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Donald Glover/Childish Gambino in the music video for "This is America."
Bruno Mars ft. Cardi B — "Finesse (Remix)"
Camila Cabello ft. Young Thug — "Havana"
Childish Gambino — "This Is America"
Cardi B performs onstage at the 2018 Billboard Latin Music Awards.
Dua Lipa's "New Rules" video.
Dua Lipa — "New Rules"
Post Malone ft. 21 Savage — "rockstar"
Cardi B performing at Coachella in 2018.
The video for N.E.R.D and Rihanna's "Lemon."
Bebe Rexha ft. Florida Georgia Line — "Meant to Be"
Jennifer Lopez ft. DJ Khaled and Cardi B — "Dinero"
Logic ft. Alessia Cara and Khalid — "1-800-273-8255"
N.E.R.D and Rihanna — "Lemon"
SZA performs at 2018 BET Experience Staples Center Concert in 2018.
Camila Cabello in the "Havana" video.
P!nk — "What About Us"
Shawn Mendes — "In My Blood"
Drake in the "God's Plan" video.
Cardi B ft. 21 Savage — "Bartier Cardi"
Migos ft. Drake — "o;Walk It Talk It"
Shakira and Maluma in the "Chantaje" video.
J Balvin, Willy William — "Mi Gente"
Luis Fonsi, Demi Lovato — "Échame La Culpa"
Maluma — "Felices los 4"
Shakira ft. Maluma — "Chantaje"
Dua Lipa in the "One Kiss" video.
Avicii ft. Rita Ora — "Lonely Together"
Calvin Harris and Dua Lipa — "One Kiss"
The Chainsmokers — "Everybody Hates Me"
David Guetta and Sia — "Flames"
Marshmello ft. Khalid — "Silence"
Zedd and Liam Payne — "Get Low (Street Video)"
Panic! At The Disco's "Say Amen (Saturday Night)" music video.
Fall Out Boy — "Champion"
Foo Fighters — "The Sky Is A Neighborhood"
Imagine Dragons — "Whatever It Takes"
Linkin Park — "One More Light"
Panic! At The Disco — "Say Amen (Saturday Night)"
Thirty Seconds to Mars —"Walk On Water"
Childish Gambino in the "This Is America" video.
Dej Loaf and Leon Bridges — "Liberated"
Beyoncé and Jay Z in "Apes--t."
Alessia Cara — "Growing Pains"
Eminem ft. Ed Sheeran — "River"
Justin Timberlake and Chris Stapleton in the “Say Something” video.
Justin Timberlake ft. Chris Stapleton —" Say Something"
Janelle Monae in the "Make Me Feel" video.
Janelle Monáe — "Make Me Feel"
Taylor Swift — "Look What You Made Me Do"
Ariana Grande —"No Tears Left to Cry"
Eminem ft. Beyoncé — "Walk On Water"
Kendrick Lamar and SZA — "All The Stars"
Jay Z and Beyoncé in the "Apes--t" video.
Bruno Mars and Cardi B –in the “Finesse (Remix)” video.
When I heard President Bush on Thursday morning call for "zero tolerance of people breaking the law during an emergency such as this," it gave me shivers.
I know he wanted to send a tough message to thugs stealing guns, drugs and flat-panel televisions, holding up hospitals, shooting at helicopters.
But doesn't he realize he would be heard by the moral equivalent of school administrators?
These are people who suspend girls for bringing Midol in their purses or butter knives in their lunchboxes.
What would they do to a kid who steals a bus?
When he arrived at the Astrodome about 10 p.m. Wednesday, 20-year-old Jabbar Gibson modestly confessed that he had commandeered a school bus in New Orleans, then picked up about 70 passengers before heading out for the 13-hour trek to Houston.
Stealing a bus is a felony.
It's also an act of heroism.
There's something about the obliteration of a city and all its survival systems of social support and discipline that messes with moral norms.
When they arrived at the Astrodome, Gibson and his passengers raised another moral question. Should they be let in?
It was reminiscent of the Cold War debates over whether a family with a backyard bomb shelter should, in a nuclear attack, let neighbors in knowing that the food and water supply wouldn't support them all.
Officials believe the practical limit for shelter in the Astrodome is 25,000, and they had made a commitment to house refugees from the Superdome who could reach that number.
At first, unidentified officials told the bus refugees no. But about half an hour later, Red Cross officials who are running the shelter operation let them in to sleep on the former playing field, where the Oilers once slept.
Earlier, however, a desperate woman driving a van filled with five children and a crated dog was turned away. A dramatic photo on the Chronicle's front page yesterday led to phone calls to the newspaper, volunteering shelter.
Officials were reasonably concerned about opening Astrodome gates to all comers before learning how many would be coming from the Superdome. Thursday officials would take a more nuanced approach and let some refugees in who didn't show up in buses.
Meanwhile, fed by alarming images of anarchy from New Orleans and reports of fights breaking out as buses loaded at the Superdome, some Houstonians worried about what kind of trouble was headed our way.
Some nurses at the Texas Medical Center, for example, wondered aloud Wednesday if the refugees would be allowed out of the Astrodome to board the light rail and head their way. They were not alone in their worries.
The answer is yes, the refugees will be allowed to come and go.
But fears that the refugees will become an uncivil mob at the Astrodome are overblown. The concerns were, inevitably, tinged with race and class perceptions. The pictures we see from the Superdome are of people who are mostly poor and black.
Yet imagine that the entire population of The Woodlands, mostly white and prosperous, were confined for five days to an Astrodome that had no air conditioning, few working toilets, no showers, dwindling supplies of food and water, inadequate medical assistance and a likelihood that things would only get worse.
Anyone who thinks they would politely, without anger, queue up for an inadequate number of delayed buses has never driven I-45 during rush hour.
Houston knows the difference between those who steal buses and those who steal televisions, shoot at rescue workers, or who stick up hospital pharmacists for drugs.
We greet these refugees not with zero tolerance, but with a generous welcome. And with an Astrodome that, while not ideal, will be air-conditioned, well-supplied and well-supported.
We can expect that the vast majority will respond the way we ourselves can only hope we would if we were in their soggy shoes.
Curtis Anthony King, a 23-year-old black male, died Friday, June 14, after sustaining blunt force trauma in Santa Monica, according to Los Angeles County coroner's records.
Do you have information to share about the life of Curtis Anthony King? The Homicide Report needs your help. E-mail us at homicidereport@latimes.com.
There are all sorts of ways to promote reading. The latest arrives on Thursday, in the shape of “a Mexican wave starting the day in Australia and, as the sun goes, finishing the day in the United States”. The wave in question is one of pop-up antiquarian book fairs - stalls where passers-by will have the opportunity to buy rare books, prints, manuscripts and ephemera. The organisers, the International League of Antiquarian Booksellers, want you to think of it as “a mixture between bookish flash mob and speed dating for book lovers”.
The project will coincide with the Unesco-backed World Book Day – not to be confused with the UK’s celebration of the same name – and will see more than 25 pop-up fairs across the globe (plus a mobile one, in the form of a campervan selling books on the road from Salisbury to Oxford in the UK). You can find all the information here. Some that stand out at first glance are a woolshed in the Australian bush, a train station in the Netherlands, the top of a Chicago skyscyraper and a microbrewery in Portland, Oregon.
We talked to some of the London exhibitors – where the pop-up at the historic Middle Temple library will be open from noon until 2pm. Most of the books on sale will be priced under £50, in line with the aim to move stock and raise as much money as possible for Unesco, but there will also be some rare and costly gems available. Here are some of our favourite books on offer – but the best finds, as always, are the ones you discover for yourself.
John Le Carré’s espionage classic. Published in London, 1974. Signed by the author.
The English Cricketers’ Trip to Canada and the United States, by Frederick Lillywhite. Published in London, 1860.
The Hours of Marie de Monsoy. Published in France, c1500. With 17 large and 13 small miniatures in a fine fanfare binding.
The Waggoner and Other Poems by English poet Edmund Blunden. A first edition, published in London in 1920. It has the inscription: “Siegfried Sassoon with/ Edmund Blunden’s/ Hallelujahs./ 1 September 1920.” The book is a “testament to the first flourishing of a great literary friendship: Blunden’s book was published with much support and encouragement from Sassoon,” explains Nick McBurney – and this was Sassoon’s own copy, “with a heartfelt inscription from Blunden”.
This book belonged to Austrian archduchess Marie-Louise, Duchess of Parma. Published in Italy, circa 1820.
Rosalind and Helen, A Modern Eclogue: With Other Poems, by Percy Bysshe Shelley. Published in London, 1819.
“Curiously reminiscent of 16th-century Iranian lacquer bindings,” this is a first edition of a collection by one of the great English poets, “on a beautiful but restrained Zaehnsdorf exhibition binding (circa 1900), to an unusual, Orientalist taste,” explains McBurney.
Are you going to one of the fairs? We’d love to see the gems you come across. Photograph them and share them with us via GuardianWitness, by clicking here or on the blue “Contribute” button above.
Nerve activity in the cerebral cortex can drive the growth of deadly brain tumors called high-grade gliomas, new research has found. The finding, from a study of mice with human brain tumors, provides a surprising example of an organ's function driving the growth of tumors within it, according to Michelle Monje, MD, PhD, the Stanford neuroscientist who led the work. The work appears online today in Cell.
High-grade gliomas include tumors that affect children, teens and adults. They are the most lethal of all brain tumors, and their survival rates have scarcely improved in 30 years. Monje's team and others around the world are trying to learn how the tumors arise and grow, with the hope that this understanding will enable development of new drugs that specifically attack the tumors' vulnerabilities.
Monje's team identified a specific protein, called neuroligin-3, which is largely responsible for the increase in tumor growth associated with neuronal activity in the cerebral cortex. Neuroligin-3 had similar effects across the different types of high-grade gliomas, in spite of the fact that the four cancers have different molecular and genetic characteristics.
"To see a microenvironmental factor that affects all of these very distinct classes of high-grade gliomas was a big surprise," Monje said.
The identity of the factor was also unexpected. In healthy tissue, neuroligin-3 helps to direct the formation and activity of synapses, playing an important role in the brain's ability to remodel itself. The new study showed that a secreted form of neuroligin-3 promotes tumor growth.
"This group of tumors hijacks a basic mechanism of neuroplasticity," Monje said.
Blocking the tumor-stimulating effects of neuroligin-3 might be an effective treatment for high-grade gliomas, Monje added.
In the video above, Monje describes some of the earlier work that led her team to ask whether nerve activity could drive tumor growth. In the healthy brain, it's important for neuronal activity to be able to modify how the brain grows and develops, she explains - this is how experience changes our brains. But: "The growth-inducing effects of neuronal activity are very robust and it made me wonder if a similar physiology was being hijacked by glioma cells," she says in the video.