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She will be one of three female Fed regional bank presidents. She is also the first lesbian to hold a Fed policymaking post.
John Williams's performance review apparently went really well. Others...less so.
It's basically a non-event (for us).
The presidents of the Cleveland and San Francisco have better things to do than placate the alarmists, like clean the crud out from under their fingernails.
We all know what's inside J-Yell's metal suitcase this time.
She's not as low-rate as President Trump thought.
Because, for starters, most Americans don't know who runs the Fed.
He killed his girlfriend Reeva Steenkamp in February 2013 after shooting her four times through a locked door.
He is currently under house arrest after spending a year of his five-year sentence in jail for a crime of culpable homicide (manslaughter).
Prosecutors had appealed against the original verdict to try to achieve a murder conviction.
Pistorius will now have to return to court for a new sentence to be decided.
South Africa's Supreme Court of Appeal ruled that the lower court did not correctly apply the rule of dolus eventualis - whether Pistorius knew that a death would be a likely result of his actions.
Reading the ruling reached by a panel of judges, Justice Lorimer Leach said that having armed himself with a high-calibre weapon, Pistorius must have foreseen that whoever was behind the door might die.
Justice Leach compared it to someone setting off a bomb in a public place not knowing who the victims might be.
He added that Pistorius did "not take that most elementary precaution of firing a warning shot".
Pistorius' lawyer argued that he believed that there was an intruder in the house but the judge said that the identity of the person behind the door was irrelevant.
The minimum sentence for murder is 15 years but judges can apply some discretion.
South African law does not make provision for someone to be placed under house arrest for more than five years, so Pistorius will be going back to prison, the BBC reports.
The double amputee was released from prison on 19 October. Under South African law, he was eligible for release under "correctional supervision", having served a sixth of his sentence.
Pistorius can challenge the ruling in the constitutional court but only if his lawyers can argue that his constitutional rights have been violated.
Pistorius did not attend the hearing in Bloemfontein.
But Ms Steenkamp's mother, June, was present and afterwards she was seen outside the court being embraced by members of the African National Congress Women's League, who were singing songs of celebration.
What will happen to Oscar Pistorius?
Will he return to jail?
Yes. He will be back behind bars, less than two months after he was placed under house arrest.
When will he be sentenced?
We don't have a date yet, but it will be next year. The minimum sentence for murder is 15 years, but the judge does have the discretion to lower it.
Yes, but only if his lawyers are convinced that the appeal judges violated his constitutional rights. So it's a high threshold, and hard to meet.
So is this the end of Pistorius' professional athletics career?
Almost certainly. He's 29, and will be past his prime by the time he is freed. It is also unlikely that advertisers would want to sponsor him, as the Pistorius brand is now tainted.
South African star athlete Oscar Pistorius will not be released from prison on Saturday as expected.
Physicists Geoffrey West and Luis Bettencourt of the Santa Fe Institute have looked at data from cities around the world to try to understand what, exactly, they are. They've found that surprising patterns underlie the growth of all urban systems.
Read more on their research here.
When Exactly Was America Great?
How Do We Make Rules for Self-Driving Cars?
A family was stunned when a man they had been mourning turned up at home two months after his funeral.
Ironically, Aigali Supugaliev’s niece ‘almost collapsed with a heart attack’ when she saw her ‘dead’ uncle alive and healthy.
The 63-year-old had been reported missing from his home in Tomarly, Kazakhstan on July 9.
Two months later, a DNA test on a decomposed corpse near his home found a 99.92% likelihood it was Mr Supugaliev – the highest probability the test could give.
In fact, without telling his family the missing man had taken up a four-month job on a distant farm.
After his relatives held a funeral and buried the remains, he returned home – later posing with his own gravestone.
His brother Esengali Supugaliev said: ‘When Aigali came home alive and healthy, my daughter Saule, seeing her ‘dead’ uncle, almost collapsed with a heart attack.
‘The DNA analysis had confirmed this was my brother. We believed the results and conducted all the funeral and memorial rites.
The DNA test on the body used the dead man’s nail clippings, according to local reports.
Akmaral Zhubatyrova, the scientist who carried out the test, said: ‘It is impossible to state unequivocally that this is the body of a person, relying only on the results of the DNA examination.
GEORGETOWN, Guyana,CMC – Promising Pakistan stroke-maker Babar Azam has been named to replace injured Australian batsman Chris Lynn in the Guyana Amazon Warriors squad for the upcoming Caribbean Premier League which bowls off next month.
The 22-year-old right-hander has been successful across all formats, scoring consistently since his international debut two years ago.
Babar Azam … replaces Chris Lynn in Amazon Warriors.
Head coach Roger Harper said Azam would be the ideal replacement for Lynn, who was expected to be a key figure in the franchise’s title bid.
“We are hugely disappointed to lose the talent of Chris Lynn to shoulder injury, he was the leading scorer last year and we were happy to have him back,” Harper said.
“However, we are extremely delighted in getting a world-class replacement in Babar Azam. He is one of the most exciting batsmen in the world and we are sure that he will be a huge success for us at Hero CPL 2017.” Azam averages 50 in both the Twenty20 and One-Day Inernational formats, where he has become a prized asset for Pakistan.
He came to the fore in earnest last year when he struck hundreds each game of a three-match series against West Indies in United Arab Emirates.
Last April, he struck another hundred against West Indies in the second ODI here at the National Stadium at Providence.
The time of day determines a muscle's energy efficiency and metabolic response.
Northwestern Medicine scientists have discovered circadian clocks in muscle tissue that control the muscle's metabolic response and energy efficiency depending on the time of day.
The finding in mice sheds light on the time-of-day differences in muscle's ability to adapt to exercise and use oxygen for energy. Muscle cells are more efficient during an organism's normal waking hours, the study found.
All cells in the body, including those in muscle, contain a clock that regulates how cells adapt to changes in the environment and activity across the 24-hour day.
"Oxygen and the internal clock are doing a dance together inside muscle cells to produce energy, and the time of day determines how well that dance is synchronized," said senior author Dr. Joseph Bass. "The capacity for a cell to perform its most important functions, to contract, will vary according to the time of day."
More research is needed before the finding can be translated into workout advice.
"We're not saying we can tell athletes when they should work out," Bass said, "but in the future, perhaps, you may be able to take advantage of these insights to optimize muscle function."
Bass is the Northwestern Medicine chief of endocrinology, metabolism and molecular medicine, and director of the Center for Diabetes and Metabolism at Northwestern University Feinberg School of Medicine. He also is a member of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University.
Clara Bien Peek, the first author and a research assistant professor, spearheaded the work on muscle and timing.
The paper has been published in the journal Cell Metabolism.
The research has implications beyond muscle cells because oxygen response is important in all cells. In particular, the deprivation of oxygen is a key factor in heart attacks and in cancer, in which the depletion of oxygen curiously enables cancer cells to grow.
In the research, scientists performed studies in mice, which were exercised on a treadmill at different times of day, as well as in isolated muscle fibers in which the circadian clock was genetically mutated.
The scientists analyzed mouse muscle tissues and muscle fibers for expression of genes that are important for exercise. In this way, they determined the impact of deregulation of the circadian clock on muscle fibers in terms of how muscle processes fuel, like sugar and fat, when oxygen levels are low.
"When we manipulated the clock genetically, we noticed there were profound abnormalities in the muscle," Bass said. "That set us on a course to understand how the inner muscle clock is important in regulating how well the muscle cell can mobilize energy."
When mice, which are nocturnal, are exercised during the night, their muscles are better at turning on genes to help them adapt to exercise, scientists found. Since these genes also exist in humans, this suggests humans may also be able to respond better to exercise during the daytime.
Normally when we rest or do low-level exercise, our muscles consume oxygen to make energy. When we start to sprint or exercise strenuously, we consume oxygen faster and quickly run out. That's when the dip in oxygen triggers HIFs and signals muscles to switch to sugar for energy - which in turn increases lactic acid.
Turning off the muscle clock prevented the normal capacity of exercise to induce sugar consumption and generation of lactic acid. These findings suggest that better exercise capacity may be tied to specific times of day.
"In the future, we may discover new ways to manipulate the oxygen response of the cell by resetting the clock," said Bass, who also holds the Charles F. Kettering Professorship of Medicine at Feinberg. He noted drugs are available that can manipulate the internal clock in cells.
"If we can optimize muscle function, " he said, "it's also a critical step in understanding how to impact glucose metabolism in diabetes."
Diabetes is characterized by a failure of muscle to consume glucose, which in turn controls blood sugar levels. Strengthening the muscle clock may provide a new way to eliminate excess glucose and treat diabetes.
The scientists tested their theories about the internal clock in muscle cells because those cells are particularly dependent on oxygen for contraction and metabolism.
"We wanted to determine the rules that interconnect clocks with the physiological use of oxygen," Bass said. "We believe that studying muscle can provide us with the rules of how clocks govern response to oxygen, and we would like to test these principles in a variety of conditions."
The study was supported by National Institutes of Health grants R01DK090625, R01DK100814 and K01DK105137-02 from the National Institute of Diabetes and Digestive and Kidney Diseases and grant P01AG011412 from the National Institute on Aging. Lynn Sage Cancer Research Foundation and others also supported the study.
Article: Circadian Clock Interaction with HIF1α Mediates Oxygenic Metabolism and Anaerobic Glycolysis in Skeletal Muscle, Clara Bien Peek, Daniel C. Levine, Jonathan Cedernaes, Akihiko Taguchi, Yumiko Kobayashi, Stacy J. Tsai, Nicolle A. Bonar, Maureen R. McNulty, Kathryn Moynihan Ramsey, Joseph Bass, Cell Metabolism, doi: 10.1016/j.cmet.2016.09.010, published 20 October 2016.
Medicine, Northwestern. "Muscles have circadian clocks that control exercise response." Medical News Today. MediLexicon, Intl., 24 Oct. 2016. Web.
Bitcoin rose around 30 percent in one month following Jamie Dimon's speech, where he also compared the currency to tulips bulbs in a reference to the famous market bubble from the 1600s.
JPMorgan chief executive Jamie Dimon regrets having called bitcoin a "fraud" but would still not be interested in the cryptocurrency, he said in an interview on Fox Business on Tuesday. Dimon, known for his candid comments, slammed the viability of bitcoin in September. "The currency isn't going to work. You can't have a business where people can invent a currency out of thin air and think that people who are buying it are really smart," he had said at a conference.
The buzz generated by Dimon's comments spurred more interest in the alt-currency. Bitcoin rose around 30 percent in one month following Dimon's speech, where he also compared the currency to tulips bulbs in a reference to the famous market bubble from the 1600s.
Dimon's comments were followed by a more tempered view from chief financial officer Marianne Lake, who said the bank was "very open minded to the potential use cases in future for digital currencies that are properly controlled and regulated." Despite Dimon's criticism, several banks, exchange operators and companies eagerly embraced bitcoin, sparking a spectacular rise in the cryptocurrency. On Tuesday, bitcoin was down nearly 5 percent at $14,202 in early trading. It traded at $909 a year ago and breached $19,000 in December.
Exchange operators such as CME Group Inc and Cboe Global Markets Inc opened their platforms to allow bitcoin futures trading, while Square Inc rolled out a bitcoin buying/selling feature on its app to a select few. Dimon and Lake, however, have commended blockchain - the technology used by bitcoin and other digital currencies - a view echoed by Citigroup Inc CFO John Gerspach and many others across the industry.
"Blockchain is real. You can have crypto yen and dollars and stuff like that," Dimon told Fox.
DETROIT — The Giant shadow of this World Series belongs to Melky Cabrera.
Do the Giants even win the NL West this year without his MVP-level production prior to being suspended 50 games for having an elevated testosterone level? Does the NL team — his Giants — get the home-field advantage and, thus the first two games in AT&T Park if he is not the All-Star Game MVP?
Even this postseason, the suspension completed, there were calls to re-instate Cabrera to the roster. The Giants rejected that because they did not want to mess with what has, in Cabrera’s absence, turned out to be a surprisingly strong offense and a roster with such positive energy/chemistry — a roster that was not thrilled Cabrera vanished without offering teammates a mea culpa.
Yet, when you ask outside executives where Cabrera will end up next year, one locale that is repeated is San Francisco. In fact, even Giants officials privately concede the possibility.
They have Angel Pagan coming up to free agency and — cover your eyes, Mets fans — his success, especially after Cabrera’s departure, might have priced him out of San Francisco. One NL personnel head went as far as to say he thinks Pagan, because of his trajectory and prime center field position, will receive more than Nick Swisher in free agency.
Cabrera is one of the most interesting free-agent cases this offseason. One NL official summed it up this way: “He was a pretty good player with the Yankees, fat and terrible for Atlanta, very good last year [for Kansas City] and unbelievable this year. Who is the real guy? I saw him in the minors and I thought he was an extra outfielder. I have hard time going out of my way to reward a guy trying to break the system as badly as this guy did.
Cabrera not only failed a drug test, at least one associate tried to create a fake website for a supplement company to contrive a cover story that Cabrera’s positive results were from a tainted supplement. So teams definitely will investigate him in a significant way. Still, morality will not stand in the way of most clubs adding offense, especially if the offense is a bargain.
After the All-Star Game, there was talk Cabrera, a 28-year-old switch-hitter, would command a five-year contract worth as much as $75 million, maybe more. But in the group of executives with whom I spoke, one thought Cabrera could get two years at $10 million to $12 million, another said one year at $8 million to $10 million. But the large majority saw Cabrera having to take a one-year deal in the $2 million-to-$5 million range. He will have to use 2013 as a forum to prove he is a quality player.
The Mets were one club that came up regularly as a potential landing spot for Cabrera, as were the outfield-needy Phillies. The Mets need outfielders and don’t have a ton of money to address their severe needs there. So if they could bag Cabrera as corner outfield insurance against Jason Bay and Lucas Duda, it could make sense, especially if they are unable to retain Scott Hairston. Probably at his worst, Cabrera would be a motivated fourth outfielder who always could hit righties well, with the possibility he is more than that if any of the improvements of the past two years are real.
The Yankees? Well, they did offer Cabrera a minor league pact after he was released by the Braves following the 2010 season. They will be looking to replace Andruw Jones as an outfielder who specializes in hitting southpaws. Yankees officials never viewed Cabrera as a negative influence on Robinson Cano, as some outside the organization did. Still, Cano ended up being smeared with allegations this season because of the association, so the Yankees might be hesitant to reunite the pair. Plus, Cabrera might not see the certainty of playing time with the Yankees that he needs to rebuild his value.
In an age of more information and sensitivity about head trauma injuries, there was concern Tigers starter Doug Fister was permitted to stay in Game 2 after taking a liner off his head. The drive, off the bat of Gregor Blanco, continued into center field. However, Detroit trainer Kevin Rand insisted the blow “looked worse on TV” and that essentially the ball continued into center field because it skimmed the righty’s head rather than striking it solidly.
* The Mets are desperate to find power at minimal costs this offseason and at no position more than catcher, where their five homers last season were by far the fewest in the majors.
One name to keep an eye on is Miguel Olivo. who is someone they are eyeing this offseason. When the Mets made their priority trade list in July, the Rockies’ Ramon Hernandez was on top for catchers, but Olivo was among the secondary candidates along with Kelly Shoppach, whom they ultimately obtained. But the indications I have received are the Mets are unlikely to retain Shoppach.
The Mariners recently announced they would not pick up Olivo’s $3 million 2013 option. He is far from a perfect candidate; his .239 on-base percentage last season was the worst in the majors (minimum 300 plate appearances) since Corey Patterson’s .238 in 2008. Still, playing in a tough home park for long balls the past two seasons in Seattle, Olivo hit 31 homers. He has reached double digits every season since 2006, a period when only Brian McCann (151) and Mike Napoli (120) have more homers by a catcher than Olivo (112).
Joseph Tsai would be the third lease holder of the Coliseum since 2013.
The Coliseum sold out all of its 40 VIP boxes for this week’s event.