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Online Application – the form is similar for initial certification. There is a box to check at the top that indicates renewal. The certification checklist must be consulted for other documentation to be submitted. Self-Assessment form – this is based off of the four pillars of formation from Co-Workers in the Vineyard of the Lord. The fifth section is based off of the particular ministry specialization you are renewing. Enrichment log – to document all ongoing formation since initial certification.
{ "timestamp": "2019-04-26T13:58:52", "url": "https://www.aod.org/being-catholic/leadership-formation/renewal-of-certification/", "language": "en", "source": "c4" }
Tap. Tap. Tap. Is this thing still on? This is just life right now but I am getting into the swing of things and wanted to drop in and say HELLO again. With the school year around the corner we are all in full swing lamination mode, prepping, and getting back into our old classrooms. The 4th of July is a signal that school is slowly but surely coming toward us. It's exciting! I love fresh starts! Not only am I checking in to see if anyone reads this blog (hi mom! hi best friends!) but also to ask a question. Many of us send emails or newsletters out--it's a great way to keep parents informed but sometimes I feel that as the school year goes on those emails don't get read at all. So what do you do to make sure the parents are actually reading the emails and newsletters? Have you had that "Bueller" moments where it's like...did you get my email? Now, I completely understand that parents have busy lives and the email quickly gets archived or is ignored because of so much going on in life. Some of my parents have multiple kids and can't keep up with the emails--their inboxes are inundated. I try to really send information packed emails and communicate that with parents at the beginning of the year. I'm all about quick and efficient emails but I don't want to email so often that parents dismiss the content completely because they might miss something important. One trick I have learned is within the contents of the email I write to parents to place a star, or smiley face, or write down a random fact about themselves inside their child's planner (another one of our communication tools) for some simple reward for their child. I also tell my students that their parents need to read their email--because after all, aren't persistent 11 year olds a really good shot at making sure something gets done? YES. They are! They never let me forget the extra two minutes of recess I owe them. Every minute counts. Back to the reward...The rewards range from a sweet treat to a homework pass to whatever I fancy--but there is a reward of some kind. And it works! I love the results that I get and I genuinely feel that my parents are in the loop--which is always a good thing--and they know that the lines of communication are open! So what is it that you do? I have a back and forth planner that parents initial with homework assignments and behavior records. Do you email? Does anyone use google forms? I am so curious and want to hear what my friends are doing! Is paper the way to go? Emails? Super techy and teachy people that use fancy apps, is there anything out there? Let me know!
{ "timestamp": "2019-04-22T02:04:10", "url": "http://www.theteachyteacher.com/2015/07/youve-got-mail.html", "language": "en", "source": "c4" }
Hoje fiz 37 aninhos e esta é uma das minhas fotografias favoritas ...quem não se lembra do elefante do Jardim Zoológico de Lisboa a tocar o sino quando recebia uma moedinha? Uma das vantagens de fazer 37, é ter muitas e boas memórias! I am 37 years old today and this is one of my favourite photos of all time...who (in Portugal) doesn't remember the elephant from the Lisbon Zoo that rand a little bell everytime he received a little coin? One of the advantages of being 37 is that I have many, and good memories! moreie en lisboa quando era pequena, mais nuca foi ou zoo.. Microsof company affirms Microsoft kinect will estimation specific exercising information as well as people can offer "optional workout features, as if your elevation, fat, get older and gender" to further improve the actual application's exactness.
{ "timestamp": "2019-04-25T02:17:23", "url": "http://boladeberlin.blogspot.com/2014/09/37.html", "language": "en", "source": "c4" }
Destinations to Florida, Bahamas, and southern California are just a click away, but you better hurry because 13 routes are already sold out. Obviously some limitations apply. You must book your flight today by 4pm EST for travel between 1/21/15-2/11/15. Here's the link, now go to the Bahamas.
{ "timestamp": "2019-04-19T03:28:04", "url": "https://jalopnik.com/jetblue-wants-you-to-stay-warm-with-32-flights-1680947019", "language": "en", "source": "c4" }
Gorvagh Community Centre Committee secured LEADER funding to replace the roof, install external doors and a window and all associated works at Gorvagh Community Centre. The old roof was in place since 1936 and leaks had developed. With LEADER funding the committee carried out the repairs which were vital for the sustainability of the building. Gorvagh Community Centre can now continue to be the heart of the community-a focal point for young and old to socialise, learn new skills, access information and enjoy community events.
{ "timestamp": "2019-04-23T09:51:53", "url": "http://www.ldco.ie/gorvagh-community-centre-upgrade.html", "language": "en", "source": "c4" }
In organic chemistry, a diene (/ˈdaɪ.iːn/ DY-een) or diolefin (/daɪˈoʊləf[invalid input: 'ɨ']n/ dy-OH-lə-fin) is a hydrocarbon that contains two carbon pi bonds. Conjugated dienes are functional groups, with a general formula of CnH2n-2. Dienes and alkynes are functional isomers. Dienes occur occasionally in nature but are widely used in the polymer industry. Cumulated dienes have the double bonds sharing a common atom as in a group of compounds called allenes. Conjugated dienes have conjugated double bonds separated by one single bond. Unconjugated dienes have the double bonds separated by two or more single bonds. They are usually less stable than isomeric conjugated dienes. Compounds that contain more than two double bonds are called polyenes. Polyenes and dienes, share many of their properties. Some dienes: A: 1,2-Propadiene, also known as allene, is the simplest cumulated diene. B: Isoprene, also known as 2-methyl-1,3-butadiene, the precursor to natural rubber. C: 1,3-Butadiene, a precursor to synthetic polymers. D: 1,5-Cyclooctadiene, an unconjugated diene (notice that each double bond is two carbons away from the other). E: Norbornadiene, a strained bicyclic and unconjugated diene. F: Dicyclopentadiene. G: Linoleic acid, a fatty acid that is required in the human diet. An important reaction for conjugated dienes is the Diels–Alder reaction. Many specialized dienes have been developed to exploit this reactivity for the synthesis of natural products, e.g. Danishefsky’s diene.
{ "timestamp": "2019-04-18T23:06:14", "url": "https://simple.wikipedia.org/wiki/Diene", "language": "en", "source": "c4" }
The Basel III framework developed in the aftermath of the financial crisis has made fundamental changes in regulatory capital requirements applicable to banks and other financial institutions. Risk weightings of securitization have come into particular focus as part of this exercise, with the Basel Committee finalizing its securitization framework at the end of 2014 which comes into effect in 2018. Both the EU and the US have also finalized their approach to securitization risk retention with a somewhat different approach between the two regimes. There have also been recent efforts, including as part of the EU’s Capital Markets Union initiative to seek to reinvigorate the securitization market, including a more favorable capital framework for simple and transparent securitizations. This seminar will consider all these developments and the effect of the differences in approach between the EU and the US.
{ "timestamp": "2019-04-20T02:22:38", "url": "https://www.mofo.com/resources/events/securitization-risk-weightings-and-risk-retention-approaches-in-the-eu-and-us.html", "language": "en", "source": "c4" }
When I tell people that the present situation resembles the 1970s, they immediately think of July 1979, when Jimmy Carter gave his famous “malaise” speech on national TV. The stock market had been dead for six years, and blue chip U.S. stocks had price-earnings multiples in the single digits. The CPI was rising at double-digit rates, and interest rates were galloping higher to keep up. “It’s not that bad,” people say today. But I’m not thinking of 1979, I’m thinking of 1973. And it’s true, it’s “not that bad.” It’s worse. Where are we on the dollar devaluation timeline today, compared to the 1970s? In the 1950s and 1960s, the dollar was pegged to gold at $35/oz. In the 1980s and 1990s, the dollar floated, but its value stayed fairly stable around $350/oz. In 1971, the dollar’s link to gold was destroyed, and the dollar devaluation began. In May of 1973, it hit $95/oz for the first time. This roughly equivalent to where we are today, having gone from $350/oz. to about $950/oz. When Jimmy Carter was making his speech, the dollar was in its last great collapse, to a nadir of 1/850th oz. of gold just seven months later. The equivalent today would be a move to $8,500/oz. of gold. The S&P 500 peaked in January 1973, so mid-May 1973 was about five months after the peak. This was the start of the horrible 1973-1974 bear market. The S&P 500 most recently peaked in October 2007, so mid-March 2008 is about five months after that peak. However, we seem to have diverged quite a bit from the 1973 script. Arthur Burns, the Fed’s Chairman in 1973, might be nicknamed “Easy Art” today for his efforts to get the economy going again in 1971. His cheap-money, low interest-rate policies started the trend of 1970s devaluation. However, by May 1973, he was already getting nervous. Commodity prices were soaring, and the dollar’s value kept sinking against gold. The economy was roaring. The Fed funds rate ended 1972 around 5.3%, but by May 1973 it was already up to 7.84%. In July 1973, it averaged 10.40%. It was primarily this increase in interest rates – an effort by a hawkish Fed to stop the devaluation trend – that led to the breakdown of the stock market. Combined with the inflation, the economy crumbled soon after. It is safe to say that the Fed will not be at 10%+ in a couple months. The ECB was recently termed “ultra-hawkish” in the U.K.’s Telegraph newspaper, for a policy of keeping a 4.0% rate unchanged. Today’s breakdown in credit markets, caused by a lending binge that did not exist in the early 1970s, has effectively eliminated any chance of serious inflation-fighting activity. Ah, the bulls say, but certainly that is a positive, no? The Fed is expected to cut rates further. The two-year U.S. Treasury bill yields less than 2.0%. The deteriorating economy is expected to put a lid on inflation. But in economics, two wrongs don’t make a right. With Ben Bernanke pouring gasoline on the dollar pyre in an effort to warm up “frozen” debt markets, the inflation in coming years may well exceed that of the 1970s. People may look back on the 11.2% increase in the official CPI in July 1979, from a year earlier, and laugh that such a wimpy figure could be considered “malaise.” On top of that, the credit breakdown and housing collapse will do whatever additional damage they have left to do. Most people didn’t even have credit cards in the early 1970s, much less a debit card that makes withdrawals from 401(k) plans. The Fed’s lower interest rates haven’t helped the situation much. But then, today’s problems were not caused by rates that were too high. Were lower rates ever really the point? The dollar’s slide may not be just an unfortunate side effect, but the real goal of the Fed’s easy policy. You could argue that, today or in the 1930s, a devaluation would have made debts easier to pay back, by inflating workers’ salaries and other prices. Ben Bernanke himself has made this argument, in a coy way. Unfortunately, the Fed is finding that today’s credit-collapse recession is indeed “putting a lid on inflation” – namely a rise in wages – while inflation of household expenses continues unabated. The resulting squeeze on household budgets has made debt service even more unlikely. Whoops! If there’s a lesson to be learned from the 1970s, it is that even a hawkish Fed and 10%+ interest rates are not a reliable solution to currency decline. Neither Easy Art nor Hawkish Art produced a healthy economy. The real problem, in the 1970s, was that the dollar left its golden anchor. The real problem, today, is that it never went back. The credit collapse recession is grabbing all the headlines now, but in six years, when Barack Obama appears on TV wearing a sweater, with a new batch of government solutions to the $600/barrel oil price, will we even care? By that time, I think people will be ready to do what should have been done many years ag repeg the dollar to gold. No more of this floating currency, inflation/devaluation, Fed manipulation nonsense.
{ "timestamp": "2019-04-25T12:37:58", "url": "https://newworldeconomics.com/worse-than-1973/", "language": "en", "source": "c4" }
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Home » Stock » Chipotle Mexican Grill Stock » CMG Stock: This Is Why the Bears Are Wrong on Chipotle Mexican Grill, Inc. Chipotle Mexican Grill, Inc. (NYSE:CMG) just reported first-quarter earnings and it wasn’t pretty. In fact, it was the burrito chain’s worst quarter ever, as the company suffered its first-ever quarterly loss. Investors were hitting CMG stock hard Wednesday morning, with the stock down nearly five percent. And since the start of a number of food safety incidents that began last October, CMG stock is down about 42%. However, there’s still a lot to like about Chipotle Mexican Grill. Let me explain. After the bell on Tuesday, Chipotle reported a loss per share of $0.88 for the first quarter. That’s a huge plummet from the profit of $3.88 per share a year earlier. Profit was largely hurt by the company’s aggressive attempt to lure customers back. Chipotle gave away more than six million free burritos, as well as nearly one million free orders of chips and salsa. Same-store sales plunged 29.7% for the quarter, which is a bit more than analysts’ expectation of 28.4%. But there just might be some good news. Same-store sales for the first three weeks in April declined 22%. This compares to January, which was the height of the foodborne illness outbreak at the chain, when the company reported same-store sales plunged 36%. Chipotle also recently reported declines of 26.1% and 24.4% in same-store sales in February and the first two weeks of March, respectively. So the good news is that customers are returning to restaurants—they’re just not returning as quickly as impatient investors would like. There’s a bit more good news. The earnings loss is not as bad as analysts were expecting. According to Thomson Reuters, analysts were expecting an even steeper loss of $0.95 per share. (Source: “Chipotle freebies fail to overcome food safety fears; shares fall,” Reuters, April 26, 2016.) And for the second quarter, things should get better on the earnings front, as Chipotle CFO Jack Hartung said the company does not expect a loss in the second quarter of this year. Bears have hit CMG stock hard and they are reacting as if this is the end of Chipotle. Or at the very least, they have the mindset that Chipotle’s customer visits won’t return to their same levels prior to the outbreak. This is just wrong. Sales trends are continuing to improve and they should keep improving as the year continues. As long as Chipotle doesn’t suffer another outbreak, it should have no problem achieving this. But it may take a while before Chipotle returns to the peak same-store sales of $2.5 million per restaurant that the company reached before the foodborne crisis. (Source: “Chipotle's Best-Case Scenario Is Recovery by 2018, Wedbush Says,” Bloomberg, March 29, 2016.) It may not even achieve this for two or three years. Nevertheless, the point is that Chipotle should get back to those levels eventually. In fact, in a recent report, JPMorgan analyst John Ivankoe noted that Chipotle’s food safety issues have cost the burrito chain three years of earnings growth. He said that Chipotle’s earnings should reach 2014 levels by 2017, and he also believes that Chipotle will return to 20% or more earnings growth by fiscal 2018. (Source: “Chipotle Mexican Grill, Inc. Upgraded Ahead Of Earnings,” ValueWalk, April 14, 2016.) In the meantime, Chipotle is continuing to add new restaurants, which should help fuel its top and bottom lines a bit. Chipotle says that margins will begin to improve and should gradually approach levels seen before the foodborne outbreak. Chipotle also has more than this going for it. The company still has lots of room to expand in the U.S. as well as internationally. And apparently, according to a patent filing, the company is looking to start a burger business. Things look kind of bleak right now for Chipotle Mexican Grill. However, sales are steadily improving and the company still has a lot of upside for growth over the next few years. With the stock having been absolutely hammered over the last few months, this may be a good opportunity for investors to take a look at CMG stock. CMG Stock: This Is Why the Bears Are Wrong on Chipotle Mexican Grill, Inc. Chipotle Mexican Grill, Inc. (NYSE:CMG) just reported first-quarter earnings and it wasn’t pretty. In fact, it was the burrito chain’s worst quarter ever, as the company suffered its first-ever quarterly loss. Investors were hitting CMG stock hard Wednesday morning, with the stock down nearly five percent. And since the start of a number of food safety incidents that began last October, CMG stock is down about 42%. However, there’s still a lot to like about Chipotle Mexican Grill. Let me explain. After the bell on Tuesday, Chipotle reported a loss per share of $0.88 for the first quarter. That’s a huge plummet from the profit of $3.88 per share a year earlier. Profit was largely hurt by the company’s aggressive attempt to lure customers back. Chipotle gave away more than six million free burritos, as well as nearly one million free orders of chips and salsa. Same-store sales plunged 29.7% for the quarter, which is a bit more than analysts’ expectation of 28.4%. But there just might be some good news. Same-store sales for the first three weeks in April declined 22%. This compares to January, which was the height of the foodborne illness outbreak at the chain, when the company reported same-store sales plunged 36%. Chipotle also recently reported declines of 26.1% and 24.4% in same-store sales in February and the first two weeks of March, respectively. So the good news is that customers are returning to restaurants—they’re just not returning as quickly as impatient investors would like. There’s a bit more good news. The earnings loss is not as bad as analysts were expecting. According to Thomson Reuters, analysts were expecting an even steeper loss of $0.95 per share. (Source: “Chipotle freebies fail to overcome food safety fears; shares fall,” Reuters, April 26, 2016.) And for the second quarter, things should get better on the earnings front, as Chipotle CFO Jack Hartung said the company does not expect a loss in the second quarter of this year. Bears have hit CMG stock hard and they are reacting as if this is the end of Chipotle. Or at the very least, they have the mindset that Chipotle’s customer visits won’t return to their same levels prior to the outbreak. Sales trends are continuing to improve and they should keep improving as the year continues. As long as Chipotle doesn’t suffer another outbreak, it should have no problem achieving this. It may not even achieve this for two or three years. Nevertheless, the point is that Chipotle should get back to those levels eventually. In the meantime, Chipotle is continuing to add new restaurants, which should help fuel its top and bottom lines a bit. Chipotle says that margins will begin to improve and should gradually approach levels seen before the foodborne outbreak. Chipotle also has more than this going for it. The company still has lots of room to expand in the U.S. as well as internationally. And apparently, according to a patent filing, the company is looking to start a burger business.
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Get ready to look your Sunday best this Easter! Featuring soft purple hues of velvet, lavender and tanzanite with a new, “bubble” shape, our Limited Edition Easter Swarovski® Crystals Stardust Pack adds extra-sparkle to your springtime Living Locket® look! 5 Purple Velvet, 5 Provence Lavender, 5 Tanzanite, 5 Crystal Bubble Swarovski® Crystals.
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Everyone deserves a healthy environment, where they live, learn and play. Below are some actions you can take to make your indoor environment healthy and safe. Mold problems are moisture problems. When moisture enters your home it creates a welcoming environment for pests and mold, both of which can lead to respiratory problems. Keeping your home dry will help prevent these problems and provide a safe, clean environment for you and your family. Click here for more about mold prevention and cleanup. Do you know what's in the dirt inside your home? Dirt contains lead dust, pllen, pesticides, insect fragments, and lots of other contaminants. The first four steps you take inside your front door bring in close to 85% of the outdoor contaminants found indoors. The best ways to reduce outdoor contaminants are to add doormats and remove your shoes. Research suggests that we spend about 90% of our time indoors, and almost two-thirds of that time is in our homes! A clean home means less exposure to contaminants, less clutter, and a more comfortable living environment for you. Clean floors and surfaces regularly with a damp mop and microfiber cloth. Use a HEPA vaccuum. If that doesn't fit your budget, use a vaccuum with a HEPA air filter and vacuum often. Add doormats by all exterior doors. Remove your shoes and leave them by the door. Reduce clutter. So you are not overwhelmed, start in one room and remove one-third of the clutter. A well-ventilated home filters and then circulates clean, fresh air to promote better respiratory health. Proper ventilation can reduce your exposure to Volatile Organic Compounds (VOCs), allergens, mold, carbon monoxide, and more. Use kitchen and bath exhaust fans when cooking and bathing. Do the toilet paper test to make sure the exhaust works properly. Change air filters regularly on heating/cooling units. For fireplaces, make sure the flue is clear and open when a fire is lit. Learn more about what is in your air. Of course you want to keep your home free of pests, but you may not realize how much harm bugs, rodents, and other pests can cause. Exposure to pests, such as mice and cockroaches has been linked to asthma in children. To control pests people often use pesticides which can cause further problems. The best way to control pests is to make your house less inviting. Seal cracks and crevices with copper mesh, expanding foam, or caulk. Eliminate sources of food and water by putting food in sealed containers and repairing leaks and dripping faucets. Use trash containers with sealable covers. Remove clutter, which reduces hiding places. Click here for more information on dust mites, roaches, bedbugs, and more resources on pests. Accidents happen, but some of them, like falls, fires, and poisonings, can be easily avoided with just a few simple steps. Falls are the leading cause of unintentional death in the home, followed by poisoning, choking, drowning and fire. The Centers for Disease Control estimate the costs associated with falls for people age 65 and over are more than $34 billion a year. Improving the safety of your home is important not only for older adults, but also for the entire family. Safety begins at home by reducing the likelihood of accidents and making your home a much healthier place to live. Use the Home Safety Checklist to review your home and see which areas can be made safer. Childproof Your Home using this room-by-room safety checklist. Store household cleaning products out of reach of pets and children. Click here to learn more about making your home safe. Many different contaminants may be found in your home, including radon, lead paint, asbestos, tobacco smoke, carbon monoxide, mercury, pesticides, and household chemicals. Below are tips for controlling contaminants in your home. Radon - The only way to know if you have this invisible, odorless gas is to test your home. Learn more at UGA Radon. Lead can be found in the soil, water and some consumer products. You can reduce lead dust in your home by adding a doormat, removing your shoes and keeping your home clean by damp mopping. Learn more on the UGA Lead Information page. Asbestos may be found in a wide range of building materials in older homes, including insulation, flooring, roofing and textured paint. The best thing to do is to leave it alone or hire a professional to remove it. For a list of asbestos contractors in Georgia, contact the Georgia Environmental Protection Division. Learn more about asbestos on the EPA website. Well Water needs to be tested for contaminants. Contact your Extension Office and test your water quality. Tobacco - Turn your home into a smoke-free zone. Carbon Monoxide - Maintain combustion equipment like heating systems. Mercury - Clean up broken compact fluorescent lights and go to Earth 911 to dispose of them. Hazardous Household Products - Store them out of reach of children and pets and learn how to properly dispose of items. Look-Alike Products - Leave products in original packaging and medications on the counter or in an accessible handbag. Your home is your biggest financial investment. Keeping your home maintained can protect you from moisture and pest problems, structural damage, and spending extra time and money on repairs that could have been prevented. Follow these simple steps to keep your home maintained. Check your home for "curb appeal" Use the UGA Home Maintenance Checklist. A green home is one that makes simple changes to conserve energy and natural resources. These changes will not only reduce your carbon footprint, but also save you money on energy and water, and create a healthier living space. Learn about going green by visiting UGA Greenway. Learn how to create a safe healthy child care environment.
{ "timestamp": "2019-04-22T18:21:55", "url": "https://www.fcs.uga.edu/extension/Healthy-Housing", "language": "en", "source": "c4" }
Snowflake Ruby Pendant Necklace In 14k White Gold 18 Inch Chain 0.67Ct. Snowflake Sapphire Pendant Necklace In 14k White Gold 18 Inch Chain 0.67Ct. Snowflake Diamond Pendant Necklace In 14k White Gold 18 Inch Chain 0.67Ct. This classic great looking diamond pendant is the perfect gift to give someone you love. �This sophisticated diamond pendant is crafted in quality metal 14k white & yellow gold, 18k white & yellow gold and platinum 950. �Hangs delicately from 14k gold and18k gold chain adding just the right sparkle to any outfit. Make your sweetheart feel very special every time she wears it. Perfect piece for a daily wear, and for the price you can't beat it at Javda ! Copyright © 2005 - 2017 Javda Inc.. All Rights Reserved.
{ "timestamp": "2019-04-23T20:15:41", "url": "https://www.javda.com/diamond-pendant~ord0~st10.html", "language": "en", "source": "c4" }
On Saturday 8th September, Mindful Mums staff and volunteers presented at the Perinatal Mental Health Conference held at the Princess Royal University Hospital. The event was attended by health professionals working in health and wellbeing during pregnancy, childbirth and the first year after birth. Karen Taylor from Mindful Mums shared how the service supports pregnant women and new women to look after themselves during a life changing period of their lives. Camilla, a Mindful Mum volunteer co-facilitating Mindful Mums Wellbeing groups, talked about her own experiences of pregnancy, childbirth, being a new mother and volunteering. She also talked about the importance of peer support for pregnant women and new mothers, and the space provided by Mindful Mums for women to share experiences, learn from and support each other. Perinatal professionals can refer pregnant women and new mothers living in the boroughs of Bromley or Lewisham, or women themselves can contact Mindful Mums themselves to book places on groups.
{ "timestamp": "2019-04-22T16:36:11", "url": "https://www.blgmind.org.uk/news/2018/09/mindful-mums-at-perinatal-mental-health-conference/", "language": "en", "source": "c4" }
HARRISBURG, Pa. — As part of its commitment to provide quality transit service to central Pennsylvania’s paratransit ridership, the Capital Area Transit (CAT) People with Disabilities (PWD) Advisory Committee will conduct a system wide survey of PWD transit riders in three counties, according to FOX43. The survey objectives are to assess rider experience with CAT and other transit services and to see if there are trends that suggest areas for improving rider experience and rider access to both fixed-route and paratransit services. The committee developed the survey with assistance from the Disability Advocacy Support Hub, a project of the Disabilities Rights Pennsylvania, through a grant from the PA Developmental Disabilities Council. For the full story, click here.
{ "timestamp": "2019-04-24T20:08:23", "url": "https://www.metro-magazine.com/accessibility/news/713965/pa-s-cat-to-survey-paratransit-users-to-improve-rider-access-experience", "language": "en", "source": "c4" }
61 How to make multiple divs display in one line but still retain width? 19 How do I do an XPath query on a DOMNode? 14 How to force truncate all tables(which are all innodb) in a database in MySQL? 11 Phantomjs - How to populate a form, submit and get the results? 10 How to merge multidimensional arrays while preserving keys? 9 jQuery - How to recursively loop over an object's nested properties?
{ "timestamp": "2019-04-18T19:24:57", "url": "https://expressionengine.stackexchange.com/users/636/arvinsim", "language": "en", "source": "c4" }
The article deals with the modern approaches to an initial and anti-relapse treatment of gastroesophageal reflux disease (GERD), based on the recommendations of the last two American consensus. According to these data, the main drugs for the treatment of GERD are proton pump inhibitors (PPIs), which are divided into the first- and second-generation drugs and can be used in standard doses, as well as in double- and half-doses. Second-generation drugs are more effective and safe as they less dependent on CYP2C19 polymorphism of. It is concluded that in most cases, the initial treatment should begin with the use of standard or double-doses of PPI, and supporting one — with standard or half-doses used for a variety of schemes — constant, intermittent or therapy «on demand». The best preparation for a long-term treatment of GERD, especially if it is necessary to take other drugs, is pantoprazole. Bekkers C.H., Touw D.J., Lamers C.B., Geus W.P. The effect of CYP2C19 polymorphism on the pharmacokinetics and acid-inhibitory effects of oral lansoprazole and omeprazole // Br. J. Clin. Pharmacol. — 2002. — 54(5). — 553. Donnellan C., Sharma N., Preston C., Moayyedi P. Medical treatments for the maintenance therapy of reflux oesophagitis and endoscopic negative reflux disease [Systematic Review] // Cochrane Database of Systematic Reviews. — 2005. — 3. — 3. Fitton A., Wiseman L. Pantoprazole. A review of its pharmacological properties and therapeutic use in acid-related disorders // Drugs. — 1996. — 51(3). — 460-482. Furuta T., Sugimoto M., Shirai N., Ishizaki T. CYP2C19 pharmacogenomics associated with therapy of Helicobacter pylori infection and gastro-esophageal reflux diseases with a proton pump inhibitor // Pharmacogenomics. — 2007. — 8. — 1199-1210. Gerson L.B., Triadafilopoulos G. Proton pump inhibitors and their drug interactions: an evidence-based approach // Eur. J. Gastroenterol. Hepatol. — 2001. — 13(5). — 611-616. Hagymási K., Müllner K., Herszényi L., Tulassay Z. Update on the pharmacogenomics of proton pump inhibitors // Pharmacogenomics. — 2011. — 12(6). — 873-888. Kahrilas P.J., Shaheen N.J., Vaezi M.F. et al. American Gastroenterological Association medical position statement on the management of gastroesophageal reflux disease // Gastroentero-logy. — 2008. — 135. — 1383-1391. Katz P.O., Gerson L.B., Vela M.F. Guidelines for the Diagnosis and Management of Gastroesophageal Reflux Disease // The American Journal of Gastroenterology. — March 2013. — Vol. 108. — Р. 308-328. Kromer W. Similarities and Differences in the Properties of Substituted Benzimidazoles: A Comparison detween Pantoprazole and Related Compounds // Digestion. — 1995. — 56. — 443-454. Li X.-Q., Andersson T.B., Ahlstrom M., Weidolf L. Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities // Drug. Metab. Dis. — 2004. — 32(8). — 821-827. McNamara D. Gastro-oesophageal reflux disease and ulcer disease in Europe // The Burden of Gastrointestinal Diseases in Europe. — 2004. — 31-36. Miner P.B. Jr, Katz P.O., Chen Y., Sostek M. Gastric acid control with esomeprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole: a five-way crossover study // Am. J. Gastroenterol. — 2003. — 98. — 2616-2620. Mullin J.M., Gabello M., Murray L.J. et al. Proton pump inhbitors: actions and reactions // Drug. Disc. Today. — 2009. — 14(13–14). — 647-660. Ogawa R., Echizen H. Drug-drug interaction profiles of proton pump inhibitors // Clin. Pharmacokinet. — 2010. — 49(8). — 509-533. Pace F., Tonini M., Pallotta S. et al. Systematic review: maintenance treatment of gastrooesophageal reflux disease with proton pump inhibitors taken ‘on-demand’ // Aliment Pharmacol. Ther. — 2007. — 26. — 195-204. Richter J. The refractory GERD patient // World Gastroenterol. News. — 2007. — Vol. 12. — 11-13. Sachs G., Shin J. Differential reversal of inhibition of gastric H/K-ATPase following pantoprazole or omeprazole administration // Am. J. Gzstroenterol. — 2001. — 96. — S71. — Abstr. 223. Steinijans V., Huber R., Hartmann M. et al. Lack of pantoprazole drug interactions in man: an updated review // Int. J. Clin. Pharmacol. Ther. — 1996. — 34(1 Suppl.). — S31-S50. Tanaka M., Ohkubo T., Otani K. et al. Stereoselective pharmacokinetics of pantoprazole, a proton pump inhibitor, in extensive and poor metabolizers of S-mephenytoin // Clin. Pharmacol. Ther. — 2001. — 69(3). — 108-113.
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