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Using the medical text corpus, Watson then proposes medications–including drugs that made it through various stages of the FDA process but never arrived on the market—that could be used to potentially treat the patient’s cancer. Boards at the hospitals actually treating the patients finally take Watson’s recommendations under consideration and evaluate their feasibility for fighting the individual patient’s glioblastoma.
Watson is just one of many software platforms being used to tackle extremely thorny health issues through computational biology. One NYGC member institution, Mount Sinai’s Icahn School of Medicine, hired Cloudera cofounder and early Facebook data scientist Jeff Hammerbacher to oversee the hospital’s big data efforts. Using software from companies like pharma/sports/intelligence outfit Ayasdi, Mount Sinai runs extremely complicated algorithmic exercises on data sets like a patient’s diabetes history. In one project Fast Company‘s Co.Exist gained access to, biomedical informatics director Joel Dudley visualized the data of more than 300,000 patients to help pinpoint specific genes which might be influencing the course of one individual’s Type 2 diabetes.
Then there are the many smaller companies building servers and software platforms designed for pure science efforts that could someday lead to the creation of better drugs and treatments. One of them, Silicon Valley-based Bina Technologies, manufactures integrated software/hardware appliances designed for gene sequencing. CEO Narges Bani Asadi told Fast Company that platforms such as her company’s product drastically decrease the time it takes for researchers to decode cells; in one example, genetics researchers at Stanford University were able to shrink a 12-day genome decoding process into just two days. This does more than allow research to progress faster; it also saves organizations like Stanford and the NYGC money that can then be reinvested in more research.
Because computational biology is a relatively new field, it is wide open for both smaller and larger companies to turn themselves into market leaders. For larger companies like IBM that are widely believed to have declining market share and cash-flow problems, industries with well-funded customers like the National Institutes of Health, Stanford University, and the New York Genome Center are a godsend. Big Blue’s hope is that Watson–and products which leverage Watson–will become a commonplace part of the computational biology arsenal, and lock customers into IBM’s ecosystem with lucrative multi-year contracts. The company has already partnered with WellPoint to make a series of Watson-based tools.
Six students graduated from the Conemaugh Medical Technology Program. Front row, left to right: Laura Plitman, Jonathon Koshir and Alexandria Godissart. Back row, left to right: Brittany Hobbins, Ashley Swiderski and Jessica Ritzman.
Two upsets in a row?
How does a new driveway, home theater system, wood stove or sunroom sound?
Dream about it or make it a reality with a visit to the 17th annual Eastern Pennsylvania Spring Home Show this weekend at the Agri-Plex at the Allentown Fairgrounds. Home builders, landscapers, plumbers, roofers, bath and kitchen remodelers — representatives from nearly 200 companies — will be on hand to discuss their products and services.
Vendors range from services such as A+ Waterproofing & Foundation Repair of Bath, Creative Closets of Allentown and Hassler Roofing of North Whitehall Township to cable and utility companies such as RCN, PPL and Service Electric.
Don’t miss a hot tub blowout sale presented by Daniel’s Lawn & Garden Center of Harleysville, Montgomery County, and a large-scale model railroad exhibit presented by Lehigh Valley Garden Railroaders.
You also can enter to win an American Heritage Tacoma Pool Table from Allentown Tables, an 8-foot by 10-foot mini barn from RG Services and a shed from All Amish Structures of Orefield.
Hours are 5-9 p.m. Friday; 10 a.m.-6 p.m. Saturday; 10 a.m.-5 p.m. Sunday. Tickets are $10; $8, seniors; free, children under 12; get $1 off by bringing a non-perishable food item to benefit local food banks. Agri-Plex is at 302 N. 17th St. Info: 860-918-0891; jenksproductions.com.
A meteor shower will be shooting across Bay Area skies early Sunday morning, although cloudy, rainy weather may diminish chances of a clear viewing, a local astronomer said.
Weather permitting, Chabot Space and Science Center astronomer Ben Burress said the best time to see the Leonid meteor shower will be Sunday morning around 2 a.m. and 3 a.m.
Burress advised getting away from city lights and facing east to see the shower, which will have about 10 to 15 meteors shooting an hour.
"For meteor showers we encourage people to find a darker place," he said.
After near record setting heat this Week the weather pattern has taken another extreme turn with 2 storms in 48 hours. Details on both systems & what this means for your Weekend in Chief Meteorologist Jeff Ranieri's forecast.
Leonids has a strong showing every 33 years, the astronomer said, with this year not expected to be as remarkable as past years.
"It's on the quieter side as far as showers go," Burress said.
The shower is named after the constellation it appears to coming from -- in this case, Leo, which depicts a lion.
The Leonids are associated with the comet Tempel-Tuttle, which was discovered in the 1860s.
Meteor showers happen when Earth travels through a trail of dust left behind by a comet, Burress explained.
A good news story that like all other good news stories gets ignored by the usual suspects.
Quote bookmarked for future use. I'll be sure to watch for your praise of good news articles once a party not of your liking is in power.
LordEd wrote: Quote bookmarked for future use. I'll be sure to watch for your praise of good news articles once a party not of your liking is in power.
Everyone who has a case against Cactusflower rests their case.
Didn’t know there was a contest....... not everyone has time to scour the internet just to post articles on a forum.
If this was a court of law, the "case" would be dependent upon the party being able to prove that they are capable of rational thought processes.
I have not seen anything that comes remotely close to that prerogative.
Please do this before you hurt someone or yourself. The community has resource for people in your position.
Just ask and we will work to get you the help you need.
what a bunch of bullies.
Because_They_Lie wrote: what a bunch of bullies.
There's a reason it's called the bickering room.
You are free to walk away at any time.
I didn't realize it was the bickering room, they do it in all rooms.
thanks for the permission weirdo.
Because_They_Lie wrote: I didn't realize it was the bickering room, they do it in all rooms.
Not that it's right, but some people are just begging for the ridicule.
Women veterans are encouraged to attend a Veterans Affairs town hall meeting next month in Fayetteville.
The town hall will be from 4 to 5 p.m. April 2 at the Fayetteville VA Health Care Center, 7300 S. Raeford Road.
It coincides with the Advisory Committee on Women Veterans conducting site visits in North Carolina on April 1-5, officials said.
The committee advises the secretary of veterans affairs about women veterans’ needs related to health care, rehabilitation, compensation, outreach and other programs and activities administered by the VA.
Officials said the town hall is open to the public, especially women veterans and stakeholders.
Veterans, staff and stakeholders will be able to ask questions and provide comments to the Advisory Committee on Women Veterans.
Veterans Benefits and National Cemetery Administration representatives are also expected to attend.
Attendees also can learn about VA women’s programs and services.
The committee will meet from 9 a.m. to 2 p.m. to discuss facilities, programs, demographics and other services.
Public comment is welcomed during the town hall, or written statements for the committee's review may be submitted to 00W@mail.va.gov, or by fax at 202-273-7092.
Because the system lacks an organized core, it’s difficult to forecast a storm track, said AccuWeather senior meteorologist Dan Kottlowski, but models so far show it nearing land near the Florida Panhandle or Louisiana coast.
Read more: So it’s going to rain all Memorial Day Weekend – here’s why we’re super happy about that.
Flooding is possible because the area has already received so much rain, he said.
The slow-moving low pressure system began drawing meteorologists attention last week when computer models began to suggest possible development, Kottlowski said. While the official hurricane season doesn’t start until next Friday, Gulf waters are already warm enough to fuel a tropical cyclone if atmospheric conditions are favorable.
The system’s proximity to the Belize coast and wind shear have so far kept it in check. But by Friday or Saturday, upper level winds are expected to move east, forcing the low pressure system to the north.
“As the low pressure moves away from land, then it will have nothing but the open part of the Gulf to move over,” Kottlowski said.
If a subtropical system forms, stronger winds will occur around the storm’s edges rather than the center. Subtropical systems are similar to tropical systems and produce the same hazards — wind and heavy rain — but don’t have the warm center, he said.
Heavy rain appears to be the system’s biggest threat to land and a concern for South Florida, which has been hammered by rain over the last month. In some places, rainfall is more than three times the monthly average, a dramatic leap from April when totals fell well below average, left the region abnormally dry and fueled wildfires across the Big Cypress National Preserve.
The Gulf Coast should also lookout for heavy rip currents, forecasters said.
The fallout from the DDoS attack that hit Twitter, Facebook, YouTube and other Web 2.0 sites continued even after the attack had officially ended. Hacktivism or not, Web admins need to take precautions to protect against DDoS attacks.
The fallout from the distributed denial-of-service attack that hit several Web 2.0 sites Aug. 6 has taken a couple of twists and turns.
Besides knocking out Twitter for a time on the Aug. 6, the attack triggered a response from the company that a day later disrupted service for some users. According to Twitter, its defensive measures blocked some Twitter clients from communicating with Twitter's API, leaving them unable to tweet via SMS.
If that wasn't enough, researchers at McAfee found attackers have begun leveraging interest in the situation to spread malware by using search engine optimization techniques to lure users into clicking on search results leading to malicious sites.
All this because of an apparent act hacktivism targeting a pro-Georgian blogger named "Cyxymu."
"It's not surprising that political motivation is mentioned where major DDoS attacks are concerned, as many services now play key roles in politically charged events," said Chris Boyd, director of research at FaceTime Security Labs. "However, it's important not to get carried away with 'the Reds under the bed' way of thinking-recent attacks on key U.S. Websites were blamed on everyone from China to North Korea, with no smoking bullet evidence that these attacks were ever officially sanctioned."
What is known is that the attack hit Facebook, Twitter, YouTube, Fotki and LiveJournal. Researchers are still on the trail of whoever was behind it, but have determined the attack packets sent to the Websites were requests to fetch pages hosted for the blogger, who reportedly had just recently blogged about the upcoming anniversary of the war between Russia and Georgia.
Between this incident and the recent DDoS attacks targeting both public and commercial Websites in the United States and South Korea, Web administrators are advised to take precautions to secure their own sites, said John Harrison, group product manager at Symantec Security Response. For starters, admins should have spare IP addresses registered as well as the ability to swap them in for attacked IPs via DNS. They should also familiarize themselves with the capabilities of their ISP and have a monitoring system to provide an early warning.
"When under attack, there are a variety of mitigation techniques; most are specific to the type of DDoS attack," he said. "Use technologies, including firewalls and routers, to block or redirect IP addresses and types of traffic. Involve others, the ISP and perhaps the ISPs of attacking clients. Web admins can add the additional IP addresses they have in reserve and move services off the attacked servers."
There isn't too much end users can do, but they should steer clear of any sites affected by a DDoS while it's going on.
"Computer users are also encouraged not to visit sites that are rumored to be under a DDoS attack for the sole purpose of seeing what happens," he said. "This -rubbernecking' type of activity, similar to that which happens when there is an accident on the freeway, only causes an increase in traffic to the site, which will only delay access to the Website even longer and prolong the attack."
Pushing up the price: Govt toying with45p minimum per unit of alcohol.
The government has taken further action on problem drinking, by once again announcing the same consultation it had originally planned to hold during the summer.
The delay could be a result of behind-the-scenes disagreement on the minimum pricing strategy. Former health secretary Andrew Lansley was uncomfortable about the plan but his replacement, Jeremy Hunt, is more comfortable with it.
"It's classic smoke and mirrors from the Home Office," shadow crime and security minister Diana Johnson said.
"The debate about levels needs to be based on evidence of what will work. But the government needs to make sure it does not just create a cash windfall for the supermarkets, instead of lowering prices of other goods or supporting better prevention and treatment of alcohol abuse to cut crime further and save lives."
The ten-week consultation will assess whether a minimum 45p per unit price for alcohol would reduce problem drinking and help clean up disorder on British high streets on weekend evenings.
It will cause irritation in the drinks industry but is more moderate than the 50p level planned in Scotland.
The consultation may also look into cracking down on multi-buy promotions.
A health committee report last week said the government was overly concerned with reducing disorder to the detriment of tackling the health problems of binge drinking.
About 12 years ago, in a previous incarnation as a sports writer, I went to Spain to interview Seve Ballesteros.
He was well past his pomp as a tournament golfer, but still radiated such electric charisma that an afternoon in his presence felt like being wired to a generator.
I confess, then, to rather apprehensively taking my seat for this biographical blend of documentary and drama.
The project was conceived by producer Stephen Evans, who was inspired by Senna, the story of the great racing driver. But motor-racing is almost by definition more cinematic than golf.
It’s no accident that the most successful golf films are knockabout comedies, Caddyshack and Happy Gilmore, or that the previous best golfing biopic, Follow The Sun (about Ben Hogan), dates from 1951.
So, could this possibly do justice to the stirring tale of the youngest of four sons of a humble farmer, who honed his remarkable talent by hitting pebbles with a makeshift club on the beach near Santander? It does. Like its subject, Seve the film has irresistible charm, and becomes genuinely moving as it chronicles the health problems which killed him in 2011 at the age of 54.
Of course, the archive material was always going to be powerful; he was the most watchable golfer not only of his own era — but arguably of any era. But what about the dramatisation of his early teens, when his prodigious gifts became apparent?
Happily, that works, too. Jose Luis Gutierrez was picked to play the young Seve mainly for his golfing skill and at times his acting, not inappropriately, is slightly below par. Moreover, the story of his family, dirt-poor but happy, is romanticised to within a tee peg of its life.
Yet none of that really matters. Director John-Paul Davidson deftly combines the engaging drama with the archive footage. Whether the result will appeal to non-golfers, I’m not sure.
Paper designer Benja Harney recently created a number of papercraft designs for multi-brand store Incu's Window Project.
Paper designer Benja Harney recently created a number of papercraft designs for multi-brand store Incu’s Window Project. The Sydney-based artist created a number of works under the theme ‘all things British’ to celebrate the recent arrival of Topshop to Aussie shores. Overall the project aims to celebrate the work of “local and international artists through a platform of changing installations at our retail stores.” Avant-garde fashion label Romance Was Born will also participate in the project.
Kylie Minogue and Peter Andre talk the success of the Butterfly Ball | HELLO!
May 19, 2014 - 16:37 BST hellomagazine.com Kylie Minogue and Peter Andre talk about the work achieved from the annual Butterfly Ball.
Kylie Minogue and Peter Andre were among a stellar list of celebrities who turned out to give their support at the annual Butterfly Ball, and HELLO! can reveal they also met up with some of the children and families earlier in the day at an exclusive meet-and-greet.
"The work that John and everyone at Caudwell Children do is so inspiring," said Kylie as she met up with some of those who have benefited from the charity, ahead of the evening celebrations last Thursday at London's Grosvenor House Hotel.
The charity's ambassador Peter Andre added, "The glitz and glamour of the evening is fantastic. But you only have to scratch beneath the surface to see the truly incredible work Caudwell Children too."
The evening, which raised £2.5million for the charity founded by John Caudwell to help youngsters and their families in the UK, was also attended by Sarah, Duchess of York, Simon Cowell, Tamara and Petra Ecclestone, Holly and Nicky Candy, David Furnish, Petra Nemcova and Sinitta.
Trudi Beswick, Chief Executive of Caudwell Children told HELLO!: “It has been an overwhelming success, everyone has had a fantastic night and we raised a record amount. I can’t thank everyone enough for their support in making the event such a success.
WASHINGTON — House Republicans from the Freedom Caucus held a small meeting on Capitol Hill to Tuesday delve into the ongoing investigation of former House IT staffers who performed work for Democratic members.
Republican Texas Rep. Louie Gohmert, Republican Ohio Rep. Jim Jordan, Republican Iowa Rep. Steve King, Florida Republican Rep. Ron DeSantis, and Republican Pennsylvania Rep. Scott Perry all gathered at a Rayburn Office Building room to talk to three witnesses about the case.
Imran Awan and his colleagues — Hina Alvi, Abid Awan, Jamal Awan, Rao Abbas, and Natalia Sova — worked for these members for over 10 years. During this period, they allegedly performed a voucher fraud operation, ghost employee scam, stealing equipment, and breaching security protocols in the capitol by making large data transfers to an offsite server.
Capitol Hill Police first launched an investigation into Awan and his associates at the beginning of the year and every member who employed them dropped each from their payroll — except for Florida Democratic Rep. Debbie Wasserman Schultz.