %>% mutate( GROUPS = fct_relevel(GROUPS, 'Top', 'Middle', 'Bottom'), BaseToken = fct_reorder(BaseToken, median) ) %>% ggplot(aes(y = BaseToken,fill=Type)) + geom_boxplot(aes(xmin=m...
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#' Strip timing information #' #' Takes the result of a time_methods() call and remove timing information from #' the `timed_result` column, replacing it with a `result` column and converting #' it to a benchmark_tbl. #' #' @param x the benchmark_timing_tbl object #' #' @return benchmark_tbl #' #' @seealso \code{\link{...
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personal_rust <- path.expand("~/.cargo/bin") if (dir.exists(personal_rust)) { Sys.setenv(PATH = paste(Sys.getenv("PATH"), personal_rust, sep = .Platform$path.sep)) } cargo <- Sys.getenv("DM_CORE_CARGO", unset = Sys.getenv("CARGO", unset = Sys.which("cargo"))) rustc <- Sys.getenv("DM_CORE_RUST...
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#' Set number of threads used by CellBench #' #' Sets global parameter for CellBench to use multiple threads for applying #' methods. If any methods applied are multi-threaded then it's recommended to #' set CellBench threads to 1. It only recommended to use CellBench with #' multiple threads if methods applied can be ...
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############################################# ##### Load packages, set theme ############################################# packages <- c("readxl", "ggplot2", "dplyr", "reshape2") for(i in 1:NROW(packages)){ if(!require(packages[i], character.only = TRUE)){ install.packages(packages[i]) library(packages...
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library(harmony) library(Seurat) library(biomaRt) library(ggrepel) setwd("~/Desktop/scRNA-seq_analysis/matrices") # load seurat objects and annotate genes for FADS-sorted samples obj <- readRDS('B_cell.dgecounts.rds') matrix <- as.matrix(obj$umicount$inex$all) annot <- getBM(attributes = c('external_gene_name','gene_...
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### This script plot global cortical thickness values across age ranges ### Written and modified by Christina Stier, 2021/2022 ### R version 3.6.3 (2020-02-29) ### RStudio 2021.09.0+351 "Ghost Orchid" Release (077589bcad3467ae79f318afe8641a1899a51606, 2021-09-20) for macOS ### Mozilla/5.0 (Macintosh; Intel Mac OS X 10...
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#!/usr/bin/env Rscript library(data.table) args = commandArgs(trailingOnly=TRUE) if (length(args)!=2) { stop("Two argument must be supplied", call.=FALSE) } dataset_path = args[1] input_dir = args[2] output_dir = "./" dataset <- read.table(dataset_path, sep = "\t", header = T, stringsAsFactors = F) samples <- data...
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library(uwot) context("mixed distance calculations") set.seed(1337) res <- umap(iris10, n_neighbors = 4, n_epochs = 2, init = "spca", verbose = FALSE, n_threads = 0 ) expect_ok_matrix(res) set.seed(1337) resmli <- umap(iris10, n_neighbors = 4, n_epochs = 2, init = "spca", metric = list("euclidean" = 1:4), v...