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Messaging aside, what's in the VS pipeline, according to Schlimmer?
Like just about every Microsoft product these days, VS 10 is going to get the Software+Services treatment, Schlimmer continued. The VS10 release will see Help based on Live Search; integrate community ratings; and add support for multiple-machine synchronization via Live Mesh and Live ID. There are plans to add instant messaging some time later to facilitate small-team communication, as well as "multi-user editing" of shared source code.
Microsoft has not provided a public ship-date target for VS10 (that I know of... anyone else?). If the company sticks to its every-two- to three-year schedule, it's probably due in 2009 or 2010, as VS 2008 was released to manufacturing at the end of 2007.
Boot from PCIe SSD GA-X58A-UD3R?
Gigabyte GA-X58A-UD7 (Rev 2.0) and Xeon Processor to support ECC Memory?
Audio front panel in Gigabyte GA-MA69VM-s2. The name wires are different?
Gigabyte Gaming 7 (GA-Z97X-Gaming 7) BIOS 1 not working.
Problems with Gigabyte GA-945GCM-S2L please help!!
Chairman of Icahn Enterprises Carl Icahn participates in a panel discussion at the New York Times 2015 DealBook Conference at the Whitney Museum of American Art on November 3, 2015 in New York City.
Activist investors are going after Bristol-Myers Squibb, a drugmaker with a $93 billion market cap.
First, Jana Partners pressured the drugmaker into adding three new board members and announcing a stock buyback deal. Jana became a shareholder in BMS in the fourth quarter of 2016.
Now, The Wall Street Journal reports that billionaire Carl Icahn has invested in the company, reportedly because he thinks the company's drug portfolio could be ripe for a takeover.
That's left the industry buzzing about which company could be a potential buyer. Analysts have said that the company could make for a good acquisition, but more data on its cancer immunotherapy drugs may need to come in first.
Given Bristol-Myers Squibb market capitalization, any deal would likely be worth more than $100 billion, as takeover offers usually occur at a premium to the existing share price.
That would make it a blockbuster transaction.
BMS has been leading the charge in cancer immunotherapy, a new kind of cancer treatment. Unlike chemotherapy, which involves administering powerful drugs that kill both cancerous and healthy cells (most healthy cells can repair themselves), immunotherapies harness the power of the immune system to help it identify and knock out just the cancerous cells.
BMS's drug, ipilimumab (Yervoy), was the first checkpoint inhibitor (a kind of cancer immunotherapy drug that essentially helps the immune system release its brake and go after tumor cells it might normally miss) to get approved in the US in 2011 for melanoma. In 2014, BMS's anti-PD-1 checkpoint inhibitor nivolumab (Opdivo), got approved.
Investors expect new cancer immunotherapies to make billions of dollars in sales over the the next few years. As of the fourth quarter, sales of Opdivo were $1.3 billion.
These checkpoint inhibitors are an integral part of cancer immunotherapy treatments. Trials are currently underway to see if combinations of two or even three of these drugs could lead to better response rates, or if combining an immunotherapy drug with chemotherapy could work better than just one or the other. For companies that don't have a checkpoint inhibitor, that means partnering up, often with BMS, to run these trials.
But BMS isn't the only one in the checkpoint inhibitor field. It's been facing increasing pressure from competitors, including Merck and Roche.
The company has also gotten bad trial news, which has sent the stock price falling. In August 2016, Opdivo failed a key lung cancer trial. At the same time, Merck's anti-PD-1 drug succeeded in its version of the trial. Things didn't get much better in October when the full data was presented at a medical conference.
And in January, BMS said that it wouldn't go for an accelerated approval for the combination of its two immunotherapy drugs as an initial treatment for lung cancer. This helped Merck secure its lead in lung cancer combination treatments.
Beyond cancer immunotherapy, BMS also makes the bloodthinner Eliquis in collaboration with drug giant Pfizer, and treatments for hepatitis C and rheumatoid arthritis. It's also one of a growing number of companies going after NASH, a type of liver disease that's estimated to affect about 16 million Americans.
Jonathan Darsky, right, prepares to put a pizza in the oven in Del Popolo, a mobile pizzeria housed in a 25ft. shipping container, on Thursday, June 7, 2012 at Mint Plaza in San Francisco, Calif.
Del Popolo is no ordinary food truck. The 20-foot shipping container holds the pizza oven, and one side has been completely carved out and outfitted with full window doors.
Pizzas baked in Jonathan Darsky's Del Popolo, a mobile pizzeria housed in a 25ft. shipping container, are seen on Thursday, June 7, 2012 at Mint Plaza in San Francisco, Calif.
Sunny Kim, left, and her dog, Moody, had pizza at Jonathan Darsky's Del Popolo, a mobile pizzeria housed in a 25ft. shipping container, on Thursday, June 7, 2012 at Mint Plaza in San Francisco, Calif.
Niki Shelley hands a pizza to a customer at Jonathan Darsky's Del Popolo, a mobile pizzeria housed in a 25ft. shipping container, on Thursday, June 7, 2012 at Mint Plaza in San Francisco, Calif.
A sign on Jonathan Darsky's Del Popolo, a mobile pizzeria housed in a 25ft. shipping container, announces the opening time on Thursday, June 7, 2012 at Mint Plaza in San Francisco, Calif.
Niki Shelley prepares to hand pizzas to customers at Jonathan Darsky's Del Popolo, a mobile pizzeria housed in a 25ft. shipping container, on Thursday, June 7, 2012 at Mint Plaza in San Francisco, Calif.
Jon Darsky has made his name with his one-of-a-kind pizza truck, Del Popolo, which rolled out in the Bay Area about three years ago.
Actually, calling Del Popolo a pizza truck is a bit of a misnomer; it’s really a beast of a mobile pizzeria: a 14-ton converted heavy-duty truck, a 5,000-pound wood-fired oven, a shipping container shell, a constant line of customers, and perhaps most importantly, some of the best pies in town.
Later this year, Darsky will also have a permanent home for his Neapolitan-inspired pizza.
Darsky confirms to Scoop that he has secured a brick-and-mortar location for Del Popolo. At his pizzeria — to be located at 855 Bush Street, between Taylor and Mason — Darsky will serve pizza, of course. But with the expanded space, he will also expand the menu to includes salad, fried rice balls, and other antipasti.
The truck will continue as usual. The pizzeria is slated to open later this year. Be excited.
Western Forum for Migrant and Community Health – Now Accepting Abstracts!
Planning for the 2018 Western Forum for Migrant and Community Health is in full swing at NWRPCA! The event will take place in beautiful Seattle, Washington from February 22-24, 2018. The Western Forum features workshops and breakout sessions featuring programs, policies, and other initiatives aimed to improve access to care and health outcomes for the underserved.
The 2018 Western Forum will also feature a poster session sponsored by the Pacific Northwest Agricultural Safety and Health Center scheduled for Thursday, February 22nd from 5:30-6:30pm. To learn more about the poster session and submission details, click here.
To learn more about past Western Forum, please contact Jessica Burkard, NWRPCA's Community Health Improvement Project Manager, for more information.
*Event start and end times have not been announced. Please disregard times specified here.
The Terre Haute Police Department is looking for information on a robbery that happened on Oct. 6.
TERRE HAUTE, Ind. (WTHI) - The Terre Haute Police Department is looking for information on a robbery that happened on Oct. 6.
THPD reports the robbery happened at Mr. M's Liquor located at 25th and College.
This happened on Oct. 6 just before 9:45 p.m.
If you have any information on this crime and/or the suspect shown in the photos, please call the Terre Haute Police Department at (812) 238-1661 or contact their Facebook page and/or Twitter.
Apr. 21 7:13 PM PT8:13 PM MT9:13 PM CT10:13 PM ET2:13 GMT10:13 7:13 PM MST8:13 PM CST9:13 PM EST6:13 UAE (+1)22:13 ET23:13 BRT - Barclay Goodrow had 16:03 of ice time in the Sharks' 2-1 win over the Golden Knights on Sunday. He didn't take a shot and had a plus-minus of even for the game.
Portera Systems has been something of a trailblazer in the application services business, focusing on a vertical market — professional services — before vertical markets were cool and becoming the first ASP to offer services based on Oracle software. Now, the company is pushing in a new direction: south. "About 15 percent of our business in recent quarters has been coming from international markets, and Latin America is ramping faster than Europe," says Portera CEO Gary Steele. Portera opened a sales office in Mexico City in the third quarter of 2000 and is working with services firm Azurian in Brazil, Chile and Costa Rica. "There is a perception in the ASP community that international markets are nascent and immature, but we are seeing a strong reception across diverse customers," Steele says. Porteras No. 1 selling point abroad has been letting customers avoid the expense and complexity of building their own information technology infrastructure.
"People ask us all the time about licensing and owning and managing our software, but we dont have shrink-wrapped CD-ROMs," says Graeme Jarvis, director of software engineering at StorageNetworks. The company is scheduled to announce today, April 9, new software services to make its managed storage services more accessible. Customers like the way StorageNetworks gets diverse storage devices to work together, but a portal product and other applications arent available for sale. "We use software to leverage our services," Jarvis says. StorageNetworks does offer to manage an enterprises existing storage assets as part of its service.
In a move reflecting the rise of new media over old, the education software maker Riverdeep Holdings Limited announced last week its $3.4 billion purchase of the Houghton Mifflin Co., among the United States’ oldest and largest education publishers.
The 174-year-old Boston-based textbook company will merge with the 11-year-old Dublin, Ireland-based software company under the name Houghton Mifflin Riverdeep Group PLC, when the deal becomes final by year’s end, a Houghton Mifflin spokesman said. The companies have combined annual revenues of $1.4 billion and earnings before taxes and interest of $392 million.
“We are excited about … the ability to capitalize on the convergence of print and digital platforms,” said Barry O’Callaghan, Riverdeep’s chief executive officer.
He is also the executive chairman of HM Rivergroup PLC, the new company formed to engineer the acquisition and merger. The company bought the traditional publishing concern from the private investment firms of Thomas H. Lee Partners, Bain Capital Partners, both based in Boston, and the New York City-based Blackstone Group.
The takeover of the venerable American firm, which has published such great American writers as Mark Twain and Henry David Thoreau, by a young, foreign, and smaller technology concern is a bold move, said industry analyst Trace Urdan, a managing director with Signal Hill, a San Francisco investment bank.
“This is like the minnow swallowing the whale,” he said.
It is also risky, Mr. Urdan added. The new company will shoulder $1.6 billion in net debt included in the $3.4 billion sale. Other companies have taken the same gamble and lost, he said.
Houghton Mifflin’s net sales in K-12 publishing fell 2.3 percent in the first nine months of 2006 compared with the same period in 2005, to about $780 million from $798 million. The company’s operating income for K-12 publishing rose 3.4 percent between those periods, from $186.8 million to $193.4 million, documents show.
Before the announcement, it was widely known in the industry that privately held Houghton Mifflin was planning to sell company shares to the public in the hope of raising $1 billion, which would reap benefits for its owners. The firms bought the company from the French media conglomerate Vivendi Universal SA in 2002 for $615 million in equity and $1 billion in assumed debt.
A Houghton Mifflin spokesman would not comment on the possibility of a potential initial public offering of company shares.
The convergence extends to the management of the new company. Houghton Mifflin’s president, chairman, and CEO, Tony Lucki, is a former member of the Riverdeep board of directors. Under the merger, the publishing concern will remain in Boston, and Mr. Lucki, will become the vice chairman of the new company.
Houghton Mifflin’s products include the Language of Literature anthology series for middle and high school students through its McDougal Littell division, which the company acquired in 1994, and the Iowa Tests of Basic Skills through its Riverside Publishing division. Riverdeep’s products include Reader Rabbit and Destination Success, its online math and reading series.
The sale of Houghton Mifflin is one more sign of the transition from print to Web-based curricula among publishers, experts say. Increasingly, publishers are embracing technology companies—and vice versa—to offer a blend of print and digital curricula that K-12 schools want, said Jay Diskey, the executive director of the school division of the Association of American Publishers, a Washington-based trade association.
Mergers-and-acquisitions activity in recent years in the education and reference market has been robust, with the London-based textbook publisher Pearson PLC leading the charge.
Earlier this year, for instance, Pearson won a $70 million contract in California to provide history curricula via digital books, videos, assessment, and interactive-learning tools to at least 1.5 million elementary school students. The company estimates that almost 50 percent of all K-5 students in the state will use those online products.
The Association of American Publishers rewrote its mission statement recently to omit “textbook.” Some of the group’s 300 members have never published traditional print books, such as digital publishers Learning.com, based in Portland, Ore., and Lakewood, N.J.-based Achieve3000.
Sales of digital instructional content by education publishers rose more than 52 percent in the United States from 2001 to 2005, from $152 million to $234.4 million, according to the AAP.
“Pearson Buys Top 2 Rivals in Student-Information Market,” June 7, 2006.
“Textbook Shortages Spur Digital Alternatives,” May 5, 2004.
“Vivendi Woes Roil Foreign-Dominated Textbook Sphere,” October 9, 2002.
“Houghton Mifflin Acquisition Extends Industry Trend,” June 13, 2001.
“British Publisher Set To Buy 2nd-Biggest Education House,” May 27, 1998.
Read a transcript of our exclusive online chat, Electronic Textbooks.
We’ve all slept through in-flight safety videos dozens (if not hundreds) of times. But most don’t have Elijah Wood, Peter Jackson, and other Hobbit cast members. Few feature the scenery of Middle-Earth, and effects that would make a micro-budget film weep. In fact, only one other video does: the last in-flight safety video from Air New Zealand. Now the company has a new video, dubbed “The Most Epic Safety Video Ever Made.” Watch this new Hobbit in-flight video below.
This is all, of course, because it’s time to promote a new Hobbit movie. The New Zealand tourism board loves the Middle-Earth movies, as they drive a great deal of money into the small and relatively isolated country. And so we see companies like Air New Zealand working with Jackson and his cast and crew to create specific promotions.
Tom Bosley, one of America’s most beloved actors, has passed away at age 83. Â Bosley was most famous for his portrayal as Howard Cunningham on Happy Days, but also did about a million other things, including the Father Dowling Mysteries and playing Sheriff Tupper on Murder, She Wrote.
The outpouring of love coming from Hollywood right now is tremendous, and it seems that everyone who ever worked with Bosley adored both him and his work. Â Bosley had been having a battle with lung cancer in a Palm Springs hospital when he died of heart failure yesterday morning. Â He was a beloved acting veteran and an all-around good guy, and he will be sorely missed.
Canada's best food bloggers dish on their greatest hits.
Photography “I use a Canon Rebel from a few years back, usually fitted one of the 50 mm lenses. When I take a photograph, I try to keep things simple; I’m hoping to convey a sense of sharing a meal with us, to capture the food within the context of the story.” M.L.
Photography I use a Nikon D-90, for my food I usually use an F1.8 15mm lens. N.A.
Home Jill Davies-Shaw (a.k.a. Sugar) blogs from her home in Edmonton, while Rhianna Morris (a.k.a. Cream) now blogs from New York City after recently making the move from Vancouver.
Day job Moving from pharmaceutical sales into the role of stay-at-home mom, Davies-Shaw continues to work with her husband and his Web design company White Spark. Morris works as a major gifts writer for Mount Sinai Hospital in New York City.
Photography Morris shoots with a Nikon D60 and Davies-Shaw shoots with Canon EOS Rebel XT. L.-E. A.
Idea From her home in Montreal’s Plateau, Parisian ex-pat Tanielian’s pretty recipes — stunning photography, with some illustration — are savoury, sweet and often travel-infused. The accompanying text has the intimacy of a diary dispatch from a cool friend, and a welcome self-deprecating tone. It’s en français but the combination of artful photos and Tanielian’s simple prose means a passing memory of high school Core French will suffice. The blog has yielded Tanielian not only foodie fans, but a collaboration with Fromages d’Ici, a promotional campaign for regional Quebec cheeses. Yes: a French woman endorsing non-French cheese! And that’s why we love Tanielian’s flabbergasting.
Photography A Reflex Canon EOS XSi. “It’s what I bought. Eventually I will change it but I find it’s not the camera that takes the photograph, but the eye behind the lens.” N.A.
Home Originally from Toronto, but moved to Vancouver about a year ago.
Photography I use a Nikon D90 with a 35 mm lens. I keep it simple as the food is eaten right after the picture is taken. I think it’s important to make the food look good. No one will want to make a dish if it doesn’t look appetizing. M.L.
Food for thought “Blogging is always a work in progress.” M.W.
Photography I use a second-hand Canon A520. It’s funny, at my going away party in Edmonton almost four years ago my friend gave it to me. I’m self-taught and just point and try to make it look nice. No other equipment. Sometimes I adjust the light by moving my curtains around. It’s low-tech around here!” N.A.
Day Job I teach seven- to 12-year-olds French at an independent all-boys school, Royal St. George’s College, in the Annex.
Food for thought “If your macarons aren’t turning out the way you’d like, consider the environment. The weather has a bearing on whether they’re going to work out or not. Humidity might not make them rise. If you don’t beat the batter enough you might not get the frilly edge.” M.W.
Photography “I started with a point and shoot back in 2009 and then I treated myself to a Nikon DSLR (Nikon 3100 and a 50 mm f/1.8 lens) about a year ago.” L.-E. A.
Favourite recipe “My favourite thing to make is a decorated apple pie, and I love making anything that requires chopping vegetables. It’s so therapeutic! Stews, casseroles and other classic comfort foods are always in my repertoire. But my absolute favourite Family Feedbag recipe is Sweet Chili BBQ Chicken. It’s pure saucy goodness!” R.T.
Favourite recipe “I love to bake bread. I have made all the bread for my family for the past five years or so. I bake sandwich bread weekly, but I also like to make bread with different seasonal items, such as fresh peaches, blueberries, cherries, corn or pumpkin. The Pumpkin Cranberry Yeast Bread on my site is probably my favourite. The dough is flavoured with pumpkin and studded with raisins, toasted pecans and fresh cranberries.” R.T.
Archives|O'CONNELL SCORED IN BASEBALL REPORT; Possible Indictment Depends on Conference Between Brothers and Judge Landis. FRISCH FULLY EXONERATED Assistant District Attorney Finds Nothing to Connect Him or Kelly and Young With the Case.
O'CONNELL SCORED IN BASEBALL REPORT; Possible Indictment Depends on Conference Between Brothers and Judge Landis. FRISCH FULLY EXONERATED Assistant District Attorney Finds Nothing to Connect Him or Kelly and Young With the Case.
Six adults were transported to hospital Saturday afternoon following a car crash along 16th Avenue near 68 Street N.E.
Thankfully, none of them were in life-threatening or critical condition, said EMS spokesman Adam Loria. Four people suffered minor injuries while the other two sustained serious soft-tissue injuries and possible broken bones.
Calgary Fire Department batallion chief Allan Ball said the collision appeared to be head-on between one vehicle carrying five people and another with a lone driver.Thankfully, none of them were in life-threatening or critical condition, said EMS spokesman Adam Loria. Four people suffered minor injuries while the other two sustained serious soft-tissue injuries and possible broken bones.
Calgary Fire Department batallion chief Allan Ball said the collision appeared to be head-on between one vehicle carrying five people and another with a lone driver.
Keep that lawyer's number handy.
Jim Jones better be sure his lawyer game is extra proper. The Harlem rapper was hit with 5 felonies tagged to the incident where cops claimed they chased a car in which he was a passenger.