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Phosphorylated α-synuclein in the retina is a biomarker of Parkinson's disease pathology severity. These data suggest that phosphorylated α-synuclein accumulates in the retina in parallel with that in the brainincluding in early stages preceding development of clinical signs of parkinsonism or dementia. Thereforethe re...
disease. von Hippel-Lindau disease disease increases susceptibility to several malignanciesincluding renal cell carcinomahaemangioblastomas of the central nervous system or retina and phaeochromocytomas. The tumour suppressor generesponsible for the diseaseencodes for a major regulator of the hypoxic response by target...
Cascade of neural processing orchestrates cognitive control in human frontal cortex. Rapid and flexible interpretation of conflicting sensory inputs in the context of current goals is a critical component of cognitive control that is orchestrated by frontal cortex. The relative roles of distinct subregions within front...
Evaluation of Buccal Infiltration with Articaine and Inferior Alveolar Nerve Block with Lignocaine for Pulp Therapy in Mandibular Primary Molars. Articaine infiltration has the potential to replace inferior alveolar nerve block for primary mandibular molars.Failure of inferior alveolar nerve block in achieving profound...
[Artificial corneal implants (keratoprostheses) (author's transl)]. The history of keratoprosthetics and the pioneer work of Cardona et al. is described and the technical improvements in this method over the past two decades are reviewed. In additionthe results achieved in 17 personal cases are recorded. Visual acuity ...
Effect of 5% galactose diet on galactose and dulcitol in plasma and lens of male and female pigs. Plasma galactose and dulcitol levels were measured throughout the diet period and correlated with the lens dulcitol contents at the end of the period. On the first day of the diet there was no significant difference betwee...
Evolving Treatment Patterns and Outcomes of Neovascular Age-Related Macular Degeneration Over a Decade. Management of neovascular age-related macular degeneration (nAMD) has evolved over the last decade with several treatment regimens and medications. Patients with missing data for age or gender and those aged less tha...
Effects of exercise on sleep symptoms in patients with severe obstructive sleep apnea. To investigate the extent to which exercise is associated with symptoms in patients with severe obstructive sleep apnea (OSA).We included subjects with an apnea-hypopnea index > 30 eventsh who completed validated sleep and exercise q...
All right reserved. — 3rd ed. p. cm. — (Contemporary neurology series ; 55) Includes bibliographical
Modified Intrascleral Fixation for Repositioning the Dislocated Single-PieceRigid Intraocular Lens. The modified intrascleral fixation technique shows encouraging midterm results in patients with dislocated single-piecerigid polymethyl methacrylate IOLs. Larger samples and longer follow-up are required to confirm the o...
Stacked Construct: Novel Substitute for Corneal Tissue Engineering. Corneal traumainjury often results in serious complications including permanent vision loss or loss of visual acuity which demands corneal transplantations or treatment with allogenic graft tissues. There is currently a huge shortage of donor tissue wo...
Evaluation of the 2000 Breger Vision bifocal contact lens. Evaluate the 2000 bifocal contact lens on presbyopic and aphakic patients.Thirty-eight patients37 presbyopes and one aphakewere fit in the and evaluated for 6 months.Twenty patients completed 6 months of contact lens wear. Ten discontinued due to lens related p...
Scleral canal size and optic nerve head drusen. From projected optic disk photographs we measured the size of the scleral canal in two samples of emmetropic patients: one of patients with unilateral pseudopapilledema and drusen and the other of the general normal population. Measurements on the non-drusen-containing op...
The objective was to investigate the usefulness of the "liquid biopsy" of aqueous humor to predict the clinical response after intravitreal injections of anti-VEGF agents for treating diabetic macular edema For this purposeAH samples obtained during the first anti-VEGF from 31 type two diabetic patients were analyzed. ...
Congenital cataract screening in maternity wards is effective: evaluation of the Paediatric Cataract Register of Sweden. Eye screening in maternity wards is effective. Response frequency was 96% . Data were derived from the Paediatric Cataract Register (PECARE)Sweden. All Swedish children diagnosed with congenital cata...
Aesthetic assessment in periciliary "v-incision" versus conventional external dacryocystorhinostomy in Asians. "V-incision" external has a similar functional success rate to that of the conventional approach and has superior aesthetic outcomes as reported by surgeons and patients. Howevera higher proportion of trainees...
Some problems after photorefractive keratectomy. We analyzed the data from 1821 patients (2920 eyes) who received photorefractive keratectomy to investigate the postoperative complications which cause a significant decrease in visual acuity. corneal haze of grade 2 or more developed in 9 patients (11 eyes0.38%) and cor...
Glutathione and lens epithelial function. The relationship of the concentration of glutathione in lens epithelium to the transport of cations in the lens was studied by decreasing the level of in the epithelium and monitoring subsequent effects in the lens on the distribution of cationsthe activity of Na+-K+ ATPase and...
Biomarkers in the pathogenesis of epiretinal membrane and myopic traction maculopathy: Effects of internal limiting membrane incompliance and posterior staphyloma. In the myopic traction maculopathy groupthe spherical equivalent was more myopic and the axial length was longer than in the epiretinal membrane group. Myop...
Expression pattern of Zac1 mouse genea new zinc-finger protein that regulates apoptosis and cellular cycle arrestin both adult brain and along development. Using in situ hybridizationwe analyzed the expression pattern of the Zac1 gene in mouse brain during the embryonic and postnatal development. Zac1 is a new gene tha...
Coming into focus: the role of extracellular matrix in vertebrate optic cup morphogenesis. The vertebrate eye acquires its basic form during the process of optic cup morphogenesisduring which the optic vesicle emerges from the brain neuroepithelium andthrough a series of cell and tissue movementstransforms itself into ...
An in vitro comparison of the permeability of prednisoloneprednisolone sodium phosphateand prednisolone acetate across the rabbit cornea. Controversy and ambiguity in the literature concerning the corneal penetration of prednisolone acetate over Prednisolone Sodium phosphate in rabbits has recently prompted comparative...
Visual detection of Hg2+ with high selectivity using thymine modified gold nanoparticles. Herewe describe a colorimetric sensor for detecting Hg in aqueous mediawhich is simply constructed by the self-assembly of thymine acetamidoethanethiol on gold nanoparticles (AuNPs). Based on the specific interaction of Hg with tw...
Elevated advanced glycation end products are associated with subfoveal ellipsoid zone disruption in diabetic macular edema. In DMEincreased levels of AGEs are significantly associated with disruption on SD-OCT.Advanced glycation end products (AGEs)due to increased production and a slow turnover rateserve as mediators o...
We demonstrate that cyanoacrylate is safe and less resource-demanding without a requirement of second surgery to remove a tamponading agent. It could be helpful in eyes with persistent retinal detachment in colobomatous eyes. Because we were able to achieve favorable outcomes without head positioningwe believe it may a...
Noise annoyance predicts symptoms of depressionanxiety and sleep disturbance 5 years later. Cross-sectional studies have shown that noise annoyance is strongly associated with mental distresshoweverits long-term effects on mental health is unknown. Noise annoyance was assessed at baseline and 5-year follow-up (sources:...
Surface functionalized mesoporous silica nanoparticles for intravitreal application of tacrolimus. Tacrolimus (TAC)a potent immunosuppressive macrolidehas been investigated for ocular diseases due to promising results in the treatment of anterior and posterior segments eye diseases. Mesoporous and functionalized silica...
Plasma-induced graft copolymerization of onto silicone rubber and film improving rabbit corneal epithelial cell attachment and growth. poly(2-hydroxyethyl methacrylate) (pHEMA)-grafted polymer film was prepared by plasma-induced graft copolymerization onto an elastic materialsilicone rubberand a plastic materialpoly(4-...
Retinal nerve fibre and ganglion cell inner plexiform layer analysis by optical coherence tomography in asymptomatic empty sella patients. All the patients and controls competed an automated 30-2 visual field test. The mean deviation (MD)pattern standard deviation (PSD)RNFLand + thickness values obtained with were comp...
Microkeratome complications of laser in situ keratomileusis. To evaluate the incidencetypesand outcome of microkeratome complications that occur during laser in situ keratomileusis (LASIK).Retrospectivenoncomparativecase series.Three thousand nine hundred ninety-eight eyes that underwent primary by four surgeons betwee...
Factors Affecting the Outcome of Scleral Buckling Surgery for Primary Rhegmatogenous Retinal Detachment. Scleral buckle surgery is a highly effective surgery in uncomplicated retinal detachment casesand single surgery success rates are better in cases with good preoperative visual acuitypartial detachmentand clear crys...
Differential projections from the vestibular nuclei to the flocculus and uvula-nodulus in pigeons (Columba livia). The pigeon vestibulocerebellum is divided into two regions based on the responses of Purkinje cells to optic flow stimuli: the uvula-nodulus responds best to self-translationand the flocculus responds best...
Donation after cardiac death: lessons learned. Despite the increasingly positive outcome of organ transplantation as an accepted treatment of end-stage organ diseasesan average of 15 people die each day awaiting organ transplantation. According to the United Network for Organ Sharingthere are more than 90,000 people in...
Unusual maculopathy secondary to hypergammaglobulinemia in a patient with systemic lupus erythematosus. Patients with atypical macular detachment may be afflicted with a serum immunogammopathy such as multiple myelomaWaldenström's macroglobulinemiaand benign polyclonal gammopathy. Systemic lupus erythematosus should al...
Plasmacytoma associated with canaliculitis. Plasmacytomas are plasma cell neoplasms that rarely involve ocular adnexal tissues as a primary lesion or secondary manifestation of plasma cell myeloma. Only one case of plasmacytoma involving the lacrimal drainage systemto our knowledgeis described in the literature. The cl...
Crystalline lens gradient refractive index distribution in the guinea pig. The crystalline lens undergoes morphological and functional changes with age and may also play a role in eye emmetropisation. Both the geometry and the gradient index of refraction distribution contribute to the lens optical properties. Treated ...
Cyclic nucleotide-gated channels in non-sensory organs. Cyclic nucleotide-gated channels represent a class of ion channels activated directly by the binding of either cyclic-GMP or cyclic-AMP. They carry both mono and divalent cationsbut select calcium over sodium. In the majority of the cases studiedbinding of cyclic ...
Two major tachykininssubstance and substance Kare localized to distinct subsets of amacrine cells in the anuran retina. Tachykinins are known to be major excitatory neuromodulators in neural systemsincluding the retina of many vertebrate species. Among them substance has been detected in several speciesincluding anuran...
repairrecombination protein promotes the progression of lung adenocarcinoma by activating mTORC1 pathway. Lung adenocarcinoma is the most prevalent form of lung cancer and has a poor prognosis. is a repair protein upregulated in several cancer typesbut its role in progression remains unclear. The Cancer Genome Atlas da...
Endoscopic removal of nasoglabellar dermoid cysts. Dermoid cysts are common tumors resulting from entrapped ectodermal elements at fetal suture lines. Management is conceptually straightforwardwith surgical excision of the mass in its entirety without rupture. The conspicuous location and potential scarring from direct...
Current molecular methods in epidemiological typing of Acinetobacter baumannii. The emergence of Acinetobacter baumannii during recent decades as an important nosocomial pathogen responsible of worldwideintensively documentedoutbreaks has resulted in a need for effective epidemiological typing methods. Throughout the y...
Use of 0.5% apraclonidine solution in evaluation of blepharoptosis. Of these37 eyelids had acquired ptosis and 8 had congenital ptosis. Palpebral fissure height and margin-reflex distance in the upper eyelid were measured before and after instillation of 0.5% apraclonidine2.5% phenylephrineand both drugs.After instilla...
[Selected cases of eyelid and orbit abnormalities and possibilities for correction]. The article presents abnormalities of the eyelidsthe orbita and the periorbital areas. One part of these conditions disrupts visionthe main function of the eye. The other reasons why they require correction are the aesthetic value of t...
Ten-year outcomes in newly diagnosed glaucoma patients: mortality and visual function. Approximately two thirds of patients will still be under care 10 years after presentation. In olderwhite patients with glaucoma the overall goal of preventing visual handicap is achievable for most patients 10 years after diagnosis.T...
[Ion-sensitive nanoemulsion-in situ gel system for ophthalmic delivery of flurbiprofen axetil]. Production of nanoemulsion was based on high-speed shear and homogenization processand then mixed with gellan gum to prepare images suggested no significant changes in particle morphology of the pre and post gelation. Good o...
The anti-excitotoxic effects of certain anestheticsanalgesics and sedative-hypnotics. Various agents were tested for their ability to antagonize the acute excitotoxic action of N-methyl-DL-aspartate and kainic acid on neurons in the in vitro chick embryo retina. The following compounds (in order of descending potencies...
The physiological impact of microRNA gene regulation in the retina. microRNAs (miRNAs) are smallstable molecules that post-transcriptionally regulate gene expression in plants and animals by base pairing to partially complementary sequences on target mRNAs to inhibit protein synthesis. More than 250 miRNAs are reported...
To investigate the effect of flap thickness on wavefront aberrations induced by was performed on 56 eyes of 28 patients with refraction errors that were well matched between the right and left eyes. For each patienta planned 160-microm flap was created for one randomly selected eye using the Moria microkeratome (130-mi...
Identification of the retinoschisin-binding site on the retinal NaK-ATPase. X-linked juvenile retinoschisis is a hereditary retinal dystrophycaused by mutations in the gene which encodes the secreted protein retinoschisin. In recent yearsseveral molecules have been proposed to interact with retinoschisinincluding the r...
Radiology reading-caused fatigue and measurement of eye strain with critical flicker fusion frequency. declines after reading and can be considered useful as an indicator of fatigue induced by radiology reading. questionnaire was also completed on duration of sleep the night before the experimentaverage duration of sle...
Laser treatment to large iris cyst secondary to trabeculectomy. We report a case of postoperative large iris cyst secondary to trabeculectomy treated with Nd:YAG laser iridocystotomy. The patient was subsequently free of discomfort or significant inflammation.This case suggests that large iris cysts may produce corneal...
Phosphorylated neurofilament heavy chain is a marker of neurodegeneration in Leber hereditary optic neuropathy To determine the profile of neurodegeneration in Leber hereditary optic neuropathy (LHON).We quantitated serum levels of phosphorylated neurofilament heavy chain (pNF-H) in a Brazilian pedigree of 16 affected ...
The pattern and distribution of malignant neoplasms among Yemeni patients. Gastrointestinal tract in general with breast in femaleswere the most frequent sites of malignancies in the Republic of Yemen. All specimens were diagnosed by one pathologist based on the International Classification of Disease for Oncology.Resu...
Evidence for asialo as a corneal glycolipid receptor for Pseudomonas aeruginosa adhesion. Anti-gangliotetraosylceramide (anti-asialo and antiparagloboside monoclonal antibodies (MAbs) were used in immunofluorescenceimmunoelectron-microscopicand in vitro binding inhibition assays to determine whether either of the glyco...
Trapped Pre-Macular Bubble of Octafluoropropane Gas Masquerading as Retained Submacular Perfluorocarbon Liquid. Submacular entrapment of various substances used during vitrectomy has been described in a number of case reports and case series. To our knowledgethis is the first described case of a retained fragment of fl...
Head-down posture induces alterations in early glaucoma. To probe susceptibility of retinal ganglion cells to physiological stressors associated with moderate head-down body tilt in patients with suspicion of glaucoma or early manifest glaucoma (EMG).One hundred nine subjects with best corrected visual acuity ≥ 2020 an...
Evaluating the role of retinal membrane guanylyl cyclase 1 (RetGC1) domains in binding guanylyl cyclase-activating proteins (GCAPs). Retinal membrane guanylyl cyclase 1 (RetGC1) regulated by guanylyl cyclase-activating proteins (GCAPs) controls photoreceptor recovery and when mutated causes blinding disorders. We evalu...
Femtosecond laser corneal refractive surgery for the correction of high myopic anisometropic amblyopia in juveniles. or can be promising alternative methods to correct high myopic anisometropic amblyopia in juvenile patients who have failed with traditional approaches.To evaluate the effects of femtosecond laser-assist...
Rapid and delayed death of cultured trabecular meshwork cells after selective laser trabeculoplasty. Selective laser trabeculoplasty is becoming increasingly employed to reduce elevated intraocular pressure in glaucoma patients. is known to target the ocular trabecular meshwork (TM)but the exact response mechanisms to ...
Nonresonant Raman imaging of protein distribution in single human cells. It is shown that high quality Raman imaging of the protein distribution can be obtained using confocal nonresonant Raman imaging (lambda(exc) = 647.1 nm). The results are shown for two different human cell types. Perpheral blood lymphocytes are us...
severe case of Moebius syndrome with calcification on the fourth ventricular floor. We report the case of a Japanese girl with a severe type of Moebius syndrome. Her morphological features were a mask-like facelimitation of horizontal eye movementssevere bulbar palsymultiple and bilateral arthrogryposis including the e...
Rab10Crag and Ehbp1 regulate the basolateral transport of Na+K+ATPase in Drosophila photoreceptors. Cells in situ are often polarized and have multiple plasma membrane domains. To establish and maintain these domainspolarized transport is essentialand its impairment results in genetic disorders. Neverthelessthe underly...
The irre cell recognition module protein Kirre is required to form the reciprocal synaptic network of neurons in the Drosophila lamina. Each neuropil moduleor cartridgein the fly's lamina has a fixed complement of cells. Of five types of monopolar cell interneuronsonly has collaterals that invade neighboring cartridges...
The multifocal visual evoked potential. With the multifocal techniquevisual evoked potentials (VEPs) can be recorded simultaneously from many regions of the visual field. For the multifocal (mfVEP)the patient views a display that typically contains 60 sectorseach with a checkerboard pattern. The display covers about th...
case of recurrent transient monocular visual loss after receiving sildenafil. 53-year-old man was attended to the Clinic Ophthalmic CenterMansoura UniversityEgyptwith recurrent transient monocular visual loss after receiving sildenafil citrate (Viagra) for erectile dysfunction. Examination for possible risk factors rev...
Exploring spike transfer through the thalamus using hybrid artificial-biological neuronal networks. We use dynamic clamp to construct "hybrid" thalamic circuits by connecting a biological neuron in situ to silicon- or software-generated "neurons" through artificial synapses. The purpose is to explore cellular sensory g...
Unscheduled re-entry into the cell cycle induced by precedes cell death in nascent retinal neurones. During their early postmitotic lifea proportion of the nascent retinal ganglion cells (RGCs) are induced to die as a result of the interaction of nerve growth factor with the neurotrophin receptor p75. To analyse the me...
Location of the inferior oblique muscle origin with reference to the lacrimal caruncle and its significance in oculofacial surgery. To identify the location of the inferior oblique muscle origin with reference to the lacrimal caruncle in order to facilitate safer oculofacial surgery by preventing morbidity associated w...
Functional characterization of folate transport proteins in Staten's Seruminstitut rabbit corneal epithelial cell line. Folic acid uptake was studied with respect to timepHtemperaturesodiumand chloride ion dependency. Inhibition studies were conducted with structural analogsvitaminsand metabolic inhibitors. Folic acid ...
New Therapies of Neovascular beyond Anti-VEGF Injections. Neovascular age-related macular degeneration is a leading cause of vision loss among the aging population. The current standard of care to treat neovascular age-related macular degeneration is inhibiting vascular endothelial growth factor through intravitreal in...
Agreement of corneal measurements between dual rotating Scheimpflug-Placido system and Placido-based topography device in normal and keratoconus eyes. Placido-based topography underestimated all topographic values except and in healthy eyes and J0maximum corneal power pointand in keratoconus eyeswith statistically sign...
Apoptotic effects of topical antiglaucoma medications on conjunctival epithelium in glaucoma patients. Apoptotic effects of topical antiglaucoma drugs on the conjunctival epithelial cells were found. Thirty patients were included in the first group who had received antiglaucomatous therapy before trabeculectomy. In the...
Tomographic Findings After Implantation of Ferrara Intrastromal Corneal Ring Segments in Keratoconus. Computed tomography scans of the two corneal surfaces were obtained preoperatively and postoperatively with a rotating Scheimpflug imaging system. Both corneal surfaces showed statistically significant decreases in ave...
Corneal sensation after corneal refractive surgery with small incision lenticule extraction. One eye of each patient was treated by SMILEand the fellow eye was treated by Mean outcome measures Cochet-Bonnet esthesiometrySchirmer test with anesthesiatear breakup timeand tear film osmolarity were evaluated preoperatively...
Ocular motility in thalidomide embryopathy. Twenty-one individualsaged 28 to 29 yearswith documented thalidomide embryopathy were examined in Sweden. The most noteworthy ophthalmologic finding was the high prevalence of incomitant horizontal strabismusprimarily of the Duane syndrome type. Less frequently seen were case...
In vivo single-cell excitability probing of neuronal ensembles in the intact and awake developing Xenopus brain. Sensory experience can elicit long-lasting plasticity of both single neurons and ensemble neural circuit response properties during embryonic development. To investigate their relationshipone must image func...
The burden of non-infectious intraocular inflammatory eye diseases: a systematic literature review. Non-infectious inflammatory eye diseases (IEDs)although rareare complex and varied and may result in detrimental effects. systematic literature review was conducted on the clinical outcome and economic burden of IED.The ...
Role of Cataract Surgery in the Management of Glaucoma. leading cause of blindnessglaucoma is estimated to affect 60.5 million people worldwidewith a projected increase to 79.6 million by 2020. Cataract surgery is the most commonly performed ophthalmic surgerywith the anticipated number of people requiring cataract sur...
Static roll and pitch in the monkey: shift and rotation of Listing's plane. In three rhesus monkeys three-dimensional eye positions were measured with the dual search coil technique. Recordings of spontaneous eye movements were made in the light and in the darkwith the monkeys in different static roll or pitch position...
Telephone talk: effects of two access methods on phone call success. The slower and unnatural timing of speech inherent to speech-generating devices (SGDs) can be a barrier to successful aided telephone calls. The timing of message delivery when using an may vary depending on the type of access method used. We measured...
Three-dimensional digital visualization of phacoemulsification and intraocular lens implantation. The heads-up vision system is suitable and safe for cataract phacoemulsification and implantation. Ocular and surgical parameters such as surgery timepre and postoperative best-corrected visual acuity (BCVA)and corneal end...
Substance P-immunoreactive neurons in the human retina. Substance is a neuropeptide that acts as a neurotransmitter or a neuromodulator in the retina. We have used an antiserum to to immunostain neurons in postmortem human retinae. Immunostained retinae were processed with the avidin-biotin complex to visualize the cel...
[Clinical features and therapy of uveitis in childhood]. Introduction: Uveitis is characterized by inflammation of the middle layer of the eye. Its overall incidence is low. Autoimmune diseases and infections are the most common underlying diseases. Out of the autoimmune diseasesjuvenile idiopathic arthritis is associa...
Fukutin and alpha-dystroglycanopathies. Fukuyama-type congenital muscular dystrophy (FCMD)Walker-Warburg syndrome (WWS)and muscle-eye-brain disease are clinically similar autosomal recessive disorders characterized by congenital muscular dystrophylissencephalyand eye anomalies. We identified the gene for and MEBwhich e...
Next-Generation Sequencing Identifies Novel Variants in Patients with Late-Onset Dominant Optic Atrophy. Dominant Optic Atrophy is one of the most common inherited mitochondrial diseasesleading to blindness. It is caused by the chronic degeneration of the retinal ganglion cells (RGCs) and their axons forming the optic ...
Change of water-soluble-proteinurea-soluble-protein and membrane intrinsic protein in human senile cataract. The water-insoluble proteinwhether in quantity or in qualityplays an important role in cataract formation.To analyze the change of water-soluble-protein (WSP)urea-soluble-protein and membrane intrinsic protein i...
Transport of fluorescein in the rabbit eye after treatment with sodium iodate. The outward active transport and the inward permeability of the blood-retinal barrier were studied in the rabbit eye after i.v. administration of sodium iodate. The active transport was evaluated from the half-time of disappearance of the vi...
Molecular profiling of resident and infiltrating mononuclear phagocytes during rapid adult retinal degeneration using single-cell sequencing. Neuroinflammation commonly accompanies neurodegenerationbut the specific roles of resident and infiltrating immune cells during degeneration remains controversial. Much of the di...
Fast Phenomics in Vineyards: Development of GRoverthe Grapevine Roverand LiDAR for Assessing Grapevine Traits in the Field. light detection and ranging (LiDAR) radar mounted on GRover was capable of producing precise (±3 mm) point clouds of vine rows. Vineyard scans of the grapevine variety Shiraz grown under different...
[Retinal nerve fiber layer thickness in glaucomatous eyes. To investigate the retinal nerve fiber layer thickness in glaucomatous eyes using Optical Coherence Tomography To compare the thickness with visual field damage (Humphrey field analyzer).The mean thickness in glaucomatous eyes (n = 80) was compared with age-mat...
Chlamydiosis in birds in Great Britain. 2. Isolations of Chlamydia psittaci from birds sampled between 1976 and 1984. total of 1531 diagnostic submissions from birds were examined by culture for the presence of Chlamydia psittaci between June 1976 and December 1984 by growth in 929 clone mouse fibroblast cellspretreate...
Anaerobic flora of the conjunctival sac in patients with and with anophthalmia compared with normal eyes. Relatively few investigations of anaerobic bacteria as ocular flora have been conductedand their results have been contradictory. The conjunctival sacs of 22 normal subjects and of 14 patients with acquired immunod...
Zinc Monotherapy as an Alternative Treatment Option for Decompensated Liver Disease due to Wilson Disease? Wilson disease is a rare metabolic disorder involving copper metabolismand patients may present with a variable degree of hepaticneurologicand psychiatric manifestations. In the case of hepatic presentationtreatme...
standard enucleation procedure was performedand each patient was randomized to receive either Medpor or Medpor-Plus orbital implant with anterior scleral cap technique. Gadolinium-enhanced3-Tesla was performed at 1.5 months3 monthsand 4.5 months following surgery. Implant vascularization was calculated in axialcoronala...
Correction to: zebrafish model of foxe3 deficiency demonstrates lens and eye defects with dysregulation of key genes involved in cataract formation in humans. The authors noticed that Fig. and aspect ratios appeared sub-optimal in the online published version. This has now been changed.
programme to improve quality of care for patients with chronic diseasesKazakhstan. This intensivesupportivemultifaceted programme was associated with significant improvements in quality of care for patients with chronic disease. Further investment in coaching capacity is needed to extend the programme nationally.To eva...
The influence of corneal collagen cross-linking on anterior chamber in keratoconus. The preoperative (T0)postoperative 6th month (T1)and postoperative 1st year anterior chamber volume (ACV)anterior chamber angle (ACA)and anterior chamber depth scheimpflug imaging values were obtained for each eye.The mean value was 182...
Frequent Mutation in the Gene Causing Hyperferritinemia Cataract Syndrome in Turkish Population Is c.-160A>G. In the Turkish populationthe prevalence of is about 1100,000 and the commonly observed mutation is c.-160A>G mutation.Hyperferritinemia cataract syndrome is an autosomal dominantly inherited disease characteriz...
Recombinant human serum albumin for corneal preservation. The tissues were assessed at day 0; after 6 days of preservation at room temperature in Cornea Trans® and Cornea Prep ; after 28 days at in Cornea Syn® [with rHSA] and Cornea Max® [with foetal calf serum and; 4-day post deswelling in Cornea Trans® and Cornea Jet...
In this techniquethe dislocated is not taken in the anterior segment before the scleral fixation. The haptics are threaded into the needle directly in the vitreous cavity during the vitrectomy. This is a short cut Yamane technique for posteriorly dislocated three-piece IOLs. This technique may shorten the surgical time...
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EYE-lit Dataset

Dataset Overview

The EYE-lit dataset is designed specifically for training language models in the field of ophthalmology. It contains ophthalmic data collected from various sources, including PubMed abstracts and ophthalmology-related articles. By focusing exclusively on ophthalmic terminology and concepts, this dataset enables models to adapt effectively to the unique language and nuances of the domain.

Sources:

  • PubMed Abstracts: We collected approximately 744k ophthalmic abstracts using specific ophthalmic keywords (e.g., ophthalmology, retina, cataract, glaucoma, etc.). This data was retrieved from the PubMed database using the BioPython Entrez system.
  • Textbooks and Wikipedia: We expanded the dataset using 570 textbooks and full articles from ophthalmology-related articles on Wikipedia.

Dataset Composition:

Source Percentage License Number of Tokens
Online Articles 2% Open access ~5 million
PubMed Abstracts 98% Open access ~248 million

Features:

  • text: A string field containing the text of the abstract or article.

Dataset Splits:

  • train: 755,937 examples (973MB)
  • dev: 10,000 examples (12MB)

Total Dataset Size:

  • Download size: ~548MB
  • Dataset size: ~986MB

Data Format:

The dataset is provided in the following format:

  • Split: train, dev
  • File paths:
    • data/train-*
    • data/dev-*

License

This dataset is distributed under the CC BY 4.0 License. You are free to use, modify, and distribute this dataset, provided that you give appropriate credit.

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