Unnamed: 0
int64
MaxAbsEStateIndex
float64
MaxEStateIndex
float64
MinAbsEStateIndex
float64
MinEStateIndex
float64
qed
float64
MolWt
float64
HeavyAtomMolWt
float64
ExactMolWt
float64
NumValenceElectrons
int64
NumRadicalElectrons
int64
MaxPartialCharge
float64
MinPartialCharge
float64
MaxAbsPartialCharge
float64
MinAbsPartialCharge
float64
FpDensityMorgan1
float64
FpDensityMorgan2
float64
FpDensityMorgan3
float64
BCUT2D_MWHI
float64
BCUT2D_MWLOW
float64
BCUT2D_CHGHI
float64
BCUT2D_CHGLO
float64
BCUT2D_LOGPHI
float64
BCUT2D_LOGPLOW
float64
BCUT2D_MRHI
float64
BCUT2D_MRLOW
float64
AvgIpc
float64
BalabanJ
float64
BertzCT
float64
Chi0
float64
Chi0n
float64
Chi0v
float64
Chi1
float64
Chi1n
float64
Chi1v
float64
Chi2n
float64
Chi2v
float64
Chi3n
float64
Chi3v
float64
Chi4n
float64
Chi4v
float64
HallKierAlpha
float64
Ipc
float64
Kappa1
float64
Kappa2
float64
Kappa3
float64
LabuteASA
float64
PEOE_VSA1
float64
PEOE_VSA10
float64
PEOE_VSA11
float64
PEOE_VSA12
float64
PEOE_VSA13
float64
PEOE_VSA14
float64
PEOE_VSA2
float64
PEOE_VSA3
float64
PEOE_VSA4
float64
PEOE_VSA5
float64
PEOE_VSA6
float64
PEOE_VSA7
float64
PEOE_VSA8
float64
PEOE_VSA9
float64
SMR_VSA1
float64
SMR_VSA10
float64
SMR_VSA2
float64
SMR_VSA3
float64
SMR_VSA4
float64
SMR_VSA5
float64
SMR_VSA6
float64
SMR_VSA7
float64
SMR_VSA8
float64
SMR_VSA9
float64
SlogP_VSA1
float64
SlogP_VSA10
float64
SlogP_VSA11
float64
SlogP_VSA12
float64
SlogP_VSA2
float64
SlogP_VSA3
float64
SlogP_VSA4
float64
SlogP_VSA5
float64
SlogP_VSA6
float64
SlogP_VSA7
float64
SlogP_VSA8
float64
SlogP_VSA9
float64
TPSA
float64
EState_VSA1
float64
EState_VSA10
float64
EState_VSA11
float64
EState_VSA2
float64
EState_VSA3
float64
EState_VSA4
float64
EState_VSA5
float64
EState_VSA6
float64
EState_VSA7
float64
EState_VSA8
float64
EState_VSA9
float64
VSA_EState1
float64
VSA_EState10
float64
VSA_EState2
float64
VSA_EState3
float64
VSA_EState4
float64
VSA_EState5
float64
VSA_EState6
float64
VSA_EState7
float64
VSA_EState8
float64
VSA_EState9
float64
FractionCSP3
float64
HeavyAtomCount
int64
NHOHCount
int64
NOCount
int64
NumAliphaticCarbocycles
int64
NumAliphaticHeterocycles
int64
NumAliphaticRings
int64
NumAromaticCarbocycles
int64
NumAromaticHeterocycles
int64
NumAromaticRings
int64
NumHAcceptors
int64
NumHDonors
int64
NumHeteroatoms
int64
NumRotatableBonds
int64
NumSaturatedCarbocycles
int64
NumSaturatedHeterocycles
int64
NumSaturatedRings
int64
RingCount
int64
MolLogP
float64
MolMR
float64
fr_Al_COO
int64
fr_Al_OH
int64
fr_Al_OH_noTert
int64
fr_ArN
int64
fr_Ar_COO
int64
fr_Ar_N
int64
fr_Ar_NH
int64
fr_Ar_OH
int64
fr_COO
int64
fr_COO2
int64
fr_C_O
int64
fr_C_O_noCOO
int64
fr_C_S
int64
fr_HOCCN
int64
fr_Imine
int64
fr_NH0
int64
fr_NH1
int64
fr_NH2
int64
fr_N_O
int64
fr_Ndealkylation1
int64
fr_Ndealkylation2
int64
fr_Nhpyrrole
int64
fr_SH
int64
fr_aldehyde
int64
fr_alkyl_carbamate
int64
fr_alkyl_halide
int64
fr_allylic_oxid
int64
fr_amide
int64
fr_amidine
int64
fr_aniline
int64
fr_aryl_methyl
int64
fr_azide
int64
fr_azo
int64
fr_barbitur
int64
fr_benzene
int64
fr_benzodiazepine
int64
fr_bicyclic
int64
fr_diazo
int64
fr_dihydropyridine
int64
fr_epoxide
int64
fr_ester
int64
fr_ether
int64
fr_furan
int64
fr_guanido
int64
fr_halogen
int64
fr_hdrzine
int64
fr_hdrzone
int64
fr_imidazole
int64
fr_imide
int64
fr_isocyan
int64
fr_isothiocyan
int64
fr_ketone
int64
fr_ketone_Topliss
int64
fr_lactam
int64
fr_lactone
int64
fr_methoxy
int64
fr_morpholine
int64
fr_nitrile
int64
fr_nitro
int64
fr_nitro_arom
int64
fr_nitro_arom_nonortho
int64
fr_nitroso
int64
fr_oxazole
int64
fr_oxime
int64
fr_para_hydroxylation
int64
fr_phenol
int64
fr_phenol_noOrthoHbond
int64
fr_phos_acid
int64
fr_phos_ester
int64
fr_piperdine
int64
fr_piperzine
int64
fr_priamide
int64
fr_prisulfonamd
int64
fr_pyridine
int64
fr_quatN
int64
fr_sulfide
int64
fr_sulfonamd
int64
fr_sulfone
int64
fr_term_acetylene
int64
fr_tetrazole
int64
fr_thiazole
int64
fr_thiocyan
int64
fr_thiophene
int64
fr_unbrch_alkane
int64
fr_urea
int64
SMILE
string
2,700
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COC1=C(C2=CC(=C3C(=C2C=C1)C=CC4=CC5=C(C=C43)OCO5)N)OC
2,701
5.626542
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C[N+]1=C2C(=C3C=CC(=C(C3=C1)OC)OC)C=CC4=CC5=C(C=C42)OCO5
2,702
10.926111
10.926111
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C1C(NC(CC1=O)C(=O)O)C(=O)O
2,703
11.339015
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406.607
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CC(CCC(=O)O)C1CCCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C
2,704
13.653997
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526.634
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206
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349,710,526.309411
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CC1(C(=O)NC(C(=O)N2CCCC2C(=O)NC(C(=O)N1)CCCCCC(=O)C3CO3)CC4=CC=CC=C4)C
2,705
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C(C(Cl)(Cl)Cl)(O)O
2,706
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C1=CC(=CC=C1CCCC(=O)O)N(CCCl)CCCl
2,707
11.698511
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0.200727
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423.205
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0
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498,027.267126
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C1=CC(=CC=C1C(C(COC(=O)CCC(=O)O)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]
2,708
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35.495691
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CN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl
2,709
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C1C2C(C(C1Cl)Cl)C3(C(C(C2(C3(Cl)Cl)Cl)Cl)Cl)Cl
2,710
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0.229193
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CN=C1CN(C(=C2C=C(C=CC2=N1)Cl)C3=CC=CC=C3)O
2,711
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C1=CC(=CC=C1NC(=NC(=NCCCCCCN=C(N)N=C(N)NC2=CC=C(C=C2)Cl)N)N)Cl
2,712
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152
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CC(=O)C1(CCC2C1(CCC3C2C=C(C4=CC(=O)CCC34C)Cl)C)OC(=O)C
2,713
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0.097099
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62
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1.972583
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COC(CNC(=[OH+])N)C[Hg]Cl
2,714
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1
COC(CNC(=O)N)C[Hg]Cl
2,715
11.996251
11.996251
0.058455
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0.781206
273.741
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0
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0
CN1C(S(=O)(=O)CCC1=O)C2=CC=C(C=C2)Cl
2,716
10.858782
10.858782
0.371041
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0.549166
221.643
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221.024356
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0
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CC(=O)OC1=C2C(=C(C=C1)Cl)C=CC=N2
2,717
6.037305
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0.441519
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319.88
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CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl
2,718
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C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)N=CN2
2,719
6.872769
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COC1=CC=C(C=C1)C(=C(C2=CC=C(C=C2)OC)Cl)C3=CC(=CC=C3)OC
2,720
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C1=CC2=C(C(=C(C=C2Cl)Cl)O)N=C1
2,721
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CC1=CC(=CC(=C1Cl)C)O
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C1=CC(=CC=C1OCC(COC(=O)N)O)Cl
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0
C(C=CC(=O)O)N
2,765
4.875
4.875
0
-0.472222
0.659756
298.03
293.998
296.939945
38
0
null
null
null
null
1
1
1
null
null
null
null
null
null
null
null
0.918296
-0
7.60964
2.707107
2.226857
6.010923
1.414214
0.239046
5.870021
0.045175
3.327989
0
0
0
0
1.188312
2.754888
16.387125
19.005779
37.349678
47.771957
12.301093
0
0
0
0
35.317037
0
0
0
0
0
0
0
0
16.480761
18.836276
0
0
0
0
0
12.301093
0
0
0
0
0
18.836276
0
16.480761
0
0
0
0
12.301093
0
67
16.480761
0
0
12.301093
0
0
0
0
0
0
18.836276
0
-0.472222
0
0
0
0
0
0
0
9.75
0
5
4
2
0
0
0
0
0
0
0
0
5
0
0
0
0
0
2.8107
22.2748
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
2
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
2
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
[NH2-].[NH2-].Cl[Pt+2]Cl
2,766
4.875
4.875
0.472222
-0.472222
0.620967
265.984
265.984
264.901399
22
0
null
null
null
null
1.333333
1.333333
1.333333
null
null
null
null
null
null
null
null
0.918296
1.632993
2.754888
2.707107
1.072157
4.856223
1.414214
0.239046
5.870021
0.045175
3.327989
0
0
0
0
1.268312
2.754888
4.268312
3.268312
3.268312
35.500456
0
0
0
0
0
35.317037
0
0
0
0
0
0
0
0
16.480761
18.836276
0
0
0
0
0
0
0
0
0
0
0
18.836276
0
16.480761
0
0
0
0
0
0
0
16.480761
0
0
0
0
0
0
0
0
0
18.836276
0
-0.472222
0
0
0
0
0
0
0
9.75
0
3
0
0
0
0
0
0
0
0
0
0
3
0
0
0
0
0
1.3765
11.706
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
2
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
Cl[Pt+2]Cl
2,767
12.949446
12.949446
0.138657
-0.281615
0.436035
465.953
436.721
465.183062
174
0
0.254909
-0.495842
0.495842
0.254909
1.28125
2.03125
2.71875
35.495692
10.002579
2.30785
-2.377277
2.288621
-2.545511
6.331526
0.005269
2.796032
1.491385
912.859666
23.087211
18.274929
19.030858
15.405417
10.483142
10.861107
7.673332
8.080532
5.526975
5.854301
3.758143
3.921806
-2.55
13,242,824.737858
24.099528
11.355007
6.245836
192.117575
30.160955
17.316245
0
0
5.90718
0
4.794537
4.390415
0
0
11.60094
43.173479
32.810434
42.135958
23.395541
23.195506
0
10.216698
0
24.98745
46.194414
52.801508
0
11.499024
20.524182
10.077801
11.499024
11.60094
63.413643
4.736863
5.817221
23.199632
36.398202
5.022633
0
0
86.05
0
9.184952
0
23.870208
40.924133
25.931156
25.308899
25.308899
0
10.216698
31.545196
29.54568
6.092332
15.14933
3.34875
6.492605
0.463472
8.920084
1.417618
2.888253
3.12632
0.434783
32
3
7
0
1
1
2
0
2
6
2
9
9
0
1
1
3
3.3581
122.0366
0
0
0
1
0
0
0
0
0
0
1
1
0
0
0
1
1
1
0
0
1
0
0
0
0
0
0
1
0
1
0
0
0
0
2
0
0
0
0
0
0
3
0
0
2
0
0
0
0
0
0
0
0
0
0
2
0
0
0
0
0
0
0
0
0
0
0
0
0
1
0
0
0
0
0
0
0
0
0
0
0
0
0
1
0
COC1CN(CCC1NC(=O)C2=CC(=C(C=C2OC)N)Cl)CCCOC3=CC=C(C=C3)F
2,768
4.875
4.875
0.472222
-0.472222
0.620967
265.984
265.984
264.902496
24
0
null
null
null
null
1.333333
1.333333
1.333333
null
null
null
null
null
null
null
null
0.918296
1.632993
2.754888
2.707107
1.072157
4.856223
1.414214
0.239046
5.870021
0.045175
3.327989
0
0
0
0
1.268312
2.754888
4.268312
3.268312
3.268312
35.500456
0
0
0
0
0
35.317037
0
0
0
0
0
0
0
0
16.480761
18.836276
0
0
0
0
0
0
0
0
0
0
0
18.836276
0
16.480761
0
0
0
0
0
0
0
16.480761
0
0
0
0
0
0
0
0
0
18.836276
0
-0.472222
0
0
0
0
0
0
0
9.75
0
3
0
0
0
0
0
0
0
0
0
0
3
0
0
0
0
0
1.3765
11.706
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
2
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
Cl[Pt]Cl
2,769
13.36732
13.36732
0.249777
-0.562471
0.838867
324.399
303.231
324.163792
124
0
0.122731
-0.36084
0.36084
0.122731
1.208333
1.958333
2.625
19.142143
9.813482
2.408959
-2.308291
2.451029
-2.283203
5.474587
-0.013956
2.939912
2.018403
764.198583
17.15649
14.050519
14.050519
11.547679
8.132551
8.132551
6.513142
6.513142
4.58819
4.58819
3.408709
3.408709
-2.22
348,132.584502
16.631264
6.721078
3.055802
141.833697
9.636773
11.418272
0
0
0
0
0
4.390415
5.261892
0
18.199101
74.437566
0
18.239555
9.127278
0
5.261892
4.89991
0
25.049576
20.6401
70.535596
0
6.069221
0
4.390415
0
0
25.54001
16.944796
17.148334
35.095449
42.464569
0
0
0
36.26
5.601051
4.390415
0
5.817221
12.170333
36.076754
12.132734
12.132734
32.294445
10.969131
9.998755
19.635225
0
2.145837
9.111023
3.175264
-0.249777
14.458155
1.777312
1.43265
4.097646
0.35
24
0
3
0
1
1
2
0
2
3
0
4
5
0
0
0
3
3.81298
90.914
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
2
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
2
0
1
0
0
0
0
1
0
0
1
0
0
0
0
0
0
0
0
0
0
0
0
1
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
2,770
12.020602
12.020602
0.066855
-5.191547
0.185283
489.335
462.119
489.114607
178
0
0.480826
-0.385174
0.480826
0.385174
1.322581
1.935484
2.516129
31.270369
10.004165
2.508914
-2.270854
2.60317
-2.472335
7.60751
-0.869963
2.870532
1.980627
935.572141
23.664926
17.097839
18.886693
14.036841
8.867988
11.858878
7.931584
10.975402
4.150914
6.766069
2.451559
4.570887
-1.22
2,332,198.415376
26.035687
9.334083
7.409231
176.925816
34.953439
30.674518
6.227901
0
0
21.335138
13.614594
13.924634
9.29461
0
0
6.066367
6.196844
34.35678
51.707994
21.463257
0
9.551078
0
17.932918
53.242086
22.747491
0
0
11.423411
5.817863
0
15.645394
93.247422
27.225085
0
6.227901
17.057748
0
0
0
212.89
52.48182
33.924512
0
12.424745
11.027787
4.5671
12.263211
21.143016
0
18.342104
10.47053
43.701683
0
34.672536
20.876914
2.271267
-0.066855
1.262345
-2.005296
-1.588028
-4.763454
0.714286
31
6
15
0
1
1
0
1
1
12
5
17
10
0
1
1
2
-1.5969
104.394
0
2
1
1
0
2
0
0
0
0
0
0
0
0
0
3
0
1
0
1
0
0
0
0
0
0
0
0
0
1
0
0
0
0
0
0
0
0
0
0
0
1
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
2
2
0
0
0
0
0
1
0
0
0
0
0
0
0
0
0
0
C[N+](C)(C)CCOP(=O)(O)OP(=O)(O)OCC1(COC(C1O)N2C=CC(=NC2=O)N)O
2,771
10.874213
10.874213
0.131713
-0.266204
0.592284
159.21
150.138
159.0354
56
0
0.217588
-0.337819
0.337819
0.217588
1.8
2.5
2.9
32.166645
10.297402
2.245156
-2.055552
2.196471
-2.331899
8.006294
-0.123693
2.153966
2.404785
169.130751
7.560478
5.716309
6.532805
4.698377
3.113529
4.162284
2.167667
3.380653
1.25977
2.413673
0.808183
1.915962
-0.51
206.780719
7.595374
3.053138
1.733594
63.554147
5.316789
5.373873
5.783245
5.90718
0
0
9.589074
0
0
11.761885
0
0
19.097412
0
9.589074
23.45231
0
5.316789
0
18.718432
5.752854
0
0
0
5.316789
0
0
11.761885
22.817151
9.589074
0
13.344559
0
0
0
0
46.17
0
9.589074
0
17.064297
6.420822
5.752854
18.685622
0
0
5.316789
0
0
1.497315
21.342824
2.299769
0
0.844444
0
0.59287
1.422778
0
0.666667
10
1
3
0
1
1
0
0
0
3
1
4
1
0
1
1
1
0.1546
39.6867
0
0
0
0
0
0
0
0
0
0
2
2
0
0
0
0
1
0
0
0
0
0
0
0
0
0
0
1
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
1
1
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
1
0
0
0
0
0
0
0
0
0
CC(=O)NC1C(=O)CCS1
2,772
12.028245
12.028245
0.096958
-1.240208
0.388289
250.25
236.138
250.084124
96
0
0.289396
-0.496919
0.496919
0.289396
1.222222
1.833333
2.388889
16.482296
9.756605
2.407397
-2.32319
2.37975
-2.339807
6.346795
-0.119044
2.292029
2.694066
510.075083
13.610366
10.351223
10.351223
8.357948
5.642251
5.642251
4.556933
4.556933
3.517135
3.517135
2.306718
2.306718
-2.04
9,009.965815
12.417792
4.011092
1.544748
104.063142
14.949918
6.103966
11.356349
5.783245
5.945225
0
9.589074
0
0
0
6.923737
19.420579
11.491011
11.835185
24.538992
11.56649
0
0
5.917906
26.875178
0
34.499724
0
0
0
0
0
0
27.883511
14.325937
5.917906
20.771212
34.499724
0
0
0
83.83
23.08482
9.589074
0
17.594977
11.146209
0
6.26208
6.923737
13.847474
0
14.949918
5.32741
0
23.987918
18.093597
0.633336
-2.663601
0
1.160975
5.293698
0
0.384615
18
2
5
1
1
2
0
0
0
5
2
5
0
0
0
0
2
1.721
62.7916
0
2
1
0
0
0
0
0
0
0
2
2
0
0
0
0
0
0
0
0
0
0
0
0
0
0
3
0
0
0
0
0
0
0
0
0
1
0
0
0
0
1
0
0
0
0
0
0
0
0
0
2
2
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
CC1C(OC=C2C1=C(C(=O)C(=C(O)O)C2=O)C)C
2,773
11.034389
11.034389
0.39092
-0.39092
0.702906
206.197
196.117
206.057909
78
0
0.335697
-0.49648
0.49648
0.335697
1.133333
1.933333
2.6
16.477548
10.181463
2.063499
-2.062658
2.292659
-1.960153
5.844498
0.395642
2.264403
2.800943
541.769486
10.836499
8.442394
8.442394
7.240713
4.402501
4.402501
2.9959
2.9959
2.129871
2.129871
1.406216
1.406216
-1.97
3,172.428611
9.579886
3.647999
1.656439
86.036381
13.890877
17.082044
0
0
0
5.625586
0
4.794537
0
0
0
6.066367
18.199101
19.605819
13.890877
10.969244
0
0
0
0
14.219595
34.685592
0
11.499024
15.099312
0
11.499024
0
14.219595
0
0
0
33.477156
0
10.969244
0
48.67
5.625586
4.794537
0
0
17.082044
5.386224
6.066367
32.418696
0
0
13.890877
15.261459
0
11.034389
0.748056
0.066209
1.21
6.415032
0
0
3.098189
0.181818
15
0
4
0
0
0
1
1
2
4
0
4
2
0
0
0
2
1.8102
55.588
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
1
0
1
0
0
0
0
2
0
0
0
0
0
0
0
0
0
0
0
0
0
2
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
COC1=CC2=C(C=CC(=O)O2)C(=C1)OC
2,774
11.625161
11.625161
0.351668
-0.351668
0.670846
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