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0 | PV generation and load profile data of net zero energy homes in South Australia | Fig. 1 shows the general configuration of a Net Zero Energy home.The data is supplied in two separate Excel files: one containing raw half-hourly load data for a region in South Australia, and the other containing PV generation and load data scaled down for a single home.Examining the second file will reveal that it co... | This paper presents the hourly Photovoltaic (PV) generation and residential load profiles of a typical South Australian Net Zero Energy (NZE) home. These data are used in the research article entitled “Energy Cost Minimization for Net Zero Energy Homes through Optimal Sizing of Battery Storage System” Sharma et al., 20... |
1 | The synthesis of recombinant membrane proteins in yeast for structural studies | The first crystal structures of mammalian membrane proteins derived from recombinant sources were solved in 2005 using protein that had been produced in yeast cells: the rabbit Ca2+-ATPase, SERCA1a, was overexpressed in Saccharomyces cerevisiae and the rat voltage-dependent potassium ion channel, Kv1.2 was produced in ... | Historically, recombinant membrane protein production has been a major challenge meaning that many fewer membrane protein structures have been published than those of soluble proteins. However, there has been a recent, almost exponential increase in the number of membrane protein structures being deposited in the Prote... |
2 | ACP-DL: A Deep Learning Long Short-Term Memory Model to Predict Anticancer Peptides Using High-Efficiency Feature Representation | Cancer is one of the most devastating killers of human beings, accounting for millions of deaths around the world each year.1,2,Conventional physical and chemical methods, including targeted therapy, chemotherapy, and radiation therapy, remain the principle modes to treat cancer, which focus on killing the diseased cel... | Cancer is a well-known killer of human beings, which has led to countless deaths and misery. Anticancer peptides open a promising perspective for cancer treatment, and they have various attractive advantages. Conventional wet experiments are expensive and inefficient for finding and identifying novel anticancer peptide... |
3 | Influence of alkalinity and temperature on photosynthetic biogas upgrading efficiency in high rate algal ponds | Biogas from the anaerobic digestion of organic matter constitutes a promising renewable energy vector for the production of heat and power in households and industry .Raw biogas is mainly composed of CH4, CO2 and other components at lower concentrations such as H2S, oxygen, nitrogen, siloxanes, ammonia and halogenated ... | Algal-bacterial photobioreactors have emerged as a cost-effective platform for biogas upgrading. The influence on biomethane quality of the inorganic carbon concentration (1500, 500 and 100 mg L−1) and temperature (12 and 35 °C) of the cultivation broth was evaluated in a 180 L high rate algal pond (HRAP) interconnecte... |
4 | The genome of the protozoan parasite Cystoisospora suis and a reverse vaccinology approach to identify vaccine candidates | Cystoisospora suis is a protozoan parasite of the phylum Apicomplexa.This phylum contains almost exclusively obligate endoparasites of animals, including species of great medical and veterinary relevance such as Plasmodium falciparum and Toxoplasma gondii.According to recent reevaluations of the coccidian phylogeny, th... | Vaccine development targeting protozoan parasites remains challenging, partly due to the complex interactions between these eukaryotes and the host immune system. Reverse vaccinology is a promising approach for direct screening of genome sequence assemblies for new vaccine candidate proteins. Here, we applied this para... |
5 | Drivers and emerging innovations in knowledge-based destinations: Towards a research agenda | Understanding the drivers and the typologies of innovation in destinations represents one of the main challenges for academics, policy makers and managers who are called on to define the evolutionary process of tourism in the complexity of human-technology interaction.The phenomenon of innovation has been receiving inc... | Research on innovation in tourism is fragmented and confined to traditional paradigms. This critical review paper, which cross-fertilises and discusses the relevant literature in tourism and other theoretical domains, proposes an integrative theoretical framework of innovation in destinations. The paper identifies four... |
6 | Quantitative multiplex one-step RT-PCR assay for identification and quantitation of Sabin strains of poliovirus in clinical and environmental specimens | Starting in 1988, the World Health Organization has led a worldwide campaign to eradicate poliomyelitis.As a result, the number of poliomyelitis cases has dropped dramatically.The disease has been eliminated from most countries except few endemic regions including Afghanistan, Pakistan, in addition to few others that s... | An improved quantitative multiplex one-step RT-PCR (qmosRT-PCR) for simultaneous identification and quantitation of all three serotypes of poliovirus is described. It is based on using serotype-specific primers and fluorescent TaqMan oligonucleotide probes. The assay can be used for high-throughput screening of samples... |
7 | Acute Acalculous Cholecystitis due to primary acute Epstein-Barr virus infection treated with laparoscopic cholecystectomy; a case report | Epstein-Barr Virus is a human herpes virus 4, transmitted through intimate contact between susceptible persons and asymptomatic EBV shedders.It usually presents with fever, pharyngitis and lymphadenopathy .Majority of individuals with primary EBV infection recover uneventfully .Acute Acalculous Cholecystitis is usually... | Introduction: Epstein Barr virus (EBV) is a human herpes virus 4, transmitted through intimate contact between susceptible persons and asymptomatic EBV shedders. It usually presents with fever, pharyngitis and lymphadenopathy. Majority of individuals with primary EBV infection recover uneventfully. Acute Acalculous Cho... |
8 | Enhancing board motivation for competitive performance of Thailand's co-operatives | The main stream of board research focuses on studying the relationship between board characteristics for instance board size, board diversity, chairman-CEO duality, and the performance of the firm.However, research results are inconclusive as the relationship is not clear and the mechanism that explains the relationshi... | This study aims to answer the main questions “does the motivation of co-operative boards of directors affect co-operative performance in Thailand, and to what extent?”, and “Which factors affect the motivation of a co-operative's board of directors?” The methods used for the study is the Structural Equation Modeling (S... |
9 | Growth faltering in rural Gambian children after four decades of interventions: a retrospective cohort study | The combination of fetal growth restriction, underweight, stunting, and wasting in later childhood, suboptimal breastfeeding, and micronutrient deficiencies have been estimated to cause more than 3 million child deaths annually, equivalent to 45% of the global total.1,Among these factors, the association between undern... | Background Growth faltering remains common in children in sub-Saharan Africa and is associated with substantial morbidity and mortality. Due to a very slow decline in the prevalence of stunting, the total number of children with stunting continues to rise in sub-Saharan Africa. Identification of effective interventions... |
10 | Valuation of vegetable crops produced in the UVI Commercial Aquaponic System | Aquaponics is a food production technology that combines aquaculture and hydroponics in an integrated system.The combination is symbiotic, with each component adding advantages to the other.Fish, which are daily fed a protein-rich diet, generate waste that flows into the hydroponic system.The hydroponic system has an e... | The UVI Commercial Aquaponic System is designed to produce fish and vegetables in a recirculating aquaculture system. The integration of these systems intensifies production in a small land area, conserves water, reduces waste discharged into the environment, and recovers nutrients from fish production into valuable ve... |
11 | Reprint of Transport poverty and fuel poverty in the UK: From analogy to comparison | Domestic and transport energy consumption have traditionally belonged to distinct academic and policy silos.Recent developments, however, suggest the need for convergence.The UK is committed to reducing greenhouse gas emissions by 80% by 2050, and reductions have to be achieved across all sectors.This includes both tra... | The notion of ‘fuel poverty’ referring to affordable warmth, underpins established research and policy agendas in the UK and has been extremely influential worldwide. In this context, British researchers, official policymaking bodies and NGOs have put forward the notion of ‘transport poverty’ building on an implicit an... |
12 | Envisioning surprises: How social sciences could help models represent ‘deep uncertainty’ in future energy and water demand | Urban and regional infrastructures in the energy and water sectors tend to have a long lifespan.For this reason, strategic infrastructure-related planning has long-term consequences, shaping the systems of provision and demand patterns for decades ahead.Strategic planning is often enacted in conditions of uncertainty r... | Medium- and long-term planning, defined here as 10 years or longer, in the energy and water sectors is fraught with uncertainty, exacerbated by an accelerating ‘paradigm shift’. The new paradigm is characterised by a changing climate and rapid adoption of new technologies, accompanied by changes in end-use practices. T... |
13 | Anti-tyrosinase, total phenolic content and antioxidant activity of selected Sudanese medicinal plants | Tyrosinase is known to be a key enzyme in melanin biosynthesis and is widely distributed in plants and mammalian cells.Tyrosinase enzyme catalyzes two different reactions: the hydroxylation of monophenols to o-diphenols and the oxidation of o-diphenols to o-quinones.o-Quinone is transformed into melanin in a series of ... | The flora of Sudan is relatively rich in medicinal plants and represents an important component of traditional medicine. Fifty methanolic extracts of selected Sudanese medicinal plants were evaluated for their in vitro tyrosinase inhibitory effect, antioxidant activity and total phenolic content (TPC). The standard met... |
14 | Cofactor specificity engineering of streptococcus mutans NADH oxidase 2 for nad(p)+ regeneration in biocatalytic oxidations | Enzyme catalyzed oxidation reactions have gained increasing interest in biocatalysis recently, reflected also by a number of excellent reviews on this topic published in the last years .Oxidoreductases constitute an important group of biocatalysts as they facilitate not only the widely used stereoselective reduction of... | Soluble water-forming NAD(P)H oxidases constitute a promising NAD(P) + regeneration method as they only need oxygen as cosubstrate and produce water as sole byproduct. Moreover, the thermodynamic equilibrium of O2 reduction is a valuable driving force for mostly energetically unfavorable biocatalytic oxidations. Here, ... |
15 | A Closer Look at the Design of Cutterheads for Hard Rock Tunnel-Boring Machines | A tunnel-boring machine is a “tunnel-production factory”; as such, all parts of the production line should be functional in order to make the final product, which is the next meter of excavated tunnel.TBMs have existed since the mid-19th century, both in concept and in reality, and have been an integral part of the tun... | The success of a tunnel-boring machine (TBM) in a given project depends on the functionality of all components of the system, from the cutters to the backup system, and on the entire rolling stock. However, no part of the machine plays a more crucial role in the efficient operation of the machine than its cutterhead. T... |
16 | Draft genome of the brown-rot fungus Fomitopsis pinicola GR9-4 | We present the draft genome assembly and gene prediction of the fungus Fomitopsis pinicola, an important and ubiquitous brown-rot fungus of boreal forests causing a cubical brown-rot in both softwood and hardwood .The broad host range and phenotypic differences with respect to color and form, already observed by Fries ... | Basidiomycete brown-rot fungi have a huge importance for wood decomposition and thus the global carbon cycle. Here, we present the genome sequence of Fomitopsis pinicola GR9-4 which represent different F. pinicola clade than the previously sequenced North American isolate FP-58527 SS1. The genome was sequenced by using... |
17 | Antibody H3 Structure Prediction | Antibodies are proteins that bind to foreign objects that find their way into an organism, preventing them from causing harm and marking them for removal.A huge number of different antibodies can be produced – estimates vary, but it is thought that humans have the potential to of produce up to 1013 different antibodies... | Antibodies are proteins of the immune system that are able to bind to a huge variety of different substances, making them attractive candidates for therapeutic applications. Antibody structures have the potential to be useful during drug development, allowing the implementation of rational design procedures. The most c... |
18 | Business car owners are less physically active than other adults: A cross-sectional study | There is broad consensus that physical activity has a positive influence on health.Not only vigorous-intensity activities but also moderate-intensity activities are regarded to be effective, assuming that duration and frequency are sufficient.In addition, recent research showed that sedentary behavior -- i.e. any wakin... | Active transport contributes to increased daily physical activity (PA). Car ownership is associated with less frequent active transport and less PA. For business car ownership this relation is unknown. Therefore, we explored whether business car owners and their adult household members comply less with the Dutch modera... |
19 | Construction of a versatile SNP array for pyramiding useful genes of rice | By 2050, the world population is expected to surpass 9 billion.To address the monumental challenge of feeding 9 billion, a 70% increase in global agricultural production has to be reached , http://faostat.fao.org/default.aspx].Rice is one of the most important food crops, providing up to 76% of the caloric intake in So... | DNA marker-assisted selection (MAS) has become an indispensable component of breeding. Single nucleotide polymorphisms (SNP) are the most frequent polymorphism in the rice genome. However, SNP markers are not readily employed in MAS because of limitations in genotyping platforms. Here the authors report a Golden Gate S... |
20 | A new gamma spectroscopy methodology based on probabilistic uncertainty estimation and conservative approach | The gamma spectroscopy technique is commonly used to assess the activity of gamma emitters for the disposal of radioactive waste which needs to be conservatively evaluated, i.e. reasonably overestimating the radionuclide activity results.A framework has been previously developed to quantify and reduce uncertainties of ... | The gamma spectroscopy technique is commonly used in many applications to evaluate the activity of gamma emitters in a given sample. This assessment of activity is of particular interest for the disposal of radioactive waste or for clearance purposes. However, for these specific applications, one needs to show that the... |
21 | Estimation of own and cross price elasticities of alcohol demand in the UK-A pseudo-panel approach using the Living Costs and Food Survey 2001-2009 | The consumption of alcohol and the related health and social harms are an issue of extensive policy debate in the UK and many other countries.Price-based policy interventions, such as minimum unit pricing and increases in taxation, have been actively considered by the UK and Scottish governments who aim to reduce harmf... | The estimation of price elasticities of alcohol demand is valuable for the appraisal of price-based policy interventions such as minimum unit pricing and taxation. This study applies a pseudo-panel approach to the cross-sectional Living Cost and Food Survey 2001/2-2009 to estimate the own- and cross-price elasticities ... |
22 | Tectonostratigraphy and the petroleum systems in the Northern sector of the North Falkland Basin, South Atlantic | The Falkland Islands offshore designated area for exploration covers approximately ∼460,000 km2 and has received relatively little attention in terms of hydrocarbon exploration.It is composed of four main sedimentary basins of Mesozoic to Cenozoic-age; namely the North Falkland, Falkland Plateau, South Falkland and Mal... | The North Falkland Basin represents one of the frontier areas for hydrocarbon exploration in the South Atlantic. This study presents the results of new subsurface mapping using 2D seismic data in the north of the Falkland Islands offshore area, which has delineated a series of discrete grabens northwards of the main No... |
23 | Failing entrepreneurial governance: From economic crisis to fiscal crisis in the city of Dongguan, China | The global financial crisis in 2008 triggered a series of chain reactions across the world.The impact of globalization on the local economy may be seen in the city of Dongguan, the heartland of export-oriented economies in the Pearl River Delta.Under the export-driven economy, the Pearl River Delta experienced export-d... | This paper analyzes the recent fiscal crisis among villages in the city of Dongguan. The city has been an exemplar of export-oriented growth in China. Rapid economic development has been attributed to local state entrepreneurial governance based on a close relationship between the local state and enterprises. However, ... |
24 | DNA demethylation during Chrysanthemum floral transition following short-day treatment | The authors declare that there are no conflict of interest.DNA methylation is a common epigenetic phenomenon involving the transfer of a methyl group from S-adenosylmethionine to a specific location of the adenine purine ring or cytosine pyrimidine ring of DNA, which is catalyzed by methyltransferase .One of the most i... | Background: Analytical techniques such as methylation-sensitive amplification polymorphism and high-performance liquid chromatography were used to detect variation in DNA methylation of mature Chrysanthemum leaves during the floral transition induced by short-day (SD) treatment. Results: For both early- and late-flower... |
25 | Development and Validation of a Novel Recurrence Risk Stratification for Initial Non-muscle Invasive Bladder Cancer in Asia | Bladder cancer is the fourth most common malignancy in the West.In Asia, the incidence of bladder cancer is three to four times less than Western countries."However, population-based cancer registries covering 21% of the world's population only included 8% of patients in these registries are from Asia.At initial diagno... | Background Some risk classifications to determine prognosis of patients with non-muscle invasive bladder cancer (NMIBC) have disadvantages in the clinical setting. We investigated whether the EORTC (European Organization for Research and Treatment of Cancer) risk stratification is useful to predict recurrence and progr... |
26 | Future prediction with automatically extracted morphosemantic patterns | “Prediction is very difficult, especially about the future.,“The Press is a most valuable institution, if you only know how to use it.,– Arthur Conan Doyle.When an average person is in a need to make a prediction about how an event will potentially unfold, a good choice would be to first ask for advice of an expert, wh... | In the following paper, we investigated the usefulness of future reference sentence patterns in the prediction of the unfolding of future events. To obtain such patterns we first collected sentences that have any reference to the future from newspapers and Web news. Based on this collection, we developed a novel method... |
27 | Business model innovation: How the international retailers rebuild their core business logic in a new host country | Internationalization of the firm can be understood as an innovation decision process.Moreover, the extant research suggests that organizational learning, innovation and internationalization are linked together in a complex way.Reflecting on the significant advancement in international business literature since the Upps... | Although research into the business model has received increasing attention, few studies have so far been conducted on business model innovation in an international context. The purpose of the study is to identify different patterns of business model innovation which enables international retailers to rebuild their cor... |
28 | Modelling aeolian sand transport using a dynamic mass balancing approach | A central aspect of understanding desert landscape dynamics relies on the quantification of surface deposition and erosion.Numerous formulae have been developed to predict sediment flux and these generally rely on temporally- and spatially-averaged measures of erosivity such as wind velocity and shear velocity.No singl... | Knowledge of the changing rate of sediment flux in space and time is essential for quantifying surface erosion and deposition in desert landscapes. Whilst many aeolian studies have relied on time-averaged parameters such as wind velocity (U) and wind shear velocity (u⁎) to determine sediment flux, there is increasing f... |
29 | The motor repertoire in 3- to 5-month old infants with Down syndrome | Even though Down syndrome is the most common chromosomal cause of intellectual disability, with 20–22 individuals per 10,000 births affected, studies on early development are scarce.Infants with Down syndrome are known to be socially competent but show a delay in the acquisition of motor milestones and deficits in earl... | Background Even though Down syndrome is the most common chromosomal cause of intellectual disability, studies on early development are scarce. Aim To describe movements and postures in 3- to 5-month-old infants with Down syndrome and assess the relation between pre- and perinatal risk factors and the eventual motor per... |
30 | Influence of cultivars and processing methods on the cyanide contents of cassava (Manihot esculenta Crantz) and its traditional food products | Cassava is a staple food consumed worldwide with an estimated 800 million consumers .It is cultivated mainly for its roots and leaves and have acceptable production yield in poor soils with low nutrient availability .In Cameroon, cassava root is a very significant food product with annual production estimated at 4.5 mi... | Cyanide is a toxic substance found in several plants roots amongst which cassava. The objectives of this study were to quantify cyanide contents in the roots of the main cassava varieties cultivated in Cameroon and evaluate the effect of some traditional cassava processing methods on their initial contents. Ten local a... |
31 | Light conditions affect rhythmic expression of aquaporin 5 and anoctamin 1 in rat submandibular glands | Circadian rhythms, which measure time on a scale of 24 h, regulate various physiological functions such as sleep cycle, blood pressure, hormone secretion, metabolism and salivary secretion in mammals .The rhythm is orchestrated by a master clock and several peripheral biological clocks.The master clock, which is locate... | Circadian rhythms regulate various physiological functions and are, therefore, essential for health. Light helps regulate the master and peripheral clocks. The secretion rates of saliva and electrolytes follow a circadian rhythm as well. However, the relationship between the molecular mechanism of saliva water secretio... |
32 | Screening tool to evaluate the vulnerability of down-gradient receptors to groundwater contaminants from uncapped landfills | In 2010 there were 1908 operational municipal landfill facilities in the U.S. which received 135 million tons of waste and more than 10,000 closed landfills in the U.S.Problems associated with open and closed landfills include gas emissions, contaminated leachates, physical hazards, aesthetic issues, and others.These i... | A screening tool for quantifying levels of concern for contaminants detected in monitoring wells on or near landfills to down-gradient receptors (streams, wetlands and residential lots) was developed and evaluated. The tool uses Quick Domenico Multi-scenario (QDM), a spreadsheet implementation of Domenico-based solute ... |
33 | The effect of ultrasound treatment on the structural, physical and emulsifying properties of animal and vegetable proteins | Proteins perform a vast array of functions in both the food and pharmaceutical industries, such as emulsification, foaming, encapsulation, viscosity enhancement and gelation."This functionality arises from the complex chemical make-up of these molecules.Proteins are of particular interest in food systems as emulsifiers... | The ultrasonic effect on the physicochemical and emulsifying properties of three animal proteins, bovine gelatin (BG), fish gelatin (FG) and egg white protein (EWP), and three vegetable proteins, pea protein isolate (PPI), soy protein isolate (SPI) and rice protein isolate (RPI), was investigated. Protein solutions (0.... |
34 | To target or not to target? Definitions and nomenclature for targeted versus non-targeted analytical food authentication | Historically, most analytical approaches for food authentication have been targeted towards single analytes, such as Sudan dyes in spices or melamine in milk powder.These targeted methods detect only one compound at a time and, therefore, often provide only limited information and insufficient consumer protection again... | The use of non-targeted analytical methods in food authentication has rapidly increased during the past decade. Non-targeted analyses are now used for a plethora of different food commodities but also across several scientific disciplines. This has brought together a mixture of analytical traditions and terminologies. ... |
35 | Assessment of industrial nitriding processes for fusion steel applications | 9Cr reduced activation ferritic martensitic steels are foreseen as the main structural steels for future fusion reactors beyond ITER.Development of these classes of materials started in the early to mid-1990s across several research associations in Europe, Japan and in the United States of America.Inspired by the class... | The 9Cr steels EUROFER and F82H-mod are the candidate materials for future fusion reactors. The extension of the operation limits including temperature, strength and toughness are still the scope of ongoing research. In a pulsed reactor operation, fatigue lifetime is one of the major properties for the steels. While th... |
36 | Combined Antiviral Therapy Using Designed Molecular Scaffolds Targeting Two Distinct Viral Functions, HIV-1 Genome Integration and Capsid Assembly | Human immunodeficiency virus type 1 infection continues to expand worldwide, despite all the efforts put into multiple therapeutic strategies.The current standard of care for HIV-infected patients is the highly active antiretroviral therapy, which successfully reduces the HIV plasma viral load to undetectable levels an... | Designed molecular scaffolds have been proposed as alternative therapeutic agents against HIV-1. The ankyrin repeat protein (AnkGAG 1D4) and the zinc finger protein (2LTRZFP) have recently been characterized as intracellular antivirals, but these molecules, used individually, do not completely block HIV-1 replication a... |
37 | Grassland futures in Great Britain – Productivity assessment and scenarios for land use change opportunities | Globally, grasslands are the dominant form of agriculture by land area, primarily utilised for the provision of feed for ruminants.In the United Kingdom, grasslands represent over two thirds of agricultural land area, broadly grouped into temporary, permanent and rough-grazing types.In 2015, UK grasslands supported 9.9... | To optimise trade-offs provided by future changes in grassland use intensity, spatially and temporally explicit estimates of respective grassland productivities are required at the systems level. Here, we benchmark the potential national availability of grassland biomass, identify optimal strategies for its management,... |
38 | Process optimisation of rotating membrane emulsification through the study of surfactant dispersions | Formulating dispersions of one liquid phase within another immiscible liquid remains an important area of research since these are readily incorporated within many foods, pharmaceutical, agrochemical and cosmetic products.Commonly cited examples from within the food industry include ice cream, mayonnaise and salad dres... | Abstract In this study, a rotating membrane emulsification setup incorporating a 6.1 μm pore diameter Shirasu porous glass membrane was used to produce oil-in-water emulsions. The processing conditions varied between 0.2 and 1.5 bar for the transmembrane pressure and shear rates at the membrane surface between 0.6 s<su... |
39 | Performance of invasive alien fountain grass (Pennisetum setaceum) along a climatic gradient through three South African biomes | The probability of success of an invasive species into a new habitat may result from the environmental and biotic factors that prevail in that habitat.These factors govern the rates of survival, establishment and spread of the invader in a new habitat.The success of invasive species control depends on detailed knowledg... | The knowledge of relative performance of plants across environmental gradients is critical for their effective management and for understanding future range expansion. Pennisetum setaceum is an invasive perennial grass found along roadsides and other disturbed sites in South Africa. The performance of this grass in res... |
40 | Abrogation of EMILIN1-β1 integrin interaction promotes experimental colitis and colon carcinogenesis | The ECM glycoprotein EMILIN-1 interacts with α4β1 , and the closely related α9β1 integrins, via the globular homotrimeric C-terminus gC1q domain, promoting cell adhesion and migration .In addition, EMILIN-1 provides an ECM cue for a correct homeostatic proliferation ; accordingly, targeted inactivation of the Emilin1 g... | Colon cancer is one of the first tumor types where a functional link between inflammation and tumor onset has been described; however, the microenvironmental cues affecting colon cancer progression are poorly understood. Here we demonstrate that the expression of the ECM molecule EMILIN-1 halts the development of AOM-D... |
41 | On input-output economic models in disaster impact assessment | In , disaster has been defined as the set of “consequences of a natural or man made hazard”.Considering the multi-faceted nature of primary triggers and outcomes encompassed by this definition, today one of the core research areas in disaster analysis is related to the assessment of resulting spillover effects in netwo... | During the last decades, input-output (I/O) economic models have assumed a prominent role in disaster impact analysis and resilience assessment. Rooted in general equilibrium theory and economic production theory, they catalyse attention on the distinction between direct economic losses and ripple effects that may be g... |
42 | Superconductivity in U-T alloys (T = Mo, Pt, Pd, Nb, Zr) stabilized in the cubic γ-U structure by splat-cooling technique | The large interest in stabilization of U-based alloys with a cubic γ-U structure has came first from the viewpoint of metallurgy.In the late 1970s massive research programs were launched in USA to develop the low enriched uranium fuels .The research showed that the U-Mo alloys with γ-U phase were the most promising can... | We succeed to retain the high-temperature (cubic) γ-U phase down to low temperatures in U-T alloys with less required T alloying concentration (T = Mo, Pt, Pd, Nb, Zr) by means of splat-cooling technique with a cooling rate better than 106 K/s. All splat-cooled U-T alloys become superconducting with the critical temper... |
43 | Moving (back) to greener pastures? Social benefits and costs of climate forest planting in Norway | Endre Kildal Iversen: Conceptualization, Data curation, Formal analysis, Methodology, Resources, Software, Validation, Visualization, Writing - original draft, Writing - review & editing.Henrik Lindhjem: Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Validation, Writing - or... | Norway is considering a national afforestation program for greenhouse gas sequestration on recently abandoned semi-natural pastureland. However, the program may have negative impacts on landscape aesthetics and biodiversity. We conducted a nation-wide choice experiment survey to estimate non-market values, combined wit... |
44 | Membrane-enclosed multienzyme (MEME) synthesis of 2,7-anhydro-sialic acid derivatives | Sialic acids constitute a structurally diverse family of nine-carbon acidic monosaccharides commonly found at the termini of the glycan chains on glycoproteins and glycolipids .N-Acetylneuraminic acid, N-glycolylneuraminic acid, and 2-keto-3-deoxy-D-glycero-D-galacto-nonulosonic acid are the three basic forms of sialic... | Naturally occurring 2,7-anhydro-alpha-N-acetylneuraminic acid (2,7-anhydro-Neu5Ac) is a transglycosylation product of bacterial intramolecular trans-sialidases (IT-sialidases). A facile one-pot two-enzyme approach has been established for the synthesis of 2,7-anhydro-sialic acid derivatives including those containing d... |
45 | Incidence of bifid uvula and its relationship to submucous cleft palate and a family history of oral cleft in the Brazilian population | Bifid uvula is a frequently observed anomaly in the general population.1,Its incidence varies according to racial groups.2,The incidence is higher in Indians and Mongols, average in Caucasians and less frequent in blacks.2,3,Bifid uvula is often regarded as a marker for submucous cleft palate although this relationship... | Introduction: Bifid uvula is a frequently observed anomaly in the general population and can be regarded as a marker for submucous cleft palate. Objective: In this study aimed to determine the frequency of bifid uvula and submucous cleft palate and their relationship with oral clefts in a Brazilian population. Methods:... |
46 | Data on trace element concentrations in coal and host rock and leaching product in different pH values and open/closed environments | Tables 1 and 2 show concentrations of major and trace elements in coal samples, and Tables 3 and 4 show concentrations in host rock samples after the first and second sampling and testing.Analysis of ICP-AES, ICP-MS were applied in the first the second testing, respectively.26 and 16 elements were analyzed in the first... | The data presented in this article are related to the research article entitled “Multivariate analysis of trace elements leaching from coal and host rock” [1]. During coal mining, coal and host rock undergo water-rock interaction, leading to release of trace elements to surface and ground water. The batch experiments w... |
47 | Correlates of unsuccessful smoking cessation among adults in Bangladesh | Worldwide, tobacco use is the leading cause of avoidable death.In each year, nearly 6 million peoples are killed by tobacco and if present pattern of tobacco use remains uncontrolled, > 8 million deaths will be caused annually by 2030.However, rates of smoking in developed countries is decreasing but in developing coun... | Having 21.9 million adult smokers, Bangladesh ranks among the top ten heaviest smoking countries in the world. Correlates of unsuccessful smoking cessation remain unknown. We aimed to identify the correlates of unsuccessful smoking cessation among adults in Bangladesh. We used data from the 2009 Global Adult Tobacco Su... |
48 | Dynamics in Transcriptomics: Advancements in RNA-seq Time Course and Downstream Analysis | Profiling of gene expression via high-throughput methods has been achieved for the first time in 1992 with the development of Differential Display protocols followed in 1995 by the implementation of complementary DNA microarrays .Subsequently, several other large scale techniques were developed like Serial Analysis of ... | Analysis of gene expression has contributed to a plethora of biological and medical research studies. Microarrays have been intensively used for the profiling of gene expression during diverse developmental processes, treatments and diseases. New massively parallel sequencing methods, often named as RNA-sequencing (RNA... |
49 | ICN_Atlas: Automated description and quantification of functional MRI activation patterns in the framework of intrinsic connectivity networks | The analysis and interpretation of functional MRI data activation patterns is usually performed in the framework of brain anatomy.In particular, activation clusters are usually described in terms of their extent and centre of gravity coordinates as defined in standard template spaces, e.g. MNI or Talairach.A variety of... | Generally, the interpretation of functional MRI (fMRI) activation maps continues to rely on assessing their relationship to anatomical structures, mostly in a qualitative and often subjective way. Recently, the existence of persistent and stable brain networks of functional nature has been revealed; in particular these... |
50 | Healthy ageing through internet counselling in the elderly (HATICE): a multinational, randomised controlled trial | Cardiovascular disease is the leading cause of morbidity and mortality worldwide, and is strongly related to unhealthy behaviours.1,2,Despite widespread preventive programmes, cardiovascular disease risk factors, including hypertension, hypercholesterolaemia, smoking, diabetes, unhealthy diet, obesity, and physical ina... | Background: Although web-based interventions have been promoted for cardiovascular risk management over the past decade, there is limited evidence for effectiveness of these interventions in people older than 65 years. The healthy ageing through internet counselling in the elderly (HATICE) trial aimed to determine whet... |
51 | Using SPIN for automated debugging of infinite executions of Java programs | The complexity of current software development is pushing programmers towards more automated analysis techniques, instead of the traditional interactive or postmortem debuggers.For instance, unit testing allows the execution of test cases against a program, checking parts of the code such as single methods or classes i... | This paper presents an approach for the automated debugging of reactive and concurrent Java programs, combining model checking and runtime monitoring. Runtime monitoring is used to transform the Java execution traces into the input for the model checker, the purpose of which is twofold. First, it checks these execution... |
52 | A catchment-scale method to simulating the impact of historical nitrate loading from agricultural land on the nitrate-concentration trends in the sandstone aquifers in the Eden Valley, UK | Excessive nitrate concentrations in water bodies can cause serious long-term environmental issues and threaten both economy and human health.Nitrate in freshwater remains an international problem.Elevated nitrate concentrations in groundwater are found across Europe.For example, the European Environment Agency reported... | Nitrate water pollution, which is mainly caused by agricultural activities, remains an international problem. It can cause serious long-term environmental and human health issues due to nitrate time-lag in the groundwater system. However, the nitrate subsurface legacy issue has rarely been considered in environmental w... |
53 | Temporal dynamics in local vehicle ownership for Great Britain | This study on vehicle ownership is set in the context of the island of Great Britain, which is part of the United Kingdom.Here vehicle ownership grew rapidly in the 20th century, as illustrated by the trends in Fig. 1 which show the shift in vehicle ownership levels since the early 1950s.After previous rapid increases ... | This article explores the stability of local vehicle ownership rates in Great Britain using the technique of spatial Markov chain analysis. Non-spatial Markov chain processes describe the transition of neighbourhoods through levels of ownership with no regard to their neighbourhood context. In reality however, how a ne... |
54 | Can integration of PV within UK electricity network be improved? A GIS based assessment of storage | Deployment of grid-connected photovoltaic systems in the United Kingdom has grown rapidly in the recent years."Cumulative PV installed capacity is now over 10GWp and PV contribution towards the UK's electricity generation has quickly grown from 0.1% in 2011 to 2.2% in 2015.Typically installed within the network much cl... | This paper analyses the potential of distributed storage to mitigate impacts of embedded PV generation on the distribution grid by improving local balance between generation and demand, thereby enabling higher levels of PV penetration. In particular it looks at the potential of storage to: 1. reduce impacts on power fl... |
55 | mTOR-S6K1 pathway mediates cytoophidium assembly | CTP not only serves as the building blocks for nucleic acid synthesis, but also contributes to the synthesis of membrane phospholipids and protein sialylation.Low intracellular concentration makes CTP one of the rate-limiting molecules for nucleic acid biosynthesis and other CTP-dependent events.Therefore, understandin... | CTP synthase (CTPS), the rate-limiting enzyme in de novo CTP biosynthesis, has been demonstrated to assemble into evolutionarily conserved filamentous structures, termed cytoophidia, in Drosophila, bacteria, yeast and mammalian cells. However, the regulation and function of the cytoophidium remain elusive. Here, we pro... |
56 | The Structure of a Conserved Domain of TamB Reveals a Hydrophobic β Taco Fold | In Gram-negative bacteria, the outer membrane serves as a highly selective permeability barrier, protecting bacterial cells from a hostile external environment, while allowing import of the nutrients required for survival and growth.In addition, the OM forms the interface between the bacteria and its external environme... | The translocation and assembly module (TAM) plays a role in the transport and insertion of proteins into the bacterial outer membrane. TamB, a component of this system spans the periplasmic space to engage with its partner protein TamA. Despite efforts to characterize the TAM, the structure and mechanism of action of T... |
57 | Whole genome sequencing uses for foodborne contamination and compliance: Discovery of an emerging contamination event in an ice cream facility using whole genome sequencing | Whole genome sequencing has been used to provide detailed characterization of foodborne pathogens.Genomes comprising diverse groups of pathogenic genus and species including Listeria monocytogenes, E. coli, Salmonella, Campylobacter and Vibrio have provided insight into the genetic make-up and relatedness of these path... | We review how FDA surveillance identifies several ways that whole genome sequencing (WGS)improves actionable outcomes for public health and compliance in a case involving Listeria monocytogenes contamination in an ice cream facility. In late August 2017 FDA conducted environmental sampling inside an ice cream facility.... |
58 | Lipid derivatives activate GPR119 and trigger GLP-1 secretion in primary murine L-cells | Glucagon-like peptide-1 has multiple anti-diabetic effects, most notably enhancing insulin secretion, suppressing glucagon release and slowing gastric emptying .Current incretin-based therapies focus on preventing the breakdown of GLP-1 by dipeptidyl peptidase-IV or administrating GLP-1 mimetics .The benefits of increa... | Aims/hypothesis Glucagon-like peptide-1 (GLP-1) is an incretin hormone derived from proglucagon, which is released from intestinal L-cells and increases insulin secretion in a glucose dependent manner. GPR119 is a lipid derivative receptor present in L-cells, believed to play a role in the detection of dietary fat. Thi... |
59 | t-Distributed Stochastic Neighbor Embedding (t-SNE): A tool for eco-physiological transcriptomic analysis | Key to assessing the health of an ecosystem is to know the physiological states of its inhabitants.Physiology governs progressions through life cycles, adaptiveness to environment including ability to cope with stressors, and reproductive success.But the “physiological state” of an organism is not easily determined bec... | High-throughput RNA sequencing (RNA-Seq) has transformed the ecophysiological assessment of individual plankton species and communities. However, the technology generates complex data consisting of millions of short-read sequences that can be difficult to analyze and interpret. New bioinformatics workflows are needed t... |
60 | Renewable transitions and the net energy from oil liquids: A scenarios study | The necessity of a global transition to sources of renewable energy production, or Renewable Transition, has now a relevant place in the political agenda as illustrated by the recent commitment of G7 countries and the EU for a future sustainable energy security supply .But even before this commitment, the last years ha... | We use the concept of Energy Return On energy Invested (EROI) to calculate the amount of the available net energy that can be reasonably expected from World oil liquids during the next decades (till 2040). Our results indicate a decline in the available oil liquids net energy from 2015 to 2040. Such net energy evaluati... |
61 | Antioxidant and free radical scavenging activities of taxoquinone, a diterpenoid isolated from Metasequoia glyptostroboides | Overproduction of free radicals and reactive oxygen species has been confirmed in a human body due to the perturbation of various metabolic reactions.Free radicals and ROS are generated through normal reactions within the body during respiration in aerobic organisms which can exert diverse functions like signaling role... | Nowadays, there is an upsurge of interest on finding effective phyto-constituents as new sources of natural antioxidants for using in food and pharmaceutical preparations. However, this study was carried out to investigate the antioxidant and free radical scavenging efficacy of a biologically active diterpenoid compoun... |
62 | Epifaunal communities across marine landscapes of the deep Chukchi Borderland (Pacific Arctic) | Deep-sea regions occupy roughly half of the Arctic Ocean area, yet the understanding of Arctic deep-sea biodiversity still remains extremely limited.Recent scientific programs such as the International Polar Year 2007–2009, Census of Marine Life, and studies at the HAUSGARTEN, a biological long-term deep-sea observator... | Epifaunal communities from the poorly studied Arctic deep sea of the Chukchi Borderland region were investigated to: (1) determine differences in community structure among ridges, plateau with pockmarks, and much deeper basins as three main habitat types, (2) analyse the environmental factors that might shape these com... |
63 | Energy-weighted dynamical scattering simulations of electron diffraction modalities in the scanning electron microscope | Electron diffraction techniques in the scanning electron microscope are established and versatile tools for microstructural investigation of crystalline materials.The strong and complex local interactions of electrons with crystalline matter offer a plethora of information about the crystal structure and material prope... | Transmission Kikuchi diffraction (TKD) has been gaining momentum as a high resolution alternative to electron back-scattered diffraction (EBSD), adding to the existing electron diffraction modalities in the scanning electron microscope (SEM). The image simulation of any of these measurement techniques requires an energ... |
64 | Linking naturally and unnaturally spun silks through the forced reeling of Bombyx mori | Silks are fibrous proteins spun by various arthropods for a variety of natural functions .The silk of the mulberry silkworm Bombyx mori is of particular scientific interest, not least because its industrial-scale commercial production makes it an important model material for protein and polymer research .The silks in t... | The forced reeling of silkworms offers the potential to produce a spectrum of silk filaments, spun from natural silk dope and subjected to carefully controlled applied processing conditions. Here we demonstrate that the envelope of stress-strain properties for forced reeled silks can encompass both naturally spun cocoo... |
65 | Perception and self-assessment of digital skills and gaming among youth: A dataset from Spain | The present dataset in this paper was collected in May 2017.The raw data are available in Excel and SPSS format.The main data file spreadsheet accompanying this article contains 1012 rows of data, with the columns containing variables derived from responses to the survey.The survey includes 15 questions followed by dif... | The present article offers a dataset of how young Spanish people perceive and evaluate their digital skills, showing the confidence level of their Social skills, Mobile skills, Information/navigation skills, Operational skills, and Creative skills. It also provides data on the use and the typology of video games in whi... |
66 | Calibrating Mars Orbiter Laser Altimeter pulse widths at Mars Science Laboratory candidate landing sites | Accurate estimates of surface roughness allow for quantitative comparisons of surface descriptions leading to improved understanding of formation processes, improved identification of landing site hazards and calibration of radar returns, and more accurate estimates of aerodynamic roughness used in terrain–atmosphere i... | Accurate estimates of surface roughness allow quantitative comparisons between planetary terrains. These comparisons enable us to improve our understanding of commonly occurring surface processes, and develop a more complete analysis of candidate landing and roving sites. A (secondary) science goal of the Mars Orbiter ... |
67 | Time-of-use and time-of-export tariffs for home batteries: Effects on low voltage distribution networks | With the rollout of smart meters in the UK, along with the regulator’s desire to mandate half-hourly settlement of all electricity consumers based on their actual half-hourly consumption , there is considerable interest in the development of time-of-use tariffs.These roughly align domestic electricity prices with deman... | Time-of-use electricity tariffs are gradually being introduced around the world to expose consumers to the time-dependency of demand, however their effects on peak flows in distribution networks, particularly in areas with domestic energy storage, are little understood. This paper presents investigations into the impac... |
68 | The blink reflex magnitude is continuously adjusted according to both current and predicted stimulus position with respect to the face | The eye blink elicited by electrical stimulation of the median nerve at the wrist hand-blink reflex is a defensive reflex subserved by an entirely subcortical circuit at brainstem level.Human electromyographic recordings from the orbicularis oculi muscles show that the HBR consists of a bilateral response with an onset... | The magnitude of the hand-blink reflex (HBR), a subcortical defensive reflex elicited by the electrical stimulation of the median nerve, is increased when the stimulated hand is close to the face ('far-near effect'). This enhancement occurs through a cortico-bulbar facilitation of the polysynaptic medullary pathways su... |
69 | Autologous mesenchymal stem cell application for cartilage defect in recurrent patellar dislocation: A case report | Recurrent patellar dislocation is a repeated dislocation that follows from an initial episode of minor trauma dislocation .Conservative management gives a minimal result in re-dislocation, with persistent symptoms of anterior knee pain, instability and activity limitation.Meanwhile, there is no gold standard treatment ... | Introduction: Recurrent patellar dislocation can lead to articular cartilage injury. We report a 21-year old male with left patella instability and articular cartilage defect. Presentation of case: A 21-year-old male presented with left patellar instability and pain. Knee range of motion (ROM) was limited when patella ... |
70 | Neural Profile of Callous Traits in Children: A Population-Based Neuroimaging Study | This cross-sectional study was embedded in the Generation R Study, a prospective population-based cohort from Rotterdam, the Netherlands.Study protocols were approved by the local ethics committee, and written informed consent and assent was obtained from all parents and children, respectively.At mean age 10 years in c... | Background: Callous traits during childhood, e.g., lack of remorse and shallow affect, are a key risk marker for antisocial behavior. Although callous traits have been found to be associated with structural and functional brain alterations, evidence to date has been almost exclusively limited to small, high-risk sample... |
71 | Are BVS suitable for ACS patients? Support from a large single center real live registry | Drug-eluting stents are the first choice devices in percutaneous coronary interventions.Despite recent advantages, shortcomings related to the use of DES still are present such as delayed arterial healing, late stent thrombosis, neo-atherosclerosis and hypersensitivity reactions to the polymer .To overcome these limita... | Objectives To investigate one-year outcomes after implantation of a bioresorbable vascular scaffold (BVS) in patients presenting with acute coronary syndrome (ACS) compared to stable angina patients. Background Robust data on the outcome of BVS in the setting of ACS is still scarce. Methods Two investigator initiated, ... |
72 | Hydrophobically Modified siRNAs Silence Huntingtin mRNA in Primary Neurons and Mouse Brain | RNA interference is a highly efficient gene-silencing mechanism in which a small interfering RNA binds a target mRNA, guiding mRNA cleavage via an RNA-induced silencing complex.1,2,This biological phenomenon is widely used as a genetic tool in biomedical research.Advances in RNA chemistry have expanded siRNA applicatio... | Applications of RNA interference for neuroscience research have been limited by a lack of simple and efficient methods to deliver oligonucleotides to primary neurons in culture and to the brain. Here, we show that primary neurons rapidly internalize hydrophobically modified siRNAs (hsiRNAs) added directly to the cultur... |
73 | Trace metal distributions in sulfide scales of the seawater-dominated Reykjanes geothermal system: Constraints on sub-seafloor hydrothermal mineralizing processes and metal fluxes | Recent years have seen a rapid growth in demand for specific elements and metals that are commonly present in only trace quantities in mined ores and recovered only as by-products of other metals.Some of these metals are found in ancient volcanogenic massive sulfide deposits that are mined mostly for Cu, Zn and Pb, and... | Mineral precipitation in the seawater-dominated Reykjanes geothermal system on the Mid-Atlantic Ridge, Iceland is caused by abrupt, artificially induced, pressure and temperature changes as deep high-temperature liquids are drawn from reservoir rocks up through the geothermal wells. Sulfide scales within these wells re... |
74 | Innovative technologies to manage aflatoxins in foods and feeds and the profitability of application – A review | Food security is effectually achieved when the food pillars, including food availability, food access, food utilization, and food stability are at levels that allow all people at all times to have physical and economic access to affordable, safe, and nutritious food to meet the requirement for an active and a healthy l... | Aflatoxins are mainly produced by certain strains of Aspergillus flavus, which are found in diverse agricultural crops. In many lower-income countries, aflatoxins pose serious public health issues since the occurrence of these toxins can be considerably common and even extreme. Aflatoxins can negatively affect health o... |
75 | Cutaneous Nod2 Expression Regulates the Skin Microbiome and Wound Healing in a Murine Model | Skin is colonized by diverse microorganisms, collectively termed the skin microbiome.Recent methodological advances in high-throughput sequencing have shown the complexity of microorganisms associated with skin and have begun to directly implicate a microbial imbalance, a so-called dysbiosis, in skin health and disease... | The skin microbiome exists in dynamic equilibrium with the host, but when the skin is compromised, bacteria can colonize the wound and impair wound healing. Thus, the interplay between normal skin microbial interactions versus pathogenic microbial interactions in wound repair is important. Bacteria are recognized by in... |
76 | Memtein: The fundamental unit of membrane-protein structure and function | Membrane protein structural and functional integrity depends on a layer of lipids that surround much of their surface.However, available membrane protein structures typically lack this biological lipid layer, despite its requirement for their correct operation.In fact, there is no word for the biologically intact unit ... | The concept of a memtein as the minimal unit of membrane function is proposed here, and refers to the complex of a membrane protein together with a continuous layer of biological lipid molecules. The elucidation of the atomic resolution structures and specific interactions within memteins remains technically challengin... |
77 | SOX7 expression is critically required in FLK1-expressing cells for vasculogenesis and angiogenesis during mouse embryonic development | The development of the vascular system involves a complex array of processes necessary to regulate the dynamic nature of the emerging vascular network.During development, the first blood vessels form in the extra-embryonic yolk sac via vasculogenesis, which initiates following the formation of blood islands from mesode... | The transcriptional program that regulates the differentiation of endothelial precursor cells into a highly organized vascular network is still poorly understood. Here we explore the role of SOX7 during this process, performing a detailed analysis of the vascular defects resulting from either a complete deficiency in S... |
78 | Introducing nature-based solutions into urban policy – facts and gaps. Case study of Poznań | Cities, as places of population concentration and high economic potential, with diverse natural conditions, face many challenges connected with the simultaneous provision of a high quality of life for the inhabitants and the resilience of the city to human pressure and extreme events, including changing climatic condit... | Cities often don't appreciate the benefits of green infrastructure (GI) enough. To recognise the extent to which green infrastructure and nature-based solutions (NbS) are present in the urban policy, we conducted a review of planning, strategic and programming documents of Poznań City as a Case Study. The study is aime... |
79 | Amelioration of thyroid dysfunction by magnesium in experimental diabetes may also prevent diabetes-induced renal impairment | Diabetes and thyroid disorders are common endocrine disorders that have been shown to mutually influence each other .Studies have shown that thyroid hormones contribute to the regulation of carbohydrate metabolism and pancreatic function .Thyroid hormones have also been observed to directly control insulin secretion wi... | Background: Diabetes mellitus has been reported to cause thyroid dysfunction, which may also impair renal function. Magnesium has been reported to exert ameliorative effects in diabetes mellitus. This study investigated thyroid and renal functions in experimental type-2-diabetic Wistar rats. Methods: Experimental type-... |
80 | Mortality of people with chronic fatigue syndrome: A retrospective cohort study in England and Wales from the South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLaM BRC) Clinical Record Interactive Search (CRIS) Register | Chronic fatigue syndrome is an illness characterised by persistent or relapsing fatigue of a debilitating nature, which is present for at least 6 months, in addition to at least four symptoms from a range including memory loss, poor concentration, joint pain, and tender glands.1,2,Patients with chronic fatigue syndrome... | Background Mortality associated with chronic fatigue syndrome is uncertain. We investigated mortality in individuals diagnosed with chronic fatigue syndrome in secondary and tertiary care using data from the South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLaM BRC) Clinical Record Interactive... |
81 | How do cities support electric vehicles and what difference does it make? | It is generally agreed that the global atmospheric concentrations of Greenhouse Gases such as CO2 have increased markedly as a result of human activities since the industrial revolution and humans are clearly influencing the climate system.The largest growth in anthropogenic GHG emissions between 1970 and 2004 was attr... | Many cities publish climate change mitigation strategies and other policy measures to support the wide spread uptake of Electric Vehicles (EVs). This paper investigates the effectiveness of these strategies and the provision of infrastructures in 30 UK cities, with a specific emphasis on those strategies that are withi... |
82 | Characterization of sheep pox virus vaccine for cattle against lumpy skin disease virus | Lumpy skin disease virus, sheep pox virus and goat pox virus comprise the Capripoxvirus genus within the Poxviridae family.Sheep pox and goat pox are endemic in northern and central Africa and in large parts of Asia.Lumpy skin disease occurs across Africa and has recently been aggressively spreading in the Middle East,... | Lumpy skin disease is of significant economic impact for the cattle industry in Africa. The disease is currently spreading aggressively in the Near East, posing a threat of incursion to Europe and Asia. Due to cross-protection within the Capripoxvirus genus, sheep pox virus (SPPV) vaccines have been widely used for cat... |
83 | Performance assessment of chemical mechanical planarization wastewater treatment in nano-electronics industries using membrane distillation | In the 1980s chemical mechanical planarization was introduced at IBM for integrated circuit fabrication, later emerging as a crucial polishing technique in nano-electronics industries .In CMP processes abrasive materials are used in combination with ultrapure water and a range of chemical additives: complexing agents ;... | Wastewater from chemical mechanical planarization (CMP) processes in nano-electronics industries must be treated properly in order to fulfil local and international environmental regulations. This study is focused on a performance assessment of membrane distillation (MD) technology for CMP wastewater treatment. A new p... |
84 | Vaccination program in a resource-limited setting: A case study in the Philippines | Human resources are an integral part of every healthcare system .However, in low- and middle-income countries, human resources for health are often limited, which impacts both the access to and quality of healthcare .The shortage of healthcare workers can be due to different factors such as low production capacity for ... | Objective Implementing national-level vaccination programs involves long-term investment, which can be a significant financial burden, particularly in resource-limited settings. Although many studies have assessed the economic impacts of providing vaccinations, evidence on the positive and negative implications of huma... |
85 | Effects of agricultural mechanization on economies of scope in crop production in Nigeria | Agricultural mechanization is an integral part of agricultural development, since it is commonly characterized by scale-effects that allow for specialization.Empirical evidence is, however, scarce on how mechanization affects other aspects of agricultural production like economies of scope.EOS, the cost advantage of pr... | Agricultural mechanization has often been associated with scale-effects and increased specialization. Such characterizations, however, fail to explain how mechanization may grow in Africa where production environments are heterogeneous even within a farm household, and crop diversification may help in mitigating risks.... |
86 | Cross-sectional variations of white and grey matter in older hypertensive patients with subjective memory complaints | Subjective cognitive impairment is common in the elderly, and may serve as a symptomatic indicator of a precursor stage of Alzheimer's dementia, even if subtle cognitive decline is difficult to detect on standardized cognitive testing.While this condition is not considered to be a definite neurodegenerative process suc... | Mild cognitive impairment and Alzheimer's dementia involve a grey matter disease, quantifiable by 18F-Fluorodeoxyglucose positron emission tomography (FDG-PET), but also white matter damage, evidenced by diffusion tensor magnetic resonance imaging (DTI), which may play an additional pathogenic role. This study aimed to... |
87 | Challenges in integrative approaches to modelling the marine ecosystems of the North Atlantic: Physics to fish and coasts to ocean | The North Atlantic Ocean and its contiguous shelf seas provide a diverse range of goods and services to mankind.However, global climate change will lead to substantial changes in the physical conditions of the basin.At the same time, combinations of direct anthropogenic drivers impact at both an organismal and populati... | It has long been recognised that there are strong interactions and feedbacks between climate, upper ocean biogeochemistry and marine food webs, and also that food web structure and phytoplankton community distribution are important determinants of variability in carbon production and export from the euphotic zone. Nume... |
88 | Characterization of cracks formed in large flat-on-flat fretting contact | Micrometer-level relative movement between contacts under normal loading may lead to fretting fatigue and severe damage in machine components.Cyclic fretting movement causes surface degradation and wear and promotes crack nucleation.Cracks may nucleate even at relatively low nominal cyclic stress levels.It is difficult... | Fretting fatigue may lead to severe damage in machines. Adhesive material transfer spots in millimeter scale have previously been observed on fretted surfaces, which have been related to cracking. In this study, fretting-induced cracks formed in a large annular flat-on-flat contact are characterized. Optical and scanni... |
89 | Attention deficit hyperactivity disorder symptoms as antecedents of later psychotic outcomes in 22q11.2 deletion syndrome | 22q11.2 Deletion Syndrome is diagnosed typically on the basis of its clinical presentation together with laboratory evidence of a deletion or Copy Number Variant at band q11.2 on chromosome 22.Approximately 1 in 4000 individuals are affected by 22q11.2DS, rendering this the most common chromosomal microdeletion syndrom... | Individuals with 22q11.2 Deletion Syndrome (22q11.2DS) are at substantially heightened risk for psychosis. Thus, prevention and early intervention strategies that target the antecedents of psychosis in this high-risk group are a clinical priority. Attention Deficit Hyperactivity Disorder (ADHD) is one the most prevalen... |
90 | Surface-based 3D measurements of small aeolian bedforms on Mars and implications for estimating ExoMars rover traversability hazards | The surface of Mars hosts various types of aeolian bedforms, from small wind-ripples of centimetre-scale wavelength, through larger decametre-scale “Transverse Aeolian Ridges” to kilometre-scale dunes.To date, all mobile Mars surface-missions have encountered recent aeolian bedforms of one kind or another, despite bein... | Recent aeolian bedforms comprising loose sand are common on the martian surface and provide a mobility hazard to Mars rovers. The ExoMars rover will launch in 2020 to one of two candidate sites: Mawrth Vallis or Oxia Planum. Both sites contain numerous aeolian bedforms with simple ripple-like morphologies. The larger e... |
91 | Next generation in vitro liver model design: Combining a permeable polystyrene membrane with a transdifferentiated cell line | The use of membranes as cell scaffolds is of key interest in the development of in vitro drug screening assays.Cells cultured in membrane bioreactors experience a more in vivo-like environment than those in traditional two-dimensional cell culture .Culturing cells under physiologically relevant conditions can create mo... | Herein we describe the manufacture and characterisation of biocompatible, porous polystyrene membranes, suitable for cell culture. Though widely used in traditional cell culture, polystyrene has not been used as a hollow fibre membrane due to its hydrophobicity and non-porous structure. Here, we use microcrystalline so... |
92 | Miniaturized whole-cell bacterial bioreporter assay for identification of quorumsensing interfering compounds | Quorum sensing is a bacterial communication system that coordinates cooperative behaviors in bacteria in a population density-dependent manner by means of small chemical signals.QS has been shown to affect virulence factor production and biofilm formation in several bacterial species, including clinically relevant huma... | The continuing emergence and spread of antibiotic-resistant bacteria is worrisome and new strategies to curb bacterial infections are being sought. The interference of bacterial quorum sensing (QS) signaling has been suggested as a prospective antivirulence strategy. The AI-2 QS system is present in multiple bacterial ... |
93 | Developing benders decomposition algorithm for a green supply chain network of mine industry: Case of Iranian mine industry | Over the recent decades with rapid industrialization and expansion in production, consumption and trading levels in the world, the necessity for supply chain management in several industries has increased.Manifold factors influence the necessity to utilize SCM, importantly costs and environmental issues.Firms face chal... | This paper attempts to design a three-echelon supply chain network for mine industry considering suppliers, manufacturing centers and distributors with different kinds of vehicles. A multi-objective mixed integer programming model is proposed to minimize transportation costs, shortage costs, purchase costs, production ... |
94 | Associations between abuse/neglect and ADHD from childhood to young adulthood: A prospective nationally-representative twin study | Childhood maltreatment including abuse and neglect can affect between 2.5–32% of children worldwide and is an important risk factor for the development of internalising and externalising psychopathology in adolescence and adulthood.Being a victim of maltreatment at a young age is related to symptoms of psychiatric diso... | Child maltreatment has consistently been found to be associated with attention deficit/hyperactivity disorder (ADHD). However, the robustness of this association and the direction of the link between maltreatment and ADHD remain unclear. We used data from the Environmental Risk (E-Risk) Longitudinal Twin Study, a cohor... |
95 | Multi-part segmentation for porcine offal inspection with auto-context and adaptive atlases | Segmentation of non-rigid biological objects into their constituent parts presents various challenges.Here we address a segmentation task in which parts are organs in body images captured at abbatoir.This constitutes one stage in an envisaged on-site system for screening of pathologies; these are characteristically org... | Extensions to auto-context segmentation are proposed and applied to segmentation of multiple organs in porcine offal as a component of an envisaged system for post-mortem inspection at abbatoir. In common with multi-part segmentation of many biological objects, challenges include variations in configuration, orientatio... |
96 | The impact of multi-layered porosity distribution on the performance of a lithium ion battery | A number of recent studies have highlighted that lithium ion batteries have become the dominant battery technology for many automotive and transport applications.One of the primary reasons for their adoption is their relatively high energy density and high power density compared to alternative battery technologies.Howe... | This study investigates the impact of a multi-layered porosity profile on the electrical and thermal performance of a lithium-ion battery. Consideration is given to key attributes of the battery, namely its specific power and energy and the temperature distribution that may generated throughout the cell under electrica... |
97 | Poisoning effects of H2S and HCl on the naphthalene steam reforming and water-gas shift activities of Ni and Fe catalysts | Syngas obtained during biomass/municipal solid waste gasification is mainly a mixture of carbon monoxide, carbon dioxide, hydrogen, methane and nitrogen, which can be utilized for electric power generation or liquid fuel synthesis .The biomass- and MSW-derived syngas, however, contains significant concentrations of imp... | H2S and HCl are common impurities in raw syngas produced during gasification of biomass and municipal solid waste. The purpose of this study was to investigate the poisoning effect of H2S and HCl on synthesized and commercial catalysts during steam reforming of naphthalene. Four synthesized catalysts with different loa... |
98 | Service growth in product firms: Past, present, and future | Service growth in product firms has become one of the most active service research domains, to the point that it has been identified as a strategic research priority.This domain is concerned with product firms shifting from developing, manufacturing, and selling products to innovating, selling, and delivering services.... | Service growth in product firms is one of the most active service research domains and is open to a variety of conceptualizations. This article provides a critical inquiry into the past, present, and future of the research domain. The evolution of the research on service growth is discussed in two phases: (1) setting t... |
99 | Political economy of fiscal unions | One of the most intriguing questions of economics concerns the conditions under which deeper integration is possible and the circumstances that make integration fail.And fail it does remarkably often: more than 100 new countries emerged in the course of the 20th century alone.Clearly, political and cultural motives suc... | Fiscal unions often use fiscal transfers to counter asymmetric shocks, but such transfers may be politically controversial. I present a model of a two-region fiscal union with region-specific shocks where the threat of secession imposes a limit on fiscal redistribution between regions. I show that both correlation of s... |
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