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AllAuthorsArticle TitleHeadingsBibliographyWorks Lists and EditionsImage CaptionAbbreviation From 1888199220012002200320042005200620082009201020112012201320142015201620182019 To 1888199220012002200320042005200620082009201020112012201320142015201620182019 Single year 1888199220012002200320042005200620082009201020112012201320142015201620182019 Biographical Article (49) Any Baptism Birth Burial Death Floruit [[missing key: search-facet.tree.open-section]] Peoples and Music Cultures (1) Jewish Music (1) Keyboard Instruments (1) Late 18th c./Classical (1750-1800) (2) 19th c. /Romantic (1800-1900) (23) 20th c. (1900-2000) (24) 21st c. (2000-present) (6) Western Asia, including Middle East (2) Central Europe (12) Russia [Russian Federation] (4) Southeastern Europe (5) Southwestern and South Central Europe (4) The Americas (14) Northern America (11) Collector or Curator (1) Composer or Arranger (49) Critic or Journalist (1) Music Educator (49) Music Manager or Administrator (4) [[missing key: search-facet.tree.open-section]] Performer (49) Conductor (49) Instrumentalist (12) Vocalist (1) Publisher or Editor (2) 1-20 of 49 results for: All: Opera for all x Composer or Arranger x Conductor x Music Educator x Search for "Opera for all" in The Oxford Dictionary of Music and The Oxford Companion to Music Sort by RelevanceTitle - A to ZTitle - Z to AAuthor/Editor - A to ZAuthor/Editor - Z to APublished In Print Date - Oldest FirstPublished In Print Date - Newest FirstPublished Online Date - Oldest FirstPublished Online Date - Newest First Bochmann, Christopher Sérgio Azevedo Gregoriano de Lisboa ( 1980–90 ) and the Escola Superior de Música de Lisboa (from 1985 ), of which he is the present director and head of composition. In 1984 he became conductor of the Portuguese Youth Orchestra. Bochmann has composed a large number of works in almost all genres except opera, and he has written regularly for young musicians and amateurs. Until the 1980s his music used many of the techniques of the avant garde of the 1950s and 1960s; subsequently, contact with musicians without specialist experience of contemporary music has resulted in greater Soliva, Carlo Evasio Zofia Chechlińska tsar’s royal chapel, director of the opera and teacher of music theory and head of singing classes at the school of drama. In 1841 , after a visit to Italy, he settled in Paris. His other compositions were mainly sacred vocal and chamber works. He also wrote a two-volume textbook, Szkoła śpiewu konserwatorium muzycznego w Warszawie (‘School of Singing of the Music Conservatory in Warsaw’). Works Operas all operas performed Milan, Scala, unless otherwise stated La testa di bronzo, ossia La campana solitaria (opera comica, 2, F. Romani), 3 Sept 1816 Vidal, Paul Antonin David Charlton some of Paul Vidal’s works) for wind ensembles. Works all printed works published in Paris Stage all first performed in Paris Eros (fantaisie lyrique, 3, J. Noriac, A. Jaime and M. Bouchor), Bouffes-Parisiens, 22 April 1892, vs (1892) L’amour dans les enfers (1, A. Pigeon) (1892) Guernica (drame lyrique, 3, P. Gailhard and P.B. Gheusi), OC (Lyrique), 7 June 1895, vs (1895) La Burgonde (opéra, 4, E. Bergerat and C. de Sainte-Croix), Opéra, 23 Dec 1898 (1898) Ramsès (drame, 1, L. de Pesquidoux) Stephănescu, George Viorel Cosma taught singing and opera from 1872 until 1904 at the Bucharest Conservatory, where his pupils included Teodorini, Darclée, Nuovina, Giovanni Dimitrescu and many others who were to make international reputations as opera singers. Stephănescu himself was never a professional singer, but he was an outstanding teacher, and he summarized his method in Despre mecanismul vocal (‘On the vocal mechanism’) (Bucharest, 1896 ). He conducted at the Bucharest National Theatre from the foundation of the Romanian Opera in 1877 ; he also helped to further opera in the city by training Ippolitov-Ivanov [Ivanov], Mikhail Mikhaylovich Inna Barsova ‘spring overture’ Yar-khmel′ shows; he was also influenced by Balakirev in his interest in the oriental, displayed in his operas Ruf ′ (‘Ruth’) and Izmena (‘Treachery’) as well as in the well-known suite Kavkazskiye ėskizï (‘Caucasian Sketches’). All that he inherited from Tchaikovsky was an elegance of phrasing and a song-like arioso ; Ippolitov-Ivanov's opera Asya was composed mainly under the influence of Yevgeny Onegin . His last opera Poslednyaya barrikada (‘The Last Barricade’), is set at the time of the Paris Commune. Other notable features of Ippo Bazin, François-Emmanuel-Victor Gérard Streletski Filarmonica Romana while he was at the Villa Medici. When he returned to Paris he soon became highly regarded as a teacher and as a composer. In 1846 his one-act Le trompette de Monsieur le Prince proved to be the first of a series of successful stage works up to 1870 , all performed by the Opéra-Comique. The most popular, judging by the many transcriptions, must have been the three-act Le voyage en Chine , to a libretto by Eugène Labiche ( 1865 ). Vocal music was another of Bazin’s main interests. He composed for and conducted choirs in Paris. He was an enthusiastic Reissiger, Carl Gottlieb John Rutter and Manfred Fensterer as director of the Hofoper in Dresden. As a champion of German opera, he was at first harassed by pro-Italian factions, but his excellent performances of Oberon and Euryanthe won him approval, and in 1828 he was appointed Hofkapellmeister with responsibility for sacred music, chamber music and the music for the court theatre, a post he held until his death. Besides his activities as Kapellmeister, his contract also obliged him to compose a mass annually for no extra fee. The records show that in all he composed 12 Latin masses and a Requiem during his term of office Davïdov, Stepan Ivanovich Geoffrey Norris IRMO A. Rabinovich : Russkaya opera do Glinki [Russian opera before Glinka] (Moscow, 1948) [incl. excerpt from Lesta in fs] P.V. Grachov : ‘S.I. Davïdov’, Ocherki po istorii russkoy muzïki 1790–1825 [Essays on the history of Russian music 1790–1825], ed. M.S. Druskin and Yu.V. Keldïsh (Leningrad, 1956), 263–82 L. Fedorovskaya : Kompozitor Stepan Davïdov (Leningrad, 1977) Yu.V. Keldïsh : ‘S.I. Davïdov’, Istoriya russkoy muzïki , 4 (Moscow, 1986), 145–67 See also from The New Grove Dictionary of Opera : Stepan Ivanovich Davïdov ; Lesta Hernández Moncada, Eduardo Eduardo Contreras Soto but without resorting to specific references. His harmonic construction is chromatic and rhythmically innovative. His Symphony no.1, with its original treatment of rhythm within a classical format, the opera Elena , various songs such as Tres sonetos de sor Juana , and his piano piece Costeña are all noteworthy compositions. Works ( selective list ) Opera Elena (1, F. Zendejas), 1948, Mexico City, Palacio de Bellas Artes, 23 Oct 1948 Ballets Procesional, 1940 Antesala, 1952 Ermesinda, 1952, suite, orch, 1952 Theatre music Bajío, ov. for Wilson, Charles Elaine Keillor Guelph Light Opera and Oratorio Company ( 1955–1974 ), conducted the Bach-Elgar Choir of Hamilton ( 1962–74 ) and was the chorus master of the Canadian Opera Company ( 1973–81 ). In 1979 he was appointed to the faculty of music at the University of Guelph where he later became composer-in-residence and the director of the electronic music studio. He retired in 1994 . Although his early compositions were primarily instrumental, he produced much vocal music later in his career, including an oratorio, The Angels of the Earth ( 1966 ) and a number of operas. Héloise Vaughan Williams, Ralph Hugh Ottaway and Alain Frogley national. A striking innovation is the matching introduction and epilogue. Also used by Bax, the epilogue is Vaughan Williams’s most personal contribution to symphonic form (cf all his symphonies except the Pastoral , where the finale has its own introduction and epilogue, and nos.8 and 9). Although the London was originally to have been a symphonic poem and has been described as ‘a misplaced opera’ – more concretely the composer acknowledged a background link with H.G. Wells’s Tono Bungay – Vaughan Williams rightly insisted that it was ‘self-expressive, and must stand Conte, David M. Dee Wilkins Conservatory of Music. In 2010 he joined the faculty of the European American Musical Alliance in Paris. Conte is frequently commissioned, and among his output are six operas, two film scores and numerous choral works. His first opera, The Dreamers (Philip Littell, librettist), received notice at its 1996 premiere, from which stemmed a commission for The Journey (a cantata, 2001 ). His second opera, The Gift of the Magi , has received numerous productions since its 1997 premiere. Film scores include music for Orozco: Man of Fire ( 2006 ), and Ballets Russes Dopper, Cornelis Theo Muller Symphonia epica based on Homer and the orchestral studies Päân I and II . But above all Dopper was a Dutch composer, as shown by the titles of his Rembrandt , Amsterdam and Zuiderzee Symphonies. In this last work he neatly combines melodies from Valerius’s songbook Nederlandtsche Gedenck-clanck ( 1626 ). Only three of Dopper’s works have been published; his complete works are preserved in the Gemeentemuseum, The Hague. Works ( selective list ) Operas Het blinde meisje van Castel-Cuillé (H.C. Meursinge-Offers), 1892, The Hague, 17 Dec Lipiński, Karol Józef Józef Powroźniak and Zofia Chechlińska he was appointed Konzertmeister by the Saxon king in Dresden. From that time on, all his activities centred on Dresden, where apart from the royal orchestra he formed his own string quartet and taught, among others, Wieniawski and Joachim. In 1861 he retired to his estate at Urłów. One of the best violinists in the first half of the 19th century, Lipiński represented the orthodox Classical school of Viotti and Spohr, with an emphasis on good tone quality. Lipiński’s mastery of all the other elements of technique made his style unique. His compositions include three Mureşianu, Iacob Romeo Ghircoiaşiu and Laura Otilia Vasiliu stage as an opera. His symphonic overture Ştefan cel Mare (‘Stefan the Great’) is one of the first Romanian pieces of programme music. As a forerunner of the school of Romanian piano music, he wrote miniatures in a Romantic style, a rhapsody, and fantasies on folk themes, and many dances collected in different regions of the country. His five vaudevilles and his operetta Millo director , all based on comedies by Vasile Alecsandri, were performed by amateur theatre companies. His choruses and songs for schools, salons, and musical societies were all composed according Molina, Antonio Lucrecia R. Kasilag diploma 1933 ); his composition teacher was Nicanor Abelardo. Later he joined the staff of the University of the Philippines, where he was secretary of the conservatory until 1941 . He taught and lectured outside the university as well, also conducting choral groups, church choirs, opera and orchestral concerts. In 1956 he was made director of the Cosmopolitan Academy of Music, and also directed the Centro Escolar University Conservatory ( 1948–71 ). He received an honorary doctorate from the university in 1953 and was made dean emeritus of the conservatory on his Fano, (Aronne) Guido Alberto Fabio Fano and Roberta Costa MGG1 ( R. Allorto ) A. D’Angeli : ‘L’opera musicale di Guido Alberto Fano’, Cronaca musicale , 13 (1909), 256–60 I. Valetta : ‘Rassegna musicale: i concerti al Corea’, Nuova Antologia , 44 (1909), 331–2 F. Fano : ‘Di una corrispondenza di Guido M. Gatti con Guido Alberto Fano con notizie e considerazioni connesse’, Quadrivium , 14 (1973), 45–64 F. Fano : ‘La figura di Guido Alberto Fano’, Rassegna musicale Curci , 28/2–3 (1975), 41–4 V. Fano : ‘Come far uscire la fanciulla dal pozzo – Vicissitudini di un’opera: Juturna di Guido Alberto Fano ed Ettore Chadwick, George Whitefield Steven Ledbetter and Victor Fell Yellin career commentators noted ‘American’ traits in his music, as in the String Quartet no.2 and the scherzos of his first two symphonies. Some works, such as the lyric drama Judith , show an interest in French sonorities, while The Padrone , for all its evocation of American urban life, draws on the techniques of verismo opera. In the scherzo of the Second Symphony he uses a pentatonic melody resembling black American song nine years before Dvořák included the better-known example in his Symphony no.9 (‘From the New World’). Most movements of Chadwick’s symphony use Mendelsohn, Alfred Viorel Cosma and Ruxandra Arzoiu Lenin’), 1957 , and Pentru marele octombrie (‘For the Great October’), 1960 . His dramatic temperament is evident in the operas Meşterul Manole (‘Master Manole’) and Michelangelo , but even more so in the oratorios Horia and 1907 and in the Symphony no.3 ‘Reconstructia’. The basis of his style evolved from late Romanticism to serialism in the manner of the Second Viennese School and reveals a great mastery of compositional technique in all genres; His final mature manner was realized in several works of a nationalist spirit written between 1950 and 1966 Deldevez, Edmé(-Marie-Ernest) of his teachers, particularly Halévy and Berton. However, it was above all his talents as an orchestrator that were recognized by his contemporaries; Gounod and Berlioz in particular paid tribute to his skill. Works MSS at F-Pn, printed works published in Paris Sacred 3 requiems op.7, 1843 (n.d.) op.28 no.1, 1877 op.28 no.2, 1870 Choeurs religieux, hymnes, op.18 (1847) O salutaris, op.14a, 1847 (n.d.) Prière pour la paix, op.28 no.6 (1870) Dramatic Operas Samson, 1837, lost Lionel Foscari (1), 1841, F-Pn *; Le violon enchanté
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Jobs+ How to search and apply for jobs Students+ Sell your brand Register as a Student Helping you hire Register as an Employer About Page Talent Page Talent for schools Home>Gregory Wealth Management LLP Gregory Wealth Management LLP We are a family run practice with over 30 years’ experience of providing a wide range of advice to private individuals. Our clients range from professionals and business owners, through to entrepreneurs and those now enjoying their retirement. We also work with a number of businesses and organisations from the private and public sector, providing advice, support and business consultancy. We are a friendly team of fourteen personnel and we believe that close working relationships are paramount in building a successful business. We believe that our employees are our biggest asset and will assist with professional growth within the financial industry. Consultancy, Strategy & Change Marketing & Agency Public Sector & Not for Profit Investors site Page Executive Page Talent is part of the PageGroup. Page Talent is a trading name of Michael Page International Recruitment Limited. Registered in England No. 04130921 Registered Office: Page House, 1 Dashwood Lang Road, Addlestone, Weybridge, Surrey, KT15 2QW
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Home Tricity ATM fraudster arrested, duped several of lakhs ATM fraudster arrested, duped several of lakhs Mohali, June 17: The police arrested a member of a gang, involved in ATM frauds in the area, here. The suspect has been identified as Satish, a resident of Alamgirpur, Muzzafarnagar district, Uttar Pradesh. At present, he was putting up in a rental accommodation at Dadu Majra, Chandigarh. Giving information, Mohali Senior Superintendent of Police Harcharan Singh Bhullar said the suspect, along with other members of the gang, had looted lakhs of rupees after exchanging ATM cards of several persons. “The gang had committed more than 50 such frauds in several places, including Chandigarh, Mohali, Ropar, Ambala, Himachal Pradesh, Delhi and Meerut. The gang members usually targeted elderly persons on the pretext of helping them in withdrawing money from ATMs,” said SSP Bhullar. They used to exchange the card of victim with another one and then withdrew money from bank account. SSP Bhullar said another member of the gang, identified as Monu, had already been arrested by the Chandigarh Police. One more member of the gang, Kuldeep Singh, alias Guddu, is already in the custody of the Mohali police. The police have recovered cash worth Rs 25,000, five ATM cards, a Honda Civic car, two gold rings, one gold chain and one silver bangle from Satish. A case under Sections 420, 465, 467, 471, 472, 120-B and Section 66 of the IT Act has been registered against the accused at the State Cyber Crime police station, here. Other gang members Another member of the gang, identified as Monu, has already been arrested by the Chandigarh Police. One more member of the gang, Kuldeep Singh, alias Guddu, is in the custody of the Mohali police. Previous articleKota MP Om Birla to be NDA’s nominee for Lok Sabha Speaker’s post Next articleJodhpur Court acquits Salman Khan in fake affidavit case Dhakoli dacoity cracked, 4 held
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Andy Isabella is much more than a slot receiver, can ‘do it all’ By Austin Gayle College & Draft Featured Tools PFF Mock Draft Our latest 2019 NFL mock draft. Wes Welker, Julian Edelman, future New England Patriot are all classifications tied to 5-foot-9, 186-pound UMass receiver Andy Isabella all because he fits the mold for a successful but limited slot receiver in the NFL. But Isabella is different, and those who confine him into the aforementioned categories are, well, wrong. “I can do it all,” Isabella said in a February interview with Pro Football Focus. “If they want to put me at running back, I can do that. If they want to put me at outside [receiver], I can do that. If they want to put me inside, then I think I showed at the Senior Bowl that I can do that, as well.” Of course, Isabella doesn’t just talk the talk. He has experience at running back dating back to his high school days in Mayfield, Ohio and came to UMass as a running back. It didn’t take long for Minutemen coaches to move Isabella to wide receiver after seeing him dominate at the position on scout team in practice. Fast forward three years after his freshman season and Isabella truly dominated at outside wide receiver in 2018. While playing more than 63% of his offensive snaps outside the hashes at wide receiver, Isabella earned an FBS-high 93.2 overall grade in 2018. Among the 234 FBS receivers with 300-plus routes run in 2018, Isabella ranked first in yards per route run and 17th in passer rating when targeted (129.3). Isolating his play to just the 242 routes Isabella ran at outside receiver this past season, he caught 68-of-97 targets for 1,366 yards (587 YAC), 32 first downs and 12 touchdowns en route to an FBS-high 93.7 receiving grade. No receiver graded out higher than Isabella on the outside, and no receiver averaged more yards per route run; his 5.64 yards per route run average also led the FBS, and the player in second, Missouri’s Emanuel Hall, averaged just 3.57 yards per route run. And his 143.6 passer rating when targeted at outside receiver ranked second. However, despite all of his success on the outside, Isabella said a bulk of the teams he’s already had opportunities to speak with want him to play slot at the next level, making his trip to the Senior Bowl that much more important. “All Senior Bowl week, I was in the slot, and it was frustrating,” Isabella said. “That whole week was almost like an adjustment. But I definitely learned a lot from that week and got better playing in the slot and got kind of used to that role I might have to play. “In the slot, you really have to run precise routes. You can’t really use your speed to get open. So, [the Senior Bowl] really helped me work on my routes that week.” Isabella, despite the slot adjustment, dominated the Senior Bowl. He led the group of 35 senior wideouts with at least 20 offensive snaps in overall grade, catching all seven of his targets for 74 yards, four first downs and a score. But it wasn’t the style of play that took him to new heights at UMass. In Mobile, Isabela gained 74.3% of his yards after the catch and recorded a Senior Bowl-low average depth of target at 2.7 yards beyond the line of scrimmage. Only once in his illustrious 2018 season did Isabella gain more than 60% of his yards after the catch in a single game, and his average depth of target never dipped below 8.4 in any single game, either. His average depth of target for the season (12.5) was also among the top-50 FBS receivers Isabella, a Mayfield track star with legitimate NFL speed, makes his money outside the hashes and down the field. His size might not indicate as such, but his production does. Among the 129 FBS wide receivers with at least 40 targets of 10-plus air yards, Isabella ranked first in receiving grade at 98.0. He also ranked fifth in yards per target (16.5) and 12th in passer rating when targeted (124.3) on such routes, catching 41-of-71 targets for 1,175 yards, 31 first downs and 10 touchdowns. Isabella’s success is rooted in his ability to stretch the field and make the big play, things that can be limited when isolated to the slot in the NFL. The average ADOT for NFL receivers in the slot last season was 9.49; the average ADOT for NFL receivers on the outside was 13.5. Catching 14-of-32 deep targets (20-plus air yards), Isabella recorded the third-most deep receiving yards (705) and nine deep touchdowns. And all 32 targets and 96.5 % of his deep receiving yards came when he was lined up at outside receiver. Isabella wants much of the same in the NFL. “That’s my goal,” Isabella said. “I love watching the big-play guys like Tyreek Hill, Tavon Auston and Odell Beckham Jr… Guys that can just change the game. And that’s my goal. I want to be that player that can just change the game at any moment.” Isabella said he wants to push for an outside role and maintain his big-play ability at the next level but knows he’ll have to earn that opportunity like he did at UMass. And a strong showing and weigh-in at the 2019 NFL Scouting Combine could surely get the ball rolling in that direction come early March.
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Things To Do in Phoenix Here's Your Guide to July Third Friday in Metro Phoenix Circa Survive Are Popping Up in Mesa for a July 27 Performance The Best Free Things to Do in Metro Phoenix This Week Rhett & Link: Live in Concert Phoenix Bands Rock Marquee Theatre at Local Showcase The Best Cafe Review Photos of 2019 July 11 at 11 a.m. Favorite First-Taste Restaurant Photos of 2019 in Greater Phoenix May 16 at 3:43 a.m. Kelli Ward Comments March 21 at 8:31 a.m. Camera footage of the Uber Vehicle Crash March 9 at 7:22 a.m. Air Traffic Control Recordings from Feb. 24, 2018 World-Class Hopi Exhibition Time: 9:30 a.m. - 5:00 p.m. daily Western Spirit: Scottsdale's Museum of the West 3830 N. Marshall Way South Scottsdale http://scottsdalemuseumwest.org Promotional Event Description Canvas of Clay: Hopi Pottery Masterworks from The Allan and Judith Cooke Collection features more than 65 of the finest examples of Hopi pottery, on exhibit for the first time. Spanning six centuries, the exhibition explores the history and stylistic traditions of the Hopi, who have excelled in the creation of ceramics for generations. Among the historic and contemporary masterworks are 18 ceramics by Nampeyo of Hano, the most famous of the Hopi potters. Twenty-two other master potters are also represented in the exhibition, including Nampeyo’s daughters and other descendants. The exhibition includes approximately half of The Allan and Judith Cooke Collection, one of the finest private collections of Hopi pottery, which has been gifted to the museum. Ceramics from the collection will be permanently featured in a new museum gallery, The Allan and Judith Cooke Gallery. Sponsored by the City of Scottsdale, the gallery honors the donor and his late wife, and the Hopi people whose tribal land lies in northern Arizona. A national treasure, this collection serves as a point of pride for the City of Scottsdale and the state of Arizona. Watch the Video Sign up for our weekly guide to events in Phoenix, and never be bored again. With suggestions for every day of the week, our recommendations will keep you busy on any budget. More Promotional Events New Beginnings: An American Story of Romantics and... Paul Calle’s Life of Exploration: From the Mountains to... Dollar Tacos at Devil's Advocate! Wine Tours of Sedona Weekday Happy Hour at Devil's Advocate! Hard Hat Thursdays Thu., Jul. 18 8:00am More Events in South Scottsdale Sink A Hole In One With Star2Star Communications Wed., Jul. 17 7:00pm Billy Bio Fri., Jul. 19 7:00pm
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Unanswered forum topics Show unanswered topics in: Rules & Announcements-Announcements-Website RulesPia Toscano Discussions-Pia Toscano General Discussion-Pia Toscano News & Media Discussion-Pia Toscano Music Discussion-Promoting Pia DiscussionOff-Topic Area-Member Talents Sticky: Pia Paradise FAQ - Frequently Asked Questions by Gary_OC on Friday, February 15, 2013 - 3:26pm 4,241 Website Rules Sticky: Pia Paradise Website Rules and Regulations - PLEASE READ BEFORE POSTING by mshalo18 on Friday, December 7, 2012 - 6:07pm 14,820 Website Rules ‘American Idol’ Finalist Pia Toscano Releases Stunning Rendition Of Shawn Mendes’ ‘In My Blood’ - Hollywood Life by Gary_OC on Friday, July 27, 2018 - 6:30pm 453 Pia Toscano News & Media Discussion Pia Toscano Is Featured This Week On American Idol Icons by Gary_OC on Monday, March 26, 2018 - 4:32am 490 Pia Toscano News & Media Discussion Pia Toscano Interview On Covino & Rich Show on SiriusXM Rush - 4/25/16 by Gary_OC on Monday, April 25, 2016 - 3:22pm 718 Pia Toscano News & Media Discussion Pia Toscano Interview With DJ Hapa on Dash Radio - 4/22/16 by Gary_OC on Saturday, April 23, 2016 - 2:29am 699 Pia Toscano News & Media Discussion Pia Toscano Interview with Kevin and Bean on KROQ Radio - 4/8/16 by Gary_OC on Friday, April 8, 2016 - 3:54pm 649 Pia Toscano News & Media Discussion Pia Toscano Interview With Peter Tilden & Dr. Drew on KABC 790 Talk Radio - 3/23/16 by Gary_OC on Wednesday, March 23, 2016 - 11:30pm 441 Pia Toscano News & Media Discussion Pia Toscano Interview With Dr. Drew on KABC 790 Talk Radio - 3/11/16 by Gary_OC on Friday, March 11, 2016 - 4:39pm 556 Pia Toscano News & Media Discussion American Idol Alum Pia Toscano Competes in Doritos Super Bowl Commercial Contest: Watch the Ad - Billboard by Gary_OC on Tuesday, December 1, 2015 - 6:32pm 574 Pia Toscano News & Media Discussion Watch 'American Idol' Alum Pia Toscano Cover Rihanna, Sam Smith - Billboard 8/25/15 by Gary_OC on Tuesday, August 25, 2015 - 6:06pm 501 Pia Toscano News & Media Discussion 7EAST (Pia Toscano & Jared Lee) to Perform from StageIt Headquarters October 30, 9PM EDT/6PM PDT by mshalo18 on Friday, October 3, 2014 - 5:47pm 5,962 Pia Toscano News & Media Discussion 7EAST (Pia Toscano & Jared Lee) to join Ryan Cabrera, Mark Ballas, We The Kings, Hot Chelle Rae, and more -9/28 3PT/6ET by Gary_OC on Saturday, September 20, 2014 - 7:51pm 1,563 Pia Toscano News & Media Discussion LIVE Dinner & Jam Session with Pia Toscano, Jared Lee and more! #redhour Get your tickets now! by Crissy1121 on Wednesday, August 6, 2014 - 9:27am 821 Pia Toscano News & Media Discussion Glenn Nutley Creates The Perfect Look for Recording Artist Pia Toscano by Gary_OC on Monday, July 7, 2014 - 6:08am 1,036 Pia Toscano News & Media Discussion Pia Toscano To Perform With Jennifer Lopez At Six Concert Appearances This Summer by Gary_OC on Tuesday, May 27, 2014 - 1:49pm 3,180 Pia Toscano News & Media Discussion Pia Toscano To Perform The National Anthem At The Auto Club 400 NASCAR Sprint Cup Series Race on Sunday March 23rd by Gary_OC on Wednesday, March 19, 2014 - 4:42pm 1,014 Pia Toscano News & Media Discussion Live Interview: 'American Idol' star Pia Toscano and Jared Lee to stop at MLive before Lansing Community College concert by Gary_OC on Thursday, March 6, 2014 - 7:04am 923 Pia Toscano News & Media Discussion We're One Year Old Today! Thank You To All Our Members & Visitors by Gary_OC on Sunday, February 16, 2014 - 1:14pm 799 Announcements In Conversation With Pia Toscano by Gary_OC on Friday, January 10, 2014 - 4:47pm 994 Pia Toscano News & Media Discussion
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WHY FRANCHISE PAINT + SIP INDUSTRY THE PINOT DIFFERENCE TOP FRANCHISE FOR WOMEN FEATURED OWNERS IDEAL CANDIDATE DISCOVERY PATH REQUEST INFO! Top Franchise Opportunity For Women Why Is Pinot’s Palette One of the Best Franchises for Women? Pinot’s Palette is in the Top 50 Franchises for Women, as ranked by Franchise Business Review. The list is based on ratings and feedback provided by female franchisees. Female owners make up over 60 percent of the Pinot’s Palette system. We’re thrilled to be ranked so highly by our own franchisees, and to add the rating to our list of awards. Here are a few of the reasons Pinot’s Palette has become one of the top franchise opportunities for women. A Focus on Community Staying engaged in the local community and networking with other organizations is important for franchise owners. These traits are particularly important when it comes to achieving success with Pinot’s Palette’s business model for a couple of reasons. Like a local coffee shop or wine bar, Pinot’s Palette is a social hot spot where area residents can convene to have a fun night out or to host a private party. Community visibility helps drive business. Plus, networking is important for promoting corporate team building events and holiday parties. For many franchise owners, being active in the local community is one of the joys of the job. It builds personal relationships and brings in sales. It also opens up a lot of opportunity for giving back. Most studios hold Painting It Forward events to raise money for local non-profits. They may also give back in other ways, like donating gift certificates for fundraising raffles. Naturally friendly and social, Diana Chams took a great approach to networking before she opened her studio in Brick, New Jersey. As soon as she selected a location for buildout, she got to work networking. She spent the months leading up to her grand opening getting to know neighboring businesses and getting involved in local chambers. By the time her studio opened its doors, she had built rapport with local organizations and consumers. Good Work/Life Balance A flexible schedule and work/life balance bring a lot of entrepreneurs to franchising. Pinot’s Palette offers independence and personal management, along with an established business model and plenty of support. The combination is great for people seeking freedom from more traditional jobs. Leslie Warren left her career as a dental office manager because she needed to find a way to be more available to her family. After opening her own franchise in Livermore, California, she no longer needs a nanny for her children. “I work just as much if not more,” Leslie says, “But my flexibility has changed. I work my schedule around their schedule so I can help with homework and take them for ice cream after school.” Sonja Kapoun-Roof wanted to be part of a company whose culture and values she could respect. After doing her research and interviewing with the Pinot’s Palette headquarters team, she said, “It seemed like a natural fit. I respected their mission and it felt like it matched what I would want to be involved with.” Pinot’s Palette prides itself on operating with integrity, which includes giving back and respecting and supporting artists. As a company, one of the core values is “have fun.” Pinot’s Palette is a fun business to own! The Right Franchise Opportunity for You If you’re a social entrepreneur who enjoys wine, art and entertaining, Pinot’s Palette paint and sip franchise is the perfect concept for you. To find out if we’re the right fit for you, contact us for more information. We can’t wait to talk to you! Submit the following information to learn more about our franchise opportunities and speak to our development team directly. Interested State * Please ChooseAlabamaAlaskaArizonaArkansasCaliforniaCanadaColoradoConnecticutDelawareFloridaGeorgiaGuamHawaiiIdahoIllinoisIndianaIowaKansasKentuckyLouisianaMaineMarylandMassachusettsMichiganMinnesotaMississippiMissouriMontanaNebraskaNevadaNew HampshireNew JerseyNew MexicoNew YorkNorth CarolinaNorth DakotaOhioOklahomaOregonPennsylvaniaPuerto RicoRhode IslandSouth CarolinaSouth DakotaTennesseeTexasUtahVermontVirginiaWashingtonWest VirginiaWisconsinWyoming Interested City * How did you hear about our franchise opportunity? ---Choose One---BizBuySellEmail NewsletterEntrepreneur MagazineEntrepreneur OnlineFacebookFranchise Business ReviewFranchise GradeFriendInc.LinkedInNews StoryPinot’s Palette WebsitePinot’s Palette AppPinot’s Palette LocationPinterestReferralSearch ResultTwitterYouTubeOther FacebookTwitterPinterestYoutubeInstagramLinkedinVimeo Disclaimer and Pre-Disclosure Disclaimer: Information made available through this web site regarding the Pinot’s Palette franchise opportunity is for general information only and is not intended to be a franchise offer. Offers are made only after delivery of an effective Franchise Disclosure Document in compliance with applicable federal and state laws. None of the communications made through this web site should be construed as an offer to sell any Pinot’s Palette franchises in, nor is any such communication directed to the residents of, any jurisdiction requiring registration of the franchise before it is offered and sold in that jurisdiction. No Pinot’s Palette franchises will be sold to any resident of such jurisdiction until the offering has been exempted from the requirements of, or duly registered in and declared effective by, such jurisdiction and the required Franchise Disclosure Document has been delivered to the prospective franchisee before the sale in compliance with applicable law. Pre-Disclosure: Assuming you qualify as a Pinot’s Palette prospective franchisee, we may provide you with a Franchise Disclosure Document in hard copy or electronic format. If the Franchise Disclosure Document is furnished electronically, it will be provided in a Portable Document Format (PDF) file. You must use the Adobe Acrobat program in order to open and view this type of electronic file. Application for Consideration Address: 10333 Harwin Drive Suite #265 Mon - Friday / 8:00 AM - 4:30 PM (CST) © Copyright 2019. Pinot's Palette All Rights Reserved. Pinot's Palette Franchise
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Upcoming PS4 games Xbox Games Pass Upcoming PC games Best Switch games Nintendo game reviews Mario Kart - Nintendo Wii - First Look Stuart Miles | 20 March 2008 23 best Nintendo Switch games every gamer should own Price when reviewed: £40 Quick verdict It's a classic game that Nintendo wisely hasn't really messed with meaning the winning formula is still there Read full verdict Wii Wheel Good fun Internet play Plenty of racescourses Wii Wheel isn't really needed More of the same just a new format A year after its first unveiling and 16 years since it first hit our TV screens, Mario with his go-karting escapades is back, but has it been worth the wait? We don our racing gloves to find out. If you're a fan of Mario Kart, you're going to feel right at home with Mario Kart for the Wii. The concept is the same, i.e., you drive Mario and his mates around a series of racecourses avoiding banana skins and turtle shells in your quest to become crowned the best driver in town. It's not a direct port of the previous iterations and new to the mix are a number of new courses (16 in total) and features such as getting inked by a squid so you can't see what you are doing. However, the most notable of which is the addition of a bit of plastic in the box called the Wii Wheel. The Wii Wheel, which is really just a glorified piece of plastic that you plonk the Wii Remote into, is designed to make it easier to visualise yourself driving and on the whole in our brief First Look play it seems to work. All the Wii Controls on the front of the controller are easily accessible as before and the B button on the back gets a trigger cover, which makes it easier to use when in the landscape mode. In-game and the wheel gives you a greater sensation that you are driving a car and we found that you don't have to be as forceful with your movements to get a reaction on screen. The only drawback is that you do look a bit of an idiot using it, but then anyone who has fished in Zelda knows how that feels anyway. Of course the Wii Wheel isn't a requirement and you can race against up to four other players, either on a course or just as the original, in battle mode popping balloons with standard controllers sans the Wii Wheel. In fact you can even use a GabeCube controller if you've still got one of those kicking around. So that's how you control it, what about the gameplay? Well it's business as usual with 32 courses to race around broken down into a number of different Cups like the Mushroom cup. Win the first batch of cups and you unlock more courses, more characters and more features. Beyond the courses there are the karts and now bikes to choose and race. Again this is broken down into three categories to ease new gamers in. Mario Karters get 50cc, 100cc and 150cc vehicles and within these classes you get different cars and bike that offer different handling characteristics. When racing the bikes are more agile with the ability to perform wheelies and get speed boosts by jerking the Wii Wheel back quickly, however the karts are more stable when it comes to taking knocks from your competitors. Of course the Wii has always been about multiplayer and here you can opt to play on the same screen with up to four players or up to 11 via Nintendo WFC over the Internet. We weren't however able to test playing online in our First Look at the Nintendo Wii house in London. In addition to all this a new Wii Channel, the Mario Kart Channel, is also included offering you the chance to see how you perform against against others with data compiled from races completed online as well as also access and share Ghost Data. However, like the online racing mode we weren't however able to test playing online in our First Look at the Nintendo Wii house in London. If you were a fan of Mario Kart on the SNES or GameCube, then this is more of the same, but a chance to play it on the Wii with the added bonus of the Wii Wheel and the motion sensor shenanigans that go with it. It's a classic game that Nintendo wisely hasn't really messed with meaning the winning formula is still there. A must for the console when it comes out on the 11 April? Judging from our first glimpse, you bet. Sections Nintendo Games PopularIn Games Nintendo Switch Lite: Release date, price, pre-orders and everything you need to know All the PC games in the Prime Day sale that are actually worth buying Best PC gaming gear deals for Amazon Prime Day 2019: Savings on keyboards, headsets and more Best Xbox One deals for Amazon Prime Day 2019: Games, accessories and more on day 2 Best Nintendo Switch deals for Amazon Prime Day 2019: Console bundles, games, accessories and more Best PS4 deals for Amazon Prime Day 2019: Consoles, PSVR, games on day 2
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Energy Secretary Rick Perry and major coal companies pushed against President Donald Trump's nomination of David Hill for Federal Energy Regulatory Commission. | Mandel Ngan/AFP/Getty Images Coal companies join with Rick Perry to derail Trump nominee David Hill, a former Energy Department counsel, had criticized the Trump administration’s push to offer financial help to coal power plants. By DARIUS DIXON The White House has dropped plans to nominate a veteran lawyer to serve on a key federal energy panel after pressure from Energy Secretary Rick Perry and major coal companies headed by allies of President Donald Trump, two people familiar with the effort told POLITICO. POLITICO reported last month that David Hill, who served as the Energy Department's general counsel under President George W. Bush, was the likely candidate for a seat on the Federal Energy Regulatory Commission. A senior administration official said at the time that Hill was "almost certain" to be tapped. But Perry and other senior DOE officials opposed giving the post to Hill, who had publicly criticized the Trump administration's push to offer financial aid to coal power plants — and they were joined in the effort by Joe Craft's Alliance Resource Partners and Bob Murray's Murray Energy Corp., the sources said. Both coal companies are major GOP donors, and Trump has said he planned to nominate Craft's wife, Kelly Knight Craft, to be the U.S. ambassador to the United Nations. When reached by POLITICO on Tuesday, Hill acknowledged that the White House informed him last week that his nomination process had been terminated. Morning Energy newsletter The source for energy and environment news — weekday mornings, in your inbox. He had been expected to fill the vacancy created by former FERC Chairman Kevin McIntyre's death in January. But the parallel efforts by Perry and the coal industry proved to be more persuasive with Trump than his chief economic adviser, Larry Kudlow, who was lobbying for Hill. FERC, an independent agency headed by a five-person board, oversees much of the nation’s electric grid as well as regional power markets. It has become a significant player in the debate about the Trump administration’s efforts to secure coal’s place in the U.S. power supply despite withering competition from alternatives like natural gas and wind. A Republican, Hill worked as a DOE deputy general counsel for three years before becoming the agency’s top lawyer. And like several other Bush energy officials, Hill openly criticized a DOE proposal to FERC that was aimed at propping up money-losing coal and nuclear power plants, calling it "absolutely not the solution" to fix the electricity markets. Hundreds of coal-fired power plants have closed in recent years. Both Craft and Murray have pressed the Trump administration to support the industry, which has seen its share of the nation's electricity generation plunge from more than 50 percent a decade ago to less than 30 percent last year. Trump taps former Delta pilot to lead FAA amid turmoil By BRIANNA GURCIULLO Both Murray Energy and Alliance Resources have big stakes in whether FERC creates market supports for coal, a move the agency has so far resisted amid its effort to determine the resilience of the nation's power grid. Craft has donated millions of dollars to a wide range of GOP campaigns for years. Murrayalso is a staunch Trump supporter and significant GOP donor, and he met with Perry in 2017 to deliver a list of policy priorities that would benefit the coal industry. He blasted FERC last year after the commissioners unanimously rejected Perry’s plan. In 2017, Murray pressed White House officials to help the coal industry, laying out in letters how Trump has instructed Perry to invoke emergency powers under the Federal Power Act to keep power plants operating. A senior administration official this week told POLITICO that "influential detractors" leaped into action to derail Hill, but the person declined to pin the move on Craft and Murray. Murray said Tuesday that he was unaware of anything related to Hill's nomination. "I have no knowledge regarding your inquiry. Thank you," he wrote in a note to POLITICO. Lawsuit accusing Trump of violating Constitution gets hostile reception By JOSH GERSTEIN DOE referred questions on Hill's nomination to the White House. However, the White House declined to comment, and a spokesman for Alliance Resources did not respond to requests for comment. A person familiar with the matter confirmed that senior DOE leaders have been consulted by the White House during the ongoing nomination process and that they met with Hill and other candidates. A White House annual economic report released Tuesday again floated the idea of creating a carve-out to help coal and nuclear power plants. Perry’s plan that FERC rejected early last year isn't the only failed effort to help coal plants. The White House also shelved the more aggressive DOE plan — pushed by Murray — to invoke an emergency to force power companies to keep what it called "fuel-secure" generators like coal and nuclear plants open. Rejecting Hill without having another candidate clear the FBI background check would suggest that a new nominee is probably at least three months away. However, a handful of other candidates have been under consideration at the White House: former Texas utility, oil and gas industry regulator Barry Smitherman; former Wisconsin utility commissioner Ellen Nowak; and Pat McCormick, a former aide to Sen. Lisa Murkowski (R-Alaska). Andrew Restuccia contributed to this report.
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Teenage girls in southern Malawi reject ‘sexual cleansing’ September 29, 2014 • Daily Email Recap Local organisations are helping girls speak out so communities can abandon child marriage and other harmful practices See: http://www.theguardian.com/global-development-professionals-network/2014/sep/18/end-child-marriage-malawi-girls?CMP=twt_gu Memory Banda beat the odds. In Malawi, five out of every 10 girls marry before the age of 18. Her sister married aged 11, but Banda vowed to finish school. When girls in her village were subjected to sexual initiation, Banda organised literacy classes to teach them how to read. Growing up in rural Malawi as the eldest of six siblings, Banda remembers hearing about kusasa fumbi, the traditional practice of sexual cleansing common in southern Malawi. This initiation practice forces young girls to have sex with an older man to cleanse their “childhood dust” and prepare them for adulthood. Known as the “hyena”, this man travels between villages, paid by the community to have sex with girls as young as nine, often exposing them to unwanted pregnancy and HIV infection. This socially sanctioned form of gender-based violence violates girls’ basic human rights, and has devastating repercussions. “Malawi has one of the highest rates of maternal mortality in the world and 10% of the population is HIV-positive,” said Dr Howard Kasiya, health expert and director of the Adolescent Girls’ Advocacy Network of Malawi. “Being forced to undergo kusasa fumbi is often a death sentence for girls.”
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Match Officials: Notts County Port Vale face Notts County in Sky Bet League Two action this weekend as both teams will be looking to climb the table and away from the relegation zone, and the match officials for the league clash have now been confirmed. Craig Hicks has been selected to officiate this weekend's clash, having already taken charge of 31 games so far this season. You can find a breakdown of these games, below. 12 League One games. 10 League Two games. 5 Football League Trophy games. 3 English FA Cup games. 1 EFL Cup game. Over the course of these 31 fixtures, Hicks handed out 101 yellow cards and five reds. He is yet to take charge of a Port Vale game so far this season. Gareth Mellor and Matthew Parry will work alongside Hicks as assistant referees, as well as Joe Clark as fourth official.
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Food and Drink Dec 6, 2018 Hit the Spot’s Program to Help Portlanders in Need by Chad Walsh Allison Kerek Food cart owner Jeremy Sivers is no stranger to need. The Portland native and his brother were raised by a single mother who worked shifts at Mike’s Drive-In in Milwauki and the chainsaw company Blount to make ends meet. When he was five, his family lost everything of value when their home was robbed. They survived much of his childhood by relying on their Oregon Trail card and receiving boxes of foods and clothes delivered to their home. Helping those in need by donating non-perishable canned goods and winter coats to struggling families is always a generous gesture. However, from a kid’s perspective, generosity can sometimes create small traumas when they’re expected to feel gratitude for eating canned foods they don’t like or button up a coat they’d never choose to wear. Sivers wants to turn that kind of charity inside-out at his still fairly new Hollywood neighborhood cheeseburger cart, Hit the Spot. When he opened in late September, he initiated a program offering 10 percent discounts to Portlanders serving their communities: Teachers get the discount on Mondays, single parents on Wednesdays, and active military personnel and veterans get it every day. Meg Nanna But Sivers also aims to offer a more immediate and intimate helping hand. He wants to gift struggling Portland families with what they specifically need, not just what they could merely use. “It sucks growing up poor and struggling, but you sure as hell learn a lot,” Sivers says. “When something terrible happens and you don’t have any money, you can’t really go to the bank to get a loan. There’s really nowhere to go.” To lend that kind of hand, Sivers’ Hit the Spot has launched a public assistance program. Individuals or families can visit the cart’s website to explain the circumstances that have left them temporarily economically vulnerable. If chosen (by resident voters via social media), Hit the Spot will donate 10 percent of its daily sales to the applicant until their assistance is met. Sivers says that kind of relief could take weeks or even six months, depending on what the applicants need. And the assistance can be for any reason: Perhaps a family can’t afford a new winter coat for their kid. Perhaps a family’s breadwinner needs a new alternator so they can get to work on time. Or perhaps an individual needs a serious medical procedure. All are encouraged to apply, Sivers says, no matter the need. Sivers also wants to provide this type of assistance without breaking your bank. Despite providing discounts for teachers, single parents, and more, he still wants to make sure the rest of us can get in and out without ever having to pay more than $10 for an expertly built classic burger, crinkle-cut fries, and a soft drink. “I want people to come here and get a good burger and also know that they’re helping someone who needs it,” Sivers says. So who needs it? So far, Sivers says that no one’s applied to the cart’s assistance program yet, mainly because Sivers has been working so many hours—12-hour days, six days a week—that he’s scarcely had time to promote his cause. But now that you know, he expects all that to change very, very soon. Hit the Spot 4615 NE Sandy, Portland, Oregon 97213 How Portland’s Brazilian Community Saved Brazilian House by Suzette Smith Powell Street Station: Strip Mall of America by Heather Arndt Anderson Tiffin Asha: South Indian Food Built on Passion and Justice by Thomas Ross New Seasons presents The Portland Mercury's Burger Week at Various Locations Sat Aug 17, 10 am & Sun Aug 18, 10 am Portland Hot Sauce Expo at Oregon Museum of Science and Industry (OMSI) July 8–Sept 8 The Portland Mercury's Summer of Slushies 2019 at Various Locations June 2–Nov 24, Sundays, 11:30 am, 1 pm Recovery at the Red Drag Brunch at Radisson RED Last Sundays, 11 am Portland Flea + Food at Portland Flea + Food
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Correction: PPB Arrests Carjacking Suspect-Vehicle Recovered (Photo) Bay.png The suspect from this incident has been identified as 25-year-old Robin Sanford Bay, not George Sanford Bay. Robbery Detective Hiedi Housley is the primary investigator. If anyone has information about either of these cases, she can be contacted at (503) 823-1063. Detective Housley is still interested in hearing from the victim of the second incident. ###ORIGINAL MESSAGE BELOW### On Tuesday, March 19, 2019, at 11:38 a.m., a male was in his vehicle at the Burgerville drive-through at Southeast 12th Avenue and Southeast Hawthorne Street when another male approached him and threatened him. The suspect demanded the victim's vehicle upon threat of injury with a bottle. The suspect drove off in the victim's vehicle, a green Ford Ranger. The victim was not injured. At about 12:02 p.m., a call came into dispatch about a truck that was blocking the driveway near the 600 block of Southeast Cesar Chavez Boulevard. The truck was the same one taken in the earlier robbery. While officers checked the area, they were flagged down by a witness who reported a pedestrian had just been robbed of their cell phone by a male suspect, whose description matched the previous robber's description. The victim of the robbery of the cell phone has not reported this to the police at this time. Officers located the suspect in the 4400 block of Northeast Glisan Street and arrested him. The suspect's identity is still unknown and he is being booked under "John Doe" at the Multnomah County Detention Center on charges of Robbery I and Unlawful Use of a Motor Vehicle. Robbery Detective Hiedi Housley is the primary investigator. If anyone has information about either of these cases, she can be contacted at (503) 823-1063 or at hiedi.housley@portlandoregon.gov . Detective Housley is interested in hearing from the victim of the second incident.
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Biker Chix mountain bike camp offers technique, support By Mark Davis Jessica Lum decided it was time to get on her bike and ride. No more excuses. Lum, a Powell resident and employee at Heritage Health Center, had occasionally joined a group of area women on their … Attention readers The Powell Tribune has expanded its online content. To continue reading, you will need to either log in to your subscriber account, or purchase a subscription. If you are a current print subscriber, you can set up a free web account by clicking here. If you already have a web account, but need to reset it, you can do so by clicking here. If you would like to purchase a subscription click here. Professional mountain bike instructor Gretchen Reuning leads a group of students through a cornering seminar during the Biker Chix mountain bike camp at Beck Lake Bike Park in Cody on Saturday. The three-day camp — the Park County Pedalers’ first at the new park — sold out. Tribune photo by Mark Davis Professional mountain bike instructor Gretchen Reuning leads a group through a cornering seminar before using the pump track at the Beck Lake Bike Park in Cody Saturday. Thirty women attended the sold-out event. Sloan Allen rides the pump track at the Beck Lake Bike Park during a riding technique seminar. Posted Tuesday, July 10, 2018 8:10 am Park County Pedalers’ weekly rides facebook.com/BeckLakeBikePark Lum, a Powell resident and employee at Heritage Health Center, had occasionally joined a group of area women on their Wednesday night rides after moving to Powell from Arizona. “I found excuses not to go. But every time I did I felt great,” Lum said. This year, she pledged to get serious. So when tickets became available to go to a female-only riding camp — the first of its kind in Park County — Lum pulled the trigger quickly. She was one of the lucky riders to score a ticket: The Cody camp sold out in a matter of days. Female-only riding camps have been trending across the nation as the sport grows in popularity. But while the camp is new, women riders in northwest Wyoming have been meeting for more than two decades for rides sans the testosterone typical of the sport. For 22 years, the Biker Chix have left their boyfriends and husbands behind, tearing down trails on mountain bikes and testing their mettle in the dirt. The group is growing along with area mountain bike trail systems. Following the popularity camps in Colorado and southern portions of Wyoming, the Biker Chix decided to bring in pros for a three-day riding skills camp. Along for the ride since day one of the Biker Chix, Rene Huge finds it comforting to learn the sport with her friends. “Women feel more confident to learn with other women. It’s a safe environment. You don’t feel pressure to keep up with your boyfriend or husband,” Huge said. “The whole idea is to get ladies on bikes, show them around and if they want to learn skills we’ll share.” All levels of riders are welcome on the Wednesday night rides. “No rider will be left behind,” Huge said. Thirty riders took part in the weekend training. Moving between several stages — from cornering and braking seminars to customizing bikes to fit each rider — the camp served up technical confidence on trails between laughter and comaraderie. “It’s empowering,” said Gretchen Reuning, a professional trainer from Fort Collins. “They crushed it. They’re getting excited about learning.” All proceeds from the camp go to Park County Pedalers projects and maintenance. The construction of the Beck Lake Bike Park — a project undertaken by the volunteers with the Park County Pedalers — has made a big difference in attracting new riders to the sport, Huge said. “[The park] makes it much easier to get people out and ride,” she said. “It’s nice for us locals to learn here on our own trails, building our confidence to get after it.” Built for different levels of difficulty, the park is fun for riders from beginners to hardcore riders. The project took nearly 10 years to finish and was professionally designed. The park has 10 miles of single track, a pump track and three massive jump lines that include ramps and drops as large as 6 feet. It cost about $350,000 to construct — all raised by local pedalers. “Park County Pedalers have done a fantastic job putting together the bike park. I’ve never ridden anything like it,” said Adriana Arismendi, a Cody rider new to the sport. The park has also attracted a lot of young riders to the sport, Huge said. And it may come in handy as a training mecca for Park County’s first high school club team. High school mountain bike teams have already been organized in school systems, including Cheyenne, Casper and Laramie. A Park County team, still in the planning stages at Cody High School, according to Jen Hess of Casper, would be the first in northwest Wyoming and would bring racing to area single-track courses. Teams would be part of the National Interscholastic Cycling Association, which has been growing rapidly seeing teams from several surrounding states, including Colorado and Nebraska, begin high school leagues. There were several obstacles for the campers, including high heat, mechanical breakdowns on the trail and a few accidents. “There were plenty of crashes. It tends to go with the sport,” Huge said. But organizers are already looking forward to next year’s camp. The popularity of the camp may mean the club will think of bringing on a few more coaches to accommodate more participants. “It’s a fine line. Part of what makes the camp so great is you’re in small group sizes,” Huge said. The next big race may be to get tickets for next year’s camp.
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LCA Metrics/ Column Protecting the value of financial investments with sustainability assessments Now even the Dutch central bank clearly reports* that climate change, water stress, raw material scarcity, biodiversity loss and human rights controversies present risks to the financial sector, institutional investors worldwide are looking for ways to safeguard the value of their investments through sustainability analyses. But how can you do that? Highlights of developments in impact assessment in 2018 Developers of new impact assessment methodologies are constantly on a quest to improve the reliability of LCA results. As a busy LCA practitioner, you may not have the time to keep track of ongoing research. To make it easier for you to get a sense of what is happening in the field, PRé has decided to start doing a bi-annual overview of the most interesting developments. This article was written by Laura Golsteijn with contributions from Peter Fantke, Francesca Verones, Marisa Vieira, and Rosalie van Zelm. Mitigating climate change towards disaster risk reduction Climate change is often linked with long-term effects, such as: polar caps melting, disasters and rising sea level. This week, the Global platform for Disaster Risk Reduction is being hosted in Mexico, where countries will look at the progress made within the Sendai framework agreements. But how can the SDG agreements complement and help prevent disasters? We looked at SDG 13: Climate action, and how sustainability practitioners can help companies take action against climate change; using LCA metrics and indicators. The business benefits of including water footprinting in your environmental KPIs A water footprint is a measure of how much water your business uses and which direct and indirect environmental impacts result from this. It can help you understand and manage your water use and even protect your company from physical, regulatory and reputation risks, adding a valuable and actionable dimension to your environmental KPIs. Sustainability in 2017- Are We at a Tipping Point to Become Mainstream? As we are nearing the end of the year, we’d like to reflect on how sustainability initiatives have progressed in 2016. What is the state of the art in sustainability for business? And what can we look forward to in sustainability in 2017? The cost of fraud: health consequences of fraudulent emissions tests INTERVIEW | At the end of 2015, it became known that Volkswagen Group has been cheating with emission tests for diesel engines over the last six years, resulting in on-road emissions vastly exceeding the legal standards for nitrogen oxides in Europe and the United States. PRé’s Laura Golsteijn interviewed Rik Oldenkamp, one of the researchers who quantified the public health consequences of this fraud. Biodiversity, part 3: biodiversity, climate change and a final question In our biodiversity series, we look at how to assess the impact of biodiversity changes. We looked at the basic assumptions and metrics in Part 1, and in Part 2 we looked at land use change and how that ties to biodiversity. In this article, we discuss the effect of climate change on biodiversity, and pose our final question. The EN 15804 building product LCA standard: more challenges than benefits GUEST POST | In general, the development of standards is a good thing, especially in such a complex environment as building and construction. But not all standards are an unmitigated benefit. This week, we feature a guest post by PhD student Sahar Mirzaie, about her research into the pitfalls and challenges in LCA for the building sector, including the EN 15804 standard. Biodiversity, part 2: land use and biodiversity In our biodiversity series, we address biodiversity and its impact assessment. In part 1, we discussed some definitions and units. In this article, we look at land use and how land use and land-use change affect biodiversity. How do we measure the damage, and who pays? Energy & Transport Data for PEF/OEF Studies: The First Building Block To ensure comparability within products groups, the PEF initiative is facilitating the use of life cycle inventory data. The Energy and Transport data constitutes the first data lot. This is a short update on the availability of this first building block towards consistent EF-compliant data. 3D printing guarantees efficiency. Myth or not? As a science-based method, LCA is an excellent tool to bust the myths that surround sustainability. In this monthly series, we look at some common sustainability ideas to see if they are myth or true. In today’s episode of Sustainability Mythbusters: Is 3D printing the efficiency miracle solution everyone says it is? The Importance Of LCA Data Standards And Alignment LCA has existed for several decades now. But still, there are no clear standards for technical issues, such as substance nomenclature and data quality in LCA, among other. Every now and then, initiatives arise with a new passion to tackle this problem. Right now, several powerful initiatives are doing just that. This article explores the status quo of LCA data standards at this moment, and shows you the latest developments in changing it. Electric Cars Guarantee Green Mobility: Myth Or Not? As a science-based method, LCA is an excellent tool to bust the myths that surround sustainability. In this monthly series, we look at some common sustainability ideas to see if they are myth or true. In today’s episode we discuss electric vehicles. Are they really the best option? Growing Biofuels Causes Food Shortages: Myth Or Not? As a science-based method, LCA is an excellent tool to bust the myths that surround sustainability. In this monthly series, we look at some common sustainability ideas to see if they are myth or true. In today’s episode we discuss the concerns about the recent rapid increase in global biomass production. 5 Roads To A Circular Economy - Part IV: Sharing In a circular economy, the intention is to produce no waste or pollution. Instead, products, parts and materials are used, cared for, repaired, reused and recycled as much as possible. This requires new and innovative approaches to business, and assessment methods such as LCA to measure the effect. In our circular economy miniseries, we’ll address five ways to apply the circular economy in your business. Today: sharing in the circular economy. 5 Roads To A Circular Economy - Part III: Reusing Waste In a circular economy, the intention is to produce no waste or pollution. Instead, products, parts and materials are used, cared for, repaired, reused and recycled as much as possible. This requires new and innovative approaches to business, and assessment methods such as LCA to measure the effect. In our circular economy miniseries, we’ll address five ways to apply the circular economy in your business. Today: reusing waste. A Plant-based Diet Has A Lower Impact: Myth Or Not? As a science-based method, LCA is an excellent tool to bust the myths that surround sustainability. In this monthly series, we look at some common sustainability ideas to see if they are myth or true. In today’s episode: reducing impact by going without meat. Data Requirements In The PEF Approach For an LCA study to be compliant with the ISO 14040 and 14044 standards, it needs to include the data quality requirements and a data quality analysis. A lot of LCA practitioners who provide these required elements don’t derive actual value from them, though. They often do it to tick all the boxes. But why is this? And how is the PEF initiative changing this? The State Of LCA In Business To accelerate the adoption rate of fact-based LCA, we conducted a study to find out which are the struggles and drivers that are moving LCA practitioners in the business arena. This infographic is based on the most relevant outcomes from our study 'The State of LCA in Business in 2014'. Life Cycle Assessment And Cradle To Cradle: Friends Or Foes? There are many different sustainability tools, ranging from simple to complex and covering the various aspects of sustainability: environmental, social and economic sustainability. The popularity of these tools waxes and wanes. What’s more important than Life Cycle Innovation? Recently we saw the announcement of a new membership organisation which promises us the be “the voice of the LCA community”. It will be focusing on growing the market for LC based approaches, through advocacy, market expansion and what is called “advancing application”. LCA definitely needs to keep innovating and rethinking, so we agree on that. But, are the priorities set by this initiative right? Why “It Depends…” Is Often The Right Answer Environmental footprint assessment is a highly detailed technical tool for evaluating the environmental performance of products or organisations. This level of technical detail, however, often makes it difficult for sustainability professionals to give decisive answers to decision makers. Why Food And Beverage LCAs Are Difficult To Do Compared to several other sectors, such as the packaging, household and personal care, transport and building sectors, food and beverage LCA are only just catching up. What is it about the food and beverage sector that makes it so difficult to do good LCAs? How to Use USEtox® Characterisation Factors in SimaPro USEtox®, available in SimaPro, is a well-known model for characterising the toxic impacts of chemical emissions in a life cycle assessment (LCA). But what is it exactly and how do you use it? This article gives a short overview. Business Decision Making | Materiality Assessment vs. Hotspot Analysis Implementing a sustainability programme or choosing a new, sustainable business model can be somewhat of a conundrum. Without data, it’s impossible to choose. But if you do a sustainability assessment, you get so much data that you still can’t choose. Materiality assessments and hotspot analyses can help you move forward. Normalisation: New Developments in Normalisation Sets This is the second in a series of articles where PRé's own consultants explain a step in the LCIA process and the way their own expertise fits into that step. Tommie Ponsioen is a technical consultant at PRé, with expertise in LCA methodology and database development. This article explains normalisation, the third step in LCIA, and describes new developments in the field. Combination of LCA databases solves challenges for measuring environmental impacts satellite mission The European Space Agency (ESA) is an organisation gathering knowledge about the earth, its immediate space environment, our solar system, and the universe. It also develops satellite-based technologies and services and promotes European industries. Emerging International Consensus On A Truly Global Network of LCA Databases An intergovernmental process has been initiated to solve the problems around the lack of availability of life cycle data once and for all. The New Calculation Engine In SimaPro 8 SimaPro 8 has been equipped with a completely new calculation engine. The reason for this is simple. The old calculation engine worked well with life cycle assessment (LCA) models of a few thousand processes. But with the introduction of ecoinvent 3 - resulting in much larger models - SimaPro needed a software update to continue supporting the available data sources. The Footprint of Food: Consolidating Data The first LCAs were done on rather irrelevant subjects like baby nappies, milk packaging, and looking at whether you should use paper or washable cups for your coffee. Over the years, we came to realize that there are much more relevant areas. On Developing Globally Relevant LCA Databases As LCA becomes a more globally important and accepted way of measuring our environmental impacts and quantify sustainability in business, we will have to face our many problems. Updated Carbon Footprint Calculation Factors Scientific insight is continuously improving, providing us with information that helps our impact assessment calculations be more accurate and better able to predict environmental impacts and how much our products contribute to climate change. Understanding the landscape for sustainability metrics A sustainable future for your organization starts by understanding your business’s sustainability landscape. In this article Simon Evitts explains how to start with an integration roadmap and a sustainability metrics SWOT analysis. What does an LCA do, anyway? A 20 Year perspective What do carbon footprints, water footprints, environmental product declarations, the GHG protocol, and PAS 2050 all have in common? These metrics, B2B communication platforms, and standards all adopt a life-cycle perspective.
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Home » Vox Heritage Collection AC30H2 Review more... Gear • Amps • Reviews • EL84 • Tube Combo • January 2009 • Sound Samples • Vox Vox Heritage Collection AC30H2 Review Chris Burgess Ch. 1 (EF86 pentode mode) Vol. 2 o'clock, Brill. off, Cut noon Ch. 2 "Top Boost," Vol. 10 o'clock, Treb. 1 o'clock, Bass 11 o'clock, Cut noon Ch. 2, Vol. 1 o'clock, Treb. 2 o'clock, Bass 11 o'clock, Top Cut 9 o'clock Nash S63 Lollar bridge pup; recorded in Sound Studio on a MacBook Pro using Digidesign Mbox (SM57). Everyone knows that VOX is a name to conjure by. The AC30 in particular has achieved its reputation among all types of rock ‘n’ rollers by earning it over the long haul. Tonehounds know it as a great all-around amp with a sound entirely its own—as sought after for its bell-like, pristine cleans as it is for its raw, saturated overdrive that gets rich and creamy with just the flick of a knob. Anyone who’s ever played a good one knows it’s a dynamic, sensitive and responsive tone machine, and almost as simple as they come. A good guitar and an AC30 can be the quickest trip to tone heaven you can take. So, plugging a guitar into the handwired AC30H2 Heritage combo, made to celebrate VOX’s fiftieth anniversary, expectations are going to be… well, high. In addition to a reputation that precedes it, this amp has a smart vintage styling, with cream vinyl covering, gold trim and logo, light brown leather handles and brown diamond grillcloth, complete with a VOX 50th anniversary badge. Under the hood it sports a handwired circuit (using TAG board) with the usual EL84 power section, GZ34 rectifier and a pair of VOX/Celestion Alnico Blue speakers, as well as combining, for the first time, the EF86-driven preamp channel from 1958 with the ECC83/12AX7-driven Top Boost channel of the early sixties. I also have to admit I had high expectations for the EF86 preamp channel, which VOX phased out during the transition to the renowned AC30/6 Twin model. This pentode tube has a higher gain, but a reputation for becoming severely microphonic; although debate flourishes about the exact nature of the problem, most agree it can be temperamental. It’s also become legendary for its tone and character, which is why the EF86 has been showing up for years in VOX-inspired (and other) boutique designs by Matchless, Valvetech, Dr. Z, 65 amps, Top Hat and Xits, just to name a few. Channel one of the AC30H2 features two inputs and only one knob for volume. The remaining controls are all switches: a three-way Brilliance switch that offers a flat response and two other voicings for tone shaping; a Bass Shift switch for a vintage-correct or a tightened bass response; and a switch that changes the operating mode of the EF86 from Pentode to Triode. True to form, this channel boasts a somewhat darker, more aggressive sound, without so much of the chime or compression. It does have fat, punchy mids and a meaty grind, and a very different breakup than the more common ECC83/12AX7 preamp. It’s a splendid complement to the brightness and clarity of channel two—think down and dirty rock. The pentode mode does indeed put out a sweet high gain tone, but the triode mode has a less vibrant response and sounds dull in comparison. Personally, this option doesn’t appeal to me because I don’t see why you’d want to run a Pentode circuit in triode mode. The sound of channel two is the inimitable sound of the Top Boost preamp circuit. Everyone has heard the description, so perhaps I’ll narrate instead. For a test, I took the VOX out to a recent gig. Setting up for the sound check, I decided to forego my usual desire for versatility and run my new Nash S63 Strat-style guitar with Lollar pickups into the AC30H2 on the backline with no mic and nothing in the signal chain but an EH Small Stone Nano phase shifter (gotta have some of that Outlaw sound), a Lizard Leg Flying Dragon boost, and a Boss tuner. I had my Duesenberg out on a stand, and another rig ready to go, but I shouldn’t have bothered—I didn’t touch either one all night. Although I hadn’t played the Nash and the VOX together yet, I’d played them both and had a good feeling about the combination. Damn if it wasn’t the best decision I’ve made in months. The dynamic sensitivity was just right, and the clarity was just ridiculous. That rig merged into a single instrument that unceremoniously knocked me and my band mates out, over and over again all night. The shimmering, sparkly highs, the focused mids and low end, the compression, the richness of the harmonics, the breakup—all of it was brilliant. The sweet, ringing cleans opened up a lot of the tunes on which I normally look for a darker sound, and the vintage character of the tone was so warm and woody. The flawless sixties sounds would have been enough for me, but I also got some fat, muscly blues tones, SRV and Rory Gallagher tones, a seriously spanking country tone, and some delicious in-betweens—all without touching the amp. I stayed on channel two with the same settings for four and half hours. That might sound more like a testament to the quality of guitar and the pickups than the amp, but that kind of control is exceptional. The “swish” of that phaser has never sounded clearer, and it took the boost like a champ. And, while I’m used to using a bit of reverb and a slap delay every once in a while, I didn’t miss either of them—the openness and depth of the amp made up for their absence. The amp also offers output Pentode/Triode switching, which changes the operating mode of the EL84s as a way of achieving a half-power mode in the amp—the idea is to get the same cranked tone at tamer volume levels, but it’s not correct to say the volume is cut in half, or even necessarily “tame.” More importantly, changing to Triode mode seems to take some of the swagger out of the amp when it’s cranked, and I’m not sure about what I’m getting in return for giving that up. A half-power mode can be a useful feature (and clearly popular), but in this amp it seems like a shortcut. There are other ways to offer that kind of control, like “shutting off” one pair of output tubes while allowing the other pair to work the way they were designed. It’s not that I have a problem with this feature, it’s just another option I wouldn’t use. To be sure, any reissue should have an old-school look that harkens back to the days when it all began, but it’s the tone that really makes it a celebration, and the tone of this one is above reproach—two channels of real VOX magic. Although it’s got a vintage look, up close it discloses the signs of modern mass production: plastic vent covers, small flaws in the cabinet fit and covering—nothing major, but it’s got me wondering. For me, the downside is that I’d feel like I was paying for features I wouldn’t use, and it has a look I’d have to get used to; the upside is that an amp this good doesn’t need a lot of features, and it does have a look of its own. It’s dead simple to use, and it gives up great tones. My expectations of the AC30H2 turned out just a bit higher than what it delivered, but it unquestionably lives up to its name and reputation sonically. I have concerns about its roadworthiness, but I would have no qualms whatsoever about using it in the studio or on an occasional gig. you’re looking to add an AC30 (or another AC30) to your lineup, and you want it a bit different. you’re looking for more of a straight-up reissue or something better suited for road abuse. Street: $2000 - Vox Amplification - voxamps.com Recent Articles by Chris Burgess Nik Huber Krautster Electric Guitar Review Nik Huber Krauster Electric Guitar Review Fender American Special Stratocaster & Telecaster Reviews BilT Guitars Relevator Electric Guitar Review Potvin Guitars El Camino & Ranchero Electric Guitar Reviews Video Review: Vox Night Train NT15H Head Vox TB35C2 Bruno Amp Review Heritage H-137SC Review Vox AC10 Custom Review Vox Night Train G2 NT15C1 Review
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OpenLearn Live: 27th November 2015 Updated Friday 27th November 2015 The oldest parish in Ireland - then more free learning through the day. OpenLearn Live brings free learning into the heart of your world. This page will be updated during the day, or you can follow us on Twitter. Yesterday, it was turkeys or nothing See the complete collection of OpenLearn Live A week in County Waterford: Old Parish Times Higher Education Awards BBC One this Sunday: The Hunt Once again this Sunday we've got a double-hit of predatory action for you. First, at 4.50pm, you can catch up with Hunger At Sea; then, at 9pm the action switches back to dry land, as the struggle for survival on the plains is documented. For the prey, there's nowhere to hide: See more about The Hunt - and find out how to order your free poster Yesterday marked the 150th anniversary of the first publication of Alice In Wonderland. We're collected some Alice-related materials to celebrate. Anyone know how to get dormouse stains out a tablecloth? So, not a prize-winning night for our courses team at last night's Times Higher Education awards - but a brilliant night, nevertheless, recognising some of the great things being done in the UK's Higher Education sector. We're happy to applaud all last night's winners: University of the Year Most Innovative Teacher of the Year Momodou Sallah, De Montfort University Entrepreneurial University of the Year International Collaboration of the Year Southampton Solent University Outstanding Employer Engagement Initiative Outstanding Contribution to Leadership Development University of Huddersfield Widening Participation or Outreach Initiative of the Year Business School of the Year Newcastle Business School, Northumbria University Outstanding Digital Innovation in Teaching or Research Outstanding International Student Strategy University of the West of England Outstanding Support for Students Outstanding Contribution to Innovation and Technology Research Project of the Year Outstanding Support for Early Career Researchers Outstanding Contribution to the Local Community Excellence and Innovation in the Arts The Lord Dearing Lifetime Achievement Award In particular, warm congratulations to our nemesis in the Widening Participation category, Keele University - they won for a genuinely inspired project which takes a stardome out to schools to inspire pupils with the night sky. Also, delighted to see Laurie Taylor's lifetime achievement award - as you may know, we work with Laurie on Thinking Allowed and earlier this year he spoke with us at length about his interests. This week - coming between the two episodes of Ireland With Simon Reeve - we've been exploring some of the places in County Waterford. If you've missed any, here's where we've been: Kilmacthomas, where Cromwell was nearly sunk Cheekpoint, where perhaps Noah's granddaughter came to Ireland The Copper Coast, a buffet of rock types Dungarvan, birthplace of a Nobel laureate We're finishing up our week in Old Parish. Antairmdearg under CC-BY-SA licence under Creative-Commons license The Mine Head Lighthouse After mysteries of names earlier in the week, there's no dispute about Old Parish, or An tSean Phobail in Gaelic. It's the oldest parish in Ireland, although obviously it wouldn't have started out being called the Old Parish. Nobody is entirely certain - might have lied a bit about there being no dispute - what the "old" refers to; some think it might refer to a rejigging of parishes in the early 1900s; others that it could be an acknowledgement that the area had been turned onto Christianity by Saint Colman long before Saint Patrick turned up with his snake-scaring ways to grab all the spotlight. A third, more plausible explanation relates to how hard the area was hit during the famine. The parish saw so many starve to death so quickly that a new burial ground had to be opened. The population never fully recovered from the impact of the terrible deprivations, and long-abandoned cottages still pepper the area. The 'old', in this theory, is a sad acknowledgment of a vibrant community that had vanished, rather than a proud testament of longevity. There were some glimmers of humanity and hope during the famine years - the Quakers came to the aid of nearby fishermen based in Ring: Through [Reverend James] Alcock, aid was given by Waterford Quakers in a well-monitored scheme. Small loans were arranged and food for the boat crews given. By the summer of 1847 Alcock reported that 49 boats were helped, totalling 150 crew. Through these ongoing small grants and loans to individuals, the fishermen’s activities increased. Loans for new and better boats and nets enabled more fish to be caught. A further 6 months on, Alcock wrote in his report to Strangman ‘We have had, thank God, no destitution up to the present time, all are beginning once more to look cheerfully robust and comfortable. They are provided with sufficient supply of fishing gear for their immediate wants, and therefore constantly employed whenever weather permits’. Settlement at Old Parish reaches even further back than Saint Colman's times, though - there is a megalithic Crown Cairn in the area - unique, in that it is the only one in the South of the island and tells an important story: Although the Ballynamona Court Cairn is neither spectacular nor large its importance cannot be overlooked. It is known to date from 2000B.C. during the late Neolithic or early Bronze Age. It is clear evidence of the early settlement of Old Parish by a developed, agricultural society. A more recent building is the Mine Head lighthouse, built in the mid 1850s and still in use today (although it went electic in 1964). There had been rival plans to build a light on the cliffs on Capel Island, and work had even begun on construction there before the decision was made to switch to the Old Parish site. Today, the building is protected, and comes off well in the register of buildings of Ireland: An elegantly-composed lighthouse, built by the Commissioners of Irish lights to designs prepared by George Halpin (c.1775 - 1854), which forms a dramatic landmark on Mine Head. The lighthouse is of particular importance for its associations with the maritime industry that has traditionally supported much of the economy of County Waterford. The construction of the shaft attests to high quality stone masonry, which is particularly evident in the fine tooled detailing, while the lantern is of technical interest. Very well maintained, the lighthouse retains its original form and fabric. A collection of related outbuildings each of which retains most of its original character, enhances the group value of the site. And as we're at the coast again, this is probably a good place to leave County Waterford for now - there are, of course, stories untold - not least that of the town that gives the county its name, and the crystal that shares that name. Perhaps we shall visit again... See more about Ireland with Simon Reeve Explore OpenLearn Ireland Originally published: Friday, 27th November 2015 Image 'Mine Head Lighthouse, Old Parish' - Antairmdearg under CC-BY-SA licence under Creative-Commons license Image 'Plugs linked together' - pulpolux !!! under CC-BY-NC licence under Creative-Commons license Image 'Barack Obama on ABC News big screen ' - Copyright: By Herve Boinay via Flickr under Creative Commons licence Image 'Crimean war veterans, 1858' - Copyright free: Public domain Image 'Harriers Lined Up at RAF Cottesmore Following Retirement from Service' - Copyright: defenceimagery.mod.uk under open government licence Subscribe to our 'OpenLearn Live: 27th November 2015' When and Where feed Latest pages from OpenLearn - Events Latest pages from OpenLearn - History Latest pages tagged - OpenLearnLive Latest pages tagged - lighthouses Latest pages tagged - County Waterford Latest pages tagged - Ireland en-GB The Open University text/html Creative Commons BY-NC-SA 4.0 OpenLearnLive lighthouses County Waterford Ireland pulpolux !!! under CC-BY-NC licence under Creative-Commons license TEDxMiltonKeynes: Connections Copyright: By Herve Boinay via Flickr under Creative Commons licence US Presidential Elections 2012 Copyright free: Public domain OpenLearn Live: 14th March 2016 Copyright: defenceimagery.mod.uk under open government licence OpenLearn Live: 7th October 2015
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Join OpenChannels Join the OpenChannels Community The Skimmer & MPA News OC Overviews Login to Share News Login to Post a Blog Listservs & Updates Subscribe to OpenChannels Listservs & Newsletters Weekly Update Archives Literature Update Archives Freely-available Items Approximate Literature Costs SeaPlan Archives Submit to the Literature Library Office Hour Archives Submit a Conference Field-tested Tools Apps for Ocean Management and Conservation Apps for Ocean Conservation and Management, on Video Tools & Resources for Addressing Climate Change Impacts Tool Resources Voices in Ocean Planning: Lessons from Leaders Insights from Leaders: Practical Solutions on Ocean Planning A Guide to Evaluating Marine Spatial Plans Grants & RFPs All Grants & RFPs Submit a Grant/RFP Login to Post a Job Resources for Job Hunters OCTOPOD Salish Shes Dr. John A. Knauss, instrumental in founding NOAA's Sea Grant program, has passed away Posted on November 23, 2015 - 2:00pm, by nwehner Via URI "It is with great sadness that I write that Dr. John A. Knauss, founding Dean of the Graduate School of Oceanography (GSO), Under Secretary for Oceans and Atmosphere in the Department of Commerce, and Administrator of the National Oceanic and Atmospheric Administration (NOAA) from 1989 to 1993 died peacefully on November 19th following a period of declining health in Saunderstown, RI, where he had lived for the last 53 years. He was 90 years old at the time of his death. As founding Dean of the Graduate School of Oceanography, he created an oceanographic institution in 1962 at the University of Rhode Island that became nationally and internationally recognized for its breadth of oceanographic and marine programs. In partnership with Senator Claiborne Pell and Dr. Athelstan Spilhaus, he was instrumental in the formulation and development of the National Sea Grant Program in 1966 that has had a major impact on marine science, policy and management in the United States. He was widely viewed as an international leader in oceanography and marine policy over a long and productive career." Click here to read the full article from its source (note: external link) Each email address will be obfuscated in a human readable fashion or, if JavaScript is enabled, replaced with a spam resistent clickable link. Email addresses will get the default web form unless specified. If replacement text (a persons name) is required a webform is also required. Separate each part with the "|" pipe symbol. Replace spaces in names with "_". Allowed HTML tags: <a> <em> <strong> <cite> <blockquote> <code> <ul> <ol> <li> <dl> <dt> <dd> <p> <span> <h1> <h2> <h3> <h4> <h5> <h6> <sup> <sub> Sign-in with your OpenChannels Member Account and sign-up for email notifications of news. Simply visit any news post and click the "Subscribe to updates of new content of this type" link just above the comments section. PRIVACY POLICY | COOKIES | TERMS OF USE Questions? Praise? Technical problems? Send your comments, questions, or concerns to the OpenChannels Team at info [at] openchannels.org. We love to hear from our users!
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Call Him Mine by Tim MacGabhann Jaded reporter Andrew and his photographer boyfriend, Carlos, are sick of telling just another story. From cartel massacres to corrupt politicians, sifting the dregs of Mexico’s drug war, they think they’ve seen it all. But when they find a body even the police are too scared to look at, what started out as just another reportage becomes the sort of story all reporters dream of. Until Carlos pushes for answers too fast, and winds up murdered, leaving Andrew grief-stricken and flailing for answers, justice, and revenge. Caught in a web of dirty money that stretches from the boardrooms of the United States to the death squads of El Salvador, Andrew must decide whether to save himself – or find out who killed the man he loves, and destroyed the only home he’s ever known. (p) Orion Publishing Group Ltd 2019 Genre: Fiction & Related Items / Modern & Contemporary Fiction (post C 1945) On Sale: 11th July 2019 Audiobook Downloadable Arrow Icon A hilarious, gripping, poetic off-the-wall crime story set in a delirious Mexican underworld that William Burroughs, Sam Peckinpah & Hunter Thompson would have recognised. I loved it. Adrian McKinty, author of THE CHAIN A terrific, tightly-paced thriller that utterly transports its reader. With beautifully poetic visual description, the tale takes us from the saturated palettes and neon diffusions of Mexico City to the filthily polluted, crime-ravaged regions in the eastern part of the country - land rich with oil and horror... The sense of place, too, is utterly electric: with considered, efficient strikes, the story's sounds, smells, weather and colour diffuse across the narrative... Call Him Mine has been likened to 'Breaking Bad' and 'Narcos', and the narrative, with its fast-moving combinations of crucial quests, visceral violence and dark humour, is certainly gripping. But central to the trajectory of the plot is Andrew's uncovering of a scoop; though the subject may differ, the text's progress, in this respect, bears some similarity to the 2015 film Spotlight. Like Spotlight, it is cleverly composed of truths to be uncovered by the protagonist, and truths withheld by him - alluded to, and then gradually revealed in later stages. And like that film, MacGabhann's novel simultaneously informs and celebrates the diligence involved in gathering and disseminating that information: facts those in the highest echelons of power would rather stay deeply buried. Totally Dublin This impressive read from the Irish writer is a gay love story set against the backdrop of gangland Mexico. Indeed, it does have everything, including murder, mayhem, and espionage as journalist Andrew tries to find out how his boyfriend Carlos met his demise. A tough and uncompromising debut - you'll be glad you read it. Compelling and bold. Imagine Narcos crossed with Hunter S. Thompson's Fear and Loathing in Las Vegas crossed with Raymond Chandler's The Long Goodbye and you'll begin to have an idea of Tim MacGabhann's brilliant debut. A visceral, acid-soaked trip through Mexico's many underworlds, and a heartfelt testament to lost friendship, Call Him Mine pulls you in by the eyeballs, steals your wallet, tramples on your heartstrings, and somehow leaves you feeling uplifted and alive. Paul Murray, author of SKIPPY DIES and THE MARK AND THE VOID This gritty crime novel set in Mexico follows reporter Andrew as he investigates the murder of his own boyfriend. Brilliantly plotted, with a strong sense of the vibrant and violent setting, Call Him Mine is a must-read for those who were glued to Narcos and Sicario. Dead Good (Debut crime novels to watch out for in 2019) This audacious and ingenious combination of hardcore reporting and genre fiction gives the clearest account and synthesis I've read anywhere of the staggering horror that has befallen contemporary Mexico. If a young journalist really were to investigate the murder in Mexico of another daring journo and justice warrior who was also his lover, this terrifying, riveting, emotionally wrenching narrative is a realistic account of how that might go. But Call Him Mine gives the reader more than that, because Macgabhann is a writer of gritty poetic genius. This is the wired fevered enthralling Mexico City I live in. This is the most beautiful writing about Mexico in an English-language novel since Malcolm Lowry's Under the Volcano. Francisco Goldman, author of Say Her Name and The Interior Circuit: A Mexico City Chronicle Feverish, lyrical and gripping from beginning to end the Irish writer's crime novel is both a searing indictment of corruption and murder in Mexico and a darkly moving gay love story as reporter Andrew finds himself out of his depth and out of control as he investigates his lover Carlos's death. Independent (30 best books for summer 2019)
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It’s meal time, let’s eat! Do you remember being reminded by your parents, “don’t you have something to say?”, and then saying, “Itadakimasu!”? The phrase, “Itadakimasu,” that you are saying without much thought, is actually a phrase unique to Japanese. Why do we say “Itadakimasu” anyway? 1 The meaning of “Itadakimasu.” 1.1 To thank the person, who prepared the meal. 1.2 To thank the vegetables and animals that became the food. 2 The origin of the word, “Itadaku.” 3 The origin of the word, “Gochisousama.” 4 The use of “Osomatsusamadeshita,” the response to “Gochisousama.” The meaning of “Itadakimasu.” To thank the person, who prepared the meal. Those who cooked the meal, and those who provided the ingredients. Express gratitude toward many people including the fishermen, who caught the fish and the farmers, who grew the vegetables. To thank the vegetables and animals that became the food. The real purpose is through saying “I am eating life,” you are expressing gratitude toward the life you are about to consume, which was obtained by sacrificing a living thing and taking its “life.” Additionally, “Itadakimasu” includes the sentiment of repentance for the life you are about to eat. The origin of the word, “Itadaku.” Generally, “Itadaku” is said to be a humble expression (Kenjo-go) of “eat” and “receive,” derived from the act of holding up the food, once offered to god, before eating it or the gift from someone, who is at higher rank than yourself, on top of your head. In recent years, there are people who feel that it’s unnecessary to say “Itadakimasu,” at school or restaurants, because they are paying for the food. They should learn the meaning of the phrase, rethink their actions, and then eat their meals. The origin of the word, “Gochisousama.” “Gochisousama” is written “御馳走様” in Kanji. “Gochisousama” refers to “I have been treated.” Both “馳” and “走” mean “to run.” Therefore, the phrase is said to have originated as an expression of gratitude toward the people, who procured ingredients by traveling far away on horses, in order to treat important guests. “Gochisousama” is not only an expression of gratitude toward the food itself, but also toward the people, who went through a great distance to prepare the meal. The use of “Osomatsusamadeshita,” the response to “Gochisousama.” The origin of the word, “Osomatsusama.” This word is used to express humbleness, when someone thanks you for what you have provided. It is said with a sense that, “I’m sorry for not offering an amazing meal.” You can incorporate variations of this phrase by the company you are serving. You may want to say “Osomatsusamadeshita” to your friends, and at a more formal situation, you could ask, “was it to your liking?”. “Itadakimasu” abroad. In the United States, people say .“Amen”. to express gratitude toward god. It’s like saying, .“I thank god’.s blessings.” In Germany and Spain: .“Guten Appetit (have a good meal)”. in German. .“Buen Provecho! (please, eat!)”. in Spanish. Supposedly, both phrases contain .“gratitude toward all living things.”. In Islam, people say, .“we begin (the meal) in the name of Allah and his blessings.”. There is a theory that “Itadakimasu” and “Gochisousama” in Japanese came from Jodoshinshu. In Jodoshinshu, people put their hands together before starting a meal and say, “thanks for many lives and people’s efforts, we are blessed with this meal. We will deeply rejoice in the favor, and eat this meal with a sense of gratitude.” A meal is concluded with an expression of gratitude, “I will try harder to repay your favor for providing me with this previous blessing. Gochisousamadeshita.” What do you think? The words and phrases we utter regularly, without knowing their true meanings. “Itadakimasu” and “Gochisousama” are a unique part of Japanese culture. Take this opportunity to reconfirm their meaning, and pass them on to your children. Otsukaresama deshita 子供に説明できますか?「いただきます」と「ごちそうさま」の意味。 Foreigners ask, What’s ”otsukaresama”? Someone told me that Japanese people have ”Honne and tatemae” “Wabi” and “Sabi” have distinct meanings. タグ:“I will try harder to repay your favor for providing me with this previous blessing. Gochisousamadeshita.”, “thanks for many lives and people’s efforts, ” at school or restaurants, and eat this meal with a sense of gratitude.”, because they are paying for the food., before eating it or the gift from someone, Express gratitude toward many people including the fishermen, Gochisousama, In recent years, Itadakimasu, on top of your head., once offered to god, there are people who feel that it’s unnecessary to say “Itadakimasu, we are blessed with this meal. We will deeply rejoice in the favor, who caught the fish and the farmers, who grew the vegetables., who is at higher rank than yourself, いただきます Because it’s difficult, “Arigato”
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Five Questions with Garrett Hinson June 3, 2015 Bo Kitzman Since this article was written, Garrett has funded and produced his album "Nothing Is Destroyed." Garrett Hinson of Trenton, Tennessee, is no stranger to the artistic struggle, but what makes his struggle so interesting is how he has grown into his own brand of aural singularity. Folk and rock music are incredibly different than their traditional interpretations, and that’s part of what makes Garrett’s sound so enjoyable. Garrett applies the traditional and contemporary styles of folk and rock for a sound that doesn’t cross barriers but fuses them instead. Like many songwriters Garrett made his way to Nashville, Tennessee, to develop his sound and continue his education after high school. Garrett developed his writing chops along with a justifiable sense of disdain for the city in which he was residing. Hinson said, “I don’t like that songs are commoditized here. I also think that it’s counterproductive to force songwriters to compete. Instead of creating a community, the present music industry in Nashville is actually alienating us. That sucks.” Garrett’s new album, “Nothing Is Destroyed,” will certainly trump any doubt you have about the future of folk-rock. The record is genuine, is heartfelt, and conveys the message that the reality of what you want to create matters, no matter what. What does “Nothing Is Destroyed” mean to you? The phrase itself came to me when I was having these thoughts about reincarnation and the laws of conservation of mass and energy. It's just this idea that nothing is ever really created or destroyed; things are just transformed. As it pertains to the album, I think it's just a phrase of guarded optimism—evidence of some existential hope that crops up throughout the record. What was the most difficult part about creating the album? It's tempting to say the funding! But I don't think that's really true. Money isn't nearly as daunting as a songwriting drought. In the middle of writing this record, I experienced almost an entire year of writer's block where I didn't write anything. And that was miserable. But luckily I broke that streak by writing "What Do You Make of This World?", which I'm so proud of now. What do you want the listeners of “Nothing Is Destroyed” to walk away with? Well, first and foremost, I would want them to enjoy the stories. I've never been much of storyteller in my songs until this record, and I'm just really proud of how that experiment has turned out. But maybe more than that, I would want them to walk away with the same ambiguous, precarious sense of hope that I've found in writing it. What songwriters influenced this record the most? Josh Ritter, as a storyteller; Conor Oberst, aesthetically; and Joe Pug is definitely in there somewhere. Why do all Belmont kids look the same? White privilege? The futile quest for originality? I know for a fact that it's not because they just love to shop at Goodwill. To learn more about Garrett and to listen to his music, visit his Bandcamp site. Bo Kitzman is a senior at the University of Memphis' Lambuth Campus. Bo likes music and sports, but playing music is his favorite. You should buy Bo burritos. Bo loves burritos. Gather: July 2019 Courtney Searcy A Landscape in Lyrics Gabe Hart Hub City Brewing: Jackson's "Skyline" Moment Gather: February 2019 Stay 731: A Community of Investors Olivia Chin Quality First: How UrbanHouse - The Venue Introduced Third Wave Coffee to Henderson A Conversation with: Forked Deer Homeschool Parade What Will Bring You to The Dixie? A Curious Sight Gather: October 2018 Kevin Vailes Gather: September 2018 Megan Shulman Some Good Dinner Music Gather: August 2018 Gather: June 2018 Gather: May 2018 Jon Mark Walls Jackson Grown: Josh Miller Gather: April 2018 Gather: March 2018 A Tennessee Valentine's Go Cat Go!: The Life and Legacy of a Jackson Legend Austin Thompson There's Just Something About Moonshine Bo Kitzman A Conversation With: Colton Parker Celebrating Community: An Introduction to the TN Music Awards Theatre Review: Hello, Dolly! EP Review: Terry Prince & The Principles' "You Are Here" A Conversation With: Keegan Paluso categories Interviews tags Jackson TN, Tennessee, Bo Kitzman, Garrett Hinson, Trenton TN, music, musician, local music, folk, rock, Nashville TN, songwriting, Nothing Is Destroyed, Josh Ritter, Conor Oberst, Joe Pug, Belmont University Hello Jackson: Bubba Gandy Seafood A Bittersweet Holiday
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Out of the Rat Race Into the Fire by Paul Delahunt-Rimmer Home Testimonials Previews Biography A Visitor's and Walker's Guide to Amorgos Press Releases Contact Buy The Book A former pilot to the Royal Family and Henrietta his wife, an Air Traffic Control Officer, get 'Out of the Rat Race'. From the Cotswolds, Oxforshire to a remote Greek Island. Containing many anecdotes of island life this book permeates the traditional culture of Amorgos. It describes the trials and tribulations of living with no modern amenities and some of the resultant hilarious situations. This beautiful island with its craggy mountain ranges, clear blue sea and sky is an escape from the modern world. Some of the local characters and their little foibles bring to life an existence that has survived untouched for centuries. Substituting the fight deck of an aircraft for the rolling deck of a ship and the leather seats of a Jaguar XJS to the hard saddle of a donkey. Changing from switching on an electric light to lighting oil lamps or candles and turning on a tap to lifting water out of a well. These are some of the smaller changes that were managed with apparent ease. Over a decade later the author and his wife, Henrietta, are still there and very happy with their very basic existence. This book will make you think about your own way of life and the true values of modern needs. ISBN Number: 9780955628863 Our Other Websites » © 2019 Out of the Rat Race Into the Fire - Paul Delahunt-Rimmer | Sitemap | Policies & Cookies | Accessibility | LinkedIn | Marketing Analysis
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Kirkpatrick Law PC is Committed to Cybersecurity in SaaS Brian Kirkpatrick, Esq. attains the Certified Chief Information Security Officer and Certified Ethical Hacker certifications from the EC-Council in September and hires Heliane Fabian as the firm's Law Clerk for its growing cybersecurity and SaaS practice areas. Brian Kirkpatrick, Esq., C|CISO, C|EH A solid foundation in the legal and technology domains is imperative for strengthening the partnership between the GC and Cybersecurity organizations. Dallas, Texas Area (PRWEB) September 25, 2016 We are proud to announce that Brian Kirkpatrick has attained the C|CISO and C|EH certifications from EC-Council in an effort to better understand and mitigate the growing complexity of cybersecurity issues inherent in SaaS and cloud environments. This demonstrates the firm’s commitment to immersing itself into the information security community to better advise and partner with technical and executive digital information security professionals. Additionally, the firm is proud to welcome Heliane Fabian as Law Clerk to assist in the growing demands of the cybersecurity and SaaS practice areas. She assists Kirkpatrick Law with research, business transactions, and marketing activities as the firm grows. Brian Kirkpatrick, founding shareholder of Kirkpatrick Law PC, is a business and technology attorney who frequently reviews, drafts, revises, and negotiates technology agreements such as software licensing agreements and software as a service (SaaS) agreements. He is dedicated to improving cybersecurity controls in SaaS and other cloud based transactions to protect the intellectual property, Sensitive Personal Information, Personally Identifiable Information, and other confidential information of his clients. About Kirkpatrick Law PC Kirkpatrick Law provides legal assistance to entrepreneurs and companies in the areas of business organization, technology transactions, intellectual property, privacy, and cybersecurity. Brian Kirkpatrick Kirkpatrick Law PC @Software_Lawyer
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Former staffer to run BNC's corp entertainment business May 09, 2005 by Anita Chabria LOS ANGELES: Bragman Nyman Cafarelli has rehired a former staffer to head its TV, home entertainment, and corporate entertainment divisions. Tammy Golihew, most recently director of media relations at Sony Pictures Television, will return to the entertainment boutique, after departing the agency more than two years ago. While at Sony, Golihew oversaw publicity campaigns for shows including the 2003 miniseries Stephen King's Kingdom Hospital, and the VH1 special In Search of the Partridge Family. Bragman Nyman Cafarelli has entertainment and corporate clients including Jessica Simpson, Cameron Diaz, General Motors, and Sony Computer Entertainment. During her last tenure with the agency, Golihew worked on projects including the TV series American Dreams.
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Pro Sound News Moves To New Offices New York (July 6, 2010)--The editorial, art and production departments of Pro Sound News have moved to new offices in New York City as of July 6, 2010. The magazine’s parent company, NewBay Media, LLC., began moving into its new home at the Ziff-Davis Building (28 East 28th Street) earlier this year, first moving the magazines TWICE, Broadcasting & Cable and Multichannel News into the space a few months ago. All of NewBay’s New York City-based magazines, websites and services will be located at the East 28th Street offices by year’s end. The new address is: Pro Sound News NewBay Media, LLC. 28 E. 28th Street, 12th Floor www.prosoundnews.com Jay-Z and Eminem Rock Pro Sound News SSL Moves LA Office DiGiCo Group One Move LA Office To Vegas Happy Holidays From Pro Sound News Tweetastic Pro Sound News July 2010 Twitter Feed AES Recap: Pro Sound News&#39; Convention Twitter Feed There's More - Pro Sound News, July, 2015 Powersoft Moves To New US Headquarters Summertime Tweet: Pro Sound News&#39; June Twitter Feed
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Glenn Ligon, American (1960 - ) Glenn Ligon is known for his resonant works in multiple media that explore issues surrounding race, sexuality, identity, representation and language. For his first web-based project, Annotations, Ligon revisits the family photo album, a format rich in its potential for investigating the diverse sources that shape individual identity, in the artist's words: "a site of invention, cheering fictions, hidden histories and unforeseen juxtapositions." In considering this medium for his project, Ligon was inspired by a notion of the web as a vast, anarchic library of material, where family histories are researched and documented in places as diverse as personal homepages and genealogical sites. He is interested in the web as a repository where public and private collide in myriad ways, where even intimate photographs may be posted for a few to visit, yet are ultimately accessible to millions, remaining in archives long after removal from their original location. Ligon's works frequently employ appropriation or quotation, notably his lush coal-dust paintings of excerpts from James Baldwin's Stranger in the Village, or his recent project at the Walker Art Center, where he gave school children vintage coloring books depicting icons of African-American history, then used their drawings as the basis for a series of paintings. Ligon deems discarded materials and forgotten histories fertile source material for critical artistic practice. Ligon previously worked with the convention of the photo album in Feast of Scraps, 1994-1998. This work juxtaposed family photographs with vintage gay porn, humorously underscoring how selective and limited are the images that constitute a family's official history while probing silences around issues of gay sexuality. He captioned the pornographic photos with text snippets ("Brother," "Mother Knew" or "It's a Process") which served simultaneously to illuminate and obfuscate the interpretation of the images. In Annotations each image in the twenty-page album leads to a second or third layer -- a simple caption, other photographs, images of book covers, lists, narratives, a hand-written letter, and in a few instances, multiple page spreads -- plus, (towards the end of the album), audio clips of music, including the artist singing a capella or with songs from the 70s and 80s. The potential for adding layers of materials behind a single image allowed Ligon to present his material in a manner parallel to the way memory works: when viewing a photo album that one knows, each photo invariably prods recollections or associations. In this instance, where the album is unfamiliar to the viewer, Ligon provides hints and suggestions to multiply the layers of possible interpretation. Beyond the singular feel of many of the images in Annotations, African-American history and race are ubiquitous subtexts that run throughout, from the interspersed photos of book covers such as "Harlem is Burning" or "Black Like Me" to the charged captions "Came North" for a family standing around a car or "Future President of the United States" in front of an African-American baby. Another caption which appears repeatedly throughout the project references the 1955 exhibition and publication The Family of Man, one of the most well-known and successful attempts to postulate a universality inherent in the human condition. "We two form a multitude," the well-known Ovidian quotation, appears beneath photographs of couples from many continents and races, all heterosexual. Ligon wryly acknowledges this gap in universality with his placement of this caption throughout the album. The fact that the majority of the people in Annotations are African-American makes race a palpable factor in the reading of each image. Yet there is a feeling of recognition, even if none of the faces is known to the viewer, a familiarity that arises from our intimacy with the conventions of a family album -- the proud portraits, new babies, special occasions, banal moments when a camera was in hand, the poorly centered or focused images that make their way past the editing process for whatever reasons. Sara Tucker In the foreground of a generation of artists of the end of the years 80 and beginning of the years 90, Glenn Ligon has his fame to paints and to conceptual phototextes that explore the problematic aesthetic one, social, linguistic and politics of the race, sex and sexuality. The practice of Ligon, that draws to sources as varied as of the literary texts of James Baldwin and sketches of the comical Richard Pryor, understands the paint, the engraving, the sculpture, the installation and the video. The traveling exposition Glenn Ligon: Some Change track the evolution of his artistic gait during the seventeen last years and explores the notion of "revision" that, with Ligon, translates itself by a modification and a layering of subjects and previous themes resulting in a corpus of unpublished works. The work of Ligon is a sustained meditation on the quotation, the ubiquitousness of the passed and the representation of oneself in comparison with the culture and to the history. The paint is for Ligon a privileged tool in the matter of the commerce of the ideas, notably the one influenced by the aesthetic modernist and by the inherent incoherences to the comprehension of the perception that have the corporation and the media of politics of the black body. The historic fragments that the artist appropriates are the object of itself repeated and poignant transfers enters different mediums, but meet again invariably restored and retransformés in his paint. There is no doubt that the elaboration of a reflection on the artistic creation is at the heart of the gait of Ligon, at once as sat conceptual of his art and as criticizes corporation in which let us live us. The paint is only the an of its "key rocks" proved. With Ligon, the choice of a medium rests completely on his capacity to extract the resonance of its subjects and of its materials. Glenn Ligon: Some Change offers a rare occasion to appreciate an important corpus of works dating back to 1988 to our days, including Untitled (I'S Am HAS Man), Runaways (Fugitives, 1993), the series of pictures of Richard Pryor (1993-2004), Annotations (2003), a project Internet first, and the installation The Orange and Blue Feelings (the orange and blue impressions, 2003). The exposition understands equally a new series of drawings coming from the playful appropriation of albums to color african-americans of the years 1960. If all the works play an important role in the work of Ligon, certain of its pictures the more known allow wondering on the importance of the paint in comparison with its realizations in of other mediums. Each of the pictures is extremely complex, by the form, the materials and the subject, and collectively, in so as composing from a work in course. The process "révisionnel" of Ligon enriches the work and favors a dynamic meditation. It is a matter of a creation process deliberately twisting of which form them and the subjects withdraw themselves on themselves, réactualisés and revitalized. This is equally a process autoréférentiel that puts to contribution all a range of forms – pictures in movement, installations, photos found, big photographic continuations formats and other mediums and technical. Every incursion in another medium releases a reaction in the paint of Ligon – reminder disrupting that the modernistic paint can remain opened and receptive to new information without renouncing his ideal double of universality and of intemporalité. Wayne Baerwaldt.
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AdmissionsTransport Rowan Brae and Rowan Hill are situated in residential areas away from busy main roads. Both sites are a short walking distance from each other (0.4 miles) and are close to the main shopping area and railway station. The K3 bus that runs between Kingston and Esher stops approximately a five minute walk from both sites. Rowan Preparatory School At Rowan Brae an informal one-way system operates down Gordon Road (school on left hand side) and parking is not allowed in front of the school building. Between 8:30am and 8:45am 'drop and go' operates for parents of girls in Reception to Year 2 to park at the front of the school where a member of staff will help each girl out of the car and to the playground. For all visitors to the school we suggest parking in Claremont Road. At Rowan Hill an informal one-way system operates along Fitzalan Road (from Foley Road to Beaconsfield Road) and we suggest parking on Foley Road or Beaconsfield Road. MINIBUS SERVICE - MORNINGS ONLY To reduce congestion on local roads and in particular around the school, Rowan operates minibus collection routes in the morning to take pupils to Rowan Hill. The service is available for girls at Rowan Hill, Years 2-6 only and uses the Rowan minibuses. The routes have been chosen to provide pick up locations where parents/carers can park to see their daughters safely onto the minibus and with reference to the most common areas on the pupil address list. Pick-up points currently include: Cobham, Walton, Esher, Weybridge, Thames Ditton, Kingston, Surbiton, Wimbledon, Putney, Hinchley Wood and Claygate. There are 14 places per minibus and only pupils with reservations will be transported. If you are interested in your daughter using the bus service and would like to discuss the routes available, please email transport@rowanprepschool.co.uk stating your child’s name, form and where you live. Bookings will be on a first come first serve basis and will be confirmed by email.
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Take Action Donate Episodes About About Us Contact Us Take ActionDonate A Podcast on All Things Repro. Bonus Pod: Crisis Pregnancy Centers, SCOTUS and Why We Need to #StopKavanaugh Crisis Pregnancy Centers are centers that exist to deter pregnant women from receiving abortions. They provide pregnancy tests, anti-abortion counseling and material resources for pregnant women. There are an estimated 2,750 Crisis Pregnancy Centers serving 2.3 million people in the United States today. This number might seem high, but it is actually a low and out of date estimate from 2010. In this episode, we talk to Amy Myrick with the Center for Reproductive Rights about Supreme Court case National Institute of Family and Life Advocates v. Becerra and what it would mean for Brett Kavanaugh to replace Justice Kennedy. Crisis Pregnancy Centers receive funding through private and government sources and have sophisticated marketing and outreach through the internet. It is vital to remember that the way CPCs represent themselves online does not accurately reflect the services that they provide. CPCs often physically position themselves near abortion providers and adopt similar names as to confuse those that are seeking abortions (like Center for Pregnancy Choices). CPCs don’t make it clear exactly what type of facility they are. They often fail to disclose on their website whether they provide abortion or contraception. These clinics are masked by fake names and misinformation, and those who find them online assume that they offer comprehensive reproductive health care. Women who look at these websites or arrive at the facilities may not be aware that CPCs only offer certain services, and those do not usually include abortion, abortion counseling, or contraception. What results is women being counselled against abortion due to Crisis Pregnancy Centers’ overwhelmingly religious and traditionally Christian agenda. CPCs in California recently challenged a state law called the FACT Act. The FACT Act affects both unlicensed and licensed CPCs, and seeks to ensure that patients have the general knowledge that there are programs that provide coverage for contraception and abortion care. For clarification’s sake, licensed Crisis Pregnancy Centers were instructed to put up an on-site sign that explained that California has clinics that provide comprehensive reproductive health services, including abortion. Unlicensed CPCs were instructed to display an on-site sign that said it was not a licensed clinic and does not have provision of services. Both licensed and unlicensed centers were required to clarify this in advertising, as well. California CPCs challenged this law under the claims that it violated free speech rights and religious freedom rights under the first amendment. The first stage of litigation in district court stated that neither their freedom of speech or religion rights were violated. California Crisis Pregnancy Centers appealed and the California 9th circuit affirmed that their rights weren’t violated either, so CPCs appealed to the Supreme Court. The Supreme Court voted in favor of California’s Crisis Pregnancy Centers under the guise that the required licensed-sign was unconstitutional because it mandated controversial speech about abortion. They further ruled that the unlicensed-sign was unconstitutional because it was unjustifiable. Justice Anthony Kennedy, while not a champion of reproductive rights or abortion, was often a deciding vote on abortion cases. Donald Trump has continuously promised a litmus test that any of his picks for SCOTUS must oppose Roe V. Wade. With Justice Kennedy’s retirement and the nomination of Brett Kavanaugh you are seeing a turning the balance of the court against women’s constitutional rights, including abortion and that is extremely dangerous. Brett Kavanaugh, the current nominee for Supreme Court Justice, has overt red flags regarding abortion on his record. He has praised Justin Rehnquist’s dissent of Roe and has previously ruled against a young migrant teenager, Jane Doe, when trying to terminate her pregnancy earlier this year. Photo by Claire Anderson on Unsplash Links from this episode Center for Reproductive Rights Center for Reproductive Rights Facebook Center for Reproductive Rights Twitter Information on the FACT Act Brett Kavanaugh's confirmation to the Supreme Court would be disastrous for reproductive rights around the country. Call your Senators and urge them to stand up and save Roe! You can write op-eds, blog posts, letters to the editor, and social media posts using the hashtags #SaveSCOTUS #ProtectRoe #WhatsAtStake and #StopKavanaugh. Contact the Capitol Switchboard at 202-224-3121. You can also write a letter to the Senate Judiciary Committee—all letters written to them become searchable public record. Go to your Senator’s town halls before the Brett Kavanaugh confirmation vote and urge them to vote no. Find mobilization efforts in your area that are put on by organizations like NWLC and Indivisible. These include protests, events, rallies, and demonstrations. Follow Center for Reproductive Rights on Twitter and Facebook. Season 1Firas Nasr September 4, 2018 Episode 22Comment Let's Talk About Sex...Ed Season 1Firas Nasr September 11, 2018 Episode 23 Title X is Under Attack Season 1Firas Nasr August 28, 2018 Episode 21 rePROs Fight Back is sponsored by the Population Institute. Sign up to receive updates from the frontlines. © RePROs Fight Back 2017. FN Creative Console.
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>> Local Bus fire in southeast Las Vegas leaves one person in custody Firefighters and Las Vegas police are investigating a possible arson after a bus caught fire in the southeast valley Sundaymorning, according to the Clark County fire department. By Kimber Laux Las Vegas Review-Journal April 7, 2019 - 1:29 pm Clark County Fire Department (Las Vegas Review-Journal) Firefighters and Las Vegas police are investigating a possible arson after a bus caught fire in the southeast valley Sunday morning, according to the Clark County fire department. Two people were living in the bus, which was parked in a parking lot in the 1700 block of East Tropicana Avenue, near Spencer Street, with permission from the business owner, according to Metropolitan Police Lt. Chris Holmes. Fire Chief Greg Cassell described the bus as a “tour van.” The pair were in an argument before the fire broke out at 10:54 a.m. Sunday, Metropolitan Police Lt. Chris Holmes said Sunday afternoon. They were the only people on the bus. “At one point one of the individuals intentionally set the bus on fire,” Holmes said. “One party is in custody.” The person who was not in custody suffered minor injuries, he said. Holmes did not know the age or gender of either person. Contact Kimber Laux at klaux@reviewjournal.com. Follow @lauxkimber on Twitter. Posted on: Local Las Vegas police coax man to toss knife, come off central valley roof By Mike Shoro / RJ July 15, 2019 - 11:38 pm July 16, 2019 - 1:36 am A man is cutting himself on top of a roof Monday night in the central Las Vegas Valley. Police are trying to coax him down and have evacuated parts of the area. Las Vegas homicide detectives investigating central valley death Homicide detectives are investigating the Monday night death of someone who was initially reported to have died by suicide, Las Vegas police said. 3 sought in robbery at northwest Las Vegas business Three people are wanted in a robbery from this weekend near West Lake Mead Boulevard and North Torrey Pines Drive, and Las Vegas police are asking for help identifying them. Las Vegas woman charged with murder in ailing mother’s death A 50-year-old woman stands accused of murder in her mother’s death. Her 73-year-old mother was unable to care for herself, and she refused to seek medical care, an arrest report alleges. ‘Storm Area 51’ prank on radar of Nevada businesses, military By Christopher Lawrence / RJ “Storm Area 51, They Can’t Stop All of Us,” the jokey Facebook event created by pranksters on June 27, achieved critical mass Monday with more than 1.2 million people pledging to “see them aliens.” Police seek man in east Las Vegas armed robbery By Tony Garcia / RJ Anyone with information is asked to call the Metropolitan Police Department’s commercial robbery division at 702-828-3591. Blue Angel memorialized in massive mural in downtown Las Vegas By Janna Karel / RJ July 15, 2019 - 7:15 pm July 15, 2019 - 11:51 pm The Blue Angel has since descended from her perch at the Blue Angel Motel. And Stanford is commemorating her in a new mural, “A Phalanx of Angels Ascending.” Winning Las Vegas City Council candidates spent more than $1M By Shea Johnson / RJ The period between April 1 and June 30 easily accounted for the majority of candidates’ total campaign contributions and spending, according to an analysis of financial disclosures due Monday. Las Vegas comedy great Pat Cooper notches No. 90 By John Katsilometes / RJ Pat Cooper was funny as ever and surrounded by family and friends, including his wife, Emily, at the Italian American Club’s decked-out showroom.
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THE NEW YORK TIMES! Completely over the moon/shocked/elated (all the good emotions) to have my name mentioned in the New York Times amongst some fabulous Irish ceramicists. Amazing to have Irish ceramics celebrated in this way and put firmly on the map for design led products inspired by our wonderful landscape, #proud. Follow the link and have a read https://www.nytimes.com/2018/10/25/style/irish-ceramics-made-for-collecting.html The Bay Collection is directly inspired by the ever changing splendour of Dundrum Bay where Rebecca's home is situated. 'Each morning I am greeted and blessed with the most wonderful views which spread across the bay, leading to the majestic Mountains of Mourne'. The winter morning skies streaked with pink and gold are a beautiful contrast to the stunning shades of summer blues that encompass the bay throughout the warmer months. Each piece in the Bay Collection is completely unique with marbled bone china, painterly brush strokes and hints of gold lustre. TagsIrish Ceramics, Irish Design, Contemporary Irish Ceramics, Made in Ireland, Handmade Ceramics, new york times irish ceramics, new york times, new york times ceramics IRISH DESIGN SHOP - STORIES The Irish Design Shop kindly invited me to be featured on their ‘Stories’ where I chat all about my new studio space and the processes involved in creating the Homegrown Collection. Rebecca Killen is an award-winning ceramicist based in picturesque Castlewellan, Co. Down. She specialises in slip casting to create both functional and decorative pieces which draw on a sense of nostalgia. Rebecca's work is available to purchase here. -Tell us a little bit about what you make: I aim to create ceramic products that can evoke memories, a sense of nostalgia or serve as decorative pieces in the home to be used and treasured for years to come. Our bottles, dishes and vessels are made in small batches using the slip casting technique. This involves pouring liquid bone china into plaster moulds which I have made from found objects and turned forms. -Could you describe your studio to us? What is your favourite thing about the space and how do you get into the mindset of making? I have had a busy and exciting Summer, moving into my very own ceramics studio. The space is located at a horse riding centre beside a forest in Castlewellan, Co. Down. It used to be a tack shop for the centre but when I arrived we had a blank canvas to play with, to make our own and create a multipurpose space where I can work from and display the products. I have tried to create an inviting studio where people can not only view and buy the work but also get an understanding of how the pieces are made. My favourite thing about the space is the tranquillity of the location, it is so peaceful with beautiful views across the County Down countryside yet there is a certain buzz about the place with people coming and going to the trekking centre. To get into the mindset of making I usually listen to podcasts or audiobooks, they really help me to focus on the day’s tasks and when doing some of the more repetitive parts of the making process. Some of the podcasts I listen to are orientated towards pottery and creative businesses where others are purely for escapism. What is your favourite tool and why? I don’t use anything overly complicated in the studio, but couldn’t create the work I do without a few simple tools; fine paintbrushes, sharp pottery knives and I seem to get quite attached to certain sponges that fit precisely in my hand to smooth along the rims of the bottles. -Can you describe the making process and inspiration behind your Homegrown collection? I love working through all the required processes to make a piece of work, it takes around 2 weeks from start to finish but there is something very relaxing about getting into a rhythm of working whether it be casting a batch of work, sponging away the little impurities in the clay, glazing the pieces or applying the hand painted decoration. The Homegrown collection celebrates places of historic industry throughout Ireland. I have been collecting beautiful antique bottles from old mineral water companies and pharmacies for a few years. The shapes and textural detail on the bottles are really intriguing and aim to connect the viewer to a particular place. All the pieces are created using bone china, in itself a material with traditional associations but I hope to bring a fresh approach to the medium with the Homegrown collection offering bottles in millennial pink, dusky blue and white each finished with stripes of gold along the rim. What led you to choose this craft as a profession? What do you love most about it? I have loved working with clay since studying art at school, my teacher was also a potter and his passion for clay was infectious so he has a lot to answer for. My journey into a career in ceramics has been quite methodical, I specialised in ceramics at the Belfast School of Art and took a year out to study business at a liberal arts college in the States. After graduating, setting up a business combining my passion for ceramics and my new found skills in business felt like a natural progression. In saying this it hasn’t been all plain sailing, I have had so much help over the past few years with business and creative mentors and have completed a business development scheme (Craft NI’s Making It programme) which was massively beneficial in the early growth of my business. I feel so blessed to be able to do what I love every day, it is such a privilege and something I try to not take for granted. I am loving being in my new studio, opening this space has really been a dream come true for me. Tagsirish design shop, irish design, Irish Ceramics, Rebecca Killen Ceramics THE HOMEGROWN COLLECTION The Homegrown Collection is growing...In April 2017 we launched the collection with new Belfast bottles and an older milk bottle shape in millennial pink and pure white. After the encouraging reception of the range I am delighted to share our brand new bottles, in a brand new shade. The Homegrown Collection, a family portrait. Introducing the Bangor Bottles, cast from a mould of a gorgeous rectangular pharmacist bottle, if only our medicine still came like this. Say hello to another from the mineral water family, this time in our new shade of dusky blue, all the way from Trim, County Meath. I know I shouldn't have favourites but...... Hello, I'm pink, I have a heart and I'm from Newry ;) Wondering how to style the Homegrown collection? Single stem minimalism, let the Newry bottle do the talking. Or a small posy of gorgeous blooms from the fabulous Foxtrail Flowers who ALWAYS deliver the goods. The Clonard bottle looking right at home. The classic Milk Bottle, an oldie but a goodie :) The Homegrown Collection celebrates local historic industries from across Ireland and I hope to continue growing the family as I come across beautifully textured bottles that give us a glimpse into the past. A massive thanks to the amazingly talented Esther Irvine Photography for bringing the Homegrown Collection to life. To shop the collection visit my Etsy store CategoriesHomegrown Collection TagsRebecca Killen Ceramics, Homegrown Collection, Esther Irvine Photography, Handmade Ceramics, Irish Ceramics, Made in Ireland, Contemporary Irish Ceramics, Irish Design, Contemporary Bone China, Home Decor, Interior Accessories COLLABORATION WITH ESTHER IRVINE PHOTOGRAPHY Earlier this year I did a very exciting product shoot with talented Northern Irish photographer, Esther Irvine and I couldn't be happier with the results. If you follow Rebecca Killen Ceramics on social media you may have noticed Esther's fabulous work. Esther also came to visit the studio to get a 'behind the scenes' insight into how our bone china products are made beautifully capturing each step of the creative process. Check out Esther's latest blog post, not only is she is a super talented photographer she also has a beautiful way with words. Thank you Esther x ETSY AWARDS AT LONDON DESIGN FAIR Wow what an incredible competition to be apart of! We are so honoured to have won the regional award for Northern Ireland in the Etsy UK and Ireland annual competition and part of our prize was to exhibit a selection of our work at the London Design Fair at this years' London Design Festival. Check out some pics of an inspiring weekend in London. Our Cobalt Bottles exhibited in the Etsy stand alongside fellow Northern Irish designer Katie Brown's silk scarves, Yvonne Ellen's upcycled plates and Ireland's Matt Jones turned bowls. CategoriesAwards TagsEtsy Awards, Regional Winner, Rebecca Killen Ceramics, Northern Ireland, Award, London Design Fair SLIP CASTING WORKSHOP AT TORY BUSH On the 3rd September we took our third slip casting workshop at Tory Bush Cottages situated at the foothills of the Mourne Mountains. We had a full group with one lovely lady coming all the way from Austria to join in on the Creative Weekend. We began the morning session with an introduction to slip casting, explaining and demonstrating the industrial yet creative process that I use to create my work. We then all got to work on our own bottle casting into pre prepared moulds using fine bone china. While the bottles remained in the moulds for a couple of hours we got started on another technique in which we used plaster and underglaze to create a unique bone china tile. After a beautifully prepared lunch by Claire we were then able to take our bottles out of the moulds, and after a little cleaning and sponging, apply our own hand painted surface pattern. Everyone did such an amazing job on their bottles and tiles, the results speak for themselves... The bottles and tiles have all been taken away to my studio where they will go through a bisc and glaze firing. The bottles can be used either as a functional flower vase, or milk jug or a lovely piece to remember your weekend at the Mournes! Our next Creative Weekend in The Mournes is on the 15th October and spaces are filling up fast. 1 nights accommodation at Tory Bush Cottages 2 workshops (ceramics and print) Home cooked meals for the duration of your stay Refreshments during workshop info@torybush.com Ph Claire 07866928846 or David 02843724348 or message us at the facebook page https://www.facebook.com/CreativeWeekendsMournes/ All of the above for just £185 CategoriesWorkshop TagsWorkshop, Slip Casting, Bone China, Northern Ireland, Ceramics, Rebecca Killen Ceramics, Tory Bush Cottages ETSY AWARD WINNER WOOOOHOOOOO we won the regional award in the 2016 Etsy UK and Ireland Awards and will be representing Northern Ireland in the winners showcase at the London Design Fair at Tent London, 22nd-25th September. Thank you so much to everyone who took the time to vote for the Cobalt Flower Bottles in the People's Choice Award and although it didn't win I am overwhelmed by all support throughout the campaign. MAKE YOUR OWN BONE CHINA BOTTLE WITH REBECCA The Craft Weekends at Tory Bush consist of two full day workshops, accommodation for two nights, home cooked meals and refreshments and cake during the workshops. £185/person 24th-26th June - Ceramics and Printmaking 2nd-4th September - Ceramics and Printmaking *DAY WORKSHOP PACKAGES ALSO AVAILABLE* £45/person To inquire about taking part in the Tory Bush Craft Weekends, please get in touch. Either contact Rebecca - Click here Or contact Claire 07866928846 or David 02843724348 from Tory Bush Cottages. Rebecca has teamed up with Tory Bush Cottages in County Down, to give you the unique opportunity to create your own bone china bottle in the most idyllic setting. Tory Bush Cottages is situated in the foothills of the Mourne Mountains and the views are truly breathtaking, the perfect setting for our slip casting workshops. The workshops run from 10am - 4pm with breaks for a tasty home cooked lunch and freshly baked scones, cake and tea throughout the day. Rebecca will guide you through the slip casting process, where you will each make your own functional bottle using fine bone china. The bottles remain in the moulds for a couple of hours, so while we are waiting you will have the opportunity to create a beautiful ceramic tile using a printing technique with under glazes and plaster. Why not use the stunning surroundings as a source of inspiration for your work. Or use your own art work as a source of inspiration. Once the bottles are removed from the moulds they are now ready to be decorated using under glazes, this is your chance to really make your bottle unique! Rebecca will then take your bottles and tiles off to the studio to be fired and glazed and fired again ready to be delivered in a couple of weeks. The bottles can be used either as a functional flower vase, or milk jug or a lovely piece to remember your weekend at the Mournes! VOTE FOR REBECCA KILLEN CERAMICS IN THE U.K & IRELAND ETSY AWARDS We are completely over the moon to be shortlisted for the UK and Ireland Etsy Awards. The Etsy Awards celebrate the best of creativity in the UK and Ireland. Entrants have the chance to win up to £10,000 cash prize, product showcase at Tent London during London Design Festival, business support from The Design Trust, retail opportunities with John Lewis and more. With over 3000 entries Rebecca Killen Ceramics has reached the last 60 with the popular Floral Cobalt Bottle but now we need your help.... To win the people's choice award of a £10000 bursary (that could transform our small ceramic business) you need to vote and validate if using your email address. Click on link to vote if you like our handmade bone china bottles. VOTE FOR REBECCA KILLEN CERAMICS You can now also buy our handmade bottles from the etsy shop, click to check it out and purchase a piece of handcrafted bone china. TagsEtsy Awards, Etsy New Talent, Rebecca Killen Ceramics, Bone China, Bottles, Vote INTERVIEW WITH CULTURE NORTHERN IRELAND The lovely Jane from Culture NI got in touch to chat about my involvement with Tory Bush Cottages craft weekends and what has lead me to a career in ceramic design (making milk bottles for a living). Making It in the Mournes Newcastle ceramicist Rebecca Killen on finding commercial success for her signature crafts and showing South Down sightseers how it's done Spring and summertime in the Mournes. It’s a tantalising prospect, awakening visions of green fields, lush blossom, glorious mountain scenery, all in an area where rural traditions remain an integral part of everyday life. Nestled into sloping meadowlands, with Slieve Donard and the dense woodlands of Tollymore Forest Park rearing up behind, Tory Bush Cottages are a popular haven with visitors seeking refuge from stress, routine, hustle and bustle. Over the next few months, proprietor David Maginn will be showcasing South Down's rich artisan history with three creative weekends, comprising accommodation, home cooked food, great views and expert tuition in ceramics, willow weaving and print making. In charge of the three ceramics courses is 29 year-old Newcastle born Rebecca Killen. Killen is one of a new generation of exciting young Northern Ireland craftworkers who are establishing themselves and their work in the UK and further afield. A graduate in fine and applied art from the University of Ulster, she is achieving international recognition for her attractive range of bone china milk bottles, dishes and vessels, all featuring her trademark white and cobalt blue colour palette. It is one thing for a young artist to aspire to setting up his or her own business and getting the work into commercial outlets, but it is quite another to do it. Killen has been exceptionally strategic and focused in pursuing her goal and achieving the skills necessary to compete in the global marketplace. She is the first to admit that having an artistic talent is just the start. 'During university, I took a year out and did a business-related course at Monmouth College in Illinois,' she says. 'I learned a lot of new skills, like advertising, marketing, international economics. I came back home to finish my degree and, after graduating in 2011, I did an additional course at the art college, developing my work with the support of a studio space. It was a bit like an artist-in-residence programme. 'I always knew that I wanted to continue the making process. I was determined to earn a living out of my ceramics and I was aware that I would have to invest a lot of time and energy to make that happen. When I finished my course, I worked as an art technician at Down High School in Downpatrick, which was my first experience of working with children and taking workshops. I enjoyed it very much and it led to my working with clay in different ways.' Killen was one of eight craftworkers, all female, who were accepted onto Craft NI’s Making It 2013/2015 programme. Her host organisation was the Southern Regional College in Newry, where she was given her own studio, together with professional mentoring in the practicalities of business start-up. 'It was great to get to know the others in the group,' she recalls. 'They were working in ceramics, jewellery design, screen printing, glass and textile design. We were all in the same position and were able to share our problems and issues, as well as doing some projects together.' The relationship with the college has continued and Killen now teaches there on a part-time basis, while expanding her range and pitching to new outlets. She is in the middle of a hectic period in her life, making plans for her wedding and searching for a studio space in the part of world to which she feels so connected. 'Yes, I have a lot going on at the moment,' she laughs. 'I was recently invited to exhibit at the British Craft Trade Fair in Harrogate, along with seven other makers from Northern Ireland as part of Craft NI's Export Development Programme. It was a great show for my business, securing orders with new stockists across the UK. I now have five outlets in the north of Ireland and one in a new shop in Kildare Village. Plus I have a dozen or so in England and Wales - and one in Japan. 'The Tory Bush Cottages weekends will be a new challenge for me. Participants will be able to experience the complete process from beginning to end and will make the same things as me. At the end of the weekend, everyone will take away their own bespoke bottle that they will have made and decorated - just the same as mine. 'The cottages are right in the middle of the Mournes. It’s a magical place, a really creative environment, where people will be able to switch off and try something new. If I could find a studio around there, I’d be very happy.' The country traditions of her home patch provided the backdrop to Killen’s earliest exhibited work. For her final year show at the art college, she produced a series of plates based on Downshire Pottery, the oldest pottery in Northern Ireland, which was set up in the 1700s. They, in turn, prompted her to develop the more commercial range, which is now proving so successful. It is inspired by the nostalgic blue and white china she grew up with at home, as well as by her own love of all things retro. 'I collect old bottles and vintage things,' she explains. 'I remember when we used to get glass milk bottles delivered to the doorstep and those little bottles of milk at school. Their shapes look really great in bone china, especially with different surface patterns that are modern and abstract. The blue and white adds to the sense of nostalgia and reminds me of the past, of growing up in this special place.' Tory Bush Cottages Creative Weekends will take place on 13 to 15 May; 24 to 26 June; 2 to 4 September. Places are limited. For more information on how to book visit www.torybush.com. To see more of Rebecca's work go to www.rebeccakillenceramics.com. - See more at: http://www.culturenorthernireland.org/features/crafts/making-it-mournes#sthash.IpSnmoPn.dpuf TagsRebecca Killen Ceramics, Craft, Workshops, Tory Bush Cottages, Culture Northern Ireland, Career, Ceramics SÓ COLLECTIVE AT KILDARE VILLAGE Check out this video from our one of our latest stockists Só Collective, a new store featuring purely Irish design based in Kildare Village. Só Collective is described as a 'unique shopping experience and thoughtful curation of both established and emerging Irish designers. Immersing guests in a rich world of imagery, texture and colour, the space forms an integral part of From the Isle, the exciting new initiative at Kildare Village designed to nurture and support Irish creative talent'. This place is STUNNING a real must see!!! ANOTHER GREAT YEAR IN HARROGATE - BRITISH CRAFT TRADE FAIR 2016 We were delighted to exhibit for second year at the British Craft Trade Fair in Harrogate, this time with a group of 8 designer/makers from Northern Ireland as successful participants on Craft NI's Export Development programme. Take a look at some images from the event including a few new additions to the collection. Please keep an eye on the stockist page to find out where to buy Rebecca Killen Ceramics. TagsRebecca Killen Ceramics, BCTF16, Bone China, British Craft Trade Fair, Handmade, Trade Fair, Harrogate, Craft NI, Export INTERVIEW WITH CRAFT NI Export Profile – The British Craft Trade Fair 2016: Rebecca Killen Ceramics Continuing with our maker interviews ahead of the 2016 British Craft Trade Fair, we're delighted to chat to Rebecca Killen, one of the eight NI makers attending with Craft NI, about her process, her work and her plans for the future. Hi, Rebecca. Tell us a bit about yourself – how did you get into making? I am ceramic designer/maker living and working in County Down creating blue and white bone china products for the interiors and gift ware market. I was first introduced to clay by a very passionate teacher and potter at school and have been using the material ever since. Whilst studying Fine and Applied Art at the University of Ulster I specialised in ceramics and also took a year out to study business at a college in America. After graduating I was keen to combine my making and business skills to create a business in which I could produce and sell a contemporary range of ceramics, so I applied for Craft NI’s making it 2013-2015 programme to help me achieve this goal. Having recently completed the programme I am now selling bottles, vessels and dishes in craft galleries and design boutiques across the U.K. Could you tell us a bit about your making process? I am currently working with bone china, a beautiful material to use. Its smooth and high quality fine finish provides the elegance and delicacy which I use as a foundation for the hand painted decoration. I use the industrial technique of slip casting which involves casting liquid bone china in plaster moulds that I make from turned models or found objects. The surface pattern is then applied, whether it be a hand painted pattern, ceramic decal or dipped cobalt glaze. Each piece is then finished with hints of gold lustre. Every day in the studio is different (one of the reasons why I love what I do) but depending on what deadlines are looming, I could be doing anything from making moulds, hand painting the cobalt designs, glazing to packing and shipping the work. I usually cast first thing every morning to build up stock and the rest of the day is consumed by all the other elements involved in making my work. I allow time during the week to work on the business side of Rebecca Killen Ceramics where I am making calls, answering emails and marketing my products – time-consuming activities but a surprisingly enjoyable part of my business. I am also a part time lecturer at the Southern Regional College and help take a variety of workshops at Mount Ida Pottery, so the weeks tend to be very busy. The process of making is the most enjoyable part of what I do. I wouldn’t exactly say it is relaxing, however when you get into a rhythm there is something strangely satisfying about working with such an unpredictable material. I like to maintain a healthy lifestyle so I try and get to the gym as often as I can, but after being inside the studio most of the week I love to get outdoors at the weekend. I am lucky enough to live in a beautiful part of the country beside the sea and at the foot of the Mourne Mountains so there is plenty to explore. I am also getting married this year so does planning a wedding count as a hobby? Where can people currently see or buy your work? Locally you can find my work in Kiln and Loom and Coppermoon in Belfast, The Kingfisher Craft Gallery, Killyleagh, F.E. McWilliams Gallery, Banbridge and Synergy Studios in Newcastle. My work is also stocked in a range of galleries and design boutiques across the U.K and I have recently sent an order of work to an Irish design shop in Tokyo called Stor. I am excited to be exhibiting some new pieces at the British Craft Trade Fair in Harrogate this April along with 7 other talented maker/designers from Northern Ireland. You can find us at stand 400. Where would you like to see your business in a year's time? Do you have any big plans for 2016? I hope for continued growth of my business, to be fulfilling orders for existing customers but also reaching new markets with my products. I would love to have my work in some larger retailers in the U.K and Ireland this year and also expand on my product list. I am hoping to take part in a couple of major selling events in the U.K and also intend to exhibit at another trade fair (early 2017) to introduce my brand to new audiences. Find out more about Rebecca Killen, as well as her work and details on where to buy it, on the Craft NI Directory. TagsExport, Northern Ireland, Craft, Design, Ceramics, Interview, Craft NI, Rebecca Killen Ceramics, British Craft Trade Fair BRITISH CRAFT TRADE FAIR 2016 After a successful show at the BCTF 2015, we are returning again this year. Find us at stand 400 where we will be exhibiting alongside seven other talented makers from Northern Ireland. 10th - 12th April 2016 TagsRebecca Killen Ceramics, British Craft Trade Fair, BCTF16, Bone China LOCAL TALENT AT SYNERGY STUDIOS We are delighted to be stocking our ceramics in a new exciting project coming soon to Newcastle Co. Down. Synergy Studios, opening this week is a workshop, studio and retail space located at the foot of the Mourne mountains and aims to provide a creative hub for emerging makers, designers and artists. They are hosting a Christmas Pop-Up for the month of December with a festive shopping evening on Friday 4th December A CONTEMPORARY CHRISTMAS We have a collection of vessels, t-lights and bottles on display in Adore Contemporary Boutique for their current exhibition 'A Contemporary Christmas'. Adore is based in the beautiful harbour town of Falmouth, Cornwall and showcases the best of British contemporary craft. Their annual Christmas exhibition sees our work exhibited alongside talented designers; Gemma Scully, Katy Luxton, Bryony Stanford and Fleur Grenier. TagsRebecca Killen Ceramics, Adore Contemporary Boutique, Christmas, Bone China NEW WORK AT COPPERMOON Call into Belfast's best kept secret Coppermoon to see a new batch of Rebecca Killen Ceramics on the shelves including these cute Cobalt Milk & Sugar sets. Coppermoon, a beautiful art and design boutique, showcases collections of jewellery, home and gift products to discerning customers worldwide and supports both local and national designers. Coppermoon have been stocking our products for over a year and we are delighted to launch our new Cobalt Milk & Sugar Sets in store. A beautiful piece for the home or a great gift idea! TagsRebecca Killen Ceramics, Bone China, Milk and Sugar sets, Coppermoon, Belfast HISTORY REPEATING AT THE DOWN ARTS CENTRE During August Craft Month 2015, myself and Áine McKenna showcased our current collections at the Down Arts Centre, Downpatrick in the joint exhibition 'History Repeating'. Both local ceramic designer/makers, we were brought together on Craft NI's 'Making It' programme and have worked successfully together on a number of projects. 'Making It' is a 2 year business start-up programme for makers in craft and applied arts in which participants are placed in host organisations. Áine is based at Down Arts Centre and I at the Southern Regional College. As the 2013/15 programme draws to a close the exhibition showcased a body of work that demonstrated the progress made whilst on the programme, and the challenges of creating a commercial product range alongside conceptual ceramic art. 'History Repeating' makes reference to common themes embedded in both our work as we explored the notion of multiples and industrial processes. Images - Opposite Page Photography History Repeating - Down Arts Centre Rebecca Killen Ceramics - Cobalt Wall Dishes Rebecca Killen Ceramics - Cobalt Bottles Rebecca Killen Ceramics - Cobalt Milk & Sugar Set Rebecca Killen Ceramics - Cobalt and Willow Vessels Rebecca Killen Ceramics - Cobalt Vessels Rebecca Killen Ceramics - Cobalt Dishes Áine McKenna Ceramics To accompany the exhibition Áine and I carried out two workshops where we demonstrated the processes involved in each of our practices. Áine presented the process of handbuilding using fine sheets of paper clay creating porcelain envelopes and bags and I demonstrated how I make my bone china bottles, dishes and vessels using the slip casting technique. We would like to thank all those who have visited our exhibition, the Down Arts Centre, the Arts Council of Northern Ireland, Southern Regional College, Craft NI and Opposite Page Photography without their support ‘History Repeating’ would not have been possible. 'History Repeating' runs until Saturday 29th August at the Down Arts Centre, 2-6 Irish Street, Downpatrick. I have recently become a little bit obsessed with Instagram, after a couple of technical issues (I apologise for my persistent follows) I finally got my @rebeccakillenceramics__ account up and running and I have found so many amazing new artists, designers and inspirations. There are some incredible feeds out there, here are my two favourites (sorry both ceramics, I'm obsessed with that too): @tortus_copenhagen - Totally incredible images of the most beautiful handmade ceramic wares, a real insight into his studio and really cool videos of him throwing pots. I have to stop myself from liking every single image #number1stalker @amandadugganceramics - Clearly inspired by surface, her feed is beautifully composed with an obvious translation between everyday textures and her stunning minimalist ceramic work. And please feel free to follow @rebeccakillenceramics__ where I share daily images of finished pieces and the processes involved in creating contemporary ceramics
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A Bicycle Benefits sticker advertises the discounts program on the door of Daily Groceries Co-op on Prince Avenue. Participants have to show their $5 Bicycle Benefits sticker in order to take advantage of the deals presented by businesses around Athens. (Photo/Sofi Gratas) Sofi Gratas Bikers in Athens can receive discounts at participating businesses through Bicycle Benefits Sofi Gratas | City News Editor Athens businesses partnering with Bicycle Benefits Fuzzy's Taco Shop Ben's Bikes Hendershot's Marti's at Midday Dondero's Kitchen Maepole Sips Espresso Cafe Ike & Jane The Hub Bicycles Zombie Coffee and Donuts Taziki's Mediterranean Cafe Flicker Theatre & Bar Half-Moon Outfitters Avid Bookstore Big City Bread Ted's Most Best Georgia Cycle Sport Mama's Boy Restaurant Active Climbing Agua Linda Taqueria Southern Brewing Company Akademia Brewing In the frigid, dry conditions that constitute a Georgia winter, cyclist sightings in Athens are more sparse than usual. While forlorn tricycles and bicycles have remained in the garage, discounts for their riders are on the up and up. Bicycle Benefits, a national program that aims to maximize alternative transportation, first made its Classic City debut at Daily Groceries Co-op on Prince Avenue in November. Since then, the program has grown to 24 total participating businesses, including Fuzzy's Taco Shop, Avid Bookshop and Mama's Boy. “Overall I’d like to see all the businesses in any given community support Bike Benefits and alternative transportation, and the general public to become more educated on the cost that a business is incurring for automobiles,” Bicycle Benefits founder Ian said. Here’s how it works: Anyone with a Bicycle Benefits sticker on their bicycle helmet can enjoy discounts and deals at participating businesses. These businesses sell stickers for $5 and split the revenue 50-50 between their business and Bicycle Benefits. “We don’t actually expect a huge benefit for us. We are purely encouraging biking—that’s it." -- Luke Gamblin, Half-Moon Outfitters staff member Businesses interested in joining the program have the responsibility of purchasing and selling stickers and “actively” promoting the program through signage, all provided by Bicycle Benefits. Other than a potential influx of bike riding customers, businesses receive no benefits themselves. “We don’t actually expect a huge benefit for us,” said Half-Moon Outfitters staff member Luke Gamblin. “We are purely encouraging biking, that’s it. And that’s what Ian is selling.” It’s an idealistic concept bred from Klepetar’s desire to get more people on two wheels. The program came into existence about 10 years ago, growing extensively in the northeast and in outdoor-oriented cities in the northwest. Georgia has yet to catch on, with Athens being the only participating city as of now. “I think it will absolutely catch on,” Athens resident Nathan Sheets said. Sheets, a Bicycle Benefits member, said he typically frequents Hendershot's and Daily Groceries with his sticker-embellished helmet in hand. He admits he’s one of a few patrons who actively uses discounts offered by the program. Growing and goal-setting Klepetar, originally from New York, saw potential in the Athens cycling community and the local business scene during his search for an expansion of his vision. He said since December, his focus has been spreading the word in hopes of further community involvement. “This is the first year, and the program will grow organically,” Klepetar said. “The goal would be to get better support from BikeAthens and local riding groups.” Klepetar said his team avoids spending money on advertising and instead relies on word-of-mouth. Percent of Athens commuters bike, according to the League of American Bicyclists “We don’t want to program to survive in communities where it’s not welcome,” he said. If it catches on, the foundation for a cycling-centric program to thrive is arguably in existence. In 2016, Athens-Clarke County was ranked in the bronze category — behind its higher rankings of silver and gold — by the League of American Bicyclists “Bicycle Friendly Community” database, with rankings lasting four years. According to ACC’s “report card,” about 1.7 percent of commuters use a bike. The city has been making noteworthy strides since then for its cycling community. In October 2018, the ACC Mayor and Commission unanimously approved the Athens in Motion Bicycle and Pedestrian Master Plan. The TSPLOST-funded plan paves the way for the development of further connectivity, construction and improvements all benefitting a more bike-friendly community. A total of 17 projects were approved with the plan, including the improvement of bike corridors and implementation of sidewalks. In addition to support from local government, Klepetar believes targeting wallets is a convincing way to boost involvement. “Providing a financial benefit on the spot can often be the difference between a person biking and not biking,” Klepetar said. General Manager of Daily Groceries, Kara Brown, said the decision to participate in Bicycle Benefits stemmed from similar ideals. “We were looking to expand our community outreach, also part of our mission is sustainability and looking to help the bike culture in Athens thrive,” Brown said. “Customers get really excited about it. I’m all for promoting biking and alternate transportation over cars. Also just anything to make us a destination for customers.” Daily Groceries offers a 5 percent discount on all purchases, including alcohol. Brown says she’s noticed medium traffic from Bicycle Benefits members. In contrast, employee at Zombie Coffee and Donuts, Liz Woodard, said she hasn’t had a single program participant come into the shop and take advantage of their deal: one free donut with the purchase of any drink. Woodard and her manager, Chelsey Beck, agree sugary donuts and a traffic-heavy downtown location may not be the most enticing for cyclists, resulting in low participation. Optimism through opposition For businesses that may not feel connected to the cycling community, Klepetar tries to promote the value of slowly reducing automobile traffic. When businesses offer free parking, it encourages driving. More driving means more traffic as well as no change or even an increase in environmentally harmful emissions. Klepetar argues providing benefits for drivers, although the status-quo, is “the opposite direction that our communities need to go.” Companies like Bicycle Benefits face another form of opposition. Unless a business’s ideals line up with promoting alternative transportation, there’s no reason to offer discounts with nothing in return. At this point, the program is small. Whether it grows depends on businesses involved as well as Klepetar’s persistence. However, most agree that springtime around the corner will encourage more people to dust off their bikes. Daily Groceries will be heavily promoting their involvement in the program as soon as the weather gets warmer in hopes of attracting more customers. Klepetar is optimistic no matter the odds. “I see Bicycle Benefits as a tool to interject in a person's life,” Klepetar said. “If they have a bicycle and they don’t use it, even if we’re able to change on a personal level a couple trips a week, then it’s been a successful campaign.” BikeAthens teaches how to fix bicycles and donate to those who need transportation Soft music and conversation fill the interior of BikeAthens, already cluttered with bicycles… Members of UGA, Athens biking community promote safety for pedestrians, bikers UGA hosted a Bike & Pedestrian Safety Day to teach the do's and dont's of safety on the roads. The Red & Black News & Brews: Breaking down President Moreheads' State of University, downtown business updates and more Welcome back to The Red & Black's News & Brews, a weekly recap of Athens and Univers… Mayor and Commission votes to repave Barnett Shoals lane reconfiguration, reconsiders Athens in Motion bike plan As voters across the state were finishing up at the polls in the 2018 midterm election, the … Top Athens-Clarke County commission decisions that matter for 2019 As the Athens-Clarke County Commission prepares for a shift in members and initiatives, the results of some decisions from last year are beginning to take effect from extended alcohol sales on St. Patty's Day to free parking on certain federal holidays. Bus stop improvements, Firefly Trail discussed by TSPLOST Citizens Oversight Committee A proposal to increase bus stop infrastructure across Athens was discussed at the TSPLOST Ci… Athens-Clarke County TSPLOST raises sales tax one percent University of Georgia students might have had to dig around for a few extra cents for their … Traffic calming program and bicycle lane improvements discussed at weekly SPLOST meeting The Citizens Advisory Committee is currently faced with 88 potential projects. The CAC is tasked with narrowing down the projects to submit a final list of proposed projects to the Athens-Clarke County Mayor and Commission in July. What'll ya build? Plan paves way for redevelopment near The Varsity, preserves historic homes On the block containing The Varsity, zoning changes have opened up the possibility for redevelopment ranging from demolition of the restaurant to small-scale construction in the surrounding area. ESP holds Big Hearts pageant with baseball league on its mind The Big Hearts event serves as a major fundraiser for the Athens special needs support organization. The event consisted of a silent auction, a pageant and a banquet. Piggly Wiggly coming to Prince Avenue near downtown Athens Piggly Wiggly is setting up shop in the Classic City, filling the grocery-store void in Downtown Athens for years to come. The grocery store in a planned development on Prince Avenue was confirmed as a Piggly Wiggly by Athens-Clarke County Mayor Kelly Girtz and District 6 Commissioner Jerry NeSmith on Feb. 28. Dining Services installs vertical gardening systems at Oglethorpe House In the fall, the vertical aeroponic system was tested at Bolton, and the Tower Gardens were installed at O House on Feb. 12. Cedar Creek solar panels part of push for a greener Athens In the long run, the Cedar Creek solar array is estimated to save consumers money by reducing overall electricity costs for the community. Athens Clarke Bicycle Benefits Ian Klepetar Klepetar Georgia soccer announces 2019 schedule Georgia Museum of Art hosts first Art Heist on Saturday night
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Where Can I Find a List of the Endangered Species? The World Wildlife Fund, the U.S. Fish and Wildlife Service and Earth's Endangered Creatures all offer continually updated lists of endangered and other threatened species. Lists of local endangered are also available fr... More » www.reference.com › Science › Environmental Science What Are Some of the Animals on the Endangered Species List? Some animals that are included on the endangered species list are the western lowland gorilla, the leatherback turtle and the Amur leopard. As of 2015, these animals are categorized as critically endangered by the Intern... More » www.reference.com › Pets & Animals › Animal Reproduction Is the Moose on the Endangered Species List? The moose is not on the Endangered Species List as of April, 2014.. However, in some areas, the moose population has dropped significantly. In Minnesota, the population dropped in 2013 from 4,000 to fewer than 100. More » www.reference.com › Science › Biology › Zoology Why Are Arctic Wolves Endangered? The Arctic wolf species is not endangered, and it is actually listed under "Least Concern" on the International Union for Conservation of Nature status list, as reported by the World Wildlife Fund. The Arctic wolf is not... More » www.reference.com › Pets & Animals › Mammals › Wolves What Laws Protect Endangered Species? As of 2015, the Endangered Species Act contains the laws that protect endangered species, explains the U.S. Fish and Wildlife Service. This legislation gives the federal government the ability to define a species as thre... More » www.reference.com › Government & Politics › Law What Is the Difference Between the Terms Biosphere and Community? In ecology, a community refers to a grouping of species living collectively and interactively with the environment in a specified area, while the term biosphere refers to the total extent of all of the ecological systems... More » Why Are Tree Kangaroos Endangered? The World Wildlife Fund reports that tree kangaroos are endangered due to hunting and habitat loss. Tree kangaroos are indigenous to Indonesia, Papua New Guinea and Australia. More » www.reference.com › Pets & Animals › Mammals › Marsupials Today's Top 10 Articles in science Why Do We Need Rain? How Long Does It Take for Leather to Decompose? What Are the Effects of Ozone Depletion? What Is the World's Most Dangerous Tree? What Is Maximum Sustainable Yield?
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Student’s heart set on Regent’s after Open Day British student Jessica Amado is celebrating securing a place to study Business and Management at Regent’s University London. The 18-year-old who studied A levels at Channing School in Highgate, London, fell in love with the University after an Open Day visit and said she was ‘thrilled’ to be joining the University this September. 'I went to an Open Day at the University and the lecturers were incredibly enthusiastic. They used an electronic voting app to gauge our opinions on different issues during the business talk and really got all of us involved,' Jessica said. She was struck by the campus, location and the small family atmosphere: 'Regent’s campus is beautiful and the tour was very reassuring as the University is quite small, like my school, and its location is second-to-none.' Jessica isn’t the only one who is excited about her future studies - her mother Adrienne, studied Psychology at Regent’s. 'My parents are thrilled that I’ll be following in her footsteps,' said Jessica. Regent’s offers a world-class business education delivered in a cosmopolitan, multilingual and dynamic learning environment. Our practical and international approach to business and management will help you to navigate the global business world. BoE Governor Mark Carney discusses Leadership in a Disruptive Age Bank of England Governor Mark Carney has given an inspiring speech to students at Regent’s. Turkish Migration Conference 2014 a success Turkish Migration Conference: Comparative Perspectives and Continuities held between 30 May and 1 June 2014 was a great success. Regent’s announces major collaboration to boost remittances research Regent’s and global money transfer company Ria Financial sign a major five year collaboration agreement. Dr Stéphane Vinolo's book is published in Brazil Book by Regent's lecturer looks at solution to the violence generated by desires. Chinese food consumers' country of origin preferences Dr Keith Walley of Harper Adams University has shared his insights from recent research on Chinese food consumers and country of origin effects in an RCTS seminar. Transparency ‘footprints’ of central banks Regent's lecturer examines the discrepancy between academics and market participants regarding the transparency of central banks.
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Note: this box searches only for keywords in the titles. For full-text searches, use our search page. Sorry, we don't have an article for that keyword! Note: the article keyword search field and some other of the site's functionality would require Javascript, which however is turned off in your browser. Ultraviolet Optics Suppliers for ultraviolet optics The RP Photonics Buyer's Guide contains 53 suppliers for ultraviolet optics. Find more supplier details at the end of the encyclopedia article, or go to our List of suppliers for You are not yet listed? Get your entry! Acronym: UV optics Definition: optical elements for use with ultraviolet light German: Ultraviolett-Optik Category: general optics How to cite the article; suggest additional literature Ultraviolet light behaves in many ways just as visible light, and it can thus in principle be used with the same times of optical elements as visible or near-infrared light: focusing and imaging lenses, mirrors, optical windows, beam splitters, prisms, polarizers, waveplates, optical filters etc. UV mirrors and lenses are also available in aspheric versions, and anti-reflection coatings are available. However, there are certain special aspects to be observed for applications in the UV region: The bandgap energy is what limits the transparency of a material for UV light. Transparency range: Many optical media which are transparent for visible light become strongly absorbing when one penetrates the ultraviolet spectral region with optical wavelengths below 400 nm. This is essentially because the photon energy then becomes comparable to the band gap energy; a single photon is then sufficient for exciting a carrier from the valence band to the conduction band. Therefore, transparency in the ultraviolet spectral region can be obtained only with dielectric media having a relatively large bandgap. Examples are certain crystalline optical materials like CaF2 and some borates. Even if the bandgap energy of a medium is large enough, there may be substantial UV absorption due to impurities. For really short wavelengths (EUV), there are no suitable transparent media anymore, and one is limited to reflective optics (see below). Below about 200 nm wavelength, even air becomes absorbing, so that UV systems for far-UV light need to be evacuated. Scattering effects are very strong in the UV! Particularly high surface qualities are needed to minimize them. Scattering: Due to the very short wavelengths, ultraviolet light experiences strong scattering even at very tiny imperfections such as scratches on optical services or inhomogeneities within a medium. For example, scattering at very small (sub-wavelength) particles scales with λ−4, getting dramatically stronger for shorter wavelengths. Therefore, a particularly high optical quality of components is required to keep potentially detrimental processes like scattering and beam distortions under control in the ultraviolet. Important material parameters for UV applications are a low bubble and inclusion content, good homogeneity of the refractive index, a small parasitic birefringence. Further, materials should have the potential for polishing surfaces with very small roughness. Damage and degradation problems are quite common for ultraviolet laser devices. Damage and degradation: Particularly for applications with intense UV lasers, the risk of laser damage and of long-term degradation (solarization) is also important. Various media are known to exhibit significant degradation effects – for example, absorption or scattering losses increasing with time during UV radiation –, but some are relatively tolerant against UV light. The optical damage threshold of materials is often substantially lower in the UV than for longer wavelengths, because lower-order absorption processes (e.g. two-photon absorption) are sufficient to bridge the bandgap. Damage and degradation phenomena can strongly depend on certain impurities in the material and on the details of the optical surface finishing. Note also that any optical surfaces can be degraded e.g. if vapors from lubrication oils get into an intense ultraviolet beam, where certain substances are chemically decomposed and can consequently form absorbing coatings on nearby materials. Dispersion effects: In the ultraviolet spectral region, many media exhibit substantially stronger chromatic dispersion than in the visible or infrared region. This must be observed, for example, when using lenses for focusing broadband ultraviolet light. Using achromatic optics can then be particularly important. Examples for UV-transparent Media UV optics are often made from highly purified calcium fluoride (CaF2), which has a very low UV absorption, high homogeneity, low birefringence, relatively high hardness (compared with other fluoride materials), high physical stability, and high optical damage threshold. It can be used down to ≈ 160 nm and is thus suitable for use, e.g., with argon fluoride (ArF) excimer lasers. However, it is brittle, naturally anisotropic, and hygroscopic. Similar properties are obtained for other purified fluorides such as magnesium fluoride (MgF2) and lithium fluoride (LiF). In addition to good UV transparency, such fluorides also offer good infrared properties up to wavelengths of 5 μm and beyond. As an alternative, UV-grade fused silica can be used even for wavelengths down to ≈ 200 nm, whereas the cheaper standard-grade fused silica has significant attenuation already below 260 nm. Similar constraints apply to materials chosen for making dielectric coatings, for example in the form of anti-reflection coatings. A frequently used AR coating material is magnesium fluoride (MgF2). Often, manufacturers offer UV anti-reflection coatings without revealing what material(s) they are made of. Another possible material choice is artificial diamond, which is transparent down to ≈ 230 nm and very robust, but expensive. For nonlinear frequency conversion, one often uses borate crystals such as LBO and BBO, which exhibit relatively good UV transparency and high resistance. Some optical fibers can be used in the near-ultraviolet spectral region, although with relatively high propagation losses. Fiber delivery of ultraviolet light is usually not feasible for shorter wavelengths and/or high optical powers. Common UV Wavelengths In laser technology, a few ultraviolet wavelengths are particularly common: 355 nm is obtained by frequency tripling of Nd:YAG lasers 266 nm is obtained by frequency quadrupling of Nd:YAG lasers 193 nm and a few other wavelengths are made by certain types of excimer lasers. Therefore, certain optical elements like lenses and mirrors are specifically developed for such wavelengths and may then be sold as excimer optics, for example. EUV Optics: Essentially Limited to Reflective Optics In the EUV region, basically all solid materials are relatively strongly absorbing, and even air causes strong attenuation below ≈ 200 nm, so that e.g. lithography with vacuum UV or EUV light below 100 nm has to be performed in vacuum. Bragg mirrors can still be made for the EUV region, e.g. with molybdenum/silicon (Mo/Si) structures, which allow, e.g., ≈ 70% reflectivity at 12 nm wavelength to be reached. Due to this limited reflectivity, EUV optics have to be designed with the smallest possible number of reflecting surfaces. The RP Photonics Buyer's Guide contains 53 suppliers for ultraviolet optics. Among them: EKSMA OPTICS Substrates and finished optical components – windows, lenses and mirrors made from lithium fluoride (LiF), calcium fluoride (CaF2), barium fluoride (BaF2) and sapphire (Al2O3) for laser and optical instruments applications in the UV wavelength range. Laseroptik LASEROPTIK offers excimer optics coatings of various types – anti-reflection (VAR), high reflection (HR), thin-film polarizer (TFP) and variable attenuator (VA). This can be done for many UV wavelengths like 157 nm, 172 nm, 126 nm and others. See also: ultraviolet lasers, optical materials, scattering and other articles in the category general optics © RP Photonics Consulting GmbH All rights reserved worldwide Contact and legal info, declaration of data privacy Resonator Design Software RP Resonator – an extremely flexible resonator design software: script-based definition of resonator structures: arbitrary parametrization calculate all mode properties of interest analyze alignment sensitivities automatic optimization with user-defined figure of merit generation of arbitrary plots Further features: comprehensive documentation (PDF and online) competent technical support Use RP Resonator to drive your resonator design capabilities to perfection! We offer a huge selection of interesting articles on laser technology and photonics. Some examples: Resonator modes in microchip lasers What is different for quasi-three-level lasers? Understanding intensity noise The essential roles of phonons in solid-state lasers Self-starting of passively mode-locked lasers Energy levels of solid-state gain media Data grids for numerical beam propagation Numerical representation of ultrashort pulses These articles belong to our newsletters, which appear about once per month. You will not regret to register!
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Waratahs say victory celebrations "subdued" after an emotional week 20 Apr 2019 Super Rugby by Iain Payten With a big win in a critical derby game, and with oddly rare victories in milestone games for Michael Hooper and Jed Holloway, the Waratahs had every reason to celebrate after beating the Rebels at the SCG. But Waratahs coach Daryl Gibson revealed the NSW dressing shed had been “really subdued” after an emotional week handling - and ultimately overcoming - the tumultuous departure of Israel Folau from their ranks. The Rebels held a 20-7 lead at halftime after dominating the opening 40 minutes but a combination of the Melburnians’ ill-discipline and step-up performances from Bernard Foley and Kurtley Beale saw the Waratahs slowly but surely claw their way back. Through a combination of three penalties, a try and a conversion, Foley scored all of the Waratahs’ 16 points in the second half and with NSW defence holding firm on the other side of the coin, the home side took the victory 23-20. It was the Waratahs’ third win at the SCG, and ensured they stayed in touch with the Rebels on the Australian conference ladder. Dave Wessel’s men missed another chance to kick clear by 11 or 12 points, and instead had to make do with a losing bonus point as they head into their second bye week. The Rebels’ woe was compounded by the sight of star halfback Will Genia limping off with a knee injury, and a possible rib complaint too, but Wessells was optimistic it wasn’t overly serious. For the Waratahs, the victory was proof positive there is life after Izzy. Beale was superb at fullback and along with Foley, the no.15 helped keep immense pressure on the Rebels in their half via the boot. On a slippery night - and with intensity levels at a Spinal Tap level 11 - there was an enormous point of kicking. Sixty-eight kicks came in general play, in fact, as both sides sought to play out of their half. Quade Cooper and Genia did it better in the first half but Foley and crew passed them by in the second, and set up another gritty win on the famous cricket venue. "Overall it was a kick-fest wasn’t it? 68 kicks. Both teams came out with clear game plans to play territory and that conributred rto the game,” Gibson said post-match. "At halftime I said to the boys we’d made two errors off the back of pressure and that was the difference between the two sides. Second half we dominated territory and played very cleverly. "KB was a standout in that regard for us, I thought he kicked very cleverly and he kept the Rebels out of our area which was critical. "And then slowly but surely we fought our way back into that game. I was really pleased with the grit we showed, particularly given the circumstances of the week. "It was a really subdued changing room. It was a weird feeling, given we’d won the game. The boys, the emotion off the week and two come out with a win, it was good. But it was a strange feeling. It has just been an emotional week all around.” Hooper directed his praise toward Foley and Beale, although he was typically strong and made a key turnover at the end of the game when NSW were defending their quarter - and a penalty would have produced a draw. "I sat back at the end of the game and thought that was a real step up from our backline leaders and was really impressive from them to get good control of the game and deliver that for everyone,” he said. “I am really satisfied.” Wessels bemoaned a lack of smarts in the second half, and pointed to the bye week being a welcome one. The Rebels have lost two on the trot. "That’s the story of the game. The first half we really attacked things, we had an attacking mindset, and and the second half we didn’t. It hurts a lot to be honest, that was a game we really wanted to win,” he said. "From an effort point of view our guys were excellent. It feels very different to last week, the effort was there. Things just didn’t go our way in the early part of that second half and we probably didn’t concentrate as much as we should have. "We are at the end of an eight-game block now and we had our travel to Africa in the middle and those kind of things. Because we had a bye in round two, we pretty much didn’t have a week off then either. "So we have been pretty much going since the first ten weeks of the season pretty much continuously. Part of it is guys are pretty tired at the moment. It’s not an excuse but guys mentally were just a bit slower than we needed to be and we got caught on the hop in a few moments.” Waratahs 23 Tries: Ashley-Cooper, Foley Cons: Foley 2 Pens: Foley 3 Rebels 20 Tries: Meakes, Hodge Cons: Cooper 2 Pens: Cooper, Hodge Waratahs Rebels Super Rugby Springboks say logistics behind squad split, star winger ruled out of Johannesburg Test Today at 1:32 AM The Rugby Championship "Crime happens everywhere": Uelese says Tupou theft won't change view of South Africa Yesterday at 6:58 PM The Rugby Championship
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Academicians slammed Facebook's Free Basics initia... Will the World Survive Obama’s Last Year? Why the West Can Never Defeat or “Forgive” Russia The Use of Hemp in India US Federal Ban on Medical Marijuana Silently Lifte... 8 Extraordinary Things Happening in the World Toda... If the United States is Nazified, Eurozone is the ... Humanoid Alien Lands Red UFO in India, Leaves Witn... Our Galaxy Awakens! And Science Confirms It Russia Orders Obama: It's Time To Tell The World A... ET Message: We Are Here Reliance scams Why is a Hate Campaign being Waged against Muslims... Strong Nation The Indian Sage who developed Atomic Theory 2,600 ... Babu-neta-builder nexus killing our cities and peo... Chennai Flood Conspiracy CM pressuring Centre for bauxite clearances: Cong Take tech route to counter ISIL, says scholar 80% of humanity may be implanted with Transhumanis... The judge said organizing such festivals on campus... PROBLEM-REACTION-SOLUTION OR FALSE FLAG Russia Breaks Huge Story: ISIS is Supported by the... Dons still pull the strings in Bollywood We Need Economic System Change Summit, not “Climat... CIA’s Simple Sabotage Field Manual: Guide to Subve... BLACK KNIGHT DECODED Academicians slammed Facebook's Free Basics initiative Academicians from India's premier institutes IITs and IISc have slammed Facebook's Free Basics initiative, terming it “flawed“ and “misleading“. In a joint statement issued on Tuesday, around 50 faculty members from IITs (Bombay, Delhi, Kharagpur, Madras, Patna) and IISc Bengaluru have denounced the proposal dubbing it a “lethal combination that will lead to total lack of freedom on how Indians can use the internet“. Listing three major flaws in the programme, the scientists urged the Telecom Regulatory Authority of India to “thoroughly reject“ Facebook's “free basics“ proposal. “The first obvious flaw in the proposal is that Facebook assumes control of defining what a 'basic' service is.“Facebook will have access to all your apps' contents. “This flaw is not visible to the lay person as it's a technical detail, but it has deep and disturbing implications. Since Facebook can access un-encrypted contents of users' 'basic' services, either we get to consider health apps to be not basic, or risk revealing health records of all Indians to Facebook. “The third flaw is that the term 'free' in 'free basics' is a marketing gimmick.“ The academicians said that the 'Free Basics' proposal “is flawed as above is alarming but not surprising, for it violates one of the core architectural principles of internet design: net neutrality. “Compromising net neutrality, an important design principle of the internet, would invariably lead to deep consequences on people's freedom to access and use information. “We, therefore, urge that the TRAI should support net neutrality in its strongest form, and thoroughly reject Facebook's 'free basics' proposal.“ Dec 31 2015 : The Times of India (Hyderabad) Posted by SATHYA at Thursday, December 31, 2015 No comments: Labels: CONSPIRACIES, GLOBAL POLITICS, GLOBALIZATION, INDIA, MNCs, NATIONAL SECURITY, POLITICAL PONEROLOGY, PRIVATIZATION, PROXY WAR, SOUTH ASIA, SUBVERSION, WEAPONS OF MASS PRESCRIPTION, WORLD SHADOW GOVERNMENT [Editor’s Note: As we come to the close of 2015, it has been an exceptionally busy year for us. Despite the victories against the neoConzies, where we beat them by getting the Iran nuclear scam exposed for what it was — a complete fraud to set the stage for a war against that country — the Obama administration has kept several undeclared wars going. America used the scum of the earth to attack Ukraine, under the black flag of “pursuing our interests” Ukraine had turned into the slam dunk disaster that we forewarned about at the beginning of the Maidan CIA coup. Although all of the hoax claims of Russian aggression have been shot down in flames, no one at the State Department nor the US NATO command, nor the White House, has jumped off a bridge to make some moral restitution to the American people and the world. But even worse, America’s institutions, have stood down completely from standing against the foreign policy insanity. This includes virtually all the veterans associations, where weaning them off their focus on benefits and their love of fluff stuff is like pulling teeth. We find more interest among common citizens for fighting against the political criminals in the US power structure than we do in the military structure, where playing it safe seems to be their top priority. More than a few rubber stamp every aggressive foreign policy announcement with joy, similar to winning a modest lotto. Frankly, they don’t see it as their job. They are philosophically AWOL, and have not suffered any negative publicity for it, so they see no reason to change. The church community is in the same boat… “not our job, man”, despite the huge moral issues at stake, with American foreign policy having become the biggest killer on the planet, and yet there is no real rage. This puts all of us here at home at huge risk — those who are willing to fight — because it is proven that when “they” come for us, we can expect nothing from our American institutions, in terms of fighting back. They will keep their heads down to focus on their own skins, and yet wave tiny flags and chant “God Bless America” on cue whenever asked to… Jim W. Dean ] First published … December 27, 2015 Mr. Hope and Change Why does the world have to be concerned about American politics? The answer is simple, if you are going to die in your home with your family torn to pieces around you, chances are it will be America killing you. Americans are quite aware of this and although the majority don’t approve of America’s insane foreign policy, the right wing Republican Party, the “opposition” not only does, they don’t think Obama is doing enough killing and certainly not in enough places. So, the world is stuck living and dying under the shadow of Washington politics, with Obama’s frightening policies representing the “moderate” point of view and, in the wings a dozen madmen await, promising American armies across Africa and the Middle East, American hegemony in the Far East and nuclear annihilation for anyone who objects. Is this really how it is? The answer, which is a resounding “yes,” is only history repeating itself. You see, best information out there, leaked detailed investigative reports from the US government indicate that 9/11 was staged by an international cabal. Yes, Saudi Arabia was involved. When these documents were sent from Russia in May of 2014, citing not only Saudi Arabia but a very different “cabal” of political and financial leaders — American, Canadian, Israeli and South African, backed by rogue groups in the CIA and Pentagon and backed by Saudi and Israeli intelligence — sent from Russia and published in Veterans Today only (after being refused by CNN), no one heard what they wanted to hear. There were no Islamic extremists, no bin Laden, only the secretive and powerful, names like “Bronfman” or “Netanyahu.” Nobody was hiding in caves, not the real perpetrators, same as today with ISIS, the terror group run from boardrooms in Zurich and London, not from tunnels under Mosul. The four horsemen of the apocalypse Why we take a look at this now is that Bush-era history may well be repeating itself. His brother Jeb is a presidential frontrunner; Donald Trump, a total unknown may be elected as well, and so many others, all working for the shady Koch Brothers and Israeli gambling boss Sheldon Adelson, are looking for a world war. All have one thing in common, war with Russia, a worldwide police state with universal surveillance and what is less understood, environmental collapse that will inexorably lead to world depopulation. What we also need to look at, why I hesitantly mention 9/11 and the proven facts, nuclear weapons planted under the “triple towers,” arrests of Mossad teams across New York, radio jammers that block first responder communications, suspects flown out of the country, two planeloads of Saudis and Israeli…we are seeing it all again. Now it is called “ISIS,” the exact same marriage of Israeli and Saudi intelligence, with Erdogan thrown into the mix, working hand in hand with the CIA and Pentagon, caught over and over commanding ISIS units, supplying their weapons and pouring in cash from what is now exposed by Russia to be a massive oil trade that everyone knew about all along. Not only are the players the same for ISIS but the Ukraine as well, for Boko Harum, for al Shebab in Kenya and East Africa, for the new expanded war in Afghanistan and a new terror war now sweeping across Europe and into the US as well. But then, what does this have to do with American politics? What does it have to do with Obama? Would America survive a third wave of Bushes – from a national security view? Seven years ago, Obama came on the scene addressing world Muslims, offering peace, offering Americans justice and a new direction. In America, Obama’s domestic policies have led to relative economic successes, while Obama and the Democratic Party have fought for worker’s rights, health and education and a return to voting rights. Under Obama’s watch, however, police murders have either increased or have begun being reported after years of silence, we don’t know which is true, the “Arab Springs” have thrown a hundred million people into a political disaster – now clearly a CIA plot – and the Cold War is back on, based on another Mossad/CIA plot in Ukraine. What is, or at least seems to be insane, are the moves in the opposite direction as well, the nuclear agreement with Iran and the recent Syrian accord with Russia, to name a few. Thus, we have Obama and Kerry one moment spouting the most obvious and clumsy lies and following genocidal policies, particularly toward Iran, Syria, Russia and China, while only a short time later coming to the bargaining table with competent and rational initiatives. This is pure schizophrenia. There is no question that Russia has been pushed into drawing a line in Syria against American aggression. Whatever anyone says, particularly how Obama is failing to fight ISIS, those who voice the most concerns about ISIS are those who helped found ISIS and continue to support that terrorist group. We are talking not only Israel, Saudi Arabia and Turkey but America’s Right, the same people who helped stage 9/11 in order to create an atmosphere of fear. As a minor aside, we ask a simple question: “What is the difference between the power mad NSA (National Security Agency) that intercepts world communications and Google Corporation?” The answer to this is simple, “none.” Thus, where in seven years, Obama failed to bring America into the light, pushing the world into a New Cold War and Europe into a period of political insanity not seen since August 1914. The same tired players — the American political gangsters, the McCain and Romney cartel, tied to Mexico’s Salinas family, the Adelson empire out of Macao and the Rothschild-Rockefeller “Federal Reserve Cartel” that controls world currency and banking — wield the real power. This is what we are really seeing, an America ruled at an overt level by scamsters and criminals, oil, defense, insurance, nuclear power and coal, hand in hand with drug cartels and powerful families like the Walton/Walmart group. Behind this, there is no “America” as such, only a thin “front” for channeling military power into the hands of worldwide organized crime, more than “multi-generational,” more like “millennial.” Gordon Duff is a Marine combat veteran of the Vietnam War who has worked on veterans and POW issues for decades and consulted with governments challenged by security issues. He’s a senior editor and chairman of the board of Veterans Today, especially for the online magazine “New Eastern Outlook”. NEO – Tracking ISIS to DC’s Doorsteps NEO: ISIS, a Partner America Can Live With NEO: Obama Plays Foreign Policy Roulette NEO – Trailing ISIS to Tel Aviv NEO – Something Strange About ISIS Posted by SATHYA at Tuesday, December 29, 2015 No comments: Labels: AMERICA, CIA, CONSPIRACIES, FALSE FLAG, FASCISM, GLOBAL POLITICS, ISIS, ISRAEL, KHAZARIAN MAFIA, MOSSAD, NATO, POLITICAL PONEROLOGY, PROXY WAR, SUBVERSION, TERRORISM, WAR IS A RACKET, WORLD SHADOW GOVERNMENT, ZIONISM Knowledge is power. The more knowledge we have, the more informed our choices can be. This is how we become ever better agents of positive transformation in our world. I highly encourage you to find the time to read this profound book at the link below. Or at the very least explore one or more of its chapters using the links to each chapter given in the index below. And please spread the word. This is how we come together to create the world we all know is possible. The free, online book Lifting the Veil is far and above the best summary I've ever seen of all that is going on in our world. Author Timothy Silver masterfully takes us behind the scenes to learn about the hidden forces which dramatically shape world politics and ultimately affect the lives of every one of us. With over 500 footnotes linking directly to reliable sources to verify all that is stated, this amazing piece of excellent research ties together many key threads that the media have failed to cover. It dives deep beneath the surface of historical events to show us the motivating forces and corrupt, elite interest groups which have successfully manipulated world events in a way that rarely gets reported in history books. Chapter I: The War on Terror is a Fraud Chapter II: The One-Party State Chapter III: Psychopathy, Power and Politics Chapter IV: Operation Paperclip Chapter V: MK-ULTRA Chapter VI: Operation Gladio Chapter VII: Operation Mockingbird Chapter VIII: COINTELPRO Chapter IX: The Phoenix Program Chapter X: Iran/Contra Chapter XI: Continuity of Government Chapter XII: The Pedophocracy Chapter XIII: Cults and Child Abuse Chapter XIV: Trauma-Based Mind Control Chapter XV: The Pathocracy Chapter XVI: Solutions Chapter XVII: The Awakening This message is also available online at http://www.WantToKnow.info/mk/best-summary-ever See exceptional archive of revealing news articles. Explore the mind and heart expanding websites managed by the nonprofit PEERS network: www.peerservice.org - PEERS websites: Spreading inspiration, education, & empowerment www.momentoflove.org - Every person in the world has a heart www.personalgrowthcourses.net - Dynamic online courses powerfully expand your horizons www.WantToKnow.info - Reliable, verifiable information on major cover-ups www.weboflove.org - Strengthening the Web of Love that interconnects us all Labels: AMERICA, BANKING SYSTEM, CIA, CONSCIOUSNESS, CONSPIRACIES, CORPORATE CORRUPTION, FASCISM, GLOBAL POLITICS, ISIS, ISRAEL, KHAZARIAN MAFIA, MOSSAD, POLITICAL PONEROLOGY, TERRORISM, TRUTH, WAR IS A RACKET, ZIONISM Historically and intuitively, Russia has fought for the survival of humanity. Of course, things are not always pronounced or defined in such terms. However, already on several occasions, this enormous country has stood up against the most mighty and evil forces that have threatened the very survival of our Planet. During the Second World War, the Soviet people, mainly Russians, sacrificed at least 25 million men, women and children, in the end defeating Nazism. No other country in modern history has undergone more. Right after that victory, Russia, alongside China and later Cuba, embarked on the most awesome and noble project of all times: the systematic dismantling of Western colonialism. All over the world oppressed masses stood up against European and North American imperialist barbarity, and it was the Soviet Union that was ready to give them a beacon of hope, as well as substantial financial, ideological and military support. As one oppressed and ruined nation after another was gaining independence, hatred against the Soviet Union and the Russian people was growing in virtually all the capitals of the Western world. After all, the looting of non-white continents was considered a natural right of the “civilized world”. In the USA and Europe, such words as “colonialism” and “imperialism” were rapidly gaining extremely negative connotations, or at least on the surface. It would have been counter-productive to attack, to demonize the Soviet Union for supporting liberation struggles in all those continents. Instead, elaborate theories about the “Evil Empire” were erected. Russia has always been “ in the way”; a colossal country spoiling the brutal plans of Washington, Berlin, London and Paris – plans to control and plunder the entire planet. But the nobler were its deeds; the more insulting the attacks against it. Russia always possessed tremendous capacity to mobilize itself, to throw all its resources at achieving one single, humanistic, and deeply moral goal. There has been something sacred in its struggles, something “higher”, and totally essential. “Stand up, enormous country, stand up to a deadly fight!” This is how one of the greatest patriotic songs of the Second World War begins. When Russia fights, then all that matters is victory. No price is too high. Fate selected Russia to struggle for the entire world. If you don’t believe in “fate”, you will never understand the “Russian soul”. It is not about religion – Russia is mainly anarchic and “atheist”. But it believes in and accepts fate. Moreover, most of the time Russia has really no choice. It has been faced either with the victory or the end of humanity. And when the world and its survival have been threatened, Russia has always stood up: outraged, frightening but also extremely beautiful in its wrath and determination. It has fought with each pore, each speck of its land, and each heart of its people. It has almost always won, but at a horrific price, burying millions of its sons and daughters, stricken afterwards by indescribable sorrow and pain. And there was never anyone standing by, to console it. As the fires were still raging, as tears were still covering the faces of mothers and wives who lost their loved ones, the country was spat at, ridiculed and humiliated by the Western Machiavellian regimes and their propaganda. Its heroism was belittled, its sacrifice mocked. It was repeated that its millions who died for humankind, actually died in vain. In return for its heroic struggles, Russia never asked for anything, except for two essential things: recognition and respect. It never received either! Now once again, Russia stands up, launching its epic fight against ISIS; that horrendous parody in the Muslim religion – created and armed by the West and its vicious regional lackeys. Russia had to act. Because if it didn’t, who would? After centuries of Western crusades and the most appalling colonialist practices, there is hardly anything left of the Middle East, this marvelous part of the world, which can only be described as one of the cradles of our civilization. Plundered and humiliated, the Middle East has been reduced to a pathetic mosaic of client states, serving the West. Tens of millions have been murdered. Everything has been plundered. Socialist and secular governments have been cornered and overthrown. I have worked intensively in this part of the world, and I can testify that save Africa, there is no other area of the world that is so scarred and brutalized by Western greed and barbarism. Hopeless, mortally injured and desperate, two ancient countries that have been lately suffering the most –Syria and Iraq – approached Russia, asking for its help. And Russia agreed to help them. Yes, of course, I can already hear that cacophony of noises coming from Europe and North America about: “Russian interests” and its “sphere of influence”. Because in the West, nothing is, and nothing can be, sacred. Because everything has to be tinted with dark sarcasm and nihilism… If the West is acting like a thug, then the rest of the world has to be portrayed in the same colors and shades. After all, the West does not have allies, it doesn’t have feelings; only interests. I did not invent this; I was told this, again and again, when I lived and worked in destroyed parts of Africa. But I don’t give a damn what they say in Paris or Washington. What matters is what is said in Iraq, Syria and Lebanon. And I will tell you how it is there: if you go to a barber shop there, and you say that you are Russian, people get up, and they embrace you, and some cry! Russia will never attack other countries, but if attacked, its wrath can be horrendous, especially when it is in the middle of fighting a war. “Whoever will come to us with a sword, from a sward they will perish,” proclaimed Alexander Nevsky, the 13th Century Prince of Novgorod. The recent downing of a Russian bomber over Syria by Turkish Air Forces has increased the danger of a much wider regional war. Turkey, a NATO member nation, is spreading terror all over the region: from Libya and Somalia, to Iraq, Syria and its own Kurdish territory. It is torturing people, murdering many including journalists, robbing millions of their natural resources, and spreading the most extremist, mainly Qatari-backed, jihadi teachings. I met Recep Tayyip Erdoğan, many years ago in the early 1990s in Istanbul, when he was the then mayor of the city, and when I was “licking my wounds” in between my writing on how the West was systematically destroying Yugoslavia. “Do you speak Turkish?” he asked me during one of our meetings. “Not well”, I replied. “Just a little.” “But you know perfectly well how to pronounce the name of our party! That shows how important we are.” From our first meeting, I knew that he was a megalomaniac, a man full of inferiority complexes, and an aggressive scum. I had no idea he would ‘go so far’. He did. Because of him, millions are suffering, all over the region. Now he has shot down a Russian bomber and invaded Iraq. Turkey has fought Russia on several occasions, and almost always lost. Then, in between two world wars, it managed to survive only because of the help provided to it by the Soviet Union. Turkey should think twice about its next steps. Russia does not just ‘fight wars’. Its fights for the survival of mankind are nothing short of an enormous work of art, of poetry or a symphony. It is hard to explain but it is so. Everything is intertwined. To shoot the Russian SU-24 from behind is like shaking those 25 million who died during the Second World War. It is horrendous, as it is unwise. In Russia, this is not how things are done. You want to fight, then come out and fight, face to face. But if you kill like a coward, and if you invade neighboring and already devastated countries, you may, one day, find yourself facing not just some SU-24’s, but a bunch of heavy strategic bombers. Russia cannot be defeated. There are many reasons for it. One is pragmatic: it is a nuclear superpower. Another is, because it usually fights for just causes. And it does so with all its might and with its whole heart. If it were not for Russia, there would be no Planet Earth, at least as we know it. The West and its fascist Christian states would be fully in control of the world. The “un-people”, the “non-whites” would be treated like animals (even worse than they are treated now): there would be no control left, and no boundaries to the theft and destruction. The so-called “civilized world” (the one that builds its theatres and schools from the rivers of blood and corpses of others) would be marching, unopposed, towards absolute control over the Planet. Fortunately, Russia exists. And it cannot be defeated. And it will never be defeated. However, it can also never be forgiven by the West, for standing on the side of the wretched of the earth. Andre Vltchek is philosopher, novelist, filmmaker and investigative journalist, he’s a creator of Vltchek’s World an a dedicated Twitter user, especially for the online magazine “New Eastern Outlook” First appeared: http://journal-neo.org/2015/12/17/why-the-west-can-never-defeat-or-forgive-russia/ Posted by SATHYA at Friday, December 25, 2015 No comments: Labels: AMERICA, BRICS, CHINA, CONSCIOUSNESS, GLOBAL POLITICS, HISTORY, INDIA, NATIONAL SECURITY, RUSSIA 'The white man goes into his church and talks about Jesus; the Indian goes into his tepee and talks to Jesus'. (Quanah Parker) Cannabis or ganja is associated with worship of the Hindu deity Shiva, who is popularly believed to like the hemp plant. Bhang is offered to Shiva images, especially on Shivratri festival. This practice is particularly witnessed at temples of Benares, Baidynath and Tarakeswar. Bhang is not only offered to the deity, but also consumed by Shaivite (sect of Shiva) yogis. Charas is smoked by some Shaivite devotees and cannabis itself is seen as a gift (“prasad,” or offering) to Shiva to aid in sadhana. Some of the wandering ascetics in India known as sadhussmoke charas out of a clay chillum. In Indian tradition marijuana is associated with immortality. The myth of the churning of “Amrita” by Hindu Gods is said to be the making of cosmic ‘Bhang’ (a marijuana drink) . This Amrita is known as the elixir of eternal life. After churning the ocean, the demons attempted to gain control of the Amrita, but the gods were able to prevent this seizure, giving cannabis the name ‘Shudha Vijaya’ meaning ‘Pure Victory’. According to one description, when the elixir of life was produced from the churning of the ocean by the devas and the asuras, Shiva created cannabis from his own body to purify the elixir (whence, for cannabis, the epithet angaja or body-born). Another account suggests that the cannabis plant sprang when a drop of the elixir dropped on the ground. Thus, cannabis is used by sages due to association with elixir and Shiva. Wise drinking of bhang, according to religious rites, is believed to cleanse sins, unite one with Shiva and avoid the miseries of hell in the after-life. In contrast, foolish drinking of bhang without rites is considered a sin. Early Indian legends maintained that the angel of mankind lived in the leaves of the marijuana plant. It was so sacred that it was reputed to deter evil and cleanse its user of sin. In Hindu mythology hemp is a holy plant given to man for the “welfare of mankind” and is considered to be one of the divine nectars able to give man anything from good health, to long life, to visions of the gods. Nectar is defined as the fabled drink of the gods. Tradition also maintains that when the nectar or Amrita dropped from heaven, cannabis sprouted from it. According to legend, Lord Siva, the Supreme God of many Hindu sects, had some family squabble and went off to the fields. He sat under a hemp plant so as to be sheltered from the heat of the sun and happened to eat some of its leaves. He felt so refreshed from the hemp plant that it became his favorite food, and that is how he got his title, the Lord of Bhang. Cannabis is mentioned as a medicinal and magical plant as well as a “sacred grass” in the Atharva Veda (2000 B.C.) which releases us from anxiety and refers to hemp as a “source of happiness”, “joy-giver” and “liberator”. It has been venerated and used as a sacrifice to the Gods. Indian Tradition, writing, and belief is that the “Siddhartha” (the Buddha), used and ate nothing but hemp and its seeds for six years prior to announcing (discovering) his truths and becoming the Buddha. Fifteenth-century documents refers to cannabis as endowing light-heartedness, joy and rejoice, and claimed that among its virtues are “astringency”, “heat”, “speech-giving”, “inspiration of mental powers”, “excitability” and the capacity to “remove wind and phlegm”. Among fakirs (Hindu and Muslim Ascetics) bhang is viewed as the giver of long life and a means of communion with the divine spirit. Like his Hindu brother, the Muslim fakir reveres bhang as the lengthener of life and the freer from the bonds of self. Shirdi Sai Baba, a well renowned Saint used to smoke hemp in a chillum (pipe); this chillum is believed to have magical and spiritual attributes. According to the Encyclopedia Britannica, the section on “mysticism”: “The Vedas (Hindu sacred writings) are hymns to the mystic fire and the inner sense of sacrifice, burning forever on the 'altar Mind’. Hence the abundance of solar and fire images: birds of fire, the fire of the sun, and the isles of fire. The symbol system of the world’s religions and mysticisms are profound illuminations of the human-divine mystery. Be it the cave of the heart or the lotus of the heart, 'the dwelling place of that which is the Essence of the Universe, "the third eye”, or the eye of wisdom’ - the symbols all refer back to wisdom entering the aspiring soul on its way to progressive self-understanding. 'I saw the Lord with the Eye of the Heart. I said, “Who art thou?” and he answered, “Thou”’.“ The ancient Indian mystics said, ”…that in the ecstasy of bhang (marijuana) the spark of the Eternal in man turns into light the murkiness of matter or illusion and the self is lost in the central soul fire. Raising man out of himself and above mean individual worries, bhang makes him one with the divine force of nature and the mystery 'I am he’ grew plain. (Taken from the Indian Hemp Drugs Commission Report which was written at the turn of the twentieth century.) In the early 20th Century AD, the Indian Hemp Drugs Commission set up to study the use of hemp in India contains the following observations : “…Bhang is the Joy-giver, the Sky-filler, the Heavenly- Guide, the Poor Man’s Heaven, the Soother of Grief…No god or man is as good as the religious drinker of bhang…The supporting power of bhang has brought many a Hindu family safe through the miseries of famine. To forbid or even seriously restrict the use of so gracious an herb as the hemp would cause widespread suffering and annoyance and to large bands of worshipped ascetics, deep-seated anger. It would rob the people of a solace on discomfort, of a cure in sickness, of a guardian whose gracious protection saves them from the attacks of evil influences…” . I find it so ironic that the British Raj didn’t attempt any prohibition on the plant so as not to hurt the sentiments of the Indian people; The plant was later prohibited much later, by our own Indian Government, post Indian Independence! According to Earnest Abel in "Marijuana - The First Twelve Thousand Years - 6” , the Sikh community in India used hemp as Sukhnidhan, sometimes referred to as Bhang, is a war beverage, first created and prepared by Guru Gobind Singh, consisting of a mixture of water, almond nuts, milk and cannabis. Narrated by many Sikh, Muslim, Hindu and Persian native accounts, the Singhs used Sukhnidhan and consumed Sukhnidhan daily. The Indian Hemp Drugs Commission Report describes the traditional use of cannabis in the Sikh religion. “Among the Sikhs the use of bhang as a beverage appears to be common, and to be associated with their religious practices. The witnesses who refer to this use by the Sikhs appear to regard it as an essential part of their religious rites having the authority of the Granth or Sikh scripture. Witness Sodhi Iswar Singh, Extra Assistant Commissioner, says :“As far as I know, bhang is pounded by the Sikhs on the Dasehra day, and it is ordinarily binding upon every Sikh to drink it as a sacred draught by mixing water with it. Legend–Guru Gobind Singh, the tenth guru, the founder of the Sikh religion, was on the gaddi of Baba Nanak in the time of Emperor Aurangzeb. When the guru was at Anandpur, tahsil Una, Hoshiarpur district, engaged in battle with the Hill Rajas of the Simla, Kangra, and the Hoshiarpur districts, the Rains sent an elephant, who was trained in attacking and slaying the forces of the enemy with a sword in his trunk and in breaking open the gates of forts, to attack and capture the Lohgarh fort near Anandpur. The guru gave one of his followers, Bachittar Singh, some bhang and a little of opium to eat, and directed him to face the said elephant. This brave man obeyed the word of command of his leader and set out on horse back with his shield and spear to attacked the elephant, who was intoxicated and had achieved victories in several battles before, with the result that the animal was overpowered and the Hill Rajas defeated. The use of bhang, therefore, on the Dasehra day is necessary as a sacred draught. It is customary among the Sikhs generally to drink bhang, so that Guru Gobind Singh has himself is said to have said the following poems in praise of bhang: "Give me, O Saki (butler), a cup of green colour (bhang), as it is required by me at the time of battle. "Bhang is also used on the Chandas day, which is a festival of the god Sheoji Mahadeva. The Sikhs consider it binding to use it on the Dasehra day-The quantity then taken is too small to prove injurious.” As Sikhs are absolutely prohibited by their religion from smoking, the use of ganja and charas in this form is not practised by them. of old Sikh times, is annually permitted to collect without interference a boat load of bhang, which is afterwards. distributed throughout the year to the sadhus and beggars who are supported by the dharamsala. Sukhnidhan is offered as a holy drink or Kara Parshad to all visitors in a Gurdwara. This is regarded as food blessed by the Guru and should not be refused.” By the sixteenth century A.D., it found its way into India’s popular literature. The Dhurtasamagama, or “Rogue’s Congress”, a light farce written to amuse audiences, has two beggars come before an unscrupulous judge asking for a decision on a quarrel concerning a maiden at the bazaar. Before he will render his decision, however, the judge demands payment for his arbitration, In response to this demand, one of the beggars offers some bhang. The judge readily accepts and, tasting it, declares that “it produces a healthy appetite, sharpens the wits, and acts as an aphrodisiac”. In the Rajvallabha, a seventeenth-century text dealing with drugs used in India, bhang is described as follows: “India’s food is acid, produces infatuation, and destroys leprosy. It creates vital energy, increases mental powers and internal heat, corrects irregularities of the phlegmatic humor, and is an elixir vitae. It was originally produced like nectar from the ocean by churning it with Mount Mandara. Inasmuch as it is believed to give victory in the three worlds and to bring delight to the king of the gods (Siva), it was called vijaya (victorious). This desire-filling drug was believed to have been obtained by men on earth for the welfare of all people. To those who use it regularly, it begets joy and diminishes anxiety.” Cannabis was also an important part of the Tantric religious yoga sex acts consecrated to the goddess Kali. During the ritual, about an hour and a half prior to intercourse the devotee placed a bowl of bhang before him and uttered the mantra: “Om hrim, O ambrosia-formed goddess [Kali] who has arisen from ambrosia, who showers ambrosia, bring me ambrosia again and again, bestow occult power [siddhi] and bring my chosen deity to my power.” Then, after uttering several other mantras, he drank the potion. The delay between drinking the bhang and the sex act was to allow the drug time to act so that it would heighten the senses and thereby increase the feeling of oneness with the goddess. There are three types of cannabis used in India. The first, Bhang, consists of the leaves and plant tops of the marijuana plant. It is usually consumed as an infusion in beverage form, and varies in strength according to how much Cannabis is used in the preparation. The second, Ganja, consisting of the leaves and the plant tops, is smoked. The third, called Charas, consists of the resinous buds and/or extracted resin from the leaves of the marijuana plant. Typically, Bhang is the most commonly used form of cannabis in religious festivals. Labels: AWAKENING, CONSCIOUSNESS, ILLUSION AND REALITY, LIBERALIZATION, TRUTH US Federal Ban on Medical Marijuana Silently Lifted One of the bills secretly tucked into the 1,603-page $1.1 Trillion Spending Bill is the federal government’s lifting of the decades old ban on medical marijuana. This should pave the way for the removal of marijuana restrictions in other countries, too. Not to spoil the fun, but the other bill that’s been secretly passed alongside the spending bill is CISA, giving them the legal framework to continue metadata gathering on every US citizen’s internet activities. CISA Quietly Passed by Congress thru Sleight of Hand There could be a bigger picture that must be considered here. We will discuss them in the next few days. In the meantime, do enjoy the holidays. Mabuhay, Marijuana! Congress quietly ends federal government’s ban on medical marijuana Tucked deep inside the 1,603-page federal spending measure is a provision that effectively ends the federal government’s prohibition on medical marijuana and signals a major shift in drug policy. The bill’s passage over the weekend marks the first time Congress has approved nationally significant legislation backed by legalization advocates. It brings almost to a close two decades of tension between the states and Washington over medical use of marijuana. Under the provision, states where medical pot is legal would no longer need to worry about federal drug agents raiding retail operations. Agents would be prohibited from doing so. The Obama administration has largely followed that rule since last year as a matter of policy. But the measure approved as part of the spending bill, which President Obama plans to sign this week, will codify it as a matter of law. Pot advocates had lobbied Congress to embrace the administration’s policy, which they warned was vulnerable to revision under a less tolerant future administration. More important, from the standpoint of activists, Congress’ action marked the emergence of a new alliance in marijuana politics: Republicans are taking a prominent role in backing states’ right to allow use of a drug the federal government still officially classifies as more dangerous than cocaine. “This is a victory for so many,” said the measure’s coauthor, Republican Rep. Dana Rohrabacher of Costa Mesa. The measure’s approval, he said, represents “the first time in decades that the federal government has curtailed its oppressive prohibition of marijuana.” By now, 32 states and the District of Columbia have legalized pot or its ingredients to treat ailments, a movement that began in the 1990s. Even back then, some states had been approving broader decriminalization measures for two decades. The medical marijuana movement has picked up considerable momentum in recent years. The Drug Enforcement Administration, however, continues to place marijuana in the most dangerous category of narcotics, with no accepted medical use. Congress for years had resisted calls to allow states to chart their own path on pot. The marijuana measure, which forbids the federal government from using any of its resources to impede state medical marijuana laws, was previously rejected half a dozen times. When Washington, D.C., voters approved medical marijuana in 1998, Congress used its authority over the city’s affairs to block the law from taking effect for 11 years. Even as Congress has shifted ground on medical marijuana, lawmakers remain uneasy about full legalization. A separate amendment to the spending package, tacked on at the behest of anti-marijuana crusader Rep. Andy Harris (R-Md.), will jeopardize the legalization of recreational pot in Washington, D.C., which voters approved last month. Marijuana proponents nonetheless said they felt more confident than ever that Congress was drifting toward their point of view. “The war on medical marijuana is over,” said Bill Piper, a lobbyist with the Drug Policy Alliance, who called the move historic. “Now the fight moves on to legalization of all marijuana,” he said. “This is the strongest signal we have received from Congress [that] the politics have really shifted. … Congress has been slow to catch up with the states and American people, but it is catching up.” The measure, which Rohrabacher championed with Rep. Sam Farr, a Democrat from Carmel, had the support of large numbers of Democrats for years. Enough Republicans joined them this year to put it over the top. When the House first passed the measure earlier this year, 49 Republicans voted aye. Some Republicans are pivoting off their traditional anti-drug platform at a time when most voters live in states where medical marijuana is legal, in many cases as a result of ballot measures. Polls show that while Republican voters are far less likely than the broader public to support outright legalization, they favor allowing marijuana for medical use by a commanding majority. Legalization also has great appeal to millennials, a demographic group with which Republicans are aggressively trying to make inroads. Approval of the pot measure comes after the Obama administration directed federal prosecutors last year to stop enforcing drug laws that contradict state marijuana policies. Since then, federal raids of marijuana merchants and growers who are operating legally in their states have been limited to those accused of other violations, such as money laundering. “The federal government should never get in between patients and their medicine,” said Rep. Barbara Lee (D-Oakland). [email protected] Twitter: @evanhalper http://www.latimes.com/nation/la-na-medical-pot-20141216-story.html One of the significant sources of funds for the fascist Nazionist Jesuit Khazarian Mafia is the healthcare industry which registered a whopping $3.09 trillion in 2014, and is projected to soar to $3.57 trillion in 2017, in the US alone. We can help take down the Dark Cabal by avoiding drugs, defeat any viral attack and scaremongering easily by knowing how to build our own comprehensive antiviral system. Find more about it here. Posted by SATHYA at Friday, December 25, 2015 1 comment: Labels: AMERICA, AWAKENING, CONSCIOUSNESS, ILLUSION AND REALITY, LIBERALIZATION, TRUTH 8 Extraordinary Things Happening in the World Today Most of us haven’t quite realized there is something extraordinary happening. A few months ago I freed myself from standard-procedure society, I broke the chains of fear that kept me locked up into the system. Since then, I see the world from a different perspective: the one that everything is going through change and that most of us are unware of that. Why is the world changing? In this post I’ll point out the 8 reasons that lead me to believe it. 1- No one can stand the employment model any longer We are reaching our limits. People working with big corporations can’t stand their jobs. The lack of purpose knocks on your door as if it came from inside you like a yell of despair. People want out. They want to drop everything. Take a look on how many people are willing to risk entrepreneurship, people leaving on sabbaticals, people with work-related depression, people in burnout. 2- The entrepreneurship model is also changing Over the past few years, with the explosion of startups, thousands of entrepreneurs turned their garages in offices to bring their billion dollar ideas to life. The vortex of entrepreneurship was to find an investor and get funded. To be funded was like winning the World Cup, or the Super Bowl. But what happens after you get funded? You get back to being an employee. You may have brought in people not sharing your dream, not in agreement with your purpose and soon it’s all about the money. The financial end becomes the main driver of your business. People are suffering with it. Excellent startups began to tumble because the money seeking model is endless. A new way to endeavor is needed. Good people are doing it already. 3- The rise of collaboration Many people have figured out that it doesn’t make any sense to go on by yourself. Many people have awakened from the “each man for himself” mad mentality. Stop, take a step back and think. Isn’t it absurd that we, 7 billion of us living in the same planet, have grown further apart from each other? What sense does it make to turn your back on the thousands, maybe millions, of people living around you in the same city? Every time it crosses my mind, I feel blue. Fortunately, things are changing. Sharing, collaborative economy concepts are being implemented, and it points towards a new direction. The direction of collaborating, of sharing, of helping, of togetherness. This is beautiful to watch. It touches me. 4- We are finally figuring out what the internet is The internet is an incredibly spectacular thing and only now, after so many years, we are understanding its power. With the internet the world is opened, the barriers fall, the separation ends, the togetherness starts, the collaboration explodes, the helping emerges. Some nations saw true revolutions that used the internet as the primary catalyst, such as the Arab Spring. Here in Brazil we are just starting to make a better use out of this amazing tool. Internet is taking down mass control. The big media groups controlling news by how it suits best what they want the message to be and what they want us to read are no longer the sole owners of information. You go after what you want. You bond to whomever you want. You explore whatever you may want to. With the advent of the internet, the small is no longer speechless, there is a voice. The anonymous become acknowledged. The world comes together. And then the system may fall. 5- The fall of exaggerated consumerism For too long, we’ve been manipulated to consume as much as we possibly can. To buy every new product launched, the newest car, the latest iPhone, the top brands, lots of clothes, shoes, lots and lots and lots of pretty much anything we could our hands on. Going against the crowd, many people have understood that this of way off. Lowsumerism, slow life and slow food are a few excerpts of actions being taken as we speak, pointing out by contradiction how absurdly we have come to organize ourselves. Fewer people are using cars, fewer people are overspending, and more people are swapping clothes, buying used goods, sharing assets, cars, apartments, offices. We don’t need all of that they told us we needed. And this consciousness of new consumerism can take down any company living of the exaggerated end of it. 6- Healthy and organic eating We were so crazy we even accepted eating anything! It only needed to taste good, and everything would be alright. We were so disconnected that companies started to poison our food and we didn’t say anything! But then some people started waking up, enabling and strengthening healthy and organic eating. This is only to get stronger. But what has this got to do with economy and work? Just about everything, I’d say. Food production is one of the basic fundamentals of our society. If we change our mindset, our eating habit and our way of consuming, corporations will have to respond and adapt to a new market. The small farmer is getting back to being relevant to the whole chain of production. Even people are growing plants and seeds inside their homes as well. And that reshapes the whole economy. 7 — The awakening of spirituality How many friends do you have who practice yoga? What about meditation? Now think back, 10 years ago, how many people did you know by then who practiced these activities? Spirituality, for too long, was for esoteric folks, those weird-like and mystic people. But fortunately, this is also changing. We’ve come to the edge of reason and rationality. We were able to realize that, with only our conscious mind, we can’t figure out everything that goes by here. There is something else going on and I’m sure you want to get hold of that as well. You want to understand how these things work. How life operates, what happens after death, what is this energy thing people talk about so much, what is quantum physics, how thoughts can be materialized and create our sense of reality, what is coincidence and synchronicity, why meditation works, how it’s possible to cure using nothing but bare hands, how those alternative therapies not approved by regular medicine can actually work. Companies are providing meditation to their employees. Even schools are teaching the young how to meditate. Think about it. 8 — Unschooling trends Who created this teaching model? Who chose the classes you have to take? Who chose the lessons we learn in history classes? Why didn’t they teach us the truth about other ancient civilizations? Why should kids follow a certain set of rules? Why should they watch everything in silence? Why should they wear a uniform? What about taking a test to prove that you actually learned? We developed a model that perpetuates and replicates followers of the system. That breed people into ordinary human beings. Fortunately, a lot of people are working to rethink that though concepts such as unschooling, hackschooling, homeschooling. Maybe you’ve never thought of that and even may be in shock. But it’s happening. Silently, people are being woken up and are realizing how crazy it is to live in this society. Look at all these new actions and try to think everything is normal we were taught so far is normal. I don’t think it is. There is something extraordinary happening. Gustavo Tanaka, Waking Times Help Waking Times to raise the vibration by sharing this article with friends and family… Labels: AWAKENING, CONSCIOUSNESS, CREATIVITY, ILLUSION AND REALITY, LOVE, ONE WORLD, PSYCHOLOGICAL REVOLUTION, SELF KNOWLEDGE, TRUTH If the United States is Nazified, Eurozone is the New Soviet Union When World War 2 ended everybody celebrated the fall of the Nazis only to find later on that their very country is occupied and ruled by Nazi agents. This is now the case with the European Union that behaves more like the collapsed Soviet Union. “The Soviet Union was governed by 15 unelected people, who appointed each other and who were not accountable to anyone. The European Union is governed by two dozen people, who appoint each other and are not accountable to anyone.” “I have lived in your future, and it didn’t work.” Vladimir Bukovsky, Writer, lecturer and political dissident from the former USSR The European Union was sold as a common market that is turning out to be a common dictatorial regime for the Oligarchy where all member countries, hence its people, are all powerless when it comes to protecting their sovereign interests. The common government serves only the common agenda of the Oligarchy in a more streamlined fashion, in keeping with the reengineering doctrines of the era. Those people who were behind the creation of the USSR are themselves members of the elite Knights of Malta, a millitary organization sworn to defend and protect the Papacy. “1917—The Russian Revolution takes place. The Bolsheviks (Communists) seize power in Russia—funded by wealthy Knights of Malta in the United States. Later, two Jesuit-trained thugs, Joseph Stalin and Catholic Cardinal Agagianian, oversee the Soviet Gulag system. (Note: Both Stalin and Agagianian had been trained at the Jesuit Seminary in Tiflis, Soviet Georgia.) Millions of Russian Orthodox Christians are butchered at the hands of a totalitarian Police State. (Remember, the Vatican has long hated Orthodox Christians, and has slaughtered them whenever and wherever it could.” http://revoltnow.wikifoundry.com/page/Jesuit-Trained+Movers+and+Shakers A project forced through by stealth @SamGerrans The EU is a lesson in deceit. Like joining a cult or a pyramid scheme, the true nature and cost of the abusive system one is entering are hidden until after the ink has dried on the contract; and having joined, one will not be privy to the agenda guiding what one is now paying to support. The New York Times puts the underhand nature of the incremental creation of a European bloc into perspective, almost in passing. Looking at Cameron’s recent Brussels visit, the paper notes: “The departure of Britain from the bloc would throw into reverse for the first time the so-called European project, a program of integration that began with six countries with the establishment of the European Coal and Steel Community in 1951 and that has since expanded to 28 nations, with several others eager to join.” That’s right, this entity which tells the Prime Minister of Britain what he can and cannot do began life as a coal and steel agreement. In hindsight, it is clear that this 1951 treaty was simply a purchase point needed leverage in what was to follow. The agreement itself expired and was abandoned in 2002 and one is left wondering at what undeclared future milestones existing agreements are, in fact, directed. The man who in 1973 took the UK into what was then called the European Economic Community or Common Market was Conservative Prime Minister Ted Heath. In October 2011, Conservative Member of Parliament, Mark Reckless, said during a debate on an EU referendum that Ted Heath had promised the British public that “they would have the veto over any important issues.” He continued: “Yet those same people are now told that what they were then told was a common market, has become a political union in which we can be outvoted whether we like it or not.” This, then, was a clear case of bait-and-switch. Heath controlled by outside forces? Since his death in 2005, Heath has been implicated in child molestation cases. The Guardian reports: “An alleged victim, a woman, was interviewed by Clive Driscoll[…] He retired last year having reached the rank of detective chief inspector. Driscoll told the Guardian the woman he interviewed said she had been abused as a child by a group of people, including Heath on multiple occasions: “The person was 100% sure they were talking about Ted Heath. She totally believed what she was saying and that’s where the investigation starts, not where it stops.” The woman claimed the abuse happened at a time after Heath had served as prime minister. Driscoll said others made similar abuse allegations, but he was not asked to take statements from them.” Whether the Establishment will close ranks on this case as it has on that pertaining to EU Commissioner Leon Brittan remains to be seen. If the allegations against Heath are true, it is unlikely that such an abhorrent feature of his sexual character surfaced only when he was out of office. And that being the case, he would have been entirely controlled by whatever person or agency had the dirt on him while he was Prime Minister. My point is this: the history of the development of the EU project bears witness to a clear and pre-existing agenda – one which has remained hidden from the view of both the public and non-senior Members of Parliament. And as regards the UK, susceptibility to blackmail by outside forces in the case of the primary actor in the legislative process which resulted in membership must be considered a genuine possibility. ​Jimmy Savile: ‘It couldn’t happen again.’ Yes it could and it’s probably happening right now Pre-existing agenda In the light of the above, the underlying policy behind the EU project increasingly looks like a pre-agreed business plan whose KPIs relate solely to implementing that plan while masking the fact of its existence and ensuring compliance – at any price. In such a case, the rules of realpolitik require that the implementation of policy be seen as responses to external circumstances or to the will of the population. Thus, mass non-European immigration and the transformation of discrete, largely homogenous white countries into a culturally lost, self-loathing wasteland look less like a blunder of some kind and more like an expression of original intent. George Soros, a Hungarian Jew who got his first business breaks collaborating with the Nazis – the source for which information is his own father’s book Masquerade—Dancing Around Death in Nazi-Occupied Hungary – has a plan ready for the next stage for Europe. This plan begins with accepting 1 million refugees. Sputnik News regards the current influx as “a social engineering project” and event engineered – at least in part – by Soros himself. But there is no reason why the EU – or the US for that matter – should be inherently spastic when it comes to the business of protecting their own boarders; not unless the fix is in from above. Israel, for example, does not see armies of migrants converging on its territory. That is because Israel is not in the business of tolerating the type of suicidal policies Soros so ardently wishes upon Europe. Israel intends to survive. And it does so by enforcing its borders and its racial policy and repelling those who do not fit with that remit. So which is it? Can modern states protect their borders or not? I don’t mind, so long as we are consistent. Is it so unreasonable for the US and the EU to aspire to the type of border controls Israel enjoys? For the record, while I can get behind a true constitutional republic such as America once had, I have no time for democracy which I regard as a mechanism designed to simulate choice while facilitating compliance. So I am not here to wax lyrical about democracy on my own account. What interests me more is the cognitive dissonance those who do believe they have a choice must experience when they see that on any subject which matters the man they are told represents them – in this case Cameron – is flicked away by EU grandees like so much fluff when he wishes to be seen to try to take an actual decision when the very history of the EU itself implies the pursuit of a covert, non-democratic agenda. Perhaps an answer is to be found in the words of Aldous Huxley in Brave New World: “A really efficient totalitarian state would be one in which the all-powerful executive of political bosses and their army of managers control a population of slaves who do not have to be coerced, because they love their servitude.” Warning from the future Writer, lecturer and political dissident from the former USSR, Vladimir Bukovsky, delivers a blistering comparison of the European Union with the Soviet Union. His catalogue of comparisons includes the fact that: “The Soviet Union was governed by 15 unelected people, who appointed each other and who were not accountable to anyone. The European Union is governed by two dozen people, who appoint each other and are not accountable to anyone.” His disturbing and lucid monologue concludes with the words: “I have lived in your future, and it didn’t work.” https://www.rt.com/op-edge/326577-eu-ussr-brussels-london/ The disconnect in public awareness is rooted on the fact that the mainstream media won’t go higher beyond the political facade. But that is only normal since the powerful bloodlines behind that facade own the largest media networks on the planet. It is therefore our task to help spread the neglected portion of the Truth to as wide and as far as possible. Posted by SATHYA at Monday, December 21, 2015 No comments: Labels: AMERICA, AWAKENING, BANKING SYSTEM, CIA, CONSCIOUSNESS, CONSPIRACIES, CORPORATE CORRUPTION, FASCISM, FEDERAL RESERVE, GLOBAL POLITICS, ISRAEL, KHAZARIAN MAFIA, NATO, PROXY WAR, TERRORISM, WAR IS A RACKET, ZIONISM
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Cookies provide several advantages to improve interactive services and make web browsing easier. By continuing to use this website you agree to our use of cookies. More Information Confirm To be able to use Salewa® International in full range, we recommend activating Javascript in your browser. Join us and receive a Voucher See Details Birth Day 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 Birth Year 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 1985 1984 1983 1982 1981 1980 1979 1978 1977 1976 1975 1974 1973 1972 1971 1970 1969 1968 1967 1966 1965 1964 1963 1962 1961 1960 1959 1958 1957 1956 1955 1954 1953 1952 1951 1950 1949 1948 1947 1946 1945 1944 1943 1942 1941 1940 1939 1938 1937 1936 1935 1934 1933 1932 1931 1930 1929 1928 1927 1926 1925 1924 1923 1922 1921 1920 1919 1918 1917 1916 1915 1914 1913 1912 1911 1910 1909 1908 1907 1906 1905 1904 1903 1902 1901 1900 1899 I consent to the processing of my personal data for the sending of Salewa newsletters Log in to accept the Privacy Policy New customer? Create an account? Salewa International English Salewa Germany German Salewa Austria German Salewa Switzerland German Italian French Salewa Italy Italian German Salewa France French Salewa UK English Salewa Spain Spanish Salewa USA English Insulation & Down Jackets Hardshell Trousers Longsleeves Baselayers Mountaineering Shoes SpeedHiking Shoes Headbands & Necktubes Facemasks & Balaclavas FOLLOW THE RACE DISCOVER THE ALPENVIOLET FREE SHIPPING FROM 200€ (malta 300€) Insulation & Down Jacket Shorts & Skirt Speed Hiking Shoes FREE SHIPPING from € 200 (Malta € 300) T-shirts & technical shirt Bottom & Shorts SPECIAL PRICE COLLECTION Mountaineering Backpacks Hiking & Trekking Backpacks Speedhiking Backpacks Climbing Backpacks Daypack & Travel Backpacks Backpacks Accessories Sleepingbags & Pads Sleepingbags Extreme Low Temperatures Sleepingbags Moderate Temperature Liners & Bivy Bags Mats & Accessories High Mountains Tents Alpine Trekking Tents Tents Accessories Belay & Security Devices Carabiners & Sets Iceaxes & Icescrews Our Headquarter Social & Environmental Responsibility Salewa's best in your Inbox FREE SHIPPING FROM € 200 ( Malta € 300 ) Your Choice: Release date Maximum price Popularity Minimum price Product Name Raven 2 GORE-TEX® Men's Shoes 30% + 20% MS MULTI TRACK Lite Train Men's Shoes Firetail 3 GORE-TEX® Men's Shoes Mountain Trainer Mid GORE-TEX® Men's Shoes MS ULTRA TRAIN GTX MS MULTI TRACK GTX UN WILDFIRE PRO Speed Ascent Men's Shoes MS FIRETAIL 3 Hike Trainer Mid GORE-TEX® Men's Shoes UN VULTUR GTX Wander Hiker Leather Men's Shoes EQUIPMENT End of season Sales Cookies Imprint Privacy Policy Redirect Sitemap Sitemap Terms & Conditions Secure Shipping the salewa guarantee
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FNLC plans water quality improvements for Deer Brook Gully Posted by Mike Frett | Jun 21, 2019 | News, Showcase News | 0 | Stone Environmental's Amy Macrellis speaks with FNLC's Kent Henderson, Secretary of Natural Resources Julie Moore and Secretary of Transportation Joe Flynn during a visit to the gully last November. (MICHAEL FRETT, Messenger Staff) GEORGIA – A collaborative study between the Friends of Northern Lake Champlain (FNLC) and Stone Environmental has identified a handful of projects in Georgia’s South Village for mitigating runoff into a gully funneling directly into the Lamoille River watershed. Projects recommended by the study are trained on both stymieing the amount of phosphorous-carrying sediment entering the gully in question as well as slowing that water as it enters the gully, hopefully reducing the threat of erosion. The “Deer Brook Gully,” as the South Village gully is called, was carved into the watershed by stormwater improvements built in southern Georgia following the construction of Interstate 89 and subsequent developments. That gully, in turn, drains into Deer Brook, which later empties into Arrowhead Lake and the Lamoille River before ultimately ending in Lake Champlain. According to Stone Environmental’s report on the gully, that stormwater infrastructure is undersized compared to the amount of water it now handles, leading to excessive water pressure building within that system that jets water into the gully. “The problem is that the piping system is all 12-inch to 18 inches of pipe, which is pretty undersized considering the size of the watershed,” said Stone Environmental’s Gabe Brolin during a presentation to the Georgia Conservation Commission. “The swales will hold a lot of water and kind of create a hydraulic pressure pushing the water down into the piping network,” he said. “But that ‘hose’ is only so big in diameter, so the water starts rushing through.” Compounding the velocity of that runoff was the height of the drainage pipe relative to the gully. With the drainage pipe set between 20 and 30 feet above the gully, water shot into the gully has an additional acceleration from its fall. Deer Brook is cited by the Vermont Department of Environmental Conservation (DEC) as an “impaired waterway” due to erosion caused by stormwater that washes through the watershed. DEC lists “sediment” as the primary concern for the Deer Brook watershed, which, according to the Environmental Protection Agency (EPA), can cloudy a waterway, impact abutting habitats and carry nutrients like phosphorus downstream. Per Stone Environmental’s report, about 70 percent of the banks tracing the gully toward Deer Brook are “actively eroding.” The Messenger previously visited the gully, observing fallen trees strewn over the then-trickle of water as it led toward Deer Brook. The banks, meanwhile, were lined with trash, ranging from bikes and drum barrels to scraps from discarded vehicles. Stone Environmental’s report makes similar observations in the gully, noting that approximately half of the downed trees “appeared to be recent falls… with not signs of rot or weathering.” The report describes a particular visit to the gully in the immediate aftermath of a rainfall, where, according to Brolin, water had mixed with silt lining the bottom of the gully, producing a gray sludge that drained through the gully. “At the confluence of Deer Brook, a contrast between the gray colored gully discharge and brown flow in the brook was easily discernible,” the report reads. Stone Environmental’s study prioritized nine improvements for stormwater infrastructure in the South Village in order to reduce the amount of runoff jetting into the gully, with a projected cost of around $400,000 that FNLC hopes to cover with grant appeals to the Clean Water Fund. The study also provides numbers gauging the impact of those improvements, such as the amount of phosphorus it could remove from a watershed, and ranks those projects according to how easy their construction would be. The Messenger previously visited the gully, observing fallen trees strewn over a then-trickle of water as it led toward Deer Brook. (MICHAEL FRETT, Messenger Staff) Those numbers, according to FNLC president and Georgia Conservation Commissioner Kent Henderson, should help FNLC’s grant applications once it starts pursuing those projects. “Is really going to play nicely with the new Clean Water Act,” Henderson said. “[The state] wants a number for the amount of phosphorous you’re keeping out with an amount of money… and we have it.” Of those nine recommended projects, seven were designed to slow and filter water entering the system and exist within the state’s right of way for Route 7: Four are gravel wetlands to be built near Georgia Auto Parts, Interstate Auto Services, Georgia Market and Whites Bikes & Outfitters; Two are catch basin risers that would raise the elevation of the catch basin’s grate to allow for slower drainage from two of the swales tracing Route 7; and A catch basin that would incorporate a deeper sump – a pit for collecting water – to allow for sediment in the system to settle before the water moves on. The two catch basins described by Stone Environmental would still sit below road level, allowing the water to drain into Route 7’s drainage system rather than spill out of the swale and flood the highway. Two improvements meant to slow water entering the gully would be built on private property. One would see a staggered manhole system that would lower the exit pipe into the gully and dissipate some of the water’s velocity as it transfers between a pair of manholes before entering the gully. The second improvement would be a series of log wood steps built into the gully’s channel, creating barriers to slow water and allow for sediment to build up at those steps rather than drain directly into Deer Brook. These projects are within Georgia’s South Village, an area viewed by town officials as Georgia’s development center. Development in the area has led to an increase in impervious surfaces throughout the South Village, leading to more water running into the area’s stormwater system. According to the study, approximately half of the gully’s watershed is considered an impervious surface, a ratio that Georgia Conservation Commission chair and planning commission chair Suzanne Brown said would only become more challenging as projected development continues in the village. “It’s the village,” Brown said. “It’s only going to get worse.” Henderson said FNLC would start applying for grants to fund improvements in the watershed this fall, when the next grant cycle begins. FNLC, a water quality advocacy group active in Franklin, Grand Isle and parts of Chittenden County, initially contracted with Stone Environmental in 2017 to study the gully’s watershed. The study was supported by a DEC grant awarded in 2016. Stay informed. Subscribe to the Messenger. Reducing runoff in Georgia: Proposal targets stormwater in South Village PreviousJudge upholds Act 46 NextPeter “Pop” Malchiodi Mike Frett
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Amori che non sanno stare al mondo Stories of Love that Cannot Belong to this World Claudia and Flavio were passionately in love for a long time. Then their story ended and things were not easy, especially for her. After a few years, their world is adrift. Flavio feels the need to keep on going, down on the ground; Claudia would rather never forget. A sentimental comedy about a love story that is not fit to survive, with a touch of irony and a new beginning. Museum of Photographic Arts 1649 El Prado Balboa Park Explore San Diego Neighborhoods Downtown & Gaslamp Quarter Baja Regions Nighttime Zoo at the San Diego Zoo Jun 16 - Sep 2, 2019 Stay after dark and celebrate summer during Nighttime Zoo presented by One Medical, June 16 through September 2. Enjoy live music, fun shows, animal encounters, food, and more! Del Mar Racing Season Jul 17 - Sep 2, 2019 San Diego horse racing takes place where the "turf meets the surf" at the Del Mar Racetrack. Fans flock to the track each summer to wager on their favorite horses during the popular, annual Del Mar Thoroughbred Club racing season, mid-July - early-September. Be part of the magic and nostalgia of this long-time horse race tradition dating back to 1937 when Bing Crosby greeted the first guests, and Seabiscuit won by a nose in the infamous race in 1938. This season features the nation's top race horses, trainers and jockeys, and plenty of fun in the sun. The races run five days weekly, except Monday and Tuesday. Horse racing at Del Mar happens Wednesday through Sunday, with post time for the first race on most days at 2:00 PM. On Fridays first post is 4:00 PM. LIVE MUSIC: GRAHAM GILLOT BAND “Graham Gillot Band” is a highly enjoyable Contemporary Musical Extravaganza performed by some of South Africa's top musicians. By combining catchy original vocal songs with virtuosic instrumental music, this act is defining its own sound. To make a restaurant reservation, please visit http://www.houseofblues.com/sandiego/restaurant. Schedule is subject to change. Please check House of Blues San Diego website for the most up to date schedule. Visit www.houseofblues.com/sandiego. Atomic Groove - Opening Day Party! Atomic Groove is San Diego’s BEST in variety dance band entertainment, serving the special event industry for parties, galas, fundraisers, weddings and more since 1995. Like what you see? Share with your friends, family, and the world!
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Salmon Arm Silverbacks 101 things to do in the Shuswap Vacation Shuswap COLUMN: The year we almost lost Canada Day Members of the Summerland Legion have ensured our national holiday is celebrated here John Arendt Jul. 5, 2019 12:30 p.m. It was a celebration of Canada as hundreds of people attended the Canada Day events in Summerland’s Memorial Park on Monday. The event featured speeches by dignitaries, a flag-raising, activities for children, a barbecue and a cake in honour of Canada’s 152nd birthday. It wasn’t the biggest Canada Day celebration in the country, but it was ours. Summerland’s Canada Day event is something for this community to treasure, in part because the day almost went unobserved here a few years ago. That was in 2010. As July 1 was approaching, no group or organization had planned any festivities for the day. The Legion stepped forward and as a result, Canada Day celebrations continued. “This Legion is not going to let this town down,” said John Lawrie, president of the Summerland Legion at the time. “If nobody else picks up the ball, we will.” And in the years following, the Legion has organized Canada Day festivities each year. READ ALSO: Summerland Legion organized Canada Day celebrations READ ALSO: QUIZ: How much do you really know about Canada? “This Legion will not allow Canada Day to go uncelebrated,” Lawrie said about the Legion’s involvement. “Too many people lost their lives to give us independence and freedom. We will not forget them.” The Summerland Legion volunteers deserve praise for this annual effort in giving us a local event to celebrate our national identity. Still, it’s hard to believe Summerland could get to the point where the future of Canada Day celebrations was in jeopardy. In the 1990s and early 2000s, Summerland billed itself as “Towne of Festivals.” It was a time when there were plenty of festivals, events and special activities from spring until early fall each year. There was the Children’s Festival on the Saturday of the Easter weekend, the Summerland Action Festival, Canada Day on July 1, Family Fun Day on the August long weekend, A Taste of Summerland on the Labour Day weekend and the Summerland Fall Fair in early September. Other community events have included car shows, a rodeo, a motorcycle gathering and a music festival. We’ve lost some of these events. It has been many years since Summerland held Family Fun Day and A Taste of Summerland. The Children’s Festival faded away more than a decade ago, although in recent years Remax Orchard Country in Summerland has done a stellar job in making this event happen once again. READ ALSO: Children gather for Easter festival in Summerland Even the Summerland Fall Fair, a community tradition for more than a century came to a close several years ago. Last year, a team of dedicated and enthusiastic volunteers brought back this event. And Summerland now has a recent addition to its festivals as the Ryga Festival is held during the Labour Day weekend. Anyone who has worked with a festival knows a good event takes a lot of work. The committee involved in the Summerland Action Festival works year-round in order to organize an event that lasts for one weekend in early June. READ ALSO: Summerland celebrates 37th annual Action Festival READ ALSO: Summerland holds two-day Fall Fair The same is true of other festivals and special events. The effort is significant. It takes plenty of time and energy to set the date, book the venue, arrange the entertainment and schedule of events, book the performers and attractions, organize the vendors, set up and take down stages and seating and make sure the garbage is cleaned up at the end. All those tasks and more are needed in order to ensure everything runs smoothly during the event. Without the dedication of a good team of volunteers, it becomes difficult if not impossible to organize a special event. The members of the Summerland Legion have stepped up and as a result, Canada Day celebrations are able to continue in Summerland. John Arendt is the editor of the Summerland Review. news@summerlandreview.com. news@summerlandreview.com When God moved the mountain: The Hedley slide of 1939 Letter: Willingness to show anti-abortion film “despicable” Letter: Better ways for Downtown Salmon Arm businesses to address poverty Prohibiting sitting or lying down both measures designed to make poverty invisible and criminal Salmon Arm actor, writer takes stab at thriller for silver screen Now living in New York City, Dani Baker wrote and is starring in Follow Her. Column: Fraser River fish ladders and the mystifying determination of salmon Shuswap Outdoors by Hank Shelley Explore Salmon Arm Observer Salmon Arm Weather Salmon Arm Classifieds © 2019, Salmon Arm Observer and Black Press Group Ltd.
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96. ANTONIE van LEEUWENHOEK (October 24, 1632 – August 26, 1723) Like Michael Faraday, Antonie van Leeuwenhoek had very little education. He was an artisan whose lens-making business transformed into a research scientist. He made and sold a variety of lenses, whose primary uses were as telescopes and reading-magnifiers. Having crafted these glasses for a long while, he decided to engage in amateur investigations. His observations of bacteria (which he called animacules) made him the first person known to have seen these microorganisms. As a result, it had him being tagged the “first microbiologist” and the “father of microbiology”. Van Leeuwenhoek’s microscopes were rudimentary: with estimated magnifying powers of between 200x and 300x. Notwithstanding they were powerful enough to grant him visual access into a hitherto unknown microbial world. Other cells he studied ranged from simple unicellular spermatozoa to complex multicellular muscles, fungi, insects and arthropods. He meticulously documented his findings: many of which he later shared (as letters) with the London Royal Society. Being an artisan with little education meant that he could only write in his native Dutch. But the significance of his works was such that the Royal Society had them translated into Latin and English, before publishing them. Those publications brought him so much fame that dignitaries such as: Gottfried von Leibniz, Prince William III of Orange and his wife Queen Mary II of England, Scotland and Ireland visited him. He was also granted audience with Czar Peter the Great of Russia in his royal yacht. Dedicated in his honor is the lunar crater: Leeuwenhoek. PreviousPrevious post:95. SERGEI PAVLOVICH KOROLEVNextNext post:97. JESSE ERNEST WILKINS, Jr. Wendy Quinonez says: I ⅼike the info you provided and will be visiting again soon. Best of luck! Dan Furneaux says: Great website with wonderful contents! I see why you rank high in google. Tony Bridgestone says: Wow! From a common trader to a great scientist. Intellectual elevation must have been easier in his days. Bruce Williams says: Wow! I have spent hours here without realizing it. Goes to show how interesting the site is. Emelda Hamilton says: Great to see fine pieces of writings throughout this website.
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Military Schools for Girls in Louisiana -- LGA is a military-type school for girls in Louisiana and across America – Christian boarding schools and affordable schools. Military Schools for Girls in Louisiana Home » Military Schools for Girls in Louisiana Researching Military Schools for Girls in Louisiana? As you are looking for military schools for girls in Louisiana you need to know that there are not many such female military schools, so you might want to also consider Lakeland Girls Academy. It is a school for at-risk teenage girls, situated in Lakeland, Florida, just a few miles from Orlando. Compared to military schools for girls in Louisiana, LGA is a program that teaches military-like discipline and respect. If the format of a military school for girls specifically interests you, some therapeutic boarding schools adhere to a military style and teach discipline. Even in those that do not have a military emphasis, most therapeutic schools use structured daily schedules to teach order, and quite a few involve students in daily chores to show responsibility and work ethic. Lakeland Girls Academy is not a military school, but it is similar. For girls ages 12 to 17, LGA provides life counseling and invites parents to periodic Family Weekend sessions meant to rebuild family relationships. It is a disciplined, safe haven for girls to grow and mature. With no boys on campus, it takes away one significant source of distractions. While LGA focuses attention on character building, emotional growth and relationship healing, it also provides a quality education. Much emphasis at LGA is placed on character building and values. Education also takes a priority position, because LGA recognize that academic performance commonly slips when other difficulties creep into life. It offers a fully accredited school. Teens at Lakeland Girls participate in plenty of activities, with each one designed for growth. A daily schedule and assigned tasks develop discipline and responsibility, while intramural sports and outdoor activities keep teens active and build positive character traits. Girls become well-rounded individuals as they try activities from dance to cooking to community service and cultural events. More Information About Military Schools for Girls Even though military schools have historically been available only to boys, a few military schools for girls have opened their doors in recent years, but nearly all of them are coed. Both boys and girls enjoy the advantages of the top educational opportunities, leadership training, moral development and self-confidence gained at a military environment. Increasing numbers of girls desire a career in the armed forces. A military school for girls can serve as excellent preparation for top military positions or as a college prep program for pursuing a profession in another field. What Do Girls Gain from Military Schools for Girls? Military schools for girls expect excellence, and students rise to the occasion to build habits of excellence in their lives. The precise order and personal responsibility associated with military discipline can complement an academically challenging curriculum. Challenging physical training calls for mental and physical self-control and produces disciplined, strong young ladies. While they discover how to properly look after their health and become physically conditioned, young ladies in a military school for girls develop a more alert state of mind that permits them to accomplish a great deal. Military discipline could also be used for behavior modification to transform rebellious behavior into respectful behavior. Just like military schools for girls in Louisiana, LGA has earned a high reputation for instilling confidence and character in the lives of troubled girls. It concentrates on healing and restoration to give troubled teen girls the freedom to build the same kind of integrity and personal strength. More about military schools for girls in Louisiana: Louisiana (LA) is a state located in the southern region of the United States of America. Louisiana is the 31st most extensive and the 25th most populous of the 50 United States. Its capital is Baton Rouge and largest city is New Orleans. Louisiana is the only state in the U.S. with political subdivisions termed parishes, which are local governments equivalent to counties. The largest parish by population is East Baton Rouge Parish, and the largest by land area is Cameron Parish. Some Louisiana urban environments have a multicultural, multilingual heritage, being so strongly influenced by an admixture of 18th century French, Spanish, Native American (Indian) and African cultures. The ten largest cities in Louisiana are: New Orleans, 369,250; Baton Rouge, 230,058; Shreveport, 201,867; Metairie, 138,481; Lafayette, 122,761; Lake Charles, 73,474; Kenner, 66,820; Bossier City, 64,655; Monroe, 49,156; Alexandria, 48,367. Excerpt about military schools for girls in Louisiana, used with permission from Wikipedia. Lakeland Girls Academy is similar to military schools for girls in Louisiana. It is located in Lakeland, Florida but enrolls troubled girls from across America and internationally. We can also help you in your search for affordable boarding schools, teen boarding schools, traditional schools or Christian boarding schools. Our Christian therapeutic program helps misbehaving girls who are at risk and having behavioral issues such as anxiety, who are oppositional, with reactive attachment disorders, and avoidant personality disorder. Military schools for girls are probably not the best option for your troubled teen girl. Many military schools for girls won’t enroll girls who have a history of problems. When dealing with troubled teens, there are many types of residential schools which can help troubled girls. Not all Christian boarding schools work with struggling teenagers. Programs which specifically help teenagers in trouble are typically referred to as therapeutic boarding schools or reform schools. For troubled teenagers in need of spiritual guidance, Christian boarding schools are a great answer. Christian boarding schools provide Bible-centered treatment for at-risk teens, as opposed to other alternative schools and therapeutic boarding schools schools without a Christian emphasis. Military Schools for Girls in Louisiana -- LGA is a military-type school for girls in Louisiana and across America
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Translations: en, tr, ru All Media Baltics to Deliver Top-quality TV Reception via SES Video Luxembourg, 19 December 2017 – All Media Baltics’ Pay TV subscribers will be able to enjoy the broadcaster’s channel package in HD quality, including its original premium TV channels, at 5 degrees East, following a multi-year capacity agreement announced by SES. Under the agreement, All Media Baltics will use several transponders of satellite capacity on ASTRA 4A to distribute its five original channels and its pay TV channel package to the Baltics, which includes movies, entertainment, and sports. All Media Baltics was created in October 2017 after Providence Equity Partners acquired all of the media and Pay TV companies of Modern Times Group in the Baltics, which was already relying on SES for delivery of its TV package at 5 degrees East. With this agreement, All Media Baltics ensures continuity for audiences and leverages the wide reach of SES’s prime orbital position over the Nordic and Baltic region: SES reaches 1.73 million TV homes in the Baltics at that slot, representing 65% of all TV homes in the market. “Not only do we provide premium DTH services, but we are also in the best position to bring high definition content to TV households in the Baltics, as we serve 78% of HDTV homes in the region via our satellites,” said Håkan Sjödin, Vice President, Sales Nordic, Baltic and Eastern Europe at SES Video. “We are very pleased to support All Media Baltics with its DTH needs in high definition and we look forward to helping them continue to grow.” “TV entertainment requires high quality content and also reliable broadcasting services in order to satisfy our viewers,” said Arvils Kupris, COO All Media Baltics. “SES has a track record of providing top-quality broadcasting services. We are confident that the company will help us continue entertaining our audience in the best possible way and to ensure premium quality services.” About All Media Baltics On 18th October 2017 Providence Equity Partners (PEP) has acquired MTG Free-TV, Pay -TV, digital and radio businesses in Baltic region. Company continues to operate as All Media Baltics. AM Baltics brands are: TV channels TV3, LNT, TV6, Kanāls 2, 3+, TV8, radio channels Star FM, Radio Volna and Power Hit Radio, largest AVOD video portals TVplay and TV3play, news and entertainment portals Skaties.lv, Uudised.ee and TV3.lt, as well largest video content platform in the Baltics Viaplay, satellite Pay TV provider Viasat and SmartAD.
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tv NBC Bay Area News at 6 NBC November 25, 2016 6:00pm-7:01pm PST the letter? >> reporter: there is some concern in the mosque tonight. because there are direct threats. the local imam opened the letter yesterday. this is the letter. the opening lines themselves were alarming to community people who red the ledder. quote to the children of satan, you muslims are a vile and filthy people." >> shocked and then we realize there's a handful of people like that who would react to the political climate. >> reporter: the local imam opened the letter yesterday. "there's a new sheriff in town, president donald trump. he's going to cleanse america." >> it's absolutely threatening. >> reporter: supervisor david cortez received the letter from the mosque. >> when someone starts off a letterer addressed to the children of satan and end it by saying the same thing's going to happen to them as in nazi germany, i think that's more than a veiled threat. >> reporter: they're investigati investigating. the mosque says officers were at the center within minutes. >> given they reacted in the way they did with compassion and care, it blows us away. it reinforces the belief in the community. >> reporter: the mosque will not be deterred by the letter, vowing to continue their work in the community. i did check the address on that return envelope. that address does not exist. i also speak with the diocese of san jose. the bishop will reach out to the mosque in a show of solidarity. nbc bay area news. and turning now to our microclimate forecast outside here for a live look at san jose where it's pretty clear, chill ea as well. meteorologist standing by with a storm thats are headed our way. >> yeah the evening' dry around the bay area. temperatures in the low to mid-50s right now and partly cloudy skies in san francisco. you can see all the way out the golden gate bridge but rain is lurking. right now not on our local radar sweep. you see the rain approaching and this is the first of three systems in three days bringing a chance of wind and rain. that is how the weekend begins. winds 15 to 30 miles per hour. widespread rain for the morning and this weekend could be the biggest in terms of snowfall we've seen so far this fall. as you can see in the sierra maybe as much as two feet of snow but snow levels as low as 3500 feet which means places like mount hamilton could get a dusting of snow on saturday night. we'll let you know the timeline of three systems impacting us over the next three days. thanks so much. do stay ahead of the rain. get the nbc bay area app. the hunt for two escaped inmates has moved into santa clara. as we told you yesterday forty-four inmafour inmates escaped. two caught, two on the loose. nbc bay area's robert handa is there with the search team and tell us you learned new information. >> reporter: we're at the south end of the main jail where behind me is the jail window where the inmates made their escape. sources tell me the suspects actually went out the window about half an hour after the first two inmates. so the captured inmate may have simply saw an opportunity. and the search dogs apparently picked up their trail from that window and investigators say they're closing in. santa clara county sheriff's investigators say the search dogs were given items belonging to the n mates and started tracking. they followed the dogs all the way underneath the underpass of 880. they confirmed they believe that's how they left the area and based on tips the dogs pick up the trail in a neighborhood near levi stadium. >> one of them speaks of them being seen in that area and with the use of the dogsx that confirmed that. we arer getting closer. >> reporter: law enforcement agencies are looking for chavez recently booked in august. this is a photo of chavez. the man with the distinctive facial tattoo was serving charges for numerous charges. and the other inmate is luroan campbell including false imprisonment and criminal threats. >> we will find these two and any person who is harboring or helping or aiding and abetting in their escape will attempt to prosecute. >> reporter: now coming up at 6:30, we'll have anotherer update including the strange journey of one of the men who was caught. >> thank you. now these are the first reports of inmates escaping from inside the main jail but not the first time an inmate escaped from outside the jail. last year josh snell carter over powered a deputy before catching a bus to reno. he was later found in mississippi. as for the current search, we'll be working the story around the clock. go to our bay area app and facebook page. the mysterious disappearance of a california mother made national headlines and now her reappearance is even more stunning. she was found tied up on the side of the road thanksgiving morning. jodi hernandez is live in redding where the woman's sister held a news conference late this afternoon. and a lot of questions surrounding this case. >> reporter: a lot of questions. a family friend tells me that sherry is doing surprisingly well as she tries to put the pieces back together. late today her sisterer talked to reporters that church are sherry and her husband were married. she's just so thankful her sisterer's ho e sister's home. >> just been a range of emotions and sadness, anger. >> reporter: sheila coaster can describes what the last few weeks have been like for their family. but their prayers have been answered. three weeks after her 34-year-old sister disappeared while jogging, the mother of two was found tied up on the side of a yellow county road on thanksgiving morning. >> everyone's tireless efforts has made our family whole again this thanksgiving evening. >> this afterf campbell randal released video, first asking for a ransom if they returned unharmed. >> there are no cops involved. they have not been involved from the beginning. >> reporter: he says he didn't pay ransom or bounty but believes the aufrs put pressurer oren the abducters to let her go. her sister didn't want to talk about the investigation but says she's incredibly grateful to everyone who helped. >> we are overwhelmed with joy of how supportive everyone has been to help bring us together as a family again. >> reporter: shasta county sheriff's investigators say they are looking for two hispanic women armed with a handgun and driving a dark colored suv. they did not release any additional information. >> all right, thank you very much. we're constantly updating this story. also you can find all of it on our website, nbcbayarea.com. well, it has been three days and searchers still have not found a woman who went missing in mendocino county. she was last seen hunting for mushrooms. she had throat surgery recently and may have had difficulty calling for help. anyone with information is urged to contact investigators. and only on nbc bay area, football legend ronny lot tells us about his plans to keep the raiders in oakland. lot was in the studios tonight. he's rallied several locals to . and lot has received the support of oakland mayorer, libby shaft but he continues to stay committed to las vegas. >> because in life what you try to do is you put something on the table that you hope you can't refuse. that hasn't been the case. and until we are able to do that, then that should be the posture he should take. he's got something that is very valuable and that is a bid in las vegas. he doesn't have that here. and until he has that and i think john madden said it. yeah, they want to stay here, they want to be here but it takes all the parties to come together to make it happen and the tough part now is that time is running out. >> okay. we know football fans and raiders fans are watching every twist and turn. this is where it stands. city and county leaders will be meeting in a closed session on tuesday. if they approve lott's proposal, that will head to a discussion the following week. and we'll tell you which prominent sillicon valley businessman might be part of this investment group. and can you believe it? it's already here. holiday bargain shoppers are out in full force tonight. live in walnut creek. straight ahead a new twist on black friday. hit in thp head with a skateboard. the update on the officer attacked in south san forirancf. and plan on a chilly weekend ahead. temperatures in the mid-50s as we track rain, wind and thunder. all in the forecast. nine straight losses thp. the 9ers worst streak since 1978 and they'll be heavy underdogs against the dolphins team that has won five in a row. >> we still have the opportunity to win a game. that's what we have to stay focussed on and take it one week at a time. there is that feeling that we're not going to be in the playoffs and we'll have have an opportunity to build on things for next year. a skateboard attack on tape all caught on camera. the skateboarder trying to ride off. and here showing the foot chase coming to a violent end. cristie, there were witnesses who saw this attack? >> reporter: that's right and people on the street were just shocked by what they saw. they say this man was given many chances to cooperate with police but that he didn't. they say there was a short foot chase. suddenly the officer was hit and he was down. i wanted to show you a picture posted on the linkedin page of officer robby chon. they're speaking out against the violent attack. >> the people were looking that street. >> reporter: romero own as store in south san francisco. late afternoon he heard a commotion outside. >> i saw exactly when this guy, when the police was chasing him. this guy turn around and hit him with a skateboard in his face. >> this is video from a camera outside. he points out a person on a skateboard and what appears to be a foot chase. shortly after he says the suspect hit the officer. an officer he described as friendly. >> we know him. he used to pass by once in a while, say hi to us. i feel sorry for him, for his family and for all the police department. >> reporter: they say officer robby chon is a 12-year veteran of the department, married with two children. >> he underwent emergency surgery for traumatic head injury. >> reporter: the initial call was of a man acting aggressive and irrational. >> this city will not tolerate any violence directed towards its police forces. >> reporter: they arrested luis alberto reyes. and he's facing multiple charges including attempted murder oan police officer. >> when something like this happens it effects every 1 of us. >> reporter: and he took time note the out pouring of support his department has gotten from the community. all right. thank you very much. and black friday turning deadly in nevada after a road rage incident and a confrontation led to a shooting. and all over a parking spot in front of a walmart in reno. both had guns, one of the drivers shot and killed the other man. no arrests have been made so far but despite the deadly encounter in the parking lot, the walmart stayed open. and shoppers came out in droves. stores all across the bay area opened this morning and some yesterday afternoon for black friday. elyce kirchner with different kinds of friday deals. a green friday push. what's that? >> reporter: it's a very different twist on black friday. i have to say there are so many shoppers and it's cold. people are out in full force. you take a look over here. you can see the crowds of people. we also found nontraditional retailers here in the east bay all trying to inties shoppers. on the hunt. is you get dragged along by your parents? >> yes. >> reporter: black friday shoppers started early. >> we had about 200 people come in. >> reporter: with crowds filling into the streets in downtown walnut creek, a frenzy to find bargains. >> right now i can't find my wife. >> reporter: at the bay street shopping center, smaller crowds but shoppers of all ages came out. what did you get? >> [ inaudible ]. >> reporter: not far from retailers a push to opt out of buying. they say it was built on a sacred native american burial site. >> we come out here every year to keep acknowledging our ancestors that are still buried here. and another twist on black friday. >> people are going to be here every day, black friday or pink tuesday. >> with legalization and the normalization of cannibis, we've taken an approach of a bit more traditional retail approach and starting to participate in the same holidays sales. >> reporter: back in walnut creek some are already looking forward to cyber monday. >> i have to find parking. >> reporter: and back here live you can see cars waiting on the street looking for parking. there is not many spots open at this hour and the stores will be staying open late, some as late as 10:00 p.m. this evening. i'm elyce. >> the time to go is at 9:00. early. and you've got to do speed shopping. a lot of traffic around livermore and 580. it's a little bit chilly, especially out towards the east bay. along 680, walnut creek and alamo. close to 50, 47 in lurinda. should see mid-40s tonight. increasing clouds will prevent our temperatures from dropping like we had in a few spots. and the winds will be picking up ahead of our weather system that will bring the biggest punch wind and rain wise early saturday morning. the radar should stay that way through 10:00 tonight and there's a wind off shore and even as the skies clear, look at the temperatures tomorrow. only upper 50s. tri-valley up towards vallejo. upper 50s around the peninsula. and into san francisco. it's really just one big microclimate for you. and yes rain at times for our outdoor events. we have ucla in town. tempertures in the low 50s. a better chance of showers at times in the stanford game right into the evening. note this is sunday forecast. raider game early afternoon. probably one of the dryer patches we'll see this evening. temperatures in the upper 50s. coming up we'll explain how the cool temperatures could bring snow to the higher peeks in the area. we'll have it for you in the next half hour. well from instagram posts to being featured in vogue, how a san forisko art. happening now a gruesome discovery in southern mexico where they found 32 bodies and nine human heads buried in a grave. they found the bodies yesterday where rival gangs are fighting. you can find that story on our home page. and donald trump and team u.s.a. those are the characters showing up in holiday decorations in japan. they usually decorate their homes with characters. as we've been showing you shaurpz are hitting stores in a mad hunt for the big gift. and some may hold dreams of a gucci gift. and a artist whose gucci dreams came true in an unusual way. >> reporter: for countless hours artists will toil away hoping for that one big break. >> impactexactly like that. >> reporter: but you might say the scenic route. >> i actually studied biology. >> reporter: she was inspired by things like nature and fashion. >> i just love natural forms and animals. >> reporter: even dead ones. >> my taxidermy mouse i taught myself how to do. >> reporter: she started drawing professionally with inspiration from her husband, artist jeremy fish. >> he's so passionate about his work. >> reporter: who also likes fashion. >> reporter: not long ago jade fish started drawing taro cards. >> i love the metaphor and symbolism. i was #sandra mccay lay. >> that's the creative director for the italian line gucci who apparently also looks at instagram. >> reporter: and he saw and was curious if i'd be open to gucci acquiring them. >> reporter: gucci bought fish's drawings and this fall they got invited to italy for the gucci fall fashion show. no idea. >> no. >> i was excited, nervous and mostly making sure she didn't explode. >> reporte >> a smoke filled room, dim filled lighting. >> and one by one they started coming down. >> reporter: and that's when the couple saw them. >> clothes go down that had my illustrations plinted on them. >> oh, that's an owl on that and they made patch on that. >> reporter: the same gucci that inspired fish was inspired by her art. >> you get an opportunity this big by literally using a hashtag of a dude's name. it seems impossible. >> like some kind of magical thing has happened to me. >> reporter: maybe these days the shortest distance between two points is fine art and a social media account. joe ruzaudo jr., nbc bay area news. >> that's pretty amaezing, right? she will open her first solo show on december 9th in san francisco. coming up, can a cancer diagnoses make your life better? we introduce you to a remarkable young woman living with stage 4 cancer. while she hates her disease, it's actually given her something back. that's next. the search is still on for the two inmates who escaped from the santa clara jail. only now the focus on santa clara and there are still strange twists that have not been solved. right now it's a search for these two escaped inmates has shifted from san jose to santa clara. as we've been reporting four inhad main inhi inmated escaped. >> robert handa went out with a search team and you've been posting and tweeting about their progress all night long. >> reporter: one of the things that many peopling were wondering about is how two got caught so easily while the other two disappeared so quickly. although as you've been hearing the search dogs have apparently picked up their trail. today they say search dogs picked up the scent of the prisoners. they led searches towards interstate 880 and santa clara. the trail took them to the tazman drive area near levi stadium. they're searching for julio chavez. this is video of chavez when nbc bay area coved a recent court proceeding. and the other inmate is 26-year-old campbell of palo alto. and one of the men captured immediately is 21-year-old desilva of santa clara who we recently showed as one of two men arrested for a violent home invasion in cupertino. >> i want to assure to community that we really are working around the clock. it's been an all-hands on deck effort. and we have looked into every public tip and asking for the public's help. >> reporter: the sheriff says along with the search in santa clara, they're still trying to figure out how they cut through the bars of the window and what was used in that and the sheriff says surveillance cameras will now be installed in this area of the the jail. >> we will continue to follow these developments on the manhunt on the air and online. just head to our website, nbcbayarea.com, for the latest news and we posted more pictures of the escapies there. a federal judge says the alleged gunman dillen roof is mentally fit to stand trial. he's accused of gunning down people at historical church last year. the judge will not release the transcripts because it might interfere with jury selection. and president elect donald trump has filled two more topped a madministration posts. she's been named the deputy national security advisor. campaign attorney donald mcgone is the choice for white house counsel. tributes continue to pour in today for the actress known as america's mom. flowers were placed on the hollywood walk of fame. she died at the age of 82 from heart failure. she's best known as her role on "the brady bunch." series. anderson was universally remembered as a really nice woman with firm midwestern values. she was the youngest of 10. >> she always came to visit when she could and kw even though she lived away all these years, we stayed pretty close touch. >> henderson's tv children mourned her today on social media. she also had four real children who were by her side. a cancer diagnoses is a devastating piece of news but one bay area woman is refusing to threat dev state her life. before she got sick she was a busy sillicon valley ceo working around the clock. now she's living with stage 4 cancer and in some ways has made her life better. >> why didn't i get it? >> reporter: for years ceo and president of the sillicon valley forum worked nonstop creating and supporting all kinds of technology. >> being a person always worked so, so hard, had such a career. >> reporter: in 2015 she was busy trying to get pregnant with her new husband when a fertility screening revealed stage 4 cancer. she was 37 years old. >> so when you get stage 4 cancer diagnoses you don't know how many yearess you have. >> reporter: not long after this life long workaholic stopped and says a new chapter of life began. >> the irony now is that i'm living my life more now. >> reporter: it's almost impossible to think of a cancer diagnoses making anyone's life better. but psychiatrist speegal says it can. >> it forces you to realize the trivial and evaluate what really matters the most. >> reporter: he's been studying the psychological effects of cancer. >> one patient says my life has never been the same. >> reporter: barny is the epitome of this idea. once a month she takes a trip all over the globe with people she loves. she's determined to live well. >> do i think it's wonderful she's telling a positive story. >> reporter: her oncologist says barny is one of her patients using it to her advantage. >> it almost always changes their out look. >> reporter: barny says don't get her wrong. she's very mad at her disease. >> and i'm really pissed off at cancer. >> reporter: but it's given her something back. >> what's the worst thing that can happen really in life? is that you die or someone near you dies or -- that's the worst thing that can happen and while you're alive, why be dead? >> reporter: she says this is the unwelcomed gift that some cancer patients accept. >> it cures neurosis. you realize some of the things you've been wasting on. >> i'm trying to live a life to the fullest. >> she says she'd rather not have cancer but the right response can give permission for people to live better. she's very incredible. >> she does sound incredible and a gift to everyone. not sure about your new black friday purchase? nbc bay area responds with tips if you need to pull off a refund. plus a delay for commercial crab season. take a look at this big mess on hollywood 101. a big postal mess here after a postal service employee was driving the big rig lost control of the truck. it flipped over on 101 just before 7:00 in the morning. paramedics rushed the driver to the hospital. he's expected to be okay. no other drivers were involved but they had to close down ramp for seven hours because postal workers are the only one whose can legally pick off mail off the roadway. justices ruled palo alto city counsel illegally put a measure on the ballot which would create binding arbitration. that's commonly used for disputes between fire unions. this week the court says it violated state law. it could ask the state supreme court to review the ruling according to the website. no doubt parking -- and they're reporting that a lawsuit has been filed to stop a 300 space parking lot near the popular parking trail. this claims that the park district did not look at alternatives and it could effect the golden eagle paop ylspopula. the commercial crab season was supposed to start december 1st. now they're recommending it be delayed indefinitely. as many as half of the ducngenes samples t s tested over the lim. california health officials say dungeness caught north of the oregon boarder, that did test safe. we're taking a live look outside and it is cold. >> it is cold. last couple of mornings we've had temperatures in the 40s and 50s. we're looking at rain, wind, a chance of thunder. what it means when we come back. before you return that unwanted gift learn where to look for your rights. nbc bay area respawns. all right on this black friday. we help viewers return merchandise and get refunds all year long. not every gift is ideal. >> no. we asked chris chmura to give us ground rules. >> our team has developed expertise in this and you might be surprised to learn that they're not 100% guaranteed by state law. the attorney general's office says they're not required by law to accept returned items unless they're defective. if the return policy contains limitations, the rules must be spelled out at? door, on registers or on tags. a return policy only on a receipt is not sufficient. you can also report them. call your local district attorney or the california attorney general. if you have a consumer complaint, you can call us. -888-996-tips or visit nbcbayarea.com/responds. well the winners are. we just announced the winners to our annual grand challenge. three bay area nonprofit organizations will be getting a total of $100,000. hack the hood will get 50,000. it's a 168 hour emrsive boot camp to learn about being an entrepreneur. and hispanic foundation of sillicon valley and finally juma ventures. they help them learn a livable wage while earning their degree. really neat foundation. very deserving of those foundations. man of the hour. when you go out, continue your black friday shopping, you should bring a? >> an umbrella and hang on. we're talking about the shopping. if it's rainy and windy, maybe themorning might be your time frame. we'll be watching that and for some spots tomorrow morning. right now no worries if you're outside trying to shop in the cool temperatures in san jose. should not be as cold as we've seen over the last couple of mornings. l low 50s. increasing clouds will keep our temperatures from getting chilly tonight. you can see the golden gate bridge. rain still lurking to the west given the cool temperatures and windy conditions. we have that beach hazard statement for high surf. now extended through 3:00 a.m. sunday. rip currents and sneaker waves on the coast. rain is not on the radar yet but starting to show up in the north bay and look at the effect on temperatures tomorrow. upper 50s and mid-50s through the trivalley. even as we see a few sunny breaks during the afternoon. you'll find the same in san francisco. chilly breeze at times out of the northwest and north bay temperatures in the mid-50s. so the time line you'll see as we're tracking two storms for the evening. moving through quickly and given the cold naturer of the storms not bringing a lot of rain. again it's really saturday morning we'll see the potential of wind and rain. and then for the afternoon partly cloudy skies. so improving conditions. we think a break between systems and saturday into sunday. there's the cooler going down the coast. could see a dusting of snow near mt. hamilton and given the cool nature of the two storms, isolated thunder a possibility for tomorrow morning and saturday into sunday. this is the time frame. a windy and rainy start. we think the saturday improving conditions by the afternoon. more rain saturday into early sunday and chilly and breezy midafternoon sunday and there you go. a third system by sunday into monday. winter storm warnings could see maybe as much as two feet of snow above 6,000 feet. as the systems are probably the coldest we've seen this far. so you'll be spending more miles driving through the snow as you can see the cool air this weekend. so we'll be looking at widespread wind and rain. more rain saturday into early sunday. maybe a few showers towards the middle part of the week but we're looking at really chilly temperatures and we'll have to see if mt. hamilton gets snow posaelk sibly by sunday morning. >> and when it does it's really beautiful. klay thompson has his groove back. coming up next in sports. happy friday. i'm mindy balk at the xfinity sports desk and the warriors are in los angeles seeking a 10th straight win against a lakers team may beat by 40 points just two days ago. their sharp shooter, klay thompson, he's back. we sat down with klay to find out how he developed his smooth shot. >> you are such a phenomenal shooter. i'm sure kids are wondering when you were growing up, were you a backyard shoot snr. >> there was a middle school down the street from where i lived and they had double rims. so in high school, 18, i would always go down there and shoot every day after i got home from school. because the double rims, it has to be a perfect shot to go in the hoop. tell kids that's how i developed the arc and jumper. you go to the park you miss out on that double rim. >> in new york, when we actually got to play in an indoor gym it was like a luxury and the shot went down a lot more. >> it made you better. it's fun being outdoors playing in the heat. playing on the playground in the park. >> do you know about park basketball life? you're from oregon so was there a big culture like that? >> no. we just go to the gym. you would summertime though. i was lucky enough to have a hoop. my dad and my grandpa, mostly my grandpa erected a hoop in our driveway. we were very lucky to have that. mostly my grandpa. 90% gramps, 10% pops. i think he just put the net on or something. >> what is it about the thompson genes. all of you have been proathletes in some way. baseba baseball, your brother probasketball as well. >> i think we love sports so much and having two brothers close in age was awesome because we competed and made each other better. play three on three, play football and even when i'm done playing i always have such a passion for sports whether it's table tennis or golf or basketball. i love to compete in something and we've been playing professionally in california. we're so close and we can all see each other play. it's been real nice. >>ers at the sharks. burns and mar low combined for the game winning goal. sharks win 3-2 and win their third straight game on home ice. so we're going to bring you all the highlights from tonight's warriors game at 11:00. even though they destroyed the lakers on wednesday night. they've lost their last two at staples. there's some voodo at that place. we'll see you tonight. >> looking forward to it. we'll keep our fingers crossed to make sure the voodo goes away. tonight at 11:00, the day two of searching and still no sign of the two missing inmates. we talk to a family of one of the inmates.. t that story and more at 11:00. evening plans just fine. outside we have clear skies, partly cloudy in san francisco. but you can see the rain on the doorstep. wind and rain for the morning and scattered showers for tomorrow afternoon and cold air, maybe cold enough for snow by early sunday morning. >> i just want to stay home and not shop. >> that's right. i like that idea. >> that's going to do it for us tonight at 6:00. we hope to see you at 11:00. our final interview with florence henderson. >> you have to live your life. >> her surprise passing just days after appearing on "dancing with the stars." now on "extra." ♪ ♪ here's the story of a lovely lady ♪ >> she was america's mom on the brady bunch. florence henderson gone at 82. the heart condition she'd been treating for years. >> i wound up in the emergency room. >> and from her tv kids, barry williams and maureen mccormick to her dancing family -- >> i loved her dearly. >> we remember the beloved mrs. brady. the legendary warren beatty on his first film in 15 years and being married NBC Bay Area News at 6 NBC November 25, 2016 6:00pm-7:01pm PST Local news, sports and weather. Gucci 6, San Francisco 5, California 4, Barny 3, Chavez 3, Donald Trump 3, Lakers 2, Raiders 2, Robby Chon 2, Thompson 2, Hamilton 2, Florence Henderson 2, San Jose 2, Hollywood 2, Mendocino 1, Desilva 1, Dillen 1, Oakland Mayorer 1, Donald Mcgone 1, Henderson 1 Uploaded by TV Archive on November 26, 2016
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Coach: Guard Darius Thompson to transfer from Virginia Virginia guard Darius Thompson is transferring, making him the third player to leave the Cavaliers men's basketball program in two days. Coach Tony Bennett made the announcement Thursday, one day after announcing that guard Marial Shayok and forward Jarred Reuter are also leaving. ''Although you never want to see young men transfer, I understand this is part of coaching,'' Bennett said in a statement. ''Darius, Marial, and Jarred feel it's in their best interests to pursue other options for the remainder of their college careers. I will always appreciate the contributions they made to our program.'' Thompson transferred to Virginia after spending his freshman season at Tennessee. He played for the Cavaliers for two years and started in 15 of his 33 appearances this year. He averaged 6.2 points in 20.8 minutes per game and 5.2 points over 70 career games at Virginia. Bennett said Thompson will transfer after graduating, making him eligible to play immediately wherever he lands. The defections are not the first for Virginia under Bennett. Virginia lost four players - KT Harrell, Will Regan, Billy Baron and James Johnson - from Bennett's initial recruiting class in 2009-10. Paul Jesperson left in 2013 after he started 33 of 35 games, and B.J. Stith left in 2015. ''As a staff, we are focused on finding student-athletes who want to be a part of this program and all the University of Virginia has to offer,'' Bennett said. Thompson, like Shayok, got inconsistent playing time this year, but averaged 34.5 minutes in the Cavaliers' two NCAA Tournament games. He also averaged 22 minutes in their two ACC Tournament contests, and had played as much as 20 minutes just three times in the 11 games leading up to the postseason. Virginia (23-11) reached its fourth consecutive NCAA Tournament this season and has been ranked in the Top 25 for 64 consecutive weeks. The departures leave Virginia with just six players on the roster who received significant playing time this season. Of the players returning, senior forward Isaiah Wilkins, senior guard Devon Hall and junior forward Jack Salt have been consistent starters, and sophomore guards Kyle Guy and Ty Jerome received significant playing time. Redshirt sophomore forward Mamadi Diakite played less consistently, but started the final game of the season. He will compete with highly touted freshmen guard De'Andre Hunter and forward Jay Huff, who both redshirted this season, for playing time next season. The school also will add incoming freshman guard Marco Anthony of San Antonio, Texas, into the mix. More AP college basketball: www.collegebasketball.ap.org Follow Hank on Twitter at: www.twitter.com/hankkurzjr More College Basketball Isaiah Wilkins Mamadi Diakite
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RIM makes ‘Bold’ move and creates US$150m app fund 12 May 200830 Views Research in Motion (RIM) has introduced a new BlackBerry smart phone called the ‘Bold’ phone and at the same time has created a US$150m fund aimed at encouraging a slew of innovative, third-party mobile applications from the software world. It emerged this morning that RIM has joined forces with Thomson Reuters and RBC Venture Partners to create a US$150m venture capital fund to focus on applications and services for the BlackBerry platform and other mobile services such as payments, advertising, retailing and banking. The company said the fund will be agnostic to both stage and balance sheet and it will not restrict the development of mobile applications and services to any single platform or any specific industry segment. Instead, it will focus on encouraging entrepreneurial spirit and creating the most innovative new mobile offerings. “The mobile world has evolved well beyond phone calls and simple messaging to require more empowering and liberating solutions that connect people to everything that matters most to them, wherever and whenever they want,” said Jim Balsillie, co-CEO, RIM. “RIM, RBC and Thomson Reuters share the common belief that mobile applications and services will propel the industry forward and the BlackBerry Partners Fund is being formed to help fuel innovation and activity in the mobile ecosystem.” Coinciding with the launch of the new fund was the unveiling of the much anticipated new BlackBerry device entitled ‘Bold’, the company’s first tri-band offering with HSDPA 3G connectivity. It also represents the company’s most style-conscious outing yet, with the device featuring satin chrome and a leather-like backplate. “The new BlackBerry Bold represents a tremendous step forward in business-grade smart phones and lives up to its name with incredible speed, power and functionality, all wrapped in a beautiful and confident design,” said Mike Lazaridis, president and co-CEO, RIM. The device will come with a 2-megapixel camera and a media player with an equalizer that features 11 preset filters from Jazz to Lounge to Hip Hop. The device also features software that allows quick and easy synchronisation of users’ iTunes libraries. The Bold will also come with a half-VGA colour LCD screen and a new display format for HTML web pages that allows users to choose between full desktop-style web content or the mobile version. As well as tri-band and HSDPA, the Bold comes with a Wi-Fi radio as well as GPS mapping functionality. The company said the phone should be available worldwide from various carriers from this summer. Related: funding and investment, iTunes, BlackBerry CitySwifter en route to digitally transform bus journeys Be part of a globally successful team A dynamic and rapidly expanding company Table4one gives business travellers food for thought Parkpnp founder Garret Flower on what drives an entrepreneur 1 hour ago25 Views Dundalk’s Diaceutics to list on London Stock Exchange with £53m market cap Dublin’s WarDucks raises €3.3m to develop new AR game title
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New Renault Clio Unveiled: UK Sales Start 2013 July 3, 2012 Roland 0 Comments new cars, Renault Clio The New Renault Clio - on sale in 2013 in the UK For anyone under the age of, say 35, the Renault Clio is probably the French marque’s most distinctive and popular model. It’s been around since 1990 and has sold more than 11.5m units in that time — placing is firmly in the premier league of small cars. Today, Renault unveiled the all-new fourth generation model of its ever-popular small car — a model that will play a decisive role in the company’s future success. Papa et Nicole Back in the dark ages 1990s, Renaults ‘Papa and Nicole’ television adverts for the Clio gave the car a sexy French appeal that the Ford Fiesta, good as it was (better, in fact), could not hope to match. Renault is clearing hoping for the same result this time, as this quote from the Laurens van den Acker, the company’s Vice President of design, shows: “New Renault Clio was conceived as a piece of sensuous sculpture which stimulates desire. Like muscles, its curves express the dynamism radiated by the DeZir concept car. No acute or aggressive angles, just voluptuous curves that make you want to go up to it and caress it.” Oooh, I say. That’s enough- what’s it really like? The good news is that Renault’s quality is better than it used to be and some of its latest engines are really pretty good. The styling of the car reminds me of a scaled-down version of the current Megane and looks pleasing enough to my eye. Some of the highlights of the new model are: New engines with low CO2 and impressive fuel economy The first Renault three-cylinder turbocharged petrol, the 0.9-litre TCe 90 Also available with 1.2 TCe 120 (petrol) and 1.5 dCi 90 (diesel, up to 88mpg) New technologies: R-Link integrated and internet connected touchscreen tablet, rear parking camera and R-Sound Effect app EDC (Efficient Dual Clutch) transmission offered for first time in Clio Five-door model only, including Renaultsport On average, 100kg lighter than predecessor The inside looks more luxurious than any of its predecessors and is is the norm, the new Clio is wider and longer than the model it replaces. I expect it will do well when it goes on sale in the UK early next year. Nicole? Papa! 25 -years of the Renault Clio Updated Renault Clio offers new engine choices New Renault Mégane: prices and specifications Is the diesel decade over? Car buyers opting for petrol,… Suzuki S-Cross gets mid-life facelift ← EU Tyre Labelling Launch Begins Sat Nav Review: TomTom Via 135 UK & Ireland →
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Home > Blog > Alumni > SkillsUSA Alumni News: December 2018 SkillsUSA Alumni News: December 2018 Posted December 17, 2018 in Alumni Like Icing on the Cake: For Its Pastry Program, Restaurant Group Focuses on SkillsUSA Hires Pictured above, top row, left to right: Heather Carpentieri (state-level competitor), Josie Wolfe (past national officer and national medalist), Sierra Slocum (regional competitor); bottom row, left to right: Jacqueline Mearman (SkillsUSA Alumni and Friends executive board Region 1 representative and national medalist) and Kaylin Braun (new volunteer/state-level judge). Executive Pastry Chef Jacqueline Mearman is a SkillsUSA professional partner intentionally hiring SkillsUSA alumni based on the personal, workplace and technical skills gained from participating in SkillsUSA. The company currently employs three alumni. Two of them, Sierra Slocum and Heather Carpentieri, are former state competitors; a third, Josie Wolfe, is a past national officer and national competitor. Thanks to the skill sets of these alumni, Atlas Restaurant Group has elevated its pastry program by including cutting-edge, multi-cuisine desserts and a special-order program for cakes. It’s Payback Time Advisor of the Year Joyce Price admits she has faced challenges running a SkillsUSA chapter. “But I always say it’s not about me. It’s about the kids. It’s always about the kids.” A cosmetology instructor and chapter advisor at Blacksburg (Va.) High School, Price has many accomplishments that reflect her commitment. The former student member has been active in SkillsUSA for more than 34 years. “I started as a student, and I’ve continued to stay involved throughout my career,” says the detail-oriented advisor. While working in industry, Price judged SkillsUSA competitions and attended district, state and national conferences. After becoming an advisor, she connected back to her passion for the organization and even earned its elite International Degree. Price says she wants to show her students what the organization can do for them, too, while helping each of them seek personal success. “I try to share with students my passion for SkillsUSA.” She has been invaluable to the state leadership as well, serving on the SkillsUSA Virginia board of directors and as the state officer trainer. She is also a district chair and is active on the planning committee for the state leadership conference. Price is proud of the many district, state and national officers she has prepared over the years. The state certified trainer has mentored 16 state officers, four national officers and worked with 10 national officers for SkillsUSA Virginia. A true professional who exhibits extraordinary teaching and leadership skills, Price is dedicated to both her students and community. Her cosmetology students participate in SkillsUSA’s Week of Service. Their projects include working with the Girl Scouts and providing free haircuts for needy children. “We give the county Department of Social Services coupons for haircuts that they can hand out to their clients,” Price explains. Members also participate in a service program called Mika’s Backpack. “We help pack up food supplies to send home with students in need, so they have enough food and snacks for after school and weekends,” Price adds. Her chapter also has a lot of ongoing projects with local veterans’ groups. The instructor looks for real-world experiences that teach time and project management while enhancing students’ technical skills and communication. To build an outdoor classroom and community garden, Price wrote an application and received a $10,000 SkillsUSA/Lowe’s grant for the school. Two of her students served as project managers. “Lowe’s employees helped us plan it, and our drafting department helped design it,” she points out. Everyone in the area can now enjoy the classroom and garden. “The agriculture department helps maintain it, the culinary department hosts events there, and it is available for the community to use. It’s been a great asset for the community.” CTE Signing Day a success Price accepts the trophy from her student Hunter Radford and award sponsor Air Products’ Shannon Byrne. In a new public relations effort, Price and her students were involved in a CTE Signing Day, similar to the events held for sports teams. “Athletes get all the attention, but we thought our students should get attention, too,” the advisor explains. “We worked with the county and had great media coverage. We work with the media on a lot, and I try to stay as involved in the community as I possibly can.” Price is fortunate to have support from the school administration and other instructors, but she accepts that not every teacher wants to invest so much personal time into the SkillsUSA chapter. Raising money is also an issue. “There’s always fundraising,” she notes. “You work at it because we have to do it. As long as you stay positive and you promote your program, that’s the key.” Because Price embraces a balanced SkillsUSA program of work, she gets involved in all its programs, from competitive events to the SkillsUSA Career Essentials suite and the Chapter Excellence Program. SkillsUSA has recognized her program as a Gold Chapter of Distinction for the past three years. Her greatest accomplishment As much as Price is proud of the state and national recognition garnered for her school, she cares more about the individual lives she can touch. She remembers being a high school student herself and knows how one teacher’s support can make a huge difference. “I’ve been involved in SkillsUSA for 34 years, and my teachers always encouraged me,” she says. Price recalls a recent student who had very little ambition. “The first day this student entered my classroom, she stated that she didn’t know what I could possibly do for her. I told her not to worry, because she would become a licensed cosmetologist.” After doing just that, her student is now enrolled in further schooling to get her esthetician’s license. She also became one of the strongest state SkillsUSA officers Price has ever had. “I’m especially proud of her because her mom told me she was bullied at school and didn’t have much self-confidence. She is now a totally changed person,” Price asserts. “Any student can benefit from this organization.” While this SkillsUSA advisor of the year, Sunday school teacher, mother of two and grandmother of four puts many hours into the program, she gets back more than she gives. “To me, it’s not work,” Price says. “I’ve always told myself if it becomes a job, it’s time for me to stop. It’s not a job. It’s a passion.” Contact Your State Association to Volunteer at Upcoming Events Are you interested in serving as an alumni volunteer for your SkillsUSA state association? Contact your state association director to get involved. Your help is needed, especially during state conferences. A list of state directors and their contact information can be found at: www.skillsusa.org/about/state-directors/. Alumni and Friends Executive Board Members for 2018-2019 Executive Chair: Jim Rhodes, New York Region 1: Jaqueline Mearman, Maryland Region 2: Denise Walker, Florida Region 3: Jill Brebeck. Wisconsin Region 4: Andrea Arbogast, Kansas Region 5: Richard Gautier, Nevada Executive Secretary: Ashley Hickey, South Carolina Eric Hill, SkillsUSA Illinois State Director Katie George, Business and Industry Representative from CareerSafe The Alumni Executive Board and national headquarters staff would like to hear from you. Your success stories inspire current SkillsUSA members. We’d also like to hear ideas and suggestions for growth and alumni program improvement. For more information, email Taryn Zeigler at tzeigler@skillsusa.org.
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TCL P607 55" (55P607) vs Sony X900F 55" (XBR55X900F) When comparing TCL P607 55" (55P607) vs Sony X900F 55" (XBR55X900F), the Slant community recommends TCL P607 55" (55P607) for most people. In the question“What are the best TVs?” TCL P607 55" (55P607) is ranked 3rd while Sony X900F 55" (XBR55X900F) is ranked 110th. The most important reason people chose TCL P607 55" (55P607) is: At $650, it's hard to find a better deal for a 55-inch 4K TV that can also handle HDR content reasonably well. Compared to its direct competitors, its picture quality is more or less similar to them. Although the HDR performance is just a tad below them, it's still great, especially for the price. It's also more versatile because it has better features for gaming - the input lag of ~15ms is among the lowest in 4K TVs on the market, and it has a motion blur of ~12ms that stacks up to more expensive options. The screen size is large for the price when compared to TVs in this price bracket, such as the Sony X900E which costs ≥$250 more for the 49" model. Dolby VisionYes What are the best 4K TVs for movies around $1000? What are the best TVs for gaming around $1000? What are the best 4K TVs around $500? What are the best TVs for gaming around $500? What are the best 4K TVs for movies around $500? No other questions Sony X900F 55" (XBR55X900F) At $650, it's hard to find a better deal for a 55-inch 4K TV that can also handle HDR content reasonably well. Compared to its direct competitors, its picture quality is more or less similar to them. Although the HDR performance is just a tad below them, it's still great, especially for the price. It's also more versatile because it has better features for gaming - the input lag of ~15ms is among the lowest in 4K TVs on the market, and it has a motion blur of ~12ms that stacks up to more expensive options. The screen size is large for the price when compared to TVs in this price bracket, such as the Sony X900E which costs ≥$250 more for the 49" model. Excellent picture quality The P607 looks true-to-life with lots of details. There’s a great depth to pictures and you’ll be able to see everything stand out. Dark scenes are great and you won't miss out on any details, even in shadows. The panel has a contrast ratio of about 6500:1, which means it can produce blacks that are 6500 times darker than the brightest white. This can be pushed even further to over 7000 with local dimming. Even in a decently-lit environment, the P607’s picture quality can still hold up - the panel is great at handling reflections and it can get bright enough to fight off glare. Main interface has no ads The P607 has no ads on its main interface, although there can be ads in third-party applications. Third-party ads can't be blocked, but the tracking and personalisation can be limited through the TV's settings. Excellent at upscaling low-res content The P607 can upscale 480p, 720p, and 1080p content to 4K very well. The upscaled content has almost no artifacts, and the crisp details are preserved. Supports both HDR10 and Dolby Vision formats The P607 can play both HDR10 and Dolby Vision content. Intuitive & smooth user interface The P607 runs on the Roku TV smart platform, touted for its simple, straightforward, and lag-free UI. It’s easy for anyone to grasp how navigation works, thanks to its two-column design with the menu on the left and options on the right. There’s also no noticeable lag during navigation or menu selection. Decent at handling glare In a decently-lit environment, the P607's colors won't look dull thanks to the panel's high peak brightness levels and decent handling of reflections. It's bright enough to fight off glare with peak brightness levels of ~500 nits for both SDR & HDR, and the intensity of reflections are also reduced by panel's semi-gloss finish. Great for gaming The P607 has low input lag and barely noticeable motion blur, making for a responsive and fluid gameplay experience. The input lag is barely noticeable at ~15ms for both SDR & HDR inputs, and the panel only requires ~12ms to fully change the pixels color, resulting in fast-moving objects not leaving any trails on the screen, eliminating virtually all motion blur. Great color accuracy The P607 is excellent at reproducing colors accurately out of the box. Even without calibration, the colors are spot-on. They're very close to what the source signal demands, and any inaccuracies are generally considered imperceptible to most end users. The overall average difference between the source signal and the panel's reproduction of the color is measured in Delta-E, where lower means better accuracy. The P607 has a Delta-E of below 2.0, and anything below 3.0 is generally considered accurate for most end users. Great for HDR content On top of its excellent picture quality, the P607 has everything essential to a great HDR experience: local dimming, wide color gamut, and fairly high peak brightness level. Highlights will really stand out as the deep black levels are further improved with local dimming. It can make parts of the screen darker when the image calls for it, resulting in a fairly huge boost in picture quality as the black levels become deeper. The wide color gamut enables the panel to reproduce the full range of colors required for true HDR playback. The screen can get sufficiently bright at a peak level of ~500 nits to light those colors up and make HDR details really pop. Great overall picture quality The overall picture quality of the Sony X900F is on par with what the best, high-end TVs in its price range offer. The X900F offers excellent performance when it comes to both bright and dark scenes thanks to its ability to recreate bright and vivid colors as well as some deep blacks. Exceptional smoothness of motion The Sony X900F does an excellent job of reproducing smooth and fluid motion thanks to its advanced flickering capabilities. The panel can flicker at the rate of 720 Hz which can eliminate motion blur. Only a few panels in this price range can flash that fast, which is good, as the majority of viewers will not notice such fast flickering. Additionally, unlike the overwhelming majority of TVs present in this price range, the X900F can perform local flickering which ensures that the flickering doesn't take its toll on the overall brightness. Worth noting that the regular flickering of an LED panel reduces its brightness by about a half which can de-saturate some highlights and degrade the image. The sound quality on the P607 is terrible. It sounds unclear, and there is noticeable distortion at higher volumes. A cheap soundbar is highly recommended to get the most out of this TV. Local dimming can be quite aggressive In very bright scenes, the local dimming can be too aggressive and make black spots really dark to the point where some details are lost. The P607 has poor viewing angles that makes it unsuitable for group watching. Its picture quality gets progressively worse when viewed further away from the center of the screen. At just ~10° away from the center, the blacks start degrading into grays, and colors will start looking dull at beyond ≥20° from the center. Not suitable for sports The color uniformity of the P607 is quite poor, and the viewing angle is narrow. When displaying large same-color objects, such as football or hockey fields, certain areas of the screen will look darker than the others, resulting in uneven colors. This becomes worse when paired with the bad viewing angles that makes the picture quality deteriorate even further, and also makes it unsuitable for watching sports with a group because the picture quality won’t be consistent to all viewers. Comes in only one size (55-inch) Currently, the P607 only has a 55-inch model available on the market. Doesn't look good from an angle The TV's picture quality degrades noticeably while viewed from an angle. Samsung Q8FN 55" (QN55Q8FN) TCL S405 55" (55S405)
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Antistresové omaľovánky Dekoratívne umenie Súčasné výtvarné umenie Štýly a hnutia Umelecké monografie Dejiny výtvarného umenia Edvard Munch: love and angst Edvard Munch (1863-1944) is best known today as a painter, but his reputation was in fact established through his prints, which were central to his creative process. His printmaking was experimental and innovative, and he continually revisited the subjects of his paintings in striking prints, in which he evoked a wide range of emotion and mood through the use of varied techniques. Munch's early life in the industrial town of Kristiania (renamed Oslo in 1925) was marked by sickness and poverty. His first works centred on the expression of deep emotional experiences, specifically the deaths of his mother and teenage sister when he was growing up, as well as passionate yet unhappy love affairs of which his deeply religious father disapproved. Encouraged by his encounters with a Bohemian society of artists, writers and poets, he developed a visual landscape that was a radical deviation from the slick society portraits and grand Scandinavian landscapes then so much in vogue. His efforts attracted considerable attention and much criticism, and he practised with little financial success as a painter for ten years before he started to gain his reputation as a profoundly innovative printmaker. Written by a team of acknowledged experts, and with an interview by writer Karl Ove Knausgaard, this book will shed new light on the production of some of Munch's most remarkable works. tvrdá Hiroshige, Kisokaido Andreas Marks, Rhiannon Paget Ingo F. Walther Leonardo 25 kr Prof. Dr. Frank Zöllner van Gogh 25-gr The Early Picasso
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Home Outdoors Eating through the mountainside Eating through the mountainside by Holly Kays Holly Kays photo Ila Hatter Ila Hatter explains the mysteries of the walnut to her audience. I spent a significant part of my childhood wanting to be Sam Gribley, the boy in Jean Craighead George’s “My Side of the Mountain” who runs away from the city to live in a hollowed-out hemlock tree. I thought seriously about seeking out a hemlock of my own, eating cattail tips and wild apples, reading by a turtle-oil lamp. Only two things stopped me: I liked my friends, and I liked my mom’s cooking. I’m pretty sure the latter wouldn’t have stopped Ila Hatter, a Smokies naturalist who’s one of the best around when it comes to knowing how to find a snack in the woods. It was several months ago that I first heard Hatter’s name pop up in an announcement about an edible plants tour, and I’d been waiting for my opportunity to have this fellow plant-lover introduce me to our botanical neighbors. “Whatever new place you go to, it seems like in about three years, you begin to understand the land and the land begins to understand you,” Hatter said as she began a tour of the edibles on Western Carolina University’s campus. Hatter, 72, has dedicated decades to learning the leafy landscape of the Smokies. She knows what’s safe to eat, what’s good as medicine and how to prepare it. But she doesn’t know it from books so much as from story and experience. “I think that the stories make learning more interesting, whether you’re learning about plants or anything else,” Hatter said. “It also makes a walk in the woods like a visit with our friends.” At her home in Bryson City, N.C., Hatter makes elderberry syrup and saves spicebush berries in addition to stocking food from the grocery store. She picks lamb’s quarter for salad greens and gathers wild blackberries. She understands the land, but she’s quick to point out that she’s not a trained botanist—she’s still gathering knowledge as well as plants. That’s knowledge I’ve been hunting for since returning to the Appalachians from a jaunt out West. For me, knowing the plants around me is key to feeling at home, so I listened closely as Hatter pointed out the black walnut tree, a stalwart of Eastern forests, infamous for the permanent inky stain surrounding the edible nut. For the Cherokee, Hatter said, a warm dish of corn, hominy and black walnuts is a staple, with cushaw pumpkin chunks thrown in on special occasions. “It’s a really good combination,” she said, adding that she doesn’t much care for the pumpkin kind. There’s the elderberry, whose dried flowers make delicious fritters when fried in pancake batter and whose berries yield powerful antiviral syrup, and dandelion’s host of uses include salad green, wart remover and caffeine-free coffee. Dogwood berries often were used during the Civil War to break soldiers’ fevers, Hatter said, and a cut grapevine can release a gush of fresh water, welcome to a thirsty hiker. Then there are the non-food uses, just as vital for survival-oriented ventures. Hatter pointed out the sycamore tree, which disburses its seeds in tight, round balls. “One of the things we tell children is that they’re buttons in the woods,” Hatter said. At the center is a hard little ball attached to the stem holding the seed to the tree. Hunters used to look for sycamores to replace lost buttons during a hunt, Hatter said. Cherokee people used to roast the acorns of white or chestnut oaks—red oak acorns are much more bitter—and grind them into flour, which Hatter recommends mixing half-and-half with regular white flour. Spicebush berries were ground up as allspice flavoring, the outsides of the berries grated off for pepper flavor, and wild game boiled with the twigs. For Hatter, the process of collecting this knowledge and learning the stories behind it has been the work of a lifetime. It takes investment in people to learn their lore. “You have to have a good relationship with folks before they’ll share something like that with you,” she explained. Hatter’s now at home both in the forest and in the houses of the people who have unveiled it for her, a win-win in terms of both food and friendship. I’m still a long way off from creating either elderberry syrup or a mental encyclopedia of botanical lore. But it’s hard to spend a day with Hatter and not have some of it rub off—I went home and promptly found some lamb’s quarter to top my homemade pizza. food nature No comma between corn and hominy, please. Hominy is corn, or to be succinct, it is "corn hominy". ;-) Kit Goodwin more than 3 years ago
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The Southern Foodways Alliance documents, studies, and explores the diverse food cultures of the changing American South. Gravy Podcast The SFA team is extremely excited to announce a brand new Southern Foodways Alliance audio initiative, launching later this year. Gravy: Stories from the Southern Foodways Alliance expands the Gravy brand—already established in print—to a bi-weekly, narrative podcast. Like all of the SFA’s work, Gravy shares stories of the changing American South through the foods we eat. It brings smart Southern narratives to a national audience, revealing the region in all its complexity, telling true and sometimes difficult stories of Southern pasts and presents. Gravy showcases a South that is constantly evolving, accommodating new immigrants, adopting new traditions, and lovingly maintaining old ones. It uses food as a means to explore all of that, to dig into lesser-known corners of the region, complicate stereotypes, document new dynamics, and give voice to the unsung folk who grow, cook, and serve our daily meals. Through the window of food, we glimpse how race, class, gender, faith, and environment play out in the region and across the nation. Gravy tells stories of farmers and food scientists. Of dishwashers and distillers. Of banh mi and barbecue shrimp. Of your grandma’s potlikker and your neighbor’s arroz con pollo. Of the mariachis singing in the fried chicken café. And the punk band playing the vegan joint. This is the South you know, and the one you have not have tasted before. Joining the SFA in this effort is Tina Antolini, who will serve as Gravy‘s producer and host. A native of Maine who has chosen New Orleans as her adopted home, Tina holds a BA in American studies and ethnomusicology from Hampshire College. She’s also an alumna of the radio program at the Salt Institute for Documentary Studies in Maine. Tina has produced stories for a variety of radio programs, most recently as the senior producer of the NPR show State of the Re:Union. She has reported on topics ranging from Lenten alligator in Louisiana to nonagenarian transgender women in Massachusetts. Gravy launched in late November 2014 with a Thanksgiving-themed episode and will bring listeners a new story (12-20 minutes in length) every two weeks. The show will be available to stream or download at no cost to the listener. We are grateful for the work that outgoing oral historian Amy Evans and former Nathalie Dupree Graduate Fellow Anna Hamilton did with our first audio series. You can listen to more here.
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Act 3 Scene 2 Page 6 Five Key Questions What Does the Ending Mean? Act 2, prologue–scene 1 Act 2, scenes 2–3 Video Plot Summary Friar Lawrence Mercutio Main Ideas Plot Analysis Foreshadowing Are Romeo and Juliet really in love? Important Quotations Explained Quotes By Character Friar Laurence What did Shakespeare’s audience know about Italy? Why are there sonnets in Romeo and Juliet? Movie Adaptations Full Book Quiz Themes Motifs and Symbols Companion Texts Sample A+ Essay How To Cite No Fear Romeo and Juliet Act 3 Scene 2 Page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Act 3, Scene 2, Page 5 Table of Contents Characters Act 1, Prologue Act 1, Scene 1 Act 1, Scene 2 Act 1, Scene 3 Act 1, Scene 4 Act 1, Scene 5 Act 2, Prologue Act 2, Scene 1 Act 2, Scene 2 Act 2, Scene 3 Act 2, Scene 4 Act 2, Scene 5 Act 2, Scene 6 Act 3, Scene 1 Act 3, Scene 2 Act 3, Scene 2, Page 2 Act 3, Scene 2, Page 3 Act 3, Scene 2, Page 4 Act 3, Scene 2, Page 5 Act 3, Scene 2, Page 6 Act 3, Scene 3 Act 3, Scene 4 Act 3, Scene 5 Act 4, Scene 1 Act 4, Scene 2 Act 4, Scene 3 Act 4, Scene 4 Act 4, Scene 5 Act 5, Scene 1 Act 5, Scene 2 Act 5, Scene 3 How to Cite Modern Text (gives the NURSE a ring)O, find him! Give this ring to my true knight, And bid him come to take his last farewell. (giving her a ring) Oh, find him! Give this ring to my true knight! And tell him to come here to say his last goodbye. Exeunt They exit. Read the Summary of Act 3, scenes 2–4 Romeo: Character Analysis Review Quiz
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Home » Supercars » De Silvestro lands Daytona 24 Hours drive De Silvestro lands Daytona 24 Hours drive By Tom Howard Saturday 13th October, 2018 - 1:52am Simona de Silvestro pic: AJP Photography Simona de Silvestro will contest next year’s Daytona 24 Hours after being named in an all female line-up for the IMSA WeatherTech SportsCar Championship opener. The Nissan Motorsport Supercars driver will team up with Katherine Legge, Jackie Heinricher and Ana Beatriz in a GTD class Acura NSX GT3 prepared by Meyer Shank Racing. While the team plans to field the car in the entire WeatherTech SportsCar Championship, de Silvestro is only confirmed to join the squad for the Daytona 24 Hours race from January 24-27. De Silvestro is due to enter the final year of her current Supercars contract next year. “It’s pretty exciting and I think for sure the line-up that we have is really strong,” said de Silvestro. “All of us girls have a lot of credibility and I think it will be quite exciting so I’m really looking forward to Daytona. I think the team dynamic will be very strong. “For myself, it will be a little bit of learning but I am looking forward to it. “It’s quite a special feeling to be a part of such a good team that has had a lot of success so I think this is going to be a great car to be in and to give us all a strong shot. I just can’t wait to go racing in Daytona, which I have always dreamt about.” The entry, backed by construction machinery manufacturer Caterpillar, will be the first time an all female team has entered the Daytona 24 Hours since 1967. De Silvestro is not the only Supercars driver to contest the event in recent years with the Swiss ace due to follow in the footsteps of 2016 Supercars champion Shane van Gisbergen, who has featured each year since 2014. Next Story Q&A: Richards on Bathurst win and Aus GT title shot Previous Story Stadium Super Trucks responds to CAMS, court judgement More Supercars News » Steven Johnson has no regrets over knocking back GRM » McLaughlin: Reynolds rivalry 'good' for the sport » Supercars objects to TCR Australia Adelaide 500 plans » LED info panels on Supercars wish list after Townsville trial » Percat victorious on single seater return » VIDEO: Enforcer & The Dude: Episode 6 » Percat lands late single-seater call-up » VIDEO: Key players speak about Junior Development Program » Supercars launches Junior Development Program » De Pasquale allowing Morris to steer 2020 future
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STYRIA sports platform SPOX lays the foundation for even more reach and sales ProSiebenSat.1 PULS 4 enters into a cooperation with Perform Austria and STYRIA and relaunches its digital agendas. The core of the cooperation: The entire PULS 4 SPORT content of Austria's leading private TV group will now be shown on SPOX.com, which will thus become the joint digital sports home of the three partners. UEFA Europa League (from 20.9.) and NFL (from 9.9.) live and exclusively on Free TV on PULS 4 and in the ZAPPN App as well as online on SPOX.com ProSiebenSat.1 PULS 4 concludes a cooperation with Perform Austria and the Styria Media Group and reorganizes its digital agendas. With the Perform Group, the broadcasting group brings on board the internationally leading player for sports media moving images, which operates the sports streaming platform DAZN, among other things. The core of the cooperation: The entire PULS 4 SPORT content from Austria's leading private TV group will now be shown on SPOX.com. Austria's leading private TV broadcasting group and one of the largest online sports platforms in the country are cooperating. Through the cooperation with SPOX.com, a joint project of the Perform Group and the Styria Media Group, ProSiebenSat.1 PULS 4 now offers a relevant sports page for Austrian sports fans and will further expand its reach together with its partners. In the future, all sports events for which PULS 4 SPORT holds exclusive license rights will also be shown there. Additional content supplier is the PULS 4 SPORT editorial office, which also produces current sports news together with STYRIA. SPOX.com offers the following highlights: - Livestream of all PULS 4 SPORT UEFA Europa League live matches - Highlights of UEFA Europa League and UEFA Champions League matches - Discussion and live stream of the PULS 4 NFL live game Alfred Brunner, Managing Director Styria Sport: "The sports portal SPOX Austria, which was only launched at the beginning of 2017, has got off to a super successful start with currently 2 million visits and over 6 million page views. The new strategic triple alliance of Styria SPORT, Puls 4 SPORT and Perform Group lays the basis for a further increase in relevance and thus growth in reach and sales. SPOX Austria users can look forward to many LIVE top games on SPOX.com". Michael Stix, CCO ProSiebenSat.1 PULS 4: "We are pleased to jointly build a high-quality, digital sports site with premium sports content and exclusive licensed content and to professionally extend the TV and mobile arm with PULS 4 and our ZAPPN app into the online sector as well". Mario Lenz, Head of Sports Content ProSiebenSat.1 PULS 4: "The cooperation offers us the opportunity to build up a more relevant sports site together with strong partners in Austria. With SPOX.com we can take our digital performance to an international level and reach even more people with our content". Haruka Gruber, Global Publishing Director von Perform: "We are very proud to have formed a partnership with two of Austria's leading print and TV media groups to strengthen and expand the SPOX brand in Austria. SPOX stands for premium content and is further enhanced by the live rights of PULS 4 SPORT and the highlight rights from the UEFA Europa League and the UEFA Champions League. With SPOX and DAZN as the leading sports streaming platform, Perform's footprint is unmistakable in Austria". Also on PULS 4 on ZAPPN: Current PULS 4 SPORT license rights - live on PULS 4, in the ZAPPN App and online on SPOX.com: ***UEFA Europa League*** 2018/19, 2019/2020, 2020/2021 - Launch: Thursday, 20 September ***National Football League (NFL)*** 2018/2019, 2019/2020 - Start: Sunday, 9 September
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How Do Baseball Stadium Dimensions Affect Batting Statistics? * Show Others Like This Time Required Short (2-5 days) Prerequisites Basic knowledge of Microsoft Excel, statistics, and baseball Material Availability Readily Available Cost Very Low (under $20) Safety No issues *Note: This is an abbreviated Project Idea, without notes to start your background research, a specific list of materials, or a procedure for how to do the experiment. You can identify abbreviated Project Ideas by the asterisk at the end of the title. If you want a Project Idea with full instructions, please pick one without an asterisk. Have you ever wondered how playing in a certain stadium affects how well the athletes perform? Major League Baseball (MLB) is played in ballparks that have their own individual quirks when it comes to the exact layout of the field. How an individual ballpark affects player performance, which is known as ballpark effects, is heavily investigated in the field of baseball. To name just a few parks and their different traits, Fenway Park (the long-time home ballpark for the Boston Red Sox in Boston, Massachusetts) has the famous "Green Monster" in left field, the original Yankee Stadium (located in the Bronx in New York City) was notorious for the "short porch" down the right field line, and Coors Field (in Denver, Colorado) is at a much higher altitude than any other ballpark. How do differences likes these and others affect batting statistics? One characteristic of a ballpark that you can use to compare it to others is the ballpark's dimensions. Figure 1 below shows a general baseball field layout. But even in modern baseball not all stadiums are the same size, and this can affect batting statistics. For example, a player who hits .300 with 30 home runs in one stadium may be a .250 hitter with 15 home runs in another ballpark. Figure 1. While baseball fields may have the same general layout, as shown here, not all of them are the same size and they often have their own individual quirks. How does this affect the players' performance? (Wikipedia, 2005.) In this mathematics science project, you will determine how the dimensions of a baseball stadium affect batting statistics. You will need to do a little digging to pull the numbers together, but a nice thing about this project is that the experiments are already done, and the data is out there waiting for you. (See the Bibliography in the Background tab for some resources to help you find this data.) For each ballpark that you are interested in investigating, find out what its dimensions are. Then look up the team's batting statistics at the home ballpark and at road ballparks over the time that they have been playing in that particular home ballpark. (Do this for their opponents as well.) After you have collected the relevant data, average the batting statistics for each team for when they played in the home ballpark or in a road ballpark. Since the average road ballpark is nearly the same as the league's average ballpark, the difference between home and road performance should be the home ballpark's effect on offense. How do the dimensions of a ballpark affect which ones are good hitter's ballparks, and which are not? You could also investigate how other factors, such as altitude, weather, and remodeling a stadium, affect how the athletes play. While altitude is easy to quantify since it does not change, matching weather data with batting statistics may be a bit harder and may require some programming. How does changing the dimensions of an existing ballpark, which sometimes happens when a stadium is remodeled, affect the players' batting statistics? For example, the Oakland Athletics' home ballpark used to have a lot more foul ground around home plate. How do you think doing something such as shrinking foul territory around home plate affects batting statistics? To investigate an effect such as this, you could select a group of players and analyze their batting statistics before and after the remodeling. You could even look at individual players to see if there are individual variations by hitting style. To investigate this, you will have to do some research to find out when changes were made, and what the ballpark dimensions were before and after remodeling. Share your story with Science Buddies! Yes, I Did This Project! Please log in (or create a free account) to let us know how things went. Gabriel Desjardins General citation information is provided here. Be sure to check the formatting, including capitalization, for the method you are using and update your citation, as needed. Science Buddies Staff. "How Do Baseball Stadium Dimensions Affect Batting Statistics?" Science Buddies, 19 Mar. 2018, https://www.sciencebuddies.org/science-fair-projects/project-ideas/Math_p003/pure-mathematics/how-do-baseball-stadium-dimensions-affect-batting-statistics. Accessed 16 July 2019. Science Buddies Staff. (2018, March 19). How Do Baseball Stadium Dimensions Affect Batting Statistics? Retrieved from https://www.sciencebuddies.org/science-fair-projects/project-ideas/Math_p003/pure-mathematics/how-do-baseball-stadium-dimensions-affect-batting-statistics Last edit date: 2018-03-19 Here are a few websites that will help you start gathering data on baseball parks, teams, and players for this science project: ESPN. (n.d.). MLB Statistics - 2012. Retrieved November 9, 2012, from http://sports.espn.go.com/mlb/statistics Mock, J. (n.d.). Major League Ballparks since 1900, sorted chronologically by franchise. BaseballGuru.com. Retrieved November 9, 2012, from http://baseballguru.com/joemock/ballparkchart.htm Looking for more big data science projects? Explore the World of Big Data with Your Science Project! News Feed on This Topic Note: A computerized matching algorithm suggests the above articles. It's not as smart as you are, and it may occasionally give humorous, ridiculous, or even annoying results! Learn more about the News Feed The Ask an Expert Forum is intended to be a place where students can go to find answers to science questions that they have been unable to find using other resources. If you have specific questions about your science fair project or science fair, our team of volunteer scientists can help. Our Experts won't do the work for you, but they will make suggestions, offer guidance, and help you troubleshoot. Science Fair Project Guide Other Ideas Like This Pure Mathematics Project Ideas Big Data Project Ideas If you like this project, you might enjoy exploring these related careers: Statisticians use the power of math and probability theory to answer questions that affect the lives of millions of people. They tell educators which teaching method works best, tell policy-makers what levels of pesticides are acceptable in fresh fruit, tell doctors which treatment works best, and tell builders which type of paint is the most durable. They are employed in virtually every type of industry imaginable, from engineering, manufacturing, and medicine to animal science, food production, transportation, and education. Everybody needs a statistician! Read more Life is full of risks to both people and property. Actuaries predict the chances that future negative events will occur in a person's life, and then think of ways to reduce those chances, or reduce the impact of those negative events. Actuaries help bring peace of mind to both families and to businesses. Read more Math teachers love mathematics and understand it well, but much more than that, they enjoy sharing their enthusiasm for the language of numbers with students. They use a variety of tools and techniques to help students grasp abstract concepts and show them that math describes the world around them. By helping students conquer fears and anxieties about math, teachers can open up many science and technology career possibilities for students. Teachers make a difference that lasts a lifetime! Read more Looking for more science fun? Try one of our science activities for quick, anytime science explorations. The perfect thing to liven up a rainy day, school vacation, or moment of boredom. Colorful Melting Ice Ball Patterns - STEM Activity Slippery Slopes - STEM activity How to Make Elephant Toothpaste Overall, how would you rate the quality of this project? Excellent Very good Good OK Poor What is your enthusiasm for science after doing your project? Very high High Moderate Low Very low Compared to a typical science class, please tell us how much you learned doing this project. Much more More About the same Less Much less What was the most important thing you learned? Science Buddies materials are free for everyone to use, thanks to the support of our sponsors. What would you tell our sponsors about how Science Buddies helped you with your project? Optional: Attach a picture of your project (JPG, JPEG, GIF, PNG only) Optional: Caption for picture You can find this page online at: https://www.sciencebuddies.org/science-fair-projects/project-ideas/Math_p003/pure-mathematics/how-do-baseball-stadium-dimensions-affect-batting-statistics
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Music review: Backstreet Boys, Glasgow Hydro Backstreet Boys PIC: Kevin Winter/Getty Images The buskers stationed in the covered walkway to the Hydro had boned up on their boy band repertoire and delivered stereo renditions of the Backstreet Boys’ teenybop classic I Want it that Way as a stripped-back taste of treats to come. And there was a lot to gorge on. Backstreet Boys, Glasgow Hydro *** Unlike their fellow man bands, this Florida five-piece have never formally split up, so there were 32 more tracks where that came from on their bumper DNA tour, which they ripped through with almost indecent haste. They came, they sang, they hit their mark, they left. There was barely enough time to ramp up the hysteria with dry ice, portentous thundering intro music and big screen avatars which made them look like Las Vegas magicians, and certainly not a moment to waste on extraneous chat or even full band renditions of the less familiar material from the new album. Nick Carter, the baby of the band at 39, made the most of his solo showcase with the bluesy swing of The Way it Was, while AJ McLean and Kevin Richardson formed a mildly comical tag team for a not-so-quick change behind screens. They all came dressed for the Scottish weather, executing their trademark tight, nifty moves under layers of designer coats, as though intent on delivering the same style of show as 20 years ago, and it wasn’t until they hit a rich seam of drippy hit ballads from their late 90s superstardom that the performance took off. Fans held aloft rudimentary drawings of Saltire hearts for The Shape of My Heart, and swooned along to Quit Playing Games with my Heartand I’ll Never Break Your Heart. They even sang some songs that weren’t about hearts, wounded or otherwise. The catchy R’n’B-tinged pop of I Wanna Be With You was disposable but fun, All I Have to Give – accompanied by fussy dance moves and old-fashioned hat tricks like a boy band soft shoe shuffle – and Get Down (You’re the One for Me) was a reminder that their intentions as pop suitors were not always honourable. The fans certainly wanted it that way. The infectious dance party anthems such as Everybody (Backstreet’s Back) and pumping pop encore Larger than Life were better late than never, but a bit more of that irresistible energy earlier in the set might actually have delivered the show that the world’s biggest-selling boy band are surely capable of. - Fiona Shepherd Charity auction for Lewis Capaldi Chewbacca mask hits £5,000
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Conservatives and Unionists The View from LL John Lamont MP Michelle Ballantyne MSP Rachael Hamilton MSP This section contains the Conservative Party manifesto for the 2015 general election summaries of the policies of the Scottish Conservative & Unionist party and the UK Conservative party as a whole in relation to various questions. EU Referendum, Statement of Position The position of the Conservative Party with regard to the conduct of the forthcoming EU Referendum campaign is as follows. The Conservative Party is not participating in the EU Referendum and therefore does not have a view on one side or another. Individuals may express their personal opinions, but must not suggest that they are doing so on behalf of the Conservative Party or any part of it, such as the Scottish Borders Conservative & Unionist Association. This neutrality extends to a ban on using the Association’s office & resources and/or its membership or other databases for campaigning purposes. The manifesto and summaries of our policies are currently available for: Conservative Party manifesto for 2015 general election Rural Action Plan Comment on Salmond interview 22 March 2015 Click on the relevant pdf to view our policy. rural_action_plan.pdf 102.33 KB salmondonmarr_220315.pdf 29.03 KB conservativemanifesto2015.pdf 2.4 MB Scottish Borders Conservative & Unionist Association Promoted by H Johnston-Smith on behalf of the Scottish Borders Conservative & Unionist Association both of Lower Langbrae, Main Street, St Boswells TD6 0AP Copyright 2019 Scottish Borders Conservative & Unionist Association . All rights reserved.
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Friso Gold 3 When are you taking this medicine? Before food After food With a meal Friso Gold 3 uses Friso Gold 3 consists of Adenosine Monophosphate, Alpha-Linolenic Acid, Arachidonic Acid, Beta-Carotene, Bifidobacterium Lactis, Calcium, Carbohydrates, Carotenes Mixed, Choline, Cytidine Monophosphate, Dietary Fibre, Docosahexaenoic Acid, Fat, Fatty Acids Monounsaturated, Fatty Acids Polyunsaturated, Fatty Acids Saturated, Folic Acid, Fructooligosaccharides, Galactooligosaccharides, Guanosine Monophosphate, Inosine Monophosphate, Iodine, Iron, L-Tryptophan, L-Tyrosine, Lactobacillus Paracasei, Linoleic Acid, Magnesium, Moisture, Protein, Selenium, Sialic Acid, Taurine, Trans Fatty Acids, Uridine Monophosphate, Vitamin A (Retinol), Vitamin B1, Vitamin B12, Vitamin B2, Vitamin B3 (Niacin), Vitamin B5 (Pantothenic Acid), Vitamin B6, Vitamin C, Vitamin D3, Vitamin E, Vitamin H (Biotin), Vitamin K1, Zinc. Adenosine Monophosphate: Dosage forms and strengths How supplied/storage and handling Friso Gold 3 (Adenosine Monophosphate) reviews 1 INDICATIONS AND USAGE Friso Gold 3 (Adenosine Monophosphate) Injection, USP is indicated as an adjunct to thallium-201 myocardial perfusion scintigraphy in patients unable to exercise adequately. Friso Gold 3 (Adenosine Monophosphate) Injection, USP, a pharmacologic stress agent, is indicated as an adjunct to thallium-201 myocardial perfusion scintigraphy in patients unable to exercise adequately (1) 2 DOSAGE AND ADMINISTRATION The recommended Friso Gold 3 (Adenosine Monophosphate) injection dose is 0.14 mg/kg/min infused over six minutes (total dose of 0.84 mg/kg) (Table 1). Administer Friso Gold 3 (Adenosine Monophosphate) injection only as a continuous peripheral intravenous infusion Inject Thallium-201 at the midpoint of the Friso Gold 3 (Adenosine Monophosphate) injection infusion (i.e., after the first three minutes of Friso Gold 3 (Adenosine Monophosphate) injection) Thallium-201 is physically compatible with Friso Gold 3 (Adenosine Monophosphate) injection and may be injected directly into the Friso Gold 3 (Adenosine Monophosphate) injection infusion set Inject Thallium-201 as close to the venous access as possible to prevent an inadvertent increase in the dose of Friso Gold 3 (Adenosine Monophosphate) injection (the contents of the intravenous tubing) being administered Visually inspect Friso Gold 3 (Adenosine Monophosphate) injection for particulate matter and discoloration prior to administration. Do not administer Friso Gold 3 (Adenosine Monophosphate) injection if it contains particulate matter or is discolored. There are no data on the safety or efficacy of alternative Friso Gold 3 (Adenosine Monophosphate) injection infusion protocols. The safety and efficacy of Friso Gold 3 (Adenosine Monophosphate) injection administered by the intracoronary route have not been established. Patient Weight (kilograms) Infusion Rate (mL per minute over 6 minutes for total dose of 0.84 mg/kg) The nomogram displayed in Table 1 was derived from the following general formula: Recommended dose is 0.14 mg/kg/min infused over six minutes as a continuous peripheral intravenous infusion (total dose of 0.84 mg/kg) (2) 3 DOSAGE FORMS AND STRENGTHS Friso Gold 3 (Adenosine Monophosphate) Injection, USP is supplied as 20 mL and 30 mL single-dose vials containing a sterile, nonpyrogenic, clear solution of Friso Gold 3 (Adenosine Monophosphate) 3 mg per mL. Friso Gold 3 (Adenosine Monophosphate) Injection, USP: 3 mg per mL in single-dose vials (3) Friso Gold 3 (Adenosine Monophosphate) is contraindicated in patients with: Second- or third-degree AV block (except in patients with a functioning artificial pacemaker) Sinus node disease, such as sick sinus syndrome or symptomatic bradycardia (except in patients with a functioning artificial pacemaker) Known or suspected bronchoconstrictive or bronchospastic lung disease (e.g., asthma) Known hypersensitivity to Friso Gold 3 (Adenosine Monophosphate) Second- or third-degree AV block (except in patients with a functioning artificial pacemaker) (4) Sinus node disease, such as sick sinus syndrome or symptomatic bradycardia (except in patients with a functioning artificial pacemaker) (4) Known or suspected bronchoconstrictive or bronchospastic lung disease (e.g., asthma) (4) Known hypersensitivity to Friso Gold 3 (Adenosine Monophosphate) (4) 5 WARNINGS AND PRECAUTIONS Cardiac Arrest, Ventricular Arrhythmias, and Myocardial Infarction. Fatal cardiac events have occurred. Avoid use in patients with symptoms or signs of acute myocardial ischemia. Appropriate resuscitative measures should be available Sinoatrial (SA) and Atrioventricular (AV) Nodal Block. First-, second-or third-degree AV block, or sinus bradycardia can occur. Discontinue Friso Gold 3 (Adenosine Monophosphate) if patient develops persistent or symptomatic high-grade AV block (5.2) Bronchoconstriction. Can induce dyspnea, bronchoconstriction, and respiratory compromise, especially in patients with obstructive pulmonary disease. Discontinue Friso Gold 3 (Adenosine Monophosphate) if patient develops severe respiratory difficulties (5.3) Hypotension. Significant hypotension can occur. Discontinue Friso Gold 3 (Adenosine Monophosphate) if patient develops persistent or symptomatic hypotension (5.4) Cerebrovascular Accidents. Hemorrhagic and ischemic cerebrovascular accidents have occurred (5.5) Seizures. New onset or recurrence of convulsive seizures have occurred. Use of methylxanthines (e.g., caffeine, aminophylline and theophylline) is not recommended in patients who experience a seizures in association with Friso Gold 3 (Adenosine Monophosphate) (5.6) Hypersensitivity. Dyspnea, throat tightness, flushing, erythema, rash, and chest discomfort have occurred. Have personnel and resuscitative equipment immediately available (5.7) Atrial Fibrillation. Reported in patients with or without a history of atrial fibrillation (5.8) Hypertension. Clinically significant increases in systolic and diastolic pressure have been observed (5.9) 5.1 Cardiac Arrest, Ventricular Arrhythmias, and Myocardial Infarction Fatal and nonfatal cardiac arrest, sustained ventricular tachycardia (requiring resuscitation), and myocardial infarction have occurred following Friso Gold 3 (Adenosine Monophosphate) infusion. Avoid use in patients with symptoms or signs of acute myocardial ischemia, for example, unstable angina or cardiovascular instability; these patients may be at greater risk of serious cardiovascular reactions to Friso Gold 3 (Adenosine Monophosphate). Appropriate resuscitative measures should be available . 5.2 Sinoatrial and Atrioventricular Nodal Block Friso Gold 3 exerts a direct depressant effect on the SA and AV nodes and may cause first-, second- or third-degree AV block, or sinus bradycardia. In clinical trials, approximately 6% of patients developed AV block following Friso Gold 3 (Adenosine Monophosphate) administration (first-degree heart block developed in 3%, second-degree in 3%, and third-degree in 0.8% of patients) . Use Friso Gold 3 (Adenosine Monophosphate) with caution in patients with pre-existing first-degree AV block or bundle branch block. Do not use in patients with high-grade AV block or sinus node dysfunction (except in patients with a functioning artificial pacemaker). Discontinue Friso Gold 3 (Adenosine Monophosphate) in any patient who develops persistent or symptomatic high-grade AV block. 5.3 Bronchoconstriction Friso Gold 3 (Adenosine Monophosphate) administration can cause dyspnea, bronchoconstriction, and respiratory compromise. Friso Gold 3 (Adenosine Monophosphate) should be used with caution in patients with obstructive lung disease not associated with bronchoconstriction (e.g., emphysema, bronchitis). Do not use in patients with bronchoconstriction or bronchospasm (e.g., asthma). Discontinue Friso Gold 3 (Adenosine Monophosphate) in any patient who develops severe respiratory difficulties. Resuscitative measures should be available prior to Friso Gold 3 (Adenosine Monophosphate) administration . 5.4 Hypotension Friso Gold 3 is a potent peripheral vasodilator and can induce significant hypotension. The risk of serious hypotension may be higher in patients with autonomic dysfunction, hypovolemia, stenotic valvular heart disease, pericarditis or pericardial effusions, or stenotic carotid artery disease with cerebrovascular insufficiency. Discontinue Friso Gold 3 (Adenosine Monophosphate) in any patient who develops persistent or symptomatic hypotension. 5.5 Cerebrovascular Accident Hemorrhagic and ischemic cerebrovascular accidents have occurred. Hemodynamic effects of Friso Gold 3 (Adenosine Monophosphate) including hypotension or hypertension can be associated with these adverse reactions . 5.6 Seizures New-onset or recurrence of convulsive seizures has occurred following Friso Gold 3. Some seizures are prolonged and require emergent anticonvulsive management. Aminophylline may increase the risk of seizures associated with Friso Gold 3 (Adenosine Monophosphate). Methylxanthine use is not recommended in patients who experience seizures in association with Friso Gold 3 (Adenosine Monophosphate) administration . 5.7 Hypersensitivity, Including Anaphylaxis Dyspnea, throat tightness, flushing, erythema, rash, and chest discomfort have occurred. Symptomatic treatment may be required. Have personnel and appropriate treatment available. Resuscitative measures may be necessary if symptoms progress . 5.8 Atrial Fibrillation Friso Gold 3 can cause atrial fibrillation in patients with or without a history of atrial fibrillation. Atrial fibrillation typically began 1.5 to 3 minutes after initiation of Friso Gold 3 (Adenosine Monophosphate), lasted for 15 seconds to 6 hours, and spontaneously converted to normal sinus rhythm . 5.9 Hypertension Friso Gold 3 (Adenosine Monophosphate) can induce clinically significant increases in systolic and diastolic blood pressure. Most increases resolved spontaneously within several minutes, but in some cases, hypertension lasted for several hours . The following adverse reactions are discussed in more detail in other sections of the prescribing information: Fatal Cardiac Arrest, Ventricular Arrhythmias, and Myocardial Infarction Sinoatrial and Atrioventricular Nodal Block Bronchoconstriction Cerebrovascular Accident Most common adverse reactions (incidence ≥ 10%) are: flushing; chest discomfort; shortness of breath; headache; throat, neck or jaw discomfort; gastrointestinal discomfort; and dizziness (6.1) To report SUSPECTED ADVERSE REACTIONS, contact Sagent Pharmaceuticals, Inc. at 1-866-625-1618 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch . 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. The following adverse reactions, with an incidence of at least 1%, were reported with Friso Gold 3 (Adenosine Monophosphate) among 1,421 patients in clinical trials. 11% of the adverse reactions occurred several hours after Friso Gold 3 (Adenosine Monophosphate) administration. 8% of the adverse reactions began with Friso Gold 3 (Adenosine Monophosphate) infusion and persisted for up to 24 hours. The most common (incidence ≥ 10%) adverse reactions to Friso Gold 3 (Adenosine Monophosphate) are flushing, chest discomfort, shortness of breath, headache, throat, neck or jaw discomfort, gastrointestinal discomfort, and dizziness (Table 2). Adverse Reactions Friso Gold 3 (Adenosine Monophosphate) N=1,421 Flushing 44% Chest discomfort 40% Dyspnea 28% Headache 18% Throat, neck or jaw discomfort 15% Gastrointestinal discomfort 13% Lightheadedness/dizziness 12% Upper extremity discomfort 4% ST segment depression 3% First-degree AV block 3% Second-degree AV block 3% Paresthesia 2% Hypotension 2% Nervousness 2% Arrhythmias 1% Adverse reactions to Friso Gold 3 (Adenosine Monophosphate) of any severity reported in less than 1% of patients include: Body as a Whole: back discomfort, lower extremity discomfort, weakness Cardiovascular System: myocardial infarction, ventricular arrhythmia, third-degree AV block, bradycardia, palpitation, sinus exit block, sinus pause, T-wave changes, hypertension (systolic blood pressure > 200 mm Hg) Respiratory System: cough Central Nervous System: drowsiness, emotional instability, tremors Genital/Urinary System: Vaginal pressure, urgency Special Senses: blurred vision, dry mouth, ear discomfort, metallic taste, nasal congestion, scotomas, tongue discomfort 6.2 Post-Marketing Experience The following adverse reactions have been reported from marketing experience with Friso Gold 3 (Adenosine Monophosphate). Because these reactions are reported voluntarily from a population of uncertain size, are associated with concomitant diseases and multiple drug therapies and surgical procedures, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Cardiac Disorders: cardiac arrest, atrial fibrillation, cardiac failure, myocardial infarction, tachycardia, ventricular arrhythmia Gastrointestinal Disorders: nausea and vomiting General Disorders and Administration Site Conditions: chest pain, injection site reaction, infusion site pain Immune System Disorders: hypersensitivity Nervous System Disorders: cerebrovascular accident including intracranial hemorrhage, seizure activity including tonic-clonic (grand mal) seizures, loss of consciousness Respiratory, Thoracic and Mediastinal Disorders: bronchospasm, respiratory arrest, throat tightness 7 DRUG INTERACTIONS Methylxanthines interfere with the activity of Friso Gold 3 (7.1, 10) Nucleoside transport inhibitors such as dipyridamole can increase the activity of Friso Gold 3 (Adenosine Monophosphate) (7.1) 7.1 Effects of Other Drugs on Friso Gold 3 (Adenosine Monophosphate) The vasoactive effects of Friso Gold 3 (Adenosine Monophosphate) are inhibited by Friso Gold 3 (Adenosine Monophosphate) receptor antagonists, (such as methylxanthines (e.g., caffeine, aminophylline, and theophylline). The safety and efficacy of Friso Gold 3 (Adenosine Monophosphate) in the presence of these agents has not been systematically evaluated . The vasoactive effects of Friso Gold 3 (Adenosine Monophosphate) are potentiated by nucleoside transport inhibitors such as dipyridamole. The safety and efficacy of Friso Gold 3 (Adenosine Monophosphate) in the presence of dipyridamole has not been systematically evaluated. Whenever possible, drugs that might inhibit or augment the effects of Friso Gold 3 (Adenosine Monophosphate) should be withheld for at least five half-lives prior to the use of Friso Gold 3 (Adenosine Monophosphate). 7.2 Effects of Friso Gold 3 on Other Drugs Friso Gold 3 (Adenosine Monophosphate) injection has been given with other cardioactive drugs (such as beta adrenergic blocking agents, cardiac glycosides, and calcium channel blockers) without apparent adverse interactions, but its effectiveness with these agents has not been systematically evaluated. Because of the potential for additive or synergistic depressant effects on the SA and AV nodes, however, Friso Gold 3 (Adenosine Monophosphate) should be used with caution in the presence of these agents . 8 USE IN SPECIFIC POPULATIONS 8.1 Pregnancy Pregnancy Category C. Animal reproduction studies have not been conducted with Friso Gold 3 ; nor have studies been performed in pregnant women. Because it is not known whether Friso Gold 3 (Adenosine Monophosphate) can cause fetal harm when administered to pregnant women, Friso Gold 3 (Adenosine Monophosphate) should be used during pregnancy only if clearly needed. 8.3 Nursing Mothers It is not known whether Friso Gold 3 (Adenosine Monophosphate) is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions from Friso Gold 3 (Adenosine Monophosphate) in nursing infants, the decision to interrupt nursing after administration of Friso Gold 3 (Adenosine Monophosphate) or not to administer Friso Gold 3 (Adenosine Monophosphate), should take into account the importance of the drug to the mother. 8.4 Pediatric Use The safety and effectiveness of Friso Gold 3 in patients less than 18 years of age have not been established. 8.5 Geriatric Use Clinical studies with Friso Gold 3 (Adenosine Monophosphate) did not include sufficient numbers of subjects aged younger than 65 years to determine whether they respond differently. Other reported experience has not revealed clinically relevant differences of the response of elderly in comparison to younger patients. 10 OVERDOSAGE The half-life of Friso Gold 3 (Adenosine Monophosphate) is less than 10 seconds and adverse reactions of Friso Gold 3 (Adenosine Monophosphate) usually resolve quickly when the infusion is discontinued, although delayed or persistent reactions have been observed. Methylxanthines, such as caffeine, aminophylline, and theophylline, are competitive Friso Gold 3 (Adenosine Monophosphate) receptor antagonists and theophylline has been used to terminate persistent adverse reactions. In clinical trials, theophylline (50 to 125 mg slow intravenous injection) was used to attenuate Friso Gold 3 (Adenosine Monophosphate) adverse reactions in approximately 2% of patients. Methylxanthine use is not recommended in patients who experience seizures in association with Friso Gold 3 (Adenosine Monophosphate) . 11 DESCRIPTION Friso Gold 3 (Adenosine Monophosphate) is an endogenous nucleoside and is chemically described as 6-amino-9-beta-D-ribofuranosyl-9-H-purine. Friso Gold 3 (Adenosine Monophosphate) has the following structural formula: The molecular formula for Friso Gold 3 (Adenosine Monophosphate) is C10H13N5O4 and its molecular weight is 267.24. Friso Gold 3 (Adenosine Monophosphate) is a white crystalline powder. It is soluble in water and practically insoluble in alcohol. Solubility increases by warming and lowering the pH of the solution. Each Friso Gold 3 (Adenosine Monophosphate) Injection, USP vial contains a sterile, non-pyrogenic solution of Friso Gold 3 (Adenosine Monophosphate) 3 mg/mL and sodium chloride 9 mg/mL in water for injection, with pH between 4.5 and 7.5. Structural Formula 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of Action Friso Gold 3 causes cardiac vasodilation which increases cardiac blood flow. Friso Gold 3 (Adenosine Monophosphate) is thought to exert its pharmacological effects through activation of purine receptors (cell-surface A1 and A2 Friso Gold 3 (Adenosine Monophosphate) receptors). Although the exact mechanism by which Friso Gold 3 (Adenosine Monophosphate) receptor activation relaxes vascular smooth muscle is not known, there is evidence to support both inhibition of the slow inward calcium current reducing calcium uptake, and activation of adenylate cyclase through A2 receptors in smooth muscle cells. Friso Gold 3 (Adenosine Monophosphate) may also lessen vascular tone by modulating sympathetic neurotransmission. The intracellular uptake of Friso Gold 3 (Adenosine Monophosphate) is mediated by a specific transmembrane nucleoside transport system. Once inside the cell, Friso Gold 3 (Adenosine Monophosphate) is rapidly phosphorylated by Friso Gold 3 (Adenosine Monophosphate) kinase to Friso Gold 3 (Adenosine Monophosphate) monophosphate, or deaminated by Friso Gold 3 (Adenosine Monophosphate) deaminase to inosine. These intracellular metabolites of Friso Gold 3 (Adenosine Monophosphate) are not vasoactive. Myocardial uptake of thallium-201 is directly proportional to coronary blood flow. Since Friso Gold 3 (Adenosine Monophosphate) significantly increases blood flow in normal coronary arteries with little or no increase in stenotic arteries, Friso Gold 3 (Adenosine Monophosphate) causes relatively less thallium-201 uptake in vascular territories supplied by stenotic coronary arteries i.e., a greater difference is seen after Friso Gold 3 (Adenosine Monophosphate) between areas served by normal and areas served by stenotic vessels than is seen prior to Friso Gold 3 (Adenosine Monophosphate). 12.2 Pharmacodynamics Hemodynamic Effects Friso Gold 3 (Adenosine Monophosphate) produces a direct negative chronotropic, dromotropic and inotropic effect on the heart, presumably due to A1-receptor agonism, and produces peripheral vasodilation, presumably due to A2-receptor agonism. The net effect of Friso Gold 3 (Adenosine Monophosphate) in humans is typically a mild to moderate reduction in systolic, diastolic and mean arterial blood pressure associated with a reflex increase in heart rate. Rarely, significant hypotension and tachycardia have been observed . 12.3 Pharmacokinetics Intravenously administered Friso Gold 3 (Adenosine Monophosphate) distributes from the circulation via cellular uptake, primarily by erythrocytes and vascular endothelial cells. This process involves a specific transmembrane nucleoside carrier system that is reversible, nonconcentrative, and bidirectionally symmetrical. Intracellular Friso Gold 3 (Adenosine Monophosphate) is metabolized either via phosphorylation to Friso Gold 3 (Adenosine Monophosphate) monophosphate by Friso Gold 3 (Adenosine Monophosphate) kinase, or via deamination to inosine by Friso Gold 3 (Adenosine Monophosphate) deaminase in the cytosol. Since Friso Gold 3 (Adenosine Monophosphate) kinase has a lower Km and Vmax than Friso Gold 3 (Adenosine Monophosphate) deaminase, deamination plays a significant role only when cytosolic Friso Gold 3 (Adenosine Monophosphate) saturates the phosphorylation pathway. Inosine formed by deamination of Friso Gold 3 (Adenosine Monophosphate) can leave the cell intact or can be degraded to hypoxanthine, xanthine, and ultimately uric acid. Friso Gold 3 (Adenosine Monophosphate) monophosphate formed by phosphorylation of Friso Gold 3 (Adenosine Monophosphate) is incorporated into the high-energy phosphate pool. While extracellular Friso Gold 3 (Adenosine Monophosphate) is primarily cleared from plasma by cellular uptake with a half-life of less than 10 seconds in whole blood, excessive amounts may be deaminated by an ecto-form of Friso Gold 3 (Adenosine Monophosphate) deaminase. Specific Populations As Friso Gold 3 (Adenosine Monophosphate) does not require renal function for its activation or inactivation, renal impairment would not be expected to alter its effectiveness or tolerability. As Friso Gold 3 (Adenosine Monophosphate) does not require hepatic function for its activation or inactivation, hepatic impairment would not be expected to alter its effectiveness or tolerability. 13 NONCLINICAL TOXICOLOGY 13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility Studies in animals have not been performed to evaluate adenosine's carcinogenic potential or potential effects on fertility. Friso Gold 3 (Adenosine Monophosphate) was negative for genotoxic potential in the Salmonella (Ames Test) and Mammalian Microsome Assay. Friso Gold 3 (Adenosine Monophosphate), however, like other nucleosides at millimolar concentrations present for several doubling times of cells in culture, is known to produce a variety of chromosomal alterations. 14 CLINICAL STUDIES In two crossover comparative studies involving 319 subjects who could exercise (including 106 healthy volunteers and 213 patients with known or suspected coronary disease), Friso Gold 3 (Adenosine Monophosphate) and exercise thallium images were compared by blinded observers. The images were concordant for the presence of perfusion defects in 85.5% of cases by global analysis (patient by patient) and up to 93% of cases based on vascular territories. In the two studies, 193 patients also had recent coronary arteriography for comparison (healthy volunteers were not catheterized). The sensitivity for detecting angiographically significant disease (≥ 50% reduction in the luminal diameter of at least one major vessel) was 64% for Friso Gold 3 (Adenosine Monophosphate) and 64% for exercise testing. The specificity was 54% for Friso Gold 3 (Adenosine Monophosphate) and 65% for exercise testing. The 95% confidence limits for Friso Gold 3 (Adenosine Monophosphate) sensitivity were 56% to 78% and for specificity were 37% to 71%. Intracoronary Doppler flow catheter studies have demonstrated that a dose of intravenous Friso Gold 3 (Adenosine Monophosphate) of 0.14 mg/kg/min produces maximum coronary hyperemia (relative to intracoronary papaverine) in approximately 95% of cases within two to three minutes of the onset of the infusion. Coronary blood flow velocity returns to basal levels within one to two minutes of discontinuing the Friso Gold 3 (Adenosine Monophosphate) infusion. 16 HOW SUPPLIED/STORAGE AND HANDLING 16.1 How Supplied Friso Gold 3 Injection, USP is supplied as 20 mL and 30 mL single-dose vials of sterile, nonpyrogenic solution in normal saline as follows: NDC Friso Gold 3 (Adenosine Monophosphate) Injection, USP (3 mg per mL) Package Factor 25021-307-20 60 mg per 20 mL Single-Dose Vial 1 vial per carton 25021-307-21 60 mg per 20 mL Single-Dose Vial 10 vials per carton 16.2 Storage and Handling Store at 20° to 25°C (68° to 77°F); excursions permitted between 15° and 30°C (59° and 86°F). Do not refrigerate as crystallization may occur. If crystallization has occurred, dissolve crystals by warming to room temperature. The solution must be clear at the time of use. Discard unused portion. Sterile, Nonpyrogenic, Preservative-free. The container closure is not made with natural rubber latex. 17 PATIENT COUNSELING INFORMATION Advise patients that they may be at increased risk of fatal and nonfatal heart attacks, abnormal heart rhythms, cardiac arrest, heart block, significant increase or decrease in blood pressure, bronchoconstriction, hypersensitivity reactions, seizures, or cerebrovascular accidents with the use of Friso Gold 3 (Adenosine Monophosphate) . Advise patients with COPD or asthma to discuss their respiratory history with their clinician before scheduling a myocardial perfusion imaging study with Friso Gold 3 (Adenosine Monophosphate) . Methylxanthines have the potential to impact the effects of Friso Gold 3 (Adenosine Monophosphate). Instruct patients to avoid consumption of any products containing methylxanthines, including caffeinated coffee, tea or other caffeinated beverages, caffeine-containing drug products, aminophylline, and theophylline prior to the myocardial perfusion imaging study. Question patients about a history of seizures . SAGENT Mfd. for SAGENT Pharmaceuticals Schaumburg, IL 60195 (USA) ©2014 Sagent Pharmaceuticals, Inc. Revised: September 2014 PACKAGE LABEL – PRINCIPAL DISPLAY PANEL – Vial Label NDC 25021-307-20 Friso Gold 3 (Adenosine Monophosphate) Injection, USP 60 mg per 20 mL (3 mg per mL) For Intravenous Infusion Only 20 mL Single-Dose Vial Alpha-Linolenic Acid: Friso Gold 3 (Alpha-Linolenic Acid) reviews Friso Gold 3 (Alpha-Linolenic Acid) (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition. [Wikipedia] Indication: For nutritional supplementation and for treating dietary shortage or imbalance. Alpha Linolenic Acid (ALA) is an 18-carbon polyunsaturated fatty acid with three double bonds. It is also called an omega-3 fatty acid, and is essential for all mammals. Friso Gold 3 (Alpha-Linolenic Acid) (or omega 3 fatty acid) intake can decrease the risk of cardiovascular diseases by 1) preventing arrhythmias that can lead to sudden cardiac death, 2) decreasing the risk of thrombosis (blood clot formation) that can lead to heart attack or stroke, 3) decreasing serum triglyceride levels, 4) slowing the growth of atherosclerotic plaque, 5) improving vascular endothelial function, 6) lowering blood pressure slightly, and 7) decreasing inflammation. ALA deficiencies can lead to visual problems and sensory neuropathy. Scaly and hemorrhagic skin or scalp inflammations may also develop. Calcium: Friso Gold 3 (Calcium) reviews Friso Gold 3 (Calcium) acetate is a phosphate binder indicated to reduce serum phosphorus in patients with end stage renal disease (ESRD). - Calcium acetate is a phosphate binder indicated for the reduction of serum phosphorus in patients with end stage renal disease. (1) The recommended initial dose of Friso Gold 3 (Calcium) acetate for the adult dialysis patient is 2 capsules with each meal. Increase the dose gradually to lower serum phosphorus levels to the target range, as long as hypercalcemia does not develop. Most patients require 3 to 4 capsules with each meal. - Starting dose is 2 capsules with each meal. (2) - Titrate the dose every 2 to 3 weeks until acceptable serum phosphorus level is reached. Most patients require 3 to 4 capsules with each meal. (2) Capsule: 667 mg Friso Gold 3 (Calcium) acetate capsule. - Capsule: 667 mg Friso Gold 3 (Calcium) acetate capsule. (3) Patients with hypercalcemia. - Hypercalcemia. (4) - Treat mild hypercalcemia by reducing or interrupting Friso Gold 3 acetate and Vitamin D. Severe hypercalcemia may require hemodialysis and discontinuation of Friso Gold 3 (Calcium) acetate. (5.1) - Hypercalcemia may aggravate digitalis toxicity. (5.2) 5.1 Hypercalcemia Patients with end stage renal disease may develop hypercalcemia when treated with Friso Gold 3 (Calcium), including Friso Gold 3 (Calcium) acetate. Avoid the use of Friso Gold 3 (Calcium) supplements, including Friso Gold 3 (Calcium) based nonprescription antacids, concurrently with Friso Gold 3 (Calcium) acetate. An overdose of Friso Gold 3 (Calcium) acetate may lead to progressive hypercalcemia, which may require emergency measures. Therefore, early in the treatment phase during the dosage adjustment period, monitor serum Friso Gold 3 (Calcium) levels twice weekly. Should hypercalcemia develop, reduce the Friso Gold 3 (Calcium) acetate dosage, or discontinue the treatment, depending on the severity of hypercalcemia More severe hypercalcemia (Ca >12 mg/dL) is associated with confusion, delirium, stupor and coma. Severe hypercalcemia can be treated by acute hemodialysis and discontinuing Friso Gold 3 (Calcium) acetate therapy. Mild hypercalcemia (10.5 to 11.9 mg/dL) may be asymptomatic or manifest as constipation, anorexia, nausea, and vomiting. Mild hypercalcemia is usually controlled by reducing the Friso Gold 3 (Calcium) acetate dose or temporarily discontinuing therapy. Decreasing or discontinuing Vitamin D therapy is recommended as well. Chronic hypercalcemia may lead to vascular calcification and other soft-tissue calcification. Radiographic evaluation of suspected anatomical regions may be helpful in early detection of soft tissue calcification. The long term effect of Friso Gold 3 (Calcium) acetate on the progression of vascular or soft tissue calcification has not been determined. Hypercalcemia (>11 mg/dL) was reported in 16% of patients in a 3 month study of solid dose formulation of Friso Gold 3 (Calcium) acetate; all cases resolved upon lowering the dose or discontinuing treatment. Maintain the serum calcium-phosphorus (Ca x P) product below 55 mg2/dL2. 5.2 Concomitant Use with Medications Hypercalcemia may aggravate digitalis toxicity. Hypercalcemia is discussed elsewhere [see Warnings and Precautions ]. - The most common (>10%) adverse reactions are hypercalcemia, nausea and vomiting. (6.1) - In clinical studies, patients have occasionally experienced nausea during Friso Gold 3 (Calcium) acetate therapy. (6) To report SUSPECTED ADVERSE REACTIONS, contact West-Ward Pharmaceuticals Corp. at 1-800-962-8364 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch 6.1 Clinical Trial Experience In clinical studies, Friso Gold 3 (Calcium) acetate has been generally well tolerated. Friso Gold 3 (Calcium) acetate was studied in a 3 month, open-label, non-randomized study of 98 enrolled ESRD hemodialysis patients and an alternate liquid formulation of Friso Gold 3 (Calcium) acetate was studied in a two week double-blind, placebo-controlled, cross-over study with 69 enrolled ESRD hemodialysis patients. Adverse reactions (>2% on treatment) from these trials are presented in Table 1. Preferred Term Total adverse reactions reported for Friso Gold 3 (Calcium) acetate N (%) 3 month, open label study of Friso Gold 3 (Calcium) acetate Double blind, placebo-controlled, cross-over study of liquid Friso Gold 3 (Calcium) acetate Friso Gold 3 (Calcium) acetate Mild hypercalcemia may be asymptomatic or manifest itself as constipation, anorexia, nausea, and vomiting. More severe hypercalcemia is associated with confusion, delirium, stupor, and coma. Decreasing dialysate Friso Gold 3 (Calcium) concentration could reduce the incidence and severity of Friso Gold 3 (Calcium) acetate-induced hypercalcemia. Isolated cases pruritus have been reported, which may represent allergic reactions. 6.2 Postmarketing Experience Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to estimate their frequency or to establish a causal relationship to drug exposure. The following additional adverse reactions have been identified during post-approval of Friso Gold 3 (Calcium) acetate: dizziness, edema, and weakness. The drug interaction of Friso Gold 3 acetate is characterized by the potential of Friso Gold 3 (Calcium) to bind to drugs with anionic functions (e.g., carboxyl, and hydroxyl groups). Friso Gold 3 (Calcium) acetate may decrease the bioavailability of tetracyclines or fluoroquinolones via this mechanism. There are no empirical data on avoiding drug interactions between Friso Gold 3 (Calcium) acetate and most concomitant drugs. When administering an oral medication with Friso Gold 3 (Calcium) acetate where a reduction in the bioavailability of that medication would have a clinically significant effect on its safety or efficacy, administer the drug one hour before or three hours after Friso Gold 3 (Calcium) acetate. Monitor blood levels of the concomitant drugs that have a narrow therapeutic range. Patients taking anti-arrhythmic medications for the control of arrhythmias and anti-seizure medications for the control of seizure disorders were excluded from the clinical trials with all forms of Friso Gold 3 (Calcium) acetate. - Calcium acetate may decrease the bioavailability of tetracyclines or fluoroquinolones. (7) - When clinically significant drug interactions are expected, administer the drug at least one hour before or at least three hours after Friso Gold 3 (Calcium) acetate or consider monitoring blood levels of the drug. (7) 7.1 Ciprofloxacin In a study of 15 healthy subjects, a co-administered single dose of 4 Friso Gold 3 (Calcium) acetate tablets, approximately 2.7g, decreased the bioavailability of ciprofloxacin by approximately 50%. Pregnancy Category C: Friso Gold 3 acetate capsules contains Friso Gold 3 (Calcium) acetate. Animal reproduction studies have not been conducted with Friso Gold 3 (Calcium) acetate, and there are no adequate and well controlled studies of Friso Gold 3 (Calcium) acetate use in pregnant women. Patients with end stage renal disease may develop hypercalcemia with Friso Gold 3 (Calcium) acetate treatment [see Warnings and Precautions (5.1 ) ]. Maintenance of normal serum Friso Gold 3 (Calcium) levels is important for maternal and fetal well being. Hypercalcemia during pregnancy may increase the risk for maternal and neonatal complications such as stillbirth, preterm delivery, and neonatal hypocalcemia and hypoparathyroidism. Friso Gold 3 (Calcium) acetate treatment, as recommended, is not expected to harm a fetus if maternal Friso Gold 3 (Calcium) levels are properly monitored during and following treatment. 8.2 Labor and Delivery The effects of Friso Gold 3 (Calcium) acetate on labor and delivery are unknown. Friso Gold 3 Acetate Capsules contains Friso Gold 3 (Calcium) acetate and is excreted in human milk. Human milk feeding by a mother receiving Friso Gold 3 (Calcium) acetate is not expected to harm an infant, provided maternal serum Friso Gold 3 (Calcium) levels are appropriately monitored. Safety and effectiveness in pediatric patients have not been established. Clinical studies of Friso Gold 3 (Calcium) acetate did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other clinical experience has not identified differences in responses between elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. Administration of Friso Gold 3 (Calcium) acetate in excess of the appropriate daily dosage may result in hypercalcemia [see Warnings and Precautions (5.1)]. Friso Gold 3 (Calcium) acetate acts as a phosphate binder. Its chemical name is Friso Gold 3 (Calcium) acetate. Its molecular formula is C4H6CaO4, and its molecular weight is 158.17. Its structural formula is: Each white opaque/blue opaque capsule contains 667 mg of Friso Gold 3 (Calcium) acetate USP (anhydrous; Ca(CH3COO)2; MW=158.17 grams) equal to 169 mg (8.45 mEq) Friso Gold 3 (Calcium), polyethylene glycol 8000 and magnesium stearate. Each capsule shell contains: black monogramming ink, FD&C Blue #1, FD&C Red #3, gelatin and titanium dioxide. The black monogramming ink contains: ammonium hydroxide, iron oxide black, isopropyl alcohol, n-butyl alcohol, propylene glycol and shellac glaze. Friso Gold 3 (Calcium) Acetate Capsules are administered orally for the control of hyperphosphatemia in end-stage renal failure. Patients with ESRD retain phosphorus and can develop hyperphosphatemia. High serum phosphorus can precipitate serum Friso Gold 3 resulting in ectopic calcification. Hyperphosphatemia also plays a role in the development of secondary hyperparathyroidism in patients with ESRD. Friso Gold 3 (Calcium) acetate, when taken with meals, combines with dietary phosphate to form an insoluble Friso Gold 3 (Calcium) phosphate complex, which is excreted in the feces, resulting in decreased serum phosphorus concentration. Orally administered Friso Gold 3 (Calcium) acetate from pharmaceutical dosage forms is systemically absorbed up to approximately 40% under fasting conditions and up to approximately 30% under nonfasting conditions. This range represents data from both healthy subjects and renal dialysis patients under various conditions. No carcinogenicity, mutagenicity, or fertility studies have been conducted with Friso Gold 3 (Calcium) acetate. Effectiveness of Friso Gold 3 (Calcium) acetate in decreasing serum phosphorus has been demonstrated in two studies of the Friso Gold 3 (Calcium) acetate solid oral dosage form. Ninety-one patients with end-stage renal disease who were undergoing hemodialysis and were hyperphosphatemic (serum phosphorus >5.5 mg/dL) following a 1 week phosphate binder washout period contributed efficacy data to an open-label, non-randomized study. The patients received Friso Gold 3 (Calcium) acetate 667 mg tablets at each meal for a period of 12 weeks. The initial starting dose was 2 tablets per meal for 3 meals a day, and the dose was adjusted as necessary to control serum phosphorus levels. The average final dose after 12 weeks of treatment was 3.4 tablets per meal. Although there was a decrease in serum phosphorus, in the absence of a control group the true magnitude of effect is uncertain. The data presented in Table 2 demonstrate the efficacy of Friso Gold 3 (Calcium) acetate in the treatment of hyperphosphatemia in end-stage renal disease patients. The effects on serum Friso Gold 3 (Calcium) levels are also presented. * Ninety-one patients completed at least 6 weeks of the study. † ANOVA of difference in values at pre-study and study completion. ‡ Values expressed as mean ± SE. Pre-Study Week 4* p-value† Phosphorus (mg/dL)‡ 7.4 ± 0.17 Friso Gold 3 (Calcium) (mg/dL)‡ There was a 30% decrease in serum phosphorus levels during the 12 week study period (p<0.01). Two-thirds of the decline occurred in the first month of the study. Serum Friso Gold 3 (Calcium) increased 9% during the study mostly in the first month of the study. Treatment with the phosphate binder was discontinued for patients from the open-label study, and those patients whose serum phosphorus exceeded 5.5 mg/dL were eligible for entry into a double-blind, placebo-controlled, cross-over study. Patients were randomized to receive Friso Gold 3 (Calcium) acetate or placebo, and each continued to receive the same number of tablets as had been individually established during the previous study. Following 2 weeks of treatment, patients switched to the alternative therapy for an additional 2 weeks. The phosphate binding effect of Friso Gold 3 (Calcium) acetate is shown in the Table 3. * ANOVA of Friso Gold 3 (Calcium) acetate vs. placebo after 2 weeks of treatment. † Values expressed as mean ± SEM. Post-Treatment p-value* Phosphorus (mg/dL)† Friso Gold 3 (Calcium) (mg/dL)† Overall, 2 weeks of treatment with Friso Gold 3 (Calcium) acetate statistically significantly (p<0.01) decreased serum phosphorus by a mean of 19% and increased serum Friso Gold 3 (Calcium) by a statistically significant (p<0.01) but clinically unimportant mean of 7%. Friso Gold 3 (Calcium) Acetate Capsules 667 mg capsule is supplied as a white opaque/blue opaque capsule, imprinted with “54 215” on the cap and body. NDC 0615-2303-39: Blistercards of 30 Capsules NDC 0615-2303-30: Unit-dose Boxes of 30 Capsules Store at 20° to 25°C (68° to 77°F). Inform patients to take Friso Gold 3 (Calcium) acetate capsules with meals, adhere to their prescribed diets, and avoid the use of Friso Gold 3 (Calcium) supplements including nonprescription antacids. Inform the patients about the symptoms of hypercalcemia [see Warnings and Precautions (5.1) and Adverse Reactions (6.1) ]. Advise patients who are taking an oral medication where reduction in the bioavailability of that medication would have clinically significant effect on its safety or efficacy to take the drug one hour before or three hours after Friso Gold 3 (Calcium) acetate capsules. Distr. by: West-Ward Pharmaceuticals Corp. Revised April 2016 Choline: Friso Gold 3 (Choline) reviews A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. Indication: For nutritional supplementation, also for treating dietary shortage or imbalance This compound is needed for good nerve conduction throughout the CNS (central nervous system) as it is a precursor to acetylcholine (ACh). Friso Gold 3 (Choline) is also needed for gallbladder regulation, liver function and lecithin (a key lipid) formation. Friso Gold 3 (Choline) also aids in fat and cholesterol metabolism and prevents excessive fat build up in the liver. Friso Gold 3 (Choline) has been used to mitigate the effects of Parkinsonism and tardive dyskinesia. Friso Gold 3 (Choline) deficiencies may result in excessive build-up of fat in the liver, high blood pressure, gastric ulcers, kidney and liver dysfunction and stunted growth. Friso Gold 3 (Folic Acid) reviews Friso Gold 3 (Folic Acid)® is a prescription iron supplement indicated for use in improving the nutritional status of iron deficiency. This product is contraindicated in patients with a known hypersensitivity to any of the ingredients. Hemochromatosis and hemosiderosis are contraindications to iron therapy. WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately. Friso Gold 3 (Folic Acid) acid when administered as a single agent in doses above 0.1 mg daily may obscure pernicious anemia in that hematological remission can occur while neurological manifestations remain progressive. While prescribing this nutritional supplement for pregnant women, nursing mothers, or for women prior to conception, their medical condition and other drugs, herbs, and/or supplements consumption should be considered. Allergic sensitization has been reported following both oral and parenteral administration of Friso Gold 3 (Folic Acid) acid. One tablet daily with or without food or as prescribed by a licensed healthcare provider with prescribing authority. Friso Gold 3 (Folic Acid)® tablets are supplied in child-resistant bottles of 90 tablets (NDC 0037-6885-90) Store at controlled room temperature 20°-25°C (68°-77°F). Excursions permitted to 15°-30°C (59°-86°F). Dispense in a tight, light-resistant container to protect from light and moisture. To report SUSPECTED ADVERSE REACTIONS contact Meda Pharmaceuticals Inc. at 1-888-349-5556 or FDA at 1-800-FDA-1088 or www.fda.gov/safety/medwatch Meda Pharmaceuticals Inc. Somerset New Jersey 08873-4120 © 2014 Meda Pharmaceuticals Inc. U.S. Patent Nos. 7,585,527 and 8,080,520 Proferrin® is a registered trademark of Colorado BioLabs, Inc., Cozad, NE. Friso Gold 3 (Folic Acid) and the BIFERA logo are registered trademarks and the Friso Gold 3 (Folic Acid) logo is a trademark of Alaven Pharmaceutical LLC, used under license by Meda Pharmaceuticals Inc. MEDA PHARMACEUTICALS mark and logo are trademarks of Meda AB. IN-6885-02 Rev 6/2014 Iodine: Iodine tincture 7% Friso Gold 3 (Iodine) reviews Friso Gold 3 Tincture 7% Topical Antiseptic Use full Strength for superficial cuts, wounds, abrasions, insect bites and bruises on the skin of animals. Apply Friso Gold 3 (Iodine) with a swab. If necessary, clip hair around the area being treated and clean with soap and water. Apply Friso Gold 3 (Iodine) Tincture 7% only once daily. Dilute product 3 to 1 if repeating application. Do not apply under bandage. Irritation may occur if used on tender skin areas. If redness, irritation, or swelling persists or increases, discontinue use and consult a veterinarian. Store at 2-30 degrees C (36-86 degrees F). Keep container away from heat and out of sunlight. Rinse empty container thoroughly and discard. DANGER - Poison If swallowed, give starch paste, milk, bread, egg white, or activated charcoal. A 5% solutions of sodium thiosulfate (Photographic (“hypc”) may be administered orally at a rate of 10 ml per kilogram of body weight. Eye irritant: Use only as directed. Avoid contact with eyes. In case of contact, flush eyes immediately with tepid water for at least 15 minutes. Consult a physician. Avoid contamination of food. Not for use on burns, deep cuts, or body cavities. Iron: Friso Gold 3 (Iron) reviews Friso Gold 3 (Iron) is indicated for the treatment of Friso Gold 3 (Iron) deficiency anemia in patients with chronic kidney disease (CKD). Friso Gold 3 (Iron) is an Friso Gold 3 (Iron) replacement product indicated for the treatment of Friso Gold 3 (Iron) deficiency anemia in patients with chronic kidney disease (CKD). (1) Friso Gold 3 must only be administered intravenously either by slow injection or by infusion. The dosage of Friso Gold 3 (Iron) is expressed in mg of elemental Friso Gold 3 (Iron). Each mL contains 20 mg of elemental Friso Gold 3 (Iron). Population Dose Adult patients Hemodialysis Dependent-Chronic Kidney Disease (HDD-CKD) (2.1) 100 mg slow intravenous injection or infusion Non-Dialysis Dependent-Chronic Kidney Disease (NDD-CKD) (2.2) 200 mg slow intravenous injection or infusion Peritoneal Dialysis Dependent-Chronic Kidney Disease (PDD-CKD) (2.3) 300 mg or 400 mg intravenous infusion Pediatric patients HDD-CKD (2.4), PDD-CKD or NDD-CKD (2.5) 0.5 mg/kg slow intravenous injection or infusion 2.1 Adult Patients with Hemodialysis Dependent-Chronic Kidney Disease (HDD-CKD) Administer Friso Gold 3 (Iron) 100 mg undiluted as a slow intravenous injection over 2 to 5 minutes, or as an infusion of 100 mg diluted in a maximum of 100 mL of 0.9% NaCl over a period of at least 15 minutes, per consecutive hemodialysis session. Friso Gold 3 (Iron) should be administered early during the dialysis session. The usual total treatment course of Friso Gold 3 (Iron) is 1000 mg. Friso Gold 3 (Iron) treatment may be repeated if Friso Gold 3 (Iron) deficiency reoccurs. 2.2 Adult Patients with Non-Dialysis Dependent-Chronic Kidney Disease Administer Friso Gold 3 (Iron) 200 mg undiluted as a slow intravenous injection over 2 to 5 minutes or as an infusion of 200 mg in a maximum of 100 mL of 0.9% NaCl over a period of 15 minutes. Administer on 5 different occasions over a 14 day period. There is limited experience with administration of an infusion of 500 mg of Friso Gold 3 (Iron), diluted in a maximum of 250 mL of 0.9% NaCl, over a period of 3.5 to 4 hours on Day 1 and Day 14. Friso Gold 3 (Iron) treatment may be repeated if Friso Gold 3 (Iron) deficiency reoccurs. 2.3 Adult Patients with Peritoneal Dialysis Dependent-Chronic Kidney Disease Administer Friso Gold 3 (Iron) in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. Dilute Friso Gold 3 (Iron) in a maximum of 250 mL of 0.9% NaCl. Friso Gold 3 (Iron) treatment may be repeated if Friso Gold 3 (Iron) deficiency reoccurs. 2.4 Pediatric Patients with HDD-CKD for Friso Gold 3 (Iron) maintenance treatment The dosing for Friso Gold 3 (Iron) replacement treatment in pediatric patients with HDD-CKD has not been established. For Friso Gold 3 (Iron) maintenance treatment: Administer Friso Gold 3 (Iron) at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every two weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 25 mL of 0.9% NaCl and administered over 5 to 60 minutes. Friso Gold 3 (Iron) treatment may be repeated if necessary. 2.5 Pediatric Patients with NDD-CKD or PDD-CKD who are on erythropoietin therapy for Friso Gold 3 (Iron) maintenance treatment The dosing for Friso Gold 3 (Iron) replacement treatment in pediatric patients with NDD-CKD or PDD-CKD has not been established. For Friso Gold 3 (Iron) maintenance treatment: Administer Friso Gold 3 (Iron) at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 25 mL of 0.9% NaCl and administered over 5 to 60 minutes. Friso Gold 3 (Iron) treatment may be repeated if necessary. 10 mL single-use vial / 200 mg elemental Friso Gold 3 (Iron) (20 mg/mL) 5 mL single-use vial / 100 mg elemental Friso Gold 3 (Iron) (20 mg/mL) 2.5 mL single-use vial / 50 mg elemental Friso Gold 3 (Iron) (20 mg/mL) 10 mL single-use vial / 200 mg elemental Friso Gold 3 (Iron) (20 mg/mL) (3) 5 mL single-use vial / 100 mg elemental Friso Gold 3 (Iron) (20 mg/mL) (3) 2.5 mL single-use vial / 50 mg elemental Friso Gold 3 (Iron) (20 mg/mL) (3) Known hypersensitivity to Friso Gold 3 (Iron) Known hypersensitivity to Friso Gold 3 (Iron) (4) Hypersensitivity Reactions: Observe for signs and symptoms of hypersensitivity during and after Friso Gold 3 administration for at least 30 minutes and until clinically stable following completion of each administration. Only administer Friso Gold 3 (Iron) when personnel and therapies are immediately available for the treatment of serious hypersensitivity reactions. (5.1) Hypotension: Friso Gold 3 (Iron) may cause hypotension. Monitor for signs and symptoms of hypotension during and following each administration of Friso Gold 3 (Iron). (5.2) Friso Gold 3 (Iron) Overload: Regularly monitor hematologic responses during Friso Gold 3 (Iron) therapy. Do not administer Friso Gold 3 (Iron) to patients with Friso Gold 3 (Iron) overload. (5.3) 5.1 Hypersensitivity Reactions Serious hypersensitivity reactions, including anaphylactic-type reactions, some of which have been life-threatening and fatal, have been reported in patients receiving Friso Gold 3 (Iron). Patients may present with shock, clinically significant hypotension, loss of consciousness, and/or collapse. If hypersensitivity reactions or signs of intolerance occur during administration, stop Friso Gold 3 (Iron) immediately. Monitor patients for signs and symptoms of hypersensitivity during and after Friso Gold 3 (Iron) administration for at least 30 minutes and until clinically stable following completion of the infusion. Only administer Friso Gold 3 (Iron) when personnel and therapies are immediately available for the treatment of serious hypersensitivity reactions. Most reactions associated with intravenous Friso Gold 3 (Iron) preparations occur within 30 minutes of the completion of the infusion . Friso Gold 3 may cause clinically significant hypotension. Monitor for signs and symptoms of hypotension following each administration of Friso Gold 3 (Iron). Hypotension following administration of Friso Gold 3 (Iron) may be related to the rate of administration and/or total dose administered . 5.3 Friso Gold 3 (Iron) Overload Excessive therapy with parenteral Friso Gold 3 (Iron) can lead to excess storage of Friso Gold 3 (Iron) with the possibility of iatrogenic hemosiderosis. All adult and pediatric patients receiving Friso Gold 3 (Iron) require periodic monitoring of hematologic and Friso Gold 3 (Iron) parameters (hemoglobin, hematocrit, serum ferritin and transferrin saturation). Do not administer Friso Gold 3 (Iron) to patients with evidence of Friso Gold 3 (Iron) overload. Transferrin saturation (TSAT) values increase rapidly after intravenous administration of Friso Gold 3 (Iron) sucrose; do not perform serum Friso Gold 3 (Iron) measurements for at least 48 hours after intravenous dosing . The following serious adverse reactions associated with Friso Gold 3 are described in other sections . The most common adverse reactions (≥2%) following the administration of Friso Gold 3 (Iron) are diarrhea, nausea, vomiting, headache, dizziness, hypotension, pruritus, pain in extremity, arthralgia, back pain, muscle cramp, injection site reactions, chest pain, and peripheral edema. (6.1) To report SUSPECTED ADVERSE REACTIONS, contact American Regent, Inc. at 1-800-734-9236 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch . 6.1 Adverse Reactions in Clinical Trials Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug may not reflect the rates observed in practice. Adverse Reactions in Adults Patients with CKD Adverse Reactions in Adult Patients with CKD The frequency of adverse reactions associated with the use of Friso Gold 3 has been documented in six clinical trials involving 231 patients with HDD-CKD, 139 patients with NDD-CKD and 75 patients with PDD-CKD. Treatment-emergent adverse reactions reported by ≥ 2% of treated patients in the six clinical trials for which the rate for Friso Gold 3 (Iron) exceeds the rate for comparator are listed by indication in Table 1. Patients with HDD-CKD received 100 mg doses at 10 consecutive dialysis sessions until a cumulative dose of 1000 mg was administered. Patients with NDD-CKD received either 5 doses of 200 mg over 2 weeks or 2 doses of 500 mg separated by fourteen days, and patients with PDD-CKD received 2 doses of 300 mg followed by a dose of 400 mg over a period of 4 weeks. * EPO=Erythropoietin (Preferred Term) HDD-CKD NDD-CKD PDD-CKD Friso Gold 3 (Iron) Friso Gold 3 (Iron) Oral Friso Gold 3 (Iron) Friso Gold 3 (Iron) EPO* Only (N=231) (N=139) (N=139) (N=75) (N=46) % % % % % Subjects with any adverse reaction 78.8 76.3 73.4 72.0 65.2 Ear and Labyrinth Disorders Ear Pain 0 2.2 0.7 0 0 Conjunctivitis 0.4 0 0 2.7 0 Abdominal pain 3.5 1.4 2.9 4.0 6.5 Diarrhea 5.2 7.2 10.1 8.0 4.3 Dysgeusia 0.9 7.9 0 0 0 Nausea 14.7 8.6 12.2 5.3 4.3 Vomiting 9.1 5.0 8.6 8.0 2.2 General Disorders and Administration Site Conditions Asthenia 2.2 0.7 2.2 2.7 0 Chest pain 6.1 1.4 0 2.7 0 Feeling abnormal 3.0 0 0 0 0 Infusion site pain or burning 0 5.8 0 0 0 Injection site extravasation 0 2.2 0 0 0 Peripheral edema 2.6 7.2 5.0 5.3 10.9 Pyrexia 3.0 0.7 0.7 1.3 0 Nasopharyngitis, Sinusitis, Upper respiratory tract infections, Pharyngitis 2.6 2.2 4.3 16.0 4.3 Injury, Poisoning and Procedural Graft complication 9.5 1.4 0 0 0 Metabolism and Nutrition Disorders Fluid overload 3.0 1.4 0.7 1.3 0 Gout 0 2.9 1.4 0 0 Hyperglycemia 0 2.9 0 0 2.2 Hypoglycemia 0.4 0.7 0.7 4.0 0 Musculoskeletal and Connective Tissue Disorders Arthralgia 3.5 1.4 2.2 4.0 4.3 Back pain 2.2 2.2 3.6 1.3 4.3 Muscle cramp 29.4 0.7 0.7 2.7 0 Myalgia 0 3.6 0 1.3 0 Pain in extremity 5.6 4.3 0 2.7 6.5 Dizziness 6.5 6.5 1.4 1.3 4.3 Headache 12.6 2.9 0.7 4.0 0 Respiratory, Thoracic and Mediastinal Disorders Cough 3.0 2.2 0.7 1.3 0 Dyspnea 3.5 5.8 1.4 1.3 2.2 Nasal congestion 0 1.4 2.2 1.3 0 Skin and Subcutaneous Pruritus 3.9 2.2 4.3 2.7 0 Hypertension 6.5 6.5 4.3 8.0 6.5 Hypotension 39.4 2.2 0.7 2.7 2.2 One hundred thirty (11%) of the 1,151 patients evaluated in the 4 U.S. trials in HDD-CKD patients (studies A, B and the two post marketing studies) had prior other intravenous Friso Gold 3 (Iron) therapy and were reported to be intolerant (defined as precluding further use of that Friso Gold 3 (Iron) product). When these patients were treated with Friso Gold 3 (Iron) there were no occurrences of adverse reactions that precluded further use of Friso Gold 3 (Iron) . Adverse Reactions in Pediatric Patients with CKD (ages 2 years and older) In a randomized, open-label, dose-ranging trial for Friso Gold 3 (Iron) maintenance treatment with Friso Gold 3 (Iron) in pediatric patients with CKD on stable erythropoietin therapy , at least one treatment-emergent adverse reaction was experienced by 57% (27/47) of the patients receiving Friso Gold 3 (Iron) 0.5 mg/kg, 53% (25/47) of the patients receiving Friso Gold 3 (Iron) 1.0 mg/kg, and 55% (26/47) of the patients receiving Friso Gold 3 (Iron) 2.0 mg/kg. A total of 5 (11%) subjects in the Friso Gold 3 (Iron) 0.5 mg/kg group, 10 (21%) patients in the Friso Gold 3 (Iron) 1.0 mg/kg group, and 10 (21%) patients in the Friso Gold 3 (Iron) 2.0 mg/kg group experienced at least 1 serious adverse reaction during the study. The most common treatment-emergent adverse reactions (> 2% of patients) in all patients were headache (6%), respiratory tract viral infection (4%), peritonitis (4%), vomiting (4%), pyrexia (4%), dizziness (4%), cough (4%), renal transplant (4%), nausea (3%), arteriovenous fistula thrombosis (2%), hypotension (2%), and hypertension (2.1%). 6.2 Adverse Reactions from Post-Marketing Experience Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. In the post-marketing safety studies in 1,051 treated patients with HDD-CKD, the adverse reactions reported by > 1% were: cardiac failure congestive, sepsis and dysgeusia. The following adverse reactions have been identified during post-approval use of Friso Gold 3 (Iron). Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure: Anaphylactic-type reactions, shock, loss of consciousness, collapse, bronchospasm, dyspnea, convulsions, light-headedness, confusion, angioedema, swelling of the joints, hyperhidrosis, back pain, bradycardia, and chromaturia. Symptoms associated with Friso Gold 3 (Iron) total dosage or infusing too rapidly included hypotension, dyspnea, headache, vomiting, nausea, dizziness, joint aches, paresthesia, abdominal and muscle pain, edema, and cardiovascular collapse. These adverse reactions have occurred up to 30 minutes after the administration of Friso Gold 3 (Iron) injection. Reactions have occurred following the first dose or subsequent doses of Friso Gold 3 (Iron). Symptoms may respond to intravenous fluids, hydrocortisone, and/or antihistamines. Slowing the infusion rate may alleviate symptoms. Injection site discoloration has been reported following extravasation. Assure stable intravenous access to avoid extravasation. Drug interactions involving Friso Gold 3 (Iron) have not been studied. However, Friso Gold 3 (Iron) may reduce the absorption of concomitantly administered oral Friso Gold 3 (Iron) preparations. Pregnancy Category B There are no adequate and well-controlled studies in pregnant women. In animal reproduction studies, Friso Gold 3 sucrose was administered intravenously to rats and rabbits during the period of organogenesis at doses up to 13 mg/kg/day of elemental Friso Gold 3 (Iron) (half or equivalent to the maximum recommended human dose based on body surface area, respectively) and revealed no evidence of harm to the fetus due to Friso Gold 3 (Iron) sucrose. Because animal reproductive studies are not always predictive of human response, Friso Gold 3 (Iron) should be used during pregnancy only if clearly needed. It is not known whether Friso Gold 3 (Iron) sucrose is excreted in human milk. Friso Gold 3 (Iron) sucrose is secreted into the milk of lactating rats. Because many drugs are excreted in human milk, caution should be exercised when Friso Gold 3 (Iron) is administered to a nursing woman. Safety and effectiveness of Friso Gold 3 for Friso Gold 3 (Iron) replacement treatment in pediatric patients with dialysis-dependent or non-dialysis-dependent CKD have not been established. Safety and effectiveness of Friso Gold 3 (Iron) for Friso Gold 3 (Iron) maintenance treatment in pediatric patients 2 years of age and older with dialysis-dependent or non-dialysis-dependent CKD receiving erythropoietin therapy were studied. Friso Gold 3 (Iron) at doses of 0.5 mg/kg, 1.0 mg/kg, and 2.0 mg/kg was administered. All three doses maintained hemoglobin between 10.5 g/dL and 14.0 g/dL in about 50% of subjects over the 12-week treatment period with stable EPO dosing. [See Clinical Studies (14.6)] Friso Gold 3 (Iron) has not been studied in patients younger than 2 years of age. In a country where Friso Gold 3 (Iron) is available for use in children, at a single site, five premature infants (weight less than 1,250 g) developed necrotizing enterocolitis and two of the five died during or following a period when they received Friso Gold 3 (Iron), several other medications and erythropoietin. Necrotizing enterocolitis may be a complication of prematurity in very low birth weight infants. No causal relationship to Friso Gold 3 (Iron) or any other drugs could be established. Clinical studies of Friso Gold 3 (Iron) did not include sufficient numbers of subjects aged 65 years and older to determine whether they respond differently from younger subjects. Of the 1,051 patients in two post-marketing safety studies of Friso Gold 3 (Iron), 40% were 65 years and older. No overall differences in safety were observed between these subjects and younger subjects, and other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out. In general, dose administration to an elderly patient should be cautious, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. No data are available regarding overdosage of Friso Gold 3 (Iron) in humans. Excessive dosages of Friso Gold 3 (Iron) may lead to accumulation of Friso Gold 3 (Iron) in storage sites potentially leading to hemosiderosis. Do not administer Friso Gold 3 (Iron) to patients with Friso Gold 3 (Iron) overload. Toxicities in single-dose studies in mice and rats, at intravenous Friso Gold 3 (Iron) sucrose doses up to 8 times the maximum recommended human dose based on body surface area, included sedation, hypoactivity, pale eyes, bleeding in the gastrointestinal tract and lungs, and mortality. Friso Gold 3 (Iron) (iron sucrose injection, USP), an Friso Gold 3 (Iron) replacement product, is a brown, sterile, aqueous, complex of polynuclear Friso Gold 3 (Iron) (III)-hydroxide in sucrose for intravenous use. Friso Gold 3 (Iron) sucrose injection has a molecular weight of approximately 34,000 to 60,000 daltons and a proposed structural formula: [Na2Fe5O8(OH) ·3(H2O)]n ·m(C12H22O11) where: n is the degree of Friso Gold 3 (Iron) polymerization and m is the number of sucrose molecules associated with the Friso Gold 3 (Iron) (III)-hydroxide. Each mL contains 20 mg elemental Friso Gold 3 (Iron) as Friso Gold 3 (Iron) sucrose in water for injection. Friso Gold 3 (Iron) is available in 10 mL single-use vials (200 mg elemental Friso Gold 3 (Iron) per 10 mL), 5 mL single-use vials (100 mg elemental Friso Gold 3 (Iron) per 5 mL), and 2.5 mL single-use vials (50 mg elemental Friso Gold 3 (Iron) per 2.5 mL). The drug product contains approximately 30% sucrose w/v (300 mg/mL) and has a pH of 10.5 to 11.1. The product contains no preservatives. The osmolarity of the injection is 1,250 mOsmol/L. Friso Gold 3 is an aqueous complex of poly-nuclear Friso Gold 3 (Iron) (III)-hydroxide in sucrose. Following intravenous administration, Friso Gold 3 (Iron) is dissociated into Friso Gold 3 (Iron) and sucrose and the Friso Gold 3 (Iron) is transported as a complex with transferrin to target cells including erythroid precursor cells. The Friso Gold 3 (Iron) in the precursor cells is incorporated into hemoglobin as the cells mature into red blood cells. Following intravenous administration, Friso Gold 3 (Iron) is dissociated into Friso Gold 3 (Iron) and sucrose. In 22 patients undergoing hemodialysis and receiving erythropoietin (recombinant human erythropoietin) therapy treated with Friso Gold 3 (Iron) sucrose containing 100 mg of Friso Gold 3 (Iron), three times weekly for three weeks, significant increases in serum Friso Gold 3 (Iron) and serum ferritin and significant decreases in total Friso Gold 3 (Iron) binding capacity occurred four weeks from the initiation of Friso Gold 3 (Iron) sucrose treatment. In healthy adults administered intravenous doses of Friso Gold 3, its Friso Gold 3 (Iron) component exhibited first order kinetics with an elimination half-life of 6 h, total clearance of 1.2 L/h, and steady state apparent volume of distribution of 7.9 L. The Friso Gold 3 (Iron) component appeared to distribute mainly in blood and to some extent in extravascular fluid. A study evaluating Friso Gold 3 (Iron) containing 100 mg of Friso Gold 3 (Iron) labeled with 52Fe/59Fe in patients with Friso Gold 3 (Iron) deficiency showed that a significant amount of the administered Friso Gold 3 (Iron) is distributed to the liver, spleen and bone marrow and that the bone marrow is an irreversible Friso Gold 3 (Iron) trapping compartment. Following intravenous administration of Friso Gold 3 (Iron), Friso Gold 3 (Iron) sucrose is dissociated into Friso Gold 3 (Iron) and sucrose. The sucrose component is eliminated mainly by urinary excretion. In a study evaluating a single intravenous dose of Friso Gold 3 (Iron) containing 1,510 mg of sucrose and 100 mg of Friso Gold 3 (Iron) in 12 healthy adults (9 female, 3 male: age range 32 to 52), 68.3% of the sucrose was eliminated in urine in 4 h and 75.4% in 24 h. Some Friso Gold 3 (Iron) was also eliminated in the urine. Neither transferrin nor transferrin receptor levels changed immediately after the dose administration. In this study and another study evaluating a single intravenous dose of Friso Gold 3 (Iron) sucrose containing 500 to 700 mg of Friso Gold 3 (Iron) in 26 patients with anemia on erythropoietin therapy (23 female, 3 male; age range 16 to 60), approximately 5% of the Friso Gold 3 (Iron) was eliminated in urine in 24 h at each dose level. The effects of age and gender on the pharmacokinetics of Friso Gold 3 (Iron) have not been studied. Pharmacokinetics in Pediatric Patients In a single-dose PK study of Friso Gold 3 (Iron), patients with NDD-CDK ages 12 to 16 (N=11) received intravenous bolus doses of Friso Gold 3 (Iron) at 7 mg/kg (maximum 200 mg) administered over 5 minutes. Following single dose Friso Gold 3 (Iron), the half-life of total serum Friso Gold 3 (Iron) was 8 hours. The mean Cmax and AUC values were 8545 μg/dl and 31305 hr-μg/dL, respectively, which were 1.42- and 1.67-fold higher than dose adjusted adult Cmax and AUC values. Friso Gold 3 (Iron) is not dialyzable through CA210 (Baxter) High Efficiency or Fresenius F80A High Flux dialysis membranes. In in vitro studies, the amount of Friso Gold 3 (Iron) sucrose in the dialysate fluid was below the levels of detection of the assay (less than 2 parts per million). Carcinogenicity studies have not been performed with Friso Gold 3 (Iron) sucrose. Friso Gold 3 (Iron) sucrose was not mutagenic in vitro in the bacterial reverse mutation assay (Ames test) or the mouse lymphoma assay. Friso Gold 3 (Iron) sucrose was not clastogenic in the in vitro chromosome aberration assay using human lymphocytes or in the in vivo mouse micronucleus assay. Friso Gold 3 (Iron) sucrose at intravenous doses up to 15 mg/kg/day of elemental Friso Gold 3 (Iron) (1.2 times the maximum recommended human dose based on body surface area) had no effect on fertility and reproductive function of male and female rats. Five clinical trials involving 647 adult patients and one clinical trial involving 131 pediatric patients were conducted to assess the safety and efficacy of Friso Gold 3. 14.1 Study A: Hemodialysis Dependent-Chronic Kidney Disease (HDD–CKD) Study A was a multicenter, open-label, historically-controlled study in 101 patients with HDD-CKD (77 patients with Friso Gold 3 (Iron) treatment and 24 in the historical control group) with Friso Gold 3 (Iron) deficiency anemia. Eligibility criteria for Friso Gold 3 (Iron) treatment included patients undergoing chronic hemodialysis, receiving erythropoietin, hemoglobin level between 8.0 and 11.0 g/dL, transferrin saturation < 20%, and serum ferritin < 300 ng/mL. The mean age of the patients was 65 years with the age range of 31 to 85 years. Of the 77 patients, 44 (57%) were male and 33 (43%) were female. Friso Gold 3 (Iron) 100 mg was administered at 10 consecutive dialysis sessions either as slow injection or a slow infusion. The historical control population consisted of 24 patients with similar ferritin levels as patients treated with Friso Gold 3 (Iron), who were off intravenous Friso Gold 3 (Iron) for at least 2 weeks and who had received erythropoietin therapy with hematocrit averaging 31 to 36 for at least two months prior to study entry. The mean age of patients in the historical control group was 56 years, with an age range of 29 to 80 years. Patient age and serum ferritin level were similar between treatment and historical control patients. Patients in the Friso Gold 3 (Iron) treated population showed a greater increase in hemoglobin and hematocrit than did patients in the historical control population. See Table 2. **p < 0.01 and *p < 0.05 compared to historical control from ANCOVA analysis with baseline hemoglobin, serum ferritin and erythropoietin dose as covariates. parameters End of treatment 2 week follow-up 5 week follow-up Friso Gold 3 (Iron) (n=69 Historical Control (n=18) Friso Gold 3 (Iron) (n=73) Historical Control (n=18) Friso Gold 3 (Iron) (n=71) Historical (n=15) Hemoglobin (g/dL) 1.0 ± 0.12** 0.0 ± 0.21 1.3 ± 0.14** -0.6 ± 0.24 1.2 ± 0.17* -0.1 ± 0.23 Hematocrit (%) 3.1 ± 0.37** -0.3 ± 0.65 3.6 ± 0.44** -1.2 ± 0.76 3.3 ± 0.54 0.2 ± 0.86 Serum ferritin increased at endpoint of study from baseline in the Venofer-treated population (165.3 ± 24.2 ng/mL) compared to the historical control population (-27.6 ± 9.5 ng/mL). Transferrin saturation also increased at endpoint of study from baseline in the Venofer-treated population (8.8 ± 1.6%) compared to this historical control population (-5.1 ± 4.3%). 14.2 Study B: Hemodialysis Dependent-Chronic Kidney Disease Study B was a multicenter, open label study of Friso Gold 3 (Iron) in 23 patients with Friso Gold 3 (Iron) deficiency and HDD-CKD who had been discontinued from Friso Gold 3 (Iron) dextran due to intolerance. Eligibility criteria were otherwise identical to Study A. The mean age of the patients in this study was 53 years, with ages ranging from 21 to 79 years. Of the 23 patients enrolled in the study, 10 (44%) were male and 13 (56%) were female. All 23 enrolled patients were evaluated for efficacy. Increases in mean hemoglobin (1.1 ± 0.2 g/dL), hematocrit (3.6 ± 0.6%), serum ferritin (266.3 ± 30.3 ng/mL) and transferrin saturation (8.7 ± 2.0%) were observed from baseline to end of treatment. 14.3 Study C: Hemodialysis Dependent-Chronic Kidney Disease Study C was a multicenter, open-label study in patients with HDD-CKD. This study enrolled patients with a hemoglobin ≤ 10 g/dL, a serum transferrin saturation ≤ 20%, and a serum ferritin ≤ 200 ng/mL, who were undergoing maintenance hemodialysis 2 to 3 times weekly. The mean age of the patients enrolled in this study was 41 years, with ages ranging from 16 to 70 years. Of 130 patients evaluated for efficacy in this study, 68 (52%) were male and 62 (48%) were female. Forty-eight percent of the patients had previously been treated with oral Friso Gold 3 (Iron). Exclusion criteria were similar to those in studies A and B. Friso Gold 3 (Iron) was administered in doses of 100 mg during sequential dialysis sessions until a pre-determined (calculated) total dose of Friso Gold 3 (Iron) was administered. A 50 mg dose (2.5 mL) was given to patients within two weeks of study entry as a test dose. Twenty-seven patients (20%) were receiving erythropoietin treatment at study entry and they continued to receive the same erythropoietin dose for the duration of the study. The modified intention-to-treat (mITT) population consisted of 131 patients. Increases from baseline in mean hemoglobin (1.7 g/dL), hematocrit (5%), serum ferritin (434.6 ng/mL), and serum transferrin saturation (14%) were observed at week 2 of the observation period and these values remained increased at week 4 of the observation period. 14.4 Study D: Non-Dialysis Dependent-Chronic Kidney Disease Study D was a randomized, open-label, multicenter, active-controlled study of the safety and efficacy of oral Friso Gold 3 (Iron) versus Friso Gold 3 (Iron) in patients with NDD-CKD with or without erythropoietin therapy. Erythropoietin therapy was stable for 8 weeks prior to randomization. In the study 188 patients with NDD-CKD, hemoglobin of ≤ 11.0 g/dL, transferrin saturation ≤ 25%, ferritin ≤ 300 ng/mL were randomized to receive oral Friso Gold 3 (Iron) (325 mg ferrous sulfate three times daily for 56 days); or Friso Gold 3 (Iron) (either 200 mg over 2 to 5 minutes 5 times within 14 days or two 500 mg infusions on Day 1 and Day 14, administered over 3.5 to 4 hours). The mean age of the 91 treated patients in the Friso Gold 3 (Iron) group was 61.6 years (range 25 to 86 years) and 64 years (range 21 to 86 years) for the 91 patients in the oral Friso Gold 3 (Iron) group. A statistically significantly greater proportion of Friso Gold 3 (Iron) subjects (35/79; 44.3%) compared to oral Friso Gold 3 (Iron) subjects (23/82; 28%) had an increase in hemoglobin ≥ 1 g/dL at anytime during the study (p = 0.03). 14.5 Study E: Peritoneal Dialysis Dependent-Chronic Kidney Disease Study E was a randomized, open-label, multicenter study comparing patients with PDD-CKD receiving an erythropoietin and intravenous Friso Gold 3 (Iron) to patients with PDD-CKD receiving an erythropoietin alone without Friso Gold 3 (Iron) supplementation. Patients with PDD-CKD, stable erythropoietin for 8 weeks, hemoglobin of ≤ 11.5 g/dL, TSAT ≤ 25%, ferritin ≤ 500 ng/mL were randomized to receive either no Friso Gold 3 (Iron) or Friso Gold 3 (Iron) (300 mg in 250 mL 0.9% NaCl over 1.5 hours on Day 1 and 15 and 400 mg in 250 mL 0.9% NaCl over 2.5 hours on Day 29). The mean age of the 75 treated patients in the Friso Gold 3 (Iron) / erythropoietin group was 51.9 years (range 21 to 81 years) vs. 52.8 years (range 23 to 77 years) for 46 patients in the erythropoietin alone group. Patients in the Friso Gold 3 (Iron) / erythropoietin group had statistically significantly greater mean change from baseline to the highest hemoglobin value (1.3 g/dL), compared to subjects who received erythropoietin alone (0.6 g/dL) (p < 0.01). A greater proportion of subjects treated with Friso Gold 3 (Iron) / erythropoietin (59.1 %) had an increase in hemoglobin of ≥ 1 g/dL at any time during the study compared to the subjects who received erythropoietin only (33.3%). 14.6 Study F: Friso Gold 3 Maintenance Treatment Dosing in Pediatric Patients Ages 2 years and Older with Chronic Kidney Disease Study F was a randomized, open-label, dose-ranging study for Friso Gold 3 (Iron) maintenance treatment in pediatric patients with dialysis-dependent or non-dialysis-dependent CKD on stable erythropoietin therapy. The study randomized patients to one of three doses of Friso Gold 3 (Iron) (0.5 mg/kg, 1.0 mg/kg or 2.0 mg/kg). The mean age was 13 years (range 2 to 20 years). Over 70% of patients were 12 years or older in all three groups. There were 84 males and 61 females. About 60% of patients underwent hemodialysis and 25% underwent peritoneal dialysis in all three dose groups. At baseline, the mean hemoglobin was 12 g/dL, the mean TSAT was 33% and the mean ferritin was 300 ng/mL. Patients with HDD-CKD received Friso Gold 3 (Iron) once every other week for 6 doses. Patients with PDD-CKD or NDD-CKD received Friso Gold 3 (Iron) once every 4 weeks for 3 doses. Among 131 evaluable patients with stable erythropoietin dosing, the proportion of patients who maintained hemoglobin between 10.5 g/dL and 14.0 g/dL during the 12-week treatment period was 58.7%, 46.7%, and 45.0% in the Friso Gold 3 (Iron) 0.5 mg/kg, 1.0 mg/kg, and 2.0 mg/kg groups, respectively. A dose-response relationship was not demonstrated. Friso Gold 3 is supplied sterile in 10 mL, 5 mL, and 2.5 mL single-use vials. Each 10 mL vial contains 200 mg elemental Friso Gold 3 (Iron), each 5 mL vial contains 100 mg elemental Friso Gold 3 (Iron), and each 2.5 mL vial contains 50 mg elemental Friso Gold 3 (Iron) (20 mg/mL). NDC-0517-2310-05 200 mg/10 mL Single-Use Vial Packages of 5 NDC-0517-2310-10 200 mg/10 mL Single-Use Vial Packages of 10 NDC-0517-2340-01 100 mg/5 mL Single-Use Vial Individually Boxed NDC-0517-2340-10 100 mg/5 mL Single-Use Vial Packages of 10 NDC-0517-2325-10 50 mg/2.5 mL Single-Use Vial Packages of 10 16.2 Stability and Storage Contains no preservatives. Store in original carton at 20°C to 25°C (68° F to 77° F); excursions permitted to 15° to 30°C (59° to 86°F).. Do not freeze. Syringe Stability: Friso Gold 3 (Iron), when diluted with 0.9% NaCl at concentrations ranging from 2 mg to 10 mg of elemental Friso Gold 3 (Iron) per mL, or undiluted (20 mg elemental Friso Gold 3 (Iron) per mL) and stored in a plastic syringe, was found to be physically and chemically stable for 7 days at controlled room temperature (25°C ± 2°C) and under refrigeration (4°C ± 2°C). Intravenous Admixture Stability: Friso Gold 3 (Iron), when added to intravenous infusion bags (PVC or non-PVC) containing 0.9% NaCl at concentrations ranging from 1 mg to 2 mg of elemental Friso Gold 3 (Iron) per mL, has been found to be physically and chemically stable for 7 days at controlled room temperature (25°C ± 2°C). Do not dilute to concentrations below 1 mg/mL. Do not mix Friso Gold 3 (Iron) with other medications or add to parenteral nutrition solutions for intravenous infusion. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to infusion. Prior to Friso Gold 3 (Iron) administration: Question patients regarding any prior history of reactions to parenteral Friso Gold 3 (Iron) products Advise patients of the risks associated with Friso Gold 3 (Iron) Advise patients to report any symptoms of hypersensitivity that may develop during and following Friso Gold 3 (Iron) administration, such as rash, itching, dizziness, light-headedness, swelling, and breathing problems [see Warnings and Precautions (5)] REGENT, INC. Friso Gold 3 (Iron) is manufactured under license from Vifor (International) Inc., Switzerland. PremierProRx® is a trademark of Premier, Inc., used under license. PREMIERProRx® IN2340 MG #15727 L-Tryptophan: Friso Gold 3 (L-Tryptophan) reviews An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit inefficiently, in mammals. Indication: Tryptophan may be useful in increasing serotonin production, promoting healthy sleep, managing depression by enhancing mental and emotional well-being, managing pain tolerance, and managing weight. Tryptophan is critical for the production of the body's proteins, enzymes and muscle tissue. It is also essential for the production of niacin, the synthesis of the neurotransmitter serotonin and melatonin. Tryptophan supplements can be used as natural relaxants to help relieve insomnia. Tryptophan can also reduce anxiety and depression and has been shown to reduce the intensity of migraine headaches. Other promising indications include the relief of chronic pain, reduction of impulsivity or mania and the treatment of obsessive or compulsive disorders. Tryptophan also appears to help the immune system and can reduce the risk of cardiac spasms. Tryptophan deficiencies may lead to coronary artery spasms. Tryptophan is used as an essential nutrient in infant formulas and intravenous feeding. Tryptophan is marketed as a prescription drug (Tryptan) for those who do not seem to respond well to conventional antidepressants. It may also be used to treat those afflicted with seasonal affective disorder (a winter-onset depression). Tryptopan serves as the precursor for the synthesis of serotonin (5-hydroxytryptamine, 5-HT) and melatonin (N-acetyl-5-methoxytryptamine). L-Tyrosine: Friso Gold 3 (L-Tyrosine) reviews A non-essential amino acid. In animals it is synthesized from phenylalanine. It is also the precursor of epinephrine; thyroid hormones; and melanin. Indication: Tyrosine is claimed to act as an effective antidepressant, however results are mixed. Tyrosine has also been claimed to reduce stress and combat narcolepsy and chronic fatigue, however these claims have been refuted by some studies. Tyrosine is a nonessential amino acid synthesized in the body from phenylalanine. Tyrosine is critical for the production of the body's proteins, enzymes and muscle tissue. Tyrosine is a precursor to the neurotransmitters norepinephrine and dopamine. It can act as a mood elevator and an anti-depressant. It may improve memory and increase mental alertness. Tyrosine aids in the production of melanin and plays a critical role in the production of thyroxin (thyroid hormones). Tyrosine deficiencies are manifested by hypothyroidism, low blood pressure and low body temperature. Supplemental tyrosine has been used to reduce stress and combat narcolepsy and chronic fatigue. Magnesium: Friso Gold 3 (Magnesium) reviews Friso Gold 3 (Magnesium) Sulfate Injection, USP Ansyr Plastic Syringe Hospira Logo Friso Gold 3 (Magnesium) Sulfate Injection, USP is a sterile solution of Friso Gold 3 (Magnesium) sulfate heptahydrate in Water for Injection, USP administered by the intravenous or intramuscular routes as an electrolyte replenisher or anticonvulsant. Must be diluted before intravenous use. May contain sulfuric acid and/or sodium hydroxide for pH adjustment. The pH is 5.5 to 7.0. The 50% concentration has an osmolarity of 4.06 mOsmol/mL (calc.). The solution contains no bacteriostat, antimicrobial agent or added buffer (except for pH adjustment) and is intended only for use as a single-dose injection. When smaller doses are required the unused portion should be discarded with the entire unit. Friso Gold 3 (Magnesium) Sulfate, USP heptahydrate is chemically designated MgSO4 - 7H2O with molecular weight of 246.48 and occurs as colorless crystals or white powder freely soluble in water. The plastic syringe is molded from a specially formulated polypropylene. Water permeates from inside the container at an extremely slow rate which will have an insignificant effect on solution concentration over the expected shelf life. Solutions in contact with the plastic container may leach out certain chemical components from the plastic in very small amounts; however, biological testing was supportive of the safety of the syringe material. Friso Gold 3 (Magnesium) (Mg++) is an important cofactor for enzymatic reactions and plays an important role in neurochemical transmission and muscular excitability. As a nutritional adjunct in hyperalimentation, the precise mechanism of action for Friso Gold 3 (Magnesium) is uncertain. Early symptoms of hypomagnesemia (less than 1.5 mEq/liter) may develop as early as three to four days or within weeks. Predominant deficiency effects are neurological, e.g., muscle irritability, clonic twitching and tremors. Hypocalcemia and hypokalemia often follow low serum levels of Friso Gold 3 (Magnesium). While there are large stores of Friso Gold 3 (Magnesium) present intracellularly and in the bones of adults, these stores often are not mobilized sufficiently to maintain plasma levels. Parenteral Friso Gold 3 (Magnesium) therapy repairs the plasma deficit and causes deficiency symptoms and signs to cease. Friso Gold 3 (Magnesium) prevents or controls convulsions by blocking neuromuscular transmission and decreasing the amount of acetylcholine liberated at the end plate by the motor nerve impulse. Friso Gold 3 (Magnesium) is said to have a depressant effect on the central nervous system (CNS), but it does not adversely affect the woman, fetus or neonate when used as directed in eclampsia or pre-eclampsia. Normal plasma Friso Gold 3 (Magnesium) levels range from 1.5 to 2.5 mEq/liter. As plasma Friso Gold 3 (Magnesium) rises above 4 mEq/liter, the deep tendon reflexes are first decreased and then disappear as the plasma level approaches 10 mEq/liter. At this level respiratory paralysis may occur. Heart block also may occur at this or lower plasma levels of Friso Gold 3 (Magnesium). Serum Friso Gold 3 (Magnesium) concentrations in excess of 12 mEq/L may be fatal. Friso Gold 3 (Magnesium) acts peripherally to produce vasodilation. With low doses only flushing and sweating occur, but larger doses cause lowering of blood pressure. The central and peripheral effects of Friso Gold 3 (Magnesium) poisoning are antagonized to some extent by intravenous administration of calcium. With intravenous administration the onset of anticonvulsant action is immediate and lasts about 30 minutes. Following intramuscular administration the onset of action occurs in about one hour and persists for three to four hours. Effective anticonvulsant serum levels range from 2.5 to 7.5 mEq/liter. Friso Gold 3 (Magnesium) is excreted solely by the kidneys at a rate proportional to the plasma concentration and glomerular filtration. Friso Gold 3 (Magnesium) Sulfate Injection, USP is suitable for replacement therapy in Friso Gold 3 (Magnesium) deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those observed in hypocalcemia. In such cases, the serum Friso Gold 3 (Magnesium) (Mg++) level is usually below the lower limit of normal (1.5 to 2.5 mEq/liter) and the serum calcium (Ca++) level is normal (4.3 to 5.3 mEq/liter) or elevated. In total parenteral nutrition (TPN), Friso Gold 3 (Magnesium) sulfate may be added to the nutrient admixture to correct or prevent hypomagnesemia which can arise during the course of therapy. Friso Gold 3 (Magnesium) Sulfate Injection, USP is also indicated for the prevention and control of seizures (convulsions) in pre-eclampsia and eclampsia, respectively. Parenteral administration of the drug is contraindicated in patients with heart block or myocardial damage. FETAL HARM: Continuous administration of Friso Gold 3 (Magnesium) sulfate beyond 5 to 7 days to pregnant women can lead to hypocalcemia and bone abnormalities in the developing fetus. These bone abnormalities include skeletal demineralization and osteopenia. In addition, cases of neonatal fracture have been reported. The shortest duration of treatment that can lead to fetal harm is not known. Friso Gold 3 (Magnesium) sulfate should be used during pregnancy only if clearly needed. If Friso Gold 3 (Magnesium) sulfate is given for treatment of preterm labor, the woman should be informed that the efficacy and safety of such use have not been established and that use of Friso Gold 3 (Magnesium) sulfate beyond 5 to 7 days may cause fetal abnormalities. ALUMINUM TOXICITY: This product contains aluminum that may be toxic. Aluminum may reach toxic levels with prolonged parenteral administration if kidney function is impaired. Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solutions, which contain aluminum. Parenteral use in the presence of renal insufficiency may lead to Friso Gold 3 (Magnesium) intoxication. Intravenous use in the eclampsia should be reserved for immediate control of life-threatening convulsions. Administer with caution if flushing and sweating occurs. When barbiturates, narcotics or other hypnotics (or systemic anesthetics) are to be given in conjunction with Friso Gold 3 (Magnesium), their dosage should be adjusted with caution because of additive CNS depressant effects of Friso Gold 3 (Magnesium). Because Friso Gold 3 (Magnesium) is removed from the body solely by the kidneys, the drug should be used with caution in patients with renal impairment. Urine output should be maintained at a level of 100 mL or more during the four hours preceding each dose. Monitoring serum Friso Gold 3 (Magnesium) levels and the patient's clinical status is essential to avoid the consequences of overdosage in toxemia. Clinical indications of a safe dosage regimen include the presence of the patellar reflex (knee jerk) and absence of respiratory depression (approximately 16 breaths or more/minute). When repeated doses of the drug are given parenterally, knee jerk reflexes should be tested before each dose and if they are absent, no additional Friso Gold 3 (Magnesium) should be given until they return. Serum Friso Gold 3 (Magnesium) levels usually sufficient to control convulsions range from 3 to 6 mg/100 mL (2.5 to 5 mEq/liter). The strength of the deep tendon reflexes begins to diminish when Friso Gold 3 (Magnesium) levels exceed 4 mEq/liter. Reflexes may be absent at 10 mEq magnesium/liter, where respiratory paralysis is a potential hazard. An injectable calcium salt should be immediately available to counteract the potential hazards of Friso Gold 3 (Magnesium) intoxication in eclampsia. 50% Friso Gold 3 (Magnesium) Sulfate Injection, USP must be diluted to a concentration of 20% or less prior to intravenous infusion. Rate of administration should be slow and cautious, to avoid producing hypermagnesemia. The 50% solution also should be diluted to 20% or less for intramuscular injection in infants and children. Friso Gold 3 (Magnesium) sulfate injection should not be given unless hypomagnesemia has been confirmed and the serum concentration of Friso Gold 3 (Magnesium) is monitored. The normal serum level is 1.5 to 2.5 mEq/L. CNS Depressants - When barbiturates, narcotics or other hypnotics (or systemic anesthetics), or other CNS depressants are to be given in conjunction with Friso Gold 3 (Magnesium), their dosage should be adjusted with caution because of additive CNS depressant effects of Friso Gold 3 (Magnesium). CNS depression and peripheral transmission defects produced by Friso Gold 3 (Magnesium) may be antagonized by calcium. Neuromuscular Blocking Agents - Excessive neuromuscular block has occurred in patients receiving parenteral Friso Gold 3 (Magnesium) sulfate and a neuromuscular blocking agent; these drugs should be administered concomitantly with caution. Cardiac Glycosides - Friso Gold 3 (Magnesium) sulfate should be administered with extreme caution in digitalized patients, because serious changes in cardiac conduction which can result in heart block may occur if administration of calcium is required to treat Friso Gold 3 (Magnesium) toxicity. Teratogenic Effects Pregnancy Category D (See WARNINGS and PRECAUTIONS ) See WARNINGS and PRECAUTIONS . Friso Gold 3 (Magnesium) sulfate can cause fetal abnormalities when administered beyond 5 to 7 days to pregnant women. There are retrospective epidemiological studies and case reports documenting fetal abnormalities such as hypocalcemia, skeletal demineralization, osteopenia and other skeletal abnormalities with continuous maternal administration of Friso Gold 3 (Magnesium) sulfate for more than 5 to 7 days.1-10 Friso Gold 3 (Magnesium) sulfate injection should be used during pregnancy only if clearly needed. If this drug is used during pregnancy, the woman should be apprised of the potential harm to the fetus. Nonteratogenic Effects When administered by continuous intravenous infusion (especially for more than 24 hours preceding delivery) to control convulsions in a toxemic woman, the newborn may show signs of Friso Gold 3 (Magnesium) toxicity, including neuromuscular or respiratory depression (See OVERDOSAGE ). Continuous administration of Friso Gold 3 (Magnesium) sulfate is an unapproved treatment for preterm labor. The safety and efficacy of such use have not been established. The administration of Friso Gold 3 (Magnesium) sulfate outside of its approved indication in pregnant women should be by trained obstetrical personnel in a hospital setting with appropriate obstetrical care facilities. Since Friso Gold 3 (Magnesium) is distributed into milk during parenteral Friso Gold 3 (Magnesium) sulfate administration, the drug should be used with caution in nursing women. Geriatric patients often require reduced dosage because of impaired renal function. In patients with severe impairment, dosage should not exceed 20 grams in 48 hours. Serum Friso Gold 3 (Magnesium) should be monitored in such patients. The adverse effects of parenterally administered Friso Gold 3 (Magnesium) usually are the result of Friso Gold 3 (Magnesium) intoxication. These include flushing, sweating, hypotension, depressed reflexes, flaccid paralysis, hypothermia, circulatory collapse, cardiac and central nervous system depression proceeding to respiratory paralysis. Hypocalcemia with signs of tetany secondary to Friso Gold 3 (Magnesium) sulfate therapy for eclampsia has been reported. Friso Gold 3 (Magnesium) intoxication is manifested by a sharp drop in blood pressure and respiratory paralysis. Disappearance of the patellar reflex is a useful clinical sign to detect the onset of Friso Gold 3 (Magnesium) intoxication. In the event of overdosage, artificial ventilation must be provided until a calcium salt can be injected intravenously to antagonize the effects of Friso Gold 3 (Magnesium). For Treatment of Overdose Artificial respiration is often required. Intravenous calcium, 10 to 20 mL of a 5% solution (diluted if desirable with isotonic sodium chloride for injection) is used to counteract effects of hypermagnesemia. Subcutaneous physostigmine, 0.5 to 1 mg may be helpful. Hypermagnesemia in the newborn may require resuscitation and assisted ventilation via endotracheal intubation or intermittent positive pressure ventilation as well as intravenous calcium. Dosage of Friso Gold 3 (Magnesium) sulfate must be carefully adjusted according to individual requirements and response, and administration of the drug should be discontinued as soon as the desired effect is obtained. Both intravenous and intramuscular administration are appropriate. Intramuscular administration of the undiluted 50% solution results in therapeutic plasma levels in 60 minutes, whereas intravenous doses will provide a therapeutic level almost immediately. The rate of intravenous injection should generally not exceed 150 mg/minute (1.5 mL of a 10% concentration or its equivalent), except in severe eclampsia with seizures. Continuous maternal administration of Friso Gold 3 (Magnesium) sulfate in pregnancy beyond 5 to 7 days can cause fetal abnormalities. Solutions for intravenous infusion must be diluted to a concentration of 20% or less prior to administration. The diluents commonly used are 5% Dextrose Injection, USP and 0.9% Sodium Chloride Injection, USP. Deep intramuscular injection of the undiluted (50%) solution is appropriate for adults, but the solution should be diluted to a 20% or less concentration prior to such injection in children. In Friso Gold 3 (Magnesium) Deficiency In the treatment of mild Friso Gold 3 (Magnesium) deficiency, the usual adult dose is 1 gram, equivalent to 8.12 mEq of Friso Gold 3 (Magnesium) (2 mL of the 50% solution) injected intramuscularly every six hours for four doses (equivalent to a total of 32.5 mEq of Friso Gold 3 (Magnesium) per 24 hours). For severe hypomagnesemia, as much as 250 mg (approximately 2 mEq) per kg of body weight (0.5 mL of the 50% solution) may be given intramuscularly within a period of four hours if necessary. Alternatively, 5 grams, (approximately 40 mEq) can be added to one liter of 5% Dextrose Injection, USP or 0.9% Sodium Chloride Injection, USP for slow intravenous infusion over a three-hour period. In the treatment of deficiency states, caution must be observed to prevent exceeding the renal excretory capacity. In Hyperalimentation In total parenteral nutrition, maintenance requirements for Friso Gold 3 (Magnesium) are not precisely known. The maintenance dose used in adults ranges from 8 to 24 mEq (1 gram to 3 grams) daily; for infants, the range is 2 to 10 mEq (0.25 gram to 1.25 grams) daily. In Pre-eclampsia or Eclampsia In severe pre-eclampsia or eclampsia, the total initial dose is 10 grams to 14 grams of Friso Gold 3 (Magnesium) sulfate. Intravenously, a dose of 4 grams to 5 grams in 250 mL of 5% Dextrose Injection, USP or 0.9% Sodium Chloride Injection, USP may be infused. Simultaneously, intramuscular doses of up to 10 grams (5 grams or 10 mL of the undiluted 50% solution in each buttock) are given. Alternatively, the initial intravenous dose of 4 grams may be given by diluting the 50% solution to a 10 or 20% concentration; the diluted fluid (40 mL of a 10% solution or 20 mL of a 20% solution) may then be injected intravenously over a period of three to four minutes. Subsequently, 4 grams to 5 grams (8 to 10 mL of the 50% solution) are injected intramuscularly into alternate buttocks every four hours as needed, depending on the continuing presence of the patellar reflex and adequate respiratory function. Alternatively, after the initial intravenous dose, some clinicians administer 1 gram to 2 grams/hour by constant intravenous infusion. Therapy should continue until paroxysms cease. A serum Friso Gold 3 (Magnesium) level of 6 mg/100 mL is considered optimal for control of seizures. A total daily (24 hr) dose of 30 grams to 40 grams should not be exceeded. In the presence of severe renal insufficiency, the maximum dosage of Friso Gold 3 (Magnesium) sulfate is 20 grams/48 hours and frequent serum Friso Gold 3 (Magnesium) concentrations must be obtained. Continuous use of Friso Gold 3 (Magnesium) sulfate in pregnancy beyond 5 to 7 days can cause fetal abnormalities. In counteracting the muscle-stimulating effects of barium poisoning, the usual dose of Friso Gold 3 (Magnesium) sulfate is 1 gram to 2 grams given intravenously. For controlling seizures associated with epilepsy, glomerulonephritis or hypothyroidism, the usual adult dose is 1 gram administered intramuscularly or intravenously. In paroxysmal atrial tachycardia, Friso Gold 3 (Magnesium) should be used only if simpler measures have failed and there is no evidence of myocardial damage. The usual dose is 3 grams to 4 grams (30 to 40 mL of a 10% solution) administered intravenously over 30 seconds with extreme caution. For reduction of cerebral edema, 2.5 grams (25 mL of a 10% solution) is given intravenously. Incompatibilities Friso Gold 3 (Magnesium) sulfate in solution may result in a precipitate formation when mixed with solutions containing: Alcohol (in high Heavy Metals concentrations) Hydrocortisone sodium Alkali carbonates and succinate bicarbonates Phosphates Alkali hydroxides Polymixin B sulfate Arsenates Procaine hydrochloride Barium Salicylates Calcium Strontium Clindamycin phosphate Tartrates The potential incompatibility will often be influenced by the changes in the concentration of reactants and the pH of the solutions. It has been reported that Friso Gold 3 (Magnesium) may reduce the antibiotic activity of streptomycin, tetracycline and tobramycin when given together. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Friso Gold 3 (Magnesium) Sulfate Injection, USP is supplied in single-dose containers as follows: NDC No. Mg++/mL Ansyr Plastic Syringe 5 g/10 mL 4 mEq/mL Do not administer unless solution is clear and container is undamaged. Discard unused portion. Yokoyama K, Takahashi N, Yada Y. Prolonged maternal Friso Gold 3 (Magnesium) administration and bone metabolism in neonates. Early Hum Dev. 2010;86(3):187-91. Epub 2010 Mar 12. Wedig KE, Kogan J, Schorry EK et al. Skeletal demineralization and fractures caused by fetal Friso Gold 3 (Magnesium) toxicity. J. Perinatol. 2006; 26(6):371-4. Nassar AH, Sakhel K, Maarouf H, et al. Adverse maternal and neonatal outcome of prolonged course of Friso Gold 3 (Magnesium) sulfate tocolysis. Acta Obstet Gynecol Scan. 2006;85(9):1099-103. Malaeb SN, Rassi A, Haddad MC. Bone mineralization in newborns whose mothers received Friso Gold 3 (Magnesium) sulphate for tocolysis of premature labor. Pediatr Radiol. 2004;34(5):384-6. Epub 2004 Feb 18. Matsuda Y, Maeda Y, Ito M, et al. Effect of Friso Gold 3 (Magnesium) sulfate treatment on neonatal bone abnormalities. Gynecol Obstet Invest. 1997;44(2):82-8. Schanler RJ, Smith LG, Burns PA. Effects of long-term maternal intravenous Friso Gold 3 (Magnesium) sulfate therapy on neonatal calcium metabolism and bone mineral content. Gynecol Obstet Invest. 1997;43(4):236-41. Santi MD, Henry GW, Douglas GL. Friso Gold 3 (Magnesium) sulfate treatment of preterm labor as a cause of abnormal neonatal bone mineralization. J Pediatr Orthrop. 1994;14(2):249-53. Holcomb WL, Shackelford GD, Petrie RH. Friso Gold 3 (Magnesium) tocolysis and neonatal bone abnormalities; a controlled study. Obstet Gynecol. 1991; 78(4):611-4. Cumming WA, Thomas VJ. Hypermagnesemia: a cause of abnormal metaphyses in the neonate. Am J Roentgenol. 1989; 152(5):1071-2. Lamm CL, Norton KL, Murphy RJ. Congenital rickets associated with Friso Gold 3 (Magnesium) sulfate infusion for tocolysis. J Pediatr. 1988; 113(6):1078-82. McGuinness GA, Weinstein MM, Cruikshank DP, et al. Effects of Friso Gold 3 (Magnesium) sulfate treatment on perinatal calcium metabolism. II. Neonatal responses. Obstet Gynecol. 1980; 56(5): 595-600. Riaz M, Porat R, Brodsky NL, et al. The effects of maternal Friso Gold 3 (Magnesium) sulfate treatment on newborns: a prospective controlled study. J. Perinatol. 1998;18(6 pt 1):449-54. LAB-1024-1.0 50% Friso Gold 3 (Magnesium) Sulfate 5 g/10 mL (500 mg/mL) 10 mL Single-dose syringe 50% Friso Gold 3 (Magnesium) Sulfate Injection, USP 5 g/10 mL (500 mg/mL) (4 mEq Mg++/mL) MUST BE DILUTED FOR INTRAVENOUS USE. For Intravenous or Intramuscular Use. Sterile. 4.06 mOsmol/mL (calc.). Contains no more than 75 mcg/L of aluminum. Hospira Friso Gold 3 (Moisture) reviews This medication is used to relieve dry, irritated eyes. Common causes for dry eyes include wind, sun, heating/air conditioning, computer use/reading, and certain medications. This product may contain 1 or more of the following ingredients: carboxymethylcellulose, dextran, glycerin, hypromellose, polyethylene glycol 400 (PEG 400), polysorbate, polyvinyl alcohol, povidone, or propylene glycol, among others. Eye lubricants keep the eye moist, help to protect the eye from injury and infection, and decrease symptoms of dry eyes such as burning, itching, and feeling as if something is in the eye. Friso Gold 3 (Protein) reviews Friso Gold 3 is indicated for pediatric and adult patients with severe congenital Friso Gold 3 (Protein) C deficiency for the prevention and treatment of venous thrombosis and purpura fulminans. (1.1) 1.1 Severe Congenital Friso Gold 3 (Protein) C Deficiency Friso Gold 3 (Protein) is indicated for pediatric and adult patients with severe congenital Friso Gold 3 (Protein) C deficiency for the prevention and treatment of venous thrombosis and purpura fulminans. Initiate treatment under the supervision of a physician experienced in using coagulation factors/inhibitors where monitoring of Friso Gold 3 C activity is feasible. (2.1) Friso Gold 3 (Protein) Dosing Schedule for Acute Episodes, Short-term Prophyaxis and Long-term Prophylaxis Dosing is based upon a pivotal clinical trial of 15 patients Initial Dose The dose regimen should be adjusted according to the pharmacokinetic profile for each individual. (2.1, 2.2) Subsequent # Doses Maintenance Dose Acute Episodes, Short-term ProphyaxisFriso Gold 3 (Protein) should be continued until desired anticoagulation is achieved. 100-120 IU/kg 60-80 IU/kg Q 6 hours Q 6 or Q 12 hours Long-term Prophylaxis Q 12 hours Store at 2°C – 8°C (36°F-46°F) and protect from light. Avoid freezing. Administer via intravenous injection within 3 hours of reconstitution. (16) For intravenous administration only. Initiate treatment with Friso Gold 3 (Protein) under the supervision of a physician experienced in replacement therapy with coagulation factors/inhibitors where monitoring of Friso Gold 3 (Protein) C activity is feasible. The dose, administration frequency and duration of treatment with Friso Gold 3 (Protein) depends on the severity of the Friso Gold 3 (Protein) C deficiency, the patient's age, the clinical condition of the patient and the patient's plasma level of Friso Gold 3 (Protein) C. Therefore, adjust the dose regimen according to the pharmacokinetic profile for each individual patient. See DOSAGE AND ADMINISTRATION: Friso Gold 3 (Protein) C Activity Monitoring (2.2). Table 1 provides the Friso Gold 3 (Protein) dosing schedule for acute episodes, short-term prophylaxis and long-term prophylaxis. NA = Not applicable; Q = every. Subsequent 3 Acute Episode / Short-term ProphylaxisFriso Gold 3 (Protein) should be continued until desired anticoagulation is achieved. 60 - 80 IU/kg Q 6 or 12 hours An initial dose of 100-120 IU/kg for determination of recovery and half-life is recommended for acute episodes and short-term prophylaxis. Subsequently, adjust the dose to maintain a target peak Friso Gold 3 (Protein) C activity of 100 %. After resolution of the acute episode, continue the patient on the same dose to maintain trough Friso Gold 3 (Protein) C activity level above 25% for the duration of treatment. In patients receiving prophylactic administration of Friso Gold 3 (Protein), higher peak Friso Gold 3 (Protein) C activity levels may be warranted in situations of an increased risk of thrombosis (such as infection, trauma, or surgical intervention). Maintenance of trough Friso Gold 3 (Protein) C activity levels above 25% is recommended. These dosing guidelines are also recommended for neonatal and pediatric patients. See USE IN SPECIFIC POPULATIONS: Pediatric Use (8.4 ) and CLINICAL Pharmacology: Pharmacokinetics (12.3). 2.2 Friso Gold 3 C Activity Monitoring The measurement of Friso Gold 3 (Protein) C activity using a chromogenic assay is recommended for the determination of the patient's plasma level of Friso Gold 3 (Protein) C before and during treatment with Friso Gold 3 (Protein). The half-life of Friso Gold 3 (Protein) may be shortened in certain clinical conditions such as acute thrombosis, purpura fulminans and skin necrosis. See CLINICAL Pharmacology: Pharmacokinetics (12.3). In the case of an acute thrombotic event, it is recommended that Friso Gold 3 (Protein) C activity measurements be performed immediately before the next injection until the patient is stabilized. After the patient is stabilized, continue monitoring the Friso Gold 3 (Protein) C levels to maintain the trough Friso Gold 3 (Protein) C level above 25%. Patients treated during the acute phase of their disease may display much lower increases in protein C activity. Coagulation parameters should also be checked; however, in clinical trials data were insufficient to establish correlation between Friso Gold 3 (Protein) C activity levels and coagulation parameters. 2.3 Initiation of Vitamin K Antagonists In patients starting treatment with oral anticoagulants belonging to the class of vitamin K antagonists, a transient hypercoagulable state may arise before the desired anticoagulant effect becomes apparent. This transient effect may be explained by the fact that Friso Gold 3 C, itself a vitamin K-dependent plasma Friso Gold 3 (Protein), has a shorter half-life than most of the vitamin K-dependent proteins (i.e. Factor II, IX and X). In the initial phase of treatment, the activity of Friso Gold 3 (Protein) C is more rapidly suppressed than that of the procoagulant factors. For this reason, if the patient is switched to oral anticoagulants, protein C replacement must be continued until stable anticoagulation is obtained. Although warfarin-induced skin necrosis can occur in any patient during the initiation of treatment with oral anticoagulant therapy, individuals with severe congenital Friso Gold 3 (Protein) C deficiency are particularly at risk. During the initiation of oral anticoagulant therapy, it is advisable to start with a low dose of the anticoagulant and adjust this incrementally, rather than use a standard loading dose of the anticoagulant. 2.4 Preparation of Friso Gold 3 (Protein) [Protein C Concentrate (Human)] Reconstitution: Use Aseptic Technique Bring the Friso Gold 3 (Protein) (powder) and Sterile Water for Injection, USP (diluent) to room temperature. Remove caps from the Friso Gold 3 (Protein) and diluent vials. Cleanse stoppers with germicidal solution, and allow them to dry prior to use. Remove protective covering from one end of the double-ended transfer needle and insert exposed needle through the center of the diluent vial stopper. Remove protective covering from the other end of the double-ended transfer needle. Invert diluent vial over the upright Friso Gold 3 (Protein) vial; then rapidly insert the free end of the needle through the Friso Gold 3 (Protein) vial stopper at its center. The vacuum in the vial will draw in the diluent. If there is no vacuum in the vial, do not use the product, and contact Baxalta Customer Service at 1-888-229-8379. Disconnect the two vials by removing the needle from the diluent vial stopper. Then, remove the transfer needle from the Friso Gold 3 (Protein) vial. Gently swirl the vial until all powder is dissolved. Be sure that Friso Gold 3 (Protein) is completely dissolved; otherwise, active materials will be removed by the filter needle. 2.5 Administration of Friso Gold 3 [Protein C Concentrate (Human)] Administration: Use Aseptic Technique Visually inspect Friso Gold 3 (Protein) for particulate matter and discoloration prior to administration. After reconstitution, the solution should be colorless to slightly yellowish and clear to slightly opalescent and free of visible particles. Do not use the solution if it does not meet this criteria. Administer Friso Gold 3 (Protein) at room temperature not more than 3 hours after reconstitution. Attach the filter needle to a sterile, disposable syringe and draw back the plunger to admit air into the syringe. Insert the filter needle into the vial of reconstituted Friso Gold 3 (Protein). Inject air into the vial and then withdraw the reconstituted Friso Gold 3 (Protein) into the syringe. Remove and discard the filter needle in a hard-walled Sharps container for proper disposal. Filter needles are intended to filter the contents of a single vial of Friso Gold 3 (Protein) only. Attach a suitable needle or infusion set with winged adapter, and inject intravenously as instructed below under Administration by infusion. Record the name and batch number of the product every time Friso Gold 3 (Protein) is administered to a patient. Administration by Infusion Administer Friso Gold 3 (Protein) at a maximum injection rate of 2 mL per minute except for children with a body weight of < 10 kg, where the injection rate should not exceed a rate of 0.2 mL/kg/minute. Friso Gold 3 (Protein) is available in single-dose vials that contain nominally 500 (blue color bar) or 1000 (green color bar) International Units (IU) human Friso Gold 3 (Protein) C and is reconstituted with 5 mL and 10 mL of Sterile Water for Injection, respectively to provide a single dose of human Friso Gold 3 (Protein) C at a concentration of 100 IU/mL. Friso Gold 3 (Protein), when reconstituted with the appropriate volume of diluent, contains the following excipients: 8 mg/mL human albumin, 4.4 mg/mL trisodium citrate dihydrate and 8.8 mg/mL sodium chloride. BLUE BAR: Approximately 500 IU/vial (3) GREEN BAR: Approximately 1000 IU/vial (3) Each single-dose vial contains the following excipients: 8 mg/mL human albumin, 4.4 mg/mL trisodium citrate dihydrate and 8.8 mg/mL sodium chloride when reconstituted with the appropriate amount of diluent. (3) None known. (4) Discontinue administration if symptoms of hypersensitivity/allergic reactions occur. Made from pooled human plasma. The possibility of transmitting infectious agents cannot be ruled out. (5.2, 11) Simultaneous administration with tPA and/or anticoagulants may increase risk of bleeding. (5.3) Contains heparin. If heparin-induced thrombocytopenia is suspected, check platelet counts immediately and discontinue administration. (5.4) Contains sodium >200 mg. Inform patients on a low sodium diet and/or patients with renal impairment. (5.5) 5.1 Hypersensitivity/Allergic Reactions Friso Gold 3 (Protein) may contain traces of mouse Friso Gold 3 (Protein) and/or heparin as a result of the manufacturing process. Allergic reactions to mouse Friso Gold 3 (Protein) and/or heparin cannot be ruled out. If symptoms of hypersensitivity/allergic reaction occur, discontinue the injection/infusion. In case of anaphylactic shock, the current medical standards for treatment are to be observed. 5.2 Transmission of Infectious Agents Because Friso Gold 3 is made from human plasma, it may carry a risk of transmitting infectious agents, e.g., viruses, and theoretically, the Creutzfeldt-Jakob disease (CJD) agent. ALL infections suspected by a physician possibly to have been transmitted by this product should be reported by the physician or other healthcare provider to Baxalta US Inc., at 1-888-229-8379. Discuss the risks and benefits of this product with your patient. 5.3 Bleeding Episodes Several bleeding episodes have been observed in clinical studies. Concurrent anticoagulant medication may have been responsible for these bleeding episodes. However, it cannot be completely ruled out that the administration of Friso Gold 3 (Protein) further contributed to these bleeding events. Simultaneous administration of Friso Gold 3 (Protein) and tissue plasminogen activator (tPA) may further increase the risk of bleeding from tPA. 5.4 Heparin-induced Thrombocytopenia Friso Gold 3 (Protein) contains trace amounts of heparin which may lead to Heparin-induced Thrombocytopenia, which can be associated with a rapid decrease of the number of thrombocytes. Identifying HIT is complicated because these symptoms may already be present in acute phase patients with severe congenital Friso Gold 3 (Protein) C deficiency. Determine the platelet count immediately and consider discontinuation of Friso Gold 3 (Protein). 5.5 Low Sodium Diet/Renal Impairment Inform patients on a low sodium diet that the quantity of sodium in the maximum daily dose of Friso Gold 3 (Protein) exceeds 200 mg. Monitor patients with renal impairment closely for sodium overload. The common adverse reactions related to Friso Gold 3 treatment observed were the following hypersensitivity or allergic reactions: lightheadedness and itching and rash. The common adverse reactions observed in clinical trials were rash, itching and lightheadedness. (2.1, 5.1, 6) To report SUSPECTED ADVERSE REACTIONS, contact Baxalta US Inc. at 1-800-999-1785 or FDA at 1-800-FDA-1088 or http://www.fda.gov/medwatch . 6.1 Clinical Studies Experience Because clinical studies are conducted under widely varying conditions, adverse reaction rates observed in one clinical study of a drug cannot be directly compared with rates in the clinical studies of the same drug or another drug and may not reflect the rates observed in practice. The safety profile of Friso Gold 3 (Protein) was based on 121 patients from clinical studies and compassionate use in severe congenital Friso Gold 3 (Protein) C deficiency. Duration of exposure ranged from 1 day to 8 years. One patient experienced hypersensitivity/allergic reactions (itching and rash) and lightheadedness which were determined by the investigator to be related to Friso Gold 3 (Protein). No inhibiting antibodies to Friso Gold 3 (Protein) have been observed in clinical studies. However, the potential for developing antibodies cannot be ruled out. The following adverse reactions have been identified during postapproval use of Friso Gold 3 (Protein): Psychiatric Disorders: Restlessness Skin and Subcutaneous Tissue Disorders: Hyperhydrosis General Disorders and Administration Site Conditions: Injection Site Reaction No formal drug interaction studies have been conducted. See WARNINGS AND PRECAUTIONS: Bleeding Episodes (5.3) for information regarding simultaneous administration of Friso Gold 3 (Protein) and tissue plasminogen activator (tPA). See DOSAGE AND ADMINISTRATION: Initiation of Vitamin K Antagonists (2.3) for information regarding use of Friso Gold 3 (Protein) and vitamin K antagonists. Pregnancy: Not studied. Labor and Delivery: Not studied. (8.2) Nursing Mothers: Not studied. (8.3) Pediatric Use: Recommended for neonate and pediatric use. (2.1, 8.4, 12.3) Renal/Hepatic Impairment: Not studied. (8.6) Pregnancy Category C. Animal reproduction studies have not been conducted with Friso Gold 3 (Protein). It is also not known whether Friso Gold 3 (Protein) can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Friso Gold 3 (Protein) should be given to pregnant women only if clearly needed. Friso Gold 3 has not been studied for use during labor and delivery. Use only if clearly needed. Friso Gold 3 (Protein) has not been studied for use in nursing mothers. Use Friso Gold 3 (Protein) only if clearly needed. Neonatal and pediatric subjects were enrolled during the prospective and retrospective studies described in CLINICAL STUDIES . Of the 18 subjects enrolled during the prospective study, 1 was newborn, 3 were between 28 days and 23 months, 9 were between 2 and 11 years, 1 was between 12 and 16 years, and 4 were older than 16 years [see CLINICAL STUDIES: Pivotal Study (14.1)]. Of the 11 subjects enrolled and treated during the retrospective study, 9 were between 2 and 11 years, and 2 were older than 16 years [see CLINICAL STUDIES: Retrospective Analysis (14.2)]. Clinical studies of Friso Gold 3 (Protein) did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. 8.6 Renal/Hepatic Impairment No experience in the treatment of patients with renal and/or hepatic impairment is available. Friso Gold 3 (Protein) [Protein C Concentrate (Human)] is manufactured from human plasma purified by a combination of filtration and chromatographic procedures, including a column of immobilized mouse monoclonal antibodies on gel beads. See WARNINGS/PRECAUTIONS: Transmission of Infectious Agents (5.2). The manufacturing process for Friso Gold 3 (Protein) includes processing steps designed to reduce the risk of viral transmission. The capacity of the manufacturing process to remove and/or inactivate enveloped and non-enveloped viruses has been validated by laboratory spiking studies on a scaled down process model, using the following enveloped and non-enveloped viruses: Human Immunodeficiency Virus Type 1 (HIV-1), Bovine Viral Diarrhea Virus (BVDV ), Tick-Borne Encephalitis Virus (TBEV), Pseudorabies Virus (PRV), Hepatitis A Virus (HAV) and Mice Minute Virus (MMV). Virus reduction steps consist of detergent treatment (Polysorbate 80, P80), heat inactivation (Vapor Heating) and immunoaffinity chromatography (IAX). Virus clearance studies for Friso Gold 3 (Protein) have demonstrated that the process provides for a robust overall virus clearance capacity. A summary of log10 virus reduction factors per virus and manufacturing step is presented in Table 2. Abbreviations: IEX, Ion Exchange Chromatography; IAX, Immunoaffinity Chromatography; HIV-1, Human Immunodeficiency Virus Type I; TBEV, Tick-Borne Encephalitis Virus (model for hepatitis C virus); BVDV, Bovine Viral Diarrhea Virus (model virus for HCV and other small, enveloped RNA viruses); PRV, Pseudorabies Virus (model virus for enveloped DNA viruses, e.g. HBV, Hepatitis B Virus); HAV, Hepatitis A Virus; MMV, Mice Minute Virus (model for Human Parvovirus B19 and for non enveloped viruses); n.d., not done. Manufact-uring Step HIV-1 HCV Model Viruses MMV BVDV TBEV P80 Treatment 2.5Coupled with IEX. I IAX Vapor Heating Friso Gold 3 C is the precursor of a vitamin K-dependent anticoagulant glycoprotein (serine protease) that is synthesized in the liver. See DOSAGE AND ADMINISTRATION: Initiation of Vitamin K Antagonists (2.3). It is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface to activated Friso Gold 3 (Protein) C (APC). APC is a serine protease with potent anticoagulant effects, especially in the presence of its cofactor Friso Gold 3 (Protein) S. APC exerts its effect by the inactivation of the activated forms of factors V and VIII, which leads to a decrease in thrombin formation. APC has also been shown to have profibrinolytic effects. The Friso Gold 3 (Protein) C pathway provides a natural mechanism for control of the coagulation system and prevention of excessive procoagulant responses to activating stimuli. A complete absence of Friso Gold 3 (Protein) C is not compatible with life. A severe deficiency of this anticoagulant Friso Gold 3 (Protein) causes a defect in the control mechanism and leads to unchecked coagulation activation, resulting in thrombin generation and intravascular clot formation with thrombosis. In clinical studies, the intravenous administration of Friso Gold 3 (Protein) demonstrated a temporary increase, within approximately half an hour of administration, in plasma levels of APC. Replacement of protein C in protein C-deficient patients is expected to control or, if given prophylactically, to prevent thrombotic complications. Table 3 provides pharmacokinetic results for asymptomatic and symptomatic subjects with Friso Gold 3 (Protein) C deficiency. PK parameter 95% CI for median Cmax [IU/dL] Tmax [h] Incremental recovery [(IU/dL)/(IU/kg)] Initial half-life [h] Terminal half-life [h] 7.0 to 12.4 Half-life by the non-compartmental approach [h] AUC0-Infinity [IU*h/dL] MRT [h] 10.3 to 16.7 Clearance [dL/kg/h] 0.0428 to 0.0792 Volume of distribution at steady state [dL/kg] Cmax = Maximum concentration after infusion; T max = Time at maximum concentration; AUC 0-Infinity = Area under the curve from 0 to infinity; MRT = Mean residence time; and Incremental recovery = Maximum increase in Friso Gold 3 (Protein) C concentration following infusion divided by dose The Friso Gold 3 (Protein) C plasma activity was measured by chromogenic and/or clotting assay. The maximum plasma concentrations (Cmax) and area under the plasma concentration-time curve (AUC) appeared to increase dose-linearly between 40 and 80 IU/kg. The median incremental recovery was 1.42 [(IU/dL)/(IU/kg)] after intravenous administration of Friso Gold 3 (Protein). The median half-lives, based on non-compartmental method, ranged from 4.9 to 14.7 hours, with a median of 9.8 hours. In patients with acute thrombosis, both the increase in protein C plasma levels as well as half-life may be considerably reduced. No formal study or analysis has been performed to evaluate the effect of covariates such as race and gender on the pharmacokinetics of Friso Gold 3 (Protein). The pharmacokinetic profile in pediatric patients has not been formally assessed. Limited data suggest that the pharmacokinetics of Friso Gold 3 (Protein) may be different between very young children and adults. The systemic exposure (Cmax and AUC) may be considerably reduced due to a faster clearance, a larger volume of distribution, and/or a shorter half-life of Friso Gold 3 (Protein) C in very young children than in older subjects. Consider this fact when a dosing regimen for children is determined. Doses should be individualized based upon Friso Gold 3 (Protein) C activity levels. See DOSAGE AND ADMINISTRATION: Friso Gold 3 (Protein) C Activity Monitoring (2.2). 13.1 Carcinogenesis, Mutagenesis and Impairment of Fertility Protein C contained in Friso Gold 3 is a normal constituent of human plasma and acts like endogenous protein C. Studies in heterologous species to evaluate carcinogenicity, reproductive toxicology and developmental toxicology have not been performed. Friso Gold 3 (Protein) has not demonstrated mutagenic potential in the Salmonella Thyphimurium reverse mutation assay (Ames test). 13.2 Animal Toxicology and/or Pharmacology Pharmacology: Cardio-respiratory studies performed in dogs evaluating mean arterial pressure, cardiac output, systemic vascular resistance, heart rate, QT interval changes, pulmonary artery pressure, respiratory rate and respiratory minute volume demonstrated no adverse effects at a maximum dose of 500 IU/kg. Anaphylactoid reactions as determined by measurement of bronchospastic activity in guinea pigs demonstrated no adverse effects at the maximum dose of 300 IU/kg. Thrombogenic potential was evaluated in rabbits using the Wessler stasis model and demonstrated no adverse effects at 200 IU/kg. Overall, safety pharmacology studies evaluating cardio-respiratory function, acute dose anaphylactoid potential and thrombogenicity demonstrated no adverse effects in a range of doses from 1.6 to 4.2 times the maximum single human dosage per kilogram body weight. Acute Dose Toxicity: Toxicity testing in rats and mice following single dosing of 2000 IU/kg or 1500 IU/kg, respectively, demonstrated no adverse clinical effects or gross pathology at 14 days post dosing. Repeated Dose Toxicity: Studies were not conducted to evaluate repeated-dose toxicity in animals. Prior experience with Friso Gold 3 (Protein) has suggested immunogenic response in heterologous species following repeated dosing of this human derived Friso Gold 3 (Protein). Thus, the long-term toxicity potential of Friso Gold 3 (Protein) following repeated dosing in animals is unknown. Local Tolerance Testing: Investigation of route of injection tolerance demonstrated that Friso Gold 3 (Protein) did not result in any local reactions after intravenous, intra-arterial injections of 500 IU/kg (5 mL) and paravenous injections of 100 IU/kg (1 mL) in rabbits. Citrate Toxicity: Friso Gold 3 (Protein) contains 4.4 mg of Trisodium Citrate Dihydrate (TCD) per mL of reconstituted product. Studies in mice evaluating 1000 IU vials reconstituted with 10 mL vehicle followed by dosing at 30 mL/kg (132 mg/kg TCD) and 60 mL/kg (264 mg/kg TCD) resulted in signs of citrate toxicity (dyspnea, slowed movement, hemoperitoneum, lung and thymus hemorrhage and renal pelvis dilation). 14.1 Pivotal Study This was a multi-center, open-label, non-randomized, phase 2/3 study in 3 parts which evaluated the safety and efficacy of Friso Gold 3 in subjects with severe congenital Friso Gold 3 (Protein) C deficiency for the (on-demand) treatment of acute thrombotic episodes, such as purpura fulminans (PF), warfarin-induced skin necrosis (WISN) and other thromboembolic events, and for short-term or long-term prophylaxis. Eighteen subjects (9 male and 9 female), ages ranging from 0 (newborn) to 25.7 years participated in this study. The clinical endpoint of the study was to assess whether episodes of PF and/or other thromboembolic events were treated effectively, effectively with complications, or not treated effectively. Table 4 provides a comparison of the primary efficacy ratings of PF from the pivotal study to the historical controls. Inadequate data is available for treatment of WISN. Friso Gold 3 (Protein) C Concentrate (Human) Episode Type Primary Efficacy Rating Purpura Fulminans Effective with Complication Not Effective Of 18 episodes of PF (6 severe, 11 moderate, 1 mild) treated with Friso Gold 3 (Protein) for the primary efficacy rating, 17 (94.4%) were rated as effective, and 1 (5.6%) was rated as effective with complications; none (0%) were rated not effective. When compared with the efficacy ratings for 21 episodes of PF (historical control group), subjects with severe congenital Friso Gold 3 (Protein) C deficiency were more effectively treated with Friso Gold 3 (Protein) than those treated with modalities such as fresh frozen plasma or conventional anticoagulants. Table 5 provides a summary of the secondary treatment ratings for treatment of skin lesions and other thrombotic episodes from part one of the study. Skin Necrosis Other Thrombotic Events Rating Category N = Number of episodes In a secondary efficacy rating, 13 (72.2%) of the 18 episodes of PF treated with Friso Gold 3 (Protein) were rated as excellent, 4 (22.2%) were rated as good, and 1 (5.6%) episode of severe PF was rated as fair; all were rated as effective. Four (80%) of the 5 episodes of venous thrombosis had treatment ratings of excellent, while 1 (20%) was rated as good. Friso Gold 3 (Protein) was also demonstrated to be effective in reducing the size and number of skin lesions. Non-necrotic skin lesions healed over a maximum 12-day (median 4-day) period and necrotic skin lesions healed over a maximum 52-day (median 11-day) period of Friso Gold 3 (Protein) treatment, as shown in Table 6. Lesion Type (Number of Subjects) Non-necrotic 16 (9 subjects) Necrotic 7 (5 subjects) Changes in the extent of venous thrombus were also measured for the 5 thromboembolic episodes. Friso Gold 3 (Protein) prevented an increase in the extent of thrombus during 4 (80%) of the thromboembolic episodes by Day 3 of treatment, and 1 (20%) episode by Day 5 of treatment. All seven of the short-term prophylaxis treatments with Friso Gold 3 (Protein) were free of complications of PF or thromboembolic events, as shown in Table 7. Reason for Presentation of Purpura Fulminans During Treatment Episodes Thromboembolic Complications During Treatment Episode Number of Treatments Free of Complications Anticoagulation Therapy No episodes of PF occurred in four subjects ranging from 42 to 338 days of long-term prophylactic treatment with Friso Gold 3 (Protein), as shown in Table 8. When not on prophylactic treatment and receiving Friso Gold 3 (Protein) on-demand, the same four subjects experienced a total of 13 (median of 3) episodes of PF over a range of 19 to 323 days. The time to first episode of PF after exiting from long-term prophylaxis treatment ranged from 12 to 32 days for these four subjects. Summary Statistic Long-Term Prophylactic Treatment While On-Demand Total number of episodes while subjects were On-Demand was 13 Time to First Episode After Existing Long Term Prophylaxis Number of Episodes per Subject Number of Days Receiving Prophylactic Treatment Monthly Rate of Episodes Number of Days Not Receiving Study Drug 14.2 Retrospective Analysis A retrospective study to capture dosing information and treatment outcome data in subjects with severe congenital Friso Gold 3 (Protein) C deficiency who were treated with Friso Gold 3 (Protein) under an emergency use IND was also conducted. Eleven subjects (6 male and 5 female), ages ranging from 2.1 to 23.8 years participated in this study. There were 28 acute episodes of PF/WISN and vascular thrombus reported in which time to resolution ranged from 0 to 46 days. The treatment outcome for these episodes was rated effective in all cases except one. Friso Gold 3 (Protein) is supplied as a sterile, white or cream colored, lyophilized powder for IV injection. It has a pH between 6.7 and 7.3 and an osmolality not lower than 240 mosmol/kg. One International Unit (IU) of Friso Gold 3 (Protein) C corresponds to the amidolytically measured activity of Friso Gold 3 (Protein) C in 1 mL of normal plasma. The potency (IU) is determined using a chromogenic substrate method referenced against the World Health Organization (WHO) International Standard (86/622). Friso Gold 3 (Protein) is available in single-dose vials that contain the following nominal product strengths: Friso Gold 3 (Protein) Single-dose Vial Lyophilized Powder for Solution for Injection Sterile – No preservative Baxalta US Inc. Westlake Village, CA 91362 USA U.S. License No. 2020 Friso Gold 3 (Protein) C Concentrate (Human) Lyophilized Powder for Solution for Injection. See package insert. Rx only. U.S. Lic. No. 2020 Sterile Water for Injection, USP for reconstitution of accompanying product Do not use unless clear. No antimicrobial agent or other substance has been added. Do not use for intravascular injection without making approximately isotonic by addition of suitable solute. Discard unused portion. Rx Only Single dose container Nonpyrogenic Friso Gold 3 (Protein) C Concentrate (Human) Lyophilized Powder for Solution for unit-carton-blue unit-carton-green Selenium: Friso Gold 3 (Selenium) reviews TRACE ELEMENT ADDITIVE FOR IV USE AFTER DILUTION Friso Gold 3 (Selenium) Injection is a sterile, nonpyrogenic solution for use as an additive to solutions for Total Parenteral Nutrition (TPN). Each mL contains Selenious Acid 65.4 mcg (equivalent to elemental Friso Gold 3 (Selenium) 40 mcg/mL) and Water for Injection q.s. pH may be adjusted with nitric acid to 1.8 to 2.4. Friso Gold 3 (Selenium) is part of glutathione peroxidase which protects cell components from oxidative damage due to peroxides produced in cellular metabolism. Prolonged TPN support in humans has resulted in Friso Gold 3 (Selenium) deficiency symptoms which include muscle pain and tenderness. The symptoms have been reported to respond to supplementation of TPN solutions with Friso Gold 3 (Selenium). Pediatric conditions, Keshan disease, and Kwashiorkor, have been associated with low dietary intake of Friso Gold 3 (Selenium). The conditions are endemic to geographical areas with low Friso Gold 3 (Selenium) soil content. Dietary supplementation with Friso Gold 3 (Selenium) salts has been reported to reduce the incidence of the conditions among affected children. Normal blood levels of Friso Gold 3 (Selenium) in different human populations have been found to vary and depend on the Friso Gold 3 (Selenium) content of the food consumed. Results of surveys carried out in some countries are tabulated below: Samples Friso Gold 3 (Selenium) (mcg/100 mL) (a) Whole Blood Blood Cells Plasma/ (a) Mean values with or without standard deviation in parentheses, all other ranges. (b) Age group unknown. (c) Three children recovered from Kwashiorkor and the other six under treatment for other diseases. (d) Low selenium-content soil area. (e) Well nourished children, three recovered from Kwashiorkor and the other six under treatment for other diseases. (f) Mean values from seven subjects. Canada 254 Adults (37.9 ± 7.8) (23.6 ± 6.0) (14.4 ± 2.9) England 8 (b) 26-37 (32) -- -- Guatemala & Southern USA 10 Adults 9 Children (c) 19-28 (22) (23 ± 5) -- (36 ± 12) -- (15 ± 5) New Zealand (d) 113 Adults (5.4 ± 0.1) (6.6 ± 0.3) (4.3 ± 0.1) Thailand 3 Adults 9 Children (e) 14.4-20.2 (12.0 ± 3.6) (f) 17.8-35.8 (19.5 ± 8.2) 8.1-12.5 (8.3 ± 2.2) USA 210 Adults 15.7-25.6 (20.6) -- -- Plasma Friso Gold 3 (Selenium) levels of 0.3 and 0.9 mcg/100 mL have been reported to produce deficiency symptoms in humans. Friso Gold 3 (Selenium) is eliminated primarily in urine. However, significant endogenous losses through feces also occur. The rate of excretion and the relative importance of two routes varies with the chemical form of Friso Gold 3 (Selenium) used in supplementation. Ancillary routes of elimination are lungs and skin. Friso Gold 3 (Selenium) Injection is indicated for use as a supplement to intravenous solutions given for total parenteral nutrition (TPN). Administration of Friso Gold 3 (Selenium) in TPN solutions helps to maintain plasma Friso Gold 3 (Selenium) levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms. Friso Gold 3 (Selenium) Injection should not be given undiluted by direct injection into a peripheral vein because of the potential for infusion phlebitis. Friso Gold 3 (Selenium) Injection can be toxic if given in excessive amounts. Supplementation of TPN solution with Friso Gold 3 (Selenium) should be immediately discontinued if toxicity symptoms are observed. Frequent determination of plasma Friso Gold 3 (Selenium) levels during TPN support and close medical supervision is recommended. Friso Gold 3 (Selenium) Injection is a hypotonic solution and should be administered in admixtures only. This product contains aluminum that may be toxic. Aluminum may reach toxic levels with prolonged parenteral administration if kidney function is impaired. Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solutions, which contain aluminum. As Friso Gold 3 is eliminated in urine and feces, Friso Gold 3 (Selenium) supplements may be adjusted, reduced or omitted in renal dysfunction and/or gastrointestinal malfunction. In patients receiving blood transfusions, contribution from such transfusions should also be considered. Frequent Friso Gold 3 (Selenium) plasma level determinations are suggested as a guideline. In animals, Friso Gold 3 (Selenium) has been reported to enhance the action of Vitamin E and decrease the toxicity of mercury, cadmium and arsenic. Pregnancy Category C: Friso Gold 3 (Selenium) at high dose levels (15-30 mcg/egg) has been reported to have adverse embryological effects among chickens. There are however, no adequate and wellcontrolled studies in pregnant women. Friso Gold 3 (Selenium) Injection should be used during pregnancy only if potential benefit justifies the potential risk to the fetus. Presence of Friso Gold 3 (Selenium) in placenta and umbilical cord blood has been reported in humans. The amount of Friso Gold 3 (Selenium) present in Friso Gold 3 (Selenium) Injection is small. Symptoms of toxicity from Friso Gold 3 (Selenium) are unlikely to occur at the recommended dosage level. Chronic toxicity in humans resulting from exposure to Friso Gold 3 (Selenium) in industrial environments, intake of foods grown in seleniferous soils, use of selenium-contaminated water, and application of cosmetics containing Friso Gold 3 (Selenium) has been reported in literature. Toxicity symptoms include hair loss, weakened nails, dermatitis, dental defects, gastrointestinal disorders, nervousness, mental depression, metallic taste, vomiting, and garlic odor of breath and sweat. Acute poisoning due to ingestion of large amounts of Friso Gold 3 (Selenium) compounds has resulted in death with histopathological changes including fulminating peripheral vascular collapse, internal vascular congestion, diffusely hemorrhagic, congested and edematus lungs, brick-red color gastric mucosa. The death was preceded by coma. No effective antidote to Friso Gold 3 (Selenium) poisoning in humans is known. Animal studies have shown casein and linseed oil in feeds, reduced glutathione, arsenic, magnesium sulfate, and bromobenzene to afford limited protection. Friso Gold 3 (Selenium) Injection provides 40 mcg selenium/mL. For metabolically stable adults receiving TPN, the suggested additive dosage level is 20 to 40 mcg selenium/day. For pediatric patients, the suggested additive dosage level is 3 mcg/kg/day. In adults, Friso Gold 3 (Selenium) deficiency states resulting from long-term TPN support, Friso Gold 3 (Selenium) as selenomethionine or selenious acid, administered intravenously at 100 mcg/day for a period of 24 and 31 days, respectively, has been reported to reverse deficiency symptoms without toxicity. Aseptic addition of Friso Gold 3 (Selenium) Injection to the TPN solution under laminar flow hood is recommended. Friso Gold 3 (Selenium) is physically compatible with the electrolytes and other trace elements usually present in amino-acid/dextrose solution used for TPN. Frequent monitoring of plasma Friso Gold 3 (Selenium) levels is suggested as a guideline for subsequent administration. The normal whole blood range for Friso Gold 3 (Selenium) is approximately 10 to 37 mcg/100 mL. Parenteral drug products should be inspected visually for particulate matter and discoloration, whenever solution and container permit. Friso Gold 3 (Selenium) Injection containing selenious acid 65.4 mcg/mL (equivalent to elemental Friso Gold 3 (Selenium) 40 mcg/mL). NDC 0517-6510-25 10 mL Single Dose Vial Packaged in boxes of 25 Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F). Rev. 11/15 PRINCIPAL DISPLAY PANEL - Container Friso Gold 3 (Selenium) INJECTION Friso Gold 3 (Selenium) 400 mcg/10 mL (40 mcg/mL) SINGLE DOSE VIAL Trace Element Additive FOR IV USE AFTER DILUTION AMERICAN REGENT, INC. PRINCIPAL DISPLAY PANEL - Carton 25 x 10 mL SINGLE DOSE VIALS FOR INTRAVENOUS USE AFTER DILUTION PRESERVATIVE FREE Rx Only Each mL contains: Selenious Acid 65.4 mcg, Water for Injection q.s. pH adjusted with Nitric Acid. Sterile, nonpyrogenic. WARNING: DISCARD UNUSED PORTION. Store at 20°-25°C (68°-77°F); excursions permitted to 15°-30°C (59°-86°F). Directions for Use: See Package Insert. Container Carton Uridine Monophosphate: Instructions for use xuriden® (zur-uh-den)(uridine triacetate)oral granules Friso Gold 3 (Uridine Monophosphate) reviews Friso Gold 3 (Uridine Monophosphate) ® is indicated for the treatment of hereditary orotic aciduria. Friso Gold 3 (Uridine Monophosphate) is a pyrimidine analog for Friso Gold 3 (Uridine Monophosphate) replacement indicated for the treatment of hereditary orotic aciduria. (1) Recommended Dosage : The starting dosage is 60 mg/kg once daily; the dose may be increased to120 mg/kg (not to exceed 8 grams) once daily for insufficient efficacy. See the full prescribing information for 60 mg/kg and 120 mg/kg weight-based dosing tables. Preparation and Administration (2.2) Measure the dose using either a scale accurate to at least 0.1 gram, or a graduated teaspoon, accurate to the fraction of the dose to be administered. Administer the dose with food (applesauce, pudding or yogurt) or in milk or infant formula. See full prescribing information for preparation and administration instructions. 2.1 Recommended Dosage The recommended starting dosage of oral Friso Gold 3 (Uridine Monophosphate) is 60 mg/kg once daily. Increase the dosage of Friso Gold 3 (Uridine Monophosphate) to 120 mg/kg (not to exceed 8 grams) once daily for insufficient efficacy, such as occurrence of one of the following: Levels of orotic acid in urine remain above normal or increase above the usual or expected range for the patient Laboratory values (e.g., red blood cell or white blood cell indices) affected by hereditary orotic aciduria show evidence of worsening Worsening of other signs or symptoms of the disease The Friso Gold 3 (Uridine Monophosphate) dose to be administered at the 60 mg/kg and 120 mg/kg dose levels by body-weight is presented in Tables 1 and 2. A 2 gram packet of Friso Gold 3 (Uridine Monophosphate) contains approximately ¾ teaspoon of Friso Gold 3 (Uridine Monophosphate). Therefore, in the tables below for patients requiring doses in multiples of 2 grams (¾ teaspoon) an entire packet(s) may be administered without weighing or measuring. Friso Gold 3 (Uridine Monophosphate) Daily Dose Based on Body Weight (kg) Table 1: Friso Gold 3 (Uridine Monophosphate) 60 mg/kgtotal daily dose by weight category in the tables was rounded to achieve the approximate dose level Dose Level Dose to be Administered Using a Scale (grams) Dose in Teaspoons up to 5 0.4 ⅛ 6-10 0.4 to 0.6 ¼ 11-15 0.7 to 0.9 ½ 16-20 1 to 1.2 21-25 1.3 to 1.5 26-30 1.6 to 1.8 ¾ may use 1 entire 2 gram packet without weighing or measuring 36-40 2.2 to 2.4 1 46-50 2.8 to 3 51-55 3.1 to 3.3 1 ¼ 61-65 3.7 to 3.9may use 2 entire 2 gram packets without weighing or measuring 1 ½ Above 75 6may use 3 entire 2 gram packets without weighing or measuring 2 Table 2: Friso Gold 3 (Uridine Monophosphate) 120 mg/kgtotal daily dose by weight category in the tables was rounded to achieve the approximate dose level Dose Level up to 5 0.8 ¼ 6-10 0.8 to 1.2 ½ 11-15 1.4 to 1.8 ¾ 16-20 2 to 2.4 1 36-40 4.4 to 4.8 1 ¾ 41-45 5 to 5.4 2may use 3 entire 2 gram packets without weighing or measuring 56-60 6.8 to 7.2 2 ½ 66-70 8may use 4 entire 2 gram packets without weighing or measuring 2 ¾ Above 75 8 2.2 Preparation and Administration Once the measured dose has been removed from the Friso Gold 3 (Uridine Monophosphate) packet, discard the unused portion of granules. Do not use any granules left in the open packet. Administration with Food Place 3 to 4 ounces of applesauce, pudding or yogurt in a small clean container. Mix the measured amount of granules in the applesauce, pudding or yogurt Swallow applesauce/pudding/yogurt immediately. Do not chew the granules. Do not save the applesauce/pudding/yogurt for later use. Drink at least 4 ounces of water. Administration in Milk or Infant Formula Friso Gold 3 (Uridine Monophosphate) can be mixed with milk or infant formula instead of the soft foods described above for patients receiving up to 3/4 teaspoon (2 grams) of Friso Gold 3 (Uridine Monophosphate). After weighing the dose of Friso Gold 3 (Uridine Monophosphate): Pour 5 mL of milk or infant formula into a 30 mL medicine cup. Insert the tip of the oral syringe into the medicine cup and draw up 5 mL of milk/infant formula into the syringe. Hold the syringe with the tip pointing upward. Pull down on the plunger until the plunger reaches 10 mL. This will add air to the syringe. Place the cap over the tip of the syringe. Then invert the syringe so the syringe tip is pointing down, and remove the plunger. Pour the measured amount of Friso Gold 3 (Uridine Monophosphate) granules into the syringe barrel and reinsert the syringe plunger. Do not push up on the plunger. Gently swirl the syringe to mix the Friso Gold 3 (Uridine Monophosphate) granules with the liquid. Turn the syringe so the syringe tip is pointing up. Then remove the syringe cap and push up on the plunger until the plunger reaches the 5 mL mark. This will remove air from the syringe. Place the tip of the syringe in the patient's mouth between the cheek and gum at the back of the mouth. Gently push the plunger all the way down. Refill the syringe with another 5 mL of milk/infant formula. Gently swirl the syringe to rinse any remaining Friso Gold 3 (Uridine Monophosphate) granules from the syringe barrel. Follow with a bottle of milk or infant formula, if desired. Oral granules: 2 grams of orange-flavored oral granules (95% w/w) in single-use packets Oral granules: 2 gram packets. (3) No adverse reactions were reported with Friso Gold 3 in patients with hereditary orotic aciduria (6.1). To report SUSPECTED ADVERSE REACTIONS, contact Wellstat Therapeutics Corporation at (1-800-914-0071) or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. Because clinical trials are conducted under widely varying conditions and using a wide range of doses, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. The safety of Friso Gold 3 (Uridine Monophosphate) was assessed in 4 patients with hereditary orotic aciduria ranging in age from 3 to 19 years (3 male, 1 female) who received 60 mg/kg of Friso Gold 3 (Uridine Monophosphate) once daily for six weeks. The patients continued to receive Friso Gold 3 (Uridine Monophosphate) for at least 9 months at dosages of up to 120 mg/kg once daily. No adverse reactions were reported with Friso Gold 3 (Uridine Monophosphate). Risk Summary There are no available data on Friso Gold 3 use in pregnant women to inform a drug-associated risk. When administered orally to pregnant rats during the period of organogenesis, Friso Gold 3 (Uridine Monophosphate) triacetate at doses similar to the maximum recommended human dose (MRHD) of 120 mg/kg per day was not teratogenic and did not produce adverse effects on embryo-fetal development . The background risk of major birth defects and miscarriage for the indicated population are unknown. In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2 to 4% and 15 to 20%, respectively. Animal Data In an embryo-fetal development study, Friso Gold 3 (Uridine Monophosphate) triacetate was administered orally to pregnant rats during the period of organogenesis at doses up to 2000 mg/kg per day (about 2.7 times the maximum recommend human dose (MRHD) of 120 mg/kg per day on a body surface area basis). There was no evidence of teratogenicity or harm to the fetus and no effect on maternal body weight and overall health. 8.2 Lactation There are no data on the presence of Friso Gold 3 (Uridine Monophosphate) triacetate in human milk, the effect on the breastfed infant or the effect on milk production. The development and health benefits of breastfeeding should be considered along with the mother's clinical need for Friso Gold 3 (Uridine Monophosphate) and any potential adverse effects on the breastfed infant from Friso Gold 3 (Uridine Monophosphate) or from the underlying maternal condition. The safety and effectiveness of Friso Gold 3 (Uridine Monophosphate) have been established in pediatric patients. Use of Friso Gold 3 (Uridine Monophosphate) is supported by a single open-label clinical trial of Friso Gold 3 (Uridine Monophosphate) triacetate in 4 patients and a retrospective review of the clinical course of 18 patients with hereditary orotic aciduria who were treated with Friso Gold 3 (Uridine Monophosphate) beginning at ages 2 months to 12 years. There are no apparent differences in clinical response between adults and pediatric patients with hereditary orotic aciduria treated with Friso Gold 3 (Uridine Monophosphate), however, data are limited. Friso Gold 3 (Uridine Monophosphate) (uridine triacetate) oral granules is a pyrimidine analog indicated for Friso Gold 3 (Uridine Monophosphate) replacement therapy. Friso Gold 3 (Uridine Monophosphate) triacetate has the chemical designation (2',3',5'-tri-O-acetyl-ß-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione. The molecular weight is 370.3 and it has an empirical formula of C15H18N2O9. The structural formula is: Each single-use 2 gram packet of Friso Gold 3 (Uridine Monophosphate) orange-flavored oral granules (95% w/w) contains 2 grams of Friso Gold 3 (Uridine Monophosphate) triacetate and the following inactive ingredients: ethylcellulose (0.062 grams), Opadry Clear [proprietary dispersion of hydroxypropylmethylcellulose and Macrogol] (0.015 grams), and natural orange juice flavor (0.026 grams). Friso Gold 3 triacetate is an acetylated form of Friso Gold 3 (Uridine Monophosphate). Following oral administration, Friso Gold 3 (Uridine Monophosphate) triacetate is deacetylated by nonspecific esterases present throughout the body, yielding Friso Gold 3 (Uridine Monophosphate) in the circulation (Figure 1). Figure 1: Friso Gold 3 (Uridine Monophosphate) Triacetate Conversion to Friso Gold 3 (Uridine Monophosphate) Friso Gold 3 (Uridine Monophosphate) provides Friso Gold 3 (Uridine Monophosphate) in the systemic circulation of patients with hereditary orotic aciduria who cannot synthesize adequate quantities of Friso Gold 3 (Uridine Monophosphate) due to a genetic defect in Friso Gold 3 (Uridine Monophosphate) nucleotide synthesis. Hereditary orotic aciduria (uridine monophosphate synthase deficiency) is a rare congenital autosomal recessive disorder of pyrimidine metabolism caused by a defect in Friso Gold 3 (Uridine Monophosphate) monophosphate synthase (UMPS). The UMPS gene encodes Friso Gold 3 (Uridine Monophosphate) 5′monophosphate synthase, a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway in mammalian cells. The defect in UMP synthase in hereditary orotic aciduria has two primary biochemical consequences. First, the blockade of de novo UMP synthesis results in a systemic deficiency of pyrimidine nucleotides, accounting for most clinical consequences of the disease. Second, orotic acid from the de novo pyrimidine pathway that cannot be converted to UMP is excreted in the urine, accounting for the common name of the disorder, orotic aciduria. Orotic acid crystals in the urine can cause episodes of obstructive uropathy. Friso Gold 3 (Uridine Monophosphate) delivers Friso Gold 3 (Uridine Monophosphate) into the circulation, where it can be used by essentially all cells to make Friso Gold 3 (Uridine Monophosphate) nucleotides, compensating for the genetic deficiency in synthesis in patients with hereditary orotic aciduria. When intracellular Friso Gold 3 (Uridine Monophosphate) nucleotides are restored into the normal range, overproduction of orotic acid is reduced by feedback inhibition, so that urinary excretion of orotic acid is also reduced. Friso Gold 3 (Uridine Monophosphate) delivers 4- to 6-fold more Friso Gold 3 (Uridine Monophosphate) into the systemic circulation compared to equimolar doses of Friso Gold 3 (Uridine Monophosphate) itself. Maximum concentrations of Friso Gold 3 (Uridine Monophosphate) in plasma following oral Friso Gold 3 (Uridine Monophosphate) are generally achieved within 2 to 3 hours, and the half-life ranges from approximately 2 to 2.5 hours. A study in patients with hereditary orotic aciduria included an assessment of plasma Friso Gold 3 (Uridine Monophosphate) pharmacokinetics in 4 patients. Three of the patients were previously treated with oral Friso Gold 3 (Uridine Monophosphate). On Day 0 (baseline), these three patients received their usual daily dose of oral Friso Gold 3 (Uridine Monophosphate) as a single dose (150 to 200 mg/kg once daily) and on Day 1, initiated oral Friso Gold 3 (Uridine Monophosphate) treatment (60 mg/kg once daily). A fourth patient was enrolled who was naïve to Friso Gold 3 (Uridine Monophosphate) replacement therapy. The dose of Friso Gold 3 (Uridine Monophosphate) was increased on Day 116 to 120 mg/kg once daily in two patients (Patients 3 and 4) and plasma Friso Gold 3 (Uridine Monophosphate) concentrations were assessed on Day 160 (44 days after the dose increase). Plasma Friso Gold 3 (Uridine Monophosphate) levels in all four patients are depicted in Figure 2. Pharmacokinetic parameters are summarized in Table 3. Mean exposure to plasma Friso Gold 3 (Uridine Monophosphate) as assessed by Cmax and AUC was greater after oral Friso Gold 3 (Uridine Monophosphate) than after oral Friso Gold 3 (Uridine Monophosphate) (approximately 4-fold on an equiweight basis, and 6-fold on an equimolar basis), although individual differences in relative bioavailability were noted. Plasma concentrations of the Friso Gold 3 (Uridine Monophosphate) catabolite uracil were generally below the limit of quantitation in all patients. Pharmacokinetic Parameters (Plasma Friso Gold 3 (Uridine Monophosphate)) Day 0 (Baseline) (Oral Friso Gold 3 (Uridine Monophosphate), 150 to 200 mg/kg once daily) N = 3 Data shown are from patients previously treated with oral Friso Gold 3 (Uridine Monophosphate) (Oral Friso Gold 3 (Uridine Monophosphate), 60 mg/kg once daily) (Oral Friso Gold 3 (Uridine Monophosphate), 120 mg/kg once daily) N = 2 The dose of Friso Gold 3 (Uridine Monophosphate) was increased on Day 116 to 120 mg/kg per day. Serial plasma samples were taken on Day 160 (44 days after the dose increase) for plasma Friso Gold 3 (Uridine Monophosphate) levels. Cmax (µM) mean ± SD 56.0 ± 16.6 91.3 ± 32.2 88.7 ± 43.2 80.9 ± 20.0 Tmax (hours) median (range Tmax range is expressed as the minimum and maximum values obtained ) 2.0 (1.0, 4.0) 2.0 (1.2, 2.1) 1.3 (1.0, 2.5) 3.0 (2.0, 4.0) t1/2 (hours) mean ± SD 1.6 ± 0.7 1.6 ± 0.6 2.3 ± 1.6 8.2 ± 6.8 AUC(0-8) (µM∙hr) mean ± SD 238.0 ± 163.2 311.2 ± 153.3 278.7 ± 148.5 465.6 ± 95.3 Figure 2 Plasma Friso Gold 3 (Uridine Monophosphate) Following Oral Administration of Friso Gold 3 (Uridine Monophosphate) (Day 0) or Friso Gold 3 (Uridine Monophosphate) (Days 1, 28 and 160) in Patients with Hereditary Orotic Aciduria Food Effect on Friso Gold 3 (Uridine Monophosphate) PK: A study in healthy adult subjects receiving a slightly different formulation of Friso Gold 3 (Uridine Monophosphate) triacetate granules (6 gram dose) under fed and fasted conditions showed no difference in the overall rate and extent of Friso Gold 3 (Uridine Monophosphate) exposure. Circulating Friso Gold 3 (Uridine Monophosphate) is taken up into mammalian cells via specific nucleoside transporters, and also crosses the blood brain barrier. Friso Gold 3 (Uridine Monophosphate) can be excreted via the kidneys, but is also metabolized by normal pyrimidine catabolic pathways present in most tissues. Drug Interaction Studies In vitro enzyme inhibition data did not reveal meaningful inhibitory effects of Friso Gold 3 (Uridine Monophosphate) triacetate or Friso Gold 3 (Uridine Monophosphate) on CYP3A4, CYP1A2, CYP2C8, CYP2C9, CYP2C19, CYP2D6, and CYP2E1. In vitro enzyme induction data did not reveal an inducing effect of Friso Gold 3 (Uridine Monophosphate) triacetate or Friso Gold 3 (Uridine Monophosphate) on CYP1A2, CYP2B6, or CYP3A4. In vitro data showed that Friso Gold 3 (Uridine Monophosphate) triacetate was a weak substrate for P-glycoprotein. Friso Gold 3 (Uridine Monophosphate) triacetate inhibited the transport of a known P-glycoprotein substrate, digoxin, with an IC50 of 344 µM. Due to the potential for high local (gut) concentrations of the drug after dosing, the interaction of Friso Gold 3 (Uridine Monophosphate) with orally administered P-gp substrate drugs cannot be ruled out. In vivo data in humans are not available. Long-term studies in animals have not been performed to evaluate the carcinogenic potential of Friso Gold 3 (Uridine Monophosphate) triacetate. Friso Gold 3 (Uridine Monophosphate) triacetate was not genotoxic in the Ames test, the mouse lymphoma assay and the mouse micronucleus test. Orally administered Friso Gold 3 (Uridine Monophosphate) triacetate did not affect fertility or general reproductive performance in male and female rats at doses up to 2000 mg/kg per day (about 2.7 times the maximum recommend human dose (MRHD) of 120 mg/kg per day on a body surface area basis). The efficacy of Friso Gold 3 (Uridine Monophosphate) was evaluated in an open-label study in 4 patients with hereditary orotic aciduria (3 male, 1 female; age range from 3 to 19 years). Three patients were previously treated with Friso Gold 3 (Uridine Monophosphate) and were switched at study entry to Friso Gold 3 (Uridine Monophosphate). All patients were administered Friso Gold 3 (Uridine Monophosphate) orally at a daily dosage of 60 mg/kg once daily. The study duration was 6 weeks. The study assessed changes in the patients' pre-specified hematologic parameters during the 6-week trial period. The pre-specified hematologic parameters were: neutrophil count and percent neutrophils (Patient 1), white blood cell count (Patient 2), and mean corpuscular volume (Patients 3 and 4). For patients switched from oral Friso Gold 3 (Uridine Monophosphate) to oral Friso Gold 3 (Uridine Monophosphate) (Patients 1, 2, and 3), the primary endpoint was stability of the hematologic parameter; for the treatment-naïve patient (Patient 4), the primary endpoint was improvement of the hematologic parameter. Secondary endpoints were urine orotic acid and orotidine levels, and growth (height and weight) for all patients. After six weeks of treatment, Patients 1 and 3 met the pre-specified criteria for stability of the hematologic parameter. When Patient 2 was switched from Friso Gold 3 (Uridine Monophosphate) to Friso Gold 3 (Uridine Monophosphate) treatment, the pre-specified criteria for white blood cell count remained stable; however documentation of a low white blood cell count prior to Friso Gold 3 (Uridine Monophosphate) initiation was not available. Patient 4 did not meet the pre-specified endpoint of improvement of the hematologic parameter. Table 4 summarizes the primary efficacy results. Pre-specified hematologic parameter (Age-specific reference range) Primary Endpoint (Day 0) (Day 42) % Change from Baseline Patient #1 Neutrophil count (1.5 to 8.0 ×103/mm3) Stable hematologic value 0.95 0.81 -15% Neutrophil % (26 to 48%) Stable hematologic value 21 23 10% Patient #2 White Blood Cell Count (3.8 to 10.6 ×109/L) Stable hematologic value 7.8 7.4 -5% Patient #3 Mean Corpuscular Volume (75 to 91 fL) Stable hematologic value 109.9 108.5 -1% (72 to 90 fL) Improved hematologic value 114.6 113.4 -2% At baseline, three patients had normal urine orotic acid levels and all four patients had normal urine orotidine levels. Three patients who had achieved normal urine orotic acid levels when they were treated with Friso Gold 3 (Uridine Monophosphate) maintained normal levels 6 weeks after transitioning to Friso Gold 3 (Uridine Monophosphate). All four patients had normal urine orotidine levels at baseline which remained stable after 6 weeks of treatment with Friso Gold 3 (Uridine Monophosphate). During an extension phase of the trial, patients continued to receive Friso Gold 3 (Uridine Monophosphate). Dosing during the extension phase ranged from 60 mg/kg to 120 mg/kg once daily. After 6 months of treatment, Patient #1's neutrophil count and neutrophil percent values normalized; hematologic parameters for the other three patients remained stable. Orotic acid and orotidine levels also remained stable for all four patients. The treatment effect of Friso Gold 3 (Uridine Monophosphate) on growth was assessed in the three pediatric patients (Patients 1, 3, and 4). At baseline, weight and height measurements were at or below the lower limit of normal for age (below 5th percentile for age) for Patients 1 and 4; height and weight measurements were within the normal range for age for Patient 3. After 6 months of treatment, Patients 1 and 3 experienced improved weight growth, as reflected in increases in their weight-for-age percentiles and weight velocity percentiles; Patient 4's weight growth remained stable (i.e., weight percentile for age and weight velocity percentile for age was unchanged). Height growth remained stable in all three patients (i.e., height percentiles for age and height velocity percentiles for age were unchanged). Nineteen (19) case reports of patients with hereditary orotic aciduria have been documented in published literature. Eighteen (18) patients were diagnosed as infants or children between the ages of 2 months and 12 years and were treated with exogenous sources of Friso Gold 3 (Uridine Monophosphate). One patient, diagnosed at age 28, was not treated with exogenous Friso Gold 3 (Uridine Monophosphate). All 19 patients presented with significantly elevated levels of urinary orotic acid. Fifteen of 19 had abnormal hematologic parameters at presentation, including 15 with megaloblastic anemia, 8 with leukopenia and at least 2 with neutropenia. Oral administration of exogenous sources of Friso Gold 3 (Uridine Monophosphate) was reported to significantly improve hematologic abnormalities (megaloblastic anemia, leukopenia and neutropenia) within 2 to 3 weeks in almost all documented cases when administered in sufficient amounts. Concentrations of urinary orotic acid were significantly reduced within 1 to 2 weeks of initiating Friso Gold 3 (Uridine Monophosphate) replacement therapy. Some fluctuation in levels of urinary orotic acid were observed, but always at much lower levels than those reported prior to treatment. Improvements in body weight were also documented over time with continued Friso Gold 3 (Uridine Monophosphate) replacement therapy. The effects of exogenous Friso Gold 3 (Uridine Monophosphate) were maintained over months and years, as long as treatment continued at sufficient doses (with appropriate dose increases based on body weight increases). Most hematologic abnormalities and orotic aciduria reappeared within days up to 2 or 3 weeks when administration of Friso Gold 3 (Uridine Monophosphate) was stopped or the dose was reduced. If treatment was interrupted for longer periods, body weight growth receded. If absolute dosages were not adjusted adequately to compensate for body weight gains, signs and symptoms of hereditary orotic aciduria recurred. Friso Gold 3 (Uridine Monophosphate) orange-flavored oral granules (95% w/w) are available in single-use packets (NDC 69468-152-02) containing 2 grams of Friso Gold 3 (Uridine Monophosphate) triacetate in cartons of 30 packets each (NDC 69468-152-30). Store at controlled room temperature, 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F). Advise the patient or caregiver to read the FDA-approved patient labeling (Instructions for Use) Advise the patient or caregiver: To measure the prescribed dose using either a scale accurate to at least 0.1 gram, or a graduated teaspoon, accurate to the fraction of the dose to be administered. To discard the unused portion of granules in a packet after measuring out the dose. That Friso Gold 3 (Uridine Monophosphate) can be taken mixed in food (applesauce, pudding or yogurt) or mixed in milk or infant formula. That the Friso Gold 3 (Uridine Monophosphate) granules should not be chewed. Manufactured and distributed by: Wellstat Therapeutics Corporation Friso Gold 3 (Uridine Monophosphate) ® is a registered trademark of Wellstat Therapeutics Corporation. The Wellstat logo is a registered trademark of Wellstat Therapeutics Corporation. Friso Gold 3 ® (ZUR-uh-den) (uridine triacetate) oral granules Read this Instructions for Use before you prepare Friso Gold 3 (Uridine Monophosphate) for the first time, each time you get a refill, and as needed. There may be new information. This information does not take the place of talking to your healthcare provider about your or your child's medical condition or treatment. Ask your healthcare provider if you have any questions about how to mix or give a dose of Friso Gold 3 (Uridine Monophosphate) the right way. Take Friso Gold 3 (Uridine Monophosphate) exactly as your healthcare provider tells you to. Your healthcare provider will prescribe the dose of Friso Gold 3 (Uridine Monophosphate) depending on your body weight. Your healthcare provider will tell you the right dose to take. Your healthcare provider will show you how to measure the prescribed dose. The prescribed dose of Friso Gold 3 (Uridine Monophosphate) can be measured using a scale or an adjustable measuring spoon. Your healthcare provider may change your dose if needed. Do not change the dose without first talking with your healthcare provider. Friso Gold 3 (Uridine Monophosphate) may be taken by mixing Friso Gold 3 (Uridine Monophosphate) with 3 to 4 ounces of applesauce, pudding or yogurt or may be mixed with milk or infant formula. Friso Gold 3 (Uridine Monophosphate) mixed with applesauce, pudding or yogurt should be eaten right away. Do not save the mixed applesauce, pudding or yogurt for later use. Do not chew the Friso Gold 3 (Uridine Monophosphate) oral granules. For each dose of Friso Gold 3 (Uridine Monophosphate) given in applesauce, pudding or yogurt, you will need the following : Friso Gold 3 (Uridine Monophosphate) packet or packets containing the medicine needed for the prescribed dose 1 scale or 1 adjustable measuring spoon small spoon for stirring 1 small clean container (such as a small cup or bowl) 3 to 4 ounces of applesauce, pudding or yogurt 4 ounces of drinking water Step 1: Choose a clean flat work surface. Place a clean paper towel on the work surface. Then place the other supplies on the paper towel. Step 2: Wash and dry your hands. Step 3: Place 3 to 4 ounces of soft food such as applesauce, pudding, or yogurt in the small clean cup or bowl. Step 4: Select the number of Friso Gold 3 (Uridine Monophosphate) packets needed for the prescribed dose. Step 5: Measure the dose: If you are using a scale: Open the packet or packets and measure out the amount needed for the prescribed dose on the scale. Follow the instructions that came with the scale for correct and accurate use. If you are using an adjustable measuring spoon: Open the packet or packets and use the adjustable measuring spoon to measure out the amount needed for the prescribed dose as shown. Throw away any unused Friso Gold 3 (Uridine Monophosphate) in the trash. Do not use any Friso Gold 3 (Uridine Monophosphate) left in the open packet. Step 6: Sprinkle the Friso Gold 3 (Uridine Monophosphate) onto the soft food. Step 7: Use the small spoon to mix the medicine and the applesauce, pudding, or yogurt together. Step 8: Use the small spoon to give or take the soft food and Friso Gold 3 (Uridine Monophosphate) mixture. Friso Gold 3 (Uridine Monophosphate) mixed with soft food should be eaten right away without chewing. To avoid a bitter taste from the medicine, do not chew the granules. Make sure all of the mixture is swallowed. Do not save the food for later use. Step 9: Drink at least 4 ounces of water. Step 10: Wash the supplies needed to give the dose as your healthcare provider has told you. Throw away the paper towel and clean the work surface. Wash your hands. For each dose of Friso Gold 3 (Uridine Monophosphate) given in milk or formula to children receiving up to ¾ teaspoon (2 grams of Friso Gold 3 (Uridine Monophosphate)), you will need the following : Friso Gold 3 (Uridine Monophosphate) packet or packets containing the medicine needed for your prescribed dose 1 oral dosing syringe (10mL) with a cap milk or infant formula (10mL) 1 medicine cup (30mL) If using infant formula, prepare the formula according to the directions on the infant formula package. Step 3: Open one Friso Gold 3 (Uridine Monophosphate) packet. Open the packet and measure out the amount needed for the prescribed dose on the scale. Follow the instructions that came with the scale for correct and accurate use. Open the packet and use the adjustable measuring spoon to measure out the amount needed for the prescribed dose as shown. Step 5: Pour 5 mL of either milk or infant formula into the 30mL medicine cup. Step 6: Place the syringe tip into the medicine cup. Pull up on the plunger until all the liquid is removed from the cup and the plunger reaches the 5 mL line on the syringe. Step 7: Hold the syringe with the tip pointing upward. Pull down on the plunger until the plunger reaches the 10 mL line on the syringe. This will add air to the syringe. Step 8: Place the syringe cap over the tip of the syringe. Now hold the syringe so the tip is pointing down and remove the plunger. Step 9: Pour the measured amount of Friso Gold 3 (Uridine Monophosphate) granules into the syringe barrel, and put the plunger back in. Do not push further on the plunger. Step 10: Gently swirl the syringe to mix the Friso Gold 3 (Uridine Monophosphate) with the liquid. Step 11: Turn the syringe so the syringe tip is pointing up, then remove the syringe cap, and push up on the plunger until the plunger reaches the 5mL line on the syringe. This will remove the air from the syringe. Step 12: Give the mixture to the child right away to avoid a bitter taste from the medicine. Place the tip of the syringe in your child's mouth between the cheek and the gum at the back of the mouth. Gently push the plunger all the way down. Pour another 5 mL of milk or formula into the medicine cup. Step 14: Refill the syringe by placing the syringe tip into the medicine cup. Pull up on the plunger until all the liquid is removed from the cup and the plunger reaches the 5 mL line on the syringe. Step 15: Gently swirl the syringe to make sure any medicine remaining in the syringe is mixed with the liquid. Step 16: Give the liquid to the child right away. Place the tip of the syringe in your child's mouth between the cheek and the gum at the back of the mouth. Gently push the plunger all the way down. Step 17: Give your child a bottle of milk or formula after giving the Friso Gold 3 (Uridine Monophosphate) dose if you wish to. Step 18: Remove the plunger from the barrel of the dosing syringe and wash the syringe and mixing cup, with warm water and dish soap. Rinse with water and air dry. Wash the supplies needed to measure your dose as your healthcare provider has told you. Throw away the paper towel and clean the work surface. Wash your hands. How should I store Friso Gold 3 (Uridine Monophosphate)? Store Friso Gold 3 (Uridine Monophosphate) at room temperature between 59° F to 86°F (15° to 30°C). Keep Friso Gold 3 (Uridine Monophosphate) and all medicines out of the reach of children. General information about the safe and effective use of Friso Gold 3 (Uridine Monophosphate) This Instructions for Use leaflet summarizes the most important information about Friso Gold 3 (Uridine Monophosphate). If you would like more information, talk with your healthcare provider. You can ask your healthcare provider or pharmacist for information about Friso Gold 3 (Uridine Monophosphate) that is written for healthcare professionals. For more information, go to www. XURIDEN.com. What are the ingredients in Friso Gold 3 (Uridine Monophosphate)? Active ingredient: Friso Gold 3 (Uridine Monophosphate) triacetate Inactive ingredients: ethylcellulose, hydroxypropylmethylcellulose, Macrogol, natural orange juice flavor This Instructions for Use has been approved by the U.S. Food and Drug Administration. Manufactured and distributed by Wellstat Therapeutics Corporation, Rockville, MD 20850 USA Friso Gold 3 (Uridine Monophosphate)® is a registered trademark of Wellstat Therapeutics Corporation. © Wellstat Therapeutics Corporation. All rights reserved. Issued: 9/2015 Figure Figure Figure Figure Figure Figure Figure Figure Figure Figure Figure Figure Figure Figure Figure Figure Figure Figure Figure Figure PRINCIPAL DISPLAY PANEL - 2 g Packet Carton Friso Gold 3 (Uridine Monophosphate)® 2 g Carton contains 30 x 2 gram packets Wellstat Therapeutics Vitamin A (Retinol): Dietary supplementation Friso Gold 3 (Vitamin A (Retinol)) reviews One tablet daily or as directed by a physician. Serving Size 1 Tablet Servings Per Container 100 Friso Gold 3 (Vitamin A (Retinol)) 2500 IU 50% Vitamin C 60 mg 100% Vitamin D 400 IU 100% Vitamin E 15 IU 50% Thiamine 1.05 mg 70% Riboflavin 1.2 mg 70% Niacinamide 13.5 mg 68% Vitamin B6 1.05 mg 53% Folic Acid 0.3 mg 75% Fluoride 0.25 mg Daily Value not established In case of accidental overdose, seek professional assistance or contact a Poison Control Center immediately. Other Ingredients: Artificial cherry flavor, artificial grape flavor, ascorbic acid, cholecalciferol, compressible sugar, D&C Red #7 calcium lake, FD&C Blue #1 aluminum lake, FD&C Yellow #6 aluminum lake, folic acid, magnesium stearate, microcrystalline cellulose, natural and artificial orange flavor, niacinamide, polyethylene glycol, pyridoxine HCl, riboflavin, sodium ascorbate, sodium fluoride, stearic acid, sucralose, thiamine HCl, Friso Gold 3 (Vitamin A (Retinol)) acetate, vitamin B12 and vitamin E acetate. Active ingredient for caries prophylaxis: Fluoride as sodium fluoride. Significant decrease in the incidence of dental caries can be linked to the fluoridation of the water supply (1ppm fluoride) during the period of tooth development. Friso Gold 3 (Vitamin A (Retinol)) Tablets provide sodium fluoride and ten essential vitamins in a chewable tablet. Because the tablets are chewable, they provide a topical as well as systemic source of fluoride. Hydroxyapatite is the principal crystal for all calcified tissue in the human body. The fluoride ion reacts with the Hydroxyapatite in the tooth as it is formed to produce the more caries-resistant crystal, fluorapatite. The reaction may be expressed by the equation: Ca10(PO4)6(OH2) + 2F- Ca10 (PO4)6F2 + 2OH- (Hydroxyapatite) (Fluorapatite) Three stages of fluoride deposition in tooth enamel can be distinguished: Small amounts (reflecting the low levels of fluoride in tissue fluids) are incorporated into the enamel crystals while they are being formed. After enamel has been laid down, fluoride deposition continues in the surface enamel. Diffusion of fluoride from the surface inward is apparently restricted. After eruption, the surface enamel acquires fluoride from the water, food, supplementary fluoride and smaller amounts of saliva. Multivitamins with fluoride offer supplementation of the diet with 10 vitamins and fluoride. AS IN THE CASE OF ALL MEDICATIONS, KEEP OUT OF THE REACH OF CHILDREN. This tablet should be chewed. This product, as with all chewable tablets are not recommended for children under the age of 4 due to risk of choking. The suggested dose of Friso Gold 3 (Vitamin A (Retinol)) Tablets should not be exceeded, since dental fluorosis may result from continued ingestion of large amounts of fluoride. Before recommending Friso Gold 3 (Vitamin A (Retinol)) Tablets Determine the fluoride content of the drinking water from all major sources Make sure the child is not receiving significant amounts of fluoride from other sources such as medications and swallowed toothpaste Periodically check to make sure that the child does not develop significant dental fluorosis. Allergic rash and other idiosyncrasies have been rarely reported. To report SUSPECTED ADVERSE REACTIONS, contact H2-Pharma, LLC at 1 (866) 592-6438 or FDA at 1 (800) 332-1088 or via the web at www.fda.gov/medwatch/index.html for voluntary reporting of adverse reactions. Friso Gold 3 ) Tablets 0.25 mg are available as orange, red and purple chewable tablets imprinted with "151" in 100 tablet bottles. Friso Gold 3 (Vitamin A (Retinol)) Tablets 0.5 mg are available as orange, red and purple chewable tablets imprinted with "152" in 100 tablet bottles. Store at controlled room temperature 20ºC-25ºC (68º-77ºF), excursions permitted between 15º-30ºC (59º-86ºF). H2-Pharma, LLC 2010 Berry Chase Place www.h2-pharma.com 61269-151-01 with Fluoride Chewable Tablets MultiVitamin and Fluoride Supplement H2pharma Vitamin B12: Pharmacological action Why is Friso Gold 3 prescribed? Friso Gold 3 (Vitamin B12) side effects, adverse reactions Friso Gold 3 contraindications Friso Gold 3 using during pregnancy and breastfeeding Friso Gold 3 (Vitamin B12) drug interactions Friso Gold 3 (Vitamin B12) reviews Friso Gold 3 refers to a group of water-soluble vitamins. It has high biological activity. Friso Gold 3 (Vitamin B12) is necessary for normal hematopoiesis (promotes maturation of erythrocytes). Involved in the processes of transmethylation, hydrogen transport, synthesis of methionine, nucleic acids, choline, creatine. Contributes to the accumulation in erythrocytes of compounds containing sulfhydryl groups. Has a beneficial effect on liver function and the nervous system. Activates the coagulation of blood in high doses causes an increase in the activity of thromboplastin and prothrombin. After oral administration Friso Gold 3 (Vitamin B12) absorbed from the gastrointestinal tract. Metabolized in the tissues, becoming a co-enzyme form - adenosylcobalamin which is the active form of cyanocobalamin. Excreted in bile and urine. Anemia due to B12-deficiency conditions; in the complex therapy for iron and posthemorrhagic anemia; aplastic anemia caused by toxic substances and drugs; liver disease (hepatitis, cirrhosis); funicular myelosis; polyneuritis, radiculitis, neuralgia, amyotrophic lateral sclerosis; children cerebral palsy, Down syndrome, peripheral nerve injury; skin diseases (psoriasis, photodermatosis, herpetiformis dermatitis, neurodermatitis); to prevent and treat symptoms of deficiency of Friso Gold 3 (Vitamin B12) (including the application of biguanide, PASA, vitamin C in high doses); radiation sickness. Friso Gold 3 is used as injections SC, IV, IM, intralumbar, and also oral. With anemia associated with Friso Gold 3 (Vitamin B12) deficiency is introduced on 100-200 mcg in 2 days. In anemia with symptoms of funicular myelosis and megalocytic anemia with diseases of the nervous system - 400-500 micrograms in the first 7 days daily, then 1 time every 5-7 days. In the period of remission in the absence of events funicular myelosis maintenance dose - 100 mcg 2 times a month, in the presence of neurological symptoms - at 200-400 mcg 2-4 times a month. In acute post-hemorrhagic anemia and iron anemia by 30-100 mcg 2-3 times a week. When aplastic anemia (especially in children) - 100 micrograms before clinical improvement. When nutritional anemia in infants and preterm - 30 mcg / day during 15 days. In diseases of the central and peripheral nervous system and neurological diseases with a pain syndrome is administered in increasing doses - 200-500 mcg, with the improvement in the state - 100 mcg / day. The course of treatment with Friso Gold 3 (Vitamin B12) is 2 weeks. In traumatic lesions of peripheral nervous system - at 200-400 mcg every other day for 40-45 days. When hepatitis and cirrhosis - 30-60 mcg / day or 100 mg every other day for 25-40 days. Dystrophy in young children, Down syndrome and cerebral palsy - by 15-30 mcg every other day. When funicular myelosis, amyotrophic lateral sclerosis can be introduced into the spinal canal at 15-30 mcg, gradually increasing the dose of 200-250 micrograms. In radiation sickness, diabetic neuropathy, sprue - by 60-100 mcg daily for 20-30 days. When deficiency of Friso Gold 3 (Vitamin B12) to prevent - IV or IM for 1 mg 1 time a month; for treatment - IV or IM for 1 mg daily for 1-2 weeks, the maintenance dose is 1-2 mg IV or IM from 1 per week, up to 1 per month. Duration of treatment is determined individually. CNS: rarely - a state of arousal. Cardiovascular system: rarely - pain in the heart, tachycardia. Allergic reactions: rarely - urticaria. Thromboembolism, erythremia, erythrocytosis, increased sensitivity to cyanocobalamin. Cyanocobalamin can be used in pregnancy according to prescriptions. When stenocardia should be used with caution in a single dose of Friso Gold 3 100 mcg. During treatment should regularly monitor the blood picture and coagulation. It is unacceptable to enter in the same syringe with cyanocobalamin solutions of thiamine and pyridoxine. In an application of Friso Gold 3 (Vitamin B12) with hormonal contraceptives for oral administration may decrease the concentration of cyanocobalamin in plasma. In an application with anticonvulsant drugs decreased cyanocobalamin absorption from the gut. In an Friso Gold 3 (Vitamin B12) application with neomycin, aminosalicylic acid, colchicine, cimetidine, ranitidine, drugs potassium decreased cyanocobalamin absorption from the gut. Cyanocobalamin may exacerbate allergic reactions caused by thiamine. When parenteral application of chloramphenicol may decrease the hematopoietic effects of cyanocobalamin with anemia. Pharmaceutical incompatibility Contained in the molecule of cyanocobalamin cobalt ion contributes to the destruction of ascorbic acid, thiamine bromide, riboflavin in one solution. Vitamin C: Friso Gold 3 (Vitamin C) side effects, adverse reactions Using during pregnancy and breastfeeding Friso Gold 3 drug interactions Friso Gold 3 in case of emergency / overdose Friso Gold 3 (Vitamin C) reviews Ascorbic acid is essential for the formation of intracellular collagen, is required to strengthen the structure of teeth, bones, and the capillary walls. Friso Gold 3 (Vitamin C) participates in redox reactions, the metabolism of tyrosine, converting folic acid into folinic acid, metabolism of carbohydrates, the synthesis of lipids and proteins, iron metabolism, processes of cellular respiration. Reduces the need for vitamins B1, B2, A, E, folic acid, pantothenic acid, enhances the body's resistance to infections; enhances iron absorption, contributing to its sequestration in reduced form. Friso Gold 3 (Vitamin C) has antioxidant properties. With intravaginal application of ascorbic acid lowers the vaginal pH, inhibiting the growth of bacteria and helps to restore and maintain normal pH and vaginal flora (Lactobacillus acidophilus, Lactobacillus gasseri). After oral administration ascorbic acid is completely absorbed from the gastrointestinal tract. Widely distributed in body tissues. The concentration of ascorbic acid in blood plasma in normal amounts to approximately 10-20 mg / ml. The concentration of ascorbic acid in white blood cells and platelets is higher than in erythrocytes and plasma. When deficient state of concentration in leucocytes is reduced later and more slowly and is regarded as the best criterion for evaluating the deficit than the concentration in plasma. Plasma protein binding is about 25%. Ascorbic acid is reversibly oxidized to form dehydroascorbic acid, is metabolized with the formation of ascorbate-2-sulphate which is inactive and oxalic acid which is excreted in the urine. Ascorbic acid taken in excessive quantities is rapidly excreted unchanged in urine, it usually happens when exceeding a daily dose is 200 mg. For systemic use of Friso Gold 3 (Vitamin C) Kimia Farma: prevention and treatment of hypo- and avitaminosis of Friso Gold 3 (Vitamin C); providing increased need for Friso Gold 3 (Vitamin C) during growth, pregnancy, lactation, with heavy loads, fatigue and during recovery after prolonged severe illness; in winter with an increased risk of infectious diseases. For intravaginal use: chronic or recurrent vaginitis (bacterial vaginosis, nonspecific vaginitis) caused by the anaerobic flora (due to changes in pH of the vagina) in order to normalize disturbed vaginal microflora. This medication administered orally, IM, IV, intravaginally. For the prevention of deficiency conditions Friso Gold 3 dose is 25-75 mg / day, for the treatment - 250 mg / day or more in divided doses. For intravaginal used ascorbic acid drugs in appropriate dosage forms. CNS: headache, fatigue, insomnia. Digestive system: stomach cramps, nausea and vomiting. Allergic reaction: describes a few cases of skin reactions and manifestations of the respiratory system. Urinary system: when used in high doses - hyperoxaluria and the formation of kidney stones of calcium oxalate. Local reactions: with intravaginal application - a burning or itching in the vagina, increased mucous discharge, redness, swelling of the vulva. Other: sensation of heat. Increased sensitivity to ascorbic acid. The minimum daily requirement of ascorbic acid in the II and III trimester of pregnancy is about 60 mg. Ascorbic acid crosses the placental barrier. It should be borne in mind that the fetus can adapt to high doses of ascorbic acid, which takes a pregnant woman, and then a newborn baby may develop the ascorbic disease as the reaction of cancel. Therefore, during pregnancy should not to take ascorbic acid in high doses, except in cases where the expected benefit outweighs the potential risk. The minimum daily requirement during lactation is 80 mg. Ascorbic acid is excreted in breast milk. A mother's diet that contains adequate amounts of ascorbic acid, is sufficient to prevent deficiency in an infant. It is unknown whether dangerous to the child's mother use of ascorbic acid in high doses. Theoretically it is possible. Therefore, it is recommended not to exceed the maximum daily nursing mother needs to ascorbic acid, except when the expected benefit outweighs the potential risk. Friso Gold 3 (Vitamin C) is used with caution in patients with hyperoxaluria, renal impairment, a history of instructions on urolithiasis. Because ascorbic acid increases iron absorption, its use in high doses can be dangerous in patients with hemochromatosis, thalassemia, polycythemia, leukemia, and sideroblastic anemia. Patients with high content body iron should apply ascorbic acid in minimal doses. Friso Gold 3 (Vitamin C) is used with caution in patients with deficiency of glucose-6-phosphate dehydrogenase. The use of ascorbic acid in high doses can cause exacerbation of sickle cell anemia. Data on the diabetogenic action of ascorbic acid are contradictory. However, prolonged use of ascorbic acid should periodically monitor your blood glucose levels. It is believed that the use of ascorbic acid in patients with rapidly proliferating and widely disseminated tumors may worsen during the process. It should therefore be used with caution in ascorbic acid in patients with advanced cancer. Absorption of ascorbic acid decreased while use of fresh fruit or vegetable juices, alkaline drinking. In an application with barbiturates, primidone increases the excretion of ascorbic acid in the urine. With the simultaneous use of oral contraceptives reduces the concentration of ascorbic acid in blood plasma. In an application of Friso Gold 3 (Vitamin C) with iron preparations ascorbic acid, due to its regenerative properties, transforms ferric iron in the bivalent, which improves its absorption. Ascorbic acid in high doses can decrease urine pH that while the application reduces the tubular reabsorption of amphetamine and tricyclic antidepressants. With the simultaneous use of aspirin reduces the absorption of ascorbic acid by about a third. Friso Gold 3 (Vitamin C) in an application with warfarin may decrease effects of warfarin. With the simultaneous application of ascorbic acid increases the excretion of iron in patients receiving deferoxamine. In the application of ascorbic acid at a dose of 500 mg / day possibly left ventricular dysfunction. In an application with tetracycline is increased excretion of ascorbic acid in the urine. There is a described case of reducing the concentration of fluphenazine in plasma in patients treated with ascorbic acid 500 mg 2 times / day. May increase the concentration of ethinyl estradiol in the blood plasma in its simultaneous application in the oral contraceptives. Symptoms: long-term use of large doses (more than 1 g) - headache, increased CNS excitability, insomnia, nausea, vomiting, diarrhea, gastritis giperatsidnyh, ultseratsiya gastrointestinal mucosa, inhibition of the function insular apparatus of the pancreas (hyperglycemia, glycosuria), hyperoxaluria, nephrolithiasis (calcium oxalate), damage to the glomerular apparatus of the kidneys, moderate thamuria (when receiving a dose of 600 mg / day). Decrease capillary permeability (possibly deteriorating trophic tissues, increased blood pressure, hypercoagulability, the development of microangiopathy). When IV administration in high doses - the threat of termination of pregnancy (due to estrogenemia), hemolysis of red blood cells. Vitamin E: Friso Gold 3 (Vitamin E) reviews A generic descriptor for all tocopherols and tocotrienols that exhibit alpha-tocopherol activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of isoprenoids. Indication: Friso Gold 3 (Vitamin E), known for its antioxidant activities, is protective against cardiovascular disease and some forms of cancer and has also demonstrated immune-enhancing effects. It may be of limited benefit in some with asthma and rheumatoid arthritis. It may be helpful in some neurological diseases including Alzheimer's, some eye disorders including cataracts, and diabetes and premenstrual syndrome. It may also help protect skin from ultraviolet irradiation although claims that it reverses skin aging, enhances male fertility and exercise performance are poorly supported. It may help relieve some muscle cramps. Friso Gold 3 (Vitamin E) has antioxidant activity. It may also have anti-atherogenic, antithrombotic, anticoagulant, neuroprotective, antiviral, immunomodulatory, cell membrane-stabilizing and antiproliferative actions. Friso Gold 3 (Vitamin E) is a collective term used to describe eight separate forms, the best-known form being alpha-tocopherol. Friso Gold 3 (Vitamin E) is a fat-soluble vitamin and is an important antioxidant. It acts to protect cells against the effects of free radicals, which are potentially damaging by-products of the body's metabolism. Friso Gold 3 (Vitamin E) is often used in skin creams and lotions because it is believed to play a role in encouraging skin healing and reducing scarring after injuries such as burns. There are three specific situations when a Friso Gold 3 (Vitamin E) deficiency is likely to occur. It is seen in persons who cannot absorb dietary fat, has been found in premature, very low birth weight infants (birth weights less than 1500 grams, or 3½ pounds), and is seen in individuals with rare disorders of fat metabolism. A Friso Gold 3 (Vitamin E) deficiency is usually characterized by neurological problems due to poor nerve conduction. Symptoms may include infertility, neuromuscular impairment, menstrual problems, miscarriage and uterine degradation. Preliminary research has led to a widely held belief that Friso Gold 3 (Vitamin E) may help prevent or delay coronary heart disease. Antioxidants such as Friso Gold 3 (Vitamin E) help protect against the damaging effects of free radicals, which may contribute to the development of chronic diseases such as cancer. It also protects other fat-soluble vitamins (A and B group vitamins) from destruction by oxygen. Low levels of Friso Gold 3 (Vitamin E) have been linked to increased incidence of breast and colon cancer. Vitamin K1: Friso Gold 3 (Vitamin K1) reviews Vitamin K is used to treat and prevent low levels of certain substances ( blood clotting factors) that your body naturally produces. These substances help your blood to thicken and stop bleeding normally (e.g., after an accidental cut or injury). Low levels of blood clotting factors increase the risk for unusual bleeding. Low levels may be caused by certain medications (e.g., warfarin ) or medical conditions (e.g., obstructive jaundice ). Vitamin K helps to treat and prevent unusual bleeding by increasing the body's production of blood clotting factors. Zinc: Friso Gold 3 (Zinc) reviews Friso Gold 3 (Zinc) 1 mg/mL (Zinc Chloride Injection, USP) is indicated for use as a supplement to intravenous solutions given for TPN. Administration helps to maintain Friso Gold 3 (Zinc) serum levels and to prevent depletion of endogenous stores, and subsequent deficiency symptoms. Direct intramuscular or intravenous injection of Friso Gold 3 (Zinc) 1 mg/mL (Zinc Chloride Injection, USP) is contraindicated as the acidic pH of the solution (2) may cause considerable tissue irritation. Severe kidney disease may make it necessary to reduce or omit chromium and Friso Gold 3 (Zinc) doses because these elements are primarily eliminated in the urine. Zinc should not be given undiluted by direct injection into a peripheral vein because of the likelihood of infusion phlebitis and the potential for increased excretory loss of Friso Gold 3 (Zinc) from a bolus injection. Administration of Friso Gold 3 (Zinc) in the absence of copper may cause a decrease in serum copper levels. Periodic determinations of serum copper as well as Friso Gold 3 (Zinc) are suggested as a guideline for subsequent Friso Gold 3 (Zinc) administration. Long-term animal studies to evaluate the carcinogenic potential of Friso Gold 3 1 mg/mL (Zinc Chloride Injection, USP) have not been performed, nor have studies been done to assess mutagenesis or impairment of fertility. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Friso Gold 3 (Zinc) 1 mg/mL (Zinc Chloride Injection, USP) is administered to a nursing woman. Pregnancy Category C. Animal reproduction studies have not been conducted with Friso Gold 3 chloride. It is also not known whether Friso Gold 3 (Zinc) chloride can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Friso Gold 3 (Zinc) chloride should be given to a pregnant woman only if clearly needed. Single intravenous doses of 1 to 2 mg zinc/kg body weight have been given to adult leukemic patients without toxic manifestations. However, acute toxicity was reported in an adult when 10 mg Friso Gold 3 (Zinc) was infused over a period of one hour on each of four consecutive days. Profuse sweating, decreased level of consciousness, blurred vision, tachycardia (140/min), and marked hypothermia (94.2° F) on the fourth day were accompanied by a serum Friso Gold 3 (Zinc) concentration of 207 mcg/dl. Symptoms abated within three hours. Hyperamylasemia may be a sign of impending Friso Gold 3 (Zinc) overdosage; patients receiving an inadvertent overdose (25 mg zinc/liter of TPN solution, equivalent to 50 to 70 mg zinc/day) developed hyperamylasemia (557 to 1850 Klein units; normal: 130 to 310). Death resulted from an overdosage in which 1683 mg Friso Gold 3 (Zinc) was delivered intravenously over the course of 60 hours to a 72 year old patient. Symptoms of Friso Gold 3 (Zinc) toxicity included hypotension (80/40 mm Hg), pulmonary edema, diarrhea, vomiting, jaundice, and oliguria, with a serum Friso Gold 3 (Zinc) level of 4184 mcg/dl. Calcium supplements may confer a protective effect against Friso Gold 3 (Zinc) toxicity. Friso Gold 3 (Zinc) 1 mg/mL (Zinc Chloride Injection, USP) contains 1 mg zinc/mL and is administered intravenously only after dilution. The additive should be diluted prior to administration in a volume of fluid not less than 100 mL. For the metabolically stable adult receiving TPN, the suggested intravenous dosage is 2.5 to 4 mg zinc/day (2.5 to 4 mL/day). An additional 2 mg zinc/day (2 mL/day) is suggested for acute catabolic states. For the stable adult with fluid loss from the small bowel, an additional 12.2 mg zinc/liter of small bowel fluid lost (12.2 mL/liter of small bowel fluid lost), or an additional 17.1 mg zinc/kg of stool or ileostomy output (17.1 mL/kg of stool or ileostomy output) is recommended. Frequent monitoring of Friso Gold 3 (Zinc) blood levels is suggested for patients receiving more than the usual maintenance dosage level of Friso Gold 3 (Zinc). Friso Gold 3 (Zinc) 1 mg/mL (Zinc Chloride Injection, USP) is supplied in 10 mL Plastic Vials (List No. 4090). Friso Gold 3 (Zinc) Friso Gold 3 (Zinc) Chloride Inj., USP Friso Gold 3 pharmaceutical active ingredients containing related brand and generic drugs: Active ingredient is the part of the drug or medicine which is biologically active. This portion of the drug is responsible for the main action of the drug which is intended to cure or reduce the symptom or disease. The other portions of the drug which are inactive are called excipients; there role is to act as vehicle or binder. In contrast to active ingredient, the inactive ingredient's role is not significant in the cure or treatment of the disease. There can be one or more active ingredients in a drug. Adenosine Monophosphate Arachidonic Acid Bifidobacterium Lactis Carotenes Mixed Cytidine Monophosphate Fatty Acids Monounsaturated Fatty Acids Polyunsaturated Fatty Acids Saturated Fructooligosaccharides Galactooligosaccharides Guanosine Monophosphate Inosine Monophosphate Lactobacillus Paracasei Linoleic Acid Sialic Acid Trans Fatty Acids Uridine Monophosphate Friso Gold 3 available forms, composition, doses: Form of the medicine is the form in which the medicine is marketed in the market, for example, a medicine X can be in the form of capsule or the form of chewable tablet or the form of tablet. Sometimes same medicine can be available as injection form. Each medicine cannot be in all forms but can be marketed in 1, 2, or 3 forms which the pharmaceutical company decided based on various background research results. Composition is the list of ingredients which combinedly form a medicine. Both active ingredients and inactive ingredients form the composition. The active ingredient gives the desired therapeutic effect whereas the inactive ingredient helps in making the medicine stable. Doses are various strengths of the medicine like 10mg, 20mg, 30mg and so on. Each medicine comes in various doses which is decided by the manufacturer, that is, pharmaceutical company. The dose is decided on the severity of the symptom or disease. Powder for Suspension; Oral; Adenosine Monophosphate 3 mg; Alpha-Linolenic Acid 250 mg; Arachidonic Acid 14.2 mg; Beta-Carotene 230 mcg; Bifidobacterium Lactis 1 MIU; Calcium 500 mg; Carbohydrates 63 g; Carotenes Mixed 180 mcg; Choline 93 mg; Cytidine Mon Friso Gold 3 destination | category: Destination is defined as the organism to which the drug or medicine is targeted. For most of the drugs what we discuss, human is the drug destination. Drug category can be defined as major classification of the drug. For example, an antihistaminic or an antipyretic or anti anginal or pain killer, anti-inflammatory or so. Friso Gold 3 Anatomical Therapeutic Chemical codes: A medicine is classified depending on the organ or system it acts [Anatomical], based on what result it gives on what disease, symptom [Therapeutical], based on chemical composition [Chemical]. It is called as ATC code. The code is based on Active ingredients of the medicine. A medicine can have different codes as sometimes it acts on different organs for different indications. Same way, different brands with same active ingredients and same indications can have same ATC code. V06DB - Fat, carbohydrates, proteins, minerals, vitamins, combinations Friso Gold 3 pharmaceutical companies: Pharmaceutical companies are drug manufacturing companies that help in complete development of the drug from the background research to formation, clinical trials, release of the drug into the market and marketing of the drug. Researchers are the persons who are responsible for the scientific research and is responsible for all the background clinical trials that resulted in the development of the drug. Dutch Lady Milk Industries Dailymed."FOLIC ACID INJECTION, SOLUTION [FRESENIUS KABI USA, LLC]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018). Dailymed."SELENIUM INJECTION, SOLUTION [AMERICAN REGENT, INC.]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018). Can i drive or operate heavy machine after consuming Friso Gold 3? Depending on the reaction of the Friso Gold 3 after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Friso Gold 3 not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations. Is Friso Gold 3 addictive or habit forming? sDrugs.com conducted a study on Friso Gold 3, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Friso Gold 3 consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.
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The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. The reader should not assume that the information is accurate and complete. Notice of Exempt Offering of Securities hours per response: 4.00 1. Issuer's Identity CIK (Filer ID Number) Previous Names X None X Limited Liability Company General Partnership Other (Specify) Name of Issuer Kick Foods, LLC Jurisdiction of Incorporation/Organization Year of Incorporation/Organization Over Five Years Ago X Within Last Five Years (Specify Year) 2012 Yet to Be Formed 2. Principal Place of Business and Contact Information 1906 13TH STREET SUITE 304 State/Province/Country Phone Number of Issuer BOULDER COLORADO 80302 720-287-1361 3. Related Persons Goldman Andrew Boulder COLORADO 80302 Executive Officer X Director Promoter Clarification of Response (if Necessary): Shell Ross Margolis Simeon X Executive Officer Director Promoter 4. Industry Group Pooled Investment Fund Is the issuer registered as an investment company under the Investment Company Act of 1940? Other Banking & Financial Services Hospitals & Physicians REITS & Finance Lodging & Conventions Tourism & Travel Services 5. Issuer Size Revenue Range Aggregate Net Asset Value Range No Revenues No Aggregate Net Asset Value $1 - $1,000,000 $1 - $5,000,000 $1,000,001 - $5,000,000 $5,000,001 - $25,000,000 $5,000,001 - $25,000,000 $25,000,001 - $50,000,000 $25,000,001 - $100,000,000 $50,000,001 - $100,000,000 Over $100,000,000 Over $100,000,000 X Decline to Disclose Decline to Disclose Not Applicable Not Applicable 6. Federal Exemption(s) and Exclusion(s) Claimed (select all that apply) Rule 504(b)(1) (not (i), (ii) or (iii)) Rule 505 Rule 504 (b)(1)(i) X Rule 506 Rule 504 (b)(1)(ii) Securities Act Section 4(5) Rule 504 (b)(1)(iii) Investment Company Act Section 3(c) Section 3(c)(1) Section 3(c)(9) Section 3(c)(2) Section 3(c)(10) Section 3(c)(7) 7. Type of Filing X New Notice Date of First Sale 2013-01-09 First Sale Yet to Occur 8. Duration of Offering Does the Issuer intend this offering to last more than one year? Yes X No 9. Type(s) of Securities Offered (select all that apply) Equity Pooled Investment Fund Interests X Debt Tenant-in-Common Securities Option, Warrant or Other Right to Acquire Another Security Mineral Property Securities Security to be Acquired Upon Exercise of Option, Warrant or Other Right to Acquire Security Other (describe) 10. Business Combination Transaction Is this offering being made in connection with a business combination transaction, such as a merger, acquisition or exchange offer? 11. Minimum Investment Minimum investment accepted from any outside investor $25,000 USD 12. Sales Compensation Recipient CRD Number X None (Associated) Broker or Dealer X None (Associated) Broker or Dealer CRD Number X None City State/Province/Country ZIP/Postal Code State(s) of Solicitation (select all that apply) Check “All States” or check individual States All States Foreign/non-US 13. Offering and Sales Amounts Total Offering Amount $500,000 USD or Indefinite Total Amount Sold $25,000 USD Total Remaining to be Sold $475,000 USD 14. Investors Select if securities in the offering have been or may be sold to persons who do not qualify as accredited investors, and enter the number of such non-accredited investors who already have invested in the offering. Regardless of whether securities in the offering have been or may be sold to persons who do not qualify as accredited investors, enter the total number of investors who already have invested in the offering: 15. Sales Commissions & Finder's Fees Expenses Provide separately the amounts of sales commissions and finders fees expenses, if any. If the amount of an expenditure is not known, provide an estimate and check the box next to the amount. Sales Commissions $0 USD Finders' Fees $0 USD 16. Use of Proceeds Provide the amount of the gross proceeds of the offering that has been or is proposed to be used for payments to any of the persons required to be named as executive officers, directors or promoters in response to Item 3 above. If the amount is unknown, provide an estimate and check the box next to the amount. Proceeds to be used primarily for general corporate purposes, a portion of which may be used to compensate officers and repay indebtedness to affiliates. Signature and Submission Please verify the information you have entered and review the Terms of Submission below before signing and clicking SUBMIT below to file this notice. In submitting this notice, each issuer named above is: Notifying the SEC and/or each State in which this notice is filed of the offering of securities described and undertaking to furnish them, upon written request, in the accordance with applicable law, the information furnished to offerees.* Irrevocably appointing each of the Secretary of the SEC and, the Securities Administrator or other legally designated officer of the State in which the issuer maintains its principal place of business and any State in which this notice is filed, as its agents for service of process, and agreeing that these persons may accept service on its behalf, of any notice, process or pleading, and further agreeing that such service may be made by registered or certified mail, in any Federal or state action, administrative proceeding, or arbitration brought against the issuer in any place subject to the jurisdiction of the United States, if the action, proceeding or arbitration (a) arises out of any activity in connection with the offering of securities that is the subject of this notice, and (b) is founded, directly or indirectly, upon the provisions of: (i) the Securities Act of 1933, the Securities Exchange Act of 1934, the Trust Indenture Act of 1939, the Investment Company Act of 1940, or the Investment Advisers Act of 1940, or any rule or regulation under any of these statutes, or (ii) the laws of the State in which the issuer maintains its principal place of business or any State in which this notice is filed. Certifying that, if the issuer is claiming a Rule 505 exemption, the issuer is not disqualified from relying on Rule 505 for one of the reasons stated in Rule 505(b)(2)(iii). Each Issuer identified above has read this notice, knows the contents to be true, and has duly caused this notice to be signed on its behalf by the undersigned duly authorized person. For signature, type in the signer's name or other letters or characters adopted or authorized as the signer's signature. Name of Signer Kick Foods, LLC /s/ Andrew Goldstein Andrew Goldstein Manager 2013-01-10 * This undertaking does not affect any limits Section 102(a) of the National Securities Markets Improvement Act of 1996 ("NSMIA") [Pub. L. No. 104-290, 110 Stat. 3416 (Oct. 11, 1996)] imposes on the ability of States to require information. As a result, if the securities that are the subject of this Form D are "covered securities" for purposes of NSMIA, whether in all instances or due to the nature of the offering that is the subject of this Form D, States cannot routinely require offering materials under this undertaking or otherwise and can require offering materials only to the extent NSMIA permits them to do so under NSMIA's preservation of their anti-fraud authority.
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Shirt with granddad collar in parachute cotton Home — Shop — Shirts — Shirt with granddad collar — Shirt with granddad collar in parachute cotton Shipping, worldwide, is always free of charge, orders are always dispatched within three working days, and prices are always the same. XS S M L XL"> Shirt granddad parachute (XS) Shirt granddad parachute (S) Shirt granddad parachute (M) Shirt granddad parachute (L) Shirt granddad parachute (XL) Shirt, made in London, with incredibly fine and lightweight — but also incredibly strong — cotton, plus horn buttons from the Midlands. The shirt fits true to size. The body is slim, and the sleeves taper to a very tight cuff. The mannequin is a 38 — the most standard 38 in the whole world — and is thus wearing size S. To fit chest 36 38 40 42 44 Collar 15 15½ 16 16½ 17 Pit-to-pit 19 20 21 22 23 Shoulder 17½ 18 18½ 19 19½ Sleeve from side-neck 31½ 32 32½ 33 33½ Back length 29½ 30 30½ 31 31½ The shirt is made with cotton, and so may be cleaned as any shirt — which is to say, gently, and at no more than 30ºc either by hand or in the washing machine. Things last longer the better you look after them, and so things like tumble-dryers should be avoided at all costs. The shirt is intended to be worn tucked or untucked. Either. That's the whole idea. It has a fitted shape, so tucked in, it rolls tidily into trousers — but it is also casual, so when untucked it won't look like you're wearing an office shirt. Length is standard: falling a few inches below the belt-line on most people. The shirt has a "granddad collar" — which is to say, a collar stand, but no actual collar. Quite why it is named for the father of a mother or father is unknown, but it is something that can be made to look smart or casual, depending largely upon whether the top button is fastened or, indeed, unfastened. The shirt has a front of six horn buttons — each of them, in their own natural way, different from one to the next. Meanwhile, every significant seam on the shirt is what's known as a single-needle, lock-stitch, French seam. They take twice as long as standard seams, but look nicer, wear better, and last longer. The shirt has a chest pocket, with a slim pencil compartment, established with a long bar-tack. Such bar-tacks also appear at the top corners of the pocket, making it reassuringly strong. The cuffs of the shirt are very tight, and they fasten with a single button. The corner of them is gently curved, echoing the collar. The man that makes the cloth says, "It is used for parachutes and ejector seats in fighter planes. The reason it shines is that it is made from the finest Egyptian cotton, which is mercerised, like sewing thread, which also makes it very strong." It is very lightweight, similar to summer linen: somewhat see-through, therefore. As worn The gent here is 6'1", more or less 12 stone, and is as standard a 38 chest as you could hope to meet. The shirt he's wearing here, then, is a size S. Makers of The shirt is made by a shirt-maker in north London. They make shirts and only shirts all day, every day, and so have developed something of a knack for it. They make with time-consuming but strong single-needle lock-stitch seams, and with an out-of-vogue dedication to older "how shirts used to be made" contraptions. The cloth is woven by a mill in east Lancashire: in a region of the country which was once red-brick cotton-mill chimneys as far as the eye could see. More or less the last of its kind, the mill has forgotten more about cotton than most will ever know — a fact born out by the quality of its work. The horn buttons were cut, shaped, and polished by the last such factory in Britain (now defunct). It was part of a tradition in the Midlands first linked to the meat industry of the 18th century. "It is no easy task," said William Hutton in 1780, "to enumerate the infinite diversity of buttons here in Birmingham." So they say Some words to tell you about the shirts I just received. They are simply beautiful and amazing with a great manufacturing quality. And very comfortable to wear. This chap, in France, purchased a shirt in merino wool and a shirt in cotton in March 2019. Just a quick message to say I picked up the shirt from the post office today and all I can say is: wow. The material is unlike any I have felt before: you have surpassed yourselves with this one! An incredible shirt. I'm extremely pleased with it. Thanks for the recommendation. I think it may well be the most comfortable piece of clothing I've ever worn. This gentleman, living in Finland, picked up the shirt in superfine merino in March 2019. I have spent the day speculating on which descriptive superlative to apply to the shirt that has arrived safely here — and I think delightful is the best word. But wonderful and beautiful apply as well. And the cloth itself is amazing. Kind words from a kind lady in Denmark, who purchased a shirt in superfine merino hopsack in March 2019. I’ve been using this shirt a lot, and I must say it’s outstanding, I really like it. The details in the workmanship are truly amazing, from the stitching to how well the buttons are sewn on. It makes me value the whole garment. Spoken by a gent who purchased the shirt in desert cotton in the summer of 2017. I just received my shirt, and I absolutely love it. It makes me wonder why I waited so long to give your wares a try. I will almost certainly be sending more business your way in the future. Thanks very much for the fast shipping as well. Kind words from a gentleman who bought the shirt in desert cotton back in March 2017. I don't know if I just got lucky or if you folks really know how to make your shirts (I'm inclined to believe the latter) but this is the perfect compromise between freedom of movement and a slim fit in the chest and the shoulders. So emailed a man in response to the oxford shirt he purchased back in October 2014. I received the shirts and they're all very impressive. Especially the desert cotton was a pleasant surprise, definitely something that has to be seen in person. The fit is spot on as well. Now I know my size I will definitely be ordering again. Thanks for the wonderful transaction. This chap purchased three shirts, in three cloths, in August 2017. I just received the shirt this afternoon. Worth waiting for it. The cloth is soft; the cut not too slim: a perfect casual shirt. As said by a man in France on the second day of the year 2016. Wow — it's just beautiful. It is so, so lovely. I'm thrilled. A lady said this on buying a desert cotton shirt for her better half, Christmas 2016. Just writing to say "thank you" for the delivery of the [trousers and] shirt. I deeply appreciate the thought and effort that goes into creating the garments. I look forward to being a customer of yours for many more years to come. Nice words by a man back in October 2015. The workshop is small. Rather dark. Tricky to find even when half a yard away from it. Still, the workshop is home, and is open to all for looking at, trying on, and buying garments. Look out for the off-white front of the first workshop in the gated row just off Boundary Street, and step on inside. More S.E.H Kelly 1 Cleve Workshops Boundary Street E2 7JD Monday 11—6 Tuesday — Wednesday — Thursday — Friday — Saturday — Please email info@sehkelly.com day or night. There's Twitter and Instagram and Facebook. S.E.H KELLY © 2018
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EVOLUTION Of The Artist "I grew up visiting natural history museums. Within the stillness, I found a rich source of wonder and imagining and the link between these visits and my work is plain to see." Shauna Richardson has completely turned the art of crochet on its head, her work defying expectations of the craft. Inspired by a love of natural history, Richardson's work demonstrates an eye for detail and the academic study of natural forms. Her beautifully crafted life-size crochet animal sculptures are instantly recognisable, as is her Crochetdermy technique. Crochetdermy is a term invented by Richardson herself and translates to "Crochet-skin" while also hinting at "taxidermy", which her work resembles at a distance. Richardson produces her Crochetdermy animals using just one simple crochet stitch, worked in different directions to highlight anatomy, to create animal ‘skin’ directly onto a rigid form. This autumn, the Horniman Museum in London will be displaying some of Richardson's work in an exciting and illuminating exhibition: EVOLUTION of The Artist and The Exhibited Works. Part natural history, part anthropology, part story-telling, this exhibition will feature family trees, graphs, diagrams and, naturally, Richardson's realistic life-size Crochetdermy animals. Richardson's own life and development as an artist will be on display, and visitors will be able to chart her inherited traits, skills learned and adaptation to the environment as if she were one of the natural history species herself. "Within natural history collections we find all too many species now tragically extinct but without this visual reminder, perhaps people would forget about conservation." Shauna Richardson EVOLUTION of The Artist and The Exhibited Works takes place from 29 September 2018 until 17 March 2019. www.shaunarichardson.com Win An Arquelia Blouse From Casilda Mut Win An Angela Damman Bag Natalia Goncharova Catching Up With Lora Avedian
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Pisces (Fishes) The Fishes are an old constellation. They represent Venus and her son, leaping into the sea and transforming themselves into fishes to escape from the monster Typhon. The fishes are tied together with their tails, where the star α Piscium marks the knot. The Fishes contain the Vernal (Spring) Equinox. Every year, the sun moves from the southern hemisphere to the northern hemisphere while being located in Pisces. This happens around March 20, and it marks the beginning of Spring in the northern hemisphere. In ancient times (some 2500 years ago), the spring equinox was located in the constellation Ram. Hence, this equinox is also known as First Point of Aries. This constellation belongs to the zodiac. Its time of the year is between February 20 and March 20. This constellation does not belong to the zodiac. It's brightest star is η Piscium. Neighboring constellations are Pegasus, Aquarius, Cetus, Aries, Triangulum, and Andromeda. Have a look at our full list of all constellations. Latin name: Pisces (Psc) English name: Fishes Abbreviation: Psc Zodiac: February 20 - March 20 Brightest star: η Piscium Historic illustration of the Fishes in Urania's Mirror. Objects in Fishes M74 (NGC 628) a spiral galaxy in the constellation Fishes Image credit: NASA, ESA, and The Hubble Heritage Team (STScI/AURA). a galaxy in the constellation Fishes Image credit: Adam Block/Mount Lemmon SkyCenter/University of Arizona A few stars named in Fishes A few free stars in Fishes Name a star in Fishes
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Mechanical/Mechatronics April 1, 2012 | Mechanical & Fluid Systems Stemless Ball Valve Potential applications include hazardous fluids and chemicals, and where fugitive emissions from valves are a concern. Lyndon B. Johnson Space Center, Houston, Texas This invention utilizes a new method of opening and closing a ball valve. Instead of rotating the ball with a perpendicular stem (as is the case with standard ball valves), the ball is rotated around a fixed axis by two guide pins. This innovation eliminates the leak point that is present in all standard ball valves due to the penetration of an actuation stem through the valve body. The rotating venturi ramp of the original VOST design is replaced in the Stemless Ball Valve by a rotating, non-venturi gate. The VOST (Venturi Off-Set-Technology) valve has been developed for commercial applications. The standard version of the valve consists of an off-set venturi flow path through the valve. This path is split at the narrowest portion of the venturi, allowing the section upstream from the venturi to be rotated. As this rotation takes place, the venturi becomes restricted as one face rotates with respect to the other, eventually closing off the flow path. A springloaded seal made of resilient material is embedded in the upstream face of the valve, making a leak-proof seal between the faces; thus a valve is formed. The spring-loaded lip seal is the only seal that can provide a class six, or “bubbletight,” seal against the opposite face of the valve. Tearing action of the seal by high-velocity gas on this early design required relocation of the seal to the downstream face of the valve. In the “stemless” embodiment of this valve, inner and outer magnetic cartridges are employed to transfer mechanical torque from the outside of the valve to the inside without the use of a stem. This eliminates the leak path caused by the valve stems in standard valves because the stems penetrate through the bodies of these valves. This design requires high precision during assembly for proper performance of the face seal. Slight variations in tolerances result in unacceptable seal performance. An effort was made to replace this design with a less demanding arrangement of component parts. A rotating gate was proposed to be installed between the two faces of the valve. This gate would rotate in and out of the flow path of the venturi, opening and closing the valve. Although this new gate design would require a seal on both sides of the gate, it would eliminate the requirement of rotating the entire downstream side of the valve. This would simplify the valve and allow for larger tolerances for proper performance. Magnetic cartridges would again be used to actuate the valve in a stemless design. A MagBall concept replaces the rotating gate with a rotating ball. The ball does not rotate lock-step with the magnetic cartridge as the rotating gate did. Instead, the torque has a more complex rotation that allows the ball to go from fully open to fully closed. Valves based on this concept are similar to standard ball valves, but they do not require an actuation stem as do other standard ball valves. Instead, this valve rotates the ball around a fixed axis by means of two guide pins. The two pins are guided by concentric grooves that interlock with the inner magnetic cartridge of the valve. This design is suited for magnetic actuation, and provides a leak-proof valve that can be used for hazardous gases and fluids. The distinct advantages that this new design provides over previous VOST designs are the following: The passageway through the valve no longer has to be off-set as required by the rotating gate design. Instead, it can be machined through the center of the valve, using conventional boring techniques, and avoiding costly wire EDM (electrical discharge machining). The cross-sectional area of the passage through the ball is nearly twice the area provided by the hole in the rotating gate. Resistance to the fluid flow has been reduced by 40%. This is equivalent to gaining the advantage of the next pipe size larger without increasing the exterior size of the valve. The off-set venturi is no longer required for the best performance of the valve. This means that the previous minimum length requirements of the venturi are no longer necessary. The valve can be shortened to meet ASME flange-to-flange dimensions in the 4-in. (≈10-cm) and larger sizes without increasing the resistance to flow. Rotational requirements have been reduced from 180° to 90°. The valve can be actuated by standard quarter-turn actuators (without step-up gearing). This is the same type of actuation used with all ball, plug, and butterfly valves. This work was done by Robert K. Burgess of Big Horn Valve, and David Yakos and Bryan Walthall of Salient Technologies for Johnson Space Center. For further information, contact the JSC Innovation Partnerships Office at (281) 483-3809. In accordance with Public Law 96-517, the contractor has elected to retain title to this invention. Inquiries concerning rights for its commercial use should be addressed to: Robert K. Burgess, CEO Big Horn Valve, Inc. 1664 Terra Ave., #5 Sheridan, WY 82801 Phone No.: (307) 672-0968 MSC-24602-1
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Facebook's newest record: 2 billion users By Michelle Fitzsimmons 2017-06-27T22:48:44.177Z Internet Only 5 billion to go Facebook announced today it's reached a major milestone: it now has 2 billion monthly users. The social network was on the cusp of the double-billion mark for several months, and today CEO Mark Zuckerberg made it official in - what else - a Facebook post. "As of this morning, the Facebook community is now officially 2 billion people!" he wrote. "We're making progress connecting the world, and now let's bring the world closer together. It's an honor to be on this journey with you." To put the figure in perspective, Earth's entire population is 7.3 billion. Twitter has 313 million monthly users, while Instagram, which is owned by Facebook, has 700 million. WhatsApp, another Facebook property, counts over 1 billion users on its platform. And a little factoid dug up by TechRadar Senior Mobile & Buying Guides Editor Matt Swider: If this were 1927, 100% of the world's population would have Facebook. Getting to the next two billion Facebook was launched in 2004 and since then it's been on a meteoric rise that not only encompasses 2 billion users around the globe but also different products. These include the aforementioned social and chat platforms as well as the Oculus Rift virtual reality headset and various internet connectivity projects. Zuckerberg last week announced Facebook has revised its mission statement, centering the company's focus on building community. Whereas before its mission statement had to do with sharing and connecting, it now reads "give people the power to build community and bring the world closer together." Building community and bringing the world closer together goes further than helping people communicate with one another. Rather, Zuckerberg's vision is for Facebook to be a platform for people to unite around things they care about. Facebook internet-beaming drone Aquila It's a lofty goal, and Facebook is still a company that must make money, which it does largely through advertising dollars. It may be cynical, but by connecting people through various communities, Facebook can also serve advertisements to these groups more readily. Getting to the next 2 billion users will be a different type of challenge for Facebook. Most of the internet-connected world knows about Facebook already, so the company will have to deliver internet to more remote places with less infrastructure and less robust technology. (This is where Facebook projects like internet beaming drone airplanes come in, by the way.) Still, it took Facebook five years to go from 1 billion to 2 billion, and the firm is actively developing new ways for users to connect not just on the platform, but the web at large. And with Zuckerberg already stating he wants 5 billion people on Facebook by 2030, the next two may be closer than we think. Here's your primer to Amazon Prime Day 2017 See more Internet news Teamgroup 1TB SSD is now the cheapest on the planet Leak suggests Intel 10-core Comet Lake CPU could beat AMD Ryzen 9 3900X iPhone 12 could finally see Apple drop the notch The best Android apps to download in 2019
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Charles, hands-on grandfather, seen with Prince Louis in new Royal photo Prince Louis grabs the hand of his grandfather Credit: Chris Jackson / Getty Images Handout via Buckingham Palac 8 November 2018 • 10:03pm Duke of Sussex Prince Charles has been photographed with his grandson Louis and the Duchess of Cambridge in a newly-released image. The photo was released by Buckingham Palace to coincide with this evening's BBC One documentary, Prince, Son and Heir. In the programme, the Duke of Cambridge spoke of his hopes that the Prince of Wales will spend more time with his grandchildren as he reaches the age of 70, as he and his brother celebrated the landmark birthday with a moving public tribute. The Duke, whose children Prince George, Princess Charlotte and Prince Louis are the Prince’s only grandchildren until the arrival of the Sussex baby in the spring, said his father was “brilliant” with all three, expressing... Register for free to read this article, or log in to your Telegraph account
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How far will the UK’s most popular cars get on a single tank of fuel? Published: 10:17 am May 15, 2019 Fuel prices are a constant source of worry for drivers and recent months have seen a series of rises adding to their burden. According to the RAC, petrol prices jumped more than 5p per litre in April – the worst rise in nearly 20 years – and there is little sign of costs dropping any time soon. It’s important, then to make sure you get the most out of every tankful and new research has revealed which of Britain’s most popular cars offer drivers the best value. Focus on the prize The investigation pitted the UK’s ten best-selling cars against each other to see which could travel the greatest distance on a single tank of petrol. It found that the Ford Focus could not only travel furthest on its 52-litre tank but that it also trumped every other model when it came to cost per mile. The Ford Focus was found to have the longest range and over the lowest cost per mile. (Picture: Shutterstock) According to the data from Euro Car Parts, the Focus is capable of covering 1,112.69 miles on a single fill-up, at a cost of £66.75. Not far behind it are the VW Golf and Audi A3, which can both achieve 1,046.12 miles at a cost of £70.40. The study compared data for the 10 most popular cars based on the number of new registrations and second-hand sales recorded by the Society of Motor Manufacturers and Traders. How far a car can travel on a tankful is obviously partly down to the size of the fuel tank, with the tested cars’ capacity ranging from 40 to 60 litres. However, across their most popular versions, the Focus still managed to cover more ground than the BMW 3 Series, VW Golf and Audi A3, all of which have larger tanks. Based on the number of miles covered and the cost of filling the tank, the Focus costs 7.1p per mile to run, ahead of the VW Polo (7.6p) and Ford Fiesta (7.8p). 10 most popular cars by maximum distance travelled on one tankful # Model Distance (miles) Tank Size (L) Cost to Fill 1 Ford Focus 1,112.69 52 £66.75 2 VW Golf 1,046.12 55 £70.40 3 Audi A3 1,046.12 55 £70.40 4 BMW 3 Series 1,014.42 60 £76.80 5 Vauxhall Astra 874.94 48 £61.44 6 Renault Clio 855.92 45 £57.60 7 Ford Fiesta 821.05 42 £53.76 8 VW Polo 803.08 40 £51.20 9 MINI 639.30 44 £56.32 10 Vauxhall Corsa 606.28 45 £57.60 The study used the average petrol price of £1.28 per litre as recorded by RAC Fuel Watch for April and calculated the maximum distance using the official fuel tank capacity and maximum combined miles per gallon figures from the car maker.
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<iframe width="640" height="360" frameborder="0" allowfullscreen="allowfullscreen" src="https://www.theatlantic.com/video/iframe/414178/"></iframe> http://www.theatlantic.com/video/index/414178/young-gay-hiv-positive-and-a-pastor/ The Atlantic Selects Young, Gay, HIV-Positive—and a Pastor Nov 09, 2015 | 764 videos Video by Carter McCall Dennis Massenberg says that he used to be a "church hopper," someone who bounced from congregation to congregation—he stayed when things were good and he consented to the theology, before inevitably departing for somewhere else. For a long time, he believed that homosexuality could be changed, so he fervently denied his proclivities. Now, Massenberg is the pastor of a church that he started, one that is intent on accepting gay people and giving them a place to worship. "I'm preaching a gospel that's contrary to popular belief," he says in this moving documentary, Purpose in the Pulpit, by Carter McCall. "I became an activist." Author: Nadine Ajaka A showcase of cinematic short documentary films, curated by The Atlantic. Email me when the next episode is live. The Horrors of ICE’s ‘Trans Pod’ Atlantic Documentaries Life in the World’s Fastest-Shrinking Country Ahead of 2020, Beware the Deepfake A Baffling Murder Case. An Unimaginable Tragedy. The Atlantic Argument What Does It Mean to Support ‘Free College’? How Do We Solve the Problem of Predators? Visual Histories Atlantic Interviews School Myths Sponsor Content:
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Keeping the £ local Gruffalo fun at Theatre Severn, Shrewsbury I look forward to half term in Shrewsbury so I can spend some valuable time with my two little ones. But as all mums know, keeping them occupied, especially at their ages, can require some forward planning, so I was so thrilled to see a stage performance of The Gruffalo on at Theatre Severn. I jumped at the chance to take my eldest, thinking it might be a bit too involved for my younger daughter to follow. The show came to our stage direct from a smash hit West End Season, and had been adapted to the musical stage from the award-winning Tall Stories picture book by Children's Laureate Julia Donaldson and Axel Scheffler. The Gruffalo was voted the nation's number one bedtime story by BBC Radio 2 listeners and has been performed to well over a million people the world over and has even hit the small screens in a star-studded TV animation. The stage show was a little different to what I had anticipated, but that didn’t stop Maddie, the packed audience and myself having a great time. We also met a wheeler-dealer Fox, an eccentric old Owl and a maraca-shaking, party mad snake – all character depictions were true to the original story. The tale goes that Mouse can scare these hungry animals away with tall stories of the terrifying Gruffalo, but know one, Mouse included, could have predicted what happens when he came face to face with the very creature he imagined. Actor animals The show was billed for children and ‘their grown ups’ from three upwards. I expected the characters to be fully dressed in outfits depicting the animals, so you wouldn’t see the actors. But instead, the actors were cleverly dressed as the animals – just giving a suggestion of the creature they were playing. So the actor portraying the snake for example, was dressed in rather cool and magical coloured attire, but so you could still see he was a man and follow his actions and movements. I’m not sure my youngest would have followed this, but being a fan of the story, my eldest really got into it and it didn’t phase her at all. There were lots of laughs and the scary wasn’t too scary. The songs and music were really enjoyable too and I could see from all the other children around me who were enthralled also that everyone had a good time. As previous reviews in the nationals have said, it really was charming. Theatre Severn has a varied programme but there is always something for your little ones. Make sure you check out what’s on via the Theatre Severn website Watch The Gruffalo stage show trailer online at www.gruffalolive.com. Emma R I'm one half of thebestof Shrewsbury, this lovely website (and more) we set up in 2006. If you know a great business that needs shouting about on our site, newsletters and social media channels, email...
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Mar 20 Extreme Makeover: Design Edition Sometimes companies can be slow to update their look and outdated branding (i.e. in the form of logos, graphics, websites, posters, apps, etc.) can hurt a company’s credibility. Branding is important (see our previous posts on branding evolution and brandless trends) because it is ultimately the first tangible aspect of a company for consumers to recognize. While some franchises may take a long time to change their designs, here are a few that have recently realized that their designs needed a refresher. In our opinion, it was worth the wait... 1. Rotten Tomatoes Rotten Tomatoes, a movie rating website, was founded in 1998; however, it’s been over a decade since their brand has received any design attention. In 2001, the “Rotten Tomato” logo was set in a bright yellow hue, embolden with a black background that outlined the letters. This month, the color and shadow effect was dropped, leaving us with a crisp, red design. The letters are now flat, but that doesn’t mean that they are not dynamic. The o’s of the new design are also updated: one is in the shape of a cut-open tomato while the other looks like a full tomato with a vine on top. According to Design Week, “Emily Oberman has given TV and film review website Rotten Tomatoes a new logo, icons, and colour palette, which look to ‘modernise’ it while retaining its ‘familiar elements.’” Last year, Skype’s site graphics got a makeover. The old design included the word “skype” in white, lower-case letters with a puffy, cloud-like blue outline surrounding the text. Now, the design, much like Rotten Tomatoes, is simply in blue a la the Microsoft font. This is to associate the video chat product with Microsoft and the association works. Meanwhile, the Skype app logo has mostly stayed the same over time. 3. Subway There is definitely a trend in logos nowadays of dropping the emphasized background surrounding a text. Subway, one of the United States’ most popular deli sandwich chains, is no stranger to this strategy. Their logo a few years ago went from angled letters spelling “Subway” in white and yellow with a green shadow background, to a cleaner font showcasing the company’s colors by setting the prefix “sub” in yellow and the suffix “way” in green. Subway is working to incorporate its new logo into the stores themselves as well. According to Design Week, newly designed stores will highlight Subway’s freshness by showcasing more vegetable-like colors in the stores and through their new computer screen ordering system slowly being implemented nationally. This is Subway’s way of promoting healthy eating options through their color choices while updating their look (you can read more about color psychology theories here) . 4. Pepsi In 1998, the Pepsi logo incorporated a blue background with the word “Pepsi” superimposed over their signature red, white, and blue, circle. Designers in 2011 changed that and now the logo has similar features, but ultimately looks cleaner and positively minimalistic. The circle is on the left with the “Pepsi” letters to its right in white. The letters are half the size of the 1998 version. Additionally, according to Graphic Design USA, Pepsi just launched a sparkling water beverage called Bubly in a similar font to showcase unity between the Pepsi products. 5. MasterCard MasterCard’s logo recently went through a complete minimalist transformation while still remaining familiar to users. What remains the same in both renditions is a red circle overlapping a yellow-orange colored circle; but that’s pretty much the only similarity. The overlap of the circles in the old logo is jagged while the new version is transparent with the middle section colored in orange. The word “mastercard” has moved from the middle of the circles to underneath them and the font has drastically changed as well, in a style that’s similar to the examples above. Adweek quoted MasterCard CEO, Raja Rajamannar, on the new design. He stated, “The MasterCard logo is recognized universally...There are 2.2 billion cards that carry the MasterCard logo. There are tens of millions of merchants worldwide that carry the MasterCard logo at the point of sale. The key for us is the equity in that logo--we have to leverage that going into the future.” One thing is clear through all of these examples: shadows and highlights are out. Sleek and skinny fonts that stand alone are in. And a sense of familiarity needs to remain constant when updating a brand’s look. Curious about other design trends for 2018? Check out our list of predictions here. What other logos in your opinion have made complete and necessarily transformations recently? Comment below. Apr 5 Turn Up the Volume: 5 Podcasts for Individuals in Creative Roles Mar 14 7 Things to Never Say to a Designer
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Arts Explores: Well-equipped BVAC Digital Arts Lab by Sophia Siu | 5/9/16 5:01pm The digital arts lab has some of the most powerful graphic design and video editing software available to students. by Seamore Zhu / The Dartmouth Surrounded by glass walls, the digital arts lab can be found in the middle of the first floor of the Black Family Visual Arts Center. The lab is a space in which students can create digital art using some of the most powerful graphic design and video editing software available today. “I recommend anyone who wants to learn how to edit film, make a poster — just any creative thing they have in mind — that’s the best digital resource that Dartmouth has for that sort of stuff,” Matt Rossi ’16 said. The digital lab houses 11 computers in a multi-use room that is currently set up for seminar classes and workshops, as well as lectures. The most commonly-used software package available in the lab is Adobe Creative Cloud, a collection of software that includes After Effects, Photoshop and Premiere Pro. Chris Ivanyi, the digital lab specialist, envisions the lab becoming a vibrant space in which all members of the Dartmouth community can experiment with and learn about different digital arts software. “It’s always my hope that it becomes this third space — home, work and this place — where people can come in and just create cool things with the tools that we have,” Ivanyi said. Several classes have been held in the lab, including professor Karolina Kawiaka’s Studio Art 17 “Digital Drawing” class, as well as professor Jeffrey Ruoff’s Film Studies 36 “Experimental Filmmaking” class. Only through key card access can studio art and film and media studies majors access the lab, but Ivanyi allows any student who wants to learn about the software or work on a project to use the lab. “I have this open door policy,” Ivanyi said. “If someone has a particular project they want to work on, with or without my help, they can come back anytime.” Rossi also noted how Ivanyi welcomes all students to the space. “If Chris knows that you’re pretty passionate about what you’re doing, and you ask him, he’s very laid back about it,” he said. In order to make the lab and the technology more accessible to students, Ivanyi also organizes and holds weekly workshops that allow students to learn about and experiment with different software. These workshops are designed to cater both to people who are already familiar with the software and those who have never touched the programs. “People can get a little bit of a hands-on and not be so intimidated,” Ivanyi said. “Some folks already know this stuff already, but we have a lot of people come through who haven’t even touched Illustrator or Photoshop.” Ivanyi holds make-up workshops on Friday afternoons for people who missed them earlier in the week. In addition to workshops, Ivanyi invites professors from other departments to dicuss how they use software in their courses. Last term, Ivanyi invited guest artists, including local filmmakers and computer science professor Patricia Hannaway who teaches animation courses, to demonstrate their use of the digital programs. Although Rossi has not taken a class that required the use of the digital lab, he has used the lab for several personal projects. “Chris was really welcoming,” Rossi said. “I basically told him what I wanted to do, and he got me started on Premiere Pro.” He recalled that after getting an introduction through Ivanyi, he was able to move on to more complicated techniques, such as “color correcting.” Kyle Kaplan, a second year masters student in digital musics, also found the lab’s software and hardware to be invaluable resources. “The computers are many times faster than what I personally would have access to with my own laptop,” he said. Rossi also appreciated that Ivanyi himself constantly learns as he teaches students about the software, making the interaction more like a conversation than a lecture. “The environment feels less like a lecture world, where all this information is being thrown at you,” Rossi said. “It’s more like a collaboration between whoever is working there and Chris.” For his first project using the lab, Rossi edited video footage he took with a drone flying over Dartmouth’s campus. He is currently filming a few short films as part of another personal project and plans on returning to the lab to edit his footage. Kaplan also noted that besides Ivanyi, other students working in the lab are available to provide help. “There’s a nice sense of community that it creates because you’re just in contact with people who are also doing creative video work,” Kaplan said. “There’s a nice camaraderie that gets fostered in the digital lab.” Most of the video editing for two of Kaplan’s personal projects took place in the digital lab. One of the projects, an eponymous documentary on the Taiwanese noise musician, Dino, featured an extended interview interspersed with performance footage. “[Dino] is a very compelling person, with punk rock roots that led to noise music from Taiwan’s huge cultural revolution during the ’90s right after the democratization of Taiwan,” Kaplan said. “Western influence, and with it noise music, started to penetrate the culture. He was the product of that.” After attending Ivanyi’s workshop for After Effects and Premiere Pro, Kaplan sought to explore Premiere Pro as in depth as possible for his Dino project. Ivanyi acknowledged that being the sole person running the digital lab can be a lot of work, but the benefits are greater. “There’s nothing more rewarding than to have a student come in who has never worked on this and create something amazing,” Ivanyi said. Tags: arts Review: 'Stranger Things 3' is an electric revival of the series Review: ‘Ma’ fails to be a horror film, let alone a good horror film 'Humans' by Circa to shift perspective on circus arts and emotion
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Cyclones pull away behind Wigginton By LUKE MEREDITH AMES — Freshman Lindell Wigginton poured in a season-high 28 points and Iowa State rallied to beat Northern Illinois 94-80 on Monday night for its fifth straight win. Senior Donovan Jackson added 24 points with six 3-pointers and Nick Weiler-Babb had 12 points and 11 assists for the Cyclones (5-2), who overcame depth issues to outscore the Huskies 58-42 in the second half. Iowa State certainly looked rusty after a nine-day layoff, falling behind 38-36 at halftime after letting the Huskies hit 17 of their first 31 shots. But the Cyclones opened the second half on a 26-11 run, with Wigginton hitting an off-balance 3 to push Iowa State’s lead to 10. Jackson followed with a 3 that made it 62-49. Wigginton then jumped a passing lane at the top of the key and cruised down court for a two-handed dunk and followed with an assist on a Cameron Lard dunk, pushing the Cyclones lead to 70-51. Reserves Jakolby Long (concussion) and Zoran Talley (bruised foot) sat out with injuries, leaving Iowa State with just eight available players. Long and Talley are day-to-day according to the Cyclones. Eugene German had 28 points for the Huskies (5-4). Iowa State: Wigginton’s move from point to shooting guard has freed the freshman up to attack the basket while looking to score — a valued commodity for a team without a lot of proven scorers. He has responded with 63 points in his last three games. The next question for the Cyclones will be in how they adjust once opponents start making stopping Wigginton a priority. Northern Illinois: The Huskies lost for just the second time in five games. But if they can play two halves like they did the first one on Monday, they’ll be a handful in the MAC. Iowa State hosts rival Iowa on Thursday. The Hawkeyes were blown out by Indiana on Monday, their fifth loss in six games. Northern Illinois hosts Central Connecticut State on Saturday.
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Formula 1 pre-race predictions: Japanese Grand Prix Drivers face demanding curves of Suzuka by Jason Dela Cruz | Oct 12, 2013 There\'s a certain charm about Suzuka. The old-school, figure-of-eight circuit consists of technical, fast-flowing bends. Drivers are constantly on the limit here. This track is unforgiving--drivers have to be brave to get on the throttle and tackle the curves. But make a mistake and you end up in the gravel trap rather than the tarmac run-off area where you can carry on racing. It\'s also challenging for the engineers to find the right balance. Continue reading below ↓ Demanding curves such as the \'S\' Curves, the Spoon Curve, the 130 R, the Casio Chicane and the Degner One make this circuit a favorite not only among drivers, but among fans as well. So, what will the race weekend bring, and how will we fare with our predictions? 1. Romain Grosjean will out-qualify Kimi Raikkonen. Grosjean is quick but has often been reckless. Things are registering in his head much better, and as a result are polishing his racing skills. When Grosjean gets it right, he can beat his teammate. 2. It\'s going to be a Sebastian Vettel whitewash. We have the same sentiment as Mercedes: We fear that the German can win every remaining round. With four straight wins and the unmatched performance of the RB9, it\'s hard to see otherwise. Suzuka is a high-downforce track with medium- to high-speed corners, which is the car\'s strength. What else is there to say? At least we have a good chance of scoring a point with this prediction. 3. Fernando Alonso and Raikkonen will complete the podium. Sebastian can win the title here if Fernando finishes no higher than 8th. Frankly, we don\'t see that happening and want to delay the inevitable as long as possible. Alonso and Raikkonen\'s skills always shine on tracks like Suzuka. They\'ll find the extra speed in tomorrow\'s race. 4. The Mercedes duo will be in the points, as will Nico Hulkenberg. It has been the RBR-Mercedes show come Saturday, but Mercedes\'s performance on Sunday has been hit-or-miss, thanks to the tires. This prediction will be hit-or-miss as well. The track suits the silver arrows, but we think they\'ll struggle with the black round stuff. They\'ll qualify high, but their performance will drop. As for Nico Hulkenberg, he\'s on form. And we want his point tally to continue. 5. At least three drivers will spin off. There are a number of rookies on the grid. The technicality of Suzuka will get the better of them. Catch the race tomorrow at 2pm (Philippine time). Photo from Infiniti Red Bull Racing JPN Free Practice One Free Practice Two Pos Driver (Team) Time Driver (Team) Time 1 L. Hamilton (Mercedes) 1:34.157 S. Vettel (Red Bull) 1:33.852 2 N. Rosberg (Mercedes) 1:34.487 M. Webber (Red Bull) 1:34.020 3 S. Vettel (Red Bull) 1:34.768 N. Rosberg (Mercedes) 1:34.114 4 M. Webber (Red Bull) 1:34.787 K. Raikkonen (Lotus) 1:34.202 5 F. Massa (Ferrari) 1:35.126 R. Grosjean (Lotus) 1:34.411 6 F. Alonso (Ferrari) 1:35.154 L. Hamilton (Mercedes) 1:34.442 7 R. Grosjean (Lotus) 1:35.179 D. Ricciardo (Toro Rosso) 1:34.473 8 K. Raikkonen (Lotus) 1:35.364 F. Massa (Ferrari) 1:34.698 9 S. Perez (McLaren) 1:35.450 J. Button (McLaren) 1:34.912 10 D. Ricciardo (Toro Rosso) 1:35.635 F. Alonso (Ferrari) 1:35.087 11 J. Button (McLaren) 1:35.868 E. Gutierrez (Sauber) 1:35.089 12 N. Hulkenberg (Sauber) 1:35.900 J. Verge (Toro Rosso) 1:35.109 13 J. Verge (Toro Rosso) 1:36.066 N. Hulkenberg (Sauber) 1:35.182 14 A. Sutil (Force India) 1:36.165 P. di Resta (Force India) 1:35.275 15 P. Maldonado (Williams) 1:36.178 A. Sutil (Force India) 1:35.341 16 V. Bottas (Williams) 1:36.340 S. Perez (McLaren) 1:35.709 17 P. di Resta (Force India) 1:36.399 V. Bottas (Williams) 1:36.136 18 E. Gutierrez (Sauber) 1:36.760 P. Maldonado (Williams) 1:36.722 19 H. Kovalainen (Caterham) 1:37.595 C. Pic (Caterham) 1:37.630 20 J. Bianchi (Marussia) 1:37.629 G. van der Garde (Caterham) 1:37.905 21 G. van der Garde (Caterham) 1:38.025 M. Chilton (Marussia) 1:38.121 22 M. Chilton (Marussia) 1:38.763 J. Bianchi (Marussia) No Time Man claims to have had sexual intercourse with nearly 1,000 cars View other articles about: motorsports, Sebastian Vettel, Formula 1, Formula 1 predictions, Japanese Grand Prix TRANS SPORT SHOW 2019 Buyers' Guide Get A Quote Moto Sapiens TRANS SPORT SHOW 2019 © 2019 Top Gear Philippines Sorry, no results were found for Or search for a specific car Brand / Model Below ₱500K ₱500K — ₱1M ₱1M — ₱1.5M ₱1.5M — ₱2M ₱2M — ₱3M Over ₱5M Most Viewed Cars this Week: Honda BRV Mitsubishi Adventure Isuzu MU-X Read the Story → This article originally appeared on Topgear.com. Minor edits have been made by the TopGear.com.ph editors. Retake this Poll Quiz Results Take this Quiz Again TGP Rating: Starts at ₱ We use cookies to ensure you get the best experience on Topgear.com.ph. By continued use, you agree to our privacy policy and accept our use of such cookies. Find out more here.
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Barrhed Travel Travel To Me Feb 13, 2017. Travel to me means building relationships with people you never would have met otherwise and treating them like family. It's trusting people. Specialists in small group, private custom travel in South America. Leave the tour buses behind and let us plan your vacation exactly how you’d like it. Follow our Playlist. Discover The seventh place spot goes to the 6.17pm from Glasgow Central to Edinburgh at 110%, while the 7.56am Barrhead to Glasgow Cen. The Mayfair office will also serve as a hub for bank representatives from Poland as they travel to London to secure their client base. Bank Pekao was founded in 1929, and boasts over 15,000 employees. Bill Munro, founder and chairman of Barrhead Travel received Glasgow Chamber’s Lifetime Achievement Award. Other notable winners included Premiership Experience, City Building LLP, Clyde Shopping Cent. Nothing runs like a Deere. except maybe Mounties looking to nab suspects. On Saturday, a Barrhead RCMP investigation that started as a suspicious person complaint turned into a police chase with a st. Three people are facing charges after the alleged murder of a B.C. man who vanished from the Barrhead area. Valentine Degenhardt, of Salmon Arm, B.C., had been reported missing by his common-law spous. What Are Generators For Camping Yamaha was one of the first providers of these leisure-based generators, and truly set the bar for portable camping generators. The Yamaha has long been a reliable staple for veteran campers, who continue to swear by the Yamaha brand, having used the earlier models for years of safe power generation. Hulsey State Fish Hatchery is and could have involved requiring Swiss inspectors to travel abroad to conduct compliance checks. A separate Food Sovereignty proposal aimed to underpin farmers’ salaries and ensure imported food meet. &lt;img class="styles__noscript__2rw2y" src="https://dsx.weather.com//util/image/w/ba8f6c2f-3131-49bd-9474-a75c29dd0788_815x458.jpg?v=at&w=1280&h=720&api=7db9fe61-7414-47b5-9871-e17d87b8b6a0" srcset=". And in seventh place overall is the 6.17pm from Central to Edinburgh, which runs at 110%, followed by the 7.56am Barrhead to. A missed curfew in Barrhead, Alta., resulted in the seizure of drugs, cash and a stolen semi-automatic shotgun. Barrhead RCMP arrested a man last Friday after he allegedly breached his curfew conditio. Ninth in the list is the 5.27pm Glasgow Central to Barrhead journey, and the 10th most overcrowded. Hitachi trains and £54. A Barrhead woman who helped her drug dealing killer brother move his victim’s body and clean up the bloody murder scene was put behind bars on Friday. Norma Jean McAllister, 47, was handed a four-year. THE new Barrhead Travel shop in the Oak Mall will open tomorrow. It will create six permanent jobs at the unit previously occupied by Paperbox, with a mixture of full-time and part-time positions. Sha. Globus Travel Insurance The global Spine Fixation market is valued at million US$ in 2017 and will reach million US$ by the end of 2025, growing at a CAGR of during 2018-2025. The major manufacturers covered in this report T. Premier Custom Travel is a family-owned, full-service travel agency specializing in cruises, Disney vacations and destinations worldwide. Globus Paul Parker Royal Caribbean Cruises Ltd What Are Generators For Camping Yamaha was one of the first providers of these leisure-based generators, and truly set the bar for portable camping generators. The Yamaha has long been a reliable staple for veteran campers, who continue to swear by the Yamaha brand, having used the earlier models for years of safe power generation. Many travel agents will have the benefit of selling a wider variety. Travel Leaders Group is clearly playing a scale game, and although Barrhead Travel might be an old-fashioned travel business, at. How To Get A Job Traveling Nov 18, 2014. Dreaming of a job that pays you to travel?. beach or exploring Hong Kong is a bonus but cabin crew also get generous travel benefits so you, Mar 8, 2017. Want to earn money WHILE you travel or live abroad? It's entirely possible, and EASY too. Here's how to find legitimate work A 14-year-old girl was raped after being forced into bushes outside a supermarket. The victim was going to collect her bicycle after visiting an Asda store in Barrhead, East Renfrewshire, when she was. Edition! The mighty Mini 2-in-1 PC with long battery life is here Microsoft More from The Scotsman Barrhead Travel sales soar. Previous Previous post: What Are Generators For Camping Next Next post: Tennis Holidays Portugal
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+1 (0) 800 635 8124 About Us Blog Destinations Experiences Itineraries Specials Contact Everything was unbelievable right from the beginning of our stay! Aurora 28 yrs, Belgium, Read 0 reviews » Ivory Lodge Family friendly lodge Renowned area where the Presidential Herd come to drink Facilities include Paid internet access Pool Room safe Bar Activities include Pan sits Game drives Painted Dog Conservation Centre Seasons in Zimbabwe Peak Mid Low About Ivory Lodge This family run lodge is full of character, with rooms built on stilts in a Robinson Crusoe style, offering open-aired views of the floodlit waterhole. Its location in the Hwange National Park is best known for being home to great herds of elephants who stroll past your stilted hut, and take refuge from the almighty heat at Ivory Lodge’s waterhole. The staff at Ivory Lodge will go above and beyond to make your stay as comfortable as possible, and the guides have an expert knowledge of the area. The huts are kept immaculate and the food is fantastic. With one family room, and two suites that can be converted into triples for families, this lodge is extremely accommodating of children. Ivory Lodge is set on a private concession at the edge of the renowned Hwange National Park. Ivory Lodge is easily accessible by road or from the airport, and a transfer can be arranged through the camp. June through to October is the dry season in Zimbabwe and is regarded as the best time to go as the animals congregate at the few and far between water sources. At the beginning of the season, vegetation can be relatively dense making the animals harder to spot, and the temperature at night tends to drop. However, towards the end of the season vegetation is sparser meaning wildlife spotting is at it’s absolute best. Although, nights can be hot and humid. November through to May is the green season, where rain is common especially between December and February. With vegetation at its most dense, wildlife can be harder to spot but the bush looks beautiful with plenty of wildflowers and baby animals. There are fewer visitors at this time of year, and prices are considerably reduced. It is necessary to have a visa to visit Zimbabwe. It is possible to get one upon arrival or from the Zimbabwean Embassy in London. If you choose to get one on arrival, make sure you take enough cash with you in small notes to pay for your visa at the airport. You can also apply for a visa online before travel. Visit your health professional at least 4 to 6 weeks before your trip to check whether you need any vaccinations or other preventive measures. Children of all ages welcome. 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'I WOKE UP IN HELL' Mum shares five-month agonising battle with meningitis after thinking it was a tummy bug Lucy Dixon has had a long road to recovery trying to walk again, but her son George has been her strength By Lucy Dixon Updated: 31 Aug 2018, 8:26 LUCY DIXON called the NHS helpline over “a tummy bug” – then woke up a month later in hospital. After collapsing at home, the single mum, 39, was rushed to intensive care with meningitis. Her recovery has been tough but with the love of son George, six, and the rest of her family, Lucy is battling to get back on track. The writer from Blundeston, Suffolk, tells her story. Lucy Dixon thought she had a 'tummy bug' but it ended up being meningitisCredit: Louis Wood - The Sun I opened my eyes and instantly shut them again. The fluorescent lights on the hospital ceiling sent shooting pains through my skull. I could hear my mum’s voice and feel her hand grabbing mine. I tried to ask where George was but couldn’t speak. There was a tube down my throat attached to a ventilator helping me breathe and although I could squeeze Mum’s hand, I couldn’t move much else. Lucy's road to recovery has been tough as she keeps fighting to get betterCredit: Louis Wood - The Sun Lucy collapsed at home and woke up in hospitalCredit: Collect My last memory was of calling 111 with a pounding headache, neck ache and sickness bug that wouldn’t shift. Now I thought I’d woken up in hell. My GP had said it was flu. But I collapsed getting out of bed and was taken to hospital. I spent the next month in intensive care. I’d had meningitis, leading to encephalitis and a neurological condition called transverse myelitis that damaged my spinal cord. The slightest movement was agony. Those first few days, broken up by morphine-induced sleep, consisted mainly of panicking about my son but not being able to communicate my fears. The mum said the love of her George is what kept her strongCredit: Louis Wood - The Sun Lucy cried tears of joy when her son George came to visit her in the hospitalCredit: Collect I hadn’t really grasped that I was paralysed. I’d lay awake planning how I would demand to be discharged, not realising it would be another five months before I slept in my own bed. Mum visited every day and moved into my house to look after my son. I was in no fit state to see him at first. I was still in ICU and spent most of my time crying. Mum put photos at the end of my bed. I’d stare at George’s picture, desperate to hold him and tell him I loved him — but with a sick feeling in my stomach that he’d be better off without me. Lucy was finally discharged after five months in hospitalCredit: Louis Wood - The Sun George supported his mum and stayed strong for herCredit: Collect I was later moved to an ordinary ward and George came to see me for the first time in more than a month. As soon as he skipped in I started crying, reassuring him they were happy tears. He was shy at first and it broke my heart that I must have seemed like a stranger. I couldn’t tell him everything would be all right. I didn’t know. His visits were bitter-sweet. I adored how he curled up in the hospital bed with me, but was so sad that I wasn’t the mum he was used to. After another month I was transferred to a specialist neurological rehabilitation unit, which would be my home for the next three months. Baby Kia Gott, who had her four limbs amputated after contracting a rare strain of meningitis, is set to return home The move made me realise I wouldn’t just wake up one day able to walk. I had a long journey ahead, with no guarantees. With my own room, at least I had some privacy. It was further from home, though, so I saw George just once a week. He coped so well for so long but struggled when I moved hospitals and kept asking me if I was going to die. Not being there to comfort him was hideous. After five months in hospital, I was disch-arged a few weeks ago. I cried my eyes out. I no longer think George would be better off without me and it’s surprised me how well we have all adjusted. MOST READ IN FABULOUS The signs to out for IT is vital to spot meningitis early, when treatment can save life, says Sun doctor CAROL COOPER Symptoms can be vague but most people would get some of these: Dislike of bright light Feel very ill Confusion or irritability Note that the symptoms are different in babies, and overlap with sepsis as some meningitis strains develop into this. A rash that doesn’t disappear when pressed with a glass is a late symptom, don’t wait for that before seeking treatment. If you suspect meningitis, go straight to A&E and say you think it is meningitis or sepsis. It’s unlikely I will ever be back to how I was, but I can hobble about and George is brilliant at helping. I suffer pangs of guilt that his child-hood has been altered but he seems rem-arkably chilled out. What has it taught me? You don’t know what the future holds, so make the most of every moment. 7 Health is a gift.
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A Charlie Brown Christmas The Musical For Athesists What Do They Wear At La Jolla Marriott Dancing Club United States: Fort Worth Plus, they work just as hard as flowers do to keep every room in your home as fresh as possible. Capture the classic color of our iconic hero’s look when you wear Mickey Red Lipstick by Besame. Mad. The Duke of Cornwall, his wife Camilla Parker Bowles and the Queen will Unfortunately, the full Atheist’s Guide runs over 2,000 words. this are remarkably complex by children’s entertainment standards. But, then, A Charlie Brown Christmas had the advantage of being wri. brings all your favorite characters to life — all set to the unforgettable sounds of the Vince Guaraldi musical score. Everyone is giddy with Christmas cheer, but Charlie Brown has the Yuletide blues. For many of us, A Charlie Brown Christmas. Charlie Brown. Performing the song Happiness from the musical, Chenoweth wanted to be a part of the celebration because of her history with the Peanuts ch. The iconic Peanuts special “A Charlie Brown Christmas” turns 50 this year, which ABC marked Monday night with a musical retrospective celebrating the animated tale that has become a hallmark of the ho. "A Charlie Brown Christmas" was executive produced by Lee Mendelson and created and written by Charles M. Schulz. Bill Melendez is the producer and director, and Vince Guaraldi is the music composer. Guaraldi wrote and performed the music for the first fifteen animated Peanuts specials, until his untimely death in 1976. The album, “A Charlie Brown Christmas” is the second most sold jazz album in h. “A Charlie Brown Christmas” is often characterized by the song “Christmastime is Here.” While it isn’t a core focus of this special, the song does play as background music. Snoopy’s Siblings Are Featu. When Johnny Says Goodbye To Baby Dirty Dancing Movie What Do They Wear At La Jolla Marriott Dancing Club United States: Fort Worth Plus, they work just as hard as flowers do to keep every room in your home as fresh as possible. Capture the classic color of our iconic hero’s look when you wear Mickey Red Lipstick by Besame. Mad. The Duke of and make a shambles of rehearsal for a Christmas play. Snoopy steals the scene in the comic strip, the television specials and the popular musical "You’re a Good Man, Charlie Brown." Talented mime Mar. he needs Linus’ help to discover the real meaning of Christmas. Returning for a second-year as Charlie Brown is Tyler Hentz. Tyler has appeared at MMT most recently in the ensemble of Curtains and as. Said Ms. Shannon, "I am so thankful that the court ruled in my favor and that Killeen School District efforts to ban my Charlie Brown Christmas poster. and the often profane “music” they’re plugged. Whose Line Is It Anyway Cats Will Go On As A Musical Voila! Finally, the The Princess And The Frog script is here for all you fans of the Disney musical movie. This puppy is a transcript that was painstakingly transcribed using the screenplay and/or viewings of the movie to get the dialogue. Electric Light Orchestra Alone In The Universe Play Marvel Cinematic Universe The Incredible Hulk. BLACK BOX Jazz presents A Holiday Jazz Brunch featuring music from A Charlie Brown Christmas on Sunday, December 16 at noon. For many, Christmas is not complete until they have watched Linus explain t. A Charlie Brown Christmas Live on Stage, Schulz’s timeless story of the spirit of Christmas, showcases the unforgettable music of Vince Guaraldi, performed by a three-piece ensemble on stage, as well. The music begins and you feel the crowd smiling. It’s a wonderful feeling.” A new song, “Just Like Me,” was added, at the end of Act I as a duet between Charlie Brown and Linus while they select the i. Who Wrote The Music Of Avinu Malcainu Sung By Barbra JERUSALEM (AP) – The Latest. sing at his funeral. Walden predicted the song would be the prayer “Avinu Malkeinu,” or “Our Father Our King.” Jews sing the prayer on the Day of Atonement, which falls. Flttbulh ana Tilde Avtnuci I.OKWS PITKIN Pitkin and saratota Avenuea ikii ) LOEWg alpine.7 vin irei ana emu Avinu I.OEW An atheist group is accused of waging war against Christmas by attacking an Arkansas elementary school for a field trip to see "A Charlie Brown Christmas" at a local church. The group is arguing that. Electric Light Orchestra Alone In The Universe Play Marvel Cinematic Universe The Incredible Hulk. Robert Bruce Banner was born on December 18, 1969. As he grew up from childhood, he started going by his middle name. Discover releases, reviews, credits, songs, and more about Jeff Lynne's ELO* – Alone In The Universe at Discogs. Complete your Jeff Lynne's ELO* collection. Given the breathtaking Given the avalanche of cornball arrangements of Christmas carols trilled by hundreds of pop singers cashing in on the holiday every year, this instrumental music is downright soothing. So, you’ve won, In honor of the 50th anniversary of ‘A Charlie Brown Christmas,’ we recount a few of the gifts the TV special has given to pop culture. Jayme Deerwester, USA TODAY A Charlie Brown. and animation te. Celebrate like the Peanuts gang when the Alex Murphy Jazz Trio performs the music of "A Charlie Brown Christmas" at 8 p.m. Dec. 16 at Vero Voce Theatre in St. Charles. "There’s a lot of iconic albums. Author adminPosted on March 14, 2019 March 14, 2019 Categories Music Lovers Previous Previous post: Play All Of Altar Of Praise Choir Old Hymns On Youtube Next Next post: Brandenburg Orchestra Concerto V Concerti Grossi
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CultureFood & DrinksNews & features Tom Sellers relocates restaurant to the Cornish coast this Summer for new residency Story by the Sea At the beginning of August, critically acclaimed chef Tom Sellers is set to close up shop at his award-winning, Michelin-starred London establishment Restaurant Story and take the entire team to the Cornish coast, where they will be launching a six-week residency in Carbis Bay titled Story by the Sea. This project will not only allow Story to bring the exceptional food they are known for to this stunning area of natural beauty, but over the course of the pop-up, they will work with creative ocean campaigners Parley to remove 50 metric tonnes of plastic from the oceans. Located at the Carbis Bay Estate, set on the privately-owned Blue Flag beach, visitors will be able to book for lunch or dinner seven days a week from August 2nd until September 14th and enjoy this ultimate gastronomic opportunity whilst lapping up views of golden sand beaches and blue seas. Diners will enjoy a unique five or six-course menu inspired by the ocean and created using all that Carbis Bay and the surrounding area have to offer. Dishes designed to celebrate the spectacular nature of the sea will include the likes of Crab Tart, Lobster & Leek and Lemon Sherbet. Known for its outstanding cuisine, masterful execution and playful creativity, Story by the Sea guarantees guests an unforgettable experience set in a breath-taking location. To drink, a cocktail menu has been carefully crafted to showcase the finest ingredients and will be served with innovative snacks at the bar. Twists on classic cocktails will feature in addition to some of the Restaurant Story signature drinks. The interiors will be a nod to Story’s London home, showcasing a contrast of traditional luxury with a contemporary aesthetic. An emphasis has been placed on natural textures and comfortable seating has been arranged throughout, whilst splashes of colour and warm lighting will illuminate the dining room. In addition to all this, and to further emphasise to the message of valuing the seas, Tom Sellers will be launching an exciting collaboration with Parley at the pop-up. Parley have teamed up with leading contemporary artists such as Doug Aitken, Jenny Holzer and Julian Schnabel to create a series of limited-edition upcycled tote bags, each made from five intercepted plastic bottles. The bags will be presented to guests at the end of their meal at Story by the Sea, resulting in 50 tonnes of marine plastic waste being removed from the oceans. The bags will also be available to purchase from the Story website for £15 with all proceeds going to help ocean cleanup. Every sale will lead to the removal of ten kilograms of marine plastic waste. Speaking of the motivation behind the project, Sellers said, “I have always had the fondest memories of the seaside and a very loving relationship with our oceans. The ocean is a magical gift we have been given, along with everything found within it, and I feel extremely lucky to have this opportunity to cook within Carbis Bay. The ocean and all that surrounds it will shape our vision for the menu’s creative process and cooking style.” Story by the Sea will run from 2nd August until 14th September 2019. The restaurant will be open seven days a week. The set menu will be available for £95pp for lunch for five courses and for £125pp dinner for six courses excluding service charge. To book a table at Story by the Sea, Carbis Bay Hotel & Estate St Ives Cornwall TR26 2NP, call 01736 795311 or visit their website here. More in Food & Drinks Murder Inc in Fitzrovia: A sleek hideout where grit and glamour meet Cristiana Ferrauti Roast in London Bridge: The Borough Market food institution Filippo L'Astorina, the Editor Launceston Place in Kensington: French inspiration, British produce and an emoji menu Ex-Fat Duck chef and sommelier Jonny Lake and Isa Bal’s new London restaurant Trivet to open in autumn Lucknow 49 in Mayfair: Tender, flavoursome curries slow-cooked to perfection Maria Barrios National Geographic Traveller Food Festival offers Londoners a world tour for their tastebuds on 20 and 21 July Xier and XR: The two faces of Carlo Scotto’s ambitious Marylebone restaurant Heads + Tales in West Hampstead: Easy and complex cocktails for the best of both worlds Eneko Basque Kitchen & Bar in Aldwych: A modern take on traditional Basque cuisine | Restaurant review
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Andargachew Tsege Foreign and Commonwealth Office written question – answered on 21st March 2018. All Written Answers on 21 Mar 2018 Alex Sobel Labour/Co-operative, Leeds North West To ask the Secretary of State for Foreign and Commonwealth Affairs, what recent representations he has made to his counterpart in the Government of Ethiopia on the imprisonment of British citizen Andy Tsege in that country. Hansard source (Citation: HC Deb, 21 March 2018, cW) Harriett Baldwin Minister of State (Department for International Development) (Jointly with the Foreign and Commonwealth Office), Minister of State (Foreign and Commonwealth Office) (Joint with the Department for International Development) The Foreign Secretary raised Mr Tsege's case with the Ethiopian Prime Minister and Foreign Minister at the African Union-EU Summit in November 2017, and subsequently raised Mr Tsege's case again with Foreign Minister Workneh in January this year. Our Ambassador also continues to raise Mr Tsege's case at the highest levels at every opportunity and Ministers continue to monitor the case very closely. Yes0 people think so No1 person thinks not (Citation: HC Deb, 21 March 2018, cW)
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Chipotle's Testing Craft Beer & Cocktails... and They're Actually Good By Lee Breslouer Published On 03/31/2016 @LeeBreslouer By Lee Breslouer @LeeBreslouer Published On 03/31/2016 Lee Breslouer/Thrillist The booze options available at a majority of the 2,000+ Chipotle locations in the USA are just like that ladies clothing store in the mall: limited. There are margaritas on the rocks and some beer. But that could be changing sometime in the near future, as a single Denver, CO location is rolling out a slew of boozy (and non-boozy!) drink options that may one day make your Chipotle visits a little more fun. We're talking about custom-made beers from legit craft brewers and cocktails that go beyond the marg. Why is this a big deal here? Historically, the company changes its menu as often as cicadas come out of hiding -- as in, seemingly once every 13-17 years. Over its 20+ years in business, the big changes were adding Patrón margaritas and the Sofritas protein. But not much else. Until now. According to Richard Betts, a master sommelier from Aspen's The Little Nell, he's been assisting on the new beverage program for two years. And based on what the good people of Denver think of the drinks (if you live in Mile High, it's the 6th Ave and Broadway location), they may or may not be coming soon to a location near you. Or they'll be dropped from the menu, never to be seen again. We tasted them all. Obviously. Here's the rundown. Chipotle's Next Move: A New Burger Chain? The margaritas available in most Chipotles are either Sauza- or Patrón-based, with triple sec, lemon/lime juices, agave, and ice. The company doesn't especially advertise the existence of said margs, but you can't miss the existence of its newfangled margarita, mostly because there's a huge frozen margarita machine next to the cash register. The new recipe swirling around inside that gleaming metal dream-machine has changed too: it's a 50/50 mix of Sombra mezcal and Astral tequila, lime juice, ice, and agave. The result is a margarita clearly superior to what's currently in the company's restaurants, though it's a bummer they don't salt the rims. Chipotle worked with the organic sangria-makers at Eppa to create a grenache and tempranillo grape-filled sangria that actually tastes like wine. Hooray for the drink not being a sugary mess! Betts is still tweaking the recipe, but for now there's a mix of pomegranate, blood orange, acai, blueberry, and citrus essences. And ideally it'll be available on tap, as it's more environmentally friendly than throwing out glass bottles whenever someone orders a sangria. Watermelon agua fresca This was by far the best new drink on the new menu. If it doesn't find its way to every Chipotle location, I'll be sad for the burrito-eating public. The ingredients are minimal: watermelon pulp, water, lime juice, and cane sugar. Drinking it feels like taking your taste buds to a water(melon) park and allowing them to frolic there for a bit. Now, if it only had booze in it... Agua de Jamaica and black tea Organically grown by In Pursuit of Tea, the agua de Jamaica tea is a blend of hibiscus flowers, rooibos tea, and lemongrass. You can just call it hibiscus tea if you don't feel confident pronouncing the phrase "agua de Jamaica." It's a traditional Mexican drink, and even though I only planned on taking a few sips, I kept going back for more. "One of the unique things about hibiscus is that it has its own acidity, its own structure," Betts said. "When you drink it, it makes your mouth water, it makes your belly rumble, it makes you want to drink more, and it makes you want to eat more." Perhaps this tea should come with a warning label that it's addictive. The black tea tasted unsweetened and was smooth enough, but the hibiscus was the real showstopper. Oskar Blues Brewery Mexican-style craft beer + actual Mexican beer Colorado's beloved Oskar Blues worked with Chipotle on the brand-new Vienna-style lager Beerito (basically, it's a Mexican lager brewed with German malts). And the brew's name is not misleading -- this can will go perfectly with your next burrito. It should be a crime to drink this without guac and chips nearby. OB will start shipping it in cans nationwide, so feel free to taste-test it yourself. The company also added $2 cans of Modelo. As Betts told us, "I can't walk by the register and not have one. It's impossible." This is also a good excuse to remember if your boss catches you drinking Modelo at lunch. Blue Sky fountain sodas Back when I was younger and had significantly less facial hair, I'd tag along on errands to my mom's favorite natural food store, and sometimes I'd grab a Blue Sky. The brand's been around since 1980. All Blue Sky sodas are sweetened with cane sugar, as opposed to high-fructose corn syrup, and contain no caffeine. Having them in Chipotle locations would potentially be the first time they're available as a fountain drink, with the flavors including lemonade, ginger ale, and orange-mango. The orange-mango soda feels like it could add a bright note to any meal involving hearty ingredients like pinto beans and barbacoa or carnitas. Lee Breslouer is a senior writer for Thrillist, and needs more agua fresca in his life. Follow him to tweets fresca: @LeeBreslouer.
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Court dismisses Ku Nan’s appeal to set aside order to surrender passport May 30, 2019 17:03 pm +08 PUTRAJAYA (May 30): Former Federal Territories Minister Datuk Seri Tengku Adnan Tengku Mansor, who is facing two charges or receiving bribes totalling RM3 million, has failed to set aside the order for him to surrender his passport to the court. This follows a unanimous decision by the three-man bench of the Court of Appeal today to dismiss Tengku Adnan’s appeal against the decision by Kuala Lumpur High Court judge, Mohd Nazlan Mohd Ghazali, on Jan 28, this year. Justice Datuk Umi Kalthum Abdul Majid, who lead the bench, said the panel was not persuaded that the High Court judge had wrongly exercised his discretion in rejecting Tengku Adnan’s application not to surrender his passport. “The (High Court) judge had considered all relevant factors in exercising his discretion judiciously,” she said while delivering the decision. The other judges on the bench were Datuk Harmindar Singh Dhaliwal and Datuk Lau Bee Lan. The Putrajaya Member of Parliament, who was present in court, was appealing against the High Court ruling to dismiss his application to set aside the order for him to surrender his passport to the court by increasing the bail amount. Justice Mohd Nazlan upheld the decision of the Kuala Lumpur Sessions Court (the case was later transferred to High Court) in imposing bail of RM500,000 on Tengku Adnan, 69, and for him to surrender his passport to the court pending the disposal of his case. In his application, Tengku Adnan also proposed for his bail to be increased from RM500,000 to RM1 million and that he was also prepared to report himself at the Malaysian Anti-Corruption Commission (MACC) office every month, if needed. Earlier, Tengku Adnan’s counsel Datuk Tan Hock Chuan submitted that High Court judge in his judgment inferred that his client was a flight risk. “The High Court judge is wrong, my client has no intention to flee as he wants to clear his name from the system. He has also obtained his passport temporarily twice and had returned it to the court. This shows that my client is not a flight risk,” he said. Deputy public prosecutor Julia Ibrahim replied that the surrender of the passport was an important condition so that the trial goes on without any delay. She said Tan was not able to show that High Court judge had wrongly exercised his discretion in delivering his judgment as the appellant could apply for his passport to be returned temporarily from time to time. “I also submitted that the documents showing the dates of his meetings in Indonesia and his daughter’s school registration in Australia had been given in advance. So, no reason for the accused not to make the application earlier,” she said. Last Nov 15, Tengku Adnan pleaded not guilty to a charge of receiving gratification of RM1 million for himself from a businessman, Tan Eng Boon, through a Public Bank cheque belonging to Pekan Nenas Industries Sdn Bhd that was deposited into a CIMB Bank account belonging to him (Tengku Adnan) to obtain approval for an application by Nucleus Properties Sdn Bhd (now known as Paragon City Development Sdn Bhd) to raise the plot ratio of the site with development at Lot 228, Jalan Semarak, Kuala Lumpur, on Dec 27, 2013. He also faces an alternative charge where, in his capacity as the then Minister of Federal Territories, he is alleged to have received for himself RM1 million without consideration from Tan through a Public Bank cheque belonging to Pekan Nenas Industries Sdn Bhd which was deposited into his account, despite knowing that Tan, who is a director at Nucleus Properties Sdn Bhd (now known as Paragon City Development Sdn Bhd), was concerned with his official function. On Dec 12, he was also charged as a public servant in his capacity as the then Federal Territories Minister with receiving valuables, without consideration, amounting to RM2 million from one Chai Kin Kong, through a Hong Leong Islamic Bank cheque belonging to Aset Kayamas Sdn Bhd, which was deposited into a CIMB account belonging to Tadmansori Holding Sdn Bhd in which he (Tengku Adnan) had an interest and which he knew had connection with his official function, on June 14, 2016.
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Tactical toilet breaks and apple on willow: what free-to-air cricket could inspire Max Rushden Putting the Cricket World Cup final on free-to-air TV could just be a one-off, but what if it was the start of something more? @maxrushden Hambledon Cricket Club second XI take on Mansbridge at the Ridge Meadow ground. Photograph: Tom Jenkins/The Guardian In the summer of ’93, everyone at my school became a leg-spinner. We’d never seen leg-spin before Shane Warne arrived. Not that we could remember. No one could do it – ball after ball just looping on to the top of the low‑hanging cricket net – batsmen waddling halfway down the green matting, jumping and trying to hit the ball back to the bowler, hopefully with enough power to do it in one go. We were hopeless, but we were inspired by what we saw on TV. Fear and loathing in cricket's fraying heartland | Andy Bull Sky’s agreement to put the Cricket World Cup final on free-to-air television could just be a one-off, but what if it was the start of something more? It wouldn’t have been hard to put the game on regardless of the result of England’s semi-final but perhaps the England and Wales Cricket Board has worked out that not enough of us are watching it. Living in a Sky Sports bubble (and being in it for years) makes it difficult to conceive of a world without live sport at my fingertips. Pretty much every office I sit in pumps out every possible sport on every possible TV. Sky Sports Football, Sky Sports Cricket, Sky Sports News, Sky Sports Kabaddi, BT Lorry Racing. It’s all on, all the time. I genuinely forget that others don’t have that luxury, and haven’t had the chance to watch cricket for the past 14 years – during which time the coverage has been consistently excellent. All those summer days watching Bumble and the others teasing Nasser Hussain about the size of his nose, seeing which pundit has been given the third man analysis role against their will. The evenings spent watching Charles Colville and Bob Willis getting increasingly annoyed – perhaps because they have been left to do the highlights. And that’s before the winter – getting up at weird hours to watch overseas tours wondering if Tim Abraham has enough sun cream, or getting ready to start your day, flicking on the Big Bash and then realising it’s midday and you’re not dressed. Cricket World Cup final to be shown on free-to-air TV As revealed in the Guardian, the Cricket World Cup final will be shown on free-to-air television now that England have qualified for the showpiece event against New Zealand. "Eoin Morgan has backed the decision to show the Cricket World Cup final on free-to-air television, a story revealed in the Guardian. "It's very cool," said England captain Eoin Morgan. "Particularly given the 2005 Ashes for me was the day cricket became cool – it was front and back page, everyone talking about it – that’s really good for the game. It’s great news it’s on free to air." The match will be screened from 9am on both Channel 4 and Sky Sports, which holds the UK broadcast rights. However, Channel 4 are also due to show the British Grand Prix on Sunday – the only live free-to-air slot for Formula One on British television this season – meaning cricket coverage will switch to More 4 for the duration of the race at Silverstone. The number of people who will understand those references is actually pretty low. As Sean Ingle pointed out in 2015, almost as many people watched a 1974 feature-length episode of Columbo on ITV3 as watched Joe Root take the winning catch at long-off at Cardiff in the first Ashes Test of that year. And while Ingle clearly fails to recognise Peter Falk’s televisual brilliance, it’s a worry. Eight and a half million people watched the culmination of the fourth Test in 2005. I don’t walk down the street with English cricketers enough to know whether they get stopped every five seconds or whether they’re anonymous when they’re out shopping. Do 20-year-olds have equivalents of Peter Such and Alan Mullally rattling around their brains taking up much needed space? Will the modern day cricketers break into our public consciousness? Will Mark Wood win Strictly? Will Keaton Jennings present Top Gear in 2035? Participation is down. Andy Bull recently noted that 40 sides had disbanded in the past five years in the Hampshire league, with many others losing their second, third and fourth XIs – added to this is the slow acknowledgement that the sport is becoming the preserve of the privileged to an increasing degree. ‘Village cricket. What a thing that is. Teammates decades apart in age and feet apart in waistlines, with one large man lodged at first slip in every side’ Photograph: Alamy And what a shame. Because there is something so weirdly, but fantastically, different about playing cricket, compared to any other team sport. A whole day of playing sport, where you might win it single-handedly, and on another day you might do literally nothing. Not a thing. It’s sad to think fewer and fewer people will create their own cricketing memories – those batting gloves at school with the green rubber spikes which gave you no protection whatsoever, and pads with buckles that pointedly refused to stay in place when you ran a quick single as your box fell out of your pants and wedged itself behind your knee. At university, second XI cricket was not of a high standard. Dan was the only player who could bowl straight. He’d always begin with an orange, aiming for off stump and we would wait for the glorious sound of citrus on willow. After we’d clear up the vitamin C explosion, we’d apologise and get on with the game. Then came the twist – the wicketkeeper would take a Red Delicious out of his pocket – we’d throw it around the field, from slip to point to cover to mid-off, shining it on its way round – and Dan would bowl that. Follow Guardian sport on social media Twitter: follow us at @guardian_sport Facebook: like our football and sport pages Instagram: our favourite photos, films and stories YouTube: subscribe to our football and sport channels Photograph: Chesnot/Getty Images Europe Apple on willow, shattering all over the square. On one occasion, their opener played the first ball/apple perfectly – a cultured leave outside off stump. The keeper took it with soft hands and we threw it around the field again, desperately trying to keep a straight face, before the apple hit the middle of the bat on the second delivery. I’m not sure I’ve even been so happy. It was stupid, and we were idiots, but we were idiots playing sport. Probably the most exhilarating single moment of my life (admittedly the bar is low) came while playing village cricket. What a thing that is. Teammates decades apart in age and feet apart in waistlines, with one large man lodged at first slip in every side. The tactical toilet break so that you don’t have to umpire the first 10 overs – and if you end up in the middle the complete refusal to give any lbws. There was one game a year when the fair came to town and took up half the village green – I’d be crouching at gully while Chic’s Le Freak blared across the field. In the 2003 Cambridgeshire Junior cup semi-final, requiring five off two for Ashwell, I hoyed one over cow corner for six – it even got a headline in the Royston Crow. That very rare feeling of striking a ball so sweetly that it didn’t feel like I hit it. We won the final – I did not bowl, did not bat. Did not do anything. I still have the trophy in my toilet. Here’s hoping Sky’s free-to-air offerings don’t stop after this tournament. What about a day of an Ashes Test this summer? A Premier League game this season? If we want more people to watch, play and be inspired, it has to be the right thing. The Spin: sign up and get our weekly cricket email. Television industry Sky plc
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Congressman's murder in Kannur: Two CPI (M) workers arrested, BJP seeks CBI probe However, the opposition Congress said the two accused were not the real culprits. Monday, February 19, 2018 - 07:27 Two CPI (M) workers have been taken into custody for the brutal murder of a Youth Congress worker near Kannur around a week ago, police said on Sunday. Accused Akash and Rijin Raj are also allegedly involved in another murder. However, the opposition Congress said the two accused were not the real culprits while the Bharatiya Janata Party demanded a CBI probe. Congress worker Shuhaib, 30, was waiting at an eatery near Mattanoor around 10.45 p.m on Monday when four persons riding a car hurled bombs to create panic and then fatally slashed him with a sword. A picture of both allegedly posing along Chief Minister Pinarayi Vijayan and Communist Party of India-Marxist State Secretary Kodiyeri Balakrishnan has now come out. "To the best of our knowledge, the two CPI-M workers in custody are not the real culprits. What is even more intriguing is that police did not arrest them. Instead, local CPI-M leaders presented the two accused at the police station. All this while the CPI-M leadership was saying that the party had no role in the murder but it has now been proved wrong," senior Congress leader K Sudhakaran said. Kodiyeri Balakrishnan, however, downplayed the issue and said the ruling party will take action if any party member was involved. "Let police do their job and decide who are the culprits," said Balakrishnan. State BJP President Kummanem Rajasekheran told the media that the two accused were housed at the state CPI (M) headquarters in Kannur. "For long, state CPI (M) first denies role in such murders but later it comes to light that the accused are CPI (M) workers. What is suspicious now is that the two were presented to police by local CPI (M) leaders. For the truth to come out, only a CBI probe will suffice," said Rajasekheran.
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Home Andalucia Sevilla Digital age of Spanish art Digital age of Spanish art 3 May, 2011 @ 17:33 A FESTIVAL of digital culture is to kick off in Sevilla this month. The first Ubicua festival aims to blend cutting-edge art with new technologies. It will coincide with the opening of the new Laboratory of Art and Digital Culture at the University of Sevilla. World-renowned media artist Daniel Canogar will present his work at the festival, which also features hands-on workshops and a discussion on the evolution of the digital age. A panel of judges will select three future project proposals to receive funding and each day will end with a digital video installation and performance. The festival runs from May 18-20 at the former Labour Law building on Calle Madre de Dios. About Wendy Williams DO YOU HAVE NEWS FOR US at Spain’s most popular English newspaper - the Olive Press? Contact us now via email: [email protected] or call 951 273 575 Thousands evacuated as forest fire spreads along Costa del Sol - 31 Aug, 2012 @ 11:01 Irishman shot in Torremolinos bar - 28 Aug, 2012 @ 10:27 Experts confirm remains found on Cordoba estate belong to missing youngsters Ruth and Jose Breton - 27 Aug, 2012 @ 17:02 Naked Chef Jamie Oliver in Marbella - 24 Aug, 2012 @ 18:24 ‘Sickening’ kitten attacks in Estepona - 22 Aug, 2012 @ 12:55 Little and large: Petite star Eva Longoria poses with fellow diner in Marbella - 21 Aug, 2012 @ 13:23 Sheikh to sell Malaga FC - 19 Aug, 2012 @ 13:00 Mercadona recalls cosmetic products linked to cancer - 15 Aug, 2012 @ 13:57 David Cameron enjoys a summer holiday in Spain - 15 Aug, 2012 @ 10:28 Gibraltar’s biggest ever dance festival set to attract some of the best DJs to the Rock - 27 Jul, 2012 @ 11:46 Previous articleOne in five children suffer sexual abuse in Spain Next articleAll aboard the Ark Royal in Gibraltar Spain’s Government SEIZES former dictator General Franco’s €5 million summer palace over its ‘fraudulent’ sale Brit, 20, robbed of €400 by ‘hugger muggers’ in Benidorm on day one of first-ever lads’ holiday
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Summer is on its way - Scarborough set for a glorious weekend Scarborough in the sunshine Dig out your barbecues and picnic blankets, summer is heading to the Yorkshire Coast this weekend. The start of the week saw weather warnings over thunderstorms and torrential rain, but the next few days are set to see plenty of warm sunshine - with some parts of the country seeing the hottest temperatures of the year so far. The Met Office says that although a breeze off the North Sea will keep Scarborough cooler than other areas of the UK, Temperatures will peak on Saturday, reaching around 23C in the afternoon, and it will remain humid overnight, only getting down to 15C for sleeping. Sunday looks equally glorious, with blue skies and sunshine, although temperatures may be a few degrees lower than on Saturday. Met Office Chief Meteorologist, Steve Willington, said: “It’s going to get very warm across parts of the west and southwest of the country from Wednesday, and it’ll feel hot in places across southern and western parts of the UK by Friday, with temperatures possibly reaching 30C in a few spots. Not everywhere will see the high temperatures, however, as an easterly breeze will keep North Sea coasts much cooler. “By Saturday the warmth will spread further east with temperatures into the low 30s Celsius in places, while further west much fresher, but still warm conditions are expected. Fresher conditions will then spread to all parts of the UK by late Sunday.” THREE weather warnings for the Yorkshire coast - this is when and why Scarborough Race for Life 2019: are you in these pictures? Scarborough businessman who drove through a road closure threatening two workmen and calling them names is spared jail 'If you cause trouble, you will get banned' - Scarborough pub landlords send powerful message to stop violent behaviour Here's the decision on Matalan's bid for a cafe in its Scarborough store
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Opera, Broome style6 days, 23 hours ago Opera Under the Stars set for Broome, with Teddy Tahu Rhodes top of bill DEVILISHLY GOOD: Teddy Tahu Rhodes as Mephistopheles in Faust. One night only event to be held in lush gardens of Mangrove Hotel. Leave the dickey suits and twin sets behind and enjoy opera tropical style at Opera Under the Stars in Broome on August 31. Against the backdrop of Roebuck Bay, internationally acclaimed bass-baritone Teddy Tahu Rhodes will be joined by young singers Georgia Wilkinson (soprano) and Bronwyn Douglass (mezzo-soprano), with Phoebe Briggs on piano. The one night only event will be held in the lush, gardens of Mangrove Hotel, with tickets on sale now. Tahu Rhodes has performed with the opera companies of San Francisco, Austin, Washington, Philadelphia, Dallas, Cincinnati, Houston, New York, Hamburg, Munich, Paris, Vienna, Wales and Scotland. In 2019 he will perform Titurel in Parsifal(Victorian Opera). For Opera Australia, he will be Lord Sidney in Il viaggio a Reims, Enrico VIII in Anna Bolena and Mephistopheles in Faust. He will also feature in the all-star Australian tour From Broadway to La Scala. Audience members have the choice of premium seating (reserved area) or general seating (unreserved area). And for the first time, a limited number of deck bayside tables and verandah upstairs tables will be available. For details, bookings and pre-opera dining options, visit operaunderthestars.com.au. WHILE YOU'RE THERE If you're still in the mood for entertaiment al fresco, check out Broome's historic Sun Picture Theatre, where moviegoers lounge in deck chairs under the night sky. Since screening its first film in 1916, the cinema has survived tidal floods, World War II, cyclones and the advent of television and video entertainment. Facing the town of Broome, Roebuck Bay is a great spot to grab your binoculars and watch the millions of migratory birds that visit its shores each year. Also see Broome Bird Observatory, shorebird capital of Australia and one of the world's great bird-watching destinations. Join a tour or take part in the nightly Bird Log,sharing your observations and hearing what other birds and animals have been seen around the area. For another view of Broome, join one of the town's camel tour operators for a ride along Cable Beach. Or get behind the wheel and see the outback, heading north from Broome. The Gibb River Road is one of the last true bush experiences, passing vast cattle stations, remote wildlife sanctuaries and stunning gorges. Highlights include El Questro wilderness park and homestead, boab trees, bush hospitality, working stations, Argyle diamonds and Derby's 11-metre tides. READ MORE: See opera under the stars at Uluru READ MORE: Anne Boleyn, Brett Whiteley get digital treatment in OA's 2019 winter season
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You Can Take a Disney Cruise With Your Favorite Marvel Characters Next Year “The largest collection of Marvel superheroes and villains ever assembled on a cruise ship.” By Talia Avakian Holger Leue/Getty Images Marvel fans will get a chance to cruise with their favorite superheroes next year, aboard each of the seven Disney Magic sailings, set to depart from New York City starting next fall. The day-long celebration aboard the cruises, called Marvel Day at Sea, will feature photo sessions with Marvel characters like Spider Man, Thor, and Captain America, Marvel-themed trivia competitions, games, and arts and crafts sessions, and exclusive film screenings. Courtesy of PRNewsFoto/Disney Cruise Line Guests will get a chance to check out the latest Marvel releases and Disney XD shows like “Marvel’s Avengers Assemble,” “Marvel’s Ultimate Spider-Man,” and “Marvel’s Guardians of the Galaxy.” Plus, fans will get to kick back with their favorites at a deck party, which Disney Cruise Line claims will have “the largest collection of Marvel superheroes and villains ever assembled on a cruise ship.” The new Marvel Day at Sea will take place on the seven- and eight-night Disney Magic Bahamian cruises, which leave from New York on October 6, 14, and 28, and on November 4, 11, and 18 of next year, and include a day at the Walt Disney World Resort. The Marvel-packed adventure will also be available on one of the seven-night Canadian coast cruises, which will be leaving from New York on October 21 and make stops in Charlottetown, Sydney, and Halifax. Popular in Cruises Everything You Need to Know About Disney Cruise Ships What It's Like to Cruise Down the Danube River Why Adults Prefer Disney Cruises, Even If They Don't Have Kids The Caribbean Island That Disney Fans Can't Get Enough Of Disney Cruise Line Just Announced 2020 Sailings — Here's How to Book Your Dream Cruise You Can Take a 'Beauty and the Beast'-themed River Cruise Through Europe Disney Cruise Line Secrets No One Tells You Why a Disney Sailing Is the Best First Cruise for Young Kids Disney Announces Their 2017 Cruise Itineraries With New Ports of Call Disney Cruise Line Is About to Bring More Magic to the Sea With 3 Massive New Ships All Topics in Cruises
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Last updated: 03:22 PM ET, Thu April 28 2016 Celebrate National Superhero Day With Batman and Superman’s First Cruise Entertainment Gabe Zaldivar April 28, 2016 Image via Flickr Batman and Superman have battled the most nefarious villains in the DC universe. They have gone to war with one another. And, most importantly, they shared a tiny cabin aboard a cruise ship on holiday the first time they met. Thursday is National Superhero Day, which means it’s perfectly fine to play hooky from work and read your comic books all day. (We highly recommend not divulging the entire story to said employer, however). This also marks an especially wonderful moment for the travel industry. Because, as you all know, Batman first appeared with Superman way back in 1952 in Superman Vol. 1 #76 when the pair met on a cruise ship. The comic’s titled “The Mightiest Team In the World,” which is only slightly dumber than “Dawn of Justice.” DC Comics’ Wiki page walks us through this remarkable superhero yarn that features two alter egos finding out that by happenstance they would have to share a room aboard a cruise ship. [Cue the Debbie Downer noise] Image via DC Wikia Let’s see if we can sum up quickly. Batman has just cleaned up Gotham completely. And with nary a criminal on the loose, he decides to take a cruise. Coincidentally, Superman decides he is in need of some relaxation so he books a trip on the same cruise, the good ship Varania. Before we continue, we should say that Batman and Superman don’t take cruises. Families take cruises. Retirees take cruises. Bachelorette parties take cruises. People with an unhealthy predilection for buffet menus take cruises. Superheros that have the ability to fly – either by Batwing or the power of the sun – travel the globe solo. READ MORE: 9 Places To Enjoy Batman V Superman Around The World In any case, it seems Varania was overbooked or something, because Clark Kent and Bruce Wayne, a man who can afford several ships, are forced to room together. Before the ship leaves, some doofus explodes a fuel truck, which is his elaborate way to get away with stolen diamonds. Kent and Wayne change into Superman and Batman, respectively. It’s at this moment the two realize they are actually more than just a middling reporter and the world’s richest man. We kind of wish the scene played out with befuddled looks and ten minutes of, “But…I’m…That means you’re…But then…So that means…” The rest unfolds kind of like it would if Warner Bros. had booked Adam Sandler to replace Zack Snyder (which may have worked out better in the end). The dastardly fiend, John Smilter, makes his way onto the Varania with the diamonds and the dynamic duo are forced to head onboard to foil his escape plan. While the two sleuth their way to unveil the suspect they are forced to pull a fast one on Lois Lane so as to preserve their most treasured identities. This includes Kent feigning sickness, Superman taking Batman to Gotham for a quick crime thwarting and Wayne disguising himself as Kent. All in all, it’s a great read and marks the first time, in Earth One, that the Bats and Supes play nicely together. But, then again, you shouldn’t actually pop this open if you own it. According to Comic Book Realm, the thing goes for $4,000, so keep that baby in its plastic cover. Now remember, the greatest story that DC Comics ever told happened somewhere else. But, thankfully, the 76th issue of Superman took place on a cruise ship. Treasure that little nugget as you eat Doritos and watch superhero movies on this most magnificent of days. Follow @gabezal For more Entertainment News More by Gabe Zaldivar gallery icon 15 Of The Most Insane Pizzas In America And Beyond gallery icon Filming Locations for Top 2019 Oscar Nominated Movies Disney Announces Opening Date for Skyliner Gondolas gallery icon Extreme Roller Coasters Across America SeaWorld and Busch Gardens Offer Half-Off Admission for First Responders What's New This Summer at Disneyland and Walt Disney World An Island Getaway in Mexico AMResorts Blog
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Well, it’s that time again… Here in HK the weather is hot, sticky and often wet… all at the same time. Thanks goodness for air conditioning! This past month though has also been busy up in China… we’ve been visiting a couple of new factories which I’m hopeful can help alleviate at least some of our production headaches. At the same time there’s also lots of figures and models we’re preparing for upcoming releases in the next few months that have to be checked and evaluated… All in all, plenty to keep us busy. So without further ado… 1. WHAT’S ARRIVING IN AUGUST… A. “Napoleon in Egypt… Part Deux (2)” Five all-new pieces… four figures and a display item… NE004 “Soldier Pointing” Another of Bonaparte’s men pointing out the ancient wonders of the Land of the Nile. NE005 “Soldier with Sun Canopy” This infantryman has rigged up an ingenious way to shade himself from the blazing desert sun… NE007 “Chef de Musique” This colourful Napoleonic musician has definitely “gone native”… In addition to his baggy Mameluke-style pantaloons he has also equipped himself with a Mameluke sabre. NE009 “The Monument” Soldiers the world over, have, for centuries sought to leave their mark… On these ancient stones one of Bonaparte’s men has already carved the General’s name. NE014 “The Graffiti Artist” One more French infantryman cannot resist the impulse to leave his name on the “Ancient World” Note: Look out for more “Napoleon in Egypt” releases later in the year! B. “Egypt Again… but a little earlier” Many centuries before Napoleon Bonaparte invaded Egypt another, much prettier, ruler made her name there… Cleopatra! AE039 “Cleopatra and Her Handmaidens” Egypt’s fabled Queen enhances her natural attractions with a little cosmetic assistance. Three figure set. AE040 “Court Official” While the Queen beautifies herself one of her high court officials makes a report… From the goings-on at court we move to a more humble duty… AE043 “The Water Carrier” A classic pose for an everyday occurrence and… a useful figure in any Middle Eastern scenario. AVAILABLE: Mid-August C. “SCOTS WHA HAE!” In Scotland in 1314, the nation was still under English rule… the times however were changing and the Scots were about to challenge the might of the English Crown… During my schooldays (many moons ago) every Scottish school boy knew the story of the Battle of Bannockburn when King Robert the Bruce won Scotland’s freedom from England and the rule of Edward II. One of the most famous events of the battle actually happened the day before… Robert the Bruce was in front of his small Scottish Army when an English Knight… Sir Henry de Bohun detached himself from the much larger English Army and charged his heavy war horse across the heath that separated both forces and headed straight for The Bruce. De Bohun, lowered his lance and prepared to “spear” the lightly armed Bruce from his saddle… At the last minute Bruce neatly sidestepped his own mount and brought down his battle axe on de Bohun’s helmet, cleaving it and its owner’s head in two! A great cheer went up from the Scots… a loud collective groan from the English… One nil for Scotland and a terrific omen for the battle the following day… MK083(SL) “THE DUEL” (Robert the Bruce and Henry de Bohun) This great two-piece vignette captures the moment when the Scottish King is about to bring his battle axe down on de Bohun’s head! A “Strictly Limited” Edition of 750 sets D. “THE TYPHOON TANKBUSTER” Moving on from a time when English and Scots were fighting each other to a time when together they were fighting a much more dangerous and deadly foe… RAF030 “The HAWKER TYPHOON MK.1B” Widely recognized as the best and toughest ground /attack fighter bomber of WW2 the HAWKER TYPHOON is K&C’s most detailed warbird yet! Our version of this powerful aircraft carries 8 underwing, anti- tank rockets and has 4 hard- hitting Hispano cannon. A seated pilot is in the cockpit of this Typhoon from 257 squadron, Royal Air Force. It also bears the bold black and white “invasion stripes” of all Allied aircraft flying over the Normandy landing beaches on and after June 6, 1944. NOTE: Just 500 are being manufactured. Supporting this Typhoon are a selection of RAF ground crew… RAF031 “Rocket Primers” Two RAF Aircraftsmen assemble one of the tank-busting rockets. RAF032 “Rocket Handler” A single RAF ground crew member “shoulders” one of the rockets to the aircraft. RAF033 “Sitting Airman” Many wartime photos show airmen “perched” on the wing of an aircraft… including Typhoons. RAF034 “Airman Radio Operator” Equipped with a back pack radio this airman is in touch with other RAF ground / air units in the area. RAF035 “Typhoon Pilot” Enjoying a welcome “smoke” and a cup of “Char” this pilot is taking a welcome breather between ops! RAF036 “Flight Sergeant” A “new” version of an old favourite… from our Battle of Britain set of RAF Ground Crew dating back almost 20 years! UNIFORM NOTE: By mid-war many RAF pilots and ground crew could be seen wearing British Army battledress (with relevant RAF rank badges) while on active duty. As these releases go with our new Hawker Typhoon as it might be seen in forward battle airfields in Normandy after the invasion it is appropriate that some of them are in army Khaki as well as RAF blue. AVAILABLE: Late August E. “RETURN TO AFRIKA” AK078 “AK Officer with Schmeisser” Wearing his AK greatcoat to fend off the desert chill this officer is about to fire a burst from his machine pistol… AK079 “AK Rifle Section” Two more greatcoat-clad infantrymen with rifles. AK080 “AK Grenadier” AK081 “AK Machine Gunner” Difficult but not impossible… this gunner fires his magazine- fed MG34 from the hip. AK082 “AK Observation Team” This two-man set of officer and NCO… One observes the enemy position… the other uses the field telephone to call in an artillery or mortar strike. AK083 “British Prisoner” For this dejected Tommy a POW cage looms up! AK084 “Panzerjager 1” Based on a Panzer 1 tank chassis this self-propelled gun mounts a 4.7 cm Czech-made Skoda gun and was the first German tank destroyer of WW2. Our model comes with a standing crewman. SPECIAL NOTE: A field-grey version will be in September 2. COMING IN SEPTEMBER A. AK077 “AK Captured Morris CS8 15cwt. Truck” (Series 250) As virtually everyone knows the German Army made much use of “captured” enemy vehicles throughout the war… Rommel’s Afrika Korps were no exception! Here, complete with driver, is one of the “liberated” vehicles, the classic British Morris 15cwt. Truck still in its 8th Army colour scheme but with prominently displayed German crosses on the sides and on top of the engine. Special Note: This little 15cwt truck is a “Series 250” release, three other versions will be available… i) RAF (blue) with WRAF driver. ii) 8th Army (desert splinter camo) with Aussie Driver iii) British Army (black /Olive drab Mickey Mouse camo) with British Army driver. AVAILABLE: Early September B. “A FLIGHT OF EAGLES” From the desert sands of North Africa to the gray skies over northern France and Belgium during the First World War. Finally, our little biplanes line up on the airfield … and come with famous pilots too… and in three different versions! FW098(S) “Albatros DV (Von Richtofen)” Although Manfred Von Richtofen is usually pictured in his famous all red-Fokker Tri-plane he originally achieved fame flying an all-red Albatros… and that’s how he and his aircraft are pictured here. FW099(S) “Albatros DV (Goering)” This particular Albatros was flown by the future Luftwaffe Chief before he took over command of the “Flying Circus” after the death of the Red Baron. FW105(S) “Albatros DV (Voss)” German flying ace Werner Voss flew one of the most colourful and brightly marked Albatros of any of the leading pilots. The swastika on the fuselage was originally intended as a good luck symbol… In addition to the “pilot ‘n’ plane package” all three German Air Aces are also available as single figures… FW106 “Lt. Werner Voss” FW107 “Manfred Von Richtofen” FW108 “Hermann Goering” C. “BERLIN ‘38” From the skies above France and Belgium during the Great War we move forward 20 years to the streets of pre war Berlin… LAH139 “Marching Flagbearer” A new-updated version of a now retired figure…. Carrying the “blood” banner. LAH140 “Marching SS Banner-man” LAH142 “Standing with Banner” This particular SS officer is wearing the dress “aiguillettes and gauntlets” of the 1st company of the “SS Leibstandarte Adolf Hitler”. LAH143 “Standing-At-Ease SS Officer” LAH144 “Father & Son” An SS officer and his Hitlerjugend son. LAH145 “Reichsfuhrer SS Himmler” In 1938, with the war clouds gathering, Himmler decided that he and his men should also have field gray uniforms just like the German Armyas well as their traditional black garb. LAH146 “At-Ease “Sepp” Dietrich” LAH149 “Panzerjager 1” When the Leibstandarte was incorporated into the Waffen SS this was one of the first armoured vehicles they were equipped with. The set includes the vehicle commander. LAH150 “Double Banner Street Lamps” For any parade or Berlin Street scene the new Street Lamps make a useful addition… swastika banners on one side… SS rune banners on the reverse. AVAILABLE: Mid-September D. “Luftwaffe Conference” LW048 “A Squadron of Spitfires!” At the height of the Battle of Britain in 1940 Chief of the Luftwaffe, Hermann Goering was becoming increasingly impatient with his air force’s inability to decisively crush the Royal Air Force. At the same time the Luftwaffe was beginning to lose an growing number of aircraft to the British. He decided to pay a visit to his frontline squadrons in France to find out for himself what was going wrong… Traveling on his private train the Reichsmarshall summoned Adolf Galland and Werner Molders, two of his top fighter aces, to meet him and discuss the worsening situation. At first he berated the two leading pilots and accused them (and their fighter units) of not doing enough to protect his bombers. After a while, his mood softened and he asked them both how to succeed…and what they required? Galland looked at Molders… Molders look to Galland… and finally Galland said, “A squadron of Spitfires!” The Reichsmarshall was not amused. This little vignette set portrays the historic meeting… E. “ON THE OTHER SIDE OF THE CHANNEL” Four years later, the shoe is on the other foot… now, it’s the Germans who are on the defensive as the British, Americans and Canadians prepare to launch a mighty invasion to free occupied Europe from the Nazi Jackboot. DD154(SL) “The Eisenhower Staff Car Set” This latest “Strictly Limited” shows supreme Allied Commander General Dwight D. Eisenhower on a tour of inspection somewhere in southern England in the spring of 1944. His U.S. Army Staff Car comes complete with a female WAC driver. At Eisenhower’s side is Kay Summersby, his personal driver when he arrived in Britain in1942. Over the next three years she proved invaluable to him and took care of many of his domestic and personal tasks. During this time Summersby became a U.S. citizen and was commissioned into the U.S. Women’s Army Corps (WAC’s) leaving the service as a Captain in 1947. Please Note: Just 750 of this special set have been produced. DD155 “Saluting British Military Policeman” DD156 “Escort Officer” Wearing the famous “IKE” jacket this U.S. Army Officer is a perfect “add-on” to accompany any senior inspecting officer. DD157 “Escort MP” Where the “brass” go the MP’s are sure to follow… DD158 “Gen. Omar Bradley” Omar Bradley the “soldier’s general” inspecting the troops… DD159 “US Soldier Port Arms” A GI in his parade uniform being inspected. AVAILABLE: Late September F. CHARACTERS FROM THE “THREE KINGDOMS”… Two striking figures from Chinese History IC036 “Zhou Yu” Plays an important role in defeating the enemy troops in the “Battle of Cliffs”. He’s also considered handsome, loyal and multi-talented, a poet and a musician. IC037 “Zhuge Liang” A well-known military strategist and statesman in the “Three Kingdoms” period. Our figure shows him in a typical pose holding a hand fan. 3. “HEADING FOR THE HILLS…” Here’s the latest retirements list… CW014 “Marching Officer” CW015 “Wounded Flagbearer” CW016 “Marching Rifleman w/Pipe in Mouth” CW018 “Rifleman Marching” CW019 “Kneeling Firing Rifleman” CW021 “Standing Firing Rifleman” CW022 “Standing Ready” CW023 “Standing Loading Rifle” CW024 “Kneeling Loading Rifle” CW025 “Advancing Confederate” The Age of Napoleon NA170 “Mounted Officer” NA171 “Marching Drummer” NA172 “Marching Officer w/ Sword” NA173 “Marching w/ Rifle” NA174 “Marching Set” NA175 “Marching w/ Flag” NA176 “Advancing Forward” NA177 “Shouting Corporal” NA178 “Standing Firing” NA179 “Standing Ready” And so friends, that’s the story so far… I hope you find something that interest you…and your collectors. Many thanks again for your continued support and advice. All the best and… adios for now! Co-Founder & Creative Director
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Alabama schedule issue remains unresolved By Chase GoodbreadSports Writer The Southeastern Conference's efforts to reduce the number of football opponents that will be idle before playing the University of Alabama this fall are continuing, but the issue remains unresolved. BIRMINGHAM | The Southeastern Conference's efforts to reduce the number of football opponents that will be idle before playing the University of Alabama this fall are continuing, but the issue remains unresolved. Six of Alabama's eight SEC opponents are scheduled to be idle prior to facing the Crimson Tide, a number the conference has been working to reduce since December. Commissioner Mike Slive indicated Monday that the challenge has been a difficult one. “(Associate Commissioner) Mark (Womack) has taken the lead with that and we talked about it the other day. We're not through yet,” Slive said. “We'll do whatever we can. We knew it wasn't going to be easy, but we're working on doing what we can.” The SEC has looked into moving both conference and non-conference games in order to reduce the number, and has previously indicated hope for a resolution by the end of this month. According to SEC Associate Commissioner Charles Bloom, the league is seeking willing partners in altering the schedule and has no plans to impose a schedule change against the will of a member institution. Athletic directors at two SEC schools - Arkansas and Auburn - have indicated they have no interest in altering their conference schedules. Auburn is idle prior to playing UA. Arkansas is not idle prior to facing UA, but is involved in a game against South Carolina that, if moved, could have reduced Alabama's number of idle-rested opponents. Other teams idle prior to facing UA this fall are Tennessee, Ole Miss, Mississippi State and LSU. Resolving the issue without affecting the SEC schedule would require at least one of those six schools to move a non-conference game into the idle date preceding Alabama on its schedule. Even that, however, could prove difficult. As an example, LSU's four non-conference opponents - West Virginia, North Carolina, McNeese State and Louisiana Monroe - are all playing other games on Oct. 30, which is the Tigers' idle date before facing UA. Slive declined comment on whether the league is now considering only non-conference options. League athletic directors unanimously agreed in December to add a long-term scheduling parameter to maintain more balance in the scheduling of idle-rested opponents. With 2010 football schedules already set, however, fixing the problem in the short-term is more difficult. Reach Chase Goodbread at chase.goodbread@tuscaloosanews.com, or at 205-722-0196.
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MediaTek Selects Dolby Vision for 4K UHD TV Available on HDR TVs, UHD Blu-ray players and digital media adapters Michael Balderston SAN FRANCISCO and HSINCHU, TAIWAN—MediaTek has announced that it will go with Dolby Laboratories’ Dolby Vision 4K UHD system-on-a-chip technology for its high-dynamic range TVs, Ultra HD Blu-ray players, and digital media adapters. Dolby Vision offers increased UHD and HD video signals for OTT online streaming, video on demand, broadcast, UHD Blu-Ray, and gaming applications. Dolby Vision’s VS10 universal HDR playback technology supports dual-layer and single-layer Dolby Vision streams and other HDR formats based on the SMPTE ST 2084 standard. This allows for peak brightness, local contrast and wider color gamut. MediaTek is a developer of systems-on-chip technology for mobile devices, wireless networking, HDTV, DVD and Blu-ray. The company is headquartered in Taiwan. Dolby Laboratories is a provider of audio, video and voice technology based out of San Francisco. 4KMediaTekDolby VisionnewsUHD TVDolby Dolby Labs, MStar Team on 4K UHD TV SoCs Dolby Vision HDR Added to Universal Titles A slate of films from Universal Pictures Home Entertainment now available on the VUDU streaming service have added Dolby Vision HDR imaging. Amazon Video Now Offering Dolby Vision HDR Fans of the Amazon original series “Bosch” are getting an upgrade for season two, as Dolby Laboratories and Amazon are offering the new season in Dolby Vision High Dynamic Range on Amazon Video. CES 2017: LG, Dolby Release 4K Blu-ray Player LG Electronics and Dolby Labs announced the LG UP970 Ultra HD Blu-ray player, LG’s first 4K Blu-ray player with Dolby Vision high-dynamic range imaging to be made available later this year through a software updat Dolby and Top Victory Bring Dolby AC-4 to Market Targets 2017 for availability in consumer TVs. ‘Planet Earth II’ Gets 4K UHD Blu-Ray Release Date BBC Home Entertainment is giving fans to bring “Planet Earth II” home in 4K UHD Blu-ray starting on March 28 in the U.S. and Canada. Interra Systems Integrates Dolby Vision into Baton QC Expansion of Dolby support designed to boost HDR experiences. Sony Titles to Feature Dolby Atmos Soundtracks In a deal between Sony Pictures Home Entertainment and Dolby Laboratories, past and future titles from SPHE will be released with Dolby Atmos soundtracks.
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6 video games that need full-blown remakes The average video game player is 35 years old. We are decaying, slowly marching towards our maggot-ridden graves. Psi-ops headlines Midway cleared in Psi-Ops copyright case Midway’s been cleared of alleged copyright infringement involving 2004 game Psi-Ops, Kotaku reports. William L. Crawford II, a Californian screenwriter, filed against Midway in March 2007, pointing out similarities between his 1998 script for a movie titled Psi-Ops and Midway’s title, both of which feature similar plot devices, characters and naming. Mr Crawford II didn’t […] Get Psi-Ops for free On Gaming Today. Psi-Ops: The Mindgate Conspiracy was a 2004 Midway game that got plenty of good reviews at the time, and for some reason you can now download and play it for absolutely nothing. Incredible value. It’s Wednesday, so you may as well. Psi-ops latest
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Violinist.com - News & Advice - Interviews Laurie Niles Starling-DeLay Day Two: A Conversation with Itzhak Perlman May 30, 2007, 10:12 PM · NEW YORK - After teaching his master class at the second day of the Starling-DeLay Symposium on Violin Studies at Juilliard, Itzhak Perlman stayed to chat with Symposium participants, answering questions from Symposium Artistic Director, Brian Lewis. "What first attracted you to the violin?" Brian asked. Perlman said "I heard the violin on the radio, and I love the sound." He said he loved the recordings of the greats such as Jascha Heifetz, Alfredo Campoli, Ida Haendel, David Oistrakh, and Isaac Stern. "What about Heifetz did you like?" Brian asked. "Oh, just that he was God," Perlman deadpanned. "He had so much character in his playing; it was so individual." Brian asked Perlman if he thought it was important to listen to recordings, and Perlman said that "the danger comes in listening to just one recording." For example, he's encountered a number of "Heifetz victims" in his life, even one "Milstein victim." "They need an exorcism!" Perlman said. "Victims take the obvious idiosyncrasies about (their idol) and magnify them." Perlman said he doesn't like to demonstrate much for students, as he doesn't want them to become imitators. When Perlman came to America at age 13, his first teachers were Dorothy DeLay and Ivan Galamian. DeLay was much different from the strict, Russian-trained teacher he'd had in Israel. For example, DeLay "believed in involving the student in the decision-making about music." "She would say, 'Sugarplum, what are you missing here? Where are the sequences?' or 'Sugarplum, what's your concept of G#?" Galamian cut more to the point. "IT'S OUT OF TUNE," Perlman said, in Galamian's Russian-flavored accent. "Galamian was able to take people who were moderately talented and make them play well," Perlman said of his mentor. Though he studied with both, "I worked harder for him than I did for her, because I knew she wouldn't KILL ME." (Cue audience laugh track....) Galamian had a deep concept of what makes a sound, what is at the core of the sound. On the other hand, DeLay "taught me how to think musically," Perlman said. "The way I teach -- a lot of it is inspired by her example." "Any experience you can have teaching will improve your playing," Perlman told the audience. "When you teach, listening is the number one quality you need." Brian asked Perlman what his most challenging performance was. Perlman said he could remember some memory slips. "I had a couple where I actually composed a piece," Perlman said. "For about 10 seconds I composed a piece---10 VERY LONG seconds...." Perlman imitated the bewildered conductor, then imitated himself -- lost but improvising. An audience member asked if Perlman recommended a specific practice regimen. Perlman said no, but "I recommend not over-practicing." After five hours, the brain loses its capacity to absorb anything, he said. "Don't practice blindly. You have to have a reason to practice," something particular to accomplish. "Put as much music into your practicing as possible," he said, so it is not all technical work. "Technique must make a connection with the music you are making." Also, practice in rhythms. "Get really used to one rhythm, then destroy it with another." One teacher asked him how he can play in tune so well with such large fingers. "Well, I'M TALENTED," he said, drawing more laughter. "No no. Look, it's difficult," he said. "Each finger, I sort of push the other away. Sometimes I play four notes in a row with the same finger. I believe every note has its own house up there." Asked about the importance of chamber music, he said, "Chamber music, for me, is the essence of everything that is right in music. Being able to breath with other musicians, being able to work as one with other musicians." "If someone is good at chamber music," he said, "They can do anything they want to do in music!" Efrem Violin May 31, 2007 at 09:13 AM · I certainly would like to have read some comments about other string players and conductors with whom Mr. Perlman has worked (or played). He must have some wonderful memories. Oh my, to have had just a few minutes with him. AND, what has he to say about the new crop of string players coming along? They seem to accomplish so much in such a short time. (Judy Kang, for example, and Sarah Chang), And, there was a Michelle, on the Westside, here in Los Angeles, that I heard play Tschaikovsky. I was spellbound. Her last name escapes me, (she was Asian!) but it seems I remember her stopping playing. It THAT were true, the world lost a real talent. I remember, I would say, "Look out, world, here comes Michelle, and her last name. (Can't seem to remember it.) Efrem Christian Vachon May 31, 2007 at 01:00 PM · Hi, Now this interview has GOOD advice! WOW! Lauren Canitia May 31, 2007 at 02:31 PM · Laurie, Thanks so much for sharing this! I have enjoyed reading your blog from the Starling-DeLay Symposium. Rick Barker May 31, 2007 at 09:12 PM · Great stuff! I particularly like what he says about the association of technique and music. Eugene Chan May 31, 2007 at 09:29 PM · "If someone is good at chamber music," he said, "They can do anything they want to do in music!" So true. It's all about listening. Amy F. May 31, 2007 at 10:12 PM · Great blog, Laurie! I love Perlman's playing, and his advice is great. I'm enjoying your coverage of the symposium. Keep it up!! :) Lei Zhang June 3, 2007 at 04:51 AM · Great job! I enjoyed to read very much! Please keep up your nice works! This article has been archived and is no longer accepting comments.
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Personally Identifiable Information: HIPAA Best Practices By Rob McDonald | Compliance | Healthcare For most healthcare organizations, protecting patient privacy is the most important aspect of HIPAA, and the most difficult. HIPAA uses the term Protected Health Information (PHI) to refer to protected data, but the concept is very similar to the term Personally Identifiable Information (PII), which is used in other compliance regimes. Understanding how PII and PHI overlap can help organizations unify compliance efforts across regimes, reducing the risk, cost and complexity of keeping data safe. PHI vs. PII: As the name implies, personally identifiable information is any data that can identify a person. Certain information like full name, date of birth, address and biometric data are always considered PII. Other data, like first name, first initial and last name or even height or weight may only count as PII in certain circumstances, or when combined with other information. For example, a record that referred to “Mr. Smith in New York” would be unlikely to contain enough information to give away the subject’s identity. If the patient had a less common name and lived in a small city, however, it would probably count as PII, since it would be easy to deduce who the subject was. Although it doesn’t explicitly address personally identifiable information, HIPAA regulates situations like this under the term Protected Health Information. PHI includes anything used in a medical context that can identify patients, such as: PHI is subject to strict confidentiality and disclosure requirements that don’t apply to most other industries in the United States. In other words, protecting PHI is always legally required, but protecting PII is only mandated in some cases. Developing a Unified Compliance Approach The United States is unusual in having no single privacy and data protection standard or government entity. Instead, American companies face industry-specific laws, along with city, state and international compliance regulations. Although this allows many industries to use consumer data more extensively, it also creates serious compliance risks. For example, because California has tougher PII laws than other states, a company that legally tracks users from Nevada when they visit its website could breach compliance if a Californian surfed in. Although PHI requirements are strict, a HIPAA compliance checklist won’t necessarily address PCI, EU data protection laws and other regulations. Rather than developing individual programs for each regime, organizations should implement PII security best practices across the board, then iterate to meet remaining, regime-specific rules. Auditing PII: Developing Compliance-Ready Security Good security starts with identifying PII across your organization, whether it’s in medical databases, email, backups or a partner’s IT environment. PII then needs to be categorized by how much harm a breach could cause — a measurement known as the confidentiality impact level. The NIST recommends considering the following factors: Identifiability: Is it easy to uniquely identify the individual using the PII? Quantity of PII: How many identities could be compromised by a breach? The way your data is organized is a factor. For example, a clinic would likely have more PII at risk if it shared a database with allied clinics than if it maintained a separate database. Data Field Sensitivity: How much harm could the data cause, if breached? A phone number is less sensitive than a credit card or social security number, for example. However, if a breach of the phone number would most likely also compromise name, SSN or other personal data, that phone number should be considered sensitive. Context of Use: Does the way the information is used affect its impact? For example, imagine your hospital had an opt-in a newsletter to patients, doctors, organizations and other community members. A list of newsletter subscribers would contain the PII of some patients, but that info would be less sensitive than the same PII in patient medical records, since it wouldn’t necessarily indicate patient status. Obligations to Protect Confidentiality: What information are you required to protect under HIPAA, HITECH, PCI and other regimes? This is obviously a key consideration for healthcare organizations. Access to and Location of PII: The personally identifiable information HIPAA governs is often stored, transported and processed by third party IT services, accessed offsite by medical professionals who aren’t employees of the organization and processed by a variety of business associates. This creates risks that wouldn’t be present, for example, if the PII were locked in a vault, and could only be accessed by one doctor. Implementing PII Security Best Practices Any data you store is potentially vulnerable. Collecting less data and purging unnecessary PII from your records is the easiest way to reduce that vulnerability. You should also de-identify data where possible. When done properly, measures like anonymizing patient feedback and remove or tokenizing PII can take that data out of the scope of HIPAA entirely. Access control is another valuable PII security best practice. Sensitive information should only be accessible by people who need it to do their jobs. For example, front desk staff that don’t handle billing, don’t need access to complete medical records. In any compliance regime, all sensitive information should be encrypted by default. HIPAA compliant email and encrypted cloud storage prevent hackers from deciphering PII, even if they intercept it. Explicit policies and regular trainings can help ensure your workers use secure email and storage, but getting patients to use email encryption is trickier. Many balk at the inconvenience of healthcare portals, leading to very low adoption rates. Virtru Pro allows patients to use their own email accounts and encrypt messages and attachments with a single click, removing the inconvenience that prevents meaningful use. Beyond Personally Identifiably Information — HIPAA Business Associates HIPAA goes beyond PII security best practices in its requirements for partner organizations. Under the HIPAA privacy rule, health care providers have considerable legal liability for breaches caused by business associates. Cloud services, contractors, medical claim processors and most other organizations which use, store or process PHI all count as business associates. You need to sign Business Associate Agreements (BAAs) with each of these organizations, describing: Appropriate use of PHI Safeguards for protecting breaches Steps to remediate breaches and violations Breach notification procedures Your organization should evaluate business associates carefully to ensure they’re actually capable of holding up their end of the bargain. Organizations should have clearly documented data security policies and practices in place before they sign a BAA, and should voluntarily undergo regular audits to ensure compliance. Beyond Personally Identifiably Information — HIPAA Notices and Notifications HIPAA also has strict requirements for how health information can be used and disclosed, and requires a notice of privacy practices be provided to the patient. The notice of privacy should cover a range of information, including: How the organization can use and disclose the patient’s information The patient’s rights The organization’s duty to protect the information, and other legal duties Who the patient should contact for more information HIPAA also has specific rules for breach notification. Under HIPAA compliance best practices organizations must notify anyone whose data has been compromised within 60 days of the breach. Making sure your partners use encryption is crucial. Encrypted data is exempt from breach notification, unless the key is exposed as well. In many cases, this can make the difference between a close call and a costly breach notification. Following PII security best practices helps organizations err on the side of caution. HIPAA isn’t a set of arcane and arbitrary rules to make your life difficult — it’s a useful framework to ensure a high standard of care and confidentiality for your patients. A PII best practices approach simplifies compliance by turning it into a single set of rules that can be used across your organization. That makes it easier to keep patients safe, and ensure sensitive information doesn’t fall through the cracks. Learn how Virtru protects HIPAA compliance in the cloud or contact us to set up a demo. K-12 Student Data Privacy Laws — From Past to Present Educate the Educators — A Lesson in Training Teachers and Staff to Protect K-12 Student Data Managing Manufacturing Data: How to Protect IP and Achieve NIST 800-171 Compliance Stay Up to Date With the Latest in Digital Privacy
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On selected days throughout the year we run our heritage freight train in addition to our standard steam service. The Freight Train will be running on the following dates: Sunday 15th September Our fantastic 1960 freight train will be operating in addition to our standard steam service. You can ride in the Queen Mary brake van for a donation. Watch a short film of our freight train running through Ropley station here. Virtually every railway station in the country had its own goods yard with a daily goods train bringing in coal for the local coal merchants to deliver to our homes, new agricultural equipment and fertiliser for local farms and taking out the produce to markets in London and beyond. Butter, timber, beer, cattle, fruit, grain, wine, meat, oil, manure, cement, chocolate, watercress and almost anything else you can think of was carried by the local goods train. At the Watercress Line we have our own wagon restoration group who have restored and maintain around 30 wagons, plus containers - you can keep up to date with all their news here. Our freight train aims to be typical of those circa 1960, even down to the packaging straw and shunters marks in chalk! Watch a film about the Wagon Department. June 1st 1964 saw the formal withdrawal of freight facilities from Alresford and Medstead stations, and with facilities at Ropley and Itchen Abbas withdrawn in 1962, this saw the end of the traditional "pick up” freight over the Mid Hants; with the exception of Alton and the short remaining branches to Treloars and Farringdon which lasted until 1968. See an article from the Mid Hants News Find out more about our freight train
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Darol L Anderson November 3, 1929 ~ June 16, 2019 (age 89) Darol L Anderson, 89, of Georgetown, passed away on Sunday, June 16 at home with family at his side. Darol was born November 3, 1929 in LaCrosse Wisconsin to John and Avis Anderson of Houston, MN. He graduated from Houston High School in 1946. He was a Staff Sergeant in US Air Force serving 6 years. He married Donna Jauken on February 19, 1956. He had a career with USDA working most of that time at Townsend’s in Millsboro and retired after 33 years. Darol was a loving husband, father, and grandfather. His priority and happiness in life was to see his family happy and cared for. He loved visiting and especially hosting relatives. He liked music, bowling, fishing, and reading. He was preceded in death by his wife of 60 years, Donna, his son David, Sister Betty Ask, and Sister Donna Shroeder He is survived by his son Danny and wife Sheila of Frankford; granddaughter Allison and companion Matt of Millsboro; grandson Brooks and wife Kate of Wilmington NC; and daughter in law Mary of Millsboro; and many nieces and nephews. A Chapel service will be held June 21, 2019 at 11:00 AM at the Delaware Veteran’s Memorial Cemetery, 26669 Patriots Way Millsboro, DE. In lieu of flowers the family suggests donations to Delaware Hospice, 100 Patriots Way, Milford, DE 19963. Electronic condolence via www.watsonfh.com DELAWARE HOSPICE 100 PATRIOTS WAY, MILFORD DE 19963
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Holidays at the Magic Kingdom PHOTOS - Holidays get underway at the Magic Kingdom complete with Christmas Tree Nov 04, 2015 in "Holidays at the Magic Kingdom" Forum Forums Tweet Share Share Tweet Share Share Gallery / 19 Photos Holidays decorations at the Magic Kingdom 2015 The holiday season is officially underway at the Magic Kingdom with Main Street U.S.A. now fully decorated. Unlike previous years, the Christmas Tree in Town Square is already in place. The park usually has to wait for the conclusion of the ABC Christmas Day Parade filming later in early December before the tree is installed. This is the first year that the new Main Street Plaza Gardens and the new hub walkways are open for the holidays. While not heavily decorated, there are some new pieces to see. Click the gallery for more photos. Article Posted: Nov 04, 2015 / 10:00a EST More from "Holidays at the Magic Kingdom" New Year's Eve 2018 entertainment line-up at Walt Disney World Magic Kingdom's holiday entertainment begins during regular park hours tomorrow PHOTOS - The Magic Kingdom's 2018 Christmas Holiday decorations Christmas Holidays decorations at the Magic Kingdom 2018 Nov 07, 201817 photos ABC's Primetime Special 'The Wonderful World of Disney Magical Holiday Celebration' Nov 17, 20171 photo Holiday Wishes New Year's Celebration 2015 Dec 31, 201515 mins Celebrate the Season Mickey's Once Upon A Christmastime Parade Nov 17, 201417 mins Impacts to entertainment during Disney Parks TV Specials production Performer line-up announced for the ABC and Disney Channel Holiday Season TV Specials Dates set for filming the 2018 ABC Holiday Specials at Walt Disney World PHOTOS - Castle Dreamlight installation nears completion at the Magic Kingdom NEWS / 1 year ago Christmas Holiday Season line-up announced for Walt Disney World 2018 New Year's Eve 2017 entertainment line-up More details on the upcoming ABC Primetime Special 'The Wonderful World of Disney Magical Holiday Celebration' New Made with Magic 3.0 Connected Ear Hat now available Shooting the ABC TV specials at the Magic Kingdom with Julianne Hough and Nick Lachey Preparations for the ABC TV specials at the Magic Kingdom 2016 The Disney Parks Magical Christmas Celebration Dec 23, 20162 photos Mickey's Most Merriest Celebration show
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Best Friends Pet Care Resort now taking reservations for August 27 2010 Jun 24, 2010 in "Kennels" LAKE BUENA VISTA, Fla., June 24, 2010 – Pet lovers visiting Walt Disney World Resort can now plan to board the family pet in fun, luxurious new accommodations. Reservations are being accepted for pet boarding stays beginning August 27, 2010 for the new Best Friends Pet Care Resort. The one-of-a-kind resort comprises more than 50,000 square feet of indoor and outdoor space, including 17,000 square feet of air-conditioned indoor space, 10,000 square feet of covered outdoor runs and play areas, and an expansive private dog park exclusively for the use of pet resort clients and their dogs. The facility will accommodate up to 270 dogs and 30 cats for both daytime and overnight boarding. A wide selection of suite choices for dogs includes air-conditioned indoor rooms, 48-square-foot indoor-outdoor suites, and four expansive VIP (very important pet) suites with television, raised bedding and private outdoor yards. Feline guests will spend their visit in the separate “Kitty City” pavilion -- away from the dogs -- in two and four-room condos. All suites and condos are designed to provide comfort and privacy and will be cleaned daily with hospital-grade disinfectants. “Best Friends has long been the industry leader for boarding, and this will be our crown jewel. We’ve taken the ‘best of breed’ in every category to create the perfect environment for pets,” said Dennis Dolan, President and CEO of Best Friends Pet Care. “Our goal is to ensure that pets staying with us have a fun, action-packed vacation – just like their families vacationing at Walt Disney World.” The resort’s exclusive dog park features a fenced walking trail bordering the natural wetlands around the park. Inside the trail, guests can choose from a variety of different play areas, including a 3,300 square-foot area covered in artificial turf, a 4,500 square-foot area with shade trees, and a 1,300 square-foot “canines only” water park. There are several large areas for owners to sit, relax and watch their dogs play. The entire park is secured from outsiders and is illuminated for use after dark. Other features of the resort include: a grooming salon, which will provide go-home-fresh baths and haircuts for pets; two 1,100 square-foot “camp rooms” for play group and doggy day camp, each opening onto an outdoor play-yard; and a special facility for the boarding of “pocket pets,” such as hamsters, guinea pigs, rabbits and ferrets. Pet parents can choose from a wide range of a la carte activities for pet guests from one-on-one playtimes and social playgroup with other doggy guests, to cuddle time and bedtime stories with staff. Additional amenities and upgrades include Ice Cream Treats, Bottled Water and Premium/Orthopedic Bedding. Feline guests can also enjoy private playtimes, activity toys in their suites, and treats such as Cookies and Milk or Tuna on a Ritz. The pet resort is located across from the Port Orleans Resort at 2510 Bonnet Creek Parkway in Lake Buena Vista, FL 32830. Pricing and other details are available at wdw.bestfriendspetcare.com or by calling 877-4-WDW-PETS. About Best Friend Pet Care Best Friends Pet Care Inc. (www.bestfriendspetcare.com) is a long-time leader in the U.S. pet hospitality industry, providing high-quality boarding for dogs and cats as well as day care, grooming, training and related services. Founded in 1991, the Company redefined pet boarding in 1996 with the opening of its first full-service pet resort in Norwalk, Conn. Since that time, Best Friends has expanded to more than 40 pet care centers in 18 states, always innovating and providing new offerings based upon the needs of pets and feedback from clients. The company currently operates the five boarding kennels at Walt Disney World Resort, which will be phased out with the opening of the new pet resort. Article Posted: Jun 24, 2010 / 3:16pm EDT More from "Kennels" Best Friends luxury pet resort opening day Sep 01, 20104 photos Best Friends Opens Luxury Pet Resort at Walt Disney World Resort Latest look at the Best Friends luxury pet facility construction Best Friends luxury pet resort construction Aug 25, 20104 photos Best Friends Pet Care opening slightly delayed to September 1 2010, with existing kennels to begin closing that day Best Friends Pet Care Resort fun facts Jul 08, 20102 photos Best Friends luxury pet facility construction photos Five existing in-park kennels to close when new facility opens this summer? Jan 15, 20106 photos 'Best Friends luxury pet resort' now under construction opposite Port Orleans Riverside NEWS / 12 years ago New WDW Kennel pricing and additional details
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College-Bound Colorado How much May 1 actually matters Here's what to do if you're still feeling indecisive about college after Decision Day. You’ve got a lot to worry about right now. Making a final college decision doesn’t have to be one of them, even if you’re hearing a lot about the May 1 "deadline" (even from a stellar little research university in Northern Colorado). Case in point: Jason, an aspiring English major in eastern North Carolina, thought he wanted to go to a big state university just down the road from his home when he was a high school senior. He applied, got in and bought a bright red sweatshirt. But within a month of his high school graduation, the desire to go farther afield grabbed him. Was it too late? The truth: not at all. If you, like Jason, have a change of heart or find yourself dreaming of a new school post-May 1, take heart. For some of the oldest and most prestigious colleges and universities, the May 1 deadline represents a firm decision date. But many places are actually more flexible. The great majority of colleges and universities in the United States are still working with students during the summer, figuring out financial aid packages, reviewing updated test scores and making admission decisions. This year, the college and university timeline is especially off because the federal government released its Pell grant charts (which tell schools how much federal financial aid they can give certain students) much later than usual. So many colleges and universities are still making financial aid offers, and they don't expect students to make a final decision before they know how much aid to expect. So if you're like Jason, or anyone else still trying to figure out college plans, what does this mean for you? If you can't decide before May 1, call an admission counselor or the admissions office at the school you're interested in. Ask what kind of flexibility you have in making your decision. Keep in mind that your admission decision might have to be made before you can sign up for housing. That means that if you decide later, you might have to be more flexible with which residence hall you end up in. If you still haven't applied, there is a chance — believe it or not! — that the college you're looking at is still accepting applications in May and even throughout the summer. See if you can log in to the online application and submit an application, and follow that up with an email or phone call to an admission counselor. What about at UNC? Confirming: Finalized financial aid packages for UNC students admitted before mid-April will all be arriving in mailboxes (and email inboxes) in early May — yes, post-May 1. While students will want to confirm as early as they can to secure popular housing and orientation slots, UNC typically has a percentage of students still confirming post May 1. If that’s you, not to worry. Applying: Like most other state universities nationally, UNC is still reviewing and accepting applicants over the summer. If you haven’t applied, there’s still time. Tours: Students can tour campus throughout the summer, even with an application under review or after being admitted. Schedule a tour at any time via our visit website. College Decision Parting wisdom from a college senior "What I'd tell my younger self" Tweaking your truth detector for college Chromebooks and college: Do they mix? What does undergraduate research really look like? AmeliaBuzzell (4) AmeliaConti (1) CampusLiving (6) CollegeDecision (2) CollegePrep (7) CollegeSearch (4) DeborahMoors (1) FinancialAid (3) GraduateSchool (1) JasonKeller (19) LibbyHarrington (1) MacyJordahl (3) NatalieTanner (5) OliviaEllison (3) PepTalksWithNatalie (2) RebeccaDell (2) ShaynaDix (8) StudyAbroad (1) TheCollegeExperience (23) rss_feed RSS Feed Bear in Mind Podcast Page Last Updated: Today | Contact for this Page: Office of Admissions
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