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It is a Herculean task to try to capture the essence of the writer, doctor and global activist Nawal El Saadawi. There is so much to say, the little things and the bigger things, and at the same time they are still not the same as Nawal. The author of more than fifty books died on March 21, 2021 at the age of eighty-nine.
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My first direct contact with Nawal El Saadawi was on March 14, 2007, and I have kept the first email she sent me. Your yahoo.com email address has been floating in my inbox many times over the course of our friendship. I made a folder in my inbox just for her. Despite not being a typist, Nawal could fire an email faster than a court stenographer. She tapped the keys with her two index fingers as if providing a poignant point. I could see her brain working as she typed.
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I met her on April 16, 2007 at the Springfield, Missouri airport. She was then seventy-five years old. She had been invited to give a series of lectures on creativity and dissidence at Missouri State University. Her thick mane of curly, shockingly white hair that was cut just above her neck, her smooth brown skin and her petite stature did not match the image of the fire blight I had made up in my head. Her walk was purposeful in her brown running shoes. She looked straight at me as she approached. Her eyes sparkled and her smile warmed; "Hello, I'm Nawal," she said in a melodious, conscious and strong voice. What I remember best about Nawal are her eyes, her steadfast gaze. She wasn't afraid.
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What I remember best about Nawal are her eyes, her steadfast gaze. She wasn't afraid.
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She once said to me: "People don't like my politics." She was jailed in 1981 with a group of liberals charged with conspiracy to overthrow Anwar Sadat's regime. After her release, she told Hosni Mubarak that she would sue him for unjustified detention. Her name appeared on a fundamentalist death list that forced her to leave Egypt in the early 20th century. In 2001, an Egyptian attorney filed a civil lawsuit seeking to forcibly separate her from her husband, Sherif Hatata, in response to reports that she was calling the annual pilgrimage to Mecca a pagan practice. She wrote an article in support of the position of her daughter Mona Helmi's (2007) article suggesting naming children after the maternal, not just paternal, line. In 2008 she was accused of rubbish and her books were banned in Egypt. She was accused of offending Islam in her play God resigns at the summit. One of the most amusing anecdotes she shared was her application for president. Of course, she said, she knew she wasn't going to win, but she felt compelled to put her name in the pot. In 2004 she announced her plan for the Egyptian presidential elections in 2005, which Egyptian clergy objected to. Her response to the clergy who opposed women serving as president of the state:
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Because of her physiological characteristics and because of the suffering she experiences during her period. Period? God the University, did menstruation keep Margaret Thatcher from becoming Prime Minister? Does her period prevent an Egyptian woman from working in the field, just like men do from sunrise to sunset? Because pregnancy and childbirth do not stop the women who work in the fields, in the offices and in the embassies. It's funny that these clergymen mention "menstruation" because every woman in politics or in the presidential campaign here is over fifty years old. So what's the problem with menstruation?
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She also had a pungent sense of humor. She once told me how she loved India. She had traveled there with then-husband Sherif Hatata for a conference. She said she loved the Indians and their food. She even expressed some kind of spiritual kinship with them. One night she and her husband returned to their hotel after dinner. She said a man asked him to speak privately. She could hear the man offer to get him a girl, any kind of girl he wanted. After apologizing from the man, Nawal said she approached the man and asked, "What about me? Do you have a girl for me "The man responded by scurrying away. The incident echoes a scene in her play God resigns at the summit (2012), in which the daughter of God challenges him: "Why only recognize male children?"
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Nawal had an institution for languages. She spoke English, French and spoke Italian. However, she only wrote in Arabic and called it the most beautiful language in the world. Once at a conference in Stockholm she pretended not to speak English well and asked the audience to direct their questions to me – as if I could translate them into Arabic – which I couldn't. Months later, I found out. She trusted me to rephrase the questions with a clear indication of the questioner's intent. Since she was familiar with my voice and my thought patterns at this point, she probably trusted me. Nawal didn't trust many people. Men in the government were always suspicious. She called publishers "thieves" and once told me to quit my job. "If I had a boss," she explained, "I would kill him."
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She also had an opinion on everything. At dinner, she remarked: "Americans can take dog bags home with them, in Egypt it is frowned upon." She forever questioned both the practical and philosophical inequalities of her environment. In the case of dog sacks, she spoke to the huge portions served in American restaurants. That said, it wasn't just rhetoric with her. She also referred to professional sport as the "opium of the people". It distracts them from important issues that affect them. "She wasn't a sports fan. However, in 2011 I managed to get her to go to a Morgan State University (American) soccer game with me. She was more impressed with the band than with the game itself.
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After her introduction to the evening event at Missouri State University in 2007, she was standing in front of the audience (not behind a podium) and certainly not sitting in her designated area. "Turn off the lights," she ordered, referring to the spotlight that outlined her shape on the stage. "I want to see who I'm talking to." She began:
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I am African from Egypt, not the Middle East. The Middle East is a term used relative to London to mean that India becomes the Far East. I am not from the third world. There is a world that is a racist, capitalist economy. . . . As a child, I became a feminist when I started asking questions to realize that women are oppressed and feel discriminated against. (April 2007)
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As expected, she had cast a spell over the auditorium of university and community members for the duration of her ninety-minute lecture. She did not speak from notes or give precise lectures. I suspect that her lyrics were derived from what was currently at the forefront of her thoughts. Even when Nawal was tired, she could continue to stand up for her beliefs, as if her words fueled her energy. Her favorite subjects at the time were George Bush "the father" and bin Laden. She referred to them as twins.
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In another conversation she admitted: "If I don't tell the truth, I don't deserve to be called a writer." The statement is immediately reminiscent of the statement she made in her autobiography, ON Daughter of Isis (1995):: "Ever since I had a pen in my fingers, I have fought against history, against the falsification of official registers" (30). She was convinced that "no one sets women free, women set themselves free". She offered this in response to an American politician who said, "We have to help women in the Middle East." In a June 2018 podcast interview with Krishnan Guru-Murthy, she said: "Feminism is not a western invention. Feminism was not invented by American women as many people think. No, feminism is embedded in the culture and struggle of all women around the world. "
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During my more than ten years of acquaintance with her, I traveled with her to London; met her in Sweden; drove her from Atlanta, Georgia to Birmingham, Alabama (when she was the Cosby Chair at Spelman College for two years); arranged for her to attend Morgan State University in Baltimore. It was an amazing gift to have full access to her. I also communicated with her often by email. In the communications, the most common questions I asked her were what she thought of a particular book or article. She was outraged by an article entitled "The Sad State of Arab Men," which appeared in the May 4, 2017 issue of Economist. I sent her a two and a half page reply at a distance on the article to the economist for release. It was not accepted. The response challenged the "scientific research" of "professors who live mainly in the US and Europe and are mostly funded by American and European donors" as one-sided and isolated from real life in the countries they studied.
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My lasting impression of her is this: She would not compromise, and her eyes spoke that truth. Years ago she said to me, "Creativity means disobedience. I am against being careful. Real education means dissatisfaction. Creativity undoes the separation for the self and the "other". It reverses all dichotomies. "Your novels are rich in clues at the sight. In the novel The circling song (1989) the opening line reads: "Every day and at every time when I left the house, my gaze was met by a ring of small bodies that snaked round and round and continuously circled before my eyes" (7). The very last picture I have of her is an internet photo of her surrounded by little boys and girls. She had started a new project to save the world.<eot>The tyrosine kinase pyk2 promotes migration and invasion of glioma cells. - PubMed - NCBI
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1 selected item: 15967096
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Lipinski CA1, Tran NL, Menashi E, Rohl C, Kloss J, Bay RC, Berens ME, Loftus JC.
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Mayo Clinic Scottsdale, Scottsdale, AZ 85259, USA.
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Glioblastoma multiforme is extraordinarily aggressive due to the propensity of cells to migrate away from the tumor core into the surrounding normal brain. In this report, we investigated the role of proline-rich tyrosine kinase 2 (Pyk2) and FAK with regard to influencing glioma cell phenotypes. Expression of Pyk2 stimulated glioma cell migration, whereas expression of FAK inhibited glioma cell migration and stimulated cell cycle progression. Pyk2 autophosphorylation was necessary, but not sufficient, to stimulate cellular migration. The N-terminal domain of Pyk2 is required for stimulation of migration as an N-terminally deleted variant of Pyk2 failed to stimulate migration, whereas expression of an autonomous Pyk2 N-terminal domain inhibited cell migration. Substitution of the C-terminal domain of Pyk2 with the corresponding domain of FAK stimulated cell migration as effectively as wild-type Pyk2; however, substitution of the N-terminal domain of Pyk2 with that of FAK inhibited cell migration, substantiating that the N-terminal domain of Pyk2 was required to stimulate migration. Silencing of Pyk2 expression by RNA interference significantly inhibited glioma migration. Cell migration was restored on re-expression of Pyk2, but expression of FAK in Pyk2 knockdown cells failed to restore migration. We conclude that Pyk2 plays a central role in the migratory behavior of glioblastomas.
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PMC1501165
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Glioma cell migration is stimulated by Pyk2 expression and inhibited by FAK expression. SF767 (A and C) or G112 (B and D) glioma cell lines were infected with recombinant adenoviruses encoding Pyk2 or FAK at the indicated MOI and migration rate on laminin measured with a monolayer migration assay. Migration rates of infected cells were derived from slopes of lines from measurements of radii of cell population versus time. Cells were plated on 1 µg/ml laminin (A and B) or on 10 µg/ml laminin (C and D). Values represent mean ± SD of 10 replicate samples. Expression of Pyk2 or FAK was detected by immunoblotting of cell lysates with anti-FLAG or anti-HA antibodies, respectively. *P < .05.
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Neoplasia. 2005 May;7(5):435-445.
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FAK expression stimulates glioma cell proliferation. Subconfluent cultures of G112 or SF767 cells were infected with varying MOI of the control β-galactosidase, wild-type FAK, or wild-type Pyk2. The percentage of cells in S-phase was determined by flow cytometry 24 hours after infection. (A) Expression of FAK significantly increased the percentage of G112 cells in S-phase in a dose-dependent manner (*P ≤ .01). In contrast, expression of Pyk2 decreased the percentage of cells in S-phase relative to control infected cells (*P < .05). (B) Expression of FAK increased the percentage of SF767 cells in S-phase in a dose-dependent manner (*P < .001). Pyk2 did not alter the percentage of SF767 cell in S-phase compared to the control β-galactosidase-infected cells.
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Stimulation of glioma cell migration by Pyk2 requires the N-terminal domain. (A) SF767 cells were infected with adenoviruses encoding β-galactosidase, wild-type Pyk2, or the indicated Pyk2 variants (MOI = 20). Sixteen hours after infection, cells were seeded onto laminin (1 µg/ml) and migration rate was determined 24 hours postseeding. Values are mean ± SD of 10 replicate samples (*P < .01). (B) Expression of each of the epitope-tagged constructs was detected by blotting cell lysates with anti-Flag or anti-HA antibodies as indicated.
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Silencing of Pyk2 and FAK expression in SF767 glioma cells. SF767 glioma cells were infected with a retrovirus expressing both a GFP tag and an siRNA targeting human Pyk2 or an siRNA targeting FAK. Forty-eight hours after infection, GFP-positive cells were collected by mass sorting on a FACS Vantage flow cytometer. (A) Top panel: Lysates of wild-type SF767 cells or SFPyk2i cells were immunoblotted with antibodies specific for Pyk2 or FAK. Bottom panel: FACS histogram of GFP expression in the mass-sorted cell population. (B) Top panel: Lysates of wild-type SF767 cells or SFFAKi cells were immunoblotted with antibodies specific for Pyk2 or FAK. Bottom panel: FACS histogram of GFP expression in the mass-sorted cell population.
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Reconstitution of Pyk2 expression but not FAK restores glioma cell migration. Wild-type SF767, SFPyk2i, or SFFAKi cells were infected (MOI = 20) with recombinant adenoviruses expressing β-galactosidase, FLAG-tagged Pyk2, or HA-tagged FAK, plated on laminin (1 µg/ml), and migration rates were determined with the radial migration assay. Values represent mean ± SD of 10 replicate samples. Matching aliquots of cells were lysed and lysates were immunoblotted with the indicated antibodies (*P < .01).
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Silencing Pyk2 expression inhibits cell invasion in organotypic brain slice. SF767 cells stably transduced with RFP (left panels) or SFPyk2i cells expressing GFP (right panels) were seeded onto bilateral putamen of organotypic rat brain slice and cultured for 5 days. The extent of cell invasion was measured by optical sectioning by confocal microscopy. Images are at the surface of the slice (top), or at the indicated depths and magnification.<eot>Beijing Love | UF in Beijing Internship: Chinese Commerce & Culture
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← Why am I home again?
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On that teaching status →
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Posted on September 24, 2014 by Jason Ward
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The first week in Beijing has been unforgettable and I've quickly fallen in love with this city. Despite all the culture shock, the one thing that surprises me the most is the sense of community I feel around me even in such a large city like Beijing. I liked walking through the park by the Temple of Heaven and seeing everyone hanging out. It was very peaceful. This week we also went to Tiananmen Square, the Forbidden City, Summer Palace, Beijing Zoo, and of course the Great Wall of China. We also made various business visits to Hyundai Manufacturing, Career International, PR Wire News, the noodle factory and others. This whole week we've had the most amazing tour guide and friend to show us around, Lei. She made the trip even better with her enthusiasm and teaching us all about Beijing.
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My favorite thing so far was going to the Great Wall of China. It was breathtaking, pictures don't do it justice. The best part of the Great Wall was going to the ruins part. It had the best view by far. Despite the pollution, Beijing has some great sightseeing and nature. We've also gotten very lucky and have had multiple days of blue skies!!
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The food is amazing here. I don't think I'll tire of it and I've made it my goal not to have any American food this entire month except on the 4th of July. We've had family style dinners, hot pot, and a beautiful duck dinner. One night we went to a Muslim restaurant and had really good food. Then there was a belly dancing show and singers. I didn't expect to see that in Beijing.
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My one frustration is when it comes to ordering food. The language barrier makes it hard to figure out what I am actually ordering. That has been the only "culture shock" issue I've really had. Besides that everything has been great and I love every second of learning the culture. I've already met some really nice people here at Tsinghua and the visiting students from Hong Kong. My teaching partner is from the U.K and is really cool. I can't wait to start teaching tomorrow!<eot>Nice hotel - Great location for Seattle - Review of The Roosevelt Hotel, Seattle - TripAdvisor
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"Valet Parking a Nightmare"
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Nice hotel - Great location for Seattle - Review of The Roosevelt Hotel
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69 helpful votes "Nice hotel - Great location for Seattle"
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This hotel was was a compromise between location and cost. The location of this hotel meant that we could walk out right into the action of the city without paying too much for a fancy 4-5* hotel. Room was nice - tea and coffee facility was much to be desired. On our last day we were able to leave our bags at the hotel until out late evening departure. Staff were friendly and there is a nice lobby with fireplace.Would a visit again....Yeah I would
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Thank James E Report Ask James E about The Roosevelt Hotel
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I am pleased to read you enjoyed your trip to Seattle and our convenient location. Most importantly, I appreciate your compliments about our service. Thank you for providing us with feedback and mentioning you would stay again!
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Traveller tips help you choose the right room. Room tips (241) 2,223 reviews sorted by:
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Chinese (Traditional) first Danish first Dutch first English first French first German first Italian first Japanese first Korean first Portuguese first Spanish first Any Fred P
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32 helpful votes "So-so Stay"
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We spent the night for a short get-away in our home town. The staff was polite and helpful and the room was large and reasonably comfortable. They also offered free wifi, a welcome service. However, the selection of TV channels was limited and they offered no in-room movies. The most disappointing aspect, however, was the lack of temperature control on the shower. The temperature bounced all over, from scalding to freezing, with no warning.
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Helpful? Thank Fred P Report Ask Fred P about The Roosevelt Hotel
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I appreciate your comments and apologize for the inconvenient issue with your guest room shower. I will share your review with the appropriate management so we may make the necessary improvements. Thank you for your valuable input and we hope you return so we may have the opportunity to restore your affinity for The Roosevelt.
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61 helpful votes "Perfect Location and Comfortable Stay"
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My girlfriend and I stayed this past weekend at The Roosevelt. It was a comfortable stay in the best location in downtown Seattle. Now that we've stayed here, we'll never stay anywhere else when visiting Seattle.I got a good deal off Hotwire and have to admit that some of the reviews on here had me nervous. Yes, the room was a little small and the bathroom a little small, but cmon...breweries, Pike Place, monorail, shopping, restaurants, art museum, Pioneer Square, Bell Town...all of it right outside the hotel within short walking distance. Who's going to stay in the room long enough to feel cramped? If you booked a room in downtown Seattle, then get out there and experience all the fun and excitement! We had absolutely no problem with the size of the room. The beds were soft and comfortable. My girlfriend loved the soft pillows! I'm a pretty light sleeper, yet was able to sleep-in as late as I wanted so the area is quiet enough to get a good sleep. The room, bathroom, hallways and elevators were all clean and tidy. Absolutely nothing to complain about.Check-in was quick and efficient. Jeremy at the front counter was super friendly and was very kind enough to offer some of his favorite Seattle places for visitors. Check-out was just as efficient and we had a cab waiting for upon check out. We used the fitness facility one morning and it small but very functional. We visit Seattle 2-3 times per year and I'm glad to have found our "go-to" hotel. Keep up the great work!
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Thank VanCityChamp Report Ask VanCityChamp about The Roosevelt Hotel
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Thank you for the fantastic review. I am pleased that you enjoyed our location, accommodations and found us to be a good value. Thank you for mentioning our close proximity to Seattle's many attractions. We look forward to serving you again soon!
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16 helpful votes "Location could not be better"
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I was making a booking for myself and 4 friends coming to see a concert at the Paramount Theater. We all loved our stay. The Piano Guys put on a great concert, we had dinner two nights, went to Pike Place market and some shopping downtown. All within walking distance of The Roosevelt. I parked my car and never needed it during my stay. Rooms can be quite small, typical of older hotels, but were comfortable.
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Room Tip: corner rooms can be bigger than others, only 10 rooms per floor
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Helpful? Thank BararaJo Report Ask BararaJo about The Roosevelt Hotel
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I am delighted that we met your expectations during your visit and appreciate your comments about our great location. Seattle has so much to explore, we look forward to serving you on return visits!
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144 helpful votes "Ideal location but a bit long in the tooth"
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Just returned from a trip to Seattle and stayed at the Roosevelt. Wasn't expecting that I'd be there for the NFC championship when I reserved but glad I was there as the 49ers were staying right across the street at the Grand Hyatt! The location of the Roosevelt couldn't be better. You can take the train from the airport to the Westlake (last) stop. Easy walk - no car necessary! Check-in was great and I was very thankful to get checked in early and get an upgrade to a junior suite. I had a good deal on Hotwire so this was an added bonus. The junior suite was quite big and not what you'd expect from a city hotel.This is a historic hotel but I think they really need some help getting it right because it just feels old. The lobby is very outdated and couldn't be any less cool - historic can be cool if it is done right! This uncool historic theme continues to the room where it looks like your grandmother's furniture was purchased from an estate sale and thrown in. Some of the fixtures in the room were cool and modern (the lamps and USB charging plugs!) but other things were curiously outdated like some of the furniture and one of the most pathetic 80s alarm clocks I have seen in a while. It's like they had two consultants working independently to renovate the rooms and it makes the whole thing a bit of a confusing conglomeration of styles and decades. The room is clean and the bed was supremely comfortable and the pillows were some of the best I've slept on. I had a great night's sleep. There was a fridge in my room and that was appreciated. Starbucks coffee as well! The bathroom is tiny but usable. Water pressure in the shower is pretty terrible. It looks like they got new towels, which looked good, but my friend joked that I was using the bath mat towel but realized it was the regular towels. They are good looking towels that dry you like a bath mat. The bath products were good and there are dispensers in the shower for shampoo/conditioner/shower gel but also there were little bottles of it as well. The Grand Hyatt is right across the street and my friends had a room there. If you want a modern, cool hotel with style then you will want to stay there. The Roosevelt has a lot of potential but they need to figure out a better way to make historic feel hip. Maybe they should consult with the W hotel group or visit the Hotel Blackhawk in Davenport, Iowa, which is one of the best renovations of a historic hotel that I've ever seen. At least your grandma's furniture at the Roosevelt was comfortable!
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Thank everyshadeofblue Report Ask everyshadeofblue about The Roosevelt Hotel
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Thank you so much for your compliments regarding our location and comfortable pillows. We certainly appreciate all your suggestions and will utilize your comments in future planning. Thank you for providing a review!
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18 helpful votes "Amazing location, steps to EVERYTHING!"
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Beautiful hotel within steps of everything in the heart of Seattle. Super convenient to the light rail that brings you right in from the airport. Dining and entertainment are all around you, including the theater. HIGHLY RECOMMENDED!
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Helpful? Thank tgaribian24 Report Ask tgaribian24 about The Roosevelt Hotel
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We are delighted that we met your expectations during your visit and appreciate your comments about our great location. Seattle has so much to explore, we hope you return again soon!
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5 helpful votes "Always a miss."
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When I am in Seattle for business I stay at this hotel. Not by choice and I understand now why I opt to stay with family while on business. Front desk is not very welcoming. A simple request to charge my card upon arrive was like asking them to do surgery. Come on how hard is it to say hello and smile when a guest approaches the desk. If this hotel was not so close to the convention center and and wasn't the preferred vendor for my company. I would stay elsewhere.
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Helpful? Thank Amanda L Report Ask Amanda L about The Roosevelt Hotel
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