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At the same time, the emergence of Blue Note/ArtistShare will allow fans to be involved in the creative process of discovering new talent and in funding the music -- which makes the partnership something of a low-investment for Blue Note.
“Young artists worldwide are making fresh musical statements left and right, but are forced to do their own marketing campaigns, too, often when their main focus should be their creative output,” said Lundvall in a statement. "I see the ArtistShare business model as a key component of the future music business."
Endeavors such as Blue Note/ArtistShare show both the potential for finding new talent through crowdfunding and how the platform is increasingly becoming a strategy for larger companies. In recent years the market for music crowdfunding platforms has grown exponentialy. In addition to Kickstarter and ArtistShare, other...
In 2011 Universal Music Group, Blue Note's parent company, and Talenthouse launched a deal to conduct fan-engagement contests as a form of crowdsourcing. The contests allowed fans to collaborate on various art designs such as t-shirts and cover art images for their favorite artists.
According to a recent report by Croudsourcing.org, crowdfunding of global projects in 2013 will increase $2.4 billion in 2013 to $5.1 billion -- nearly doubling the $2.7 billion raised in 2012.
Successful ArtistShare musicians include composer Maria Schneider, jazz guitarist Jim Hall, The Clayton Brothers, pianist Danilo Perez and saxophonist Chris Potter. According to ArtistShare, their crowdfunded projects include 6 Grammy Awards and 18 Grammy nominations.
The most famous example of a musician's crowdfunding success is Amanda Palmer, who last year raised $1.2 million dollars via Kickstarter to fund her album, companion book, and tour. The album sold nearly 85,000 albums globally in six months.
In addition to its famed catalog, which features the music of such jazz luminaries like Miles Davis, Thelonious Monk, and John Coltrane, Blue Note Records has been active in the technology space, most recently with its acclaimed Spotify app launched last September.
Bryce Olson looked up his prognosis on Google. He had, give or take, 21 months to live. A year earlier, in 2014, he was diagnosed with metastatic prostate cancer at the age of 44. Olson underwent standard therapy: removal of the prostate gland, followed by six rounds of chemotherapy that left him with mouth sores and n...
Fast forward to 2018, and Olson is alive. Ignoring his prognosis, he orchestrated his own treatment by assembling a team of scientists, requesting to have his genome sequenced and seeking out targeted therapies. His job as global head of marketing for health and life sciences at Intel gives him a mighty platform to adv...
Researchers at UC San Diego Moores Cancer Center and the Translational Genomics Research Institute have been eager to help, by donating time and effort. “To do genomics we need people to work with us, not a bunch of mice,” says Ida Deichaite, director of industry relations at UCSD Moores Cancer Center.
Genomic sequencing tests that identify genetic alterations can cost thousands of dollars. Insurers are slowly beginning to cover them. Last month, Medicare announced it will pay for sequencing tests, such as Foundation Medicine’s FDA-approved FoundationOne CDx, which has a list price of $5,800. Coverage is only for pat...
Only three years ago, precision medicine was more promise than reality. When Olson joined Intel’s life sciences group in December 2014 in Portland, he found out that his colleagues were working with cancer pathologists at Oregon Health & Science University (OHSU) to sequence tumors and analyze cancer patient data. Yet,...
He learned that mutations in a couple of genes, Pi3K and PTEN, were allowing cells to proliferate uncontrollably. Cedars-Sinai Medical Center in Los Angeles was conducting a phase 1 clinical trial for an oral Pi3K inhibitor developed by Verastem. Olson called up the investigator asking to enroll. The response: “Sorry, ...
The vast majority of Phase 1 clinical trials, which monitor the safety of drugs, fail and this one folded because of cardiac side effects. It worked for Olson. His prostate specific antigen (PSA), a protein made by the prostate that can indicate cancer, went down to zero and he was left with only a small pelvic bone le...
Not entirely surprising. A study published in JAMA Oncology in 2016 showed that patients who were in phase 1 clinical trials based on their genetic markers responded better to treatment than those selected randomly.
Right before his supply of Pi3K inhibitor ran out in April 2017, Olson got a bump in his PSA. He enrolled in another Phase 1 trial at the University of Oklahoma Stephenson Cancer Center, but a similar Eli Lilly Pi3K inhibitor failed to stop the rise in PSA. Olson opted out after two months. He now needed to find out wh...
In September 2017, he got an unexpected visit from Deichaite, who helps faculty members at UCSD Moores Cancer Center turn lab work into potential treatments. Gilles Frydman, a well-known supporter of cancer patient advocacy, put her in touch with Olson. “I suggested we become partners in research,” says Deichaite.
Olson’s fifth vertebra—near the top part of his spinal column—showed lesions. Christina Jamieson, who researches bone metastatic prostate cancer at UCSD, scraped DNA from a fragment of his T5 vertebra. Using a sample, she developed 3-D cell cultures called organoids that mimicked the metastasis, and grafted them into t...
Olson also underwent one round of radiation, followed by three months on Provenge, a drug that harnesses the immune system to fight advanced prostate cancer.
He and Ludmil Alexandrov, a computational biologist at UCSD and an expert on mutations, discovered that 60% of Olson’s mutations were associated with a deficiency that prevents damaged DNA from repairing itself—similar in signature to alterations in the BRCA gene, which increases the risk of breast and ovarian cancer. ...
Comparing Olson’s information with data from Stand Up to Cancer on patients with metastatic prostate cancer, Tamayo also pinpointed other genes, which could play a role in bone metastatic prostate cancer, and mapped out tumors that resembled Olson’s.
Earlier this week, Olson found out that his PSA level was up. He knows he has options—tailored to him. He could be a candidate for PARP inhibitors, which can stop cells from proliferating. (The FDA has approved this class of drugs to treat advanced BRCA-mutated ovarian and breast cancer.) He could also dig deeper into ...
“I’ve got data on my side,” says Olson.
Did medics do enough to save dying Austin-area man?
Emergency officials are investigating whether paramedics who responded to a hit-and-run last fall did enough to help a dying man, raising the question of how far first responders should go to save a gravely injured patient.
The issue arose after body camera video captured a roadside dispute between medics from Austin-Travis County Emergency Medical Services and Travis County Fire Rescue, who pressed for permission to keep working on 73-year-old Joe McKoy after they discovered he was still breathing after the Sept. 27 crash.
McKoy, who suffered a severe head injury, was not taken to the hospital. He was pronounced dead at the scene near Texas 130 and Pearce Lane about 30 minutes after the crash. Records show medics called a doctor for consultation and, later, to declare him dead.
The case highlights how medics must sometimes grapple with the extent to which they should continue care when training and experience indicate that survival chances are low or whether they should be empowered to deem a patient no longer viable for treatment, as officials say medics did with McKoy, and stop.
Dr. Mark Escott, medical director for Austin-Travis County Emergency Medical Services, confirmed he and his office have been investigating whether first responders followed the agency’s standards for care. He said he could not comment further because such clinical reviews are confidential under state law. He said the m...
The medics have not been disciplined and remain on the job. The Texas Department of Public Safety is still investigating the crash and trying to find the driver of the other car.
McKoy’s husband, Jesse Stewart, was dead when paramedics arrived at their mangled pickup.
Body camera video taken by first responders from Travis County Fire Rescue Emergency Services District 11 captured tense moments with medics from Austin-Travis County EMS during which they discussed McCoy’s injuries and debated whether to proceed with treatment.
It shows some responders on the scene appeared stunned when a medic — the one with the most credentials at the scene — instructed them to cease efforts to aid McCoy because of the dire nature of his injuries.
The Statesman, KVUE-TV and McKoy’s family have sought copies of the video from Travis County Fire Rescue, but the agency's attorney has appealed to the Texas attorney general, seeking to prevent the public release of the video. The department argues that because the body-worn cameras are used for medical review purpose...
McKoy’s brother, Errol McKoy, who is handling his estate, declined to comment.
Documents list all the emergency responders at the scene, but officials would not identify who objected to further treatment of McKoy, a retired Internal Revenue Service examinerwho lived in southeastern Travis County. The men's neighbors think they had been grocery shopping when the crash happened.
The video shows the senior EMS medic believed the nature of McKoy’s injuries were such that they met that criteria because of his head wound. Records also show he was bleeding from his head and suffered severe brain trauma.
The policy also establishes an on-scene hierarchy and instructs medics on how to handle instances where they disagree about patient treatment.
It says it is the responsibility of the “on-scene credentialed providers to reach consensus as to the most appropriate care of the patient.” It says if that doesn’t happen, the senior on-scene provider has the final say.
“All significant or unresolved conflicts regarding on-scene management of patients should be reported via the chain of command and will be retrospectively reviewed,” the policy states.
In a memo to staffers Friday, Bailey, the Travis County Fire Rescue chief, said the final call about whether to take a person to the hospital remains with the transport provider, which was Austin-Travis County EMS in McKoy's death. However, Bailey pointed out that his department has other options, including arranging o...
"While the expectation is to be professional in our communication with others, this should not be a passive effort, but rather a clear communication of your concern," Bailey wrote.
Dr. Pat Crocker, a former emergency room doctor in Austin who worked closely with EMS, said medics often contacted him for counsel about how to proceed with a patient in similar situations.
Dr. James Kempema, the medical director for Travis County Fire Rescue who also reviewed the incident, said he agrees that McKoy would not have survived his injuries even if the medics had continued aggressive treatment.
However, he said the incident shows the difficult decisions medics must make in an emergency situation about whether to rush a person with the most dire injuries to the hospital. Doing so can put the crew and public at risk by an ambulance racing to a hospital. It also comes with an extra financial cost to the agency, ...
However, he said taking such patients to the hospital can give a possible opportunity for organ donations and allow doctors and other medical experts a second chance to review a patient’s injuries.
Kempema said he is aware of instances in which paramedics brought patients with injuries similar to McKoy, even though they were nearly certain the patient would die en route. He said he thinks it is usually proper to do so.
“Trying to determine when to stop resuscitation efforts is a challenge,” Kempema said. “My recommendation is that if there is evidence of vital signs and we have a trauma center that is fairly immediately accessible, my general recommendation would be to pursue transport. There are some things we might be able to do, w...
Bailey said his medics also have reviewed their actions that day. He said they also have repeatedly second-guessed whether to stop care on McKoy and whether they should have more aggressively insisted on doing more.
No country can become stronger by encouraging confrontation, says Rajnath Singh.
A day after Income Tax raids were conducted at premises linked to the relatives and aides of Madhya Pradesh CM Kamal Nath, Home Minister Rajnath Singh on Tuesday rejected the Congress party’s accusation of political vendetta, saying the government has nothing to do with it. Speaking to ANI, Rajnath said it will be unfa...
“Government should not be blamed. It will not be fair to the government. This is a continuous process. Maybe agencies have some information. But it will be wrong to say these raids were conducted under instructions,” he said while speaking to ANI in an interview where he touched upon various issues ahead of the Lok Sab...
On Monday, the I-T Department claimed it detected a racket of collection of unaccounted cash of bearly Rs 281 crore during raids against close aides of Madhya Pradesh CM Kamal Nath and others. The department also claimed that sleuths recovered Rs 14.6 crore of “unaccounted” cash and also seized computer files and diari...
Last year Delhi CM had also blamed the BJP-led governmnt at the I-T department’s raids in 16 premises linked to a tax evation case aganst minister Kailash Gehlot in Delhi and NCR.
Slamming Congress president Rahul Gandhi over his criticism of the BJP’s manifesto being a one-man job, the Home minister said, “In India’s political history, never has it happened that so many people were involved for preparing one manifesto. Whatever he said is baseless. He keeps on saying such things”.
Speaking on the issue of lynching and attacks on Kashmiri students in several parts of the country, Rajnath Singh added that those found guilty will be dealt with severely. “As Home minister, I assure that those who do anything wrong will be strictly dealt with. I have said this earlier that wherever Kashmiri students ...
Rejecting reports of a shortage of jobs in the country, he pointed out that jobs have increased in the country. “Nobody can promise any number of jobs. With the economy booming, and development of infrastructure and manufacturing sector also doing well, job creation in the country will increase,” he added.
Long-distance commutes are often a nightmare and an uncomfortable experience. I have had the misfortune of travelling to Limpopo in the most cramped, uncomfortable taxis with such bad ride quality, it felt like the seats were scraping the tar road.
Standing in the queue and seeing a Mercedes-Benz Sprinter pull in always had me celebrating because it meant better seating, more space, a better ride and a more pleasant commute than one would have in a smaller taxi.
This sense of safety and comfort is what this bus offers in the transport sector and it just got a whole lot better. Mercedes-Benz has launched the third-generation Sprinter and it has improved on all fronts, especially the safety features, which I will touch on in a moment.
Styling-wise, the Sprinter has been refreshed and modernised and some nips and tucks have made it much sleeker and more appealing. Looks, however, are not that important in this sector as comfort, functionality and safety are key qualities in a mass people-carrier.
So how functional is the Sprinter? Well, firstly, it offers customers in a diverse range of industries more versatility and customisable applications than ever before. In total, there are 600 options available to customise the Sprinter for your needs.
The taxi industry for long-distance commutes is a big market for the Sprinter, and globally SA has the biggest market share with the Sprinter Inkanyezi. Commuters can now enjoy added comfort with USB charging ports under all the rear seats, added shoulder and leg room, electric sliding door (high-end model) and free-fl...
This latter function can easily be taken for granted, but for those who often use taxis, we know how stuffy it can get, especially when those sitting near windows seem averse to fresh air! However, I am certainly more impressed by the individual USB charging ports. That is some business-class stuff right there!
The launch was held at the Kyalami racetrack, where the aim was to have the motoring media experience safety features first-hand.
I will admit I was a little intimidated by the thought of hauling this van on the track, well, anywhere for that matter. But, as with a lot of big vehicles these days, their enormity is balanced by their car-like feel. A few courses were set up on the track, where we could get behind the wheel and feel the updated safe...
The safety-assistance features are really impressive. The active-brake assist was a highlight where safety features are concerned. The van is able to instantly alert the driver to oncoming danger when doing a sudden turn at full acceleration, to avoid a collision. Depending on the size and obstacle ahead, it will send ...
This, along with lane keeping assist, reverse camera, active distance assist distronic —which automatically regulates the distance from the vehicle ahead and decreases speed if the vehicle suddenly stops or decreases speed. These are all optional extras, with the standard features being cross wind assist, which makes t...
In such a big van that hauls 22 passengers, one would like to see more than just front collision airbags installed. The interior focal point is the revised dash layout and design that comes fitted with intuitive 7-inch screen or a 10.25-inch display screen with HD resolution that can also be controlled using the touch-...
The M-Bux Mercedes-Benz user experience “Hey Mercedes” is also an available option. What fun it would be to see this feature being used in a taxi. Though we were not exposed to too much driving on the public road, it handled well on fast cornering and feedback from the engine was quick and responsive in both manual and...
There are derivatives: a 2,2 litre four-cylinder diesel engine with an output of 84kW/120Nm, a new 120kW/380Nm variant as well as a 140kW/440Nm option that gives a punchier response. Drivers with a code 8/code B licence will be happy to know they can legally drive the new 3.49 ton variant GVM Sprinter. This was previou...
This commercial van offers a number of variants for countless industries. With more customisable options than ever before, the Sprinter makes the ideal van for a more personalised package. Whether it be in hospitality as a shuttle, ambulance services, delivery van or even a mobile food truck, the options are limitless.
Prices start at R461,783 and go up to R815,925. For a taxi, add an extra R200,000 to the base price.
Around 60,000 vehicles of the Mercedes-Benz GLK 220 CDI models produced between 2012 and 2015 were reportedly affected.
225kW four-door coupé will make its world premiere at the New York International Auto Show next week.
Sure the holidays are kicking off in the United States officially tomorrow, but that doesn't mean it's all cheer and sunshine (certainly not on the East Coast).
How storage vendor EMC is building a business focused around software as margins on storage hardware decline.
It's business and fighting words as usual in the brewing legal war between EMC and Pure Storage, and there is certainly no love lost in this debacle.
Following EMC's launch of a suit earlier this month , Pure Storage has retaliated in what it dubbed as "Round 2."
Pure Storage CEO Scott Dietzen kept up his company's defense in a blog post on Tuesday, reiterating that Pure Storage has never intended to "impede EMC’s go-to-market efforts," but rather just promote "ongoing competition."
EMC had accused the flash array maker of stealing trade secrets by concocting a "deliberate scheme" in "collusion with numerous former EMC employees" in obtaining trade secrets and other sensitive information belonging to EMC.
In its preliminary filing submitted at the U.S. District Court in the District Court of Massachusetts on November 4, EMC named all of its former employees that have jumped ship to Pure Storage in relation to this case.
The IT giant's suit against Pure Storage as a company follows up smaller legal cases filed against at least six former EMC/now Pure Storage employees over the last six months.
This week, the Hopkinton, Mass.-based corporation kept the ball rolling by throwing patents into the mix, charging that Pure Storage has violated at least five patents related to data storage that flowed in thanks to the 2012 acquisition of XtremIO.
On a related note , EMC made its big move into flash arrays in mid-November with the general release of its upgraded and fine-tuned XtremIO, touted for its deduplication, data protection and raw speed and efficiency improvements.
We are now in the process of reviewing the EMC patent claims, but as the first mover in all-flash arrays, we are very confident in the strength of our own IP portfolio. Moreover, Pure Storage is sufficiently well capitalized (and we have our entire $150m recent round in the bank) to successfully defend ourselves, as we...
Bus Éireann is progressing through a transformation plan as the competitiveness of the transport industry becomes ever more a reality, with a clear need to establish the business on a strong commercial footing. Establishing an accelerated digital strategy and capability is a key dependency for Bus Éireann’s success.
Bus Éireann is now seeking to appoint a Chief Information Officer based in Dublin and reporting to the Chief Executive. This is a new position.
The Chief Information Officer will have responsibility for Bus Éireann’s enterprise wide digital vision and strategy. He/she will lead the development by translating the business strategy into a clear technology roadmap guiding the business on technology architecture and infrastructure choices. The appointee will have ...
The role of Chief Information officer requires a minimum of 15 years professional experience in increasingly executive level roles in a large corporation/s. Familiarity with transport technology is highly desirable. The ability to build a successful technology vision and roadmap is essential along with the building of ...
The BS/MBA program reduces by one year the usual pattern of a conventional four-year BS in business administration program and a two-year MBA program. Students accepted into this program must meet undergraduate requirements exactly as specified in the following course schedule for the first three years. Any deviation i...
Outside air blows hot, cold and dusty, but it cools just as well in datacenters as expensive air conditioning, according to Intel.
Fresh air could save millions in datacenter cooling costs, Intel has claimed, after a successful experiment in the New Mexico desert.
Replacing air conditioning by piping in outside air saved power costs with no appreciable increase in server failure rates, the company concluded in a research paper. Despite a lot of dust and major temperature changes--both long considered undesirable in datacenters--the equipment wasn't affected, said Intel.
"Servers... were subjected to considerable variation in temperature and humidity, as well as poor air quality; however, there was no significant increase in server failures," said the paper. "If subsequent investigation confirms these promising results, we anticipate using this approach in future, high-density datacent...
Intel estimated an annual cost reduction of approximately $143,000 (£79,000) for a small, 500kW datacenter, based on electricity costs of eight cents per kWh. In a larger 10MW datacenter, the estimated annual cost reduction was $2.87 million.
Intel used a normal air filter that took larger particles out of the air but not fine dust. While the 32 servers and racks became coated in dust, and humidity was monitored but not controlled, the failure rate was 4.46 percent, compared with a 3.83 percent failure rate in Intel's main datacenter over the same period.
The experiment was run for 10 months, between October 2007 and August 2008. Server units with over 900 blades, used for production design, were split into two compartments. One of the compartments was air cooled, with temperatures ranging from 18 to 32°C. The other compartment was cooled using air conditioning, and use...
Intel set up the experiment to challenge assumptions about optimal operating conditions in datacenters. Received wisdom has it that temperature, humidity and air quality must be strictly maintained.

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