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Home » Medical
Barr wants to investigate origins of agencies 'spying' on Trump campaign
16 April, 2019, 10:41 | Author: Sherman Richardson
Barr, appearing before a Senate panel hearing, declared Wednesday he believes "spying did occur" on Trump's campaign, suggesting the origins of the Russian Federation probe might have been mishandled.
Although a judge signed the warrant for the surveillance after Page left the campaign, it was controversial because the spying was said to have been based on information provided by Christopher Steele, a former British intelligence agent, whose work was paid for by the Democrats.
Barr said he hasn't specifically studied the States Act himself, but the Justice Department is reviewing the legislation.
The investigation cleared him and his aides of collusion, making no determination on whether they had tried to obstruct justice.
'This was an attempted coup. "And we beat them, we beat them", BBC News quoted Donald Trump as saying.
"So the Mueller report, when they talk about obstruction we fight back". Barr responded by asking the congressman: "Do you think it's likely that we are gong to prevail?" "Because I knew how illegal this whole thing was, it was a scam". It was a scam. "Perpetuating conspiracy theories is beneath the office of the Attorney General".
"He's doing a great job, getting started on going back to the origins of exactly where this all started". He said that the letter may have been read to them, but they did not get a hard copy of it.
In a message to his fans, Bieber explained that he has to focus on his health before he can make his musical comeback. The interaction surely got fans' attention as one said, "I smell jealousy here".
"What is incredible here about Attorney General Barr is really his by the book manner, his ability to cut through the Democratic games, and also the willingness to get to the bottom of exactly how this Russian Federation probe came about and whether or not there was foul play here", he said on FOX Business' "Making Money with Charles Payne" Wednesday.
Barr told Congress on Tuesday that he is "reviewing the conduct of the investigation and trying to get my arms around all the aspects of the counterintelligence investigation that was conducted during the summer of 2016".
I assume that when Barr spoke of exploring whether the spying on the Trump campaign was "adequately predicated", he was referring at least in part to the reasons presented to the FISA court for authorizing electronic surveillance of Page. "But the question is whether it was predicated, adequately predicated", Barr said.
Barr said he doesn't have any specific evidence that the Federal Bureau of Investigation or other US intelligence agencies did anything wrong, but he does have concerns about how all of this went down. "I want to make sure there was no unauthorized surveillance".
Shaheen then questioned Barr if he believed the bureau spied on members of the Trump campaign.
President Trump and his conservative allies have repeatedly suggested the Obama administration planted a mole in his presidential campaign to undercut his candidacy.
Trump criticized the waste of almost $30 million that "haters" of his presidency spent on the investigation but noted that it still came up empty.
How BTS Became the K-Pop Band That Took Over the World
The music video, which features Halsey , has since received over 100 million views on the video platform. However, it has now been surpassed by the Bangtan boys with a massively huge margin.
Canada man disguised as delivery person shot woman with crossbow
Police believe the crossbow that was used was similar to one they presented at Monday's press conference (pictured). She was hit in the chest and suffered life-threatening injuries, but survived.
About 1 out of every 1,000 children who gets measles will develop encephalitis or swelling of the brain, according to the CDC . Most of the cases have been in NY , site of an outbreak among ultra-Orthodox Jews that started in the fall.
The episode topped the 16.1 million who saw the seventh-season premiere and the 16.9 million who watched that season's finale. If the show's final season can manage to top that, then " Game of Thrones " really will be going out on a high.
Sacramento had its most wins since going 44-38 in 2005-06 during coach Rick Adelman's final season. The other coach who is reportedly in the mix is former Cleveland Cavaliers head coach Tyronn Lue.
Wilson will report to Seahawks even without new deal
If the Seahawks can't lock up Wilson to a new deal, the franchise likely will use the franchise tag on the quarterback. Rodgers is back atop the quarterback pay scale after signing an extension past year that averages $33.5 million.
Mobile might start selling the Pixel 3 and Pixel 3a
Further evidence that this announcement might pertain to the Pixel 3a and Pixel 3a XL comes from 9to5Google's Stephen Hall. Furthermore, it's also said that the unannounced Pixel 3a and Pixel 3a XL are also going to be heading to the Un-Carrier.
Trump bucked decades of presidential tradition by declining to show voters his tax filings, both as a candidate and as president. But history would appear to be against him: Minnesota has not voted for a Republican for president since Richard Nixon in 1972.
Dog found swimming 136 miles from shore
They used a rope to pull the shivering dog to safety, Payalaw said, adding that the rescue mission took about 15 minutes. We looked for a way to help her and in the end, chose to use the rope to tie around her body to lift her up.
Chhetri said the plane skidded off the runway, hitting a helicopter belonging to Manang Air. It is particularly busy in April as the spring mountain climbing season begins.
He also spoke about building office products for the cloud-connected era, combined with advancements in 5G and AI. He shared an image on Twitter which consist of the text written in Mandarin along with the launch date.
Former head of Volkswagen could face 10 years in prison
Ilhan Omar: Muslim lawmaker sees rise in death threats after Trump tweet
Overdose deaths decrease for 1st time in 3 decades
Healthy Bodies in Mental Health; How Internal Med Treats Depression
DRC detects 1st Ebola case in eastern city of Goma
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Matthew Komar
Matthew Komar (°1990, Matawan, United States) is an artist who mainly works with film. By using popular themes such as sexuality, family structure and violence, Komar touches various overlapping themes and strategies. Several reoccurring subject matter can be recognised, such as the relation with popular culture and media, working with repetition, provocation and the investigation of the process of expectations.
His films often refers to pop and mass culture. Using written and drawn symbols, a world where light-heartedness rules and where rules are undermined is created. By parodying mass media by exaggerating certain formal aspects inherent to our contemporary society, he makes works that can be seen as self-portraits. Sometimes they appear idiosyncratic and quirky, at other times, they seem typical by-products of American superabundance and marketing.
His works are saturated with obviousness, mental inertia, clichés and bad jokes. They question the coerciveness that is derived from the more profound meaning and the superficial aesthetic appearance of an image. By rejecting an objective truth and global cultural narratives, he creates with daily, recognizable elements, an unprecedented situation in which the viewer is confronted with the conditioning of his own perception and has to reconsider his biased position.
His work urge us to renegotiate film as being part of a reactive or – at times – autistic medium, commenting on oppressing themes in our contemporary society.
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Tutorial: AKVIS Charcoal
Charcoal Sketch
Gallery of Works
Print Images in AKVIS Charcoal
In the standalone version of AKVIS Charcoal you can print the image.
Press the button to open the Print options.
Print Options in AKVIS Charcoal
Adjust the parameters appearing in the Settings Panel:
Choose a printer from the list of available devices, set the desired resolution, as well as the number of copies to print.
In the Orientation group, set the position of paper: Portrait (vertically) or Landscape (horizontally).
Click the Page Setup button to open a dialog box to choose the size of the paper and its orientation, as well as the print margins.
Press the Reset Margins button to return the page margins to the default size.
Change the size of the printed image adjusting the parameters Scale, Width, Height and Fit to Page. These parameters have no effect on the image itself, just on the print version. You can change the size of the printed image by entering any value in %, or by entering new values in Width and Height.
To adjust the size of the image to the paper size, select Fit to Page.
Move the image on the page with the mouse or align it using the arrow buttons.
You can activate Frame for the image and adjust its width and color.
Choose the Background Color by clicking on the color plate.
In the Page tab, you can adjust printing of the multiple copies of the image on a single sheet.
Copies per Page. It lets you specify the number of copies of the image on one page.
Horizontally and Vertically. These parameters indicate the number of rows and columns for the copies of the image on the page.
Spacing. The parameter sets the margins between the copies of the image.
In the Poster tab, it's possible to customize printing of the image on multiple pages for the subsequent junction into a large picture.
Pages. If the check-box is enabled, you can specify the maximum number of the pages in which the image will be divided. The image scale will be adjusted to fit this number of the sheets. If the check-box is disabled, the program will automatically select the optimal number of the pages in accordance with the actual size of the image (scale = 100%).
Glue Margins. If the check-box is enabled, you can adjust the width of the padding for bonding sheets. Margins will be added to the right and to the bottom of each part.
Lines of Cut. Activate the check-box to display the cut marks in the margins.
Show Numbers. With the enabled check-box, a sequence number of each part, by a column and a row, will be printed in the margins.
To print the image with the chosen parameters, press the Print button.
To cancel and close the printing options click on Cancel.
Click the Properties... button to open a system dialog box that enables you to access the advanced settings and send the document to print.
Charcoal v. 3.2 - Free 10-day Trial
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This is a Roleplaying Site » Teen+ » Roleplay » One on One and Private » One on One » Jovec and Pierrot's One on Ones » Calling Death: Rose
Calling Death: Rose
Go to page : 1, 2, 3, 4, 5, 6, 7, 8
51 Re: Calling Death: Rose on Wed Aug 27, 2014 2:59 pm
♙ K i n s e y & K r o n o s
"Probably asleep in a tree outside or something. Who knows with him?" said Kronos. "Though you can teleport, he can travel at the speed of light, it'll be a true game of cat and mouse."
"Pfft. He can't catch me." Pearle said, although he was preeetty sure that Disparity could.
"Go challenge him then. He needs the exercise."
"Ho? You're saying he's fat and out of shape?"
"No, I'm saying he's a skinny, lazy bum who needs to do something."
"Aww." He folded his arms. "I liked the idea of him being fat."
"That man will never get fat, his metabolism is insane."
"Challenge accepted."
"Then off with you," said Kronos. "Your sister is making me do laundry today."
"Okay~! See ya, Pops!" He then started off to find Disparity. Aoi giggled. "Sounds like he's in love with this Elaina and yet denying it."
Kronos left.
"I didn't follow any of that," said Kinsey with a sigh.
♙ D i s p a r i t y
Disparity was eating chocolate-covered cherries in the garden.
Aoi giggled. "That's fine, sorry you had to be confused. You'll understand in time."
"Old man!" Pearle said, approaching once he found him.
63 Re: Calling Death: Rose on Wed Aug 27, 2014 10:26 pm
♙ K i n s e y
"So.. He was their father?" she asked.
"Hey! If it isn't the snot-nosed brat!" he replied in greeting.
"The man that's doing the laundry? He is the triplets' father. And the triplets are step-brothers to the woman that lives here. She looks just like that guy. They share the same father but different mothers. I'm unsure about the woman's mother but my husband did tell me that his mother was a queen. Sorry if it sounds confusing, I've only married into this family recently."
"Ha! Your insults don't affect me!" He noticed the cherry. "Hey, if you continue eating things like that you'll get diabetes, Mr. I'm-Ancient."
"It's quite alright. Though if they share a parent, they are half-siblings," said Kinsey with a smile. "Who else lives here?"
"It's got fruit," he said, humming. He offered them to Pearle.
66 Re: Calling Death: Rose on Thu Aug 28, 2014 12:06 am
"Oh, right, half." she said, laughing. "Then there's Disparity, who's been here far longer than I have. He helped raise the triplets I think so they've grown accustomed to calling him 'uncle'. Then there's Sininen, Aureliana's brother. Aureliana and Sininen are half dragon and half angel I think. Or have a little bit of human...? Whatever but their father was a full dragon." She hummed, "Yui used to live here too, but after her divorce with Platinume she left with Mei Long and is raising her own child with him now." She had a finger up for every person she named that either lived or used to live in the house. "Elaina comes and visits every once in a while, same with the Council bastards... Ah! Alec! I heard there used to be a guy named Alec here but he ended up disappearing. Same with Cornelius. Both are full dragons. Platinume lives here along with his daughter. Aaaand I think that's about it." She hummed then she concluded her train of thought after keeping track of who lived there and used to live there. "So basically, Platinume, Delilah, Disparity, Kronos, Aureliana, her mother and brother live here. Sorry, I had to keep track of all of that so I won't say the wrong names."
Pearle took some, "So where'dja get these?" he asked, "A new boyfriend or something?"
"It's quite alright," said Kinsey with a laugh. "So, you and your husband don't live here?"
"I wish," Disparity said. "But, nah. I got them at this really cool chocolate shop."
68 Re: Calling Death: Rose on Thu Aug 28, 2014 1:05 am
"Oh no. We live by the elementary school nearby. My husband is a teacher there."
"Have you ever found that Alec guy?"
"Oh, I see. How often do you two come by?"
"...No," he said, a slight pain in his eyes. "Not yet... I think it's about time I give up.."
"Very often actually." she said.
"Do you think he's...dead? He is a dragon after all, and you know how much humans hate dragons..."
"That's good. I'm glad to see someone so close to their family."
"Could be...," he said grimly. "I don't know."
Aoi smiled, "Were you close to family?"
"I say don't stop searching until you find his whereabouts." Pearle said. "If Elaina went missing I wouldn't have stopped until I know that she's okay. Wouldn't you do that for Alec if you loved him enough?"
"Until I moved to the city, yes."
"No," said Disparity. "Though if this Elaina goes missing, you should check your father's room first. Especially if she's attractive and/or has sex appeal."
"Oh? You lived elsewhere? Where'd you used to live?" she asked.
Pearle bit the bottom of his lip to prevent the thought of Elaina being in his father's room. "How come Pops taking her has to be mentioned every time I mention Elaina? And what about Dyemond's wife? She has sex appeal and is attractive. And what about Platinume's ex? Nothing happened to her! So why Elaina? Maybe I just want her mine and only mine! It's not like I'm ready to marry her yet or anything but hearing that just makes me want to push the relationship further just so that she's secure to be my woman!" He huffed, folding his arms and looking to the side, red from either jealousy or anger.
"Out in a forest in a small wooden cabin."
"You know your father and I only taunt you. I do it because it's my hobby. Your father does it because he doesn't want you to end up like Platinume."
76 Re: Calling Death: Rose
» Death Breather....
» Onyx's death
» Scarlett Death
» Death wish comes for pleasure stallions
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2018 Season Program
Volleyball Season Preview: Amherst Returns Talent, Depth for 2017
SEASON OUTLOOK
Capturing the program's fourth consecutive No. 3 seed and returning to the NESCAC Championship for the 18th-straight season last fall, the 2017 Amherst College volleyball team starts its bid to build on the accomplishments of last season and return to the league finals for the first time since 2008 on Wednesday, Sept. 6 with a 7 p.m. non-conference match at Springfield.
Led by head coach Sue Everden, the Mammoths remain positioned for a successful year on the court, boasting a squad that features 11 returners (four seniors, two juniors, five sophomores) from last year's team that finished with a 17-9 overall ledger and a 7-3 mark in NESCAC play.
MEET THE PLAYERS
Welcoming back an abundance of skill at outside hitter, Lauren Reppert '19 and Emily Kolsky '20 take to the floor after appearing in all 26 matches for Amherst last season. With 143.5 total points, Kolsky was one of the Mammoths top point-getters and added 125 kills and 344 attacks, while Reppert cataloged 94 kills, 314 attacks and 44 blocks.
Headlining the setter position are Charlotte Duran '20 and Adelaide Shunk '20, with both student-athletes poised to run the floor for the Mammoths. Duran enjoyed a productive debut season, tallying 152 digs and a team-high 429 assists, while Shunk recorded a 2.09 assists per set average.
At the net, Marialexa Natsis '18, Annika Reczek '18 and Claire Dennis '20 are primed to be difference makers. Natsis was stellar for Amherst in her junior campaign, leading the squad in total blocks with 77 and notching 251.0 total points. With 197 kills and 511 attacks in 2016, the Los Angeles, Calif. native leads all returners in both categories, while Reczek and Dennis look to build on their 70 blocks (T-7 NESACAC) and 38 kills, respectively, from a year ago.
Led by Hayes Honea '19, the Mammoths return depth and experience to the transition game. More than doubling her dig total from her rookie season, Honea amassed 492 digs last fall (5.86 d/s) to lead Amherst and rank third overall in the NESCAC in addition to posting 49 assists and a team-high 24 services aces.
Asha Walker '18 also looks to build on a solid 2016, with Walker returning to the court after tying for second on the team in service aces with 22 and registering a noteworthy 167 digs last season. Kate Antion '18 and Candace Chung '20 round out the Mammoths' veteran defensive specialists, with the duo expected to make significant contributions in the backcourt.
Amherst begins 2017 with five away matches, first traveling to Springfield on Wednesday, Sept. 6 for its season opener beginning at 7 p.m. The Mammoths then square off against Western New England (9/8) before taking on Emerson and Colby in a double-header on Sept. 9 at 11 a.m. and 1 p.m., respectively. Following a midweek non-conference matchup against Endicott (9/ 13), Amherst returns to the Pioneer Valley and welcomes Middlebury to LeFrak Gymnasium on Sept. 15 for its lone home contest of September starting at 8 p.m.
The Mammoths close out the first month of the season with nine road matches, battling Saint Joseph's and Regis (9/16) in Weston, Mass. before traveling to Westfield State (9/19) and Trinity (9/22). A non-league tri-match with Husson and host Colby-Sawyer is slated for Sept. 23 and is followed by a NESCAC bout against Connecticut College on Sept. 29. Amherst travels to Little III rival Wesleyan a day later, hitting the court against the Cardinals at 11 a.m. and non-league foe Stevens at 1 p.m.
October kicks off with back-to-back NESCAC opponents at home, as Tufts and Bowdoin take on the Mammoths on Friday and Saturday, Oct. 6 and 7, respectively. Amherst then travels to Clark University (10/11), Hamilton (10/13) and archrival Williams (10/14) before closing out the regular season with five consecutive matches at LeFrak Gymnasium.
After hosting Wellesley on Oct.20, the Mammoths are set to play Coast Guard and WPI in their annual Hall of Fame Invitational tournament on Saturday, Oct. 21. Amherst ends the regular season with two league matches, squaring off against Bates on Oct. 27 at 8 p.m. and Colby on Oct. 28 at 2 p.m.
Not yet a member of the Friends of Amherst Women's Volleyball for the 2017-18 year? Become a first-time member of or renew your membership in the FAA and support Coach Everden and the women's volleyball program. Make a gift ahead of the team's season opener at Springfield on Wednesday, September 6 beginning at 7 p.m. Go Mammoths!
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You are at:Home»Afghanistan»Rules of engagement again questioned on Capitol Hill
Rules of engagement again questioned on Capitol Hill
By Dan Lamothe on June 29, 2010 Afghanistan, Capitol Hill, Infantry
Cpl. James Kirkpatrick, of Kilo Company, 3rd Battalion, 6th Marines, makes a long leap across a canal east of Marjah, Afghanistan while on patrol May 24. Kirkpatrick's squad was later attacked during that same patrol in a coordinated attack. (Thomas Brown/Staff)
Rep. Walter Jones is back at it.
The Republican congressman with Camp Lejeune, N.C., in his backyard has again picked up the drumbeat calling for a congressional review of the rules of engagement used by the U.S. military in Afghanistan.
In a letter released Friday, Jones again asked House Armed Services Committee Ike Skelton, D.-Mo., and ranking member Howard “Buck” McKeon, R.-Calif., to hold a “classified hearing” in which military leadership explains the rules under which rank-and-file troops conduct operations outside the wire. The letter is also signed by Reps. Jeff Miller, R.-Fla., and Doug Lamborn, R.-Colo.
“As you are fully aware, recent media reports have increasingly raised the issue of the current Rules of Engagement (ROE) and Tactical Directives in Afghanistan,” the letter said. “We feel it is imperative that the Full Committee hold a classified hearing on this issue as soon as possible in order for Members to better understand whether the current Rules of Engagement and Tactical Directives are the best policy for our servicemembers fighting bravely in Afghanistan.”
It isn’t the first time Jones has called for a review of ROE, the classified guidelines under which Marines, soldiers and other U.S. service members fight. As Marine Corps Times has covered ad nauseum, they’ve been criticized repeatedly in recent months, including in an October cover story in our magazine.
In previous interviews, House Armed Services Committee staffers have said an open hearing on ROE would not be possible due to the classified nature of the discussion. A classified briefing before the whole committee is unlikely unless more members call for it, a committee staff member speaking on background told me in October.
An interesting footnote to the whole discussion: Jones, Miller and Lamborn use comments in the recent blockbuster Rolling Stone article that led to the demise of Gen. Stanley McChrystal to bolster their argument. They point out that a Special Forces operator who spent years in Iraq and Afghanistan told Rolling Stone that “every real soldier will tell you the same thing” about the ROE — that it puts lives in danger.
Coming off my recent embed with 3rd Battalion, 6th Marines, in Marjah, it came as no surprise to me that Rolling Stone was able to find troops frustrated by the ROE defined by McChrystal. For example, Marines I went on patrol with in Afghanistan expressed dread over dealing with spotters, who observe Marines on patrol and drop back as they advance, only to disappear completely when nearby insurgents working in coordination with the spotters open fire.
Since the spotters carry no weapons, Marines say they are not allowed to fire on them, even though their involvement in a pending attack is obvious. As one corpsman said before we came under fire in May, it always starts with “one guy pointing.”
In a telephone interview, Jones told me this afternoon that he continues to hear ROE concerns from “moms and dads” in his district regularly, and believes the whole armed services committee needs to hear about the restrictions U.S. troops face.
“To me, it just sounds like a chaotic situation,” he said. “If we’re going to send them over there and keep them there, for God’s sakes, they need to be able to defend themselves.”
Johnny on June 30, 2010 8:33 am
I’m just a civilian but I think the ROE is nonsense it seems like until one of your soldiers are killed then you shoot back
joyc on July 2, 2010 9:54 am
ROE are prohibitive to the detriment of our troops lives; the troops who have put their lives on the line for what is suppose to be a worthy cause.
Duane on July 2, 2010 5:25 pm
In war ROE will get you killed or brought upon charges.
Our ROE should be the same as the person we are fighting,
it is the only way to win. If we are not there to win, then we should get the hell out of there. God Bless our Troops.
Barb on September 23, 2010 8:53 pm
These U.N. rules as complicit by our neutered military leadership including the current and past President, are KILLING and imprisoning our troops!!
We believe they are outrageously stupid, giving the upper hand to the enemy!
Who the heck created these? Desk jockey bureaucrats who have never seen combat!
The Leavenworth 10 are WRONGLY incarcerated because they chose to PROTECT AMERICAN LIVES than protecting the enemy!
http://www.facebook.com/#!/pages/ROE-Rules-of-Engagement-US-Military/133982856628453?ref=ts
Sandra on September 23, 2010 8:58 pm
LISTEN UP CONGRESS AND PRESIDENT OBAMA!
Spotters are ENEMIES, not ‘civilians’ and should be dealt with accordingly!
Stephanie Gibson on September 23, 2010 10:01 pm
I think it is disgusting how the government does not support our troops. With the ROE they have, our president and the whole bunch in congress might as well be holding a gun at the heads of our troops themselves. Those of us who have children in Iraq and Afghanistan take this very personal. Send your children to war, and then tie their hands behind their backs.
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Use The “Archives” feature on the News & Events Page HERE to access all “Recent Events’.
The entries below are taken from BeCA’s Original “Website” page and are now ‘stored’ below for historical reasons.
Welcome To The New member Of The Family: (10/2/2010)
Visitors to Lake Bellvista have been delighted to see the Lake’s resident swan family has a new addition! This young addition has been spotted making itself at home under the careful eye of Mum and Dad! Some residents think there may have been more cygnets in this hatching but perhaps there were lost in the recent heavy downpour which may have caused the lake water level to rise and possibly wash some of this year’s brood away.
Sometimes nature can be very cruel!
Added Feb 12th: The two adult swans were swimming around without the young one this morning, we wonder what has happened and fear the worst.
Traffic Bankup At Unity College Pick-up Time: (2/2/2010)
These photos were taken at 3 pm on Tuesday February 2nd at the roundabout connecting Bellvista Blvd and Dumbarton Drive. The photo above left shows traffic banked up from the roundabout heading north towards Caloundra Rd. The other photo above right shows the view looking south across the roundabout back towards the school.
Current school enrolment is just over 900 students. Unity College has been designed to accommodate 1400 students.
What if ……..
You needed to get to an important appointment in Caloundra.
There was a serious medical emergency and an ambulance wanted to get the patient up Bellvista Blvd to hospital.
There was a fire and Bellvista residents had been advised to evacuate the estate.
The answer is, hope it doesn’t happen between 2:30 and 3:30 pm on a school day!
Back To School 2010 (26/1/2010)
Today is the day before school begins for some Unity College students and the welcome mat is out already.
New buildings are being finalized and all is ready to go.
This new Phys Ed assembly area was getting the final touches this morning when the photo (lower right) was taken.
You can access the Unity College website here to catch up with all the latest news.
A Sunshine Coast Regional Council Service Request was entered on Sunday to arrange for the removal of the dumped van beside the Rugby Fields belonging to Unity College. The abandoned vehicle has now been removed.
An online link to a Sunshine Coast Regional Council Service Request form can be found on the “Handy Links” tab or just click HERE.
Building Developments Continue On Our Estate. (20/1/2010)
Several Medium Density Developments on our estate are progressing well. The project pictured above left on the junction of Lomond Cres and Balmoral Blvd (near the old land Sales Office and the Lake) is well underway as can be seen in the photo. The other project (pictured above right) being built on land on the corner of Tanna St and Rawson St is also coming along quite well. A third development adjacent to the site of the new shopping complex has begun as well.
One of the BeCA Committee members reports she has heard a contract has recently been signed for an IGA Supermarket to be included in the Shopping Complex planned for the corner of Rawson St and Lomond Cres.
Happy New Year! (12/1/2010)
Though not on the Bellvista Estate, there is a lot of work on cleaning out “Duckponds” as seen in the photo lower left. Duckponds is across the road from the Tourist Information Centre in Caloundra Rd.
And there is certainly less bird life on the Bellvista Lake right now. This may be caused by the new notices asking people not to feed the birds. This should ensure our lake remains cleaner and healthier. The cygnets have now gone as well. The parents swans remain but the youngsters have been sent on their way to make a new life for themselves.
Paul Harrison (Convenor of the Landscaping Sub Committee) reports the majority of Council workers were due to report back to work on Monday January 11th. The heavily overgrown park in Shannon St was mowed recently and we expect other parks to be mowed as January continues. Rains over Christmas has meant the grass in parks has grown!
Paul is forwarding an update request to Council regarding the Telstra Pit Cover (See Below) which still hasn’t been replaced.
Sewerage Works Continue, (9/12/2009)
Sewerage works are continuing in the park at the end of Huntley Place and Lindesay Street. A tall gum tree has been removed when it was discovered it was badly infested with termites. Workmen worked over night to extend the works across Bellvista Blvd. Now the work is extending on the eastern side of Bellvista Blvd. Restoration works for the park will be completed shortly.
Creek Cleanup (7/12/2009)
This photo was taken from the bridge in Huntley Place near the roundabout intersection with Dumbarton Drive. The creek behind the Medium Density Site in Lindsey St has now been cleared. Several snakes have been seen in the Medium Density Site recently and this tidying up of the creek should keep those unwanted visitors away and residents safer.
Bellvi sta Lake Tidy Up (3/12/2009)
This hefty looking machine recently was put to work in clearing some unwanted growth from the lower Bellvista Lake. A closer inspection of the top lake showed it was fine and that no clearing was required. BeCA spoke with an SCRC representative onsite who reported she was very happy with the condition of the lake.
She went on to say that it appears residents are taking note of the No Feeding signs now around the lake as the number of birds has not increased and birds no longer follow or swim up to people as they approach the water. She seemed extremely pleased with the community response on this issue.
Bellvista Retail Development (3/12/2009)
BeCA recently received information from the developer of the new Bellvista Retail Development on the corner of Lomond Cres and Rawson St, Mal Pratt and Associates. Power has now been connected to the site in anticipation that building is about to commence.
They have leased a pharmacy, family medical centre and bakery café at this stage and have an appointment booked to speak with a hairdresser early next week.
The developer wishes the Bellvista Community Association a wonderful Christmas and New Year and look forward to more contact with BeCA in 2010.
No Standing Signs
GriffinCres has been a popular dropping off and collecting point used by parents of students attending Unity College.
Some days this has caused some angst between property owners and parents collecting their children. The school has gone to great lengths to ensure appropriate points are used by parents to safely drop students off. The new Staff Car Park frees even more spaces for parents dropping off or collecting children within the school property.
After much discussion between SCRC and Griffen Cres land owners No Standing between 8am to 9 am and 2:30pm to 3:30pm signs have now been erected.
Tidying Up Commences
SCRC (Sunshine Coast regional Council) recently began its promised work on cleaning out the drain running between Huntley Place and Maroon Crt.
SCRC has been doing a lot if tidying up around our estate including the main roundabout at Bellvista Blvd and Dumbarton Drive. Line of sight view is much improved since the work was completed.
It is good to see the picnic table in the main park has been replaced too following vandal damage.
Unity College School Crossing Opened
The Unity College School Crossing volunteer parents went through their final ‘on the job’ training today Oct 13th. The ‘Children Crossing’ flags were out and the lollypop “Stop” sign was in action.
Volunteers were shown the procedures they were to follow to ensure children were able to safely cross Lomond Cres. This service will become even more appreciated by Bellvista parents when the new shopping complex is in operation further along Lomond Cres in mid 2010.
Thanks to all the volunteers, without you this valuable service would not be possible.
Recent Bellvista Community Events:
Nominations For BeCA Committee:
The following residents were elected at the AGM conducted at the Bellvista Estate Sales Office at 6:45 pm on Monday September 7th, 2009. A special welcome aboard to Paul Harrison.Many deep thanks to the two original members of BeCA who did not forward nomination forms. John Lehman is hopeful that his immediate family health concerns can be overcome and that he can return to BeCA involvement. Roger Tedmanson is currently touring Australia and it was not possible to contact him to ensure his nomination was received. BeCA wishes to express its deepest thanks to both retiring members for their contribution to BeCA.The Committee for 2009-10 is:President: Phil Williams Secretary: Tony Mohr Treasurer Kerry Baxter Committee: Matt Inglis Les Thomas Colin Murphy Bern Johnson Paul Harrison
Community and Aviation Industry Forum August 2009:
BeCa was invited to send a representative along to a forum of interested local organisations and stake holders at the local Council Offices to discuss plans for the future development of the Caloundra Airport. Minutes from the meeting are available from the links below. There are also links to a ‘presentation’ delivered at the forum as well as another link to the forum’s Terms Of Reference. Bern Johnson attended representing our Association. Right Click on the link below and select “Save Link”.Download the Minutes HEREDownload the Presentation HEREDownload the Terms of Reference HERE
Here are some excerpts from the Minutes:
Replacement Aerodrome StudyExpecting a report from the State Government within the next 6 weeks to address the replacement of the aerodrome. Seeking a commitment from the State Government to fund replacement. In response to Caloundra Transit Orientated Community (TOC), relocation of businesses and employees needs to be addressed as a matter of priority. Cr Grosskreutz raised the two proposed sites of Johnson Road and the SEQ Regional Plan industrial designated area in Donnybrook with potential environmental, employment and amenity issues. Peter Pallot agreed that there would be concerns with the impact on surrounding areas. Peter Bryant asked if a new site was announced tomorrow, what would the required timeline be? Peter Pallot advised that 3 years would be an optimistic timeline. 1 year for Environmental Impact Statement (EIS) & design, 1 year for infrastructure such as roads, sewerage, power, etc, and 1 year for the building of the airport, and would require State Government support. Peter Ryan asked if it was a certainty that the Caloundra Aerodrome would close before the replacement one was opened. Peter Pallot advised that there is a commitment from the State Government for the siting of the replacement of the aerodrome but no funding commitment. Cr Grosskreutz stated that to her knowledge discussions have been occurring since 1998 in relation to the Caloundra Aerodrome. Peter Bryant stated that the Caloundra City Ratepayers and Residents Association support Caloundra TOC but have concerns there will be no replacement of the Caloundra Aerodrome. Warren Wiley asked in the event that the Caloundra Aerodrome is not replaced, can the Caloundra Aerodrome businesses merge or relocated to the Sunshine Coast Airport? Peter Pallot stated that this option is constrained by land holding issues (i.e. hanger space). However, Sunshine Coast Airport was exploring options. Peter Bryant stated that Ken Stevenson’s (formerly editor of the Caloundra City News) opinion was that the majority of economic benefit to the Caloundra region is from the helicopter industry. Can the aerodrome be limited to helicopter usage only? Cr Grosskreutz advised that the current Caloundra TOC doesn’t allow this. If such a decision was made, CAMCOS would have to be revisited. Cheryl Tillman advised there would be proximity issues with the helicopters near such transit facilities.Round table discussion was encouraged to put forward any community issues that come to mind. Cr Grosskretuz stated there were only short terms issues such as residents and appear to have been resolved.Bern Johnson advised she has noticed a significant improvement in the number of complaints regarding noise over the last few months. Complaints are down by at least half. However, during a recent meeting at the Golden Beach Bowls Club she did notice the noise to be an issue at this location.Cheryl Tillman advised that they are the only helicopter operators at the Caloundra Aerodrome. However, other helicopter training organisations can fly within an approximate 3 hour radius of their own base. So noise issues can often be other operators flying near Caloundra Aerodrome but are not necessarily using or based at the aerodrome. Peter Pallot advised that a similar problem was occurring at the Sunshine Coast Airport where helicopter operators not based at the airport can still use the airport’s facilities. This was overcome by increasing charges for usage after 10:00pm. Cheryl Tillman advised that the Caloundra Aerodrome is often used for maintenance and the arrival and departure of these aircrafts can sometimes disturb surrounding neighbours. Bern Johnson thanked Peter Pallot and Cheryl Tillman for the information and advised she’ll update the BECA blog which isaccessed regularly by residents. Cr Grosskreutz stated that noise complaints over the last few months have significantly improved in her electorate. Danny Eatock advised Caloundra helipad construction is due to begin in the next 2 weeks. Peter Pallot advised that a website for the Caloundra Aerodrome is under construction and will be accessible via www.caloundraairport.com.au. It will be a sub-site of the Sunshine Coast Airport’s website (www.sunshinecoastairport.com.au) and will provide information such as:
Information of CACA Forum
Aerodrome businesses information
Fly Neighbourly Agreement
Warren Wiley asked what was the critical timing for a decision to be made for the replacement aerodrome? Peter Pallot advised there is a window of opportunity of approximately 18 months to plan and secure funding for the new aerodrome. Cheryl Tillman advised the Sunshine Coast Aviation Group (which she is President of and also involves Peter Pallot) are trying to make representations to the State Government for such a commitment. Peter Ryan put forward that the aerodrome doesn’t necessarily have to cease operating after 2014. Gary Castle advised that aerodrome businesses continuing under a ‘periodic’ or annual lease past 2014 is not ideal. Peter Ryan asked what would happen if the Council decided to leave the Caloundra Aerodrome where it is? Cr Grosskreutz advised that the State Government most likely wouldn’t be concerned. However, then the Caloundra TOC would need to be revisited.
Caloundra South Proposal
In August BeCa was invited to attend a briefing at the Caloundra Council Offices on the “Caloundra South” proposal.The meeting was attended by 6 people, 3 SCRC representatives, 2 from BeCA and one from Golden Beach Progress Association.Here is the link to the Sunshine Coast regional Council page on the Caloundra South Proposal:
http://www.sunshinecoast.qld.gov.au/sitePage.cfm?code=caloundra-south&pv=1
Copies of the Caloundra South Position Paper and maps can be downloaded from the links below:
Caloundra South Position Paper [PDF 1.3MB]
Map 1.1 Structure Plan Area [PDF 1.4MB]
Map 1.2 Surrounding Land Uses [PDF 1.3MB]
Map 1.3(a) Significant Biophysical Constraints (Flooding) [PDF 1.6MB]
Map 1.3(b) Significant Biophysical Constraints (Ecologically Important Areas) [PDF 1.7MB]
Map 2.1 Caloundra South Preliminary Land Use Concept Map [PDF 1.3MB]
These maps (downloaded from the above links) show the area for development, the flood levels, the environmentally sensitive areas and the proposed development areas. There is also a lengthy ‘Fact Sheet” and a feedback form. During the briefing some time was spent going through the flood and environmental maps. Flood and environmental concerns means 40% of the proposed area is unsuitable for development.It will be completed by 2050.
The 2 pink areas just to the south of Bellvista (yellow arrow) are earmarked for development by Stockland for a further 500 dwellings in the near future. Throughout much of the development area (marked in pink), building heights can be between 8.5m and 13.5m.The state government has recently flagged another area to the south of this proposal for further future development. SCRC is opposed to this. It believes this current proposal satisfactorily meets the government’s requirement to house 50,000 residents by 2050.
cal_sthmap2_1.pdf (above) shows the plan for 2050. This development is planned to accommodate a further 50,000 people, the size of the previous Noosa Council area. Note its proximity to Industrial areas (seen more clearly on the downloadable maps). It is expected that the industrial areas and the shopping complexes will provide employment for 10,000 people.The new town centres are shown as blue circles. The town centre to the south of Bellvista (the smaller light blue circle) would be a shopping area similar in size to Currimundi Markets. The larger dark blue circle would be a major shopping centre. The blue line represents the proposed rail link. Two major roads will connect Nicklin Way (south of the proposed rail line) and the new road (Sunshine Coast Motorway) at the roundabout near Corbould Park race course.There will be a link road between Bellvista and the smaller shopping complex to the south. However this road is designed as a connection road, not a thoroughfare for traffic heading to Brisbane from the Sunshine Coast.We raised the concerns our community has of Bellvista Blvd and construction traffic when the two new areas are to be developed. Duplication was seen by us as a ‘must do’. SCRC informed us there will be a traffic count trigger point when this would happen. Our concern was resident safety prior to the trigger points being reached. The traffic problems created between the school traffic as well as construction vehicles using Bellvista Blvd between the hours of school arrival and dismissal times was mentioned.The SCRC mentioned that the roundabout (Bellvista Blvd and Caloundra Rd) would need to be reconfigured sometime as it was not working effectively.One of the SCRC representatives there was Ron Piper, a former Lensworth employee. When talking about the future of the Land Sales Office it was his impression that the building was to be handed over to the then Caloundra Council as a part of negotiations between Lensworth and the Council. He was quite surprised to hear it was still the subject of negotiation.Ron Piper will make a presentation of the Caloundra South Proposal at the BeCA AGM on Monday September 7th at the Land Sales Office commencing at 6:45pm.
BeCA Meeting With Mark McArdle:
In July 2009, BeCA Secretary Tony Mohr met with our local Member of Parliament Mark McArdle to discuss issues relevant to residents and landowners of the Bellvista Estate.
Tony’s report appears below:
Access to Bellvista (Bellvista Bvd.)
Mark agreed that access to Bellvista is restricted due to Bellvista Blvd. being only single road in and out. He also agreed that this is unlikely to change until Caloundra Downs was due for construction. Mark offered to write to Stocklands on our behalf and try to ascertain when this was likely to happen. He was going to suggest to Stocklands they address our AGM in September.
School crossing
Mark agreed that the crossing was essential and would raise the matter with Anna Grosskreutz at a meeting scheduled on July 2nd.
Retail Complex
Mark had no more news on this issue other then what is known now. He did say he was opposed to poker machines going into the Tavern and made that known on the Community impact statement. He agreed the retail complex must go ahead regardless of the outcome of the application for a licence by the tavern.
Mark stated that the airport was a complex issue and he would write to our Association with all the information he had at hand. He did state he would oppose any attempt to move the airport if the jobs at the airport were lost. I will publish the letter as soon as it arrives. We wait with interest.
Mark encouraged the formation of neighbourhood watch in the Bellvista area. His office will assist us where it can. They will produce the flyers we need to advertise the community meeting required to form the steering committee.
Stocklands sales office
Mark would raise the subject with Anna Grosskreutz at their meeting in July and do what he could to see the office is retained as a community asset.
I invited Mark to our AGM however he will be in Sydney at the time and will be unable to attend.
Tony Mohr
Secretary BeCA.
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WGN #19: Leage of Legends most played PC game and Diablo 3 RMAH commodity auctions
posted 11 Jul 2012, 10:37 by Wipus Frequentus [ updated 11 Jul 2012, 10:39 ]
Today we have news about a couple of games, but also some new features for the Wipus community.
As of today the Diablo 3 Real Money Auction House is almost fully functional. With the release of patch 1.0.3b it is now possible to sell dyes, gems, tomes, plans, designs and crafting materials for euro's.
Bioware announced the prevention of creating characters on certain origin servers. They also informed us of the fact that any remaining characters on those origin servers will be automatically transferred later this summer. This basically comes town to server merges, except they don't call it that.
League of Legends is a very popular game, except none of us could have imagined that it's the most played PC game in the world according to Xfire. In one year time more than 1.3 billion hours of gameplay were logged by Xfire, compare that to the "measly" 600 million by World of Warcraft. Even though this is not a 100% reliable measure it still is a significant accomplishment for Riot Games. On another note, today they also give us a sneak peak at a new champion called "Zyra". This is one thorny lady.
If you've registered for the Planetside 2 beta, you will be pleased to know that it will start within the next month. Unfortunately they will give priority to active planetside 1 players. Maybe some of us will get lucky though.
If you are enjoying reading these snippets of news on a daily basis, why not have a look at out Google+ page and join our circle so you know instantly when another article is available. You can also subscribe to our RSS feed and get your fix delivered instantly to your Feed Reader.
Tags: Wipus Gaming News, SWTOR, Diablo 3, League of Legends, PlanetSide 2
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Sarah Ferguson will attempt first world-record swim around perimeter of Easter Island
Sarah Ferguson will attempt first world-record swim around perimeter of Easter Island:
February 11, 2019 – MALIBU, Calif., U.S. – Plastic Oceans International and Breathe Conservation, two global nonprofit organizations dedicated to solving the plastic pollution problem, today announced Swim Against Plastic: Easter Island, a campaign to raise awareness about plastic pollution with a world-record swim, education and beach cleanups on Easter Island in March.
Sarah Ferguson, a former national swimmer for South Africa and founder of Breathe Conservation, will attempt to set a world record to become the first person ever to swim the entire perimeter of Easter Island. Her journey will cover more than 40 miles (65 kilometers) through cold water and dangerous currents, and the swim is estimated to take up to 24 hours to complete.
“This is a huge challenge, but my passion for ocean protection and rehabilitation is a strong driving force that fuels this dream,” said Sarah Ferguson, founder of Breathe Conservation. “It is our responsibility to protect the ocean, and I’m proud to partner with Plastic Oceans International on this campaign to fight the problem of plastic pollution.”
Located in the South Pacific Ocean between Chile and New Zealand, Easter Island is a UNESCO World Heritage Site on Chilean territory that is considered the most remote inhabited island on the planet. The waters surrounding the island contain one of the highest concentrations of microplastics in the world, most of which originates from sources thousands of miles away. In addition, 20 tons of trash is produced daily on the island, so waste management issues, especially related to the growing tourism industry, are prevalent.
Swim Against Plastic: Easter Island includes a series of beach cleanups to help restore Easter Island’s fragile environment. Plastic Oceans and Breathe Conservation are organizing the events with the island’s local communities and nonprofit organizations, encouraging all residents to participate.
“The planet needs leaders to draw attention to the serious global plastic pollution problem worldwide—threatening the ocean, our food sources and the environment—to understand the dangers of and change how we think about and use plastic,” said Julie Andersen, Global Executive Director, Plastic Oceans International. “By showing the world that our most valued and remote locations are not immune to plastic pollution, our goal is to inspire people to find solutions and eliminate use of single-use plastics that attribute to the problem.”
Plastic Oceans and local residents will conduct a series of programs to determine the specific causes contributing to plastic pollution on Easter Island. Once the roots of pollution are targeted, they will work jointly to find solutions. Results and ways to prevent plastic pollution will be shared throughout local communities, with students and schools, charitable organizations, government officials and businesses.
Anyone can join Swim Against Plastic: Easter Island to get informed, inspired and make changes to solve plastic pollution. Follow the progress of Sarah Ferguson’s world record-breaking swim using #SwimAgainstPlastic. Campaign information is available online at SwimAgainstPlastic.com.
– MyPR
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Recent concert reviews
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From the Country Standard Time Archives
Mel Tellis: a little less talk and a lot more singing is in order
Lancaster Performing Arts Center, Lancaster, Cal., Aug. 15, 2004
By Dan MacIntosh
LANCASTER, CA - No doubt about it, Mel Tillis is a talented performer. He just turned 72 this month, in fact. Yet, he's trim and still has a strong voice. But in concert, Tillis wavers uncomfortably between being a singer and acting the silly, stuttering comedian.
And while many of Tillis' seemingly endless stories about his formative years growing up in Florida were good fun, a more musically centered show would have been far more satisfying.
In addition to his rich singing voice, Tillis is also an underrated songwriter. But since he focused so much attention on telling this audience about his various boyhood friends and one particularly lewd Baptist church experience, he never got around to singing standouts like "Detroit City" or "Ruby, Don't Take Your Love to Town."
He did, however, treat the crowd to "I Ain't Never" and "Heart Over Mind." But by leaving out so many lyrical treasures, the joke was squarely on us.
Musically, Tillis was able to work in a little swing here and a touch of bluegrass there, with the help of his talented Statesiders band. At 13 members strong, this touring unit includes double fiddles, three backing singers and two keyboardists at various points. Tillis played for just over two hours, sometimes accompanying himself on acoustic guitar, but also took 'let's feature members of the band' breaks after every five songs or so. One wonders if Tillis stayed just a little too long (around 13 years) at his Branson, Mo. dinner theater, but not nearly long enough time traversing the meatier stages of America's honky-tonks over the years. This crowd, comprised of mainly senior citizens, seemed to be there solely because of Tillis' celebrity marquee value, rather than out of appreciation for his musical talent. He put on an entertaining show, it's true, but it was a night that left one hungering far something more substantial.
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Maharishi Dayanand Saraswati was a Social reformer and the founder of Arya Samaj. He resolved to uplift the Indian society from the throes of ignorance, illiteracy, injustice. He openly stood up against all the social evils – discrimination on grounds of caste, need, sex, economic status and social bigotry, male chauvinism and religious dominance of higher castes over the backward castes and classes. He fought for the rights of women and opened Kanya Vidyalayas to empower and enlighten them. Thinking on the rich legacy of Swamiji DAVCMC has been supporting and promoting the activities for social upliftment through establishment of socio-cultural & institutions.
These institutions are
Arya Yuvk Samaj
Arya Pradeshik Pratinidhi Sabha
In order to inculcate Vedic values in the learners who are enrolled in DAV Institutions, DAVCMC has undertaken the following initiatives.
Dharam Shiksha
Competitive examinations in Dharam Shiksha
Dharam Shiksha Examination for Schools
Sanskrit Examination for schools
Dharam Shiksha Examination for Colleges.
Chiritra Nirman Shivirs and Jan Chetna Yatras
Social Upliftment Programme
i. For the upliftment of the North-Eastern India
ii. For the underprivileged of the Society
iii. Adult literacy drive and Vocational Training.
Social Concerns:
DAV caters to the needs of urban as well as rural students together with adivasi and tribal children. In tune with the National Literacy Mission , DAV Organization has carried education to the doorsteps of the needy and the under-privileged. Even the remotest areas of India have been provided with basic life skills.
DAV is involved in social welfare schemes, education for the weaker sections and for students from tribal areas, comprehensive plans for the upliftment of tribal people in North East Regions, programmes for the disadvantaged sections of the society and for the mentally challenged children of society.
True to DAV Values, schools have been catering specially to the under-privileged. The DAV Public Schools have provided fee concessions, free text books, free uniforms, free transport, mid- day meals and have also provided non- formal education for the needy.
DAV institutions are conscious about education of girls. Providing job opportunities to women is also a priority. Free vocational training and literacy units are dedicated to hundreds of women of slum areas and gadgets like sewing machines are provided to them for their initial settlement.
Adult education centre and vocational training centres have been set up for financially disabled women and girls. There is a scheme to provide basic literacy and free vocational training in tailoring and embroidery to women and girls living in jhuggi clusters. Mass marriages of poor girls is arranged-. About 1000 girls have been settled through mass marriages. Each couple is given a few articles worth Rs. 20,000/- to set up their homes. An adult education centre has been set up and vocational training is given to financially disabled women and inmates of jails. To kindle social consciousness in students, awareness campaigns are organised against the evils of female foeticide, dowry system, AIDS, child labour, deforestation, global warming to name a few.
Rural Upliftment
In DAV the Yuvas have been enthused to work for a 'Model Village'; - a village that has all the facilities like roads, electricity, water, education and health care unit. A pilot project has been taken up in Village Mando Kheri in District Jind (Haryana). Encouraged by this project, four similar projects have been taken up in Julani Village in District Jind, Fatehpur Village in District Kaithal, Assan and Untla villages in District Panipat. DAV has joined hands with Government of India in promoting Nirmal Gram Yojna.
The students shoulder the responsibility of disseminating literacy, cultivating hygienic habits organizing medical camps, arranging mobile library etc. for the benefit of the rural populace.. Every year thousands of DAV students go to villages and hold short term programmes, such as, adult education, vocational courses, medical check ups and training about health and hygiene.
Apart from this many rural friendly schemes have been undertaken such as provision of:
Medical facilities by setting up dispensaries
Provision of education to school drop out and girl child
Awareness about basic hygiene
Recently a scheme was launched in the district of Jind wherein ration, clothing and vocational training is being given to widows.
DAV Schools have been sensitive to the need of the people suffering from cancer, paralysis or requiring limbs of organ transplant. Help in the form of cash and kind is also extended to the victims of terrorism and fire accident.
DAV Schools have made collections for social organizations such as National Association of Blind, Spastic Society of India, Help-age, Tuberculosis Association of Bihar etc. to contribute to their good work.
Environmental issues like the reduction of pollution and sustenance of the environment have also been taken up by DAV institutions. Several projects like van-mahotsav, ''say no to poly-bags' campaign, 'say no to fire crackers' campaign, water-conservation and anti-pollution drives are regularly carried out by the DAV Schools in order to create awareness not only among the students but the whole community. The students from DAV institutions have carried out sanitation and cleanliness drives in the school neighbourhood also.
National Concerns
DAV has always been a pioneer for any National cause specially- in the hour moments of National Crisis. Whether it be the earthquake at Pauri or Gujarat, the Kargil war, the Orissa tragedy or the Tsunami catastrophe -the DAV has always risen to the occasion by donating generously in the form of cash, kind and voluntary service to alleviate suffering
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Book Review: Horizon Avenue
Book Review Horizon Avenue By Aaron Stern Reviewed by Christopher J Johnson The lyrical photobook, by which I mean those photobooks whose main content is something elucidated through sequence and not necessarily something immediate, is a difficult subject to address. Staples of the lyrically sequenced photobook are: A.) a lack of adroit, in-your-face single images that contain individualized meaning, B.) no or minimalized text, and C.) a progression of story, idea or thought presented through the sequence of the images.
Horizon Avenue. By Aaron Stern. 205-A, 2016.
Horizon Avenue
Reviewed by Christopher J Johnson
Horizon Avenue: San Francisco and other places
Photographs by Aaron Stern. Poetry by Aaron Stern and David Wagoner.
205-A, New York, USA, 2016. 66 pp., 39 four-color illustrations, 5½x8½".
The lyrical photobook, by which I mean those photobooks whose main content is something elucidated through sequence and not necessarily something immediate, is a difficult subject to address. Staples of the lyrically sequenced photobook are: A.) a lack of adroit, in-your-face single images that contain individualized meaning, B.) no or minimalized text, and C.) a progression of story, idea or thought presented through the sequence of the images. Outside of these three central ideas we see a wide range of subject matter and, of course, effectiveness of the methods used.
Now, all this being said, there haven’t been a whole lot of books like this that I have seen and it is essential to keep in mind that this does not pertain to documentary photobooks nor anthological collections, nor books like The Americans or Every Building On the Sunset Strip; those books are subject based while a lyrically based photobook is story based (see article C). However the photobook lends itself to this method of storytelling and as the photobook becomes more known and more utilized, lyrically sequenced photobooks are more numerous.
One artist who has taken up this exceedingly difficult (or perhaps it is just new, implying difficulty simply on account of its newness?) is Aaron Stern. Stern has presented a handful of books that focus on a lyrical sequencing to convey his story; his latest publication is no different in this regard. Horizon Avenue presents the story of a couple travelling to San Francisco, perhaps to move there, perhaps to just visit, but it is the story of a trip taken by a man and a woman and presented from the man’s point of view. Its minimal text, two poems and a fragmented sentence, amplifies this reality, grounds us in the idea of the trip.
Horizon Avenue feels like Hitchcock’s Vertigo or Polanski’s Chinatown without their plot, without the talk and background story, but very much with their West Coast setting. Which is to say, I think, that this book seems like a work of sheer cinematography. Why such books remind me so of movies might be grounded in the idea of images progressing in order to move a story forward and Horizon Avenue achieves this.
The greater part of Horizon Avenue is street views, beach views and views from a car, its secondary matter (or subplot) is the two people who undertook the trip. However the story sinks in slowly, and due to that slowness it arises in our experience more like a memory than a work of photographic art. The images lodge somewhere in the back of the brain and become inseparable from familiar images in similar territory. It ‘reads’ like the recollection of a trip undertaken by anyone.
So far every book that I’ve encountered that takes up this lyrically sequenced form does have one of two effects: that of a dream or that a memory; which is intriguing and brings a lot of credit to the idea of the power of images. Dreams and memories defy language; they arise from a place in us that precedes it and then, when we try to use language to define these things, they lose something or fall apart or are robbed of their essence. I don’t mean to move into the philosophic realm, but it is a difficult subject to relate in words and that difficulty only enhances the sense of the work’s influence.
Horizon Avenue is enormously successful because it transcends language, it arises from a realm more commonly associated with poetry than with prose and expresses something more fundamental than language can express, shared cultural experience. The work is exciting not solely in what it contains, but how it interacts with us and how it finds a place within us.—CHRISTOPHER J. JOHNSON
CHRISTOPHER J. JOHNSON lives in Santa Fe, New Mexico where is manager of photo-eye Bookstore. Aside from this he is a writer for the Meow Wolf art collective and book critic for The CFile Foundation. His first book of poetry, &luckier, will be released by the University of Colorado in November 2016.
Read More Book Reviews
Labels: Book Reviews, Books, Christopher J. Johnson
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CCR Focus Archive
Subspecialty Collections
Immunotherapy: Facts and Hopes
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Phase I Study of the Poly(ADP-Ribose) Polymerase Inhibitor, AG014699, in Combination with Temozolomide in Patients with Advanced Solid Tumors
Ruth Plummer, Christopher Jones, Mark Middleton, Richard Wilson, Jeffrey Evans, Anna Olsen, Nicola Curtin, Alan Boddy, Peter McHugh, David Newell, Adrian Harris, Patrick Johnson, Heidi Steinfeldt, Raz Dewji, Diane Wang, Lesley Robson and Hilary Calvert
Ruth Plummer
Jeffrey Evans
Anna Olsen
Nicola Curtin
Alan Boddy
Peter McHugh
Adrian Harris
Heidi Steinfeldt
Raz Dewji
Diane Wang
Lesley Robson
Hilary Calvert
DOI: 10.1158/1078-0432.CCR-08-1223 Published December 2008
Purpose: One mechanism of tumor resistance to cytotoxic therapy is repair of damaged DNA. Poly(ADP-ribose) polymerase (PARP)-1 is a nuclear enzyme involved in base excision repair, one of the five major repair pathways. PARP inhibitors are emerging as a new class of agents that can potentiate chemotherapy and radiotherapy. The article reports safety, efficacy, pharmacokinetic, and pharmacodynamic results of the first-in-class trial of a PARP inhibitor, AG014699, combined with temozolomide in adults with advanced malignancy.
Experimental Design: Initially, patients with solid tumors received escalating doses of AG014699 with 100 mg/m2/d temozolomide × 5 every 28 days to establish the PARP inhibitory dose (PID). Subsequently, AG014699 dose was fixed at PID and temozolomide escalated to maximum tolerated dose or 200 mg/m2 in metastatic melanoma patients whose tumors were biopsied. AG014699 and temozolomide pharmacokinetics, PARP activity, DNA strand single-strand breaks, response, and toxicity were evaluated.
Results: Thirty-three patients were enrolled. PARP inhibition was seen at all doses; PID was 12 mg/m2 based on 74% to 97% inhibition of peripheral blood lymphocyte PARP activity. Recommended doses were 12 mg/m2 AG014699 and 200 mg/m2 temozolomide. Mean tumor PARP inhibition at 5 h was 92% (range, 46-97%). No toxicity attributable to AG014699 alone was observed. AG014699 showed linear pharmacokinetics with no interaction with temozolomide. All patients treated at PID showed increases in DNA single-strand breaks and encouraging evidence of activity was seen.
Conclusions: The combination of AG014699 and temozolomide is well tolerated, pharmacodynamic assessments showing proof of principle of the mode of action of this new class of agents.
PARP inhibitor
chemopotentiation
Translational Relevance
This phase I study has potentially wide implications within cancer medicine and also in the treatment of inflammatory and ischemic conditions. To the readership of Clinical Cancer Research, it is highly relevant as PARP inhibitors are emerging as novel chemopotentiating and radiopotentiating agents and also drugs that may have single-agent activity in DNA repair-defective familial cancers. This trial is the first-in-class dose-defining study of these agents using target inhibition as the primary endpoint. This hypothesis testing design has subsequently also been evaluated in the phase 0 setting with another agent in the class. Therefore, this article represents importance and interest both in view of being the first full description of biological evaluation and toxicity assessment of a new class of agents and in the development of a new paradigm for dose definition, this subject being the topic of a recent special issue of Clinical Cancer Research (volume 14, number 12, 2008).
Multiple pathways contribute to the repair of damaged DNA (1). Defects in these pathways are a cause of cancer susceptibility (2, 3), but, when intact, their activity is a factor in tumor resistance to widely used DNA-damaging cancer treatments (e.g., cytotoxic drugs and ionizing radiation; ref. 4). Several novel agents are being developed which target DNA repair in an attempt to improve cancer treatment (5), including agents that may exploit tumor DNA repair defects (e.g., BRCA1 and BRCA2) by inducing “synthetic lethality” (6, 7).
Base excision repair is a complex process that repairs DNA single-strand breaks caused by endogenous reactive species and anticancer agents (8). Poly(ADP-ribose) polymerase-1 (PARP) is a key enzyme in this pathway, binding to and being activated by the DNA break, effectively acting as a molecular nick sensor (9), and recruiting additional repair factors. Preclinical evidence has shown that inhibiting PARP potentiates cytotoxics, particularly alkylating agents and topoisomerase I inhibitors, and radiotherapy (10–12). Several PARP inhibitors are in preclinical and early clinical development (13, 14), current clinical investigation of these agents being focused in the area of cancer treatment.
AG014699 (Fig. 1 ), developed by a collaboration among Newcastle University, Cancer Research UK, and Agouron Pharmaceuticals (part of Pfizer GRD), is a prodrug of AG014447, a potent inhibitor of PARP, which has been shown in preclinical models to potentiate the cytotoxicity of temozolomide and irinotecan (15).
Structure of AG014699, phosphate salt of tricyclic indole PARP inhibitor, with Ki < 5 nmol/L.
Temozolomide is an orally bioavailable monofunctional DNA-alkylating agent licensed for the treatment of gliomas and frequently used off-label for malignant melanoma (16). The predominant DNA methylation products formed by temozolomide are N7-methylguanine (70%), N3-methyladenine (9%), and O6-methylguanine (5%). O6-methylation of guanine is the primary cytotoxic lesion causing mispairing with thymine during DNA replication (17); however, high levels of the repair protein O6-alkylguanine alkyltransferase and deficiency in the mismatch repair system can both confer resistance in tumors (18, 19). The N7-methylguanine and N3-methyladenine lesions formed by temozolomide do not normally contribute significantly to its cytotoxicity because they are rapidly repaired by base excision repair.
This study was designed primarily to explore (a) whether a PARP inhibitory dose (PID) of AG014699 was safe and tolerable and (b) the dose of temozolomide that could be given in combination with the PID of AG014699. A combination study was designed based on the preclinical potentiation data discussed above. At the time of design, there were no data suggesting efficacy for the single agent. The primary endpoint for (a) was a pharmacodynamic measure of target inhibition and for (b) was a conventional toxicity endpoint. A single dose of the novel agent was given before the first combination cycle to obtain pharmacokinetic and pharmacodynamic data. Inhibition of the target enzyme was the primary endpoint of the study: translational research exploring proof of principle of mechanism of action using Comet assays for DNA damage levels and pharmacogenomic samples to explore potential difference in pharmacokinetics linked to polymorphisms of the CYP2D6 gene. Therefore, this trial is the first use of this class of agents in humans, being a pharmacodynamically driven phase I study establishing the PID of this compound and showing antitumor activity.
PARP has also been shown to play a significant role in reperfusion injury and the pathogenesis of diabetes and various neurologic conditions (20), and in other disease models, inhibition of PARP is protective against ischemic or inflammatory damage (21, 22). Therefore, the study reported in this article represents the first evaluation of a novel class of drugs with potential in the management of a wide range of human diseases including cancer, diabetes, inflammatory, and ischemic conditions.
Trial design and patient recruitment. The study was done in two parts in accordance with the Declaration of Helsinki (2000). The protocol was approved by a multicenter research ethics committee as well as by Cancer Research UK and by local site institutional review boards. All patients gave written informed consent before participation and undergoing any study-related procedures. Patients were recruited over an 18-month period between 2003 and 2005.
Inclusion criteria included histologic/cytologic proof of malignancy, WHO performance status 0 to 1, age ≥18 years, and adequate bone marrow, liver, and renal function. Patients were excluded if they had prior treatment with temozolomide, nitrosoureas, dacarbazine or mitomycin C, symptomatic brain metastases, primary brain tumors, other current malignancy at a second site, or other significant comorbidity.
AG014699 was given as a 30-min daily intravenous infusion followed by oral temozolomide for 5 consecutive days repeated every 4 weeks. Disease response was assessed according to Response Evaluation Criteria in Solid Tumors every two cycles (23). Toxicity was graded according to National Cancer Institute Common Toxicity Criteria for Adverse Events version 3.0 (2006). Dose-limiting toxicity was defined as a drug-related event occurring in the first 4-week cycle of treatment as follows: neutropenia grade 4 lasting ≥5 days, fever associated (≥38.5°C) with grade ≥3 neutropenia, thrombocytopenia-platelets ≤25 × 109/L, anemia grade ≥3, grade 3 or 4 nonhematologic toxicity, and drug-related death. A standard three-patient cohort dose escalation design was used, but with two separate dose escalations, parts 1 and 2.
Part 1 was open to patients of all tumor types and aimed to establish the PID of AG014699 in peripheral blood lymphocytes (PBL). Patients received a single intravenous dose of AG014699 a week before starting combination therapy (day -7) to investigate the toxicity and pharmacokinetic and pharmacodynamic profile of AG014699 alone. The temozolomide dose was fixed at 100 mg/m2/d for this part of the study to allow for the possibility that PARP inhibition might increase the myelotoxicity of temozolomide. The PID was defined as maximal achievable (at least 50%) reduction in PARP activity 24 h after this first dose of AG014699 with no increase in the degree of PARP inhibition over the preceding AG014699 dose level.
Once the PID had been identified, patients received this dose of AG014699 and the dose of temozolomide was escalated until the maximum tolerated dose of the combination was established or the temozolomide dose reached a maximum of 200 mg/m2 (the standard single-agent dose for this schedule). In part 2 of the study, participation was confined to patients with chemonaive melanoma with tumor deposits that were amenable to pretreatment and post-treatment biopsy.
PARP activity assay. PARP enzyme inhibition was assessed in PBL at baseline, end of infusion, and 4 to 6 and 24 h after dosing on days -7, 1, and 4 of cycle 1 during part 1 of the study to establish the PID. An additional sample on day 8 (3 days after last dose of AG014699) was taken at the PID to explore the duration of inhibition. Paired tumor biopsies were obtained from all patients in part 2 of the study to examine target tissue PARP inhibition, biopsies being taken at baseline and 4 or 24 h after treatment with AG014699. All samples were analyzed using a previously validated and published activity assay (24) employing quantitative immunologic detection of PAR formation ex vivo.
AG014699 and temozolomide pharmacokinetics. Plasma samples for pharmacokinetic analysis were collected from all patients on day -7 and on days 1 and 4 of cycle 1 (combination treatment) pre-infusion, 15 min, end of infusion (T0), 15 min, 30 min and before temozolomide dose, 60 min, 2 h, 4 h, 6 h, 8 to 12 h, and 24 h post-infusion. Validated and published methods were used for the measurement of temozolomide plasma concentrations (17). Plasma samples were also analyzed for AG014447 concentrations (free base of AG014699) by high-performance liquid chromatography and tandem mass spectrometry analysis. Temozolomide and AG014699 pharmacokinetics were characterized by noncompartmental methods using WinNonlin version 3.1.
Pharmacogenomic analysis for metabolic phenotype of CYP2D6. A single 5 mL blood sample was collected at baseline in EDTA and frozen immediately at -20°C for pharmacogenomic analysis. TaqMan allelic discrimination assays were developed and validated for six of these alleles (CYP2D6 *3, *4, *6, *7, *8, and *10).
DNA strand break assessment. The method used for the alkaline Comet assay was a modified version of that described originally by Olive et al. to detect DNA strand breaks (25). An increase in Comet tail size shows an increased percentage of fragmented more mobile DNA within the cell, indicating the degree of DNA strand breaks.
Slides were stained with SYBR Gold and the percentage DNA in the tail and Olive moment was determined using KOMET5 software (Kinetic Imaging). Fifty cells from two slides were counted for each sample and the mean percentage tail DNA and Olive Tail moment was calculated.
Data analysis and compilation. Regular teleconferences were held among the four investigating sites, Cancer Research UK (study sponsor) and Pfizer GRD during the study at to discuss patient safety and study status. All data listings were made available to the investigators for preparation of this article. The patient demographics, treatment summaries, toxicities listings, and response data were extracted from this verified data set by the lead author (R.P.), an investigator at one of the clinical sites. Pharmacodynamic assays were done at the principal investigator's research site. Pharmacokinetic analyses were done by a contract research organization (Quintiles). All analyses and raw data were made available to the lead author and chief investigator for review. The first draft of this article was written by the lead author and has been reviewed and approved by all other investigators.
Patient demographics and treatment. A total of 32 patients (21 males and 11 females; mean age, 52 years) were recruited and received at least one dose of AG014699: 17 patients in part 1 and 15 in part 2 of the study (Table 1 ). All patients were evaluable for toxicity. Twenty-nine patients received two cycles of treatment and were evaluable for tumor response. Dose levels and the number of cycles delivered are described in Table 2 .
Patient demographics
Dosing and toxicity summary
In part 1, the dose of AG014699 was escalated through five dose levels. No dose-limiting toxicity was observed and the PID was established as 12 mg/m2/d. In part 2 of the study, it proved possible to administer 200 mg/m2 (the licensed dose) of temozolomide with the PID of AG014699 without dose-limiting toxicity, so the trial had reached its primary objective. One further dose level, increasing the dose of AG014699 by 50% to 18 mg/m2/d in combination with 200 mg/m2/d temozolomide was explored to establish whether more profound tumor PARP inhibition could be achieved. In view of the toxicities described below at this dose, 12 mg/m2/d (the PID) AG014699 with 200 mg/m2/d temozolomide × 5 every 28 days is recommended for future studies.
Toxicity. No toxicity of any kind attributable to AG014699 alone was observed. The combination with temozolomide was well tolerated with no toxic deaths. Myelosuppression, the dose-limiting toxicity predicted by preclinical models, was observed at the maximum dose of AG014699 evaluated (18 mg/m2/d given with 200 mg/m2/d temozolomide): one patient suffered grade 4 thrombocytopenia and neutropenia, with grade 3 neutropenic fever, but the patient made a full recovery by day 29. Three other patients in the cohort had cycle 2 delayed by 1, 8, and 14 days, respectively, due to grade 3 neutropenia with slow recovery of the WBC count. These 3 patients continued on treatment with a dose reduction, receiving at least two further cycles without toxicity. Three patients with tumor responses on part 1 of the trial had the dose of AG014699 increased without subsequent toxicity.
Pharmacokinetics. The pharmacokinetics of AG014447 (the free base of AG014699) is detailed in Table 3 . The data are summarized giving mean values for the treated population (CV%). The drug showed linear pharmacokinetics with the Cmax at the end of the infusion and a mean terminal half-life of 9.5 (50.4) h. The mean volume of distribution was 212 (65.9) L, indicating extensive distribution into tissues, and the mean percentage of dose recovered over 24 h in the urine after a single dose was 11%, indicating that the kidneys were not the major elimination route. Further analysis showed that AUC0-24 h normalized for actual dose and AUC0-24 h normalized for mg/m2 dose did not correlate with body surface area and intersubject variability was equivalent (54% in both cases), suggesting that AG014699 can be given either as a fixed dose or based on surface area. There is no evidence that temozolomide has an effect on AG014447 pharmacokinetics either after a single dose or multiple doses.
Pharmacokinetic summary of AG014699
Temozolomide pharmacokinetics was similar to those reported previously, suggesting that they were not affected by the coadministration of AG014699 (data not shown).
AG014447 was detectable in all tumor biopsy homogenates (range, 5-110 ng/g tumor protein) in samples taken 5 h (24 h in 3 patients) after the administration of the drug. Concentrations varied up to 20-fold between patients treated at the same dose level and there was no apparent correlation with the degree of PARP inhibition.
Pharmacodynamics. PARP inhibition in PBL was seen at all AG014699 dose levels studied with profound inhibition (>90%) at the end of infusion. At the lower dose levels, there was recovery of enzyme activity over 24 h; however, at the doses above 8 mg/m2, no recovery was observed over the 24 h (Fig. 2A and B ), indicating that PARP was inhibited throughout the period temozolomide exposure induces DNA strand breaks (26). Analysis of PARP inhibition on cycle 1 day 8 in patients dosed with 12 mg/m2/d showed that enzyme activity had recovered in PBL to ∼50% of baseline 72 h after the last dose of AG014699.
Pharmacodynamic effects of AG014699. A to C, summary of PBL and tumor PARP inhibition measured using PARP activity immunoassay. A and B, representative plots from days -7, 1, and 4 of the first treatment cycle from patients treated with 2 mg/m2 (A) and 12 mg/m2 (B). C, summarized data from tumor biopsies taken 5 h after the first dose of AG014699 at the dose levels indicated. Data expressed as percentage activity compared with pretreatment biopsy in the same individual. D, DNA damage in peripheral blood mononuclear cells by cohort. Blood was sampled on day 4 of the first treatment cycle before (hatched), 4 h after (white), and 24 h after (black) temozolomide dosing. Mean of up to 6 patients.
Based on surrogate tissue enzyme inhibition, 12 mg/m2 was established as the PID for part 2 of the study. In part 2, paired tumor biopsies were taken in all patients and PARP inhibition of >50% was observed in all biopsies, and a trend toward AG014699 dose dependency was observed (Fig. 2C), small numbers making formal statistically comparison not feasible. Although two doses of AG014699 were investigated in part 2 (12 and 18 mg/m2), such profound and consistent inhibition was observed in peripheral blood mononuclear cells. No correlation has been possible between the degree of inhibition in peripheral blood mononuclear cells and tumor.
Comet analysis in PBL showed evidence of DNA damage in all patients treated with AG014699 and temozolomide but not AG014699 alone. The duration of DNA damage was dependent on the dose of AG014699; at lower doses (1-8 mg/m2), tail size was smaller at 24 h than at 4 h on day 1 (mean decrease, 8%), indicating repair of some strand breaks, whereas at PID (12-18 mg/m2), Comet tail size was maintained or increased at the later time point (mean increase, 3%; P = 0.03). Additionally, there was evidence that DNA damage was retained during the treatment week with an increase, compared with baseline, in percentage DNA in the Comet tail before treatment on day 4, significantly more damage remaining at 12 mg/m2 than for lower doses (P = 0.002, t test; Fig. 2D).
Pharmacogenomics. The genotype of CYP2D6 was estimated in 26 of 32 patients. In 22 patients, the homozygous wild-type for both of the CYP2D6 alleles or a heterozygous genotype containing at least one wild-type allele was observed. In the remaining 4 patients (patients 3, 5, 11, and 25), mutations in the CYP2D6 G1846A allele, designated as CYP2D6 *4, were observed. These patients were homozygous for the *4, *4 genotype and were predicted to be associated with poor metabolism. Three of these 4 patients were in the group who benefited from the combination, receiving 8, 8, and 16 cycles, including 2 patients with melanoma who had confirmed partial and complete responses, respectively. The fourth patient with the 4* genotype died after his test dose of a disease-related acute complication (bronchial obstruction). However, pharmacokinetic analysis showed that the exposure measured by AUC0-24h was similar between patients with predicted extensive or poor metabolism.
Response. Clinical benefit was observed for several patients in parts 1 and 2 of the study. There was one documented complete response and one partial response in patients with metastatic melanoma (both patients had received no prior chemotherapy for melanoma) and a further partial response in a patient with a desmoid tumor (treated previously with extensive surgery and imatinib). Seven further patients had prolonged disease stabilization (≥6 months), 4 with melanoma and 1 each with prostate cancer, pancreatic cancer, and leiomyosarcoma.
This study is the first to report the clinical and pharmacologic effects of PARP inhibition in humans, establishing a PID of AG014699 in a surrogate tissue (PBL) and confirming this inhibition in tumor deposits from melanoma. Dose definition in this phase I trial was established using a pharmacodynamic endpoint rather than more classic toxicity or pharmacokinetic variables. This endpoint of PARP inhibition was also used as the primary endpoint in the phase 0 study of ABT-888 done at the National Cancer Institute (27). The PID was established in combination with half-dose temozolomide due to safety concerns based on preclinical studies and previous experience of inhibiting DNA repair with MGMT inactivators, where enhancement of myelotoxicity and a significant reduction in the maximum tolerated dose of cytotoxic agents was reported with O6-benzylguanine (28, 29) and lomeguatrib (30). The dose-toxicity relationship for temozolomide is steep, 200 mg/m2/d being well tolerated but 225 mg/m2/d causing significant myelosuppression (31). It would appear that enhanced temozolomide induced myelosuppression observed in this study when patients were dosed with 200 mg/m2 temozolomide and 18 mg/m2 AG014699, with 1 patient developing pancytopenia and 3 patients having delayed recovery of neutropenia, an unusual toxicity with single-agent temozolomide (32). There was no correlation between toxicity and pharmacokinetic variables, and all patients dosed with 18 mg/m2 AG014699 showed similar peripheral blood mononuclear cells and tumor PARP inhibition patterns. This increase in toxicity is presumably due to persistence of unrepaired DNA strand breaks in bone marrow stem cells. However, the relative lack of toxicity observed in this study, and the ability to deliver an enzyme inhibitory dose of AG014699 in combination with full-dose temozolomide, is encouraging and in marked contrast to studies with MGMT inactivators (33–35). The complete absence of any symptomatic or laboratory toxicities as a result of PARP inhibition on its own is also encouraging for the future use of PARP inhibitors in indications when they are given as single agents.
There was no evidence of increased PARP inhibition between the dose levels of 12 and 18 mg/m2 AG014699 in the surrogate pharmacodynamic tissue (peripheral blood mononuclear cells), whereas a trend to dose-dependent increase in inhibition was observed in tumor biopsies. This highlights some of the difficulties in using an easily accessible but surrogate tissue to establish a pharmacodynamically defined dose of an intravenous agent. PARP is overexpressed in malignant tissues (36, 37), overexpression of a target being frequently used as a rationale for anticancer drug development. However, there is little preclinical data into its role within the tumor and it is not known to what degree PARP must be inhibited within the tumor to prevent base excision repair. In preclinical experiments, xenograft PARP inhibition of 50% was observed at the most efficacious dose of AG014699 combined with temozolomide, where cures were seen in animals bearing SW620 tumors (15). Thus, our PID threshold was set at ≥50% inhibition, but of necessity in the surrogate tissue, then confirmed in paired tumor biopsies.
The strategy for chemopotentiation studied in this trial relies on there being a selective advantage of inhibiting PARP in the tumor compared with normal tissue. There is evidence that tumors express high levels of several DNA repair proteins, including PARP (24), resulting in chemoresistance (38–40). The majority of the DNA adducts caused by temozolomide (N3-methyladenine and N7-methylguanine) are rapidly repaired by base excision repair (41). Inhibition of PARP during temozolomide exposure prevents the repair of the strand breaks that are formed after base excision, thereby triggering apoptosis. A phase II study of AG014699 with temozolomide in metastatic melanoma has completed recruitment and preliminary results do suggest encouraging response rates (17% partial response and a further 17% patients having stable disease for ≥6 months) and progression-free survival (42).
Although this study was designed to establish the safety of using AG014699 in combination with a cytotoxic agent, there are emerging preclinical data suggesting that targeting DNA repair may allow exploitation of tumor-specific DNA repair defects. Specifically, PARP inhibitors are highly and selectively toxic to cells deficient in homologous recombination repair, which includes cells lacking BRCA1 and BRCA2 major causes of familial breast and ovarian cancer (6, 7, 43). These exciting new data have widened the potential cancer applications of this emerging new class of agents. In addition, there is a wealth of preclinical data showing a protective effect of PARP inhibition in the face of massive DNA damage after an ischemic insult (21, 44, 45), and once the clinical safety of these agents is established, they are likely to find very wide therapeutic application (20, 46).
H. Steinfeldt, R. Dewji, and D. Wang are employed by Pfizer GRD. N. Curtin, H. Calvert, D. Newell, A. Boddy, and R. Plummer have received commercial research grants from Pfizer GRD. H. Calvert, D. Newell, N. Curtin, and R. Plummer (AG014699) have an ownership interest with intellectual property for compound series, jointly held between New Castle University and Cancer Research Technology.
We thank the patients, research nurses, and data coordinators involved in this study for the help and support and Prof. Alex Bürkle for the generous gift of the 10H PAR antibody used throughout the study for pharmacodynamic analysis.
Grant support: Cancer Research UK, Department of Health England, and Pfizer GRD.
The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked advertisement in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
Note: R. Plummer and C. Jones contributed equally to this work.
Previously published in abstract form only and presented at the following major scientific meetings: American Society of Clinical Oncology 2005 (poster presentation) and National Cancer Institute/European Organisation for Research and Treatment of Cancer/AACR Molecular Therapeutics Philadelphia Meeting 2005 (oral presentation). R. Plummer, M. Middleton, et al. First in human phase I trial of the PARP inhibitor AG-014699 with temozolomide (TMZ) in patients (pts) with advanced solid tumors. J Clin Oncol 2005;23:208S. R. Plummer, M. Middleton, et al. Final clinical, pharmacokinetic and pharmacodynamic results of the phase I study of the novel poly(ADP-ribose)polymerase (PARP) inhibitor, AG014699, in combination with temozolomide. Clin Cancer Res 2005;11:9099S.
Received May 14, 2008.
Revision received July 1, 2008.
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Bosken CH, Wei Q, Amos CI, Spitz MR. An analysis of DNA repair as a determinant of survival in patients with non-small-cell lung cancer. J Natl Cancer Inst 2002;94:1091–9.
Newlands ES, Stevens MFG, Wedge SR, Wheelhouse RT, Brock C. Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials. Cancer Treat Rev 1997;23:35–61.
Plummer ER, Lorigan P, Evans J, et al. First and final report of a phase II study of the poly(ADP-ribose) polymerase (PARP) inhibitor, AG014699, in combination with temozolomide (TMZ) in patients with metastatic malignant melanoma (MM). J Clin Oncol 2006;24:456s.
Fong P, Spicer J, Reade S, et al. Phase I pharmacokinetic (PK) and pharmacodynamic (PD) evaluation of a small molecule inhibitor of poly ADP-ribose polymerase (PARP), KU-0059436 (Ku) in patients (p) with advanced tumours. J Clin Oncol 2006;24:3022.
Pacher P, Liaudet L, Mabley JG, Cziraki A, Hasko G, Szabo C. Beneficial effects of a novel ultrapotent poly(ADP-ribose) polymerase inhibitor in murine models of heart failure. Int J Mol Med 2006;17:369–75.
Nakajima H, Kakui N, Ohkuma K, Ishikawa M, Hasegawa T. A newly synthesized poly(ADP-ribose) polymerase inhibitor, DR2313 [2-methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one]: pharmacological profiles, neuroprotective effects, and therapeutic time window in cerebral ischemia in rats. J Pharmacol Exp Ther 2005;312:472–81.
Woon EC, Threadgill MD. Poly(ADP-ribose)polymerase inhibition—where now? Curr Med Chem 2005;12:2373–92.
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Tommy boy mp4 download
Tommy boy mp4 download. Tommy Boy 1995 1080p BluRay H264 AAC 2019-02-13
Wednesday, February 13, 2019 3:37:35 AM Willis
Tommy Boy (1995) [BluRay] [720p] YIFY » Uploadgig Downloads
You'll laugh the hardest you've ever had, and you'll wonder why you hadn't seen it earlier. I won't go into great details about this film, basically because there aren't many worth mentioning. The label is credited with launching the careers of notable legends Afrika Bambaataa, Coolio, Queen Latifah, House of Pain, De La Soul, and Naughty By Nature. I was one of those maligners, I must admit. It's ugly to look at and boring as hell! Chris Farley was a great comic actor who had amazing potential - he will be sadly missed. The movies we have though, give us a glimpse of what could have been. He is given a job at this father's auto part company, even though he isn't very smart.
Browse Tommy Boy (1995) 720p YIFY Movie Reviews
I guess they can't, I guess they won't I guess they front; that's why I know my life is out of luck, fool! The scene where he sets the cars on fire, and later the deer scene, make for a pure laugh riot. There is not one moment of this film that I didn't like. His father, Big Tom Callahan, owns an auto parts factory in Ohio. Chris Farley plays Tommy Callaghanhe mega successful company 'Callaghan Auto Parts' has to go on the road to stop the company going under after Big Tom dies. This movie actually is quite good and well written. That's really all I have to say about this film.
I don't understand the low rating on this site. When Tommy arrives back home, he finds he has a position at the factory waiting for him. Years after his death, I still hold that to be true. But when Big Tom dies, the factory threatens to go under unless the new brake pads are to be sold. This produces a hilarious argument culminating in Spade smacking Farley in the head with a 2x4.
Download Tommy Boy (1995) YIFY Torrent for 720p mp4 movie
Richard, a smart and sarcastic man, is reluctant to help Tommy. Chris Farley was hilarious in this film, him and Spade are magic together. And now there's Deuce Bigalow: Male Gigolo followed by sequel Deuce Bigalow: European Gigolo. Tommy, a hopeless 20 something who just graduated college returns to his hometown of Sandusky, Ohio. An old Carpenters song is playing on the radio and the two are emotionally singing along with it. There are plenty of great passages that I hear everyday from this movie.
Tommy Boy (1995) Full Movie Online Free Streaming
Spade really has some good one liner sarcasms that are gut splitting, and Farley has idiotic one liners the are hilarious. TommyBoyRecords Coolio HipHop TommyBoy GangstasParadise goldenera. There is no life here. There are almost no laughs. After Big Tom suddenly dies, Tommy and Richard have to try to sell half a million auto parts to save the company from bankruptcy. This is one of the few movies to have ever made me laugh until I cry. Will Tommy save the company, or will the factory, and the town, go under? This movie is full of great laughs and everybody will enjoy it.
BRRIP Tommy Boy (1995) : 1995 Movies
But when Big Tom dies, the factory threatens to go under unless the new brake pads are to be sold. That alone is funny enough, then the hood of the car pops up and they skid wildly out of control. It was so sad about Farley's untimely death in 1997, but a credit to his genius is 'Tommy Boy'. Tell me why are we so blind to see That the ones we hurt are you and me? They contrast each other perfectly. Perhaps soon there will be Spiderman: European webs are Hotter. Yes it's not particularly sophisticated. The only time I have ever laughed harder in public was during the snowman scene in Dumb and Dumber.
Tommy Boy (1995) 1080p Download YIFY movie torrent
The plot is embarrassingly bad. His father, Big Tom Callahan, owns an auto parts factory in Ohio. When Tommy arrives back home, he finds he has a position at the factory waiting for him. If you haven't seen Tommy Boy, I just feel sorry for you. This is your typical junk comedy. Yes, from the whole cast. This movie was dead on arrival.
He died before being able to develop fully into a great comedic actor. You will laugh your butt off. This is one of my favourite comedy films. His dad also introduces Tommy to the new brake pad division of the factory and to Tommy's soon-to-be stepmother, Beverly Barish-Burns Bo Derek , and her supposed son Paul Barish Rob Lowe. Also, Black Sheep is another great one with Chris Farley and David Spade.
The jokes are hilarious and you will be laughing every minute of this movie. In order to save the company Tommy must sell at least a half a million of the company's break pads in order to pay off the bank. There's really not a whole lot more to say than that. Tragedy strikes though, when Tommy's father dies and the company is in danger. It has a good storyline, good acting, great scenery, adventure and some brilliant gags! I pretty much know it by heart. But you can completely ignore that and simply luxuriate in Chris Farley's antics. Tommy Boy was the best of Farley's cinematic efforts.
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ELIZABETH MITCHELL FAN CLUB
Elizabeth Mitchell Fan Club » Interviews » Metrosource
31 Jul, 2009 5:37
, by EMfc ·
Metrosource
For us, Elizabeth Mitchell will always be the girl who made out with a young Angelina Jolie in Gia, but as Juliet on ABC’s Lost, Ms. Mitchell tends to run around the island looking fierce. So we were shocked to find her to be laid-back and giggly — way more bubbly than bad-ass.
Did you feel any pressure coming on board a pop-culture phenomenon like Lost?
I think I probably just refused to feel it too much. I just had a baby like six months before, and I was too sleep-deprived to care.
That kinda works for the character.
Yeah, fairly insane. But I think I was just like, “Well, I’ll do this, then. That sounds great,” not realizing how huge [the show] was.
Tell us about Juliet.
Well, I think she’s very smart, very loyal. She’s trying to figure something out: how to get home, for the most part. But she can’t find any way to click her heels together.
We think she’s one of the more fascinating characters on the show.
A lot of it, of course, is the writing, but I think that I get so excited because there’s actually something real to play.
You don’t often find such complicated characters on network television.
You really don’t, and I didn’t think she was going to be that. I mean, Juliet didn’t start out that way, so I got more and more interested as I was getting scripts. I was like, “Really? They want me to do this?” It was really unexpected and very cool.
Juliet has this scary-slash-intense thing going on.
She does have a kind of intense way of watching people, which is one of the more interesting things about her to play. I think that kind of stillness isn’t something people easily do. We constantly try to fill spaces and kind of make everything okay.
How much of her backstory did you know when you started playing her?
They kind of fed it to me bit by bit, but I remember that I had a lot of it figured out. You just had to learn to get that instinctive feel for her, and slowly you saw who this person was. And of course, [the show’s writers] sit you down at first and they talk to you, and they ask you all sorts of things about yourself. They take a lot of what they’re doing — because they have this whole huge blueprint — and they put you in there. They talk about things that affect you, like, “You have a sister,” and so on. And I think that’s one of the brilliant things that they do, is they watch the people who work for them carefully, and they play to their strengths.
Do you ever get any crazed overreactions from fans?
You know, at first maybe a little bit more so because Juliet was such an antagonist. At least now she seems to be more accessible. I was on the playground with my son, and I was wearing an old-lady dress and huge hat, and this woman looks at me and gasps,“You’re Juliet!” And I’m like, “Yeah.” And she says, “Oh, my God, I thought you’d be in head-to-toe leather and riding a motorcycle.” And I was all, “No, I’m sorry. This must be horribly disappointing. I apologize.”
Yeah, but so much of the time onscreen, you guys all look sweaty and filthy.
Oh, yeah — we spend a great deal of time looking awful.
Well, that must cut down on being recognized. We’re assuming you don’t run around looking filthy all the time.
I do! Well, not filthy, but I usually look tired, and I have no makeup on. It’s when I’m really dressed up that no one recognizes me. I was walking through the airport one time when I had a press thing, and I had on what I love to wear: huge high heels and a great dress. I didn’t get stopped once.
Who’s a better kisser: Matthew Fox or Angelina Jolie?
Well, that’s not really a fair question. I mean, I barely got to kiss Matthew. There was a lot of psychological stuff behind it, but as far as just letting loose and getting to kiss, it never happened. I don’t know that I can answer that fairly, but I will say that Angelina was lovely to kiss.
So the answer is Angelina?
But Matthew was lovely, too. I mean how can you not [think so], with Matthew? You can sort of drown in all that softness with him, but then he still has that masculine, firm thing going on.
Source: Metrosource
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Most Famous Roles
» The Purge: Election Year (Movie) 2016
» Crossing Lines (TV Show) 2015
» Once Upon A Time (TV Show) 2014
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» V (TV Series) 2009-2011
» Lost (TV Series) 2006-2010
Elizabeth Mitchell is a phenomenally talented American actress, born in 1970, probably best known for her roles as the fan favourite ill-fated and one of the most ambiguous characters of tv Dr. Juliet Burke on the hit show “LOST”, and the outstanding Snow Queen on “Once Upon A Time“.
She was the lead in the movie “The Purge: Election Year“, which brought in $80 million (8 times its budget) only in USA.
She’ll start filming a new Christmas movie (Read what she told us about it) in July and has just completed the movie “Witch Hunt“. She also has two movies in post-production “Never Too Late!” with Ellen Burstyn and “What We Found“.
You probably remember her also as the kick-alien-ass FBI Agent Erica Evans on “V“, the scientist Rachel Matheson on “Revolution” and the inspector Carine Strand on the action/crime series “Crossing Lines”.
With a B.F.A. in Acting she spent 15 year doing theatre before she got in front of the camera. Her credits include: GIA (1998), THE LINDA MCCARTNEY STORY (2002), FREQUENCY (2000), NURSE BETTY (2000), SANTA CLAUSE 2 (2002), SANTA CLAUSE 3 (2006), but also numerous guest appearances and recurring much discussed characters on well-established shows as THE EXPANSE, BLINDSPOT, ER, LAW & ORDER: SVU, BOSTON LEGAL, EVERWOOD, C.S.I., JAG and HOUSE MD.
With numerous credits from theatres, TV series and movies, Elizabeth Mitchell has been blessing our small and big screens for more than 30 years.
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Elizabeth Mitchell Fan Club is a fansite, proudly run with the blessing and the support of Elizabeth Mitchell. Read what she said in public about her fansite and about our dinner with her.
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Rolls-Royce Takes the Sport-Utility to New Heights
A smooth ride and bells and whistles galore make the Cullinan more than outdoor-ready
Written by Steve Siler
We’re not sure if Rolls-Royce customers are tailgating types, and of those who might be, it’s hard to imagine many of them getting their pregame buzz on in a college stadium parking lot, grabbing cold, wet beers—or even a bottle of Cristal—from the boot of their Rolls. Certainly, better choices for such shenanigans exist among the seven to 10 other vehicles owned by the typical Rolls-Royce customer.
Or is there? Among the numerous amenities of the all-new Rolls-Royce Cullinan that far surpass the realm of necessity is the “Viewing Suite”—two folding seats that, at the touch of a button, motor out from the “Recreation Module” cartridge mounted beneath the cargo floor and unfold, facing outward, while a small cocktail table rises between them. Homecoming will never be the same.
Rolls-Royce has designed various other modules that may be stored at home and swapped into the Cullinan on a lark, should the customer prefer drone photography, hiking, rock climbing, BASE jumping, snowboarding, wakeboarding—even volcano boarding (!). And in case Rolls has not, in fact, anticipated one’s specific sybaritic desire, customers may spec out their own custom Recreation Modules to suit whatever activities they consider “recreation.”
But that Viewing Suite—an estimated $25,000 expenditure on top of the roughly $325K starting price for the Cullinan—should prove particularly popular, we surmise, especially to drivers who are comfortable driving off-road. As the company’s first-ever model to come standard with all-wheel drive, adjustable air suspension informed by stereoscopic cameras, hill descent control, four-camera surround view with “helicopter mode,” infrared night vision that detects both pedestrians and wildlife, water-fording capability of 21 inches, and an “Everywhere” button that sets the Cullinan up for optimal traction based on terrain, the vehicle may take them places they could never reach in a Phantom and where the Viewing Suite could be put to very good use indeed.
We got the chance to reach some of those places in the Cullinan during its global media debut in gorgeous Jackson Hole, Wyoming, where we experienced, among other things, what it’s like to drive a Rolls-Royce that is—clutch pearls—dirty. While we’d never wear the record-breaking mega-diamond for which the Cullinan is named out on trails this muddy and strewn with debris, we would happily climb Snow King again in this Rolls, even on the standard all-season tires; ditto any of the miles of muddy, rutted Wyoming trails, which, in spite of their rocks, water crossings, and undulating surfaces, never pitched the Cullinan’s body into a fit of shuddering or tossed our heads around violently. For tougher stuff, the eight-speed automatic has a “Low” button that holds second gear. Sure, the Cullinan is the most expensive production SUV in history, but powered by Rolls-Royce’s trusty, torquey, and silent 563-horsepower 6.75-liter V-12 and aided by technology, it is not as precious as one might expect.
The Cullinan is also not as numb on the road as one might expect, given that it’s a three-ton SUV, and a Rolls-Royce SUV to boot. Indeed, the vehicle feels taut—never harsh, just mannerly and crisp—more like a Ghost than the pillowy Phantom. Steering is well weighted and accurate, but at 79 inches across—roughly the same as a full-size pickup—the Cullinan always feels big, especially on narrow two-laners. It’s arguably at its best where there are no lanes—i.e., off-road.
It even looks better with a little grit, because, to be candid, the elegance for which Rolls-Royces are known is muted to some degree in this high-bodied form. Its aluminum-intensive “Architecture of Luxury” structure also underpins the $100K-pricier Phantom, but a foot and a half less length and seven inches more height give the Cullinan a chunkier profile. All traditional Rolls-Royce cues are present—the Pantheon grille, stern-looking headlamps, pronounced shoulder, power-operated “coach” doors, small rectangular taillamps, tapering bustle-back rear end—but the proportions seem somewhat awkward, like those of the high-roofed Bentley limousine the Queen of England uses when Her Majesty allows herself to be seen being transported in public. That said, those high walls make great canvases for splattered mud, and the Spirit of Ecstasy, a.k.a. Eleanor, looks rather awesome with mud on her face. Good thing each Cullinan is coated with three coats of paint and two layers of protective clear coat.
There’s little to question inside. Like most Rolls-Royces, there isn’t much of the interior that’s not covered by unspeakably soft bull hides (at least nine per Cullinan, according to Rolls-Royce), gorgeous wood veneers, or authentic metal trim, with the ambience changing considerably depending on the color scheme and level of sheen on the wood and metal. Whether in front or back, one sits upon what feels more like a personal cloud than a chair, and as with Rolls’s Ghost and Phantom sedans, the rears can be combined bench-style for three-across capacity, or as individual thrones separated by a refrigerator and cabinetry containing whiskey glasses and other bar items. Stadium seating and tall, vertical windows provide a commanding view, and should the paparazzi attack, power curtains are available to shut them out. Buttons on the front seatbacks deploy motorized tray tables that feature integrated touchscreen tablets for in-seat entertainment, navigation, or web browsing via the Cullinan’s 5G-capable hotspot. And, of course, there’s no pleasure quite like running one’s toes through the deep lamb’s wool carpets in a Rolls-Royce.
Deliveries of the 2019 Rolls-Royce Cullinan are slated to begin about the time you read this. Watch for them on the road, on a trail, or perhaps at a tailgate party near you.
The 2019 Super-Sport-Utilities: Lamborghini Urus and Porsche Cayenne
While the Rolls-Royce sport-utility vehicle featured in this issue is neither sporty nor all that utilitarian, Lamborghini’s new SUV, the Urus—pronounced “ooo-rus”—promises to be at least the former. Lamborghini is even characterizing it as a super-sport-utility vehicle. And that’s a fair comment coming from Lamborghini, which knows a bit about super-sport things.
Starting around $200K, the Urus isn’t Lamborghini’s first SUV, but it’s the company’s first since the tanklike LM002 of the late 1980s/early 1990s, a.k.a. the Rambo Lambo. Unlike the LM002, which used the Countach’s sonorous but persnickety V-12, the Urus uses a wickedly powerful turbocharged V-8 with 641 hp, roughly 200 ponies mightier than the LM002’s V-12. Thus equipped, the Urus should be good for 0-to-60 mph sprints of about 3.5 seconds, half the time it took the LM002. The Urus’s hexagon-driven cabin decor is stunningly different from those of the similarly priced Bentley Bentayga and similarly sport-oriented Porsche Cayenne, corporate cousins of the Urus within the Volkswagen AG family.
Lamborghini Urus Dynamic Launch in Palm Springs, California.
Speaking of the Porsche, the Urus might not exist if not for the Cayenne, which was the first SUV to prove that a truly sporty sport-utility vehicle was possible. For 2019, the Cayenne is all-new and, like the Urus, designed for sportier-minded drivers. While the top dog Cayenne Turbo shares much of its turbocharged V-8 with the Urus (and the Bentley), it’s limited to “just” 550 hp, so as not to upstage the others, both of which are roughly $75K pricier. The Cayenne and Cayenne S models will also be offered with turbo V-6s with 340 and 440 hp, respectively, starting around $75K.
Visually, the new Cayenne appears thicker but is actually lower and narrower, yet still as sleek as a missile. It’s more spacious and far more refined inside. Both of these particularly sporty sport-utes are on sale now.
Money,
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In between sets from Jessie Reyez, Kacey Musgraves, and The 1975, check out these activations at Governors Ball More
Tour DuJour: Neverland Ranch
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Posts matching tags 'cartography'
A few London transport map links: here there is a detailed, zoomable map of the London Underground and surface railways, showing the locations of stations (both operational and closed) and tracks.
Meanwhile, the Green Party's candidate for Mayor of London has an interactive map showing how far London's bicycle hire system would reach if it were the size of Paris's; which is to say, quite a bit further, particularly to the north and south. Perhaps it'd even be possible to live near a Boris Bike station without being made of money.
¶ cartography cycling geography infrastructure london railway transport tube 0
Britain's most senior cartographer has railed against electronic maps, arguing that they obliterate the rich geography of Britain, reducing an ancient landscape filled with history to a set of roads:
Churches, cathedrals, stately homes, battlefields, ancient woodlands, rivers, eccentric landmarks and many more features which make up the tapestry of the British landscape are not being represented in online maps, which focus on merely providing driving directions, said Mary Spence, President of the British Cartographical Society.
"Corporate cartographers are demolishing thousands of years of history, not to mention Britain's geography, at a stroke, by not including them on maps," she said. "We're in danger of losing what makes maps unique; giving us a feel for a place."
While Spence's complaint seems superficially plausible, it misses the forest for the trees (no pun intended), focussing on the specifics of the implementations of a yet novel technology and ignoring the momentum that is driving progress forward. It's true that, when you look at a map in Google Maps or on a satnav unit, it, by default, shows you a minimalistic, functional map, consisting of sparse lines rendered in brightly coloured pixels. However, it is also true that there is more than that beneath the surface. Google Earth, Google Maps' big brother, renders the globe with a panoply of user-selectable layers, from the standard geographical landmarks (roads, railways, cities) to links to geotagged Wikipedia pages and photographs (albeit on some weird service nobody uses because everyone's on rival Yahoo!'s Flickr). Google Earth itself allows users to draw their own layers and send links to them. And OpenStreetMap takes it one step further, doing for mapping what Wikipedia did for textual reference works; if you find that your map of Gloucestershire is missing Tewkesbury Abbey or your map of Cental Asia got the Aral Sea wrong, you can correct it. And if you live somewhere where there is no Google Maps (and, indeed, no Ordnance Survey), you can map it yourself (or get some friends together to map it; or petition the local government/chamber of commerce to buy a few GPS units and pay some people to drive around with them, assembling a map). This has resulted in excellent maps of places Google hasn't reached yet, like, say, Reykjavík, Buenos Aires and much of Africa.
Making maps is only half of the equation; it's when one considers what can be done with all the mapping data that things become really exciting. Now that mobile data terminals (which people often still refer to as "phones"), with wireless internet connections and GPS receivers, are becoming commonplace, these soulless, history-levelling map databases are transformed into a living dialogue with and about one's surroundings. Already mobile phones which can help you find various amenities and businesses near where you are are being advertised. It is trivial to imagine this extended from merely telling you where the nearest public toilet is or how to get home from where you are into less mundane matters. Press one button, it points out historical facts about your location, with links to Wikipedia pages; press another one, and it scours online listings and tells you what's happening nearby. Follow any link to flesh out the picture as deeply as you have time for.
Spence's argument reminds me of a lot of the beliefs about computers from the 1950s, when computers were expensive, hulking beasts which were programmed laboriously using punched cards and rudimentary languages like FORTRAN and COBOL. It was too easy to extrapolate the status quo, the baby steps of a new technology, in a straight line and see a future of centralised hegemony and soul-crushing tedium, where the world is reorganised around the needs of these primitive, inflexible machines. Of course, that world never came about, as the machines evolved rapidly; instead of being marshalled into centrally computerised routines, we got iPods, blogs and Nintendo Wiis. To suggest that computerised maps will reduce our shared psychogeography to a collection of colour-coded roads is similarly absurd.
¶ cartography cathedral vs. bazaar geodata geography psychogeography uk 4
For years, map historians have been puzzled by the so-called "London Underground Map", and have speculated on what it could possibly represent. Now a new theory claims that, when rotated and adjusted appropriately, the map corresponds with the map of Australia:
Captain Columbus set sail from Whitby in the "Beagle" soon after he had routed the Armada at Trafalgar, in 1215, and reached Australia a few months later. It is thought that he had the map drawn for him, by one Harry Beck, to remind him where he had buried the treasure. Not wanting the map to lead other explorers to find the loot, should the map have fallen into the wrong hands, he instructed Beck to insert all kinds of fictitious roads and placenames -- even airports!
In Beck's hands, Port Philip is renamed Watford -- presumably in an attempt to deter would-be looters -- Botany Bay is renamed Uxbridge, Perth: Upminster and Albany: Epping. Mystery still remains about the purpose of the zonal markings, but Professor Bovlomov speculates that they might indicate the friendliness -- or hostility -- of the natives. The Professor believes that Beck may have included a coded message within the map to identify the location of the treasure. "Bank" is dismissed as "too obvious", and is probably intended to lead the unauthorised holder of the map to a certain death. West Finchley, though, may prove to be the site of the hidden treasure because, as the professor says: "It is obviously a made up name, and was probably invented by Beck as a kind of joke. No one would ever think of going to such a place, let alone living there!" When asked to comment, other experts said it was Barking.
(via kmusser) ¶ australia cartography geography humour london 0
One of the things that Britain does better than anyone else is postcodes; while most countries' postcodes give you an area the size of a suburb or town, the six or seven letters of a Royal Mail postcode give you a segment of a street, with enough information to find the place the code refers to. This allows sites like the Transport for London Journey Planner to tell you exactly how to get from one postcode to another.
There is a problem with this, though; the postcode data is not free, but is owned by Royal Mail, who monetise the hell out of it. If you wish to use the database for your own purposes, doing so will cost you a few thousand pounds a year. (The fact that your taxes may have paid for the system to be drawn up doesn't enter into the argument.)
Anyway, this has gotten up the nose of a number of open-geodata activists, who are doing something about it: they're collecting their own data mapping points to postcodes, and using this to draw up freely usable and distributable maps of postcode areas. Free The Postcode! is aiming to do this at a high level of accuracy, soliciting input from people with GPS receivers; meanwhile, New Popular Edition Maps is using a 1940s-vintage map of England and Wales (Scotland and Northern Ireland may come later) to allow people to click on where their homes are and enter the postcodes. Since this is inherently less accurate (the map is of fairly low resolution, and the process depends on matching shapes of streets), they're only concerned with the prefixes at this stage. The data produced will be released into the public domain.
(via Boing Boing) ¶ cartography copyfight geodata postcodes uk 0
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Home State Publications II Page 156
Highway work in North Carolina : containing a statistical report of road work during 1911
.138 HIGHWAY WORK IN NORTH CAROLINA.
kiting that the amount voted that year was less than the average, then for
the State to furnish $400,000 it would take probably a $1,000,000 bond vote
from the separate counties. If this would not be sufficient to meet all de-mands,
the amount could be divided pro rata among those counties which had
met the requirements, and the further needs of the counties could be secured
through some other arrangement.
I have consulted some of the best engineers and financiers in the State
regarding this system, and have found all of the engineers consulted enthusi-astic
on the subject. Among the financiers I have found some who have
approached it cautiously, their conservatism being based on their objection to
the State issuing large amounts of bonds; but, when they looked carefully into
the method, they were forced to confess its features are attractive.
A bill providing for the issuance of bonds under this method was introduced
in the last Legislature of North Carolina, was indorsed by the State Highway
Association, was opposed by a special joint committee on roads and highways
of both Houses, was reported favorably by the full committee on highways
and turnpikes, was approved by the committee on appropriations in the Sen-ate,
approved by the House finance committee, passed third reading in the
House by a vote of 87 to 13. and was only prevented from becoming a law by
three majority against it in the Senate. This would seem to be sufficient evi-dence
that there is great merit in the proposition, and that it is one which
will be of great benefit to the State, not only for the present, but future gen-erations.
The following suggested legislation is recommended, which embodies
this idea
SUGGESTED LEGISLATION FOR PROVIDING FUNDS FOR THE CONSTRUCTION
OF PUBLIC HIGHWAYS.
The General AssemMy of Worth Carolina do enact:
Section 1. That for the purpose of assisting the several counties composing
the State of North Carolina in their construction of public roads, the State
Treasurer is hereby authorized and directed to issue bonds of the State of
North Carolina, payable forty years after date of issue of said bonds, which
shall be the first day of July of each year beginning with the first day of
July. 1013, to an amount not to exceed $500,000 annually, and all said bonds
shall bear interest at a rate not exceeding 4 per cent per annum from the
first day of July of the year they are issued until paid, which interest shall
be payable semiannually on the first days of January and July of each and
every year so long as any portion of said bonds shall remain due and unpaid.
Sec 2. That the proceeds received by the State Treasurer from the sale
of the bonds authorized in this act shall be loaned to the several counties of
the State of North Carolina, as hereinafter provided, to be used by said coun-ties
in the construction of macadam, sand-clay, or other surfaced roads as
approved by the Highway Engineer of the Highway Division, if such is estab-lished
by the General Assembly, or by the Highway Engineer of the North
Carolina Geological and Economic Survey.
Sec. 3. That the proceeds from sale of the bonds authorized in this act shall
be allotted to the several counties composing the State of North Carolina in
Title Highway work in North Carolina : containing a statistical report of road work during 1911
Creator Pratt, Joseph Hyde, 1870-1942.
Contributor Berry, H. M. (Harriet Morehead), 1877-1940.
Subjects Roads--North Carolina
Roads--Design and construction--North Carolina
Time Period (1900-1929) North Carolina's industrial revolution and World War One
Description North Carolina Geological Survey, Economic Papers, No. 27
Publisher E.M. Uzzell, State Printers
Agency-Current North Carolina Department of Environmental Quality
Physical Characteristics 145 pages, 7 leaves of plates : illustrations, maps ; 26 cm
Format Periodicals
Digital Characteristics-A 12.6 MB; 166 p.
Series Economic paper (North Carolina Geological Survey) ; no. 27
Pres File Name-M pubs_geo_economic_papers_27.pdf
Pres Local File Path-M \Preservation_content\StatePubs\StatePubs\pubs_geo_economicpapers\images_master\
OCLC Number-Original 3767939
Full Text .138 HIGHWAY WORK IN NORTH CAROLINA. kiting that the amount voted that year was less than the average, then for the State to furnish $400,000 it would take probably a $1,000,000 bond vote from the separate counties. If this would not be sufficient to meet all de-mands, the amount could be divided pro rata among those counties which had met the requirements, and the further needs of the counties could be secured through some other arrangement. I have consulted some of the best engineers and financiers in the State regarding this system, and have found all of the engineers consulted enthusi-astic on the subject. Among the financiers I have found some who have approached it cautiously, their conservatism being based on their objection to the State issuing large amounts of bonds; but, when they looked carefully into the method, they were forced to confess its features are attractive. A bill providing for the issuance of bonds under this method was introduced in the last Legislature of North Carolina, was indorsed by the State Highway Association, was opposed by a special joint committee on roads and highways of both Houses, was reported favorably by the full committee on highways and turnpikes, was approved by the committee on appropriations in the Sen-ate, approved by the House finance committee, passed third reading in the House by a vote of 87 to 13. and was only prevented from becoming a law by three majority against it in the Senate. This would seem to be sufficient evi-dence that there is great merit in the proposition, and that it is one which will be of great benefit to the State, not only for the present, but future gen-erations. The following suggested legislation is recommended, which embodies this idea : SUGGESTED LEGISLATION FOR PROVIDING FUNDS FOR THE CONSTRUCTION OF PUBLIC HIGHWAYS. The General AssemMy of Worth Carolina do enact: Section 1. That for the purpose of assisting the several counties composing the State of North Carolina in their construction of public roads, the State Treasurer is hereby authorized and directed to issue bonds of the State of North Carolina, payable forty years after date of issue of said bonds, which shall be the first day of July of each year beginning with the first day of July. 1013, to an amount not to exceed $500,000 annually, and all said bonds shall bear interest at a rate not exceeding 4 per cent per annum from the first day of July of the year they are issued until paid, which interest shall be payable semiannually on the first days of January and July of each and every year so long as any portion of said bonds shall remain due and unpaid. Sec 2. That the proceeds received by the State Treasurer from the sale of the bonds authorized in this act shall be loaned to the several counties of the State of North Carolina, as hereinafter provided, to be used by said coun-ties in the construction of macadam, sand-clay, or other surfaced roads as approved by the Highway Engineer of the Highway Division, if such is estab-lished by the General Assembly, or by the Highway Engineer of the North Carolina Geological and Economic Survey. Sec. 3. That the proceeds from sale of the bonds authorized in this act shall be allotted to the several counties composing the State of North Carolina in
Highway work in North Carolina : containing a statistical...
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← It’s All Over Now, Baby Blue: Debate #3 Service notice (RESOLVED) →
Politics & Polls #16: The Real Rigged Voting
October 20th, 2016, 11:20am by Sam Wang
Donald Trump has made it clear that if he loses on Nov. 8, it is because the election was “rigged.” He has warned that there might be widespread voter fraud that will favor Democrats. But does this threat have any basis in reality? Or is the real threat new voter identification laws that have the potential to disenfranchise significant portions of the population? Where did these restrictions come from? Julian Zelizer discusses these questions in episode 16 of Politics & Polls with special guest Ari Berman, a senior contributing writer for The Nation magazine. Listen!
P.S. I’m not on this one – scheduling conflict. Julian and I will be together for the next one, in which we talk about the religious right with our colleague Kevin Kruse.
Tags: Princeton
RosiesDad // Oct 20, 2016 at 12:01 pm
Love the podcast, Sam. I binge listened to most of the early ones after I found it (at about Episode 9). Will look forward to hearing you on the next one.
anonymous // Oct 20, 2016 at 12:27 pm
I wonder if the danger of this refusal of Donald Trump to accept the election results gracefully is being overplayed. Is a mature democracy like the US really so fragile as to be dependent on a concession speech?
Greg Gross // Oct 20, 2016 at 12:38 pm
And now The Donald claims that Hillary had last night’s debate questions in advance. What a sore loser….
http://www.nbcnews.com/card/trump-claims-clinton-secretly-used-debate-questions-n670091
bks // Oct 20, 2016 at 1:19 pm
Yup. It’s over when the electoral college votes.
Shawn Huckaby // Oct 20, 2016 at 2:09 pm
Maybe it won’t be a national orgy of overturned cars and pitchfork wielding mobs, but the real danger is further eroding confidence and trust in government among a not inconsequential portion of the populace.
The reason I believe Ryan, McConnell and the rest of Republican leadership is quietly turning a blind eye at this point is that it serves their short-term advantage to have Hillary take office as a weakened and de-legitimized president. They fundamentally don’t care about the long-term health or viability of the republic if it helps them to ride out the next two years with their base. McCain has already let slip the GOP plans to block all of Hillary’s SCOTUS nominees for the next four years. It’s clear that a party concerned about a continued functioning government would not be acting the way they are.
In many ways it’s the corollary to corporations putting all of their focus on short-term investor returns, rather than worrying about the long-term prospects of the company. And we’ve all seen how great that turns out!
Chuck // Oct 20, 2016 at 2:12 pm
It depends entirely on what he says and how his supporters respond. My concern is that many of them act exactly like members of a classic cult of personality. They’re already angry and convinced that they are the victims of a vast conspiracy. Trump has already encouraged them to intimidate voters in “those neighborhoods.” It wouldn’t take much for them to decide to take revenge of the Americans they believe have wronged them by failing to worship their fearless leader.
Our democracy is not that fragile, but civil order can become very fragile if a small number of fanatics decide to start using weapons to express their displeasure.
Taylor // Oct 20, 2016 at 3:27 pm
Our presidential election is not a single election. It’s actually 51 separate elections (the states and DC). If Trump wants to challenge results, he must do it by each state. Polls suggest that Clinton hits 270 just by securing the dark blue states, which will not be subject to recount. Trump could challenge Ohio if it’s close, but it won’t matter. She will still have already beaten him. He may not officially concede, but the GOP will on his behalf. He can sit in Trump Tower and pout.
Ruth Rothschild // Oct 20, 2016 at 6:32 pm
A concession is only a formality and not a requirement. It’s basically the civil and honorable thing for the loser to do in transferring power in a peaceful and honorable manner. Whether or not the loser concedes doesn’t alter the outcome of the election. And, the winner will still be inaugurated in January, 2017, with or without a concession from the loser of the election. What is of more concern is if the loser decides to file a lawsuit contesting the outcome and to demand a recount. That could lead to complications and delays. Hopefully, this election wouldn’t get to that level. Certainly, if Hillary loses, I believe that she would concede.
Of more concern to me is what Sam wrote about voter suppression. And, with the Supreme Court having done away with having voting site monitors from the Dept of Justice present at various voting places, it makes this even dicier, unless there can be a presence of State Dept employees, maybe the National Guard in various locations, and the police as monitors at various sites. But, that isn’t realistic because there probably aren’t enough of those people to go around. My worry also is that many of Trump’s supporters will take up his suggestion to go to voting places and watch to make sure no fraud is happening, but that what will happen, instead, is that these people will intimidate voters who will then step out of line and go home without voting. This sort of thing happened in both 2008 and 2012. It’s a sad commentary on the path this country is going down and the results of polarization.
Rob Honeycutt // Oct 20, 2016 at 7:06 pm
In a way, Hillary actually did have the debate questions in advance…
It’s called “debate prep.”
You prep for all possible questions.
Dave Kliman // Oct 20, 2016 at 1:02 pm
Now it’s time to be the ALEC of the rest of us and use all those grads and post docs to draft boilerplate legislation such as “the fair districting act,” which ought to be presented, on a silver plater, to legislatures across the land, and maybe even federally.
Mike Harrison // Oct 20, 2016 at 5:21 pm
It needs to be federal. At least so it will have effect here in PA. PA is terribly gerrymandered and the legislature would never vote for it. I’m looking at a huge imbalance for Republicans into the unseeable future unless something like this passes.
RonL // Oct 20, 2016 at 11:29 pm
According to reports, this will be one of President Obama’s post-presidential projects… the elimination, as much as is possible, of gerrymandering. But the reports — which indicate a willingness to eliminate all gerrymandering — may not be as accurate as I’d wish. Calling it the National Democratic Redistricting Committee sounds unfortunately partisan. I don’t disagree that a partisan effort on the part of Democrats might level the field. But a nonpartisan effort is more laudable. And admittedly, perhaps has less chance of success… one needs both sides to agree that there is a problem if one takes a nonpartisan approach. I don’t see the current crop of Republican leaders as being willing to admit that there is a problem.
RP // Oct 21, 2016 at 1:17 am
But *why* would GOP leaders admit there’s a problem when gerrymandering helps their position in the House, especially when the 2020 census is around the corner?
The presidency and senate will remain extremely competitive for Democrats unless the GOP does some serious soul-searching (doubtful) and stops pandering to the racists. So widening the moat around the House is a good bet for them, even if it’s through something antidemocratic like gerrymandering.
The GOP is stronger at the *state* level, but as soon as they go national, it’s right into the ol’ brick wall. So gerrymandering is an effective tool to “translate” state-level wins (governorships, legislature majorities) into national ones via the House.
Rachel Findley // Oct 21, 2016 at 10:00 pm
In addition, some of those brilliant and eager incipient academics could work on cases to take through the legal system in the states and to the US Supreme Court, assuming the Senate goes Democratic and the Supremes come to more closely resemble the electorate.
alurin // Oct 23, 2016 at 5:40 pm
A Federal law on redistricting would be unconstitutional; that is entirely the realm of state legislatures. If you want change, you have to do it state-by-state.
No, this is not true. Article 1, Section 4 of the U.S. Constitution states, “The Times, Places and Manner of holding Elections for Senators and Representatives, shall be prescribed in each State by the Legislature thereof; but the Congress may at any time by Law make or alter such Regulations, except as to the Place of Chusing Senators.” An example of federal constraint on redistricting is the Voting Rights Act.
Arthur Neelley // Oct 20, 2016 at 1:26 pm
His not accepting the result on Election Night would only be acceptable IF and only IF it were somehow an extremely close election. All indications are that it isn’t going to be, but I suppose anything is possible.
A // Oct 20, 2016 at 1:31 pm
Read this post if you want your mind refreshed on what a different level Sam has been on compared to..cough…others…when it comes to prediction models in 2015-2016.
http://election.princeton.edu/2016/01/05/what-december-polls-can-tell-us-about-the-gop-nomination/#more-13187
anonymous // Oct 20, 2016 at 2:37 pm
Thanks for pointing out that early post. A good example of clear unbiased thinking leading to a correct prediction.
Matt McIrvin // Oct 20, 2016 at 7:27 pm
Bonus: excellent Sesame Street link.
mcorn // Oct 20, 2016 at 1:50 pm
I don’t think there is any question that the bigger news story with regard to tilting the outcome of elections was and is the unholy alliance of gerrymandering and voter suppression.
The notion that dated voter registration rolls necessarily implies voter fraud has little objective support:
http://www.factcheck.org/2016/10/trumps-bogus-voter-fraud-claims/
deb // Oct 20, 2016 at 3:08 pm
2 things. Since Ds outnumber Rs by 3%, which is a lot, but Rs control the Senate, House, state governorships and state legislatures even in Democratic states, Ds must not be rigging very well.
The suspense after the results, this narcissist, will try and steal the limelight from the first female winner by using that “suspense” to launch his own party and/or media empire. People with NPD can NOT lose face.
Rachel Findley // Oct 20, 2016 at 3:27 pm
Just got to the part of the WOOCast when he says “Trump says he went to college in Pennsylvania, and that’s how he knows the vote is rigged there.”
Can’t resist a nonstatistical aside: decades ago I was a graduate student in Princeton Borough, and I worked as a Democratic Party poll watcher. I noticed two interesting names registered at the Tiger Club on Prospect Street: Seymour Tree and [somebody] Troll. Tiger was famous for a yearly battle between Trees (tall guys) and Trolls (short guys). I flagged them, and they were removed from the rolls. But neither had ever voted. Would that be evidence of voter fraud in Princeton Borough?
Slartibartfast // Oct 20, 2016 at 7:41 pm
Unless they actually voted, that’s voter registration fraud—which has no impact on elections whatsoever.
Rick Howard // Oct 20, 2016 at 9:11 pm
Trump’s National Political Director, Jim Murphy, left the campaign officially today. “I have not resigned but for personal reasons have had to take a step back from the campaign,” he said. Murphy played a key role in setting up field programs in battleground states and is believed to have been a leader for the GOTV effort for Trump.
Phoenix Woman // Oct 21, 2016 at 5:41 pm
“For personal reasons” is the new “to spend time with his/her family”, I take it?
chris // Oct 21, 2016 at 6:19 am
Just a quick question about the EV maps. Today the “distorted to emphasize its share of electoral votes” shows Arizona white, but the undistorted map shows Arizona light blue.
What is the difference in the two maps besides the distortion? A different update schedule, or ??
Keep up the great work.
ravilyn sanders // Oct 21, 2016 at 7:02 am
Eh tu, Dr Wang?
Seriously? Three significant digits? 98.6%? Or is it a sort of inside joke about the normal temperature of human body?
There I was laughing at Nate for giving the third significant digit in the click bait, sorry now cast, prediction.
Lobbying me usually does not work…but you have given me pause.
OK, everyone else…more lobbying. I need to hear more on this topic.
bks // Oct 21, 2016 at 8:54 am
Readers would get the wrong idea if you gave both as 100%.
“>99%”?
Jim // Oct 21, 2016 at 9:08 am
Actually, this is only 2 sig-figs. 1.4% probability of Trump win. Though 2 digits is probably still overdoing it. At this point, the systematic uncertainty is dominant.
The 70% quoted or Senate is the more important probability estimate, although I tend to look more at individual races.
I want as many digits as necessary, significant or not, so that I continue to see progress toward 100%, even if that means the win probability goes to something like 99.994%. Sure it makes no rational sense but according to brain scientist types humans are not fully rational creatures.
@Froggy // Oct 21, 2016 at 9:21 am : I want as many digits as necessary, significant or not…
37 years ago in a freshman physics lab I calculated g, the acceleration due to gravity, to be something like 9.8038383 m/sec^2 using a simple pendulum. The roasting (and the F grade) I got from Dr Swaminathan, may God rest his soul, I will never forget.
If we take delight in what is essentially noise, we might as well consult the tea leaves.
Amitabh Lath // Oct 21, 2016 at 10:23 am
Your site serves a pedagogic function for the math-phobic. I vote for sticking to 2 sig figs, but at this point, the leading “9” is irrelevant.
Why not publish 1-P(Clinton win), in scientific notation if needed?
Or stick to P(Clinton) but give sigma to 2 sig figs.
bks // Oct 21, 2016 at 10:39 am
Convert to the Magic 8-Ball spectrum:
https://en.wikipedia.org/wiki/Magic_8-Ball#Possible_answers
Froggy // Oct 21, 2016 at 11:37 am
@Ravilyn – Thanks for the suggestion in your last sentence. I’m sitting here drinking green tea, listening to “Metal Machine Music,” and loving it.
Slartibartfast // Oct 21, 2016 at 12:50 pm
As I recall, in past years Sam has added extra significant digits when the probability gets above 98%. I think this falls under the same principle as not throwing out polls (like USC/Dornsife) in the middle of the campaign. It’s not clickbait, in my opinion, but valuable information about what the model is saying about the race. It isn’t that an accurate objective assessment of the probabilities, but it is a valid relative measure of the state of the campaign.
If Sam wants to change his policy for next cycle, that’s his prerogative (I would urge him not to), but he should finish out this cycle in the way he finished out previous cycles in my opinion.
Eric // Oct 21, 2016 at 1:06 pm
I vote for >99%. It conveys everything necessary without false precision.
Five Tool Player // Oct 21, 2016 at 2:25 pm
I like three sig figs — not for any mathematical or rational reason — but for reasons of mundane pragmatism. As a college student, I found that college professors almost never took points off of free response test questions if the answer was given with three sig figs. Go Cubs.
Please post also your right-column medians (the Presidential and Senate races) to the closest tent-of-a-percent!
Would you please also add the states where Trump’s median lead has been reduced to single-digit? According to PEC’s spreadsheet this includes:
Texas (–3.5 %)
Alaska (–4 %)
South Carolina (–4 %)
Missouri (–6 %)
Utah (–6 %)
Indiana (–8 %)
“>99%” is fine when the time comes.
Tony Asdourian // Oct 21, 2016 at 5:58 pm
I feel like the whole point of this site is that it isn’t trying to be trendy, just as accurate as possible. If 3 significant figures, in your judgment, conveys meaningful information, I’d keep it. If not, I’d switch over to >98% or >99%.
As an engineer working with real Mr Murphy stuff we don’t buy probabilities with decimal points. Use integers. And 100% defies the universe.
Good work is on display here. This is my thrice daily fix.
Mut // Oct 22, 2016 at 4:45 am
Unhelpfully obvious suggestion: quote a number of digits that reflects the uncertainty on the estimate. If you’re in a binomial-like zone where the error gets smaller as you approach 100%, keep adding digits. If it’s saturated then I’d round to the nearest 1% (or “>99%” if above 99.5%).
Jeremiah // Oct 22, 2016 at 1:04 pm
I have to second Mut’s comment. The number of significant digits has to represent the information from the calculation. The significant digits in this context is not mis-representing the accuracy of the calculation because it has to show the order of magnitude. If Donald Trump had a 0.1% probability of winning then you would have to write that as 99.9% Clinton probability. It doesn’t matter if the accuracy is only +/- 20 % that would give a range of a Trump win of 0.08% to 0.12% which would still be about 99.9% chance of a Clinton win.
The error bar in the probability goes down as the Meta-Margin goes up. This is approximately reflected in the number of significant figures – but not perfectly.
For example, think about the random-drift probability. Imagine that the difference between today’s Meta-Margin and the November 8th outcome is 2% on average. When the Meta-Margin is 0%, if it is uncertain by +/-0.5%, that corresponds to a probability that could be 9 percentage points in either direction from 50%. When the Meta-Margin is 5%, as it is today, the probability will only be off by 0.8 percentage points in either direction. Basically, the probability saturates near 100%.
However, I have found that putting an uncertainty on a probability sounds weird to a lot of people. Instead, I use the significant figures to convey the precision. For the Bayesian prediction, and appropriate statement would be to use whole numbers up to 99%, and above that to say “>99%.” So that’s what we will do.
Matt McIrvin // Oct 21, 2016 at 9:28 am
I’ve been seeing a lot of Democrats in the past couple of days crowing about a wave election, 400+ EV, flipping the House, etc.
I’m seeing little or no evidence of this in polls. Maybe a real wave is coming, but it looks more like a Presidential win for Clinton somewhere in the range between 2012 and 2008 to me, with the Senate up in the air and the House probably out of reach, and we might even be seeing signs of incipient tightening.
I’m thinking there’s just enough time for a spate of “Trump is back!” articles in the waning days before he loses. His loyalists are clinging to the two or three right-leaning polls that frequently show him ahead nationally, and they’ll get very excited when those jump up to what looks like a safe lead, which might contribute to “rigged election” talk on the morning after.
Josh // Oct 21, 2016 at 9:45 am
I agree with much of this. A couple of things to ponder:
1) It’s fairly clear from polling over the last several weeks that most of the support Gary Johnson and Jill Stein are losing is going to Hillary; Trump has been at around 40% since September, while Hillary has gone from 43-44% to about 46%. Concurrently, [Johnson + Stein] has gone from 11-12% to 9%. Even though Johnson supporters’ second choices break fairly evenly for Trump and Clinton, and even though undecideds typically break 50/50, I wonder if this election is different, and that third party supporters and undecideds will break in a larger proportion for Clinton?
2) As has been pointed out elsewhere, Barack Obama ended up over-performing his final polling in each of his two elections (by about 1/2-1% in 2008 and by 2-3% in 2012). Is it possible that Hillary, too, will end up doing better in the final tally than the numbers currently indicate?
3) It’s certainly true that a wave a la 2006 (when Dems won the generic Congressional ballot by something like 15 points) doesn’t seem in the cards this year, but there are still a few weeks for the remaining undecideds and third-party people to go R or D. It wouldn’t surprise me if a combination of polls undervaluing Clinton and a very late rush of support ended up giving her a margin of victory in the 8-10 point range.
Bill // Oct 21, 2016 at 11:04 am
One aspect of gerrymandering is that while creating more winning districts it also reduces the safe margin. This creates a lower threshold for a lot of tipping. I’m hoping Trump supporter despair can help Dems get over that threshold in lots of places.
Ravilyn Sanders // Oct 21, 2016 at 1:02 pm
@Bill // Oct 21, 2016 at 11:04 am
Yes, there were a few posts using the “levee overtopping” analogy. But Dr Wang has calculated the margin of safety built in is around 20% (60-40 splits) in the districts. So we need a larger margin to win. Because house races are polled very rarely he uses a national poll correlation. An 8% generic ballot advantage in national polls is needed to get control of the House. Will that 8% also result in Katrina like levee break up? We don’t know.
Yes. The congressional margin is discouraging. Clinton has very short coat tails. We really need at least two years if House and Senate control to get a reset going. A Republican House will simply obstruct then we have mid-terms that make it worse. An amendment to end gerrymandering can be coupled with the amendment to end the Electoral College.
Michael // Oct 21, 2016 at 11:27 am
Clarification needed for the non-science major:
Is it Hillary’s or Trump’s chances that would correctly be called “asymptotic?”
Douglas Natelson // Oct 21, 2016 at 2:32 pm
Both. Trump’s chances (as estimated here) are asymptotically approaching 0%; Clinton’s are asymptotically approaching 100%.
Olav Grinde // Oct 21, 2016 at 11:45 am
Two new polls from Georgia today showing Trump’s lead reduced to 1 % and 2 % respectively. I do wonder if this is further evidence of a likely wave election.
Historically, apparently only 6 % of voters split their tickets. The question, of course, is how much higher that figure can be in this Year of Trump.
This diagram shows an astonishing shift in early voting margins in swing states – mostly in favor of Democrats.
https://twitter.com/sfcpoll/status/789459176418320384
Surely Trump and his most-rabid supporters will conclude that a 2016 wave is decisive evidence for a rigged election – rather than a massive American rejection of their candidate?
Or, it could just be a concerted effort by Democrats to vote earlier, perhaps in anticipation of trouble on Election Day. I’ve heard anecdotal reports of long lines at early-voting locations in Georgia and NC; many of the people in line are African-American, and keen to evade any vote-suppression schemes that their state governments or Trump supporters might have in store.
Either way, it’s probably a sign of Democratic enthusiasm to get votes counted.
The link to the Louisiana Senate race is broken in the Power of One Vote. A Democrat is currently running 1st but I see there is likely to be a runoff. Is it assumed a Republican will win the runoff in the less crowded field?
It is hard-coded to R+8% until after the runoff is established. No link, sorry.
Via Drew Linzer’s Twitter, about an hour ago.
Surely not impossible, but what are the odds? Maybe 1 in 20, which would be on the order of 80 years. “Dewey” was 68 years ago.
Ariel Edwards-Levy @aedwardslevy
For Donald Trump to win, there’d need to be a bigger polling miss than “Dewey Defeats Truman”
We’re into the realm of two unlikely things at once now: a freakish last-minute collapse of Hillary Clinton’s support and a substantial polling miss.
pechmerle // Oct 21, 2016 at 10:49 pm
The Dewey miss was in an environment with far fewer pollsters in the field. And mostly national popular vote polling, not state by state. So a Dewey-type missing by the polling aggregates is far less likely today than it was in 1948.
Shawn Huckaby // Oct 22, 2016 at 2:37 am
I strongly dislike “maybe”. Data or gut: Pick one.
Bill // Oct 22, 2016 at 6:31 am
Sam Wang and Julian Zelizer discussed Truman/Dewey in an earlier episode. If I remember correctly another factor in the miss was that some of the big pollsters, notably Gallup and the Roper poll, stopped polling weeks before the election and ended up missing the swing to Truman.
Professor Wang, how would we recognise a rigged election? What are the telltale signs – especially in states where the polling might indicate a very close race?
A recount of paper ballots seems straightforward enough, but…
How might the hacking or tampering of voting machines be proven, or for that matter disproven? Can such a suspicion be decisively resolved?
Mind you, I am not wondering specifically about the 2016 Presidential Election, but asking this as a general and principled question.
In the U.S., where polling is mostly high quality, I would look for discrepancies between Election Eve polls and reported results. As far as I can tell, modern elections here have only minor fraud, for example a handful of people voting in the wrong jurisdiction.
Slartibartfast // Oct 23, 2016 at 2:21 am
Thank you Dr. Wang (and Olav for asking the question). I think the best response to everything being done to undermine faith in the elections is to discuss the possible types of polling misses we might see and what they would mean.
The cake is pretty much baked—anyone who has been listening to Sam knows better than to expect the meta-margin to move too much in either direction before election day. The question is how close will the cake be to the one Sam predicts?
While we don’t know what would happen, we can speculate on what various scenarios would look like.
Trump Effect: the sudden surge of silent supporters (or “shy” Trump voters) that will overwhelm Hillary unless the system is “rigged” against them.
pros: Trump said it.
cons: no evidence in primaries, no evidence of increased registration in pro-Trump demographics, no plausible causal mechanism.
magnitude: YYUUGGEE! You’ve never seen a swing this big, it’s gonna be the biggest ever!
how it would look: I would expect this to result in a correlated miss in all states that was strongest in red states and weakest in blue states.
Clinton Effect: A female Bradley effect where voters wont admit they are going to vote to Hillary to pollsters.
pros: there’s research!
cons: motivated reasoning
magnitude: the study shows female gubernatorial and Senate candidates overperform their polling by a little over 2%.
how it would look: this would probably be more pronounced in socially conservative states. A correlated polling miss that was bigger in red states and smaller in blue ones.
GOTV Effect: A game-day effect from widely disparate ground games that isn’t already baked into the polls.
pros: unprecedented difference in Republican and Democratic GOTV efforts.
cons: motivated reasoning.
magnitude: I would be surprised if this was bigger than two or three percent.
how it would look: an effect corollated with the size of the Clinton GOTV effort (normalized by the population of the state).
Clinton “Rigging”: Massive cheating by Hillary.
pros: um… there’s gotta be something, right? Oh yeah, Donald said so .
cons: the data says it isn’t necessary.
magnitude: Since each state’s voting laws and infrastructure is different and each state would have a different amount and possibly type of cheating, the magnitude of this would be somewhat random over a specific group of states.
how it would look: uncorollated misses in specific battleground or near-battleground (pink) states.
Trump “Rigging”: exactly what it says on the tin.
pros: the Republicans do all the cheating they can get away with.
cons: the Trump campaign probably isn’t competent enough to get away with it.
magnitude: probably far too big to go unnoticed.
what it would look like: armed Trump “poll watchers”, violence , and record low turnouts. The end of democracy.
Anyway, that’s just my $0.02.
Matt McIrvin // Oct 23, 2016 at 10:23 am
For a while now, there’s been a strange paper knocking around claiming that the 2008 and 2012 Republican primaries were rigged for McCain and Romney in a huge national conspiracy, and that maybe there was a thumb on the scale for McCain in the 2008 general election as well (though obviously, if so, it wasn’t enough).
The paper makes a statistical argument, that in both cases the establishment Republican candidate got a disproportionately large amount of support from larger precincts, in a way no mechanism other than cheating could explain (it claims to have corrected for urban/rural differences).
The thing that bothers me is, I can’t see any cheating mechanism that could really explain it either. I mean, yes, it stands to reason that if you were going to rig the vote-counting, you’d do it in larger precincts where you get more bang for the buck. But they claim this effect persisted across hundreds of different election systems that used completely different methods, so it can’t be some simple hack to a touchscreen voting machine; it’d have to be some kind of nationwide tampering with centralized tabulators, or something like that. And if you can do that, why would you even focus on specific precincts?
But I haven’t had the opportunity to delve into the original paper in detail and figure out if there’s anything wrong with it. I haven’t seen a detailed debunking, and it’s just out there being mysterious.
Deb // Oct 23, 2016 at 11:07 am
A great example is trump campaign CEO Steve Bannon living in California and DC but registering in Florida at a vacant home once occupied by an ex-wife.
538 Refugee // Oct 23, 2016 at 1:55 am
Excellent read. Actually gives more about Clinton’s agenda than I knew about. Things that the press has ignored because it wasn’t entertaining enough I guess. sigh….
http://www.newyorker.com/magazine/2016/10/31/the-new-yorker-endorses-hillary-clinton
Greg Gross // Oct 23, 2016 at 9:32 am
Excellent article. Its discussion of the Senate leads me to ask a question about the “Senate races” box at the right: Of the 15 races listed, how many have to be Dem wins to gain control of the Senate? I believe it is 4 of these 15 — but I welcome some more expert person’s input on this issue.
Emigre // Oct 23, 2016 at 1:42 pm
@Greg Gross
This is a brief summary of the six seats that could determine the control of the Senate:
http://www.nytimes.com/2016/10/23/us/politics/the-calculus-in-six-crucial-senate-races.html?ref=politics
Greg Gross // Oct 23, 2016 at 3:38 pm
Thanks, Emigre. I hope all the featured Dems win (being a rabid Dem myself).
As to the “Senate races” chart at the right, I believe I have researched and answered my own question in the past 20 minutes or so: The Dems will have to win 6 of the 15 races listed in the chart at the right. The Dems will have to hold the current Dem seats in NV and CO. Plus, the Dems will have to win 4 more seats of the remaining 13 seats shown on the chart.
Currently, Dems are ahead in polls in NH, IN, WI and IL. Those 4 seats are currently held by Repubs. Dem wins in those 4 seats will mean Dem Senate control if Clinton wins, because the VP (Kaine) can break a 50-50 tie on a straight party vote.
Any critiques of the above?
My source for much of this is 270toWin, which states: “Currently, the U.S Senate is controlled by the Republicans. They have 54 Senate seats, Democrats 44, with 2 independents caucusing as Democrats (effectively giving them 46 seats). In 2016, 34 Senate seats are up for election, 10 held by Democrats, 24 by Republicans. Since Democratic Vice-President Joe Biden will break any ties, Democrats must gain at least 4 seats, for a minimum of 50 total, to take control in early January, 2017.”
538 Refugee // Oct 23, 2016 at 11:00 am
It seems Clinton is now making a serious down ticket push.
“Emboldened by polls predicting an electoral-college landslide in the presidential race, Clinton is shifting her strategy to lift up other Democrats coast to coast. She and her party are rushing to capitalize on a turbulent turn in Trump’s candidacy, which has ruptured the Republican Party, to make down-ballot gains that seemed unlikely just a month ago.”
https://www.washingtonpost.com/politics/buoyed-by-rising-polls-clinton-shifts-to-a-new-target-the-house-and-senate/2016/10/22/9c717070-97c3-11e6-bb29-bf2701dbe0a3_story.html
Obama also is getting into the act:
… President Obama called Rep. Darrell Issa (R-Vista) “shameless” for using the president’s photo on a recent mailer and praising him after years of criticizing the Obama administration.
Issa is facing an unexpectedly tough race this year as the eight-term Republican squares off against political novice former Marine Col. Doug Applegate.
“Issa’s primary contribution to the United States Congress has been to obstruct and to waste taxpayer dollars on trumped-up investigations that have led nowhere. And this is now a guy who, because poll numbers are bad, has sent out brochures with my picture on them touting his cooperation on issues with me,” Obama told the crowd, according to a transcript, at a Democratic Congressional Campaign Committee fundraiser in the La Jolla home of donor Christine Forester. “Now that is the definition of chutzpah.”
The Vista Republican has been a frequent critic of Obama and has called him “one of the most corrupt presidents in modern times.” …..
Issa has long been as annoying as the crappy car alarms he used to inflict on the public. His sudden bout of expedient hypocrisy is certainly the definition of something in Yiddish. I’d say he’s a putz who’s afraid of getting schlonged in the election!
Are we back to February yet? ;)
http://election.princeton.edu/2016/05/22/february-national-polls-are-the-best-you-get-until-august/
With this in mind I have been doing a customization of the Pollster graph and keeping tabs that way. Yeah, it might be over smoothed but we are now not much changed in point spread and magnitude.
goo.gl/L2Jidx
Examining the internals of the new ABC poll which finds Clinton up by 12%, TPM noted
“The previous ABC/Post poll found a sharp 12-point decline in enthusiasm for Trump among his supporters, almost exclusively among those who’d preferred a different GOP nominee. Intended participation now has followed: The share of registered Republicans who are likely to vote is down 7 points since mid-October.”
http://talkingpointsmemo.com/edblog/the-internals-of-the-abc-poll-could-be-a-big-deal?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+Talking-Points-Memo+%28Talking+Points+Memo%3A+by+Joshua+Micah+Marshall%29
I saw something at the end of the 3rd debate that reminded me of a fight between my wife’s two cats. The winner went forward to get her prize while the loser hung back licking his wounds. I’ve seen that scenario many times with the cats and it looked EXACTLY the same in many respects. Even leaving the building you could see Trump and supporters were subdued. 3rd debates don’t move the needle? Hillary may not have scored a knockout but Trump received a standing 8 count and hasn’t recovered yet. He’s holding on fighting just to survive. His tone has been more subdued ever since or the news media is biased and just showing us a different Donald. Seriously. His call for down ticket support sounds to me like he is trying to throw the party a bone knowing he has lost the presidency for them.
Politics explained? ;) Not that we needed the science on this to know it was true, but it’s nice to have a backup.
“Your brain gets used to lying as you do it more”
http://www.theverge.com/2016/10/24/13375950/lying-brain-dishonesty-study-learning-to-lie-amygdala
Ed Wittens Cat // Oct 24, 2016 at 9:28 pm
Some brain morphologies are just more permeable to “sticky” falsehoods.
journals.plos.org/plosone/article?id=10.1371/journal.pone.0052970
Rhina // Oct 24, 2016 at 9:13 pm
http://nevo.news/index.php/2016/09/19/latest-presidential-poll-shows-donald-trump-beating-hillary-clinton-in-head-to-head-contest-trump-taking-70-of-the-electoral-votes/
Found this link, and it is funny how different the polls look here. I guess that we are just being fooled. Sam what do you think?
It is unusual to see a post like that: completely false, with made-up statements. The nerve is incredible.
Alex // Oct 26, 2016 at 11:31 am
I was linked to that site on Facebook by an innumerate person “asking questions” about voter fraud. It is a Breitbart.com scraper/aggregator.
Charles Howes // Oct 24, 2016 at 9:15 pm
Do they teach anything about word connotation/denotation and subliminal persuasion in college writing any more? I spent years in Marketing Communications and I could see the bias from the very beginning of this election. Trump is absolutely right, the election is rigged! The only stupidity here is in those who think the rest of us can’t see it!
Charles, you have not provided any support for your assertions. I rather doubt that you can do so, but there are few Trump supporters here. So I will let this comment through in case you have evidence.
Everyone else…note that I prefer comments to contain data and be well thought-out.
Robert Del Medico // Oct 24, 2016 at 10:14 pm
Ah good, an appeal to authority in place of an actual argument. We were overdue for one of those.
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Events Home / Sarge's 14th Annual Dog Walk
Sarge's 14th Annual Dog Walk
Aug 3, 2019 – 9:00 AM - 11:00 AM
Haywood Historic Courthouse
Waynesville, NC 28786 Map
Sarge’s Animal Rescue Foundation will hold its 14th Annual Downtown Dog Walk at 9 a.m. Saturday, Aug. 3, in downtown Waynesville. The fundraiser supports the homeless dogs and cats of Haywood County — and is a much-loved community event, bringing hundreds of dogs and their families to Waynesville’s Main Street.
The start time is at 9 a.m. Aug. 3, to try to beat the heat.
The Downtown Dog Walk scene is a wonderful blend of tail wagging and smiles, as dogs and their humans congregate on the courthouse lawn.
“Sarge’s Annual Dog Walk is a great opportunity for us all to celebrate our canine friends,” said Fred Strohm, Sarge’s administrator. “It’s a wonderful thing to see so many people both passionate about the cause and enjoying the company of dogs."
Participants may pre-register online at www.sargeanimals.org or pick up a form at Sarge’s Adoption Center, The Dog House or Smoky Mountain Dog Bakery, all in Waynesville. Day-of-event registrations begin at 8 a.m. at the courthouse lawn.
“This event is not only a fun time for all — it gives the community an opportunity to be a part of helping with the animals’ medical costs, supplies, food, boarding and fostering,” said Felisha Yon, Sarge’s board member and Dog Walk co-chair. “Join us in celebrating the 10,000 animals Sarge’s has saved during its 13-year history.”
The walk begins and ends at the Historic Haywood County Courthouse on Waynesville’s Main Street. After the walk, there will be contests, with guest judges 99.9 KISS Country personalities Eddie Foxx and Sharon Green. See dogs compete in dog/owner look-a-like, best-dressed dog, best dog trick and best tail-wagging dog.
Attendees will want to visit the pet-related vendor tables before and after the walk.
This year, Sarge’s is offering a simplified pricing structure. For $30 per person, attendees receive admission to the Dog Walk, admission for as many dogs as you want to walk, one T-shirt, a goodie bag provided by sponsors, and an event bandanna for your pup.
The official 2019 Downtown Dog Walk T-shirt will be available for $15 for adults and $10 for children. The T-shirts will also be on sale at pre-registration and at the Dog Walk.
“If you can’t join us that day, or don’t have a dog to walk, you can still help,” Yon said. “Sign up to be a virtual walker. Sponsor a Sarge’s foster dog for $15 and a volunteer will walk a foster dog for you. What a treat for a foster dog to be able to join the fun. He or she might even find their new home.”
Sarge’s Animal Rescue Foundation is at 256 Industrial Park Dr., Waynesville. Visit www.sargeanimals.org, ‘Like’ Sarge’s Facebook page or call 828-246-9050.
$30 to walk dogs
Facebook Event | https://www.sargeanimals.org
Cinnaholic all-vegan bakery
Great Smoky Mountain Food Days
Wild Boar Tavern opens in North Knox
The fans of Def Leppard and Journey
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