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license: cc-by-4.0

A Dataset of Small Protein Conformational Ensembles from All-Atom Molecular Dynamics Simulations

Authors

Zilin Ren, Ying Hu, Xin Yang


Dataset Overview

This dataset, hereafter referred to as DynoDB, consists of 8,385 molecular dynamics (MD) trajectories of small proteins (5–100 amino acids). Each entry contains 1,000 ensemble frames extracted from 100 ns production runs, providing a systematic characterization of small protein conformational landscapes at the atomic scale.

License

This dataset is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). By using this dataset, you agree to cite the original work as specified below.

Citing The Dataset

If you use this dataset in your research, please cite the following paper: [... (Scientific Data, 2026)]
DOI: https://doi.org/10.57967/HF/7057

Dataset Structure

The data is organized as follows:

  • static_structures/: Initial PDB conformations.
  • processed_structures/: Preprocessed and repaired models.
  • trajectory_frames/: Extracted frames (1,000 per system).
  • metadata/: Multi-sheet Excel/CSV files providing comprehensive structural, dynamic, and functional annotations.

Dataset Size

Dataset Metric Value
Number of trajectories 8,385
Length per trajectory 100 ns
Cumulative simulation time 838.5 µs (~0.84 s)
Total number of atoms 3,990,516
Average system size (atoms) ~476
Total number of residues 491,395
Average system size (residues) ~59
Storage size ~611 GB