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Lane added the new website, which may keep the domain name “La Jolla By The Sea,” will be merchant-friendly allowing Village businesses ample opportunity to promote themselves and link to their own individual websites, as well as be included in an onsite business directory. He noted the website can easily be adapted to changing technology.
In other matters, Coller said the LJVMA’s budget must be approved by the group and submitted to the city for review by Feb. 1. A vote on approving the proposed budget will take place at the Jan. 11 meeting.
When Will Gilead Sciences' Unlucky Streak End?
Sure, Gilead Sciences has had a lot of bad news lately. The big biotech, though, could probably end that unlucky streak on its own.
If it weren't for bad luck, Gilead Sciences (NASDAQ:GILD) might not have any luck at all.
At least it might seem that way lately for the biotech's shareholders. There has been plenty of bad news with Gilead's announcements in recent months. When will Gilead Sciences' unlucky streak end?
Most recently, Gilead announced disappointing results from a couple of late-stage studies of momelotinib in treating myelofibrosis. In its third-quarter earnings call, the company said that it wouldn't advance GS-5745 in treating Crohn's disease and that eleclazine failed to meet its primary endpoint in a late-stage study for treating long QT-3 syndrome, a rare heart rhythm disorder.
A few weeks earlier, Gilead announced that it wouldn't pursue late-stage studies of GS-4997 in pulmonary arterial hypertension (PAH) or diabetic kidney disease (DKD) after mid-stage failures in both indications. Before that, Gilead canceled its phase 2/3 clinical studies of GS-5745 in treating ulcerative colitis.
These pipeline setbacks are especially concerning because Gilead needs all the help it can get. In addition to the company's seeming streak of bad luck with its pipeline, Gilead is also in the midst of a negative streak of financial results. Sales for Harvoni and Sovalid continue to plunge.
All this bad news has taken its toll on Gilead's stock. Shares are down nearly 30% so far in 2016. Even the election results that helped most biotech stocks haven't been enough to turn things around for Gilead. While Gilead's shares bounced around 8% after the election, the stock has given up around half of those gains.
What will it take for Gilead to break the cycle of bad news? Report some good news. I think that there are three potential ways that the biotech could end its unlucky streak.
First, Gilead could report better-than-expected results for its hepatitis C franchise. Don't expect Harvoni's sales to rebound. That probably won't happen. However, sales growth for new hep C drug Epclusa combined with an end to Harvoni's sales free fall would likely make investors much happier.
Second, Gilead could deliver positive results from its pipeline. At this point, any positive results would be nice. But Gilead really needs something that will be impressive, like overwhelming efficacy from one of its candidates targeting treatment of nonalcoholic steatohepatitis (NASH).
Third, the biotech could make an acquisition that pleases the investment community. Some are rooting for Gilead to buy Incyte (NASDAQ:INCY). Gilead CEO John Milligan particularly mentioned the company's interest in expanding its oncology portfolio. Incyte's Jakafi and strong pipeline of experimental cancer drugs, including epacadostat, could be just what's needed to turbocharge the stock.
The tricky thing with the acquisition game, however, is to buy a company that's a great fit while not paying so much that Wall Street frowns on the deal. My concern with Gilead buying Incyte is that the price tag could be too steep. Personally, I prefer the idea of Gilead making a string of smaller acquisitions.
Gilead doesn't have a lot of control over two of these options for ending its unlucky streak. If the biotech could have stemmed the sales loss for Harvoni already, it would have done so. And there's not a whole lot the company can do about how well pipeline candidates succeed.
However, Gilead can certainly impact its fortunes with a smart acquisition strategy. All signs point to the biotech doing just that. Investors should be encouraged that John Milligan indicated that Gilead would set a high standard for any deals it made.
While Gilead has experienced more bad news lately than good, the company's huge cash stockpile and solid cash flow give it the ability to end the streak. Like famous U.S. general Douglas MacArthur once said, "The best luck of all is the luck you make for yourself."
Organic smoked salmon with sweet and sour shallots, radishes and lemon scented olive oil. When you are ready to serve, pick the shallot rings out of the marinade and scatter liberally over the smoked salmon.
Canadian food blogger Allison Day believes that “life is too short to eat a bad lunch.” The goal of her new cookbook, “Modern Lunch,” is to offer creative ideas for delicious lunches that are budget-conscious and easy to prepare.
RIYADH, Nov 19 (Reuters) - Saudi Arabia's King Salman will inaugurate on Thursday the Waad Al-Shamaal project, a 440-square-km city for mining industries in the country's northern region, Al Arabiya TV said, quoting energy minister Khalid al-Falih.
The project will cost 85 billion riyals ($22.7 billion) and create 10,000 jobs, Falih said. It is part of an industrial scheme aimed at opening up Saudi's north to development that will boost job creation.
Mining is key to the kingdom's reform plan to diversify its economy away from hydrocarbons, as the government aims to more than triple this sector's contribution to the nation’s economic output by 2030.
Saudi authorities estimate the region holds 500 million tonnes of phosphate ore, around 7 percent of global proven reserves, mainly in the Al Jalamid and Umm Wu'al areas between Arar and Turaif.
The energy ministry estimates the kingdom's unused mineral resources to be valued at 5 trillion riyals.
Al Arabiya quoted Falih as saying the mining sector will be open to foreign investment after introducing a new law, without giving further details.
Currently Saudi Ma'aden is the kingdom's sole miner, producing gold and copper and has in recent years expanded into the production of aluminium and phosphates. It is 65 percent owned by the kingdom’s Public Investment Fund.
Ma'aden, which is also the Gulf’s largest miner, was developing its third project to manufacture phosphate fertilisers at its Waad al-Shamal facility at an estimated cost of 24 billion riyals.
Nobody will ever accuse the Hollywood Women's Political Committee of going establishment.
The HWPC, which in 1986 raised more money for Democratic congressional and Senate candidates than any other political action committee, is committed to a wide range of issues involving peace, equality, freedom of choice, civil liberties and conservation.
Following the record-breaking September, 1986, Barbra Streisand concert--which raised more than $1.5 million for candidates and issues campaigns--the HWPC has been making its presence known by interviewing candidates and pushing its specific legislative agenda. And that's not tough to do when you've helped fill a lot of those candidates' coffers.
Now, with the '88 elections ahead, on March 11 the HWPC will present its first award--named for former Texas Rep. Barbara Jordan, who will be the recipient. The night at the Beverly Hills Hotel promises to be the surest shot for big-name stars this side of the Academy Awards. In addition to the film, TV and arts execs who make up the HWPC, star members include Jane Fonda, Morgan Fairchild, Streisand and a new member, author Judith Krantz.
The evening will certainly be an interesting flexing of political muscle--the HWPC having decided that the '86 victories in the U.S Senate and the defeat of the Supreme Court nomination of Robert Bork should be seen as a pushing-off point to a year that they called "the most significant in our history."
CHAI LUNCHEON--She had no plans for a political career, Vermont Gov. Madeleine Kunin told top women supporters of the United Jewish Fund at a luncheon on Wednesday. But she had wanted a flashing red light put at a railroad crossing near her home. "You may start out protecting your children on the way to school . . . and your horizons expand."
Kunin, the third Democrat and the first Jewish woman elected governor in her state, was addressing a crowd of doers as well as contributors, an audience that included Barbara Belzberg, Elaine Goldsmith, Adrea Carter, Terry Bell, Beverly Gelfand and Deborah Rheuban.
"These are women who understand the needs--the needs didn't stop when the stock market crashed," said Bell, who this year heads the Women's Division of Jewish Federation Council.
Many of the women were wearing gold "Lion of Judah" pins, a significant piece of jewelry since it means its wearer has contributed at least $5,000 to the United Jewish Fund that year. And, for each additional year, a diamond is added--at the wearer's cost, Bell explained. "Being here," luncheon chair Beverly Gelfand told the group, "shows that you are committed Jews."
The house where the luncheon was held is itself a symbol of commitment. Sherry and Ernest Goldenfeld have lived at the same Brentwood address for decades--but two years ago, they leveled their old house and built a new one, "big enough," he explained, "so it would be available for all Jewish events. We've had events for the Jewish Homes for the Aging, for Federation . . . "
" . . . and about 20 others that I've attended," Bell finished for him.
Kunin, who kidded that she was also in town "to take away your movie industry"--or to at least persuade some film makers to work in Vermont--said that involvement in politics was, for Jews, a difficult thing. There was for a long time, she explained, "a pogrom mentality . . . sometimes for good reason," that convinced Jews it was better to work behind the scenes, to not draw attention to themselves.
Now, she said, choosing to be politically involved becomes the payment of a debt: "I believe I owe it to them, to those who perished because they didn't have these choices."
LEAP YEAR--OK, since there is an extra day, why not have an extra party. The Music Center is doing just that, with the Feb. 29 Benefactors' Ball. It will honor New Grand Patrons (that means you have given $1 million or more) in addition to New Gold Circle Patrons of the Arts ($500,000 and up). And some lesser big givers too. More details as the ball draws nearer.
COMINGS AND GOINGS--The L.A. Chapter of the Israel Cancer Research Fund has a membership party Sunday at the Hancock Park home of Victoria Bolker. Amy Bolker Stabler is the chair . . . The Beverly Hills home of Richard Colburn is the setting for Monday's concert by the Los Angeles Chamber Orchestra . . . Dr. Dudley Seth Danoff will be honored Saturday at the Century Plaza by the Anti-Defamation League's Medical Division. Dinner co-chairs are Dr. Stuart Holden, Dr. Robert G. Gerber, Steve Meadow and Lou Lenart.
Almost one year after she was robbed at gunpoint in Paris, Kim Kardashian talked in a new interview about how her life changed after the terrifying experience.
“I definitely get a lot more anxiety now, just people knowing your every move,” the Keeping Up With the Kardashians star told T Singapore in an interview published on Monday, September 26.
As Us Weekly reported earlier on Monday, Kardashian is avoiding Paris Fashion Week this year, as will her sister Kendall Jenner.
The Selfish author is a lot more careful about what she posts on social media now, after police said that the robbers planned their heist — stealing more than $10 million in jewelry — with the help of the 36-year-old’s updates on Snapchat and Instagram.
“When you realize you can put a message out there and there’s so many people listening, you look at life differently,” she told the magazine.
The life-and-death situation last year led Kardashian to redefine her priorities, with daughter North, 4, and son Saint, 2, at the top of her list.
While she does post cute pics and videos of her kids online, the reality TV star is also careful about what she chooses to share with fans.
Pope Francis will stamp his personal touch on Easter celebrations starting by washing the feet of young prisoners as he stresses the importance of reaching out to those in need.
The Holy Thursday mass will kick off an intense four days of Easter ceremonies.
The Pope's decision to celebrate Christ's Last Supper in the Casal del Marmo prison in northwest Rome, rather than in St. John Lateran's Basilica as per tradition, may be a hint of a shake-up in keenly observed Easter rituals.
"Holy Week challenges us to step outside ourselves so as to attend to the needs of others: those who long for a sympathetic ear, those in need of comfort or help," he told thousands of faithful gathered on St. Peter's Square.
Francis will begin the day with a solemn chrism mass in St. Peter's Basilica at 0830GMT, before travelling to the prison where he will hold the afternoon Lord's Supper mass with 35 male and 11 female offenders, aged from 14 to 21.
While Bergoglio has washed women's feet in past ceremonies, traditionalists would be riled by such a gesture as they hold that the disciples were all male.
On Friday, Francis will recite the Passion of Christ - the story of the last hours of Jesus' life - in St. Peter's Basilica, before presiding over the Via Crucis ceremony by the Colosseum, where thousands of Christians were martyred in Roman times.
On Saturday, the pontiff will take part in an evening Easter vigil in St. Peter's Basilica.
On Sunday he will celebrate Easter mass in front of tens of thousands of pilgrims in St. Peter's Square, before the Vatican's first non-European pope in nearly 1,300 years pronounces the "urbi e orbi" blessing to Rome and the world.
And yet, owners of Palm Pre (which is a direct competitor to the iPhone) didn't have an (official) Facebook application - until now. The app requires webOS version 1.3.1, and will also work on the upcoming Palm Pixi, but unfortunately, the word is that the app doesn't really have all the latest bells and whistles; in fact, it's very basic compared to the iPhone version.
We don't have a Pre handy, but if you do, and if you decide to try out the app, please let us know your thoughts in the comments.
Three-time world darts champion Martin "Wolfie"Adams with a framed copy of a specially written photo of him and Honarary Freedom of the Parish certificate. Photo by Tim Wilson.
Everyone was a winner at The Deepings School on Tuesday when three-time world darts champion Martin Adams (58) became an Honorary Freeman of Deeping St James.
But “Wolfie” wasn’t the only sports star at Deeping St James Parish Council’s annual parish meeting where Team GB triathlete and top European finisher at last August’s World Sprint Championships, Kayleigh Adams, was also a guest.
Kayleigh, a Bourne Academy student who shares the same birthday as the darts ace, presented awards and certificates to about 20 individuals and groups that had made an outstanding contribution to the life of the area over the past year.
Breaking off from preparing for the European Sprint Distance Triathlon Championships in Geneva, Switzerland, in July, Kayleigh said: “The meeting was really good and it was nice to be able to celebrate other people’s successes.
But the night belonged to Wolfie who was presented with this Honorary Freedom of the Parish certificate by council member Lisa Hughes in front of guests who included prospective South Kesteven District Council leader Bob Adams, chairman Coun Ray Wootten and his wife Linda.
The Deepings World War I Commemoration Group members receive their award for Exceptional Contribution to Village Life, from triathlete Kayleigh Adams (back left) and parish council chairman Coun Andy Pelling. Photo by Tim Wilson.
Martin, who was also presented with a framed copy of a poem written about him by parish councillor Abdrew Bowell, said: “When I won my three world titles, none of them made me speechless.
“But when I opened the letter about this (Honorary Freedom of the Parish), I was quite speechless which is unlike me.
“It’s a fantastic honour, one you don’t expect and I’m very pleased to receive it.
“You’ve got to be aware of representing the place and community where you live, the sport, yourself, your sponsors, the organisation you’re playing within, the television company that’s broadcasting darts and everybody else involved.
It’s a fantastic honour, one you don’t expect and I’m very pleased to receive it.
“There’s nowhere for you to hide, so you have to be a proper professional and I always keep that in mind.
“I love the sport, I love playing and I love going everywhere on the exhibition circuit where I meet so many nice people from all walks of life.
“You could be standing there, one minute, chatting to a millionaire and the next minute, it’s somebody who’s just walked in with a carrier bag to shake your hand.
Coun Phil Dilks, parish council chairman Andy Pelling, Martin "Wolfie"Adams, Kayleigh Adams, district councillors Bob Adams, Linda and Ray Wootten and Judy Stevens. Photo by Tim Wilson.
Before Wolfie’s special moment, a special Exceptional Contribution to Village Life award was presented by Kayleigh to the organisers of Deepings Remembers, a three-day exhibition of World War I memorabilia which drew more than 1,000 visitors to Deeping St James and Market Deeping last November.
Coun Stevens, a member of the Deepings First World War Commemoration Group, said: “We put an exceptional amount of time into remembering, recording and commemorating the War with an event that someone described as being worthy of a city, let alone a set of villages.
Kayleigh also presented the Organisation of the Year Award to the Friends of Deeping Library, Citizen of the Year to Joan Dyke who ran the village playgroup, Meals on Wheels service and still helps out at a weekly Age UK lunch and at Priory Church, Deeping St James.
Meanwhile, Sam Niblock (17) took the Young Citizen of the Year Award for his youth work at the village’s Open Door Baptist Church.
Team GB triathlete Kayleigh Adams and parish council chairman Andy Pelling with Citizen of the Year Award winner Joan Dyke, Young Citizen of the Year Sam Niblock and Liz Waterland, chairman of Friends of Deeping Library which was named Community Organisation of the Year. Photo by Tim Wilson.
Kingfisher Airlines today said the matter was not disclosed to the bourses first as the carrier did not consider it as a "price-sensitive information".
MUMBAI: Facing flak from the exchanges for not informing them about stake sale talks, Kingfisher Airlines today said the matter was not disclosed to the bourses first as the carrier did not consider it as a "price-sensitive information".
The National Stock Exchange and the BSE yesterday had sent letters seeking clarifications from Kingfisher regarding reports about stake sale.
"The company is in talks with foreign carriers as well as domestic investors to sell a stake, pertains to a statement of a very general nature, which in our view can hardly be classified as price-sensitive information, given that these are self-evidently at preliminary stages," Kingfisher informed the National Stock Exchange.
According to Kingfisher, the fact that the company has been attempting to raise much-needed capital over the last two years pursuant to shareholders resolutions approving the same and duly reported to the stock exchanges, has been widely reported in the media for a long time.
"We would like to clarify that even this general non-price sensitive information was shared with the shareholders only as a response to the queries raised by various shareholders regarding equity investment in the company, at the venue of the Annual General Meeting of the company held on September 26, 2012," it said.
Responding to the letter from the BSE, Kingfisher said it is unable to find in the report anything of a price-sensitive nature or information not already in the public domain, attributed to having emanated from the company.
"In any case, it is our humble submission that the company has obligations to the stock exchange regarding dissemination by the company of price-sensitive information and not in the case of information of a general nature in the ordinary course of business, or in respect of information that is already in the public domain," it said.
Shares of the company fell 4.95 per cent to close at Rs 16.12 on the BSE. The scrip dropped 4.72 per cent on the NSE to end the day at Rs 16.15.
Kingfisher owes over Rs 7,000 crore to 17 banks in the long-term debt and has accumulated losses of around Rs 8,000 crore.
The carrier, which is deep in the red, is in talks with its lenders to thrash out revival plan.
Corrections officers at the Centre County Correctional Facility will soon be fitted with body cameras to protect the safety and integrity of jail staff and inmates.
BELLEFONTE — In an attempt to improve safety for both officers and inmates, the Centre County Correctional Facility is going to equip corrections officers with body cameras.
The cameras were already approved by the prison board and after a year of trials at the jail, the county has agreed to enter into a contract with Axon Enterprises to use its camera system for five years. The contract was reviewed by the county commissioners during the Feb. 5 board meeting, and will be placed on the consent agenda for Feb 12.
According to CCCF Warden Christopher Schell, the cameras will supplement the video security surveillance that is already in the facility, but which does not show into the inmate’s cells.
The cameras will be worn by the two lieutenants on duty during the day shift and evening shift, along with four officers on the floor who typically respond to code violations. The cameras have a 30-second relapse, and when an officer taps the camera twice, it will begin recording from the 30-second relapse until the incident is over.
Schell said the camera footage is a great learning tool to highlight and share the correct ways to do things and to discuss any issues that may have occurred during an incident.
The contract the county will enter into costs $11,445 for the first year and $4,914 each year thereafter, and includes the equipment maintenance and software licensing for the cameras. Every 30 months, the company will provide new equipment to keep the jail up to date.