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2018 Extravaganza
Year End Extravaganza: Chris Latta’s 20 Favorite Albums of 2018
by Chris Latta December 17, 2018 December 17, 2018 1
This is the tenth year I’ve made a top albums list. I’m certainly no elder statesman (fuck, I’m not even thirty yet), but I’ve learned a lot in the last decade. I’ve broadened my musical horizons and codified my selection process, but the biggest lesson I’ve learned is to never be self-conscious about the albums you choose. We all experience music differently from one another and everybody has personal reasons for their preferences. Lists like these should not be made to prove one’s superior taste, but rather to share our findings with others and see how their experiences compare. There are no wrong answers if you can explain them, and every year is a good year if you know where to look. We’re all here to learn about each other as well as ourselves.
But enough of that flapdoodle, here’s my twenty favorite albums of 2018!
20) Khemmis – Desolation
Khemmis rides the momentum of their growing success quite smoothly on Desolation. The classic metal influences and more extreme tinges mesh well with the band’s epic doom roots, and the more developed vocals and guitar harmonies are something to behold. It doesn’t appeal to me quite as much as 2016’s Hunted, but it deserves props for presenting the style more accessibly without watering it down. It’s an album that should sit well with literally any kind of metal fan.
19) Merlin – The Wizard
When I first looked at Merlin’s fourth album, I was enthralled with the instrumentation but wasn’t sure if the songwriting was quite on the same level. Now that I’ve had more time to digest it, I can say that there’s more to The Wizard than my love of horns in heavy metal. The riffs are groovy as hell and the flow between songs perfectly channels the feel of classics from groups like Hawkwind and pre-Dark Side Pink Floyd. Seeing how the band recently expanded to a sextet, I imagine things will only get quirkier from here.
18) Blackslash – Lightning Strikes Again
I’m gonna be honest with you about this album: It’s not that unique. The style doesn’t sound that different from the multitude of traditional metal albums that came out this year. But Blackslash did something for this album that few of their peers did; they remembered to make it fuckin’ catchy. The fact that Lightning Strikes Again features the most infectious A side I heard all year deserves to be applauded, as does the rock-solid musicianship backing it up. As much as I enjoy Firepower, this album truly captures the spirit of early 80s Judas Priest.
17) Yob – Our Raw Heart
Bands like Yob have always prided themselves on their music’s climactic highs and lows, but I’ve never heard a more emotional album in the style than Our Raw Heart. The album’s compositions may hit all the common tropes of the post-metal formula, but the painful performances make for an especially cathartic experience. Moments like the sixteen-minute minimalism of “Beauty of Falling Leaves” don’t seem like they’d work on paper, but the way it’s set up fixates your attention the whole agonizing way through. Plenty of groups find tragedy in death. Yob found tragedy in survival.
16) Forming the Void – Rift
Seeing how Forming the Void’s second album, Relic was one of my top picks in 2017, it’s nice to see them come back with another winner just a year later. Rift greatly benefits from a more straightforward style whether it be the punchy “On We Sail” or the crushing doom of its last two numbers, and the commanding yet melodic vocals only add to the awesomeness. The band has been getting more attention lately, and I truly hope that they’re on the edge of a breakthrough.
15) Fire Down Below – Hymn of the Cosmic Man
Space rock bands are a dime a dozen these days, but I can’t think of a band in the scene with more balls than Fire Down Below. Their second album certainly does its share of navel-gazing, but there’s just as much time devoted to ass-kicking heavy metal overdrive. Nothing ever feels too tripped out as the memorable hooks serve as strong breadcrumbs when one is navigating through the album’s surprisingly purposeful jams. Anybody who misses the attitude seen in bands like Kyuss or early Fu Manchu will surely get a kick out of this.
14) 1914 – Blind Leading the Blind
There’s no questioning the passion that was put into 1914’s second album on both musical and thematic elements. The omnipresent wartime samples and ominous release date highlight the Ukrainians’ dedication to their World War I aesthetic while the intermingling of doom, black, and death metal results in ungodly heaviness. War themes in metal are as old as the genre itself and it does my heart good to see such fresh perspectives still emerging from this hellish union.
13) Höstblod – Mörkrets intåg
Inspired by familial tragedy, Höstblod’s debut album is a fascinating blackgaze conundrum. An array of unorthodox instrumentation is utilized without falling victim to technical self-indulgence, and song structures are full of curveballs that only enhance the intensity on display. The lyrics are exclusively performed in Swedish, but their emotions hit hard without getting too overwrought. It’s hard to tell where this project will go from here considering its muse, but this effort deserves much more exposure.
12) Iron Void – Excalibur
With a theme centered around Arthurian myth and a slight production upgrade, it goes without saying that Iron Void’s first concept album is more ambitious than their first two full-lengths. However, Excalibur offers a grounded execution with a slew of catchy doom riffs and memorable vocal lines. The whole thing gives me classic Gates of Slumber vibes, and I sure won’t bitch about that. I don’t think other traditional doom fans will either.
11) The Skull – The Endless Road Turns Dark
The Skull’s second album is cut from the same cloth as 2014’s For Those Which Are Asleep. But instead of feeling like a re-tread, it’s arguably more cohesive, with its various elements more thoroughly integrated. Plodding doom, ominous psychedelia, and even hints of blues are blended together quite smoothly thanks to skillful songwriting and Eric Wagner’s world-weary wail. It’s a laid-back listen without getting too soft, and engaging without getting too in your face.
10) Sergeant Thunderhoof – Terra Solus
Sergeant Thunderhoof’s second album is a distinct take on proggy stoner doom. Its crackly guitar tone, emphasis on groovy segments, and softer atmospherics help to set them apart from the bulk of their amp worship brethren. It offers a certain rawness not commonly seen in the genre and its memorable riffs make it worth coming back to. It’s the meeting ground between Orange Goblin and Porcupine Tree that I didn’t know I wanted but am happy to have.
9) Judicator – The Last Emperor
The Last Emperor is shorter than Judicator’s past efforts, but it never holds back on bombastic power metal goodness. Song arrangements are theatrical, as charging guitars and over the top vocal layers tell tales of well intentioned but fundamentally flawed crusaders of lore. Structures are elaborate, but the choruses are guaranteed to get stuck in your head. Some may find it too derivative of classic Blind Guardian, but you’ve got to be doing something right if Hansi himself shows up on a song!
8) All Them Witches – ATW
Having slept on 2017’s Sleeping Through the War, I was quite impressed with ATW. All Them Witches hasn’t altered their fuzz blues formula all that much but injecting some 70s rock swagger into it does give their signature jams more impact. As somebody who’s been following them since Lightning at the Door, it feels like the band is really starting to live up to their potential. I’m anxious to see where they go from here, especially considering their recent decision to ditch the keyboards and move to a power trio format.
7) Voivod – The Wake
Target Earth and the Post Society EP may have proved that life after Piggy was possible for Voivod, but I don’t think anybody expected The Wake to be this legitimately stunning. Despite only featuring half the original lineup, the band has crafted an album with a refreshing take on their classic sound. Chewy and new bassist Rocky play off each other well, Snake’s vocals have never sounded better, the classical strings are expertly applied, and the recurring motifs result in a cohesive concept album. An illustrious example to follow for the old guard and the new.
6) Pale Divine – Pale Divine
In a time when every doom/stoner band’s presentation is stuffed with fancy toys or important stories to tell, it’s nice to see a group that exists to just rock out. Pale Divine’s self-titled album is the definition of unpretentious with its basic instrument setup, working-class vocals, and forty-six-minute runtime. But rather than sounding monotonous or lazy, it excels thanks to heavy helpings of memorable grooves, varied songwriting, and catchy hooks. It’s not trying to be important but don’t confuse that for a complete lack of trying; this is an excellently crafted album that any doom fan should enjoy.
5) Mos Generator – Shadowlands
For all the time I spend mulling over subgenre nonsense, Mos Generator is one band I’m content to call straight up rock ‘n’ roll. Shadowlands is an excellent summary of their sound, combining the attitude of Electric Mountain Majesty with the chorus friendly Nomads and the trippier aspects of Abyssinia. It’s a heavy record with a lot of muscle behind it but also a certain polish that lends itself to lean hooks. If you’ve never heard the band before and have any fondness for Sabbath, KISS, or Floyd, this just might be the best place to start.
4) Witchkiss – The Austere Curtains of Our Eyes
Few albums in 2018 took me on a journey quite like Witchkiss’s debut. It starts as what seems to be a typical sludgy death-doom record only to reveal itself as a more multi-faceted affair with a stirring dual vocal format and dynamic riff work, all the while retaining a dark cavernous atmosphere. It’s very purposeful for a first entry, and I’m curious to see how the band will develop from here. I can tell you that seeing the band perform at this year’s Doomed & Stoned Festival in near pitch blackness and a storm raging outside was one of the most thematically appropriate live sets I’ve ever witnessed.
3) Wayfarer – World’s Blood
Wayfarer’s third album is a very striking take on atmospheric black metal. Its bright, dry tone and sprawling lengths capture the open desolation of the American badlands while the pounding riffs on songs like “Animal Crown” and “The Crows Ahead Cry War” give them more muscle than your average Agalloch clone. 2018 seemed to be a year for western-themed black metal bands to make themselves known, and while any widespread movement is likely a product of my own imagination, these guys make for strong trailblazers.
2) Wolftooth – Wolftooth
2018 seemed to be the Year of Wolftooth. The Richmond, Indiana group came the right hell out of nowhere, instantly getting on huge supporting bills and earning endorsements from various factions in the underground. My girlfriends enjoy them, and they’ve attracted the attention of people not normally attuned to newer bands. And the best part is that they deserve every bit of praise they get. Their debut album is a perfect meeting ground of doom and classic metal, offering a slew of powerful riffs and catchy vocals that only get stronger with repeated listens.
1) Visigoth – Conqueror’s Oath
Visigoth’s second album is the perfect balance of epic and fun. Despite being nearly twenty minutes shorter than its predecessor, 2015’s The Revenant King, it features much of the same dramatic riff work and the vocal layering makes its choruses as climactic as they are infectious. The leaner song lengths result in a barrage of hard-hitting anthems, and songs like “Outlive Them All” barely give you time to truly absorb them yet never fail to make deep impressions. It also helps that Jake Rogers’ baritone is the most refreshing voice in contemporary metal. Some may deny the album a classic status, but it wouldn’t surprise me if it proved influential to future bands.
19142018All Them Witchesbest ofBlackslashFire Down Belowforming the voidHOSTBLODIron VoidJudicatorKhemmisMerlinPale DivineSergeant ThunderhoofThe SkullTop AlbumsVisigothVOIVODWayfarerWITCHKISSWolfToothYob
Live Review: Steel Panther, Wilson, DJ Wrathchild
Year-End Extravaganza: Clayton’s 20 Favorite Albums of 2018
Chris Latta
I went to Ball State University and graduated with a BA in Creative Writing. Currently specializing in writing album reviews when I should be working at my day job. My Grading Scale A: An essential classic regardless of genre preference B: A good album recommended to fans of a given genre C: A flawed album with elements that are still enjoyable D: A dull album that may only be redeemable for fans F: It is a goal of mine to never review an album like this I also play in a couple different bands and take it as much as I dish it out. Feel free to check them out! http://spiritdivision.bandcamp.com http://lavaborne.bandcamp.com http://christophersteve.bandcamp.com
Top 20 Albums of 2019: The Latta Edition
Chris Latta December 12, 2019 December 12, 2019
Video Premiere: Merlin – “Chaos Blade”
EP Review: Mangog – The Ghost in the Room EP
Chris Latta June 19, 2019 June 17, 2019
EP Review: Visigoth – Bells of Awakening
Goniloc Ripal May 21, 2019 May 19, 2019
Short Sharp Shock #37: The Heaviest of Metals and the Hardest of Rocks
Nigel Holloway May 8, 2019 May 4, 2019
Matt S. December 17, 2018 at 10:06 am
Great opening paragraph that I wholeheartedly agree with!
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This page:UHH > MIN > Department of Informatics > Institutes > Research groups > Language Technology Group > Resources > Data > Blurb Genre Collection
The BlurbGenreCollection-EN is a dataset consisting of advertising descriptions of books - so called blurbs - for the English language. Each blurb is categorized into one or multiple categories. The categories are structured hierarchically. This dataset follows the policies as described in the RCV1 dataset by Lewis et al. (2004). We adapt RCV1's properties, which have been explained by its authors in detail and refer to their description. The minimum code policy requires the assignment of at least one category to each document of the collection. The hierarchy policy ensures that every ancestor of a document's label is assigned as well.
The copyright to all blurbs belongs to Penguin Random House (PRH), its licensors, vendors and/or its content providers since the blurbs were obtained through the penguinrandomhouse.com website. The blurbs serve promotional/public purposes and permission has been granted by Penguin Random House to share this dataset.
The Penguin Random House webpage lists every book with its respective blurb. We extracted the 'about sections' as well as the genres (category) of a book. We further extracted title, author, url, ISBN, number of pages and the date of publication. The date of publication normally represents the publication date of the particular version of the book. The data we extracted is illustrated below.
Penguin Random House: Link, accessed on 14.10.18
Since the webpages only lists the most specific genre, we manually created the hierarchy for writing genres and add all parent labels during post-processing. Further pruning was done to remove genres that capture properties which do not rely on content but on the shape or form of a book. From the Childrens' Book category, three out of ten sub-genres were kept as most of them specify the presentation and shape of a book and not the content. For example 'Picture Book', 'Boxed Sets', 'Board Books' and so on. The genre Audiobooks and all its descendants were removed as well for obvious reasons. As the last preprocessing step, we remove every book that has assigned genres (combinations) that appear less than five times in the complete dataset.
An example entry of the resulting datset is shown below:
<book date="2018-08-18" xml:lang="en">
<title>2001: a Space Odyssey</title>
The classic science fiction novel that captures and expands on the vision of Stanley Kubrick´s
immortal film-and changed the way we look at the stars and ourselves. From the savannas of Africa at the
dawn of mankind to the rings of Saturn as man ventures to the outer rim of our solar system, 2001: A
Space Odyssey is a journey unlike any other. This allegory about humanity´s exploration of the universe-and
the universe`s reaction to humanity-is a hallmark achievement in storytelling that follows the crew of the
spacecraft Discovery as they embark on a mission to Saturn. Their vessel is controlled by HAL 9000, an
artificially intelligent supercomputer capable of the highest level of cognitive functioning that
rivals-and perhaps threatens-the human mind. Grappling with space exploration, the perils of technology,
and the limits of human power, 2001: A Space Odyssey continues to be an enduring classic of cinematic
scope.
<copyright>(c) Penguin Random House</copyright>
<metadata>
<topics>
<d0>Fiction</d0>
<d1>Science Fiction</d1>
<d1>Mystery & Suspense</d1>
<d2>Suspense & Thriller</d2>
</topics>
<author>Arthur C. Clarke</author>
<published>Sep 01, 2000 </published>
<page_num> 320 Pages</page_num>
<isbn>9780451457998</isbn>
<url>https://www.penguinrandomhouse.com/books/325356/2001- a-space-odyssey-by-arthur-c-clarke/</url>
</metadata>
Additionally, a file that contains only the hiararchy in form of parent-child relationships is provided.
Quantitative characteristics
The datset is split into three subsets for training, validation and testing by appling stratified sampling to ensure that splits do not disfigure the distribution of labels. The total data is split in the ratio of 64%, 16% and 20% for train, dev and test respectively.
Summary of BlurbGenreCollection-EN
Number of samples
Average length of blurb
Total number of classes
Average number of genres per book
Classes on each level of the hierarchy
L1: 7; L2: 46; L3: 77; L4: 7
The hierarchy of the dataset consists of four levels and is organized as a forest. It is important to note that the most specific genre of a book does not have to be a leaf. For instance, the most specific class of a book could be Children’s Books, although Children’s Book has further children genres, such as Middle Grade books. However, a great number of books are simply not classified into more special classes on the website. Analyzing the occurrence of each genre combination on a log scale shows that the English dataset has a distribution in which some labels have disproportionately few or many examples as shown in the Figure below.
The dataset is used for a hierarchical multi-label classification task, where each label is part of a hierarchy. The baseline model that has been employed to classify books into their respective writing genre is the Support-Vector Machine (Cortes et al., 1995). The following results are created exclusively on basis of a book's blurb.
Classifier Results
Classifer
Subset Accuracy
blurb-genre-collection-en.zip
This dataset is redistributed under the creative commons license CC BY-NC.
Lewis, David D and Yang, Yiming and Rose, Tony G and Li, Fan (2004): Rcv1: A new benchmark collection for text categorization research, Journal of Machine Learning Research 5 (Apr), 361-397
Cortes, C. and Vapnik, V. (1995). Support-vector networks. Machine learning, 20(3):273–297.
Our application for a collaboration project betwen literary science and...
We happily announce that the second phase of the 2nd phase of Transregio-SFB...
Every two years the GSCL (German Society of Computational Linguists) awards...
A new publication from LT group member Gregor Wiedemann has appeared in...
Dr. Gregor Wiedemann from the Language Technology group of our department has...
We are happy to announce the release of version 2.0 of our software new/s/leak...
Our new article on local-global graphclustering with Watset has just been...
The 20th Conference of the International Speech Communication...
Seven papers in different categories from LT co-authors have been accepted for...
In this year's SemEval 2019 Task 2 on Unsupervised Lexical Semantic Frame...
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Teaching the Teachers
LGBTQ Issues in Teacher Education
Cathy A. R. Brant, University of South Carolina
Lara Willox, University of West Georgia
A volume in the series: Contemporary Perspectives on LGBTQ Advocacy in Societies. Editor(s): Joshua Moon Johnson, American River College. Lemuel W. Watson, Indiana University School of Education.
In Press 2019
Teacher educators have opportunities to include issues of multicultural education, equity, and social justice in the work done with preservice teachers. Including the educational and societal experiences of historically marginalized populations in curriculum creates spaces for teacher educators to model multicultural and social justice based pedagogies, while preparing teachers to work with and work for these students.
The most effective way for teacher educators to address the unique perspectives of historically and currently marginalized populations is to integrate various perspectives throughout the curriculum (Grant & Zwier, 2012). Most teacher education programs address diverse populations via an integrated approach. In fact, Sherwin and Jennings (2006) found that potential student experiences regarding social class, race, and special needs populations were typically integrated into the curriculum, however, lesbian, gay bisexual, and transgender (LGBT) issues were not. There is research that demonstrates how carefully planned and implemented educational interventions can have a positive effect on preservice teachers’ knowledge of and attitudes toward gays and lesbians (Butler, 1999).
Despite the positive impact of addressing LGBTQ issues as a part of the teacher preparation program, Gorski et al. (2013) found that LGBTQ issues receive significantly less class time than other issues, especially race, and are, in fact, eight times more likely to actually be omitted from multicultural teacher educator courses. The inclusion of LGBT topics is important for a myriad of reasons. Most importantly, studies (GLSEN & Harris Interactive, 2012; Kosciw, Greytak, Diaz, Bartkiewicz, 2010, 2012; Kosciw, Greytak, Palmer, Boesen, 2014; Kosciw, Greytak, Giga, & Danischewski, 2016) have revealed a negative school climate for students who identify as gay, lesbian, bisexual, or transgender; this hostile environment can have dire consequences for these students. The impact of bullying and harassment due to LGBTQ students’ gender and/or sexual identities can produce a number of negative effects, including isolation from friends and family, depression, drug and/or alcohol use and addiction, low selfesteem, lack of engagement in school, academic failure, and fighting (Beam, 2007; Holmes & Cahill, 2004; Kosciw et al., 2010, 2012; Kosciw et al, 2014; Kosciw et al, 2016,
Meyer, 2010; Wilkinson & Pearson, 2009).
The negative climate does not just come from peer-to-peer negative interactions. In the most recent GLSEN study (Kosciw et al, 2016) it was found that
• 57.6% of LGBTQ students who were harassed or assaulted in school did not report the incident to school staff, most commonly because they doubted that effective intervention would occur or the situation could become worse if reported.
• 63.5% of the students who did report an incident said that school staff did nothing in response or told the student to ignore it.
• 56.2% of students reported hearing homophobic remarks from their teachers or other school staff, and 63.5% of students reported hearing negative remarks about gender expression from teachers or other school staff
The aim of this book is to support teacher educators as they engage in the work of preparing pre-service teacher to work with and work for LGBTQ youth through explicit discussions of gender and sexuality. Chapters for this book include personal anecdotes regarding shifts in author’s thinking about including LGBTQ as a part of teacher preparation; specific pedagogical practices employed by authors to present LGBTQ focused material as a part of their coursework; the resistance authors have faced from students, parents and administration and their responses.
Introduction: Teaching the Teachers: The Need for LGBTQ Inclusive Teacher Preparation, Cathy A. R. Brant & Lara Willox. I Have Come to a Greater Knowledge of God and His Plan: The Affordances of Queer Pedagogy to Prepare Religious Preservice Teachers to Serve LGBTQ Students, Roni Jo Draper. Sharing Practices to Help Teachers Provide Supportive and Safe Classrooms, Judith S. Kaufman and Pia Ferrante. Unlearning Heteronormativity: A Framework for Talking About LGBTQI Children in Teacher Education, Peggy Shannon-Baker. Crusading into the Unknown: Finding and Using LGBTQ Primary Sources in Teacher Preparation, Leia K. Cain and Bretton A. Varga. Queering Stories with Pre-Service Teachers, Kimberly Cosier. (Re)Storying School Experience and Transforming Teacher Education: Writing a New Narrative for LGBTQ Students, Kathy Carter, Amanda T. Sugimoto, Kathleen J. Stoehr, and Griff Carter. Shifting from Knowing What to Knowing How: Centering Queer Knowledges and Activist Teaching Narratives in English Education, Ryan Schey. Queer Theory and the Social Studies: Engaging with Histories, Communities, and Identities, Mark Helmsing. Independent Queer: LGBTQ Educators in Independent Schools Speak Out, Philip McAdoo.
eBook978-1-64113-832-1
EDU053000 - EDUCATION: Training & Certification
EDU048000 - EDUCATION: Inclusive Education
EDU029070 - EDUCATION: TEACHING METHODS & MATERIALS: Health & Sexuality
Critical Issues in Early Childhood Teacher Education Volume 1 - US Perspectives
Culturally Responsive Pedagogy Promising Practices for African American Male Students
Linking Teacher Preparation Program Design and Implementation to Outcomes for Teachers and Students
Queer People of Color in Higher Education
Teacher Education at the Edge Expanding Access and Exploring Frontiers
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Philosophy and Religion >
Protestant Christianity: Biographies >
John of Leiden
John of Leiden, c.1509–1536, Dutch Anabaptist leader. His original name was Beuckelszoon, Beuckelzoon, Bockelszoon, Bockelson, Beukels, or Buckholdt. John of Leiden was attracted to the extreme left of the early Reformation movement through the influence of Thomas Münzer . In 1533 he joined the Anabaptists and, as a follower of Johann Matthyszoon (Matthiesen) moved to Münster. There in 1534 the Anabaptists took up arms and deposed the civil and religious authorities of the town. After Matthyszoon's death in the siege, John of Leiden assumed leadership and set up a theocracy in the new Zion. Soon John declared himself king, with Bernard Knipperdollinck second in command; during his brief and arbitrary rule general lawlessness prevailed, polygamy was legalized, and property communized. When the siege to recover the town, led by the expelled prince bishop, was successful in 1535, the leaders of the new kingdom of Zion were barbarously tortured and in the following year executed.
See more Encyclopedia articles on: Protestant Christianity: Biographies
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Cornucopia Launches New Digital Archive
Bi-annual magazine Cornucopia has joined forces with digital publishing platform Exact Editions to offer individual and institutional subscribers access to an archive of 15 back issues.
John Scott: “As we approach our 30th anniversary, it is heartening that this wealth of exclusive material will now be at the fingertips of a far wider audience.”
Cornucopia is a magazine for connoisseurs of Turkey. Covering history, culture, art, food and travel within its glossy pages, the publication is an ever-growing compendium of all things Turkish. First launched in 1992, the magazine has been described as ‘a cross between World of Interiors and National Geographic’ by Tyler Brûlé in the Financial Times, a portrayal that encapsulates the magazine’s blend of enlightening content and spectacular design, says Exact Editions.
The new resource is available cross-platform on web, iOS and Android. The archive includes a comprehensive search function, permitting users to instantly find a specific article, location or topic. Individual pages from the archive can be easily bookmarked, downloaded and shared digitally with fellow readers.
Cornucopia is available for individuals and institutions in the Exact Editions shops.
John Scott, editor of Cornucopia, commented: “We’re excited about the new opportunities that the digital edition will bring both individual and institutional subscribers, and the intuitive usability of the platform. For three decades we have focussed on all that is timeless and worth preserving about Turkey in fast-changing times with in depth, elegantly written and beautifully illustrated articles. Our back issues have always been considered an important resource. As we approach our 30th anniversary, it is heartening that this wealth of exclusive material will now be at the fingertips of a far wider audience.”
Daryl Rayner, Managing Director of Exact Editions, said: “The dazzling front covers and photographs featured throughout the publication look wonderful on the digital platform. The academic promise of the archive is clear now that subscribers can efficiently browse the wealth of fascinating content.”
Consumer media Supplier news
The Tablet releases full digital archive with Exact Editions
An eye for quality
Marie Claire appoints Purpose & Sustainability Advisor
New Editor-in-Chief for Vogue Russia
Fence launches digital archive
Hearst Magazines in Europe unveils new structure
DCT Media launches This Is Vlogmas!
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‘Killer Asteroids’ Hidden In Annual Taurid Meteor Shower? Scientists Have Detected Two, Fear More
Norman Byrd
After finding two massive asteroids with the potential to do extensive damage to the Earth in a previously undiscovered branch of the Taurid Meteor Shower, a couple of scientists are now warning that there could possibly be more of these Potentially Hazardous Asteroids (PHAs) hidden in the cometary debris field and they could very well be on a trajectory to collide with Earth in the near future.
The Daily Mail reported that researchers from the Astronomical Institute of the Czech Academy of Science have found two giant asteroids, 2015 TX24 and 2005 UR, in the debris field of what they are calling a dangerous branch of cometary fragments left behind by the passage of Encke’s Comet, which, according to Space, orbits the Sun every 3.3 years. And although those asteroids are listed as PHAs (both measuring from 200 to 300 meters — 650 to 900 feet — across) and are being tracked, it is the asteroids that have yet to be detected in the debris field, some of which become part of the Taurid Meteor Shower, that worries the Czech scientists.
The researchers published their findings — and fears — on Arxiv, stating in the paper, “Since asteroids of sizes of tens to hundreds meters pose a treat [sic, ‘threat’] to the ground even if they are intrinsically weak, impact hazard increases significantly when the Earth encounters the Taurid new branch every few years.”
The scientists figured out that Earth will interact with the dangerous branch of the Taurids in 2022, 2025, 2032, and 2039. (It should be noted that the Earth experiences a Taurid Meteor Shower every year in late October and early November.)
As Space.com pointed out, even though scientists have calculated that fragments of the comet could be of a size large enough to remain somewhat intact after the plunge through Earth’s atmosphere, an actual Taurid meteorite has yet to be found. In fact, Space.com referred to such a find as the “holy grail of meteorites.”
Scientists believe there just might be some hidden potentially hazardous asteroids among the space rocks and fragments that make up the Taurid Meteor Shower. [Image by 3000ad/Shutterstock]
But if the warnings of the researchers at the Astronomical Institute of the Czech Academy of Science bear fruit, it might just be only a matter of time before a hazardous asteroid loses its “potential” status and becomes and actual hazardous asteroid. The Daily Mail pointed out that the 1908 Tunguska Event was believed to have been caused by the passage and detonation of a Taurid meteor. That particular space rock is believed to have detonated in the air some six miles up in the atmosphere. Its blast was estimated to equal the energy of 185 Hiroshima atomic bombs, leveling some 80 million trees in remote lower Siberia.
The Czech researchers warned that if an as-yet undetected massive asteroid, a PHA, actually made it through to impact Earth, the results could be catastrophic. To put the Tunguska meteor in perspective, it has been estimated to have been about 45 meters (148 feet) across. The Inquisitr reported in March that in an earlier study conducted by InsuranceQuotes, it was calculated that an asteroid just slightly larger than the two detected by the Czech scientists, if it impacted the city of San Francisco, would result in the deaths of about 9 million people.
But the PHA would not have to be anywhere near that large to do extensive damage. It would simply have to make a direct hit on a densely populated urban area. In fact, potential impactors measuring 140 meters — 459 feet — and smaller are known as “city killers” by Congress, according to Stanford University physicist Richard Blandford (per Space News).
Any asteroid measuring over 100 meters (328 feet) is considered by NASA to be a PHA.
Almost all meteors burn up entering the Earth's atmosphere. [Image by Belish/Shutterstock]
It is estimated that there are less than 5,000 PHAs greater than 100 meters in diameter that exist in near-Earth orbit. However, it is believed that 20 to 30 percent of those asteroids that have yet to be found.
[Featured Image by Vadim Sadovski/Shutterstock]
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Posts Tagged ‘Kevin Kotler Broadfin Capital’
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June 11 - News - Comments
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June 4 - News - Comments
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April 25 - News - Comments
Do Hedge Funds and Insiders Love Cardionet Inc (BEAT)?
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Is Hi-Tech Pharmacal Co. (HITK) Going to Burn These Hedge Funds? – Sagent Pharmaceuticals Inc (SGNT), Momenta Pharmaceuticals, Inc. (MNTA)
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Here is What Hedge Funds Think About Depomed Inc (DEPO): Synergy Pharmaceuticals Inc (SGYP), SciClone Pharmaceuticals, Inc. (SCLN)
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April 9 - News - Comments
Here is What Hedge Funds Think About Insmed Incorporated (INSM): Threshold Pharmaceuticals, Inc. (THLD), Repligen Corporation (RGEN)
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Masimo Corporation (MASI): Insiders Are Dumping, Should You?: Wright Medical Group Inc (WMGI), CONMED Corporation (CNMD)
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Hedge Funds Aren’t Crazy About MAKO Surgical Corp. (MAKO) Anymore: The Spectranetics Corporation (SPNC), Symmetry Medical Inc. (SMA)
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March 31 - Hedge Funds - Comments
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Bora Bora Tahiti Overwater Bungalows: St. Regis Resort
Zach Stovall
Stay in an overwater bungalow in Tahiti. It's the No. 1 Wish on the ISLANDS Wish List 100. To prove why it's number one, photographer Zach Stovall chose these 15 amazing images from his Bora Bora bungalow stay.
"Like you, I'd seen the photos," writes photographer Zach Stovall in the Wish List issue of ISLANDS magazine. "In the weeks leading up to my first trip to Tahiti, all I could think about were those overwater bungalows. Staying in one has topped my wish list for at least 10 years."Zach Stovall
"I know how daydream travel rarely coincides with feet-on-the-ground travel. So somewhere between Los Angeles and villa 231 at the St. Regis on Bora Bora, I cool my expectations."Zach Stovall
"From a distance, the bungalows look surreal. The thatch makes them appear more natural than I expected."Zach Stovall
"The view from inside is as epic as the view from outside. Floor-to-ceiling windows offer a view of Mount Otemanu and the electric-blue lagoon. I also have a floor window, so I can watch the marine life in action — far better than watching a 52-inch HDTV."Zach Stovall
"My only concern is making sure I swim back to the right bungalow. The one that, even when I’m in it, still tops my wish list."Zach Stovall
"During my planning, one of the last amenities that came to mind was a swimming pool. And during my stay, I didn't use it. The lagoon off my porch was the best pool I've ever been in."Zach Stovall
"Maybe you don’t want to hear this, but it only gets better."Zach Stovall
"This is the water that I woke up in every morning, and relaxed in every evening."Zach Stovall
"It's a long walk back to the bungalow if you forget your key. The pitfall of living out over the sea."Zach Stovall
"At dawn, while waiting for breakfast to be delivered by outrigger canoe, I watch a steady stream of locals paddle to work. Their commute is serene, punctuated only by the sounds of paddle strokes. I step off the deck and land in the bathlike water."Zach Stovall
"I wrote down the drink recipes, but the truth is, my replicas don't have the most important ingredient: the Bora Bora atmosphere."Zach Stovall
"When I'm shooting on assignment it's rare for me to stay in one spot for more than a few minutes. When I took this shot, I'd been in the same spot for nearly two hours. And I stayed here until it was completely dark."Zach Stovall
"Yep, the resort has a beach, sun umbrellas, and drinks. Don't get me wrong, I love the beach. But sitting on one wasn't part of my ultimate wish."Zach Stovall
"If I could do it over again (and I will), I'd be here with my wife. Staying here solo is not the ideal way to go."Zach Stovall
To book a bungalow and see for yourself, visit the St. Regis Bora Bora resort website.Zach Stovall
More Pacific
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Nissan Homy Elgrand
Japan Used Nissan Homy Elgrand Camping Car for Sale
Year From 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 1985 1984 1983 1982 1981 1980
Year To 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 1985 1984 1983 1982 1981 1980
Steering Right Hand Left Hand
Min Mileage 5,000 KM 10,000 KM 20,000 KM 50,000 KM 100,000 KM 150,000 KM 200,000 KM
Max Mileage 200,000 KM 150,000 KM 100,000 KM 50,000 KM 20,000 KM 10,000 KM 5,000 KM
Price From 500 US$ 800 US$ 1,000 US$ 1,500 US$ 2,000 US$ 2,500 US$ 3,000 US$ 5,000 US$ 10,000 US$ 20,000 US$
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Last Update:2nd Aug, 2019
Nissan Homy Elgrand (1999) Now on Sale FOB : 8,990 USD
1999 NISSAN ELEGRAND CAMPING CAR POP UP ROOF GASOLINE A/T USA/Baltimore
AutoLink, Yamato, Japan | 185
Ref# JCT-3369141 (Stock ID: ALH35055)
Options:ABS | Power Windows | Power Mirror | Power Steering | Air Bag
Compare Remove Add to Cart Remove
The Homy Elgrand is passenger minivans produced by the Japanese automaker Nissan since 1997. It contained some features as the rigid body and impressive design of the grille, the body is equipped with 4 doors, two hinged, sliding door on the right side, tailgate and 3-rows of seats.
The interior is equipped with 3 rows of seats. Lineup engine borrowed from Terrano model, and therefore first vehicle raised on a 6-cylinder V-shaped gasoline engine with a displacement of 3.3 or 3.2 - liter diesel "turbo". The car had a front-wheel drive or equipped with all modes 4x4 systems. In 1999, the replacement of a small lineup was held, during which the old diesel engine gave way to his fellow new development, which has better performance and lower fuel consumption.
It was a 3-ex-liter turbo-diesel. As for the 6-cylinder petrol unit, in 2000, the engine cylinder capacity of 3.5 liters, two variants of the interior layout were provided 7 seaters and 8-seater. In some categories of cars sliding door has been translated into an electric drive, in the same way, and retracted step outside.
JapaneseCarTrade.com receives lots of Nissan Homy Elgrand Minivan inquiries every day from many countries. You can find hundreds of Nissan Homy Elgrand Minivan ready stock for buy. Please check list of all Nissan Homy Elgrand Minivan Exporters in Japan or send your inquiry to get best offers.
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International rugby coming to Port Elizabeth
Home Rugby International rugby coming to Port Elizabeth
Rugby 14 April 2011
Port Elizabeth has won the bid to host the South African leg of the HSBC Sevens World Series rugby tournament for the next five years.
The inaugural event will take place in early December this year. SARU said that Port Elizabeth went the extra mile to compile a bid that outshone the other cities.
Will South Africa win the IRB sevens title in Port Elizabeth? Photo: IRB
Across the Eastern Cape politicians and officials also celebrated. Sports, Recreation, Arts and Culture MEC Xolisa Tom said this coup was an achievement for the whole Eastern Cape.
“We are so excited,” said Tom. “We really feel that we deserved this win, it is long overdue because the Eastern Cape is a rugby playing province and so many of our young people play rugby. We want our province to be seen as a sports events destination.”
Cheeky Watson who has been instrumental in turning around the fortunes of rugby in the Eastern Province is also very upbeat about the decision.
“This is a very exciting moment for Nelson Mandela Bay and the entire Eastern Cape. We are all very well aware that this is the heart and soul of black rugby and we are extremely excited that SARU, the IRB and the sponsors have chosen this region as the South African leg for the World Sevens Series.
Between the IRB Sevens and inclusion in the Olympics, we expect Sevens Rugby to sky-rocket in the region”, said Watson.
The economic spinoffs are expected to total R 80 million per year and the media spin off is huge and bodes well for Jeffreys Bay too.
Jeffreys Bay Tourism wants to position the town as the base to explore the surrounding attractions and the IRB Sevens is a perfect fit for this vision.
Andy Thysman, CEO of Jeffreys Bay Tourism said that the town will market itself to visitors who will be coming to watch the rugby. “We are close enough to Port Elizabeth to take advantage of the spin off.
This is a wonderful opportunity for the entire province and we can show case Jeffreys Bay to a new market and look forward to a cash flow injection into the town in the early December when things are traditionally rather quiet”, said Thysman.
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Coalition talks: The DA will always put the people of Nelson Mandela Bay first
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JEANNIE VANASCO
Things We Didn't Talk About
The Glass Eye
“Hypnotic . . . a haunting exploration of perception, memory, and the complexities of grief.” — Marya Hornbacher, The New York Times Book Review
“Brilliant, obsessive . . . As the pages fly by, we're right by Vanasco, breathlessly experiencing her grief, mania, revelations, and—ultimately—her relief.” — Isabella Biedenharn, Entertainment Weekly
The night before her father dies, eighteen-year-old Jeannie Vanasco promises she will write a book for him. But this isn't the book she imagined. The Glass Eye is Jeannie's struggle to honor her father, her larger-than-life hero but also the man who named her after his daughter from a previous marriage, a daughter who died.
After his funeral, Jeannie spends the next decade in escalating mania, in and out of hospitals―increasingly obsessed with the other Jeanne. Obsession turns to investigation as Jeannie plumbs her childhood awareness of her dead half sibling and hunts for clues into the mysterious circumstances of her death. It becomes a puzzle Jeannie feels she must solve to better understand herself and her father.
Jeannie Vanasco pulls us into her unraveling with such intimacy that her insanity becomes palpable, even logical. A brilliant exploration of the human psyche, The Glass Eye deepens our definitions of love, sanity, grief, and recovery.
Indie Next Pick
Indies Introduce Pick
Barnes & Noble Discover Great New Writers Pick
Poets & Writers's pick for one of the five best literary nonfiction debuts of 2017
A Fall Pick at Powell's, Ploughshares, NYLON, Publishers Weekly, Entertainment Weekly, Amazon, Bustle, New York, Newsweek, and more.
“An intense and unforgettable memoir, as fascinating for its artistry as for its subject matter. . . . Lyric, haunted, smart and tortured, this is an obsessive love letter to a dead father as well as a singular work of literature.” — Julia Kastner, Shelf Awareness
“The language cuts quick to the heart of Vanasco’s hurt; readers will immediately fall into the rhythm of her unrelenting inner dialogue. . . . Vanasco's candor, curiosity, and commitment to human understanding are not to be missed.” — Courtney Eathorne, Booklist, starred review
“A deceptively spare life story that sneaks up and surprises you with its sudden fecundity and power.” — Kirkus Reviews
“In this powerful and ruminative memoir, Vanasco explores the years following her father’s death as her grief transforms into an increasing obsession with her half-sister Jeanne, who died before Vanasco was born. . . . An illuminating manual for understanding grief and the strange places it leads.” — Publishers Weekly
“This powerful, haunting memoir . . . shows in an incredibly intimate way the methods we use to cope with loss, disappointment, and grief, and how we can try and make our way out of the darkness and into a place of recovery.” — Kristin Iversen, NYLON
“She writes vividly of the exposed-nerve pain of losing a parent at such a tumultuous age.” — Andrew Schenker, Los Angeles Review of Books
“ . . . beautiful and complex, but also a great example of what is possible when a very skilled storyteller starts manipulating form in a way that allows her to go deeper into the subject, in part by commenting openly on all the things she might not remember.” — Melissa Oliveira, Hippocampus
“Jeannie Vanasco’s The Glass Eye is the beautiful and multilayered journey of a writer paying tribute to her father, while also discovering herself.” — E. Ce Miller, Bustle
“In this stunning, quite meta memoir, Vanasco attempts to come to terms with many things: Her beloved father's death, the name she shares with a dead half-sister she never met, and her own crescendoing mental illness. All the while, she talks the reader through her obsessive, meticulous writing process as she tries to finish the memoir she promised her dying father she'd write for him.” — Entertainment Weekly
“Excellent memoirs can resonate for various reasons—the singularity of the experience, the artfulness of the prose, the honesty of the voice. Jeannie Vanasco’s book hits for the cycle.” — David Giffels, Literary Hub
“The Glass Eye by Jeannie Vanasco is an evocative and heartbreaking exploration of family bonds, mental illness, and memory.” — Dahlia Balcazar, Bitch
“Her story isn’t always comfortable for the reader, but it is captivating.” — Stephanie Topacio Long, Bustle
“Jeannie Vanasco’s debut memoir is a portrait of a daughter’s grief for her father with a twist: It’s also a wildly innovative tale of the author’s own mental breakdown after his death.” — New York
“This book has a blazing lyricism to it, one that’s bound to be a trademark of Vanasco’s limber mind. . . . The Glass Eye—spare, deep, and kaleidoscopic—will make you want to read the first page again after you finish the last.” — Amy Jo Burns, Ploughshares
“Vanasco explores the intricacies of the human psyche with stunning poignancy.” — Newsweek
“Vanasco’s memoir is valuable reading for anyone who has ever tried to create something. Artists of all stripes will see that it is, in fact, Vanasco’s tireless self-awareness of her own role (as memoirist, as careful practitioner of her craft) that allows The Glass Eye to function as a fruitful addition to the genre.” — The Arkansas International
“The form is a beautiful, effective illumination of Vanasco’s process in working through her grief and mental illness, but also in constructing the book. . . . it invites the reader in to examine, with Vanasco, the nuances of life as a human being searching for meaning, for connections to the people we love, and the moments that stay with us, for whatever reason, long after they’ve passed into memory.” — Rachel Wooley, Atticus Review
“Unpacking the meanings of her name, her identity, and how to live without her father makes for a fascinating, poignant story that will speak to many readers.” — Lorraine Berry, Signature
“Vanasco writes movingly about mourning for a beloved parent, bipolar disorder and searching for the dead sister she never knew — who non-coincidentally shared her name.” —Baltimore Sun
“Her memoir reads like a documentary unfolding in the mind’s eye, a camera pointing at the subsections of her life—Dad, Mom, mental illness, death, life, love—to craft a complete story of grief and loss.” — Nada Sewidan, Vanguard
“Jeannie Vanasco’s The Glass Eye [is] a remarkable and peculiar memoir/meta-memoir. ... Vanasco uses her preoccupation with metaphor and with deciphering meaning to bring her readers into a mind in chaos.” — Emery Ross, The Seattle Review of Books
“There’s a bit of a battle among the staff at the Women & Children First Bookstore: They can’t decide who gets to put Jeannie Vanasco’s memoir The Glass Eye as their staff pick—too many of them want to recommend it.” — Tracy Mumford, Minnesota Public Radio
“Wise, brave, and beautifully wrought, The Glass Eye signals the arrival of an exceptionally fine new voice.” — Alexandra Styron, author of Reading My Father
“Jeannie Vanasco’s The Glass Eye is memoir as it ought to be, but so rarely is: beautiful and painfully raw, but also restrained and lyrical. Vanasco is brilliant, and this book proves it.” — Darin Strauss, author of Half a Life
“In The Glass Eye, Jeannie Vanasco shows us why rules should be broken: because an elegy that pulses with immediacy, a fragment that is inextricable from a whole, a book that comments on its own writing can smash what you think you know into pieces, and expose a piece of truth so bright it might be your own broken heart, handed back to you.” — Melissa Febos, author of Abandon Me
“In The Glass Eye, the writer asks, in prose that mesmerizes with geometric precision, how we can orient ourselves to the world when our only compass is grief. What begins as an experience of profound loss becomes an obsession, the fierce intensity of which propels readers through this breathtaking book.” — Lacy Johnson, author of The Other Side
“With The Glass Eye, Jeannie Vanasco has produced a debut of incisive vision. In prose as vivid as a novel and as chiseled as poetry, Vanasco shows the reader that memoir can entail an unexpected, ultimately liberating reckoning.” — John Keene, author of Counternarratives
“I loved every word of The Glass Eye. It’s a story about stories, a story about the impossibility of ever telling the whole story. It’s a detective story that interprets itself as it goes, raising the stakes and thickening the plot. It’s also a love story, a ghost story, a story about the most important man who ever lived: the narrator’s dad. Her literal reason for being. But it’s also a story that I can’t help but feel was written just for me.” — Daniel Raeburn, author of Vessels
“The Glass Eye is heartbreaking and harrowing and at times painfully intimate, but it ends on a note of tentative closure: Vanasco has found a loving partner, moved to the Baltimore area to teach writing, and fulfilled her promise to her father, splendidly.” — Kelsey Osgood, author of How to Disappear Completely
“This heartbreaking memoir is so smart, so tightly constructed, and so moving that it broke me—both formally and emotionally.” — Michael Kimball, author of Big Ray
“An absolutely beautiful exploration of family, grief, memory, and madness, this book is outstanding . . . The layers found in this memoir are as plentiful as the layers found in the human eye; ultimately, it is as deeply layered as the human experience itself.” — Jamie Thomas, Women & Children First
“This is memoir at its best. The prose is powerful and often breathtaking—it’ll make your heart break, it might make you cry, and you’ll probably even laugh a few times. This is an elegy fierce and lyrical and raw, like none I’ve read before.” — Sarah Malley, Newtonville Books
“Vanasco has this unique and brilliant way of structuring her narrative that leaves the reader bewildered and enlightened at the same time . . . I am not one for memoirs, but this is a rare gem that highlights something so sacred as a daughter's relationship to her father.” — Jason Kennedy, Boswell Book Company
“The Glass Eye is a literary tour de force, a hurricane of language and emotions that fly off the page, a testament to love and loss and how the lexicon of grief, though universal, is always a personal discourse.” — Rachel Kaplan, Avid Bookshop
“I have never read anything quite like The Glass Eye . . . The writing is fierce and engaging, and I truly couldn't put it down.” — Courtney Flynn, Trident Booksellers & Cafe
“Somewhere between grief and madness lies The Glass Eye―an unfettered dive into a brilliant, unraveling mind. Vanasco's memoir is visceral, poignant, and ultimately an affirmation of the healing power of literature and the resilience of the human soul. Astounding.” — Keaton Patterson, Brazos Bookstore
“Jeannie Vanasco has crafted a book that will worm its way under your skin, a book that will not give you easy answers or heartwarming takeaways, much in the same way that life will not give you easy answers or heartwarming takeaways. Jeannie Vanasco has created a book that I cannot stop thinking about.” — Emily Ballaine, Green Apple Books
“Jeannie is a gifted writer with a unique voice and the story of her family’s mysteries, including her discovery of a dead half-sister with her same name, and, of course, her father’s glass eye, are compelling and haunting. The Glass Eye is reminiscent of other memoirs of grief and madness, but that makes this enchanting book sound darker than it really is. Vanasco's humor and intelligence shine through her journey of loss.” — Sarah Goddin, Quail Ridge Books
“Jeannie Vanasco grew up in the shadow of her dead half-sister, Jeanne. In her deftly written memoir, she examines how this experience, along with her father’s death and a difficult-to-diagnose mental illness, left her haunted and obsessed. You too will be transfixed by Vanasco’s strange, remarkable story.”— Renee P., Powell's Books
“The Glass Eye is absolutely brilliant! ... Jeannie’s ability to express the complexities of the human mind in such a beautiful and honest way made her mania appear almost rational. For me, this memoir transcends beyond a daughter’s love and loss of her cherished father. One of the best memoirs I've read in a long time.” — Stephanie Coleman, Tattered Cover Book Store
“The Glass Eye is a beautifully written memoir about love, loss, grief, and mental illness. . . a book I won’t soon forget.” —Hunter Gillum, Beaverdale Books
“Read this book. It will change you.” — Katherine M., Powell's Books
Available in the UK as My Father's Glass Eye,
it can be purchased in bookstores and online at Foyles, Waterstones, Blackwell's, and Amazon.
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Justia Lawyer Directory Construction Law Pennsylvania Derry Attorneys
Derry, Pennsylvania Construction Lawyers
Brian R. Davidson
Pennsylvania Construction Law Attorney
University of Pittsburgh School of Law3rd Circuit, 5th Circuit, Supreme Court of Pennsylvania and United States District Court for the Western District of Pennsylvania
Pennsylvania Construction Law Lawyer with 11 years experience
Western Michigan University Cooley Law SchoolU.S. District Court for the Middle District of Pennsylvania, U.S. District Court for the Western District of Pennsylvania and Pennsylvania
Denise Hunkele Sullivan
Pennsylvania Construction Law Lawyer
University of Pittsburgh School of Law3rd Circuit, 6th Circuit, Pennsylvania and U.S. District Court, Western District of Pennsylvania
Haig M. Sakoian
University of Pittsburgh School of LawPennsylvania, The United States Court of Appeals for the Third Circuit and The United States District Court for the Western District of Pennsylvania
Elizabeth Tarasi
Pittsburgh, PA Construction Law Attorney with 28 years experience
(412) 391-7135 510 Third Avenue
Free ConsultationConstruction, Energy, Personal Injury and Real Estate
Duquesne University School of Law
I have been helping people with the legal issues and claims for 28 years. Injuries, auto accidents, wrongful death, slips & falls, real estate & property issues, condemnation, legal malpractice, business issues, insurance claims, wills & probate, contract disputes, construction claims, real estate developer issues. I want to help. No issue is to big or too small. Call me first. 412-391-7135. I will answer your call.
Daniel Patrick Lynch
Canonsburg, PA Construction Law Attorney with 27 years experience
(724) 776-8000 375 Southpointe Blvd.
Construction, Business, Real Estate and Securities
Daniel P. Lynch, Founder and Managing Partner of The Lynch Law Group, has been a practicing attorney for more than 26 years. His areas of strength and experience include commercial litigation; securities litigation; employment law counseling and litigation; business succession planning; mergers and acquisitions and general corporate transactions.
Dan is a success-driven leader with superior organization and communication skills. He has practical business experience, a solid work ethic and brings an entrepreneurial approach to his practice of law.
Joseph Leonard Luciana III
Pittsburgh, PA Construction Law Attorney with 7 years experience
(412) 926-1812 20 Stanwix St
Construction, Arbitration & Mediation and Environmental
Erica L. Laughlin
(412) 281-5423 444 Liberty Avenue, Suite 2200
Construction, Medical Malpractice and Personal Injury
University of Pittsburgh School of Law
Erica L. Laughlin, a Shareholder of Strassburger McKenna Gutnick & Gefsky, has a civil litigation practice in state and federal courts. Known for her energy, attention and dedication to her clients and their needs, Ms. Laughlin has successfully represented individuals and businesses in commercial disputes and civil matters, including personal injury, premises liability, professional malpractice, insurance defense, civil rights defense, entertainment and media, construction and municipal law.
Claimed Lawyer ProfileLII SilverSocial Media
James Malloy
Pittsburgh, PA Construction Law Attorney
Construction, Business and Insurance Defense
Ryan D. Very
Pittsburgh, PA Construction Law Lawyer with 5 years experience
(412) 430-0131 500 Grant Street
Construction, Business, Consumer and Foreclosure Defense
Like his late grandfather, Ryan Very is a zealous trial attorney who asserts rights and promotes justice. A fourth-generation Pittsburgher, he has represented hundreds of small businesses and consumers in a wide-variety of civil litigation and criminal defense matters. Mr. Very attended a top-twenty law school. Upon graduation he was awarded a fellowship at the American Civil Liberties Union, one of the most sophisticated legal organizations in American history. He worked at the Pennsylvania chapter, which legalized same-sex marriage state-wide. A proficient litigator, he has negotiated hundreds of thousands of dollars in civil settlements, and plea bargained for the withdrawal...
John R. Dingess
Pittsburgh, PA Construction Law Lawyer
Southwestern University School of Law
Catherine Loeffler
(412) 288-2262 Three Gateway Center
401 Liberty Avenue, 22nd Floor
Construction, Business, Employment and Insurance Defense
I chose a career in law to satisfy my desire to help individuals and businesses in their everyday interactions. I take a results-oriented approach while being mindful of cost-effective solutions and remaining open-minded to non-traditional techniques. I recognize that there is a time for aggressive representation of my clients, and there is a time for negotiation. The client's voice is always heard, and I have the skills and experience necessary to turn my clients' aspirations into success stories.
Ronald J. Chleboski Jr.
The University of Utah S.J. Quinney College of Law
John P. Miller
Jeremy K. Knaebel
Duquesne University School of LawOhio, Pennsylvania, U.S. District Court, Northern District of Ohio and U.S. District Court, Western District of Pennsylvania
Laura M. Hillenbrand
The Ohio State University Michael E. Moritz College of LawVirginia
Victor Abraham Delnore
Pittsburgh, PA Construction Law Lawyer with 10 years experience
Construction, Business and Insurance Claims
The Ohio State University Michael E. Moritz College of Law
Julian Neiser
(412) 325-1116 301 Grant Street, Suite 3440
Free ConsultationConstruction, Arbitration & Mediation and Business
Julian is a member in the Pittsburgh office of Spilman Thomas & Battle, where his practice focuses on commercial litigation, construction disputes, insurance coverage, and intellectual property litigation. He serves as co-chair of Spilman's construction law group In addition to his practice, Julian is an adjunct professor at Duquesne University School of Law where he teaches in the trial advocacy department and coaches several trial moot court teams. Julian is a member of the rules of civil procedure committee and is the chair of the construction law section of the Allegheny County Bar Association. He also is a...
Aubrey T. Smith
Carl J. Spindler
Construction, Arbitration & Mediation and Insurance Claims
University of Minnesota Law School
Stanley Stein
(412) 904-4573 445 Fort Pitt Boulevard
Construction, Business, IP and Patents
Duquesne University School of Law and University of Pittsburgh School of Law
"I've been fortunate to have had the opportunity to practice in areas of law that are fascinating and challenging. More than thirty-eight years of litigating cases involving technology and business innovation means that every case is different and interesting. I am continually learning about technological advancements that I might not otherwise learn about and meeting clients who are super intelligent, entrepreneurial and adventuresome." Spending his entire law career with Feldstein Grinberg Stein & McKee, Stanley Stein concentrates his practice in Business-Related and Commercial Litigation, including Trade Secret, Non-Compete, and Intellectual Property Litigation, including Patent and Trademark Litigation. In addition, he litigates...
Claimed Lawyer ProfileLII Gold
Todd Elliott Esq
(412) 400-5476 425 First Ave
Construction, Divorce, Family and Personal Injury
Todd W. Elliott, Esq. is a Pittsburgh area resident and a litigator by vocation. For 16 years, he practiced civil litigation (plaintiff and defense) throughout Western Pennsylvania. Having worked for two prominent regional firms, Mr. Elliott's areas of practice include breach of contract, construction law, mechanic's liens, invention design cases, contractor/sub-contractor disputes, covenant not-to-compete (non-compete clauses), employee defense of non-compete, business enforcement of non-compete, trade secret violations, theft of mailing lists/recipes, professional negligence, premises liability, unfair trade practices, trade disparagement, and multistate litigation. Over the course of his career, Mr. Elliott handled the mediation of disputes, several trials by jury,...
The University of Utah S.J. Quinney College of Law10th Circuit, Pennsylvania and United States District Court for the Western District of Pennsylvania
Andrew P. Giel
The Pennsylvania State University School of Law
Gina Berardinelli Banai
Bentleyville, PA Construction Law Attorney with 16 years experience
Bentleyville, PA 15314
Construction, Business, Energy and Real Estate
Samantha Brutout
George B. Foster
Kartik N. Subramany
(412) 345-8144 615 Iron City Dr.
Construction, Consumer, Personal Injury and Products Liability
Kartik Subramany is an experienced Pittsburgh, PA personal injury and national table saw injury attorney working at the Chaffin Luhana LLP law firm. He is fully committed to providing each and everyone of his clients with the best possible legal representation. He does this by successfully seeking and recovering the maximum amount of compensation for his injured client's full emotional and or physical recovery. Practice areas include but are not close to being limited too: Personal injury, table saw injury, wrongful death, motorcycle accidents, truck accidents, bicycle accidents, brain injuries, burn injuries, spinal cord injuries, pedestrian...
Mark Francis McKenna
(412) 471-6226 436 Boulevard of the Allies
Construction, Medical Malpractice, Personal Injury and Products Liability
Pittsburgh attorney Mark F. McKenna has over 35 years of trial experience with a concentration in the area of Civil Litigation, including products liability, medical malpractice, nursing home negligence and personal injury litigation.
Arthur Stroyd
(412) 944-2723 3 PPG Place
Construction, Business and Products Liability
Arthur H. Stroyd is a founding partner at the firm Del Sole Cavanaugh Stroyd, LLC, where he and a team of lawyers offer counsel for personal injury, commercial litigation and appellate litigation matters. Mr. Stroyd has been practicing law for over four decades. In his legal career, Attorney Stroyd has assisted countless Pennsylvania residents. He has been recognized as a Martindale-Hubbell® AV Rated® lawyer for the past three decades, and selected for inclusion in the list of Super Lawyers® for the past 11 years. The Best Lawyers in America named him as Lawyer of the Year in 2014. To receive...
Matthew Lautman
(412) 288-5017 Three Gateway Center, 22nd Floor
401 Liberty Avenue
Free ConsultationConstruction, Business, Collections and Personal Injury
Matt is a trial attorney focusing on business, construction, collections, and probate, estate and trust litigation matters. Matt routinely represents his clients in both federal and state court, along with private arbitration and mediation.
As part of his business litigation practice, Matt frequently handles breach of contract claims, tort litigation claims, non-competition/non-solicitation matters, and shareholder disputes. As part of his construction law practice, Matt frequently represents architects and engineers in design defect cases, and assists all his construction clients, including design professionals, contractors, and suppliers in filing, when applicable, mechanic’s lien claims or making claims through the CASPA and...
Dennis Michael Moskal
(412) 926-1702 US Steel Tower
600 Grant Street, Suite 660
Construction, Business, Consumer and Employment
Duquesne University School of Law3rd Circuit, 8th Circuit, Pennsylvania, U.S. Supreme Court, United States Court of Appeals for the District of Columbia, United States District Court for the Eastern District of Pennsylvania, United States District...
University of Minnesota Law SchoolMinnesota and Pennsylvania
Theresa Boland O'Brien
Construction, Business, Personal Injury and Products Liability
Theresa O’Brien has more than 20 years of corporate and civil litigation experience. Theresa is admitted to practice in the States of Ohio, West Virginia and Pennsylvania.
Brian Simmons
Construction, Appeals, Business and Environmental
Charles Gibbons
James Glunt
Construction, Arbitration & Mediation, Business and Real Estate
Lisa Poerio Means
(412) 288-3182 435 Sixth Avenue
Construction, Arbitration & Mediation, Business and Energy
Robert King
Frank McKenna
Arnd von Waldow Esq
Michael Manzo
Duquesne University School of LawPennsylvania
Southwestern University School of Law2nd Circuit, 3rd Circuit, 5th Circuit, Pennsylvania, Supreme Court of Pennsylvania and U.S. District Court for the Western District of Pennsylvania
Use Justia to research and compare Derry attorneys so that you can make an informed decision when you hire your counsel.
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Police: Mom intentionally put 4-year-old in hot car as punishment
By Artemis Moshtaghian and Hollie Silverman, CNN
Salt Lake Co Sheriff's Office
Jesica Brown
SOURCE: Salt Lake Co Sheriff's Office
A Utah woman was arrested last week for putting her child in a hot car with the windows up.Police arrived at Draper Park within five minutes of receiving a call from bystanders about the boy on July 2 at around 9 a.m., Draper Police Lt. Pat Evans said.When they arrived, officers found him in a vehicle that was turned off with the windows up in 82-degree heat, he said.Jesica Brown, 28, told police that she put her 4-year-old son in the car as punishment for misbehaving in the park, Evans said.A probable cause affidavit said an officer on the scene found the child's head was hot to the touch, he was sweating and his eyes were puffy, CNN affiliate KUTV reported.Both Brown and her boyfriend, who was not implicated in the incident, were standing outside the vehicle the entire time the child was inside, Evans told CNN.Police removed the child from the vehicle and found needles in the mother's purse and in the vehicle, KUTV reported.Officers found a used needle in Brown's purse and paraphernalia in her car consistent with heroin use, the news station said.According to the affidavit, the mother admitted to using methamphetamine and heroin to an officer, KUTV reported.Brown was charged with child endangerment because the child had access to drugs or drug paraphernalia, and child abuse for leaving her son in the hot vehicle, Evans said.Evans told CNN the case has been referred to the Salt Lake District Attorney's Office.CNN could not immediately reach Brown for comment on the charges against her.
A Utah woman was arrested last week for putting her child in a hot car with the windows up.
Police arrived at Draper Park within five minutes of receiving a call from bystanders about the boy on July 2 at around 9 a.m., Draper Police Lt. Pat Evans said.
When they arrived, officers found him in a vehicle that was turned off with the windows up in 82-degree heat, he said.
Jesica Brown, 28, told police that she put her 4-year-old son in the car as punishment for misbehaving in the park, Evans said.
A probable cause affidavit said an officer on the scene found the child's head was hot to the touch, he was sweating and his eyes were puffy, CNN affiliate KUTV reported.
Both Brown and her boyfriend, who was not implicated in the incident, were standing outside the vehicle the entire time the child was inside, Evans told CNN.
Police removed the child from the vehicle and found needles in the mother's purse and in the vehicle, KUTV reported.
Officers found a used needle in Brown's purse and paraphernalia in her car consistent with heroin use, the news station said.
According to the affidavit, the mother admitted to using methamphetamine and heroin to an officer, KUTV reported.
Brown was charged with child endangerment because the child had access to drugs or drug paraphernalia, and child abuse for leaving her son in the hot vehicle, Evans said.
Evans told CNN the case has been referred to the Salt Lake District Attorney's Office.
CNN could not immediately reach Brown for comment on the charges against her.
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Ernst: You should've taken me seriously
Dec 6, 2019 - 06:49 pm By Nkululeko Dladla
League-leading coach Ernst Middendorp has reminded people how he was laughed at when he spoke about Kaizer Chiefs' intentions at the start of the season.
Amakhosi since then have been unstoppable and now sit with a 10-point lead at the top of the Absa Premiership log and it seems like no one can stop their moving train as they keep extending the gap.
Middendorp building up to their match against Bloemfontein Celtic on Saturday (20h15) said he remembered how people received his comments when when he spoke about their ambitions for this campaign, and now they are proving it.
READ: Bobby urged to visit transfer market
"The process was very clear, we started in July presenting our ideas, having targets and goals of being in the competition for the championship," he said.
"In the Absa building at the beginning of this season, I've said several times, not only doubting. There were a lot of smiles around the corner, you could recognise.
"At the moment we only have turned it into the direction to say 'okay, what was said in August on the opening day of the league, probably we should've taken this guy seriously'. What was said is now a period to show we are in the competition."
READ: Agent: My player would join Chiefs
The German coach knows his team should not become too comfortable and keep the same attitude they have had throughout the season.
"This is December time. Of course [we are] feeling comfortable on one side but feeling comfortable should not be our main target, and definitely you can be sure about our preparations so we can provide an even better position [going forward]."
READ: Middendorp opens up on Billiat problem
READ: Manyama identifies Celtic's two threats
PHOTOS: Focused: Naturena all Black and Gold
How to watch Wydad vs Sundowns
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King & Bay
Alderon Iron Ore Corp.
Canada Jetlines Ltd.
Excelsior Mining Corp.
Lithion Energy Corp.
Voleo Inc.
Xineoh
WE TAKE COMPANIES
From INNOVAtION to excellence
With an eye to the latest trends and leveraging the vision of our founder, we have become the experts in panning through the rubble of risk to extract the gold of opportunity.
Growing & Investing in Promising Business Ventures
King & Bay is a merchant bank that specializes in identifying, funding, developing and managing resource and technology business opportunities. We take a holistic approach to working with our clients to emphasize the direct link between the end product, company management, the board of directors and, ultimately, the shareholder, which allows us to build long-term shareholder value.
At King & Bay we are continuously reaching new levels of growth and achievements. Follow our social channels to stay up to date with the latest news.
Voleo Trades on OTCQB And Announces Top Colleges Participating in Equity Trading Competition Sponsored by Nasdaq
Voleo Trading Systems Inc. (TRAD: TSX-V, VLEOF: OTC-QB) (“Voleo”, the[…]
Excelsior Mining Announces Positive Initial Wellfield Results at the Gunnison Copper Project
Phoenix, Arizona--(Newsfile Corp. - January 8, 2020) - Excelsior Mining[…]
Excelsior Mining Commences Mining Operations at the Gunnison Copper Project
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Subscribe today to stay up to date on the latest news from our companies
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Independent research and analysis on health and social care
Viewing: All publications
Evidence and consultations
(-) Cancer services
(-) Public health
(-) Patient involvement
Creating healthy places: perspectives from NHS England’s Healthy New Towns programme
Creating healthy places: perspectives from NHS England’s Healthy New Towns programme provides personal insights from those involved in the programme, illustrating how powerful a coherent local approach to improving population health can be.
By Chris Naylor - 26 September 2019
The NHS long-term plan explained
On 7 January, the NHS long-term plan was published setting out key ambitions for the service over the next 10 years. In this explainer, we set out the main commitments in the plan and provide our view of what they might mean, highlighting the opportunities and challenges for the health and care system as it moves to put the plan into practice.
By Anna Charles et al - 23 January 2019
A vision for population health: Towards a healthier future
We need to move away from a system just focused on diagnosing and treating illness towards one that is based on promoting wellbeing and preventing ill health. Our report sets out a new vision for population health.
By David Buck et al - 27 November 2018
Shared responsibility for health: the cultural change we need
We believe that the relationship between the public and the NHS, and between patients and the staff who care for them, needs to be transformed. As well as ensuring that the resources (funding and workforce) needed to deliver care are available, national and local leaders must work to fully engage patients and the public in improving health and care.
By Professor Sir Chris Ham et al - 23 November 2018
The English local government public health reforms: an independent assessment
This report, commissioned by the Local Government Association, assesses the success of the 2013 reforms to public health in England, which were part of the Coalition government’s wider health reform programme.
By David Buck - 13 January 2020
Evidence and consultation
Implementing the NHS long-term plan: written submission to the House of Commons Health and Social Care Select Committee
Successful implementation of the NHS long-term plan depends on adequate funding for social care and public health, NHS education and training, and capital investment.
What is happening to life expectancy in the UK?
2011 marked a turning point in long-term mortality trends in the UK, with improvements tailing off after decades of steady decline. Veena Raleigh examines the data.
By Veena Raleigh - 22 October 2019
Advancing our health: prevention in the 2020s consultation
Our response to the government's consultation paper on prevention focuses on the additional areas we would like future government policy to cover.
Clicks and mortar: Technology and the NHS estate
Financial pressures and growing demand mean that health and social care services will need to work differently. This report reviews how technology in the NHS estate is currently being used, and imagines how the 'estate of the future' might look.
By Lillie Wenzel et al - 21 May 2019
NHS long-term plan: legislative proposals inquiry: Written submission to the Health and Social Care Committee
Our response to the Health and Social Care Committee's legislative proposals inquiry. We support the spirit of these proposals, which are intended to make it easier for local NHS bodies to work together to improve the health and care of their populations.
Sexual health inquiry: Written submission to the Health and Social Care Committee
Funding cuts to England's sexual health service are having an impact on provision. Against this background, the Health and Social Care select Committee’s inquiry is extremely timely, and we welcome the opportunity to contribute to this.
Stalling life expectancy in the UK
The stalling of improvements in life expectancy in the UK since 2011, highlighted again in the most recent data, has prompted much comment and speculation. We must look at austerity and beyond for underlying causes, says Veena Raleigh.
By Veena Raleigh - 28 September 2018
Joined-up listening: integrated care and patient insight
In this article, we articulate the opportunity that integrated care presents for using insight from people and populations to design services that meet their needs and reflect their priorities.
By Dan Wellings et al - 30 August 2018
The Montefiore Health System in New York: a case study
The Montefiore Health System in the Bronx, New York, has found ways of helping even the most deprived by stepping beyond the bounds of conventional health services. Our report explores the system in detail.
By Ben Collins - 27 July 2018
It’s time for a new deal between the public and the NHS
The 70th anniversary of the NHS is an opportunity to reflect on its enduring popularity and to ask what people can expect from the service and what their obligations are in return, says Chris Ham.
By Professor Sir Chris Ham - 5 July 2018
A new deal with the public
It’s time to revisit what people can expect from the NHS and what their obligations are in return, writes Chris Ham.
By Professor Sir Chris Ham - 25 June 2018
The role of cities in improving population health: international insights
Drawing on international case studies, this report explores the role of cities in improving population health and the conditions needed for success.
By Chris Naylor et al - 15 June 2018
The Montefiore Health System in New York: integrated care and the fight for social justice
The Montefiore Health System in the Bronx, New York, has found ways of helping even the most deprived by stepping beyond the bounds of conventional health services.
By Ben Collins - 25 April 2018
Local authority public health prescribed activity call for evidence: The King's Fund response
David Buck responds on behalf of The King's Fund to the Department of Health and Social Care's local authority public health prescribed activity call for evidence.
By David Buck - 17 April 2018
Tackling multiple unhealthy risk factors: emerging lessons from practice
Our report shares learning and insight from services that are using innovative ways to address the problem of multiple unhealthy behaviours – around tobacco use, alcohol consumption, diet and physical activity – in the population.
By Harry Evans et al - 1 March 2018
Communities and health
The role of communities in improving population health is receiving increasing, and long overdue, attention in health policy and practice. This piece gives an overview of the different approaches to working with communities for health.
By David Buck et al - 14 February 2018
The King’s Fund response to the Mayor of London’s draft health inequalities strategy
We find that the draft strategy is a good start, but we believe as it is finalised its commitments need to be more tightly focused on inequality reduction than they currently are.
Patient involvement: Paul’s story
Paul Radin speaks to us about his experience of patient involvement at The King’s Fund.
By Paul Radin - 30 November 2017
What is happening to waiting times in the NHS?
We examine the big issues and recent NHS performance on waiting times.
By Siva Anandaciva et al - 8 November 2017
Health and care explained: How does the health and care system work? How is it changing?
This selection of content aims to make sense of the health and care system – including videos, articles, illustrated summaries and more.
Got a question? Ask a librarian
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CREDIT: LONDON ARRAY LIMITED
The London Array is the largest operational offshore wind farm in the world. Each of its 175 turbines has blades that measure 120 meters in diameter. Together, the turbines have the capacity to generate 630 megawatts of power.
Bumpy air boosts wind power
Turbulence regenerates gust strength between turbines, influencing design of arrays that can pull energy from the sky
By Ashley Yeager 11.30.2017
From far above the Earth, the London Array looks like rows of perfectly aligned ships sailing toward England’s eastern coast, preparing for a fight. But there’s no need to tilt at these wind turbines, as Don Quixote might. The array is not a monstrous threat — it’s the world’s largest operational offshore wind farm. With 175 turbines covering 100 square kilometers, the array currently provides enough power for about 500,000 United Kingdom homes.
“The London Array has quite an impressive number of turbines. But some of the wind farms on the horizon will be double the size,” says wind energy expert Gregor Giebel of Technical University of Denmark. To ensure the future farms’ success, researchers need a good grasp of how air twists and turns around each turbine, how it flows through the entire farm and even how one wind farm affects another one sitting, well, downwind.
From far above the Earth, the London Array, a wind farm off the coast of England, looks like rows of ships ready to attack. In reality, the turbines provide power for hundreds of thousands of homes in the United Kingdom.
CREDIT: JESSE ALLEN AND ROBERT SIMMON; LANDSAT 8 – OLI/NASA EARTH OBSERVATORY
“Wind energy is coming along very nicely and growing very rapidly,” says Johns Hopkins University engineer Charles Meneveau, who studies the fluid mechanics of wind farms. Right now, land-based wind energy is the least costly form of electricity (if you don’t count subsidies) — less expensive than gas, coal or nuclear power. “People don’t realize this, but it is the cheapest,” Meneveau says. “So that is why one can expect many more wind farms to be built in the next decade.” Offshore wind farms will be a part of that development, too.
Currently, offshore arrays are more expensive to build than land-based ones. But as turbines and arrays grow larger to harvest more energy, Giebel says, moving out to sea may be the best bet to harvest maximum power and avoid issues with construction on land.
Detailed simulations built on supercomputers shows the flow of air in a very large wind farm. The blue regions represent the wakes, low-velocity wind-speed regions, formed behind the turbines. The white streaks represent individual particles, which show how air moves through the array at very different speeds. Such simulations help scientists understand how turbulence acts within turbine arrays and can guide design for more efficient energy generation.
CREDIT: DAVID BOCK/NCSA AND XSEDE; COURTESY OF RICHARD J.A.M. STEVENS
Whether on land or at sea, detailing the intricacies of airflow is essential to extracting maximum electricity from future wind farms. To determine how much power next-gen farms can produce, Meneveau and his colleagues are developing detailed computer simulations of the way air moves through large turbine arrays. In the 2017 Annual Review of Fluid Mechanics, Meneveau and physicist Richard J.A.M. Stevens of the University of Twente in the Netherlands describe the physics of airflow in a wind farm, the way that flow interacts with layers of air above it, and how chaotic changes in airflow actually boost a wind farm’s power output.
By the end of 2016, wind power accounted for an estimated 4 percent of the world's renewable-energy production of electricity.
Unsteady air
Ideally, the most efficient wind farm would situate turbines far apart. But in the real world, real estate for wind farms is limited. So turbines are usually built in denser arrays. The London Array’s 175 turbines, for example, are arranged in a matrix.
Arranging the turbines in a matrix has its problems. The wind loses energy as it moves from one row of turbines to the next. Once past the first row, the oncoming wind forms what’s called a wake, which typically carries only about 50 percent of the wind’s initial strength. Each turbine row the wind encounters will slow the breeze down until, theoretically at least, there should be very little energy from the initial gust left to harvest. Yet wind farm arrays with 20 or even 40 rows of turbines generate energy throughout the array.
Turbulence, Meneveau says, provides the needed boost.
Mere mortals tend not to like turbulence; it’s what jostles you around on a plane at 30,000 feet, leaving you with a slightly queasy feeling. Turbulence, however, is exactly what helps wind turbines extract maximum power from the air. Turbulence is generated when layers of air don’t flow in parallel lines; instead, differences in pressure lead to faster flow velocity, which rough up the air, creating swirls and eddies.
Turbulence in the air above a wind farm stirs energy into the wake behind a turbine, Meneveau and his colleagues’ simulations have shown. Crunching the data from real wind farms plus studying simulations shows that with turbulence, the last rows of turbines can produce just as much power as turbines in the second, third and fourth rows.
Wind farms arranged in rows should, theoretically, lose power as more and more turbines are added: Wakes grow, leaving less wind energy to pass on to turbines in the later rows. However, turbulence from the layer of air above the turbines and from within the wakes can add energy back into the flow, allowing for the turbines in the later rows to generate just as much power as those toward the front.
SOURCE: Adapted from R.J.A.M. Stevens and C. Meneveau/ Annu. Rev. Fluid Mech. 2017
CREDIT: D. BECKNER/KNOWABLE MAGAZINE
But for turbulence to help harvest wind energy, the rows of turbines do have to be placed far enough apart for the wake to have a chance to mix with any rough air. Scientists talk about the distance between rows in terms of rotor diameter, the length of a turbine’s blades. Today’s turbines typically have a rotor diameter of 70 to 120 meters. To maximize the power output and keep the rotors close enough to accommodate space limitations, calculations show, the optimal distance between turbines is about seven times a turbine’s rotor diameter: 500 to 850 meters. But as wind turbines and farms grow larger, Meneveau and a colleague reported in 2012, the optimal distance between turbines could increase to at least 12 times the diameter of a turbine blade — 850 to 1,500 meters. At that distance, the turbines should be far enough apart for turbulence to help the turbines’ wake recover substantially before hitting the next row in the array.
But those calculations don’t provide the final say on the distance between turbines. “You need both the cost of the land and the turbine; only then can you decide where the sweet spot is,” Meneveau says.
For instance, if the land is free and plentiful and there are no electric line costs, then you could put turbines 100 kilometers apart. Each turbine gets fresh wind and is maximally efficient. But if the turbines are free and you pay a lot for the land, then you might put a turbine every three meters. The type of land is also important: the smoother, the better. Forests, ditches, houses and vegetation break down the power of the wind, weakening it before it reaches the first row of turbines. Oklahoma and West Texas are natural locales for building large, well-spaced wind farms. Other types of topographies may call for different approaches to wind energy.
Moving offshore
Offshore wind farms are a good alternative, Giebel argues. The terrain is smooth, with few, if any, obstacles to weaken the wind before it reaches the turbines. There is less turbulence than on land to rebuild the wind strength between turbines, but there is more space to spread the array out.
Also, Giebel says, there are roadblocks, literally, in the logistics of building large-scale onshore wind farms. The turbine blades, towers and other parts are getting so big that trucks run into trouble moving them around corners and under bridges. Offshore construction may be difficult, but there are no size limits. Barges can transport rotors hundreds of meters across and towers 200 to 300 meters tall directly to offshore pads where they’ll be placed.
A single turbine blade can span dozens of meters, making transportation tricky. Trucks must bring them piece by piece to their final destination.
CREDIT: PAUL ANDERSON/WIKIMEDIA COMMONS
The bigger, the better. The seafloor foundations for each turbine are hugely expensive. If the turbines get larger while construction, operations and maintenance costs stay the same, the “cheaper the energy out of the same patch of ocean,” Giebel says.
But researchers don’t yet know if there is a limit to how big they can go with wind turbines and arrays. Questions remain about whether to arrange turbines in a square, an arc or a fan shape to extract the most energy, as well as whether to align the turbines in rows or stagger them. The shape of the wind farm array depends on local conditions at a given site. No general recipes can be stated with confidence, Meneveau says. Specific wind farms must be designed for specific conditions.
Staggering the turbines so they aren’t in perfect rows, however, can increase power production, as suggested by the work of Meneveau, Stevens and others. Meanwhile, Giebel and colleagues have been focusing on the arrangement of turbines and blades, looking to see if there is a way to let just a little bit more energy from the wind slip through each turbine, giving deeper rows slightly more forceful wakes from which to extract energy and maximizing the overall amount generated from each farm.
Along with where to place wind farms, researchers have been studying different turbine arrangements — square, arc and fan, illustrated above. Most large arrays today take the shape of a square. But each location is different. For example, off the coast of Copenhagen is Middelgrunden, a 20-turbine array built in 2000 and arranged on a slight curve to mirror historic fortifications of the city. A recent analysis suggests a more optimal layout might be turbines aligned in a fan or heart shape. Deciding on any specific arrangement depends on local conditions at each site, such as prevailing wind directions, land costs and other factors.
Continued research is the only way to anticipate what’s to come, Meneveau says. Wind farm development, he explains, is a lot like the construction of interstate highways decades ago. “In the beginning, no one would have imagined we would have a huge amount of highways crisscrossing the country,” he says. “Whenever we are at a major change in infrastructure, it is sometimes hard to visualize what’s going to happen, so it is crucial that we understand as much as possible about the effects and cross-effects that one might expect from the build-out of wind farms.”
Such arrays have the potential to power all human civilization if built across the oceans, studies suggest. Still, there may be unforeseen environmental effects of large-scale wind farms, such as changes to air moisture and weather. There are also effects on wildlife — both bad (harm to birds and bats) and good (new ecosystems for marine animals like mussels). And any move toward renewable energy creates its own political and economic wake, Meneveau says. Producing wind power on a global scale is probably in for a bumpy ride.
Ashley Yeager is a freelance writer living in North Carolina who moves on foot.
Annual Review of Fluid Mechanics
Flow Structure and Turbulence in Wind Farms
Wind farms are growing not only in popularity but also in size, forcing physicists, engineers and other scientists to work out their complex fluid dynamics, Richard J.A.M. Stevens and Charles Meneveau explain in this article.
Particles get a move on without motors
Plant, reap, repeat — and now rethink
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TOP > Education > Graduate Schools > School of Manga (Master’s Program and Doctorate [Ph.D.] Program) > Diploma Policy
Diploma Policy
Knowledge, Understanding
Possessing knowledge of manga research in Japan and abroad, and analytical ability, as well as being able to express this through skills in Japanese language and IT.
Thinking, Judgement
Constantly furthering the academic investigation of artistic expression, culture and society from the perspective of manga, and having the capability to communicate these results to other countries and other fields.
Skills, Expression
Setting research issues in a structure relevant to current research conditions for manga and its culture, and presenting grounded research results that are of practical use in other fields.
Interest, Motivation
In conjunction with maintaining respect for scholarly research and a motivation to present the latest topics of discussion, conducting the necessary independent learning for that.
Valuing on the dialog between readers and practitioners, and promoting and furthering the broad social interaction surrounding manga culture.
Concurrently applying knowledge of international manga and its environment to production work, and also possessing skills in Japanese language and IT for presenting creative work.
Integrating knowledge of manga from the joint perspectives of the practical and theoretical, broadening your own vision through interaction with writers from other fields and countries.
Based on advanced skills and imagination, creating works contributing to a manga culture that is continually changing through globalization and informatization.
In conjunction with an artistic ambition and imagination beyond the framework of existing manga’s means of expression, always aiming for further development.
While respecting the need for teamwork, demonstrating an attitude of proactive contribution to global manga culture from an international perspective.
Research Staff & Tutors (in Japanese)
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InvestigateWest (https://www.invw.org/2009/06/30/windpower-for-60000-homes/)
Western Exposure
Windpower for 60,000 Homes
By Rita Hibbard, Co-Founder | June 30, 2009
More on Western Exposure
Subscribe to Western Exposure
An Idaho firm is beginning construction of 14 wind parks across southern Idaho that will produce 228 megawatts of electricity and put Idaho in the top 20 states for wind power, the Idaho Statesman reports today. The Exergy Development Group will produce enough electricity to power about 60,000 homes. http://bit.ly/nnpnh
Rita Hibbard
More by Rita
Expanding access to oral health through innovation
A philosophical question: How much medical training is needed to treat patients? Some say it’s the full course as proscribed by existing medical, nursing or dental schools. But when the shortages of doctors, nurses and dentists are ginormous, does the need require a different answer?Consider oral health. “Shortages of dental practitioners and affordable dental care are hurting the health of millions of Americans, many of whom live with pain, miss school or work, and, in extreme cases, face life-threatening medical emergencies that result from dental infections. The situation is particularly severe for poor children and families and in communities of color,” writes Burton L. Edelstein, DDS, MPH Columbia University and Children’s Dental Health Project in a Dec. 2009 report for the W.W. Kellogg Foundation.And, like most health issues, the data shows that Indian Country is at the low end of the spectrum. One study described it this way: “The American Indian / Alaska Native “population has the highest tooth decay rate of anypopulation cohort in the United States: 5 times the US averagefor children 2–4 years of age. Seventy-nine percent ofAIAN children, aged 2–5 years, have tooth decay, with60% of these children having severe early childhood caries (babybottle tooth decay). Eighty-seven percent of these children,aged 6–14 years, have a history of decay—twice therate of dental caries experienced by the general population.”
Measuring the progress in Native American health
Has the Indian Health Service been an effective, government-run delivery system?Consider this from a White House memo: “While there has been improvements in health status of Indians in the past 15 years, a loss of momentum can further slow the already sluggish rate of approach to parity. Increased momentum in health delivery and sanitation as insured by this bill speed the rate of closing the existing gap in age at death.”In other words progress is slow. But Dr. Ted Marrs wrote the memo on April 26, 1976, and the subject was about the original Indian Health Care Improvement Act. “In 1974 the average age at death of Indians and Alaskan natives was 48.3. For white U.S. citizens the average age of death was 72.3. For others, the average age was 62.7.”Dr. Marrs wrote that the “bottom line” was an unavoidable connection between “equity and morality” when there is a more than twenty year differential in age at death between Indians and non-Indians.So what do the numbers look like now?The most recent Indian Health Service data on general mortality statistics is about a decade old now. But it showed that the twenty-year differential has been reduced to a difference of less than five years. “The American Indian Alaska Native life expectancy at birth (both sexes) for the IHS service area population was 72.3 years,” according to the recent IHS report:“Regional Differences in Indian Health, 2002-2003 edition.” Compare that with the average life expectancy for all U.S. races, 76.9 years.
Detroit’s geography of despair includes many seeds of hope
DETROIT – It’s hard to communicate the failure of public policy in this great American city (especially in a few hundred words). A drive around town highlights the consequences from decades of neglect: Abandoned and burned out homes, office buildings as ruins (and dangerous playgrounds), near-permanent unemployment, and thousands of empty lots capped with mounds. These mounds are burial sites of sorts because when a building was destroyed the rubble was left in a pile until time and grass shaped each into a small hill.Yet the geography of despair includes many seeds of hope. One east side neighborhood is transformed by inspiring folk art that brings humor and zest to several city blocks through The Heidelberg Project. Or there is the Community Health Awareness Group’s efforts to exchange needles so that drug users on the streets won’t as easily share disease. The program resulted in a drop of HIV infections from drug users from 33 percent to 17 percent. (And that, too, is the paradox because while an exchange is effective, it’s also difficult to fund). Then there’s the Earthworks Urban Farm. Detroit is a city without large chain grocery stores – only discount stores and “party stores,” or neighborhood enterprises that sell more liquor than protein. Access to fresh fruit and vegetables is a regular barrier for a family trying to eat healthier. But at Earthworks more people – at least in this one neighborhood – are growing their own access to healthy foods.
A Path to College for Kids with Autism
'Stumptown' Is Spreading; who’ll save trees?
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KAPUHUNA·WEDNESDAY, JULY 3, 2019
MSC SHAUN THOMAS VILLAFANA
Whales From Russian “Whale Prison” LET FREE!
you grew up watching the classic film “Free Willy”,
then you can appreciate the awesome news we have to tell you ~
-‘though it does come with a history lesson of events for those who had no idea of what’s been happening at all.
Whaling Ships – Pixabay
“Whaling”, can you believe it’s even a term? For centuries mankind has hunted whales.
Whaling “was practiced as an organized industry as early as 875 AD.” – (according to wikipedia), By the late 1930s more than 50,000 whales were killed annually.
Amazingly Commercial Whaling has never stopped.
Yes some countries have banned it, and lets not get lost in the details, (but if you do wish to learn more of the details the Wikipedia page is constantly updated.)
In Men and Whales, Richard Ellis wrote of how whaling used to be considered admirable. –
“…only through the lens of hindsight that the whaleman’s job becomes malicious or cruel. . .Oil was needed for light and lubrication; baleen was needed for skirt hoops and corset stays. That whales had to die to provide these things is a fact of seventeenth-, eighteenth-, and nineteenth-century life. . .“
Interestingly, although we need Whales for nothing in our practical way of life today, they are still hunted.
-In this case – wanted alive.
Whales are caught for a intercontinental slave trade of one of the most self aware and social beings on the planet.
(~ if not THE most).
It was discovered – thanks to the technology of remote controlled drones– that shoreline “fishing” companies in Russian had been capturing Whales alive – in order to sell to Chinese “renters” for public amusement in aquariums.
According to The Telegraph, these marine parks will pay upwards of $6 million for a whale.
Due to the nature of the trade, and that they were licensed under “renting” over timed incarceration of these noble sentient being’s lives, commercial whaling to-catch-alive for slavery is completely legal through a slip in the cracks of the law for Russia ~ and Russian officials were at a loss for what to do about it.
A Chained and Caged Orca Whale, sad and crying, wondering why the land mammals are doing this to her.
(blog.therainforestsite.greatergood.com/gfl-100-trapped-whales)
Thankfully,
Russian officials had class and a sense of decency – showing humility by calling out for help and asking other nations for assistance in how to solve this issue.
Well we are proud and happy to bring you great news of the release and freedom of the whales!
https://www.youtube.com/watch?v=4911HX4O0QE&feature=youtu.be
https://youtu.be/-3faA9v5sR8
Thank you for tuning into this update!
Much more to come.
Get access to Premium Features for FREE for a year!
‘Whale prison’ discovered by drone in Far East Russia pic.twitter.com/gkZBVmYwVp
— RT (@RT_com) November 8, 2018
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A Brand New Short Read from Jenna Elizabeth Johnson!
Hello Readers! It's been a long time since I posted anything new, but I hope this will brighten up our day. I entered this short tale into a writing competition, but alas, it did not win. Good news is I can now share it with you. My goal is to eventually write a collection of faerie tales set in the Otherworld and starring new characters from Eile. Soot and Stone (featured in the Once Upon A Kiss anthology) is one of those faerie tales and The Curse of Inis Seacht is another. Now, without further ado, here is your faerie tale! Happy reading!
- J.E. Johnson
Once a year, Aneira's village is visited by the Collector, a man tasked with gathering an annual tithe from the people of Inis Seisear. Always hidden beneath a heavy, hooded cloak, it is common knowledge that this unwelcome stranger hides a hideous visage. Not that it matters to Aneira. She is blind, and despite the unquestionable love of her parents, she is tired of their overprotective ways. When her family's tithe goes missing, she volunteers herself as payment instead, unsure of who this Collector really is or if he is as kind as his unusual glamour suggests. What Aneira discovers on the island of Inis Seacht, however, is more than her chance at freedom, but a terrible curse she may or may not have the power to break.
THE CURSE OF INIS SEACHT
A Fae Tale of Eile
by Jenna Elizabeth Johnson
Aneira stood her ground as the rest of the villagers scattered like mice disturbed from their nests. It was mid-afternoon on Samhain, and that evening they would light the great bonfire at the stone circle and offer up their thanks for a bountiful harvest. But not before the tithe was paid to the creature who had come to collect his goods. Just as he’d done every year before, the Collector had arrived at sunset, crossing the dark waters of Lake Ohll in his sturdy boat to demand payment from the poor villagers. Aneira had never feared him, even as a girl, even when the cloak he wore covered his entire body, face and all, sending all the other girls into fits of hysteria as they imagined what gruesome visage might lie beneath that hood. She did not fear him, perhaps, because she had never feared anything. Even when her eyesight began to fade away at the age of five, and even when her own glamour did not begin to manifest until two years ago.
Aneira’s glamour was different than that of her peers, being both a gift and a curse. Although her blindness caused her to walk in a constant fog, her natural Faelorehn glamour offered her a different perspective of her world. In her mind, people, animals, plants and even objects appeared as blossoms of glorious color in her head. And the kinder of heart, the more pure of spirit the person or being, the brighter their aura appeared to her. So, perhaps that was the true reason behind her lack of horror regarding the Collector. This creature, this mangled and disfigured stranger who was feared by all, had the brightest essence she had ever seen in a living thing. Despite his outward appearance, and his harsh words, true goodness burned within.
It was Aneira’s father who stepped forth when it was their turn to pay the tithe.
“P-please, sir. We had a wealth of honey set aside for you, collected from our own hives, but this morning when I went to gather the jars to bring into town ...”
His voice trailed off, his throat closing around the words.
“They were gone, sir,” Aneira’s mother cried. “We searched everywhere.”
The Collector growled in response, “All must give payment. No exceptions.”
The crowd passed around hushed exclamations, backing away from this creature. They had paid their tithes and only remained to see what became of Aneira’s family.
Aneira squared her shoulders and stepped forward.
“You must take me, as payment. I am my parents’ only child, truly more valuable to them than any trinket or harvested crop. We cannot afford to give you any of our extra stores in place of the honey, or my family will go hungry come the winter.”
The young woman’s voice trembled as she spoke, but she refused to back down. She sensed the man standing before her, tall, strong, oozing menace. But that part of her mind that could see into the hearts of others painted an entirely different picture. A soul as brilliant as the sun, as multicolored as a spring day in Eile, radiated past all the layers of darkness and menace.
“Very well,” the man replied. “My boat awaits on the shore. Let us leave before true dark sets in.”
Aneira’s mother rushed forth. “No! Aneira! You mustn’t go with him!”
“I will not allow it!” her father added, anger and disbelief tainting his voice.
Aneira turned to them and clasped their hands. “I must. The creature says we must pay a price, and we have no other thing of value to offer.”
Before her parents could protest any further, Aneira broke free of their hold and hurried after the Collector, his brilliant soul a guiding light along the dark road.
“What is your name?” Aneira dared to ask from her corner of the boat.
They had reached the dock ten minutes after leaving the village square, the Collector climbing in and waiting for her to join him. Aneira, although feeling a little nervous, carefully navigated her way into the unsteady structure before finding her seat. Now, they were on their way to his island, or so she presumed, and the silence between them was more awkward than she liked. Only the lap of the water against the boat’s sides and the breathy gust of wind greeted her ears.
“Quinlan,” the man finally said. “My name is Quinlan.”
Aneira tried the name out on her tongue. She liked it.
“I am Aneira,” she replied with a smile, her eyes narrowing as she attempted to bring the stranger’s form into view. Sometimes, if she tried hard enough, she could make out the physical shapes of people and things with her eyes. Ah, and there he was. A dark blur of cold solitude. Like a storm cloud brewing over the lake. Before Aneira could think of any other questions, the boat came to an abrupt stop, nearly unseating her.
“Your island was the last one I visited,” Quinlan said, standing and stepping out of the boat. “It is the smallest, besides my own. Now, what can you do to earn your keep here?”
Aneira made to stand and almost fell into the water. If not for Quinlan’s quick reflexes, she would have.
“Be careful,” he snapped, his voice low and gruff.
Aneira felt herself being jerked forward and she let out a small yelp of protest before her feet crunched against the gravel below. Icy water lapped at her boots and the hem of her skirts, but before she could grumble a complaint, Quinlan was pulling her forward, his movements jerky and rough.
“You’re hurting me!” she hissed, yanking her arm free. “Have you no manners?”
“No, I do not. I would think, having lived in the island chain all your life, you would’ve caught on to this fact long before now,” Quinlan replied bitterly.
Aneira glared toward the bright source of light taking up all the space in her foggy mind. What in Eile made this man’s spirit shine so brightly?
“Perhaps that is what I can provide for you. Lessons on how to behave in a civil manner. You clearly lack in that area,” she quipped, unafraid of what ire she might be calling down upon herself.
Quinlan merely snarled and took her arm again. Aneira made to resist, but his grip was gentle now, and he didn’t drag her along, only guided her. They walked for about a mile, leaving behind the shoreline and finding sturdier ground.
Aneira drew in a deep breath and let it out slowly. “Would you mind describing the scenery for me?”
The Collector’s steady stride faltered, and his steps slowed. Good. Aneira was growing weary of his relentless pace.
What he said next surprised her.
“How long have you been blind?”
His gentle tone was unexpected, a crack in that menacing wall surrounding him.
“I started losing my eyesight almost fifteen years ago, when I was five, just after my parents and I moved to Inis Seisear,” she admitted. “My glamour manifested very late, much later than most Faelorehn, and when my sight began to fade, my parents thought I’d been cursed with a geis by someone.”
She grinned a little, then went on, “I was a headstrong girl. The older children who liked to torment me and the others soon learned that I tolerated none of their nonsense, so I’ve gained a few enemies over the years.”
Quinlan stopped and turned to face her. She couldn’t see it, but she could feel his focus shifting toward her.
“So, you’ve always been a brave woman, then? Standing in the face of fear and daring it to defeat you?”
“No. I’ve just never had much patience for intolerance, cruelty, or bullies.”
Quinlan’s bright aura pulsed before her, not enough to cause alarm, but just enough for Aneira to take note. She wondered what it meant. Before she could voice her concern, however, Quinlan was leading her away once more.
“Heather and holly and hawthorn grow mostly on my island. We will climb a short hill to my home, then you can rest.”
It took Aneira a few moments to recall the start of their conversation, and she smiled as that hairline crack widened just a bit more. Before she could press Quinlan with any more questions, he was leading her up the hill and into the welcoming darkness of his home. Her home now, at least for the next year.
Aneira didn’t know what to make of the inside of Quinlan’s home. The darkness that enveloped her soon disappeared as he brought a banked fire back to life, the delicious scent of wood smoke quickly overpowering the hints of dust, leather, sandalwood, and lavender tainting the air. The floor beneath her boots was stone, but as she stepped carefully about the room, she detected rugs spread upon the ground like autumn leaves peppering a forest floor.
“There is an extra bed in the attic upstairs. It should be large enough for you. I reside in the room down the narrow hallway.”
Aneira found her room without trouble, following the stairs up into the small attic. She also discovered a bay window with a bench, her fingertips sinking into soft cushions and brushing up against cool glass. With nothing else to occupy her time, she collapsed onto the narrow bed and tried not to think about her parents crying after her. She loved them dearly, but they had never once given her the chance to prove she could be independent. This was her chance, even though she was at the mercy of the Collector. Some deep-seated instinct, her glamour perhaps, convinced her she would find what she was looking for here, with a man whom all the others despised.
Aneira drew in a deep breath and curled beneath the soft blankets. Not such a bad place after all, this secluded stone cabin. In a few minutes, she was fast asleep and dreaming of waves and monsters, and brave maidens defying them both.
Aneira woke the next morning to the muffled sound of voices. Two, no, three deep, masculine voices. At first, her heart thudded in her throat, and then she remembered where she was: On Inis Seacht, the Collector’s island.
Stretching out of bed, she crept downstairs, using her hands to guide the way. A soft breeze wafted in through a window somewhere, and as Aneira drew nearer, the voices became more clear.
“There should be more,” one man groused.
“What I have supplemented should suffice. It should be more than enough,” the Collector replied gruffly.
“That is not what we’ve come to expect. Not what the Morrigan has come to expect,” a second man added.
“It is all the goddess will get this year. Good day, gentleman.”
Quinlan’s sharp rebuke surprised Aneira.
The crunch of boots on gravel and barely discernible muttering drifted away just before the door squeaked open.
Aneira gasped and whirled around to face the opposite wall.
The Collector’s bright essence filled the room, and she squinted her eyes, even though it did nothing to dim his light.
“Spying on me? Is that why you insisted on taking the place of your parents’ tithe?”
“I wasn’t spying! I heard voices and came downstairs.”
“Never mind,” Quinlan bit out. “Do you know how to cook?”
Aneira squared her shoulders and faced the brilliant light that was the Collector.
“No. My mother refused to teach me. She feared I might injure myself around the fire and hot stove.”
Before Quinlan could make a reply, she hurried on, “I wish to learn, though. I’m sure I will learn fast if you would just show me.”
A long, terrifying pause, and then the Collector spoke.
“Very well. We’ll start with building a fire in the stove, then move on to boiling water and making simple broths.”
Aneira almost cried with joy, but quickly tamped down her delight so as not to appear too eager. For the rest of that day, Quinlan patiently walked her through the process of preparing a simple meal and by mid-afternoon, she had even managed to brew a fresh pot of tea for them to share.
The days passed by quickly this way, with Aneira learning how to prepare the daily meals and picking up new skills along the way. Besides cooking, Quinlan taught her how to mend tears in clothing, light and bank the fire in the hearth, and keep the stone cottage neat and tidy. With her fingertips and the speck of vision she had left, Aneira learned her way around the cabin and took pride in helping keep it organized. The autumn days grew shorter, and if the weather was mild, Quinlan would take her with him to harvest mushrooms, berries, and chestnuts from the grove on the northern side of the island.
“I miss seeing the autumn colors the most,” Aneira admitted, as they began their trek back to the cabin one afternoon.
“Then, let me describe them to you,” Quinlan offered.
Aneira listened intently as he painted a brilliant image of gold, crimson, and ochre within her mind. Despite the chill weather and being away from the village she’d called home for many years, her heart was light and happy. Free.
As they neared the base of the hill, the Collector reached back to take her hand so she might not trip on the walk up. And for the first time since coming to this place to live with him, she appreciated, and savored, that small contact.
When they reached the garden and stepped through the stone gate, Aneira slowed her steps, causing Quinlan to pause with her.
Like always, she could not see his face, but she studied that bright spirit burning before her. Aneira reached out to touch his face, craving more than that comforting grip on her hand, but Quinlan hissed and pulled away.
“Do not touch me!” he growled, whipping his cloak aside and leaving her in a hurry.
Aneira stood out in the garden until the light of the world dimmed around her. Long enough for the tears to dry from her face.
The winter months soon nipped at the heels of autumn, the ice and snow and cold winds from the mountains to the north blowing their frosty breath down upon the lowlands and over the black surface of Lake Ohll. Aneira spent most of her time cooped up in the cottage with Quinlan, continuing her various lessons. The enigmatic Faelorehn man never mentioned her attempt to brush her fingers against his face, and she kept it tucked away as well. It did not do to dwell on disappointment, and the last thing Aneira wished to do was broach a subject that would only drive a wedge between them.
Eventually, winter melted away into spring, and Quinlan started his wanderings again. Aneira was able to follow him with her glamour, stretching her magic out far enough to find his, a firefly flickering on the edge of her consciousness. While he was gone, she would practice all the new tasks she’d learned, or wander out into his walled garden and tend to the young plants there.
One afternoon, Quinlan returned to find her kneeling in the onion beds pulling weeds.
“What are you doing!?” he shouted, crashing through the gate in his haste to reach her.
Shocked, Aneira fell back, her muddied hands held up before her.
“I’m taking out the weeds!” she insisted, her sightless eyes wide.
Before Quinlan could roar at her again, she added, “I can tell them apart from the vegetables, I swear it. Their spark is different from the onions, cabbages, and turnips. See for yourself.”
She groped around on the ground, scooping up the discarded plants she had pulled free of the earth.
Quinlan took her hands in his, his touch gentle despite his earlier outrage. Aneira was reminded of the day he pulled away from her and tried not to shiver. His fingers were rough, his palms scarred. She allowed her glamour to flow free, and the blazing torch that was his soul flared before her. Warm, brilliant, and blinding, in its own way.
“Forgive me,” was all the Faelorehn man said, before dropping her hands and disappearing into the cabin.
Aneira stared at the spot where he had been standing, wondering if he would ever see her the way she saw him.
Quinlan did not protest Aneira’s time spent in the garden from that day forth, and Aneira found the small patch of earth to be a place of healing solitude. She could breathe in the scent of wildflowers, listen to the trickling of a small stream somewhere on the other side of the wall, revel in the sound of birdsong filling the mighty oak that offered shade on particularly warm days.
During those long evenings, after the meal was prepared, Quinlan would sit in his large chair and select a book from his collection. He most often chose the fae tales to read, and upon Aneira’s insistence, he would read them aloud.
“I never learned how to read,” she told him as she prepared the fire, for the nights were still chilly. “That was the one thing I never insisted on learning to do.”
There had been no point, after all. Her eyes were not strong enough to discern the words on a page.
“Then, I shall read every story aloud, so that no matter where you are in the cottage, you will hear them,” Quinlan replied before beginning.
Aneira paused in her chore, the kindling she’d been arranging in the hearth dropping into the ash below. Quinlan’s words made her smile, but before she could linger over them, he delved into a story of adventure and intrigue.
When he finished the tale, Aneira took a deep breath and said, “Tell me another story, Quinlan. Tell me why you live alone on this island. Why you travel to the others once a year to strip us of our surplus of food and goods. I have seen your soul. I have been here nearly a year, and you’ve made a valiant effort to hide your true nature from me. But I have seen your goodness, despite my blindness.”
She touched a hand to the corner of one eye, smiling despite the tightness in her throat, hoping he watched her face. Praying he could read her emotions as well as she had learned to read his.
“I can see everything that matters, because I do not have my sight to distract me. I can feel everything. So, tell me. What curse has befallen you?”
Quinlan was quiet for a very long time, the only sound in the room being the crackle of the fire.
“Quinlan?”
The whisper-soft sound of the Collector rising from his chair was swiftly followed by a curt, “The evening grows late. I bid you good night, Aneira.”
Before she could formulate a reply, the overpowering glimmer of her reluctant captor’s aura faded away down the hall before finally blinking out behind his bedroom door.
“Autumn has come to greet us once again,” Quinlan said absentmindedly one late afternoon as he and Aneira tended to the small garden behind the stone house.
It had been several weeks since Aneira had asked after his geis, his curse, and although he had been polite and continued to teach her and guide her in the many tasks around the cottage, he had been careful to keep his distance. And now Samhain was a day away. She’d been with him so long, and yet, she still had no idea what he looked like. And that had nothing to do with her blindness. Feeling bold, Aneira stood from the flower bed she’d been weeding.
“May I touch you?” she asked, her voice strong, her spine straight as she lifted both her arms.
The request shocked Quinlan, and he jerked back slightly, away from Aneira’s reaching hands.
“Why?” was his gruff reply.
“It’s how I see things, well, the physical aspect of things,” she answered, her mouth cut in a stubborn line.
“Very well,” Quinlan finally conceded, standing absolutely still, his hands balled at his sides.
Aneira smiled, her beautiful gray eyes bright as silver, despite their malady.
She reached out, running her fingers along Quinlan’s rough cheek. The first brush of Aneira’s touch against his face had Quinlan’s eyes drifting shut. His heart pounded in his chest, and his breathing deepened. He had never been touched before, not like this, and it took everything in him to keep from reaching out to her and doing the same.
Her fingers traced the various scars marring his face, ran along the ridges of his cheekbones, and traced the bridge of his nose before coming to rest upon his lips.
Aneira released a deep sigh, and Quinlan tensed, ready for the disgust, or worse, the kind words of pity to fall on his ears. But that was not what happened.
“You are beautiful, Quinlan. I know you feel your face and your body have been ruined and made hideous, and I know that is what the islanders say about you, but it isn’t true. I may not be able to see you with my eyes, but I can see you with my glamour. It has this uncanny ability to reveal a person’s true worth to me. Since that first day you came to my village and took me away in place of my parents’ offering, I could see your soul. I don’t know why, but I do know that you are not the monster the villagers have always painted you to be.”
A hot tear spilled from Quinlan’s eye and trailed down his mangled face. In that moment, he wished he had Aneira’s gift. He wished he could see her spirit the way she saw his. He imagined it shone like the brightest star in the winter sky. The thought, to his surprise, wasn’t all that daunting. But the sentiment behind it frightened him.
“You cannot stay here any longer, Aneira. You’ve paid off your family’s debt.”
Quinlan’s voice was clipped, though it shook ever so slightly.
When Aneira answered, her own tone wavered. “What about for this coming year? And the next? Surely my parents are in the same situation as last year. How will they pay their tithe if I do not stay?”
“Then, I will not ask it of them,” Quinlan replied, his tone hard, unyielding.
Aneira drew breath to argue, but the Collector snarled, “Enough! I leave to gather what is owed to me in the morning. When I return, you will not be here.”
With a swift flick of his cloak, Quinlan turned on his heel and walked back to the cottage, leaving Aneira to shiver in the cold shadow of his absence.
The next morning, Aneira woke to the sound of frantic voices.
“She must be here somewhere,” someone said.
“Locked up in that ramshackle cabin, or perhaps tied to that sickly oak tree.”
Tears spilled down Aneira’s face. The cabin was not ramshackle, and the oak was not sickly.
“We must get her out of here before that monster returns,” a third voice hissed.
“What is it he said, Harold? That the girl had outlived her welcome? More of a drain on his resources than any help? Disgusting, that beast. Perhaps he is as blind as our Aneira to not be able to see her beauty.”
Pain lanced Aneira’s heart, but she had no other choice but to meet these villagers, her old friends. Quinlan wanted her gone. With a heavy heart, she stepped from the cabin and walked down to them. She could sense their sparks of life, nothing compared to the blazing inferno that burned beside Quinlan’s heart.
He is tired of your chatter and nonsense, girl. It is time to return home.
The village of Inis Seisear was overjoyed upon seeing Aneira’s safe return. Her parents rushed out to greet her, her mother raining down kisses and her father checking her arms and neck for any injuries.
“You are unhurt?” he asked, disbelief in his voice.
“I’m not hurt,” she replied.
Except for my heart.
That evening, the Collector of Inis Seacht returned, demanding his tithe. This time, more than required was brought forth, for the villagers feared the creature might make off with their sons or daughters since Aneira had been returned.
Aneira stood at the back of the crowd, her father all but demanding she remain home for the event.
“I will go,” she insisted, still as stubborn and headstrong as ever. She would see him again, even if it was only that bright, burning soul of his, and even if he had no desire to see her.
And so, she accompanied her parents into town. She had watched the pale glowing bits of light that represented her friends and family, and had drawn in her breath when Quinlan’s brilliant burst of luminosity outshone them all. It seemed brighter now, more vibrant. A happy essence glad to be rid of her, perhaps.
The bounties were given over, and the townsfolk retreated to their own bonfire to celebrate the Samhain festival. While she watched the bright flames glow within her fuzzy vision, Aneira realized she’d never gotten Quinlan’s story from him. When she mentioned this to her mother, the other Faelorehn woman quickly rattled off the tale to her curious daughter.
“Oh, the story goes that he got onto the wrong side of things with the Morrigan, and not only did she disfigure him, but she placed a geis on him to remain on that island for all his days, only allowed to leave once a year to pester us for our goods.”
That night, as Aneira lay awake in her own bed, her mother’s words and her own observations over the past year tumbled around in her head. If Quinlan was a selfish person, his glamour would not burn so brightly. A memory, a year old now, surfaced in her mind. The sound of voices outside the Collector’s cabin. Their complaint that there hadn’t been enough . . . enough what? And then Quinlan’s own words joined the others: “What I have supplemented should suffice.”
Aneira’s mind churned as she recalled other details: How Quinlan spent most of his days wandering about the island, how he kept a garden and harvested wild nuts, fruits, and other goods. How he worked the way her fellow neighbors did, growing crops and storing them away. Why would he make the effort if the tithe provided him with all he needed throughout the year?
Aneira threw aside the sheets and bolted to her wardrobe. With deft fingers, she laced up her bodice and tied her skirts in place. Grabbing a shawl, she crept to the door, opening it and closing it as quietly as she could. She slinked downstairs and out the kitchen door into the freezing night. Cold air stung her cheeks and coated her lungs, but she did not turn back. Gradually, she picked her way through the sleeping village, reaching the docks ten minutes after leaving her home.
She felt for a sturdy boat, then climbed in, unlooping the rope along the way. She picked up a paddle and closed her eyes, letting her glamour flood her senses and stretch out far beyond her body. There, across the icy, black lake, she detected a tiny, but brilliant, spark of light. Quinlan. With dogged determination, she dipped the single paddle of the boat into the water and pushed off from the dock.
Quinlan was just about to retire for the night when a tentative knock sounded on his front door. He had been reclining in his favorite chair, a book of fae tales opened on his lap, when the interruption came. It was probably a good thing, because his thoughts weren’t lost in the story like they ought to be. No, he was too busy thinking about the delivery of the goods he’d made to the Morrigan’s soldiers, the fuel that kept the geis burning, the payment that kept the greedy goddess away. The battle-worn Faelorehn men had been waiting at his cabin when he’d arrived earlier that evening from collecting the tithes, and relief so strong it had nearly brought him to his knees had washed over him. Aneira was gone. Her people had answered his summons and had come to take her away. These horrible men and the goddess they served would never learn of Aneira and her gifted glamour. They would never be able to harm her as they’d harmed him.
The knock came again, and Quinlan frowned. Perhaps these were the soldiers returning to demand more payment. He would give them whatever they asked, so long as it got them away from his islands and the secrets they held.
The Collector rose and crossed to the door. But the face that greeted him on the other side sent both a wave of shock and joy through him.
“I wanted you to know,” Aneira said, her tone slightly breathless, “that it was my choice to leave my village last year and mine alone.”
Bewilderment soon outshone the Collector’s other emotions.
“You sent me away because you thought I was being punished, but I wasn’t. If I hadn’t wanted to leave with you last Samhain, nothing could have compelled me to do so. I am a stubborn young woman, if you recall.”
Quinlan’s brow pinched in puzzlement, but as he stood there turning Aneira’s words over in his head, it grew suddenly clear to him.
“Your parents did not misplace their tithe,” he said, his voice soft and level.
Aneira nodded, smiling with the first signs of shyness Quinlan had ever seen in her.
“No. As much as it pained me to do so, I took our year’s supply of honey and dropped it in the lake. I was tired of being looked over, tired of being pitied and treated as if I might break into a thousand pieces if I so much as tripped over a stray stone in the street. I felt trapped in that village, Quinlan. I had to get out, by any means necessary.”
“Even if it meant spending a year of solitude on an island with the likes of me?” the Collector asked.
Aneira shook her head again, her pale gray eyes brimming with tears.
“And what of you, Quinlan? I heard you the morning after Samhain. I heard you speaking with those men, the Morrigan’s soldiers. The tithe you collected from all the islands, you handed it over to them, didn’t you?”
Quinlan remained silent.
“This is why you still farm and harvest from the land. It is because you still need to provide for yourself. The tithe was not for you, it was for them. I think it is time for you to tell me your story, Quinlan. No more excuses.”
With a heavy sigh, the Collector stepped aside, inviting Aneira into his cottage. When they were both comfortably seated, he began his tale.
“Many years ago, the Morrigan sent scouts to these islands to recruit soldiers for her armies. I was young then, about your age, and fancied myself brave. I was trying to impress the young women of my village, so I told the soldiers to look elsewhere. My glamour was strong, and I was able to resist their attempts to make off with the men and women old enough to serve the goddess of war and strife. Twice more they returned, each time warning me the Morrigan would curse me with a geis should I not comply. Feeling confident in my magic, I sent them away again. The next time someone came for us, it was the Morrigan herself.”
Quinlan paused to take a breath before he continued.
“She flew into the village square in her raven form, transforming into a woman before touching the ground. Her dark glamour was terrible and stronger than anything I had ever felt. In that moment, I realized what a fool I had been. Before I could beg for mercy, she swept her magic over me, scarring my face, arms, and hands, claiming that if not for my pride, I would have listened to sense and joined her cause without a fight. She left me there, damaged and screaming, unable to break free of the hold her glamour had on me, as she took not only those old enough to fight, but all the people of our islands. She told me that I would be left to guard this place, and if people decided to move in again, she would come and take them, like cattle to the slaughter.”
Quinlan paused for a moment, but Aneira didn’t dare speak.
“But the goddess of war is cruel, and she told me that I could stop this from happening. I could continue to refuse and resist her, if I wished, but she would take her payment in one form or another. I was disfigured now, she reminded me, and I could use that to my advantage.
“You can continue to protect your flock, little shepherd, but in order to do so, you must take from them every year something of value. They will fear you, because of what you have become. They will grow to despise you and they will cast you out. And every year, on Samhain, you will visit these islands and demand payment from them for my sake. Or, you can let me recruit from their number each year.”
“I chose to ostracize myself, for it was because of my pride that my family and friends were torn from me to be used in the Morrigan’s bloody battles. I deserved to be set apart, and I would take on the role of the cruel monster who demanded payment from them every year because I didn’t want them to suffer the same fate as those before them. And because I deserved to be hated and despised.”
Silence, dark and heavy, fell over the room, and it took a long while for Aneira to find her voice.
“You’ve saved us all, Quinlan. You resisted the Morrigan’s demand and because of it, we remain safe from her evil grasp.”
“And I remain cursed, destined to live out my mortal existence alone on this island.”
His tone held bitterness, but not regret.
“You do not have to be alone anymore, Quinlan. I can see past that wall of anger and bitterness you have built up around yourself. My glamour can see you, and you are one of the most selfless men I have ever known.”
Aneira reached out to touch his face, and for once, he did not protest; he did not pull away. His skin was rough and smooth and warm, just as she remembered. Aneira smiled, tears forming in her eyes.
“I do not deserve you,” Quinlan murmured, his voice rough, as he turned his face into her touch. “I could never deserve you.”
“Perhaps not, but you need me, and I need you. It’s time we stop fighting what brings us the most joy.”
She leaned into him, encircling his waist with her arms, pressing her ear to his chest. His heart thrummed strongly beneath his tunic and when he stood from his chair, his arms tightening about her to pull her close, happiness radiated from her in brilliant waves. And that beautiful light that made up his soul shone so bright, it encompassed them both.
Posted by AuthorJEJohnson at 9:26 PM 5 comments:
Labels: A Fae Tale of Eile, Fairy Tales, Free Reads, Otherworld Series, The Curse of Inis Seacht
A Brand New Short Read from Jenna Elizabeth Johnso...
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Jobbik: This is sign of government crisis
Jobbik expects an immediate answer why the Minister of Defence resigns in this critical situation
In emergency national unity is top priority
Jobbik held its third anti-immigration demonstration, this time in Budapest.
Jobbik wins: no transit zone in Budapest!
Jobbik conducted a series of demonstrations against the planned construction of a Budapest transit zone (i.e. new refugee camp).
Jobbik knocks out government party Fidesz in Tapolca by-elections
Both of Jobbik's candidates have won the by-elections in the city of Tapolca. This means that the party has the majority in the municipal council now.
How much does the daily care of immigrants cost?
On average, the daily care of asylum seekers costs 4300 HUF each. Today, the daily unemployment benefit is 2362 HUF per day.
Jobbik condemns Hungary's contribution to the US' show of force
Jobbik Movement for a Better Hungary expresses its concerns about the participation of the Hungarian Defence Forces in the protection of the Baltic states' airspace and considers the act extremel
Jobbik to revoke voting rights from migrants who are granted asylum
Jobbik urges to revoke the voting rights – valid for the municipal elections – of immigrants whose applications for asylum were approved.
The integrity of Hungary's national borders cannot be protected without the Hungarian defence forces
Jobbik will submit a motion to amend the Constitution to provide the proper legal grounds for deploying the Hungarian Defence Forces in order to protect Hungary's borders
Jobbik says soldiers may be needed to protect border
The option of deploying soldiers to protect Hungary’s border against the influx of migrants should be examined, the radical nationalist Jobbik party said on Monday.
What Hungary needs is neutrality instead of American tanks
Jobbik categorically condemns the government's irresponsible policy which exposes Hungary as a potential theatre for the military conflicts of great powers
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Tag: Kingfisher chairman Vijay Mallya
Mallya in trouble as Kingfisher pilots plan to move labour court
Posted on July 15, 2012 | by Legal India Admin | Leave a Comment on Mallya in trouble as Kingfisher pilots plan to move labour court
Kingfisher chairman Vijay Mallya may found himself in trouble as Kingfisher pilots are planning to move labourr court. With the Kingfisher Airline management maintaining a stoic silence over the payment of salary dues, a section of its pilots are contemplating to drag the management to the labour court, sources said.
Vijay Mallya who is passing through tough time, is getting new and new problems every day. Financial weakness creating new problems for him. Kingfisher Airlines is currently facing heavy debts.
“(Airline) Chairman Vijay Mallya’s communication to the employees conceals more than it reveals. While he claims over 75 per cent staff have been paid, he conveniently ignores the fact that he has still to pay four months’ salaries to them. Now we have come to a situation where we are left with no option but to move the labour court over the issue,” according to airline sources.
A group of pilots are in consultation with lawyers in this regard, they said, adding that they are likely to move the court some time this week.
In the absence of a trade union at the airline for its nearly 1,700 employees, the pilots are planning to approach the court in groups, they said.
Notably, none of the five private airlines have trade unions. A few years back, a group of Jet pilots had tried to form a union, but the move was nipped in the bud by the management.
The debt-ridden airline has paid February salaries to around 75 percent of the staff, while the rest are yet to get their dues.
“Unfortunately, the airline is keeping mum on when it will pay the salaries for March, April, May and June,” they said.
Mr. Mallya, who shot off an emotional letter to his staff yesterday after a large number of its employees went on a strike leading to cancellation of over 40 flights, had said, “The commitment made by chief executive Sanjay Aggarwal and executive vice president Hitesh Patel regarding salaries recently have been met to the extent of 75 percent.”
Mr. Mallya, however, gave no assurance by when the remaining salary dues would be cleared.
He also asked the agitating employees not to talk to the media or “disgrace” the company saying it would affect the recapitalisation efforts.
Reacting sharply to Mr. Mallya’s letter, some pilots had said there could not be a bigger disgrace to the company than defaulting on payments to its aircraft lessors, airport operators, oil marketing firms, the government, apart from the salaries of its employees.
Meanwhile, Kingfisher Airline said that all its scheduled flights are operating normally.
“All our scheduled flights will now be operating normally with immediate effect (July 15),” a Kingfisher airline spokesperson said.
When asked whether the pilots had called off their agitation and airline had given any assurance that the remaining employees will be getting their February salaries on Monday, the spokesperson refused to offer any comments.
Posted in Top Law News | Tagged Kingfisher, Kingfisher chairman, Kingfisher chairman Vijay Mallya, Kingfisher pilots, Labour court, labour dispute, liqor baron Vijay Mallya, Vijay Mallya
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New Jersey General Assembly Approves a Daily Fantasy Sports Bill
By Cliff Spiller
May 23rd, 2017 | Last updated on November 2nd, 2018
Home » Poker News » New Jersey General Assembly Approves a Daily Fantasy Sports Bill
A bill to legalize, license, and regulate daily fantasy sports in New Jersey was passed by a wide margin in the General Assembly on Tuesday. The measure passed in the Democrat-controlled Assembly by a 65-15 vote, and now passes to the State Senate for a vote.
Assembly Bill 3532 would regulate the daily fantasy sports industry in New Jersey, allowing operators like DraftKings and FanDuel to seek a license. If the new law were to pass, operators would need to pay a quarterly fee of 10.5% on all daily fantasy sports revenues they collected.
Regulation by Division of Consumer Affairs
In keeping with the official stance that DFS is not sports betting, oversight would not be under the aegis of the Division of Gaming Enforcement. Instead, the Division of Consumer Affairs, an office withing the Department of Law and Public Safety, would have oversight duties.
Steven C. Lee is the current director of the Division of Consumer Affairs.
The Division of Consumer Affairs would issue permits for all fantasy sports operators, while also reviewing racetrack licenses and casino licenses. The DCA’s authority would include audits of monetary reserves (operating cash), along with the regulation of other financial guidelines.
Regular Fantasy Sports Unaffected
Small-scale fantasy games between family, friends, and coworkers would not be affected under AB 3532. That means local fantasy leagues or “yearly fantasy football” would not have to register or pay taxes on their gaming receipts. Daily fantasy football is an offshoot of the traditional local leagues, as DFS has one-day contests more akin to a sport bet.
Keeping in mind the exclusion for small-scale fantasy games, A3532 bans underage gaming under the age of 18 on DFS sites. The bill bans individuals with financial interests in the fantasy industry, including employees and investors, to play DFS in the state. It also bans fantasy gaming on high-school sports.
New Jersey’s Sports Betting Appeal
General Assembly Bill 3532 comes at a time when New Jersey is at a crucial juncture in its campaign to legalize sports betting in the state. After 5 years and 5 lost court decisions, New Jersey has appealed its challenge to the 1992 PASPA sports betting law to the U.S. Supreme Court. The court has not yet decided to hear the appeal or not, though Active U.S. Solicitor General Jeffrey Wall has called on the Supreme Court to reject the appeal.
Some officials in New Jersey do not want to pass the DFS bill while the sports betting appeal remains unresolved. If the state was seen supporting a similar form of sports gaming, some believe it could undermine the PASPA appeal. For that reason, it is unlikely the State Senate would pass A3532 — or Gov. Chris Christie would sign it into law — until the Supreme Court announces its decision.
Hard Times for the DFS Industry
The move comes at a hard time for the daily fantasy sports industry. The Fantasy Sports Trade Association released a statement in April 2017 suggesting that two-thirds of the notable daily fantasy sports operators in the United States either have been bought out by a competitor or closed entirely in the past year.
The DFS industry is in the midst of a major lobbying effort to see individual US states legalize and regulate daily fantasy sports. The cost of those efforts, along with the constriction of revenue sources through bans in several major US states, has been too much for some of the less lucrative DFS operations.
FanDuel-DraftKings Merger Talks
Even FanDuel and DraftKings, who control 95% of the market between them, have faced their own struggles. The two companies have shouldered the burden of lobbying and legal battles for the industry, while seeing their revenues in Texas, Illinois, and New York State taken from them by bans (New York’s legislature later regulated the industry).
Due to those efforts, FanDuel and DraftKings are in the midst of merger talks which would change the face of the industry. It is a far cry from two years ago, when the two DFS giants were in a massive marketing campaign to see who would be No. 1 in the DFS industry. At the time, both companies were signing partnership deals with US sports leagues and individual franchises, while obtaining hundreds of millions of dollars in investments from major New York City investment firms and media outfits.
The decision by NFL, NBA, MLB, and NHL league offices and franchise owners to sign sponsorship deals with DraftKings and FanDuel led to charges of hypocrisy by many gaming media and fan groups. The major sports leagues want to ban sports betting based on “public confidence” and “the integrity of the game”, yet sign deals with sports gaming interests. The leagues argue that DFS contests are harder to rig, because they involve the outcome of 15 to 20 players (or more) competing in two or more games, instead of a single game’s outcome.
About A 3532
The sponsors for the bill in the General Assembly are Vincent Mazzeo, Ralph Caputo, John J. Burzichelli, Paul Moriarty, and Thomas Giblin. An identifcal bill, S1927, will have a vote in the New Jersey Senate. The sponsors of S1927 are Jim Whelan and Brian P. Stack.
About Cliff Spiller
Cliff Spiller has been an online writer for 14 years. He worked for Small World Marketing for a decade, where he covered topics like gaming, sports, movies, and how-to guides. Since 2014, he has blogged about US and international gambling news on BestOnlineCasinos.com, USPokerSites.com, and LegalUSPokerSites.com
View all posts by Cliff Spiller
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Best Performances Snubbed By Oscars Of-Late
Movies>
There are good performances and there are award-winning performances. And then, there is the third kind- performances that grasp you masterly, but fail to hold onto any awards. ‘Oscars’ is what I am talking about here. This list is about few such acts:
Leonardo DiCaprio in ‘Django Unchained’ and ‘The Departed‘
No need for immersible angles, there he is. Scarring the skin of his character layer by layer, Leonardo perches himself comfortably in its body. For bareness, the man can’t be beat — nor for brilliance. In Tarantino’s anti-state of art masterpiece, you should be rooting for Django, but you might as well be rooting for the evil Calvin Candie. Most likely, you will be rooting against anyone who doesn’t let Candie have his way! The stream is originating from Leonardo’s character in ‘The Departed’. The man living under a 24 hour angst and devastated by panic-attacks, has been played by the most excellent Mr. Caprio in such a quicksilver spirit that you start giving a damn about who wins what between Costello and Queenan.
And did Leonardo Di Caprio get an Oscar nomination for either of these roles? NO.
Live with that.
Robert Duvall in ‘Get Low’
(Let me begin in a rule-busting way)
He ain’t need no dialogues. He ain’t need no histrionics. He ain’t need no make-up. He is Robert Duvall- the monument of Hollywood. Make him stand in just a fraction of the frame and he will chew up the whole screen, literally (If you have seen his performances close enough, you will know). In the psychologically idiosyncratic ‘Get Low’, Robert Duvall plays a backwoods hermit, a demonized old boy living in exile from last 40 years. Whilst he has been a much-detested loner, he desires to die amidst celebration. And this is why he plans his own funeral party, while he is alive, while he is there! He wants everyone to come and tell a story about him
The best lines in the film are reserved for Duvall, but he may have not even needed those for his bare-knuckled performance. In lesser hands, this role would have compromised into a banal swaggering attempt. The first time director, Aaron Schneider is blessed with a superlative cast- Robert Duvall, Sissy Spacek and Bill Murray and he does more than justice. Academy wasn’t impressed.
Kate Winslet and Leonardo Di Caprio in ‘Revolutionary Road’
Alright, Kate won herself an Oscar for ‘The Reader’, but to be honest, it was one of the weakest holocaust flicks to have come in a long time, and even Kate Winslet didn’t look like that ‘lone bright spot’. She was fine- Nothing more, nothing less. Revolutionary Road, a movie which itself deserved a far-better deal, bought the better in her as an emotionally tarnished woman who wants to live a ‘goddamn fantasy’. Leonardo Di Caprio is brutal in his versatility and that’s what is up for display- a performance like a consummate work of art. Kate and Leonardo are like dancing partners, matching beat to beat and transcending the hollowness that lies somewhere in the making of the film.
These are actors who have a range of natural impulses that lend a restrained yet intense and authentic feel to all of their characters. Rest assured, they will not let you ever imagine anyone else in their roles.
Only if the Academy could see!
Tags: academy, acting, film, kate winslet, Leisure Martini, Leonardo DiCaprio, Leonardo DiCaprio and kate winslet, movies, oscar, Oscar snubbed actors, oscar snubs, performance, robert duvall, role
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Josiah-David
16 Jun 2016 Reply
Must see!
“Male Celebrities who are SO MUCH Hotter and Talented than Leonardo DiCaprio” ! 🙂
http://www.imdb.com/list/ls058930557/
Thank me later. 😉
Well that’s a heartfelt write-up you have there! First things first, I’m not some crazy Leonardo fan as this post might make me look like. Second, I guess you need to look at his career beyond Titanic. So movies like Departed, Revolutionary Road, Blood Diamond, Wolf of wall street, etc show his amazing range (he does become the character he is supposed to become)
So let’s just agree to disagree. 🙂
Leave a Reply to Rohit Raina Cancel reply
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The Code of Hammurabi King of Babylon. About 2250 B.C. Autographed...
Harper, Robert Francis. The Code of Hammurabi King of Babylon. About 2250 B.C. Autographed Text Transliteration... Originally published: Chicago: The University of Chicago Press, 1904. xvi, 192, [ii] pp., [i], ciii plates, including map of the region. Reprinted 2010 by the Lawbook Exchange, Ltd. ISBN-13: 9781616190521; ISBN-10: 1616190523. Paperback. New..... More
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Athenian Roots of International Law Cohen, Edward E. Ancient Athenian Maritime Courts. Originally published: Princeton: Princeton University Press, [1973]. xii, 233 pp. Reprinted 2005, 2010 by The Lawbook Exchange, Ltd. ISBN-13: 9781584776611; ISBN-10: 1584776617. Hardcover. New. $29.95 * Athens was the dominant maritime power in the West from the eighth..... More
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Probert, William, Translator. The Ancient Laws of Cambria: Containing the Institutional Triads of Dyvnwal Moelmud, the Laws of Howel the Good, Triadical Commentaries, Code of Education, and the Hunting Laws of Wales, to Which are Added, the Historical Triads of Britain. Originally published: London: Sold by E. Williams, 1823. iv..... More
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McIlwain, Charles Howard. Constitutionalism: Ancient and Modern. Originally published: Ithaca: Cornell University Press, 1940. ix, 162 pp. Reprinted 2005, 2017 by The Lawbook Exchange, Ltd. ISBN-13: 9781584775508. ISBN-10: 1584775505. Hardcover. New. $24.95 * Reprint of the first edition. Upon publication The Law Quarterly Review praised this book, noting that "great..... More
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Lectures on the Growth of Criminal Law in Ancient Communities
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Babylonian and Assyrian Laws, Contracts and Letters.
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ERIC JOHNSON Classics: Present and Past
Eric Johnson is touring in celebration of his 1990 release Ah Via Musicom, which was certified platinum plus and launched Eric's signature hit "Cliffs Of Dover," which won the Grammy for Best Rock Instrumental Performance. Eric will be performing with an electric band on this tour.
Johnson leapt to the forefront of contemporary music some 20 years ago as "an extraordinary guitar player accessible to ordinary music fans," as the Memphis Commercial Appeal hails him, with his landmark album Ah Via Musicom. Lauded as a "recording [that] has reached near-classic proportions within the guitar community" by All Music Guide, it was preceded by dedicated groundwork as a live performer that marked him as a talent bound for great things. And it's been followed by a diverse and fascinating musical journey that inspired The New Age Music Guide to rave that "Eric Johnson plays guitar the way Michelangelo painted ceilings: with a colorful vibrancy that's more real than life."
Fender Guitars will also be launching its Eric Johnson Signature "Thinline" Stratocaster to coincide with this tour.
Categories: Music , All Shows , Outside Presenter
Sun. Jan 26
AEG Presents
Regular $35/$30
Jason Vieaux
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Difference between revisions of "Coordinative Learning"
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At the micro-level, the overall hypothesis is that robust learning occurs when the [[learning event space]] has target paths whose [[sense making]] difficulties complement each other (as expressed in the first bullet above) and the students make path choices that take advantage of these [[complementary]] paths (as in the second bullet, above). This hypothesis is just a specialization of the [[Root_node|general PSLC hypothesis]] to this cluster.
<br><center>[[Image:cl-theory.jpg]]</center>
1 The PSLC Coordinative Learning cluster
1.6 Hypotheses
The PSLC Coordinative Learning cluster
The studies in the Coordinative Learning cluster tend to focus on varying a) the types of information available to learning or b) the instructional methods that they employ. In particular, the studies focus on the impact of having learners coordinate two or more types. Given that the student has multiple sources/methods available, two factors that might impact learning are:
What is the relationship between the content in the two sources or the content generated by the two methods? Our hypothesis is that the two sources or methods facilitate robust learning when a knowledge component is difficult to understand or absent in one and is present or easier to understand in the other.
When and how does the student coordinate between the two sources or methods? Our hypothesis is that students should be encouraged to compare the two, perhaps by putting them close together in space or time.
At the micro-level, the overall hypothesis is that robust learning occurs when the learning event space has target paths whose sense making difficulties complement each other (as expressed in the first bullet above) and the students make path choices that take advantage of these complementary paths (as in the second bullet, above). This hypothesis is just a specialization of the general PSLC hypothesis to this cluster.
Coordinative Learning glossary.
Co-training
Conceptual tasks
Contiguity
Ecological Control Group
External representations
Input sources
Instructional method
Multimedia sources
Procedural tasks
Self-explanation
Self-supervised learning
Unlabeled examples
When and how does coordinating multiple sources of information or lines of reasoning increase robust learning?
Two sub-groups of coordinative learning studies are exploring these more specific questions:
1) Visualizations and Multi-modal sources
When does adding visualizations or other multi-modal input enhance robust learning and how do we best support students in coordinating these sources?
2) Examples and Explanations
When and how should example study be combined and coordinated with problem solving to increase robust learning? When and how should explicit explanations be added or requested of students before, during, or after example study and problem solving practice?
Content of the sources (e.g., pictures, diagrams, written text, audio, animation) or the encouraged lines of reasoning (e.g., example study, self-explanation, conceptual task, procedural task) and combinations
Instructional activities designed to engage students in coordination (e.g., conceptual vs. procedural exercises, contiguous presentation of sources, self-explanation)
See Category:Independent Variables
Normal post-test and measures of robust learning.
When students are given sources/methods whose sense making difficulties are complementary and they are engaged in coordinating the sources/methods, then their learning will be more robust than it would otherwise be.
There are both sense making and foundational skill building explanations. From the sense making perspective, if the sources/methods yield complementary content and the student is engaged in coordinating them, then the student is more likely to successfully understand the instruction because if a student fails to understand one of the sources/methods, he can use the second to make sense of the first. From a foundational skill building perspective, attending to both sources/methods simultaneously associates features from both with the learned knowledge components, thus potentially increasing feature validity and hence robust learning.
Visualizations and Multi-modal sources
Contiguous Representations for Robust Learning (Aleven & Butcher)
Mapping Visual and Verbal Information: Integrated Hints in Geometry (Aleven & Butcher)
Visual Representations in Science Learning (Davenport, Klahr & Koedinger)
Co-training of Chinese characters (Liu, Perfetti, Dunlap, Zi, Mitchell)
Learning Chinese pronunciation from a “talking head” (Liu, Massaro, Dunlap, Wu, Chen,Chan, Perfetti) [Was in Refinement and Fluency]
Examples and Explanations
Knowledge component construction vs. recall (Booth, Siegler, Koedinger & Rittle-Johnson)
Studying the Learning Effect of Personalization and Worked Examples in the Solving of Stoichiometry Problems (McLaren, Koedinger & Yaron)
Note-taking Project Page (Bauer & Koedinger)
Note-Taking: Restriction and Selection (completed)
Note-Taking: Coordination (planned)
The REAP Project: Implicit and explicit instruction on word meanings (Juffs & Eskenazi)
Hints during tutored problem solving – the effect of fewer hint levels with greater conceptual content (Aleven & Roll)
Handwriting Algebra Tutor (Anthony, Yang & Koedinger)
Lab study proof-of-concept for handwriting vs typing input for learning algebra equation-solving (completed)
Effect of adding simple worked examples to problem-solving in algebra learning (completed, analysis in progress)
In vivo comparison of Cognitive Tutor Algebra using handwriting vs typing input (in progress)
Bridging Principles and Examples through Analogy and Explanation (Nokes & VanLehn)
Does learning from worked-out examples improve tutored problem solving? (Renkl, Aleven & Salden) [Also in Interactive Communication]
Scaffolding Problem Solving with Embedded Example to Promote Deep Learning (Ringenberg & VanLehn)
Much research in human and machine learning research has advocated various kinds of “multiples” to assist learning:
multiple data sources (e.g., human learning (HL): Mayer, 2001; machine learning (ML): Blum & Mitchell, 1998; Collins & Singer, 1999).
multiple representations (e.g., HL: Ainsworth & Van Labeke, 2004; ML: Liere & Tadepalli, 1997),
multiple strategies (e.g., HL: Klahr & Siegler, 1978; ML: Michalski & Tecucci 1997; Saitta, Botta, & Neri, 1993);
multiple learning tasks (e.g., HL: Holland, Holyoak, Nisbett, & Thagard, 1986; ML: Caruana, 1997; Case, Jain, Ott, Sharma, & Stephan, 1998);
Experiments in human learning have demonstrated, for instance, that instruction that combines rules or principles and examples yields better results than either alone (Holland, Holyoak, Nisbett, & Thagard, 1986) or, for instance, iterative instruction of both procedures and concepts better learning (Rittle-Johnson & Koedinger, 2002; Rittle-Johnson, Siegler, & Alibali, 2001).
Experiments in machine learning have demonstrated how more robust, generalizable learning can be achieved by training a single learner on multiple related tasks (Caruana 1997) or by training multiple learning systems on the same task (Blum & Mitchell 1998; Collins & Singer 1999; Muslea, Minton, & Knoblock, 2002). Blum and Mitchell (1998) provide both empirical results and a proof of the circumstances under which strategy combinations enhance learning. In particular, the co-training approach for combining multiple learning strategies yields better learning to the extent that the learning strategies produce “uncorrelated errors” – when one is wrong the other is often right. As an example of PSLC work, Donmez et al. (2005) demonstrate, using a multi-dimensional collaborative process analysis, that regularities across multiple codings of the same data can be exploited for the purpose of improving text classification accuracy for difficult codings.
An ambitious goal of PSLC is provide a rigorous causal theory of human learning results at the level of precision of machine learning research.
Ainsworth, S., Bibby, P., & Wood, D. (2002). Examining the effects of different multiple representational systems in learning primary mathematics. The Journal of the Learning Sciences, 11(1), 25–61.
Ainsworth, S.E. & Van Labeke (2004) Multiple forms of dynamic representation. Learning and Instruction, 14(3), 241-255.
Blum, A., & Mitchell, T. (1998). Combining labeled and unlabeled data with co-training. In Proceedings of Eleventh Annual Conference on Computational Learning Theory (COLT), (pp. 92–100). New York: ACM Press. Available: citeseer.nj.nec.com/blum98combining.html
Caruana, R. (1997). Multitask learning. Machine Learning 28(1), 41-75. Available: citeseer.nj.nec.com/caruana97multitask.html.
Case, J., Jain, S., Ott, M., Sharma, A., & Stephan, F. (1998). Robust learning aided by context. In Proceedings of Eleventh Annual Conference on Computational Learning Theory (COLT), (pp. 44-55). New York: ACM Press.
Collins, M., & Singer, Y. (1999). Unsupervised models for named entity classification. In Proceedings of the Joint SIGDAT Conference on Empirical Methods in Natural Language Processing and Very Large Corpora (pp. 189–196).
Donmez, P., Rose, C. P., Stegmann, K., Weinberger, A., and Fischer, F. (2005). Supporting CSCL with Automatic Corpus Analysis Technology, to appear in the Proceedings of Computer Supported Collaborative Learning.
Holland, J. H., Holyoak, K. J., Nisbett, R. E., & Thagard, P. R. (1986). Induction: Processes of inference, learning, and discovery. Cambridge, MA: MIT Press.
Klahr D., and Siegler R.S. (1978). The Representation of Children's Knowledge. In H.W. Reese and L.P. Lipsitt (Eds.), Advances in Child Development and Behavior, Academic Press, New York, NY, pp. 61-116.
Liere, R., & Tadepalli, P. (1997). Active learning with committees for text categorization. In Proceedings of AAAI-97, 14th Conference of the American Association for Artificial Intelligence (pp. 591—596). Menlo Park, CA: AAAI Press.
Mayer, R. E. (2001). Multimedia learning. New York: Cambridge University Press.
Michalski, R., & Tecuci, G. (Eds.) (1997). Machine learning: A multi-strategy approach. Morgan Kaufmann.
Muslea, I., Minton, S., & Knoblock, C. (2002). Active + semi-supervised learning = robust multi-view learning. In Proceedings of ICML-2002. Sydney, Australia.
Rittle-Johnson, B., Siegler, R. S., & Alibali, M. W. (2001). Developing conceptual understanding and procedural skill in mathematics: An iterative process. Journal of Educational Psychology, 93(2), 346–262.
Rittle-Johnson, B., & Koedinger, K. R. (2002). Comparing instructional strategies for integrating conceptual and procedural knowledge. Paper presented at the Psychology of Mathematics Education, National, Athens, GA.
Saitta, L., Botta, M., & Neri, F. (1993). Multi-strategy learning and theory revision. Machine Learning, 11(2/3), 153–172.
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About Health Together
Past Work and Events
To contact the Health Together team please use the details below.
Director of Health Together,
Direct dial: 07780493024
Email: J.White@leedsbeckett.ac.uk
Sue Rooke
Health Together Administrator,
Direct dial: 0113 812 1957
Email: S.Rooke@leedsbeckett.ac.uk
Health Together, CL 518,
Faculty of Health & Social Sciences,
Leeds Beckett University,
Leeds, LS2 8NU
Below we have listed more of the work we have done since Health Together was established in 2012. This includes briefings, reports and presentations from seminars and events as well as project work.
Early in 2013 we were commissioned by the Local Government Association to facilitate a series of area based workshops on a whole system approach to assets based working and health improvement in Walsall, which we did in collaboration with the Federation of Community Development Learning. Find more information here
In early 2013 we were also commissioned by Sheffield City Council to facilitate a series of consultation events to engage the voluntary and community sector in the development of their joint strategic needs assessment. Judy White and Mark Gamsu can be viewed here talking about the events they facilitated.
Play Health Together James Henderson Video
In May/June 2014 Health Together undertook a review of health trainer data for the national Data Collection and Reporting Service. The report of this work summarises health trainer activity in the financial year 2013-2014, using data recorded on the DCRS. Not all health trainer services use the DCRS to record their activity (some use other systems and some do not use electronic systems at all), so the figures in this report do not represent the whole picture of what health trainers are doing nationally. Nevertheless, with approximately 60% of health trainer services still using the DCRS, it is an important central resource for assessing the activity of health trainers in England and the report provides a useful overview of activity in the past year with a particular focus on mental health and wellbeing, in relation to client demographics and achievement of personal health plan goals. The report can be found here.
In January/February 2013 we facilitated group activities at a series of four Joint Strategic Needs Assessment consultation events for Sheffield City Council and provided an on the spot summary of the key points emerging from the groups. We also contributed to a members’ review of public health, advising on what ‘people-centred public health’ might look like.
In the spring and summer of 2013 we undertook an evaluation of a pilot run by East Riding Health Trainer Service which aimed to reach and support fishermen, related workers and their families to improve their health. The pilot was initially funded by the Seamen's Hospital Society and the evaluation involved analysing the monitoring data and case stories collected by the health trainers; talking to clients (eight were interviewed over the telephone); the two health trainers and three stakeholders. The aim of the evaluation was to discover: how far the service had been successful in reaching fishermen and their families: whether the service had been effective in supporting them to improve their health and well-being: what the views of clients were of the service and what factors were key to determining the effectiveness of the pilot.
Strengthening the Voice of Neighbourhoods
In 2013 we did a small piece of work with Locality which involved interviewing the chief officers of four community organisations in Yorkshire with an established track record of providing health and wellbeing services. These views were then tested at a half-day workshop with a larger group of Locality members and the results written up as a briefing which calls for a rebalancing of commissioning to give greater consideration to the needs of communities and neighbourhoods. The recent creation of Health and Wellbeing Boards (HWBs) and Clinical Commissioning Groups (CCGs) provides an opportunity to develop more locally relevant delivery models, however the danger is that without an active local development agenda commissioners will continue to rely predominantly on universal authority level services that do not take sufficient account of localised needs. The briefing sets out a series of recommendations for local and national stakeholders that would enable this rebalancing to occur. The report can be found here.
Strengthening the Voluntary Sector in Calderdale
In 2016 Health Together reviewed the outcome of a £3m programme funded by Calderdale Clinical Commissioning Group and delivered by Voluntary Action Calderdale. The programme aimed to increase the capacity and capability of the voluntary sector in Calderdale - with the aim of strengthening the role of the voluntary and community sector in health and care delivery. A summary of the final report is available here.
Putting 'the public' back into public health - Building the experience of citizens into public health evidence
Getting the experiences of the general public involved in the commissioning of public health activity was the subject of debate at a conference held at Leeds Beckett University.
David Hunter - What Constitutes Evidence in Public Health PPTX
Jane South - Building the voice of citizens into public health evidence - why it's important? PPTX
Mike Kelly - Building the voice of citizens into public health evidence - the view from NICE PPT
Alison Hill - 'Building the voice of citizens into public health evidence - the view from the PHE' PPTX
Recent Seminars
People-Centred Public Health
A new book by Jane South, Judy White and Mark Gamsu, People Centred Public Health, was launched on Friday 15th February 2013. See www.policypress.co.uk.
Dr Ruth Hussey (Chief Medical Officer for Wales) and David Hunter (Professor of Health Policy and Management, Durham University) spoke at the event and a debate on what an equitable and people-centred public health system would look like took place. For links to the talks and debate click on the appropriate link below.
Dr Ruth Hussey
Prof. David Hunter
To view Peter Duncan's presentation "Public Health moves back to local authorities – are there lessons from the recent history of health promotion?" please click here.
To listen back on Dave Bucks presentation "Clustering of Unhealthy Behaviours" please click here.
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Newman’s Flagpole Rock Municipal Heritage Site
Harbour Breton, Terre-Neuve et Labrador, A0H, Canada
Newman’s Flagpole Rock, Harbour Breton, NL
Town of Harbour Breton Website
Located at 9 Newman’s Lookout, Harbour Breton, NL, is a rock outcrop known as Newman’s Flagpole Rock. This rock was the location of Newman and Company’s flagstaff from circa 1790 to circa 1907. The designation is confined to that piece of land known locally as Newman’s Flagpole Rock and a five metre buffer zone extending out from the base of the rock in all directions.
Newman’s Flagpole Rock has been designated a municipal heritage site by the Town of Harbour Breton because of its historic and cultural values.
Newman’s Flagpole Rock has historic value due to its association with Newman and Company, one of the largest English West Country merchant firms to operate in Newfoundland during the nineteenth century. Newman and Company did business with fishermen along the south coast, especially those in Fortune Bay. The firm operated its import and export business in Harbour Breton for over 100 years (circa 1790-1907). Newman’s Flagpole Rock was the location of Newman and Company’s flagstaff for its operation in Harbour Breton and was located in front of the Big House, as the manager’s house was referred to, and overlooked the entire Newman and Company plantation and the entrance to the harbour. The flagstaff was approximately 9 metres high and was anchored to the rock by six stays. The stays were connected to six small iron ringbolts in the rock, which are still there today.
Circa 1892, Miss Elizabeth Holman, daughter of a Newman and Company plantation manager, reported that the Company would fly the Union Jack flag from this site when British navy ships entered the harbour. The Newman and Company blue and white checkered house flag was also flown from the flagstaff whenever a Newman and Company merchant vessel arrived in Harbour Breton. The practice was the same when vessels departed the harbour.
Newman’s Flagpole Rock has cultural value as it was an old courtship site. It was a popular rendezvous site for some of the young girls who were part of the domestic staff at the Big House and was witness to the initiation of some romantic relationships in the community.
Source: Town of Harbour Breton Regular Council Meeting Motion #09-059 August 19, 2009.
All those elements which represent the historical and cultural values of Newman’s Flagpole Rock, including:
-association with Newman and Company;
-iron ringbolts in rock;
-unobstructed view of Newman’s Flagpole Rock from Newman’s Lookout, and;
-location, orientation and dimensions of the rock.
Municipalités de TNL
Municipalities Act
Terre, structure ou édifice patrimonial municipal
Économies en développement
Commerce et affaires
Élément naturel
Approvisionnements en vivres
Site de pêcheries
Heritage Foundation of Newfoundland and Labrador
1 Springdale Street
St. John's, NL A1C 5V5
NL-4530
Beaver Pond Municipal Heritage Site
Harbour Breton, Terre-Neuve et Labrador
Beaver Pond is located along Route 360 at the entrance to the community of Harbour Breton, in an…
Gun Hill Municipal Heritage Site
Gun Hill is a natural promontory that rises to a height of over 150 metres and is located on the…
Hunt's Point Municipal Heritage Site
Located on the north side of Harbour Breton at the base of Gun Hill, Hunt’s Point is a grassy point…
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Linux Made Simple
ASUS Chromebook C202SA - C202SA-YS01
Today we are looking at the ASUS Chromebook C202SA - C202SA-YS01. It has a durable design focused on scholars as it has spill resistance, rubber corners (drop resistance) and a 180-degree hinge.
It comes with a fanless Dual-Core Intel Celeron N3060 CPU, an 11.6 inch, 1366x768, HD anti-glare display, and a non-touch screen. It has 2GB of RAM and a 16GB eMMC SSD.
It has Android Apps (Google Play) and it does Linux Apps (crostini) support and it will receive auto-updates until June 2022.
It weighs 2.2 lbs and its dimensions are 11.6 x 7.9 x 0.9 in inches. The battery has 2 cells, 38Whr Lithium-ion battery, and 10 hours of battery life.
It has a full-sized HDMI port, HD Webcam, 2 USB ports (two USB 3 ports), it has a MicroSD slot and a combo headphone jack.
Connectivity-wise, it comes with an 802.11 b/g/n/ac built-in Wifi Card and Bluetooth 4.2.
Buy it now on amazon.com
This Chromebook is also available with 4GB of ram.
Have a look at our Rolling Chromebook Sales on amazon .com .ca .co.uk and.de! Click Here
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How to enable the Dark Theme on Elementary OS 5.0 Juno
How to install and use Wine 4.0.1 on Zorin 15
How to install Conky Manager 2.4 on Ubuntu 19.04
For Linux Videos With Voice-Overs, look here! https://www.youtube.com/channel/UCKCE4IQsQCDdzxoF6YF
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news, national,
BUPA has apologised for failings that have occurred in three of its central Victorian aged care homes. The private provider's facilities in Bendigo, Echuca and Woodend fell short of a number of standards during audits by the Aged Care Quality and Safety Commission in the past 12 months. The failure to meet those standards was deemed to place the health, safety or wellbeing of service recipients at both the Woodend and Bendigo facilities at serious risk at that point in time. The situation at Bupa Woodend has since improved, with a February audit finding the service complied with all accreditation standards. The serious risk decision was made in October 2018. Bupa Echuca has also become fully compliant with the accreditation standards, having met only 27 of the 44 expected outcomes in March. A serious risk decision was made in relation to Bupa Bendigo in April, after the facility failed to meet three 'expected outcomes' during a March audit. The failed outcomes are not known. Bupa Villages and Aged Care managing director Suzanne Dvorak said the organisation took seriously its responsibility to care for older Australians and was investing millions to make the changes needed. "We apologise for the past failings that have occurred in some of our care homes, including at Echuca, Woodend and Bendigo," Ms Dvorak said. "We have focused on fixing these problems so no resident experiences unsatisfactory care. Some of this will take time but we are already starting to see genuine progress." The three central Victorian facilities were among a number of Bupa care homes, nationwide, that failed to meet standards during audits. "The vast majority of our homes are working well, passing external audits and providing the care residents should expect," Ms Dvorak said. "We are working to improve the quality of care in each and every home we operate, to help ensure that past mistakes don't happen again and to restore confidence in all of our homes." Aged Care Quality and Safety Commissioner Janet Anderson said serious risk was not an ongoing state. "It is a separate statutory decision based on evidence at a point in time," she said. "Where non-compliance is identified, the aged care provider is placed on a timetable for improvement and is monitored closely by the Commission to ensure [a] return to compliance within a required timeframe." Bendigo Advertiser
https://nnimgt-a.akamaihd.net/transform/v1/crop/frm/CCCaSEL78QLqvgEaPeVcbz/f4c921a3-8dcf-465d-8442-db3f08d1b605.jpg/r19_452_8669_5339_w1200_h678_fmax.jpg
Audit failings at three central Victorian Bupa facilities prompt apology
Emma D'Agostino
BUPA has apologised for failings that have occurred in three of its central Victorian aged care homes.
The private provider's facilities in Bendigo, Echuca and Woodend fell short of a number of standards during audits by the Aged Care Quality and Safety Commission in the past 12 months.
The failure to meet those standards was deemed to place the health, safety or wellbeing of service recipients at both the Woodend and Bendigo facilities at serious risk at that point in time.
The situation at Bupa Woodend has since improved, with a February audit finding the service complied with all accreditation standards. The serious risk decision was made in October 2018.
Bupa Echuca has also become fully compliant with the accreditation standards, having met only 27 of the 44 expected outcomes in March.
A serious risk decision was made in relation to Bupa Bendigo in April, after the facility failed to meet three 'expected outcomes' during a March audit. The failed outcomes are not known.
Bupa Villages and Aged Care managing director Suzanne Dvorak said the organisation took seriously its responsibility to care for older Australians and was investing millions to make the changes needed.
"We apologise for the past failings that have occurred in some of our care homes, including at Echuca, Woodend and Bendigo," Ms Dvorak said. "We have focused on fixing these problems so no resident experiences unsatisfactory care. Some of this will take time but we are already starting to see genuine progress."
The three central Victorian facilities were among a number of Bupa care homes, nationwide, that failed to meet standards during audits.
"The vast majority of our homes are working well, passing external audits and providing the care residents should expect," Ms Dvorak said. "We are working to improve the quality of care in each and every home we operate, to help ensure that past mistakes don't happen again and to restore confidence in all of our homes."
Aged Care Quality and Safety Commissioner Janet Anderson said serious risk was not an ongoing state.
"It is a separate statutory decision based on evidence at a point in time," she said.
"Where non-compliance is identified, the aged care provider is placed on a timetable for improvement and is monitored closely by the Commission to ensure [a] return to compliance within a required timeframe."
Bendigo Advertiser
This story Audit failings at central Victorian Bupa facilities prompt apology first appeared on Bendigo Advertiser.
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Mrs. Rita Lockwood Peters Wilkinson
Rita Lockwood Peters Wilkinson
Age 88, was born August 31, 1931, in Ferrum, Virginia, and passed peacefully away on December 26, 2019, in Roanoke, Virginia.
She worked for Dr Pepper in Roanoke, Virginia, for 34 years. She accepted a “temp” job at Kroger in Roanoke and retired from this second career in 2012.
Rita loved learning and was a lifelong student – earning her last degree with her grandchildren in the audience at the commencement ceremony cheering, “Way to go, MeMaw” as she walked across the stage to receive her diploma.
She loved the beach; she loved her coffee; she loved her children and she adored her grandchildren!
She was preceded in death by her parents, Harry Morton Peters and Roosevelt Gusler Peters; two brothers, Wallace Neil Peters and Harry Delano Peters; three sisters, Jean Peters Morgan, Wanda Ellis Peters and Majella Peters; and her husband, James Howard Wilkinson. She is survived by a sister, Yvonne Peters Goldsmith (and her husband, Charles); a brother-in-law, James Howard Morgan; a sister-in-law, Naomi Wilkinson Murray; her son, James William Wilkinson; her daughter, Sue Lockwood Wilkinson Ridder (and her husband, Kevin); three grandchildren and one great grandchild.
Graveside service will be held at the Franklin Memorial Park Cemetery, 21440 Virgil H. Goode Hwy, Rocky Mount, Virginia 24151, on Monday, December 30, at 2:00 pm.
In lieu of flowers, contributions may be made in Rita’s name to the Hollins Road Church of the Brethren or the charity of your choice.
Franklin Memorial Park Cemetery, Rocky Mount, Virginia
Franklin Memorial Park
21440 Virgil H. Goode Highway
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Posted On: 17 Jan 2020 - 12:17pm
By Barbara Myerson Katz
On a morning last winter, I watched as some 150 women lined up in a sunny, high-ceilinged room at the Olmsted off Frankfort Avenue for Louisville Business First’s Bizwomen Mentoring Monday. As in speed dating, every seven minutes a bell signaled participants to rotate, the goal being that mentees would meet potential mentors among more than 40 there, all women representing organizations that included nonprofits, higher education, healthcare, banking, tech startups, retail, law firms and more. (The next Mentoring Monday is slated for Feb. 24.)
As the session came to a close, a young woman who had snagged a slot with Louisville Urban League President and CEO Sadiqa Reynolds said she’d been waiting since the previous year for the chance to talk to her. Reynolds flashed a surprised smile and told the young woman she could have called her any time. Later, Reynolds says to me, “A mentor is a navigator” — someone who helps remove both professional and personal barriers. She says it’s important to have help navigating the workplace, where there’s often no safe place to talk about challenges. “I’m the person they can call at night when everything is going wrong,” she says, then adds, perhaps only slightly kidding,
“I tell them, ‘I want you to be positioned well enough to hire me when I need a job.’”
Christien Russell, 27, was a student at Central High School when a pastor who knew of her interest in law introduced her to Reynolds. Russell ended up shadowing Reynolds, who was then a Jefferson County district judge. Russell, who got her master’s degree in public administration, is pursuing a doctorate in agricultural sciences with a focus on diversity, equity and inclusion, and is currently a special assistant in the USDA Office of the Assistant Secretary for Civil Rights in Washington, D.C. “Growing up in the West End of Louisville, seeing a black person in (Reynolds’) position, I knew I was worthy to be in those positions,” Russell says. “She will give it to you raw, but the intent is for you to be better at the end of the day.”
Leadership Louisville president Cynthia Knapek says mentorships are readily available in Louisville. Her organization, for example, has a 100 Wise Women program, and other groups focusing on mentoring include the Young Professionals Association of Louisville (YPAL) and Greater Louisville Inc. Brown-Forman offers its employees a program called Growing Remarkable and Outstanding Women (GROW). YPAL president Aimee Jewell says to find a great mentor, “You have to figure out what you need from that relationship.”
We talked to a dozen women representing multiple generations and varied careers about wisdom that has been passed down and helped them get where they are — and become who they are — today.
Marie Abrams
Legislative aide to former Kentucky state Sen. David Karem; former national chair, Jewish Council on Public Affairs
Mentors have included late community leaders Betty Jane Fleischaker, Minx Auerbach, Maud Fliegelman, Jane Greenebaum and Louis Cole — all role models during Abrams’ multiple decades as a community volunteer. “The community leaders taught me: Don’t assume someone will say no; ask them. Never undersell a job,” Abrams says. “Never say it’s not a big deal, because if it’s not a big deal, why would you ask them to do it? David Karem (who for decades served as president of Waterfront Development Corp.) taught me that change doesn’t happen right away. You need to look at change as a series of little victories.”
Dana Allen
Senior vice president for marketing and communications, Norton Healthcare; former marketing director at Brown-Forman
“My boss, Russ Cox (Norton Healthcare president and CEO), has told me, ‘Sometimes, you just gotta breathe.’ I’m a little woman who walks fast and hard. I don’t think everything’s a fight, but I do think I work pretty hard. Sometimes you have to just breathe
and relax.”
Kim Baker
President, Kentucky Center for the Arts
Mentors have included the late Holly Salisbury, director of the University of Kentucky Singletary Center for the Arts, where Baker worked while studying arts administration; and Madeline Abramson, the wife of former Mayor Jerry Abramson and past chair of the Kentucky Center for the Arts board of directors. “Holly Salisbury told me to think about the challenges of working in a cultural institution that is a 24/7 career when you also want to have a family,” Baker says. “To make it your career, you need to be prepared for the lines to blur a bit, to integrate it. Madeline Abramson taught me that it’s important to thank people and never underestimate the people who help you do what you need to do — and that when I think about things I need to accomplish, there are people I can lean on to help me.”
Alice Houston
CEO, HJI Supply Chain Solutions in Louisville
Mentors have included her late mother, Helen Kean Johnson, who was a special-education teacher; her aunt, the late Naomi Lattimore, a librarian at what was an all-black public library at 10th and Chestnut streets; another aunt, the late Ivanetta Davis, who was married to the president of Tennessee State University; and the late Louisville Central High School teacher Thelma Lauderdale. They all emphasized and modeled the importance of education. “We were instilled with a tremendous amount of confidence and were told that there were 52 cards in a deck, but (as African-Americans) you were only going to be playing with 26,” Houston recalls. “They convinced you that you could play with those 26 cards and win.”
Dr. Mary Fallat
Professor of surgery, University of Louisville; surgeon-in-chief, Norton Children’s Hospital
“Patricia Numann (founder of the Association of Women Surgeons) got to know my entire family and was able to know that side of me, the part that grew up in Auburn, New York, in a small city with a family that was very close. She was there for me when I had personal challenges and challenges during my career, for potentially life-changing decisions,” Fallat says. She mentions that similarly sage advice came from another mentor, Dr. Toni Ganzel, current dean of the University of Louisville School of Medicine. “She told me to seek the moral high ground when making difficult life decisions,” Fallat says. “This advice actually kept me here in Louisville at a point in time when I had considered looking elsewhere in the country for a job.”
Sharon Darling
Founder and president, National Center for Families Learning (NCFL)
Mentors have included the late First Lady Barbara Bush, with whom Darling connected through Bush’s ongoing interest in adult literacy. “When I would meet with Barbara Bush (including at the White House), at the end of the conversation when I would get up, she’d say, ‘Fluff the pillows when you get up,’” Darling says. “That was a metaphor for how to leave things intact for the next person to come, the next generation. Preserve things. Don’t destroy things in the process.”
Former president, Leadership Louisville; first female sports reporter at the Courier-Journal
A primary mentor was the late Courier-Journal sports editor Earl Cox, who hired a relatively inexperienced Johnson away from the Louisville Associated Press bureau after she covered her first sports press conference at the University of Louisville. “The best advice I ever received was the importance of building relationships in your career. That came from Wilson Wyatt, an iconic Louisville civic leader who also was a special envoy for President John F. Kennedy. He said he used the same people skills defusing an international crisis in Indonesia as he did solving problems walking the streets as Louisville’s mayor,” Johnson says. “He had the ability to listen to people on all sides of a difficult issue, then seek common ground. He never interjected his own opinion first. He also had a genial manner and ready smile that inspired trust and respect. A remarkable combination of style and substance made him a successful leader at home and across the world.”
Jackie Keating
Chief Development Officer, Dare to Care
Dana Allen, Norton Healthcare VP, became an important mentor when Keating was recently married and new to Louisville. “I remember having breakfast with (Allen) on the very first day that I was back to work after maternity leave,” Keating says. “Like many new parents, I was consumed by thoughts of my son while at work, and then consumed by thoughts of work when at home. I looked at her and said, ‘How do I do this?’ She responded, ‘Jackie, your 80 percent is everyone else’s 120 percent. You’re going to be just fine.’ Over time, I’ve concluded that while I don’t believe those percentages to be true, if I keep doing the work with the best I can offer at that given moment, that is enough. Her encouragement allowed me exactly what I needed — a deep breath and some grace.”
Cynthia Knapek
President, Leadership Louisville
An important mentor is Christine Johnson, who preceded Knapek as the head of Leadership Louisville and encouraged her to follow in that position. “When I was a new mom, Chris told me, ‘You can have it all; you just can’t have it all today,’” Knapek says. “I pair that with advice from (former Louisville Business First editor) Carol Timmons, who told me that the secret is ruthless prioritization, in that on any given day there’s one thing that you’re supposed to do really well. On any day you can be the best mom ever, you’ve made home-baked cookies, you’ve brought them into the bake sale. The very next week you have one of those days where you’re a rock star at work, got it all done, got home — and served Frosted Flakes for dinner. And you should celebrate that the thing you prioritized is the thing that you did well.”
Tori Murden McClure
President, Spalding University; first woman to row solo across an ocean (1989); first woman to ski to the geographic South Pole (1999)
Mentors have included the late Louisville Collegiate School history teacher Helen Longley and the late Barry Bingham Jr., civic leader and editor/publisher of the Courier-Journal. She got to know Bingham Jr. as an undergrad at Smith College in Massachusetts. Over many years, they shared more than a thousand pages of correspondence. “Barry recognized in me someone who he would have described as having a fire in the belly,” Murden McClure says. “In my mature years, I realize I was angry at the world (over injustices). If he could help me to navigate the rage, he would set me up to be more productive in the world. One of the things he said was, ‘Nothing worth doing is easy.’ Helen Longley would have said, ‘The difficult takes time; the impossible just takes longer.’”
Attica Scott
State representative and the only African-American woman currently serving in the Kentucky Legislature
Mentors include former Kentucky Rep. Eleanor Jordan, who was the last black woman to serve in the Kentucky Legislature prior to Scott’s election in 2016; Jackie Floyd, community organizer in the Russell neighborhood, who helped bring Scott back to Louisville to work with Kentucky Jobs With Justice; and Pastor Derrick Miles of Greater Friendship Baptist Church in the California neighborhood. From Representative Jordan and Jackie Floyd, Scott says she has learned, “You’re a mom first, whatever your leadership position is. So always remember: Your greatest success is your kids. That informs everything I do. I’m always thinking about what’s best for my kids and the different places in which they navigate — their public schools, their neighborhoods, their jobs. What is going to make a difference in their lives and in the lives of their children and the children after them?”
Sadiqa Reynolds
President and CEO, Louisville Urban League
A primary mentor has been Lexington attorney and University of Kentucky law professor emeritus Carolyn S. Bratt, for whom Reynolds worked while in law school. “It’s one thing when your family tells you you’re smart. Carolyn Bratt gave me a level of confidence that someone who had been in my life all along couldn’t provide. One time, she took me with her to a meeting about a multi-million-dollar negotiation she was working on,” Reynolds recalls. “I had on my traditional navy-blue suit, and I had my briefcase with me, and it’s just the two of us. And the other side, they’ve got like seven people, no diversity in the room, I’m the only person of color. I think the other side were all white men. Carolyn goes out of the room for something, and (one of the men) asks me, ‘Are you her secretary?’ And I said, ‘No, I’m her law clerk.’ Later, Carolyn said, ‘If you had been a man, at the very least he would have suggested that you were something other than a secretary.’ It was the first time in my life that I realized gender was also playing a role in how people looked at me. It helped me see the world as it was being presented.”
Theresa Reno-Weber
President and CEO, Metro United Way
Mentors have included Louisville Mayor Greg Fischer, with whom Reno-Weber worked for several years as Louisville Metro chief of performance and technology; Phoebe Woods, former CFO at Brown-Forman; and Maggie Harlow, CEO of Signarama downtown. Reno-Weber says she’s learned from her mentors that, “You can and should define your own success and follow the things that excite you. Bring your full self to the work — Mayor Fischer would say, ‘Head, heart and hands.’ Don’t worry about it making sense to others as long as it makes sense to you.”
This originally appeared in the January 2020 issue of Louisville Magazine under the headline “How She Got Here.” To subscribe to Louisville Magazine, click here. To find us on newsstands, click here.
Cover photo: Attica Scott (left, by Mickie Winters) and Sadiqa Reynolds (by Jessica Ebelhar).
louisville urban league
Christien Russell
Leadership Louisville
Bizwomen Mentoring Monday
Cynthia Knapek
100 Wise Women
YPAL
Aimee Jewell
Jewish Council on Public Affairs
Betty Jane Fleischaker
Minx Auerbach
Maud Fliegelman
Jane Greenebaum
David Karem
Dana Allen
Russ Cox
Holly Salisbury
Madeline Abramson
Helen Kean Johnson
Naomi Lattimore
Ivanetta Davis
Thelma Lauderdale
Patricia Numann
Earl Cox
Wilson Wyatt
Carol Timmons
Helen Longley
Barry Bingham Jr.
Elanor Jordan
Jackie Floyd
Drrick Miles
Carolyn S. Bratt
Greg Fischer
Phoebe Woods
maggie harlow
Sadiqa Reynolds at the Muhammad Ali Center
A Cambodian New Year’s Celebration in Louisville
Leading Ladies of Louisville: Maggie Harlow, Signarama CEO
Person of the Year: Sadiqa Reynolds
Drinking and Drawing with the Louisville Cartoonist Society
Remembering the Derby City Chop Shop Dog
His Grandfather Died of Cancer After Working for DuPont Chemical. Now He’s in a Movie About It.
Can This Man Rebrand the Ohio River?
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Rain AS
in soccer games
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Image puzzles are common with children, and embody Join-the-Dots and Spot the Distinction where two variations of a picture are shown side by side, and you should spot the difference.
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Apple, The New York Instances, USA Right this moment, Mother and father Magazine and Scholastic, to call just a few, have featured ABCya’s in style instructional games. The Walt Disney Company has a good relationship†with Digital Arts and has no interest in returning to video games, something with which it was by no means capable of show much ability,†CEO Bob Iger said in an earnings call Tuesday.
By taking part in some foreplay games earlier than sex can help to get the both of you into the temper of getting intercourse, which can sometimes result in a scorching passionate sex. Sega launched Dreamcast in 1998 with a built-in modem for online play which pioneered online gaming with consoles, but failed. So, from Battle Royale free-to-performs, like Fortnite, to MMORPGs, like Lord of the Rings Online, the best free games cover a variety of genres and styles.
In the present day, players can place bets proper up until shortly before the 12:55 p.m. mid-day or the 7:57 p.m. evening drawings. Formally labeled as a free trial†on Steam, there is not a lot to distinguish the hero shooter from other free-to-play games available on the market.
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Addicting Games is the biggest supply of the best free on-line games together with humorous games, flash games, arcade games, dress-up games, web games, capturing games, phrase games, RPG games, racing games, and rather more. You may play sophisticated games promptly with the assistance of a rapid Web connection. You may play single player games or play superior massive multiplayer games with other players from all over the world. You possibly can download the sport totally free or run it in your browser utilizing Java, making it rather more handy than most different online function-players of this epic scale.
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Currently: Malaysia (English)
Keppel O&M certified for 3D printing of offshore grade materials.
Manufacturing Marine & Shipping Metals, Fabrication & Components
The additive manufacturing (AM) technology would enable Keppel to print high-value components for offshore products with significantly faster production times and more economically.
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Keppel Offshore & Marine (Keppel O&M), in partnership with Nanyang Technological University, Singapore (NTU Singapore) and the A*STAR (Agency for Science, Technology and Research) Singapore Institute of ManufacturingTechnology (SIMTech) has been awarded the Lloyd’s Register (LR) Certification for its Laser Aided Additive Manufacturing (LAAM) system to produce offshore grade steel. This certification conforms to the American Society of Testing and Materials (ASTM) A131 requirements following an audit and successful mechanical testing.
Mr Aziz Merchant, Executive Director, Keppel Marine & Deepwater Technology, said: “This certification is the first step for us to produce high-value components essential to the offshore and marine structures. Additive manufacturing (AM) or 3D printing as it is more commonly known will speed up production times which in turn can help bring projects to completion much quicker.”
“We are pleased to work with NTU and SIMTech since 2016 on developing AM technology, and the LR certification shows that the components we produce using this method are safe and fit for purpose – something that is paramount to our business.”
Besides reducing project lead times, 3D printing can also alleviate resource constraints, reduce the carbon footprint associated with manufacturing and provide long-term cost savings.
NTU researchers conducted rigorous tests on over 50 specimens of 3D-printed offshore grade steel, checking them on their material yield, tensile, elongation, fatigue and toughness properties. Coupled with an optimised 3D printing process, the material properties of the steel were found to have high standards that exceeded ASTM requirements.
Mr Hussain Quraishi, Senior Consultant in LR’s Singapore Advisory Centre, said: “It’s great to see how AM can bring such positive benefits, not only to the businesses we’re working with, but to their customers too. AM is a highly innovative technique that more and more companies are turning to in their drive to offer high-quality components for use in projects across a wide range of industries.”
LR provides an additively-manufactured part certification service for all industries, from marine class-related parts to oil and gas upstream and downstream. Part certification involves assessing all aspects of a company’s production process, including design, material, facility, post-processing and testing.
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Annual Review 2018/19: reaching new heights for a safer world
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Skip Navigation LinksLake Murray Country > Things to do > Attractions > Purple Martin Phenomenon
Purple Martin Phenomenon
Lunch Island
Attractions , Tours
At night, the Purple Martins take flight! Each summer the skies over Lunch Island on Lake Murray come to life as the Purple Martins arrive for their summer vacation. It is estimated that more than one million birds venture north for the summer and roost on the island, giving spectators a rare look at one of nature's true phenomenons. This sanctuary provides the ideal layover for Purple Martins as they make the long journey south to their winter home in South America. This sanctuary remains the largest roosting site in North America.
The sky gets dark and millions of birds fill the pre-dawn and evening skies each day. Louse Chambers with the Purple Martin Conservation Association best described the experience watching the spectacle. "As it got darker, the birds flew lower, closer and closer to the boats, much to our delight. At all times, we could hear the characteristic roost sound, described as 'hissing steam' or growling. As the darkness increased, circling martins descended on the island, where they covered everything so thickly, it gave a softened appearance to the contours of the vegetation. The impression was that of a thick martin 'frosting' covered everything, like a new heavy snowfall. The routine used by martins to leave the circling flocks, and dive down into the roost, was fascinating to watch. As a group of martins circled low over the island, suddenly many martins, perhaps the whole bottom layer of the circling flock would pour steeply down into the roosting group. Martins left the roost almost as steadily as they arrived, with new little swarms constantly rising up into the sky. It was over a little after 9:00pm."
Time of year? End of June to beginning of August. The number of birds peak in mid-late July.
Time of day? In the evening. The birds funnel in starting about 30-45 minutes before sunset, but will be flying in until dark. From 8:00pm-9:15pm is the best time to be there in mid-July. In the morning, the birds begin leaving the island as soon as there is any light in the sky. Plan to be there from 5:30am-7:00am. It has been recorded that when the birds leave in the morning, it is like an explosion and the local weather radar has said the image is larger than Hurricane Hugo was in 1989
Where? Lunch Island, often referred to as Bomb Island or Doolittle Island.
Where do they go during the day? They disperse to feed, sometimes traveling up to 100 miles away for food.
How to see them? By boat at Lunch Island located in the middle of gorgeous Lake Murray. Boats are available to rent around Lake Murray or personal tours are being offered. See links below for details.
See The Phenomenon
Boat Rentals on Lake Murray
Pontoon Rentals and Tours- Kenny Hardee
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Land Of Basketball.com
Teams, players profiles, awards, stats, records and championships.
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1985-1986 Season Final Standings.
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/ 1985 / 1984 / 1983 / 1982 / 1981 / 1980 / 1979 / 1978 / 1977 / 1976 / 1975 / 1974 / 1973 / 1972 / 1971 / 1970 / 1969 / 1968 / 1967 / 1966 / 1965 / 1964 / 1963 / 1962 / 1961 / 1960 / 1959 / 1958 / 1957 / 1956 / 1955 / 1954 / 1953 / 1952 / 1951 / 1950 / 1949 / 1948 / 1947
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Home > NBA Year by Year > 1986 > Regular Season Standings
< 1984-85
Summary and Awards / Teams
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Brackets / Series / Scores / Leaders /
NBA 1985-86 Regular Season Standings
This page features the complete 1985-1986 NBA season standings, including conference and division ranks, wins, loses, percentage, games behind and teams that qualified for the playoffs
x = teams that made the playoffs are marked with an 'x'
NBA 1985-86 Conference Standings
1 Los Angeles Lakers 62 20 .756 - x
2 Houston Rockets 51 31 .622 11.0 x
3 Denver Nuggets 47 35 .573 15.0 x
4 Dallas Mavericks 44 38 .537 18.0 x
5 Utah Jazz 42 40 .512 20.0 x
6 Portland Trail Blazers 40 42 .488 22.0 x
7 Sacramento Kings 37 45 .451 25.0 x
8 San Antonio Spurs 35 47 .427 27.0 x
9 Phoenix Suns 32 50 .390 30.0
10 Los Angeles Clippers 32 50 .390 30.0
11 Seattle Supersonics 31 51 .378 31.0
12 Golden State Warriors 30 52 .366 32.0
1 Boston Celtics 67 15 .817 - x
2 Milwaukee Bucks 57 25 .695 10.0 x
3 Philadelphia 76ers 54 28 .659 13.0 x
4 Atlanta Hawks 50 32 .610 17.0 x
5 Detroit Pistons 46 36 .561 21.0 x
6 Washington Bullets 39 43 .476 28.0 x
7 New Jersey Nets 39 43 .476 28.0 x
8 Chicago Bulls 30 52 .366 37.0 x
9 Cleveland Cavaliers 29 53 .354 38.0
10 Indiana Pacers 26 56 .317 41.0
11 New York Knicks 23 59 .280 44.0
NBA 1985-86 Division Standings
1 Houston Rockets 51 31 .622 - x
2 Denver Nuggets 47 35 .573 4.0 x
3 Dallas Mavericks 44 38 .537 7.0 x
4 Utah Jazz 42 40 .512 9.0 x
4 Los Angeles Clippers 32 50 .390 30.0
5 Seattle Supersonics 31 51 .378 31.0
6 Golden State Warriors 30 52 .366 32.0
5 New York Knicks 23 59 .280 44.0
1 Milwaukee Bucks 57 25 .695 - x
2 Atlanta Hawks 50 32 .610 7.0 x
6 Indiana Pacers 26 56 .317 31.0
Abbreviations: W = Wins / L = Losses / Pct = Winning Percentage / GB = Games behind
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Land of Basketball is a fan website, for official NBA information visit National Basketball Association's website.
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Category: Stainless Steels
Austenitic stainless steels are the most commonly used grades of stainless steel as they can provide predictable levels of corrosion resistance and excellent mechanical properties. Easily recognised from their non-magnetic properties, the completely austenitic grain structure means that they are extremely formable, readily welded and retain their ductility down to cryogenic temperatures. They can also be used at raised temperatures, as they retain more of their strength in comparison with ferritic alloys. They can be significantly strengthened by cold working, but this work hardening effect also means that machining may need to be undertaken more carefully. Larger section sizes can be strengthened by warm working. As a wholly austenitic structure, heat treatment has no effect.
Good corrosion resistance is imparted by 16-25% Cr additions, but can be significantly improved by further additions. For instance, Alloy 316L benefits from the addition of molybdenum to improve resistance to pitting and crevice corrosion in chloride environments. Alloy 254 contains significant levels nickel, molybdenum and copper to further enhance corrosion resistance in aggressive environments, making it suited to brackish or polluted water contact, or in applications containing halide ions (chloride, bromide, fluoride) where it can be a cost-effective alternative to more expensive nickel and titanium alloys in such environments.
The range of Fermonic® 50 grades (also known as Nitronic® 50 – a trademark of AK Steel Corporation) provide more than double the strength of Alloy 316L for instance, benefiting from controlled nitrogen additions to strengthen the austenitic structure. Higher strength allows section sizes to be reduced, whilst retaining the favourable characteristics of austenitic grades in general. The Fermonic® 60 product (also known as Nitronic® 60 – a trademark of AK Steel Corporation) is more specialised – it has superior galling resistance resulting from additions of manganese and silicon, making it preferable for applications where there is repeated movement/sliding or frequent assembly/disassembly.
Alloy Common Name Related Specifications Tensile Strength Proof Test Elongation
British European United States N/mm2 (ksi) N/mm2 (ksi) (%)
Alloy 316L 1.4404
Fermonic 50 – Annealed (UNS S20910 XM-19) 1.3964
Fermonic 50 – High Strength / Extra High Strength 1.3964
Fermonic 60 ASTM A479/A276
Alloy 254 1.4547
ASTM A479/A473/A240
DIN 1.4404
X2 CrNiMo 17-12-2
JIS SUS316TKA
ASTM MT316L
Nitronic® is a registered trademark owned by AK Steel Corporation. Fermonic® is a registered trademark owned by Langley Alloys Limited.
Alloy 316L:
Alloy 316L is an austenitic stainless steel supplied in the hot worked and annealed condition. The addition of Mo provides the product with much improved corrosion resistance compared with Alloy 304, particularly with respect to pitting and crevice corrosion in chloride environments. Alloy 316L resists atmospheric corrosion, as well as, moderately oxidizing and reducing environments. It also resists corrosion in polluted marine atmospheres. The alloy has excellent resistance to intergranular corrosion in the as-welded condition.
Fermonic 50 – Annealed (UNS S20910 XM-19):
Fermonic® 50 – Annealed is a nitrogen-strengthened austenitic stainless steel which is supplied in the annealed condition. It provides almost double the yield strength of common austenitic stainless steel grades such as Alloy 304 and Alloy 316L, offering the potential to reduce section size and therefore weight and cost. Higher strength can be achieved through cold working. Importantly, it remains fully austenitic – and therefore, fully non-magnetic – even after severe cold-working.
Fermonic 50 – High Strength / Extra High Strength:
Fermonic® 50 – HS/EHS (also known as Nitronic® 50 – a trademark owned by AK Steel Corporation) is a nitrogen-strengthened austenitic stainless steel that can be supplied in the cold worked or warm worked condition. Although very small diameter bars of Fermonic® 50 (<2.25”) can be cold worked to achieve higher strength levels, larger section sizes can only achieve dramatically increased mechanical properties by deforming at raised temperatures. This results in a deformed and partly recrystallised micro structure that is ‘stress free’, achieves high strengths with good ductility and consistent properties through the bar (unlike cold worked material). The superior properties of Fermonic® 50 HS/EHS are available up to 9” diameter bars.
Fermonic 60:
Fermonic® 60 is a fully austenitic alloy supplied in the hot worked and annealed condition. The general corrosion resistance is between that of Alloy 304 and Alloy 316 stainless steel, whereby is it generally better than Alloy 304 in most environments but superior to Alloy 316 with respect to chloride pitting resistance. More significantly, additions of Silicon and Manganese provide superior wear, galling and fretting resistance than many other corrosion resistant alloys making it preferable for applications where there is repeated movement/sliding or frequent assembly/disassembly.
Alloy 254:
Alloy 254 is a high alloy austenitic stainless steel supplied in the hot worked and annealed condition. Significant additions of Mo, Ni and Cu gives this alloy a good resistance to pitting and crevice corrosion, especially in environments containing halide ions e.g. chloride, bromide and fluoride solutions. It is therefore widely used in applications in brackish water, seawater, pulp mill bleach plants and other chloride process streams, where it can be a cost-effective alternative to more expensive nickel and titanium alloys in such environments.
Sanmac 316L (Hollow Bar):
Sanmac® 316L is a molybdenum-alloyed austenitic stainless steel bar with improved machinability. The addition of Mo provides the product with much improved corrosion resistance compared with Alloy 304, particularly with respect to pitting and crevice corrosion in chloride environments. Sanmac 316L resists atmospheric corrosion as well as moderately oxidizing and reducing environments. It also resists corrosion in polluted marine atmospheres. The alloy has excellent resistance to intergranular corrosion in the as-welded condition.
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Dick the Dick Roundup
There are a number of significant Dick Cheney articles on the web now, and I want to link them before they get stale. So, in no particular order and without further ado …
Frank Rich, New York Times, “Dishonest, Reprehensible, Corrupt …”:
If Mr. Bush and Mr. Cheney believe they were truthful in the run-up to the war, it’s easy for them to make their case. Instead of falsely claiming that they’ve been exonerated by two commissions that looked into prewar intelligence – neither of which addressed possible White House misuse and mischaracterization of that intelligence – they should just release the rest of the President’s Daily Briefs and other prewar documents that are now trickling out. Instead, incriminatingly enough, they are fighting the release of any such information, including unclassified documents found in post-invasion Iraq requested from the Pentagon by the pro-war, neocon Weekly Standard. As Scott Shane reported in The New York Times last month, Vietnam documents are now off limits, too: the National Security Agency won’t make public a 2001 historical report on how American officials distorted intelligence in 1964 about the Gulf of Tonkin incident for fear it might “prompt uncomfortable comparisons†between the games White Houses played then and now to gin up wars.
SOONER or later – probably sooner, given the accelerating pace of recent revelations – this embarrassing information will leak out anyway. But the administration’s deliberate efforts to suppress or ignore intelligence that contradicted its Iraq crusade are only part of the prewar story. There were other shadowy stations on the disinformation assembly line. Among them were the Policy Counterterrorism Evaluation Group, a two-man Pentagon operation specifically created to cherry-pick intelligence for Mr. Cheney’s apocalyptic Iraqi scenarios, and the White House Iraq Group (WHIG), in which Karl Rove, Karen Hughes and the Cheney hands Lewis Libby and Mary Matalin, among others, plotted to mainline this propaganda into the veins of the press and public. These murky aspects of the narrative – like the role played by a private P.R. contractor, the Rendon Group, examined by James Bamford in the current Rolling Stone – have yet to be recounted in full.
No debate about the past, of course, can undo the mess that the administration made in Iraq. But the past remains important because it is a road map to both the present and the future. Leaders who dissembled then are still doing so. Indeed, they do so even in the same speeches in which they vehemently deny having misled us then – witness Mr. Bush’s false claims about what prewar intelligence was seen by Congress and Mr. Cheney’s effort last Monday to again conflate the terrorists of 9/11 with those “making a stand in Iraq.†(Maj. Gen. Douglas Lute, director of operations for Centcom, says the Iraqi insurgency is 90 percent homegrown.) These days Mr. Bush and Mr. Cheney routinely exaggerate the readiness of Iraqi troops, much as they once inflated Saddam’s W.M.D.’s.
It says a lot, I think, that most of these posts talk more about the vice president than about the president. For all his bluster and strutting, IMO Bush is essentially a passive president who allows others to make decisions for him and does only what he assumes he is expected to do.
Sidney Blumenthal, Salon, “The Long March of Dick Cheney”:
The hallmark of the Dick Cheney administration is its illegitimacy. Its essential method is bypassing established lines of authority; its goal is the concentration of unaccountable presidential power. When it matters, the regular operations of the CIA, Defense Department and State Department have been sidelined.
Richard Nixon is the model, but with modifications. In the Nixon administration, the president was the prime mover, present at the creation of his own options, attentive to detail, and conscious of their consequences. In the Cheney administration, the president is volatile but passive, firm but malleable, presiding but absent. Once his complicity has been arranged, a closely held “cabal” — as Lawrence Wilkerson, once chief of staff to former Secretary of State Colin Powell, calls it — wields control.
Michael Kinsley, Slate, “Fight or Flight?”:
We are now very close to that point of general agreement in the Iraq war. Do you believe that if Bush, Cheney, and company could turn back the clock, they would do this again? And now, thanks to Rep. John Murtha, it is permissible to say, or at least to ask, “Why not just get out now? Or at least soon, on a fixed schedule?” There are arguments against this—some good, some bad—but the worst is the one delivered by Cheney and others with their most withering scorn. It is the argument that it is wrong to tell American soldiers risking their lives in a foreign desert that they are fighting for a mistake.
Michael Hirsh, Newsweek, “Isolating Cheney”:
NEWSWEEK has learned that only Cheney’s office rejected language clarifying the rules for military tribunals at Guantanamo Bay. Those regulations were hashed out last week by Sen. Lindsey Graham, Attorney General Alberto Gonzales and White House Counsel Harriet Miers, with crucial support from arch-conservative Sen. Jon Kyl of Arizona and Democrat Carl Levin of Michigan. “Gonzales wanted to fix it, the White House was friendly to the idea, the Defense Department was on the fence and the vice president’s office was off in a ditch,†said a Republican official on Capitol Hill who was involved in the negotiations.
Jacob Weisberg, Slate, “The Misleaders”:
Here’s what we do know already, without a congressional inquiry: Members of the Bush Administration were dishonest with the public and with Congress about prewar intelligence. We’ve known this for some time—see, for example, the comprehensive and damning story Barton Gellman and Walter Pincus wrote in the Washington Post in August 2003 (“Depiction of Threat Outgrew Supporting Evidence“). Over the past two years, several incidents of executive-branch dishonesty in the run-up to the war have turned into subscandals of their own: the aluminum tubes that Iraq used for missiles and not gas centrifuges, the yellowcake uranium that Saddam didn’t try to buy from Niger, the mobile biological warfare laboratories that turned out to be hydrogen generators for balloons, the al-Qaida chemical warfare training that was based on a false confession, the meeting with Mohamed Atta that didn’t happen in Prague.
If you examine these and other pillars of the administration’s case for invading Iraq, a clear pattern emerges. Bush officials first put clear pressure on the intelligence community to support their assumptions that Saddam was developing WMD and cooperating with al-Qaida. Nonetheless, significant contrary evidence emerged. Bush hawks then overlooked, suppressed, or willfully ignored whatever cut against their views. In public, they depicted unsettled questions as dead certainties. Then, when they were caught out and proven wrong, they resisted the obvious and refused to correct the record. Finally, when their positions became utterly untenable, they claimed that they were misinformed or not told. Call this behavior what you will, but you can’t describe it as either “honest” or “truthful.”
Mark Silva and Stephen Hedges, Chicago Tribune, “As Cheney stands up, his polling goes down”:
In another example of Cheney’s tough posture, Wilkerson said Cheney and Rumsfeld encouraged Bush to wield unbridled power in the wake of the Sept. 11 terrorist attacks.
“The vice president, the secretary of defense and others … made this tremendous pitch for new world: `Mr. President, in this new world you are all-powerful. There is no power of the Congress that can stop you. You are commander in chief of the armed forces. You have the perfect right in this new world, where we are seeking security against this new and unprecedented threat, to make any rules or regulations you want.'”
This entry was posted in Dick Cheney by maha. Bookmark the permalink.
1 thought on “Dick the Dick Roundup”
Swami on November 27, 2005 at 8:34 pm said:
the National Security Agency won’t make public a 2001 historical report on how American officials distorted intelligence in 1964 about the Gulf of Tonkin incident for fear it might “prompt uncomfortable comparisons
Speaking of uncomfortable comparisons…That’s why they sneak the dead servicemen back into the country under the cover of darkness. Yeah, we really honor our fallen soldiers with the hero’s welcome at midnight.
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High School Students Could Win a Truck With Near Perfect Attendance
@manitobapost
DAUPHIN — Students at a Manitoba high school have a major incentive to show up for class — they could start their summer driving a truck.
Kids with 90 per cent attendance at Dauphin Regional Comprehensive Secondary School are entered in a draw to win the vehicle at the end of the year.
Teacher Patty Goodine says the incentive program started four years ago and there’s been a 20 per cent increase in attendance.
She says local dealerships provide the grand prize.
There are other reasons to show up for class.
Students with perfect attendance in a week are eligible to win iPads, GoPro cameras or gift certificates.
Goodine says those are more attainable and help students work towards the big final draw.
"Our motto is if you are here we can build relationships," she said.
"The idea behind this is to help guide the students and help them become successful and graduate and to open doors to many options for their future."
Grade 10 student Zach Zurba took home a 2004 Chevy Avalanche truck on Friday.
Five other students maintained perfect attendance all year — one for three years in a row — and they each ended their school year with gift packages donated by the community and valued at more than $1,000.
"Our main goal is to get students here so we can be a support to them," Goodine said.
"And I think everybody recognizes, obviously our sponsors recognize, the importance of attendance because they are willing and eager to give."
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ForefrontMayo Clinic Cancer Center's Online Magazine
StoriesArchivesAbout ForefrontEmail newsletterPrint editionSubscribe
Volume 1, Issue 2, 2012
Robert B. Diasio, M.D.
It is my pleasure to share the fall issue of our new quarterly email newsletter, a companion to Forefront, the annual print magazine of Mayo Clinic Cancer Center, and a showcase for our latest cancer research.
As I reviewed the stories for this issue, I was reminded of a quote from a 1938 talk that Dr. William J. Mayo, one of Mayo Clinic's founders, gave at the opening of a new building on the campus in Rochester, Minn.: "We think of the truth as something that is invariable, but add a new circumstance and we have a new truth." Dr. Mayo's quote is an appropriate theme for the stories featured in this issue of Forefront, as they highlight research that has created new circumstances and new truths that improve our understanding of cancer and our ability to detect and treat it.
These new circumstances include a treatment for multiple myeloma that has fewer side effects, research that could eventually lead to an accurate gene-based test for prostate cancer, a new intestinal probe that can simply and effectively detect pancreatic cancer, and a new alternative medicine approach to treating cancer-related fatigue.
At Mayo Clinic Cancer Center, we strive to turn new circumstances and discoveries like these into truths and treatments that will reduce the burden of cancer on patients and their loved ones. I invite you to follow our progress by subscribing to Forefront.
Director, Mayo Clinic Cancer Center
William J. and Charles H. Mayo Professor
NCI renews Lymphoma SPORE grant at Mayo Clinic, University of Iowa
Newly discovered biomarkers detect prostate cancer and predict recurrence
PBA-10007593
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Inducible nitric oxide synthase promotes insulin resistance in obesity
Amy Karon
MDedge News
View on the News
A new understanding of insulin resistance
Understanding the mechanisms for how obesity affects cellular pathways is critical for identifying therapeutic targets to prevent its adverse consequences. The current study by Qian et al. identifies acquired lysosome dysfunction as a core cellular event that predisposes to insulin resistance in obesity. Lysosomes are degradative organelles that orchestrate cellular metabolism to facilitate homeostasis and confer stress resistance. Through a well-designed series of experiments conducted in a mouse model of diet-induced obesity, the authors demonstrate localization of inducible nitric oxide synthase (iNOS) to lysosomes in the livers of obese animals. This triggers excess local nitric oxide (NO) generation which leads to excessive nitrosylation of lysosomal proteins. A direct consequence of the resultant lysosome dysfunction is impaired autophagy, which is a critical cellular pathway for clearing away damaged organelles and proteins and generating energy under nutrient stress. Their studies also implicate lysosomal NO generation in suppressing the activity of transcription factor EB (TFEB), a master regulator of autophagy and lysosome biogenesis. Remarkably, genetic ablation of iNOS prevents the lysosome dysfunction and autophagy impairment, to attenuate obesity-induced insulin resistance.
Future studies will be required to assess the mechanisms for iNOS localization to the lysosomes and its interplay with the mammalian target of rapamycin (mTOR) signaling pathway in the face of sustained nutrient excess.
Dr. Abhinav Diwan
These findings will spur future investigation into the role for lysosomal NO generation in a broad range of conditions that the obesity epidemic predisposes sufferers to, namely diabetes, fatty liver disease, atherosclerosis, and heart failure. Most importantly, these observations kindle the hope that therapies to stimulate the autophagy-lysosome pathway, which are being hotly pursued in the context of neurodegenerative and cardiovascular pathologies, may also be translated to prevent the adverse consequences of obesity.
Abhinav Diwan, MD, is an associate professor of medicine, cell biology, and physiology at Washington University and associate division chief of cardiology at the John Cochran VA Medical Center, both in St. Louis. He has no conflicts.
FROM CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
Obesity promotes the localization of inducible nitric oxide synthase (iNOS) in hepatic lysosomes, leading to a cascade of downstream effects that include excess lysosomal nitric oxide production, reduced hepatic autophagy, and insulin resistance, investigators reported.
“It is well known that in the context of obesity, chronic inflammation and lysosome dysfunction coexist in the liver,” wrote Qingwen Qian, PhD, of the University of Iowa in Iowa City and associates in Cellular and Molecular Gastroenterology and Hepatology. “Our studies suggest that lysosomal iNOS-mediated nitric oxide signaling disrupts hepatic lysosomal function, contributing to obesity-associated defective hepatic autophagy and insulin resistance.” They noted that the findings could hasten the development of new treatments for metabolic diseases.
Lysosomes recycle autophagocytosed intracellular and extracellular material, which is crucial to maintain several types of homeostasis within the liver. Each hepatocyte has about 250 lysosomes, which help regulate nutrient sensing, glycogen metabolism, cholesterol trafficking, and viral defense.
Activation of iNOS is a hallmark of inflammation, and iNOS levels are known to be elevated in the livers of patients with hepatitis C, alcoholic cirrhosis, and alpha 1-anti-trypsin disorder, the researchers wrote. “At the cellular level, iNOS produces pathological nitric oxide [NO], which triggers downstream effects, such as aberrant S-nitrosylation. These downstream effects can disrupt the function of organelles such as the mitochondria and the endoplasmic reticulum.”
Studies indicate that pathologic NO impairs lysosomal function in neurodegenerative diseases, cardiovascular disease, nonalcoholic fatty liver disease, and kidney disease, Dr. Qian and associates noted. But it was unclear whether NO in hepatocytes was generated by local iNOS or localized to lysosomes.
The researchers therefore studied cell cultures of primary murine hepatocytes by measuring their lysosomal activity, autophagy levels, and NO levels. They also studied a murine model of diet-induced obesity in which 60% of calories were from fat. They performed glucose tolerance tests by means of intraperitoneal glucose injections and studied the effects of insulin infusion. Finally, they performed immunohistology, immunohistochemistry, electron microscopy, and measurements of nitrosylated proteins and lysosomal arginine in frozen liver sections from the mice. Lysosomal arginine is required to catalyze NO production in the setting of inflammation as observed in obesity. In fact, concomitant stimulation of lysosomal arginine transport and activation of mTOR (an enzyme which tightly regulates transcription factor EB) was sufficient to stimulate lysosomal NO production in hepatocytes even in the absence of an inflammatory stimulus; pointing to a central role for these processes.
The researchers found that a NO scavenger diminished lysosomal NO production, while overexpression of both mTOR and a lysomal arginine transporter upregulated lysosomal NO production and suppressed autophagy. In mice with diet-induced obesity, deleting iNOS also improved nitrosative stress in hepatic lysosomes, promoted lysosomal biogenesis by activating transcription factor EB, enhanced lysosomal function and autophagy, and improved hepatic insulin sensitivity. Improved insulin sensitivity diminished, however, when the researchers suppressed transcription factor EB or autophagy-related 7 (Atg7).
Usually, iNOS is primarily expressed in hepatic Kupffer cells, but obesity increases the expression of iNOS in hepatocytes, which promotes hepatic insulin resistance and inflammation, the researchers commented. Unpublished data indicate that deleting iNOS initially protects against obesity-linked fatty liver steatosis and insulin resistance, but that these benefits weaken over time. “Nevertheless, our data showed that liver-specific iNOS suppression has a protective role,” they wrote. “Specifically, we showed that iNOS inactivates transcription factor EB, and that suppression of transcription factor EB and Atg7 diminishes the improved hepatic insulin sensitivity by iNOS deletion.” Transcription factor EB both regulates autophagy and is a “key player in lipid metabolism,” they added. It remains unclear whether the metabolic effects of iNOS solely relate to autophagy, they noted.
Funders included the American Heart Association, American Diabetes Association, and National Institutes of Health. The researchers reported having no conflicts of interest.
SOURCE: Qingwen Qian, et al. Cell Molec Gastroenterol Hepatol. 2019;8(1):95-110.
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The directors of Kick Cancer to the Curb of Mille Lacs County met with Julie Lang, who started the Kanabec County organization that inspired theirs.
From left to right: James Gerads, Roxanne Gerads, President Tracy Vanderpoel, Julie Lang, her husband Steven Lang, Dean Hjort, Annette Alley and Bob Alley.
Mille Lacs County Kicks Cancer to the Curb
by Evan Orbeck
Evan Orbeck
Cancer is an ever present disease of current age.
On their website, the American Cancer Society estimates that there will be 1.7 million new cancer cases diagnosed in 2019. Inspired by work being done in another nearby county, a new organization has formed in Mille Lacs County this year to help relieve the hardship cancer inflicts locally.
President Tracy Vanderpoel explained that a Kick Cancer to the Curb organization had first been founded by her friend, Julie Lang, in Kanabec County. While Vanderpoel’s organization was not officially affiliated with Lang’s, it was inspired by and aimed to emulate Lang’s organization. Kick Cancer to the Curb of Mille Lacs County officially began its work in May of this year, Vanderpoel said, after six months of work getting the organization set up. She added that the organization has been fully recognized as a non-profit.
Vanderpoel said that she works as a hospice nurse at Fairview Hospital in Princeton. Her work has involved taking care of many individuals with cancer. “You just see what they and their families go through,” she added. Vanderpoel has been diagnosed with cancer herself, and her perspective on battling the disease was not just professional, but personal as well. “Our whole goal is to help people who are battling this disease,” she said. Kick Cancer to the Curb of Mille Lacs County provides financial assistance for the medical costs of cancer on a six-month basis. If a patient was still undergoing treatment after six months, they could qualify again. Vanderpoel outlined two simple requirements for this assistance: you have to be a resident of Mille Lacs County and undergoing treatment or hospice for cancer. “It has no bearing on what their financial background is,” she added. To get support, Vanderpoel said, individuals have to fill out a form, available at the Kick Cancer to the Curb of Mille Lacs County website or by contacting the organization. Vanderpoel said forms are also available at the Princeton and Onamia hospitals as well the other clinics throughout Mille Lacs County. A doctor or nurse will need to sign the form to verify a patient is undergoing treatment and the organization would send a check once this form was reviewed. If an applicant met the above requirements, Vanderpoel said, their application would be approved. She also noted that the application process was entirely confidential. “The unique thing about our organization,” Vanderpoel noted, “is the money stays here in Mille Lacs County … When you are donating to our organization, it’s helping your friend, your neighbor, your loved one. It’s so unique because most organizations aren’t like that.” She elaborated that the money will not be going toward administrative fees, and no one in the organization will be making a salary off donations. Nearly 100% of the money will be going toward county residents, she stated.
Fundraising events are currently in the works, Vanderpoel said, and will be starting either during the fall or around the beginning of winter. The organization’s goal is to have events throughout the whole of the county, in Princeton and Milaca as well as the county’s northern cities, such as Isle and Onamia. If anyone wants to make a direct donation to the organization, Vanderpoel said, checks can be mailed to Kick Cancer to the Curb of Mille Lacs County: P.O. Box 132, Milaca, MN, 56353.
Volunteer work is also needed and Vanderpoel encouraged anyone interested in doing so to reach out to the organization. She noted that volunteers interested in organizing efforts for the northern Mille Lacs community were particularly needed.
Vanderpoel said Lang’s goal was to see a Kick Cancer to Curb form in every county in the state, and through the work she is doing, Vanderpoel is contributing to that mission.
Kick Cancer to the Curb of Mille Lacs County can be reached through their website: kickcancertothecurbmillelacsco.com. They are on Facebook, www.facebook.com/kickCancertotheCurbofMilleLacsCo/ and can be reached by phone, 320-260-1869, or email, kickcancerofmillelacs@gmail.com.
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Metso global website News 2017 Metso's Financial Statements Review January 1 - December 31, 2016
Stock Exchange release February 3, 2017 09:00:00 AM CET
Metso's Financial Statements Review January 1 - December 31, 2016
Metso Corporation, Stock exchange release, February 3, 2017 at 09:00 a.m. EET
Metso will arrange a results audiocast today at 1:00 p.m. EET. The audiocast is viewable at www.metso.com/latestreports. A simultaneous conference call will be arranged, allowing participants to ask questions. A recording and a transcript of the event will be available on the same page on February 6, 2017, at the latest.
This is a summary of Metso's January-December 2016 Financial Statements Review. The complete report is attached to this release as a pdf-file and is also available at www.metso.com/latestreports.
Figures in brackets refer to the corresponding period in 2015, unless otherwise stated.
Fourth-quarter 2016 in brief
· Demand for aggregates equipment improved and demand for mining services stabilized during the quarter.
· Orders received totaled EUR 672 million (EUR 758 million), of which EUR 442 million
(EUR 441 million) were services orders.
· Sales totaled EUR 676 million (EUR 754 million), of which services accounted for EUR 442 million (EUR 481 million).
· Adjusted EBITA totaled EUR 64 million, or 9.4 percent of sales (EUR 91 million, 12.0%). The lower EBITA resulted from lower volumes, project overrun costs and warranty costs in Minerals, as well as from a negative impact related to non-operative items in the Group head office.
Full-year 2016 in brief
· Market environment was challenging.
· Orders received totaled EUR 2,724 million (EUR 2,965 million), of which EUR 1,741 million
(EUR 1,879 million) were services orders.
· Orders clearly exceeded sales and consequently the year-end backlog grew 4 percent
· Sales totaled EUR 2,586 million (EUR 2,923 million), of which services accounted for
EUR 1,703 million (EUR 1,840 million).
· Adjusted EBITA totaled EUR 274 million, or 10.6 percent of sales (EUR 356 million, 12.2%).
· Operating profit totaled EUR 227 million, or 8.8 percent of sales (EUR 555 million, 18.7%), and was negatively impacted by net adjustment items resulting from continued restructuring to adapt the structure and footprint to market conditions.
· Strong free cash flow of EUR 339 million (EUR 341 million), resulting from a release of net working capital.
· The Board of Directors proposes a dividend of EUR 1.05 per share (EUR 1.05)
Outlook for 2017
Metso's overall trading conditions are expected to be slightly better than in 2016. Demand for our products and services in 2017 is expected to develop as follows:
· Remain weak for mining equipment and satisfactory for mining services.
· Improve to good for aggregates equipment and services (previously: satisfactory both for equipment and services)
· Remain satisfactory for Flow Control products related to customers' new investments and satisfactory for Flow Control services, with some positive signs seen in the oil & gas markets in the beginning of the year.
At the end of December 2016, our backlog for 2017 totaled approximately EUR 1.2 billion. In the current market conditions, we continue to expect some postponements to planned delivery timetables. Negative adjustment items from restructuring programs initiated in 2016 are expected to be EUR 10-15 million. Capital expenditure excluding acquisitions is expected to increase compared to 2016 but remain below depreciation and amortization.
President and CEO Matti Kähkönen:
Last year proved to be challenging, especially in the mining and oil & gas markets. The demand for mining equipment was more or less in line with 2015, and the demand for services seemed to stabilize in the last quarter. In aggregates we saw positive development as the demand for equipment strengthened in the US, Northern Europe, and India. The biggest change in 2016 was seen in the oil & gas market, where customers became clearly more cautious about downstream investments during the second half of the year.
On a positive note, our annual orders exceeded sales, and the Group's profitability was satisfactory, despite lower sales in both Minerals and Flow Control. In addition, we reported a strong free cash flow and our balance sheet strengthened significantly. Though I am pleased with the cost-efficiency measures we have carried out so far, we will continue to look after our costs and take measures where necessary also going forward.
We proceeded with many internal actions during the year. The digitalization of both our offering and business models is under way and good progress was made during 2016. We implemented a new operating model in the Minerals equipment business and made notable progress with the standardization of our products and projects for a smoother sales-to-delivery process. We also continued to broaden our distribution network and add new distributors in both Flow Control and Aggregates.
Our market outlook for 2017 illustrates some optimism, as we expect the market situation to be slightly better compared to 2016. The most prominent improvement, which started already last year, seems to be taking place in the aggregates business. In the mining and oil & gas markets the year has started in a relatively positive way, but it is still too early to announce a meaningful recovery.
EUR million Q4/2016 Q4/2015 Change % 2016 2015* Change %
Orders received 672 758 -11 2,724 2,965 -8
Orders received by the services business 442 441 0 1,741 1,879 -7
% of orders received 66 58 64 63
Order backlog at the end of the year 1,320 1,268 4
Sales 676 754 -10 2,586 2,923 -12
Sales of the services business 442 481 -8 1,703 1,840 -7
% of sales 65 64 66 63
Earnings before interest, tax and amortization (EBITA), adjusted 64 91 -30 274 356 -23
% of sales 9.4 12.0 10.6 12.2
Personnel at the end of the year 11,542 12,619 -9
* The Process Automation Systems (PAS) business was divested on April 1, 2015. The full-year 2015 comparison numbers for Metso Group and Flow Control including the PAS business are presented in the tables section.
IFRS figures
EUR million Q4/2016 Q4/2015 Change % 2016 2015 Change %
Operating profit 44 67 -34 227 555* -59
% of sales 6.6 8.9 8.8 18.7*
Earnings per share, EUR 0.17 0.35 -53 0.87 2.95* -71
Free cash flow 97 59 64 339 341 -1
Return on capital employed (ROCE)
before taxes, % 10.4 25.7*
Equity-to-asset ratio
at the end of the year, % 48.0 48.3
Net gearing at the end of the year, % -1.8 10.6
* Including a capital gain on the disposal of PAS
Metso is a world leading industrial company serving the mining, aggregates, recycling, oil, gas, pulp, paper and process industries. We help our customers improve their operational efficiency, reduce risks and increase profitability by using our unique knowledge, experienced people and innovative solutions to build new, sustainable ways of growing together.
Our products range from mining and aggregates processing equipment and systems to industrial valves and controls. Our customers are supported by a broad scope of services and a global network of over 80 service centers and about 6,000 services professionals. Metso has an uncompromising attitude towards safety.
Metso is listed on the NASDAQ OMX Helsinki, Finland, and had net sales of about EUR 2.6 billion in 2016. Metso employs over 11,000 persons in more than 50 countries. Expect results.
www.metso.com, twitter.com/metsogroup
Matti Kähkönen, President and CEO, Metso Corporation, tel. +358 20 484 3000
Eeva Sipilä, CFO, Metso Corporation, tel. +358 20 484 3010
Juha Rouhiainen, VP, Investor Relations, Metso Corporation, tel. +358 20 484 3253
Eeva Sipilä
Juha Rouhiainen
NASDAQ OMX Helsinki Ltd
Conference call details
Conference call participants are requested to dial in five minutes before the scheduled time on:
other countries: +44 (0)330 336 9105
The confirmation code for joining the conference call is 6501163.
A recording of the event is available at www.metso.com/latestreports at the earliest after the event has finished and a transcript of the event will be available.
Metso Financial Statements Review 2016 Download
Metso in Twitter
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Law Office of Michael A. Johnson
Effective and Affordable Solutions
Tucson Child Support Attorney
Prominent Family Law Firm In Arizona
The most serious disputes in a divorce involve either children or money. In these situations, it is best to have an experienced attorney on your side guiding you through the process of establishing a support order.
Tucson Child Support Lawyer
In Arizona, child support is determined by the Arizona Child Support Guidelines. The guidelines take into consideration the following:
Gross monthly income of the parents
Medical insurance premiums
Day care/after-school costs
Extraordinary costs (needs of a disabled child or educational costs)
It is best to have an experienced lawyer guide you through this process. A less experienced attorney, or individuals who attempt to proceed without representation, might miss factors or miscalculate variables eventually costing them thousands of dollars.
As opposed to the calculation of child support, the determination of spousal support is at the discretion of the judge. Some of the factors the court considers include:
Accurate income of both parties through subpoenaed earnings statements
Labor market analysis of his or her earning capability
Ability to work or retrain for a new career
Contributions or sacrifices made during the marriage
Length of the marriage
Ability of a spouse to pay spousal maintenance
Over the course of a marriage, if one spouse supported another's education or military relocation, this can translate into monetary value. In these situations, it is possible to argue that the supportive spouse did not have the opportunity to develop a career. Many times, we can get rehabilitative support to finance a spouse's return to school to prepare for a new career. To support this goal, Michael will investigate financial records to thoroughly prepare. It is important to get an accurate picture of a family's finances to ensure a fair outcome.
If you have questions regarding child support, contact the Law Office of Michael A. Johnson, P.C., by calling 520-834-8932 or toll-free at 866-930-1744 or completing the contact form on this website. We offer a free initial phone consultation and affordable rates for legal services. Our office is conveniently located off I-10, across the street from the Pima County Superior Courthouse.
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Why test your gut microbiome?
Author: Dr Alena Pribyl and Rebecca Morehouse
17 September 2019 Education
There's growing interest and excitement around the idea of microbiome testing. Thanks to developments in medical technology over the past decade, gut microbiome testing is easy, efficient, highly detailed, and far more accessible than ever before.
In fact, today you can access world-leading insights into the unique microbial community in your gut without ever leaving the comfort of your own home.
However, despite the progress, questions still remain for many people as the technology and conversations surrounding microbiome testing continue to evolve.
“Although it may be easy to test my gut microbiome, why should I? What is the benefit? What sort of information will I be able to discover? Is it worth it?”
While the detailed answers to these questions will vary from person to person, there are some general and compelling reasons for testing your gut microbiome.
Understanding your gut microbiome can provide insights into your wider health and wellbeing.
There are strong links between your gut microbiome and your health and wellbeing. The microbial community in your gut can perform a wide range of metabolic functions, from digesting fibre and protein, to producing thousands of substances that can interact with our immune, metabolic and nervous systems, all the way to transforming the medicines we take.
By testing your gut microbiome, you can learn more about the functions of your own gut microbiome and check that it is helping to keep you healthy and not contributing to making you sick. Using a metagenomic gut microbiome test, you will learn:
Your microbial diversity level
Access highly detailed information about the diversity of microorganisms inhabiting your gut.
Your potential to breakdown nutrients
Discover the potential of your gut microbiome to breakdown macronutrients such as, fibre, protein, simple sugars and fats.
Your potential to produce substances associated with health
Uncover the gene potential of your gut microbiome to produce substances linked to health, such as folate.
Obtain a comprehensive list of the microbial species present
Whether it’s a well known species or newly discovered, you will get a full list of the different bacteria and archaea present in your gut.
Receive tailored guidance from a Microbiome Coach
Gain a deeper understanding of your Insight™ report and discuss your personalised shopping list of food suggestions with a qualified health professional.
Interested to see the potential of your microbiome to breakdown nutrients and produce beneficial substances? Learn more about Microba Insight™.
Although we are only at the tip of the iceberg in discovering the numerous ways our gut microbiome can influence our health, there is already a compelling amount of evidence to suggest gut health is closely linked with the following health areas:
Research has revealed an interplay between the gut microbiome, our metabolic system, and metabolic disorders such as insulin resistance, type 2 diabetes and obesity. Studies have indicated that the gut microbiome in people with metabolic disorders have a reduced ability to produce beneficial substances derived from bacterial fibre digestion such as the short chain fatty acid butyrate1–3 and indolepropionic acid4,5, and an increased ability to produce branched chain amino acids1,3 and the pro-inflammatory substances lipopolysaccharides3,6,7 and trimethylamine-n-oxide (TMAO)8. Human trials have successfully used diet intervention (fibre) to modify the gut microbiome in type 2 diabetes patients, improving blood-glucose regulation9. Research has also demonstrated that the type 2 diabetes drug, Metformin, works through beneficially modifying the gut microbiome10,11.
Mental conditions such as anxiety and depression have been linked to the gut microbiome12,13. Exactly how the gut microbiome may be influencing anxiety and depression is still being investigated. Thus far we know that some gut bacteria can produce or consume neurotransmitters such as GABA, norepinephrine and dopamine and that some bacterial substances can increase the production of serotonin in the gut14,15. However, the effects of bacterially produced neurotransmitters in humans have not been well studied yet. This is an area to keep watching!
The connection between the gut microbiome and cardiovascular diseases is becoming increasingly strong16–19. Cardiovascular conditions such as hypertension and atherosclerosis have been associated with decreased gut bacteria diversity16, decreased gene potential to produce the beneficial short chain fatty acid butyrate17, and increased potential to produce the pro-inflammatory substances trimethylamine-n-oxide16,17,20 and lipopolysaccharides16.
Crohn’s disease and ulcerative colitis are among the first diseases to be linked to the gut microbiome and among the best studied. Common patterns observed in people with IBD include decreased bacterial diversity21–23, decreased gene potential to produce the beneficial short chain fatty acids butyrate and acetate22–25, decreased potential to break down fibre23, and an increased potential to produce lipopolysaccharides22,23. Researchers are currently investigating if targeting the gut microbiome could help prevent and treat IBD.
A new area scientists are investigating is how exercise may impact the gut microbiome, and conversely, if the gut microbiome can influence athletic performance. Thus far, small scale studies have shown that regular exercise can increase the production of beneficial short chain fatty acids by the gut microbiome26,27. And recently, it was discovered that marathon runners have a higher abundance of a specific bacterial species that can convert lactic acid into the beneficial short chain fatty acid, propionate, which helps prevent drops in blood sugar levels28.
The influence of the gut microbiome on our health is a rapidly developing area and new connections are continuously being uncovered. To find out more, take a look at the latest scientific literature.
While the research continues to develop and change, so does your gut microbiome.
Like all ecosystems, your microbiome is in a constant state of change. However, once you have a snapshot of your baseline, you can make evidence-based decisions to maintain or promote a positive balance over time.
Your microbiome can be influenced by numerous factors. The most influential factor is what you eat, however other lifestyle factors such as stress, medications, exercise, age, sleep and your environment can also influence your gut microbiome. This means that changes to any of these circumstances may shift your gut microbiome.
In general, studies have observed that people maintain a set of “core” species29, but the abundance of those species will shift with changes to the listed lifestyle factors30,31. With gut microbiome testing, you can closely monitor the impact of any changes you may make to your lifestyle.
When you understand your microbial community, you can:
Take positive steps to reinforce existing, ‘positive’ bacteria
With the information in a gut microbiome report, you can make informed decisions to promote a positive microbial balance in your gut. For example, if your gut microbiome shows a decreased potential to produce beneficial short chain fatty acids, however you have several beneficial species that produce short chain fatty acids at low abundance, you can take steps to change your diet or other lifestyle factors to promote the growth of those beneficial species.
Keep your gut microbiome in balance
You want to make sure your gut microbiome has an even balance of species and does not have a high potential to produce substances that can promote inflammation or are associated with disease states. If your gut microbiome starts to show an overgrowth of a species or a high potential to produce substances associated with poor health (such as lipopolysaccharides or trimethylamine), you can evaluate recent changes to your diet and lifestyle and make tweaks to bring your gut microbiome back into the healthy range.
Interested in establishing a baseline snapshot of your gut microbiome? Or monitoring changes over time? Learn more with Microba Insight™ home testing kit.
You can use your insights for informed conversations with health professionals.
Once you’ve established your initial insights, you can use them with the support of a relevant healthcare provider who is familiar with the role of the gut microbiome in health.
In partnership with the right health professional, a report outlining the balance of your gut microbiome and its potential to produce health-associated substances can be a valuable tool in your overall health care.
Please note, if you have a medical condition or take regular medication, it is important to speak to your medical practitioner(s) before making any significant changes to your diet or lifestyle.
1) Qin, J..
et al. A metagenome-wide association study of gut microbiota in type 2 diabetes..
Nature 490, 55 (2012).
2) Karlsson, F. H..
et al. Gut metagenome in European women with normal, impaired and diabetic glucose control..
3) Pedersen, H. K. .
et al. Human gut microbes impact host serum metabolome and insulin sensitivity..
Nature 535, 376 (2016).
4) de Mello, V. D. .
et al. Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study..
Sci. Rep. 7, 46337 (2017).
5) Tuomainen, M. .
et al. Associations of serum indolepropionic acid, a gut microbiota metabolite, with type 2 diabetes and low-grade inflammation in high-risk individuals..
Nutr. Diabetes 8, 35 (2018).
6) Harte, A. L. et al..
et al. High fat intake leads to acute postprandial exposure to circulating endotoxin in type 2 diabetic subjects. .
Diabetes Care 35, 375–382 (2012).
7) Jayashree, B. et al. .
Increased circulatory levels of lipopolysaccharide (LPS) and zonulin signify novel biomarkers of proinflammation in patients with type 2 diabetes..
Mol. Cell. Biochem. 388, 203–210 (2014).
8) Shan, Z. et al. .
et al. Association between microbiota-dependent metabolite trimethylamine-N-oxide and type 2 diabetes..
Am. J. Clin. Nutr. 106, 888–894 (2017).
9) Zhao, L. .
et al. Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes..
Science 359, 1151 (2018).
10) Sun, L. et al. .
Gut microbiota and intestinal FXR mediate the clinical benefits of metformin..
Nat. Med. 24, 1919–1929 (2018).
11) Wu, H. et al. .
Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug..
Nat. Med. 23, 850 (2017).
12) Valles-Colomer, M. .
et al. The neuroactive potential of the human gut microbiota in quality of life and depression..
Nat. Microbiol. 4, 623–632 (2019).
13) Zheng, P. et al. .
Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host’s metabolism..
Mol. Psychiatry 21, 786 (2016).
14) Strandwitz, P. .
Neurotransmitter modulation by the gut microbiota..
Gut Meets Brain 1693, 128–133 (2018).
15) Yano, J. M. et al. .
Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis..
Cell 161, 264–276 (2015).
16) Yan, Q. .
et al. Alterations of the Gut Microbiome in Hypertension. Front..
Cell. Infect. Microbiol. 7, 381–381 (2017).
17) .Jie, Z. .
et al. The gut microbiome in atherosclerotic cardiovascular disease. .
Nat. Commun. 8, 845 (2017).
18) Liu, H. .
et al. Alterations in the gut microbiome and metabolism with coronary artery disease severity..
Microbiome 7, 68 (2019).
19) Zhernakova, D. V. .
et al. Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome..
Nat. Genet. 50, 1524–1532 (2018).
20) Zhu, W. .
et al. Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk..
21) Franzosa, E. A. .
et al. Gut microbiome structure and metabolic activity in inflammatory bowel disease. .
22) Vich Vila, A. .
et al. Gut microbiota composition and functional changes in inflammatory bowel disease and irritable bowel syndrome..
Sci. Transl. Med. 10, eaap8914 (2018).
23) He, Q. .
et al. Two distinct metacommunities characterize the gut microbiota in Crohn’s disease patients..
GigaScience 6, 1–11 (2017).
24) Laserna-Mendieta, E. J. .
et al. Determinants of Reduced Genetic Capacity for Butyrate Synthesis by the Gut Microbiome in Crohn’s Disease and Ulcerative Colitis..
J. Crohns Colitis 12, 204–216 (2018).
25) Marchesi, J. R. .
et al. Rapid and Noninvasive Metabonomic Characterization of Inflammatory Bowel Disease..
J. Proteome Res. 6, 546–551 (2007).
26) Allen, J. M. .
et al. Exercise Alters Gut Microbiota Composition and Function in Lean and Obese Humans..
Med. Sci. Sports Exerc. 50, (2018).
27) Estaki, M. .
et al. Cardiorespiratory fitness as a predictor of intestinal microbial diversity and distinct metagenomic functions..
28) Scheiman, J. .
et al. Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism..
29) Mehta, R. S. .
et al. Stability of the human faecal microbiome in a cohort of adult men. .
30) Johnson, A. J. .
et al. Daily Sampling Reveals Personalized Diet-Microbiome Associations in Humans. .
Cell Host Microbe 25, 789-802.e5 (2019).
31) Spor, A., Koren, O. & Ley, R. .
Unravelling the effects of the environment and host genotype on the gut microbiome..
Nat. Rev. Microbiol. 9, 279 (2011). 
Dr Alena Pribyl
Alena is a senior scientist at Microba with a passion for science outreach and communication. Alena's work at the University of Queensland developing the science content to present metagenomic gut microbiome profiles later became the basis for Microba’s Insight Report.
Follow them:
Important functions of the gut microbiome
Inner workings of the gut microbiome: What can be measured?
The effect of antibiotics on your gut microbiome
Read more on related content
By: Dr Alena Pribyl
Jan 2019 Education
Dec 2018 Education
Nov 2018 Education
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Holiday Sickness Training
Regular MASS Trainer, Terry Wilson, can deliver Holiday Sickness Training to demystify the issues and give your fee earners the confidence and skills to take on holiday illness claims
I wonder how many firms have recently been approached by claims management companies offering to provide holiday sickness claims in volume. Certainly from my own understanding and experience there are many genuine cases out there and not enough law firms who are equipped to handle them.
In an ever changing marketplace, many PI firms are now considering diversifying their practices into this area, however, there aren’t that many fee earners who have had experience in this field and are somewhat nervous at this new area of law. The ones that have experience are being snapped up in the market.
Handling these claims, however, is not as complicated or daunting at you may think, particularly when the claims arise from package tour holidays as these are covered by the Package Travel, Package Holidays & Package Tours Regulations 1992 (PTR). Holiday sickness claims arise in contract law with a reliance on various consumer legislation as well as utilising the PTR. The PTR imposes UK standards on the defendant, and where the illness has arisen as a result of a package tour holiday in a foreign country you can claim against the organiser (usually the tour operator) for breach of contract in England and Wales. This avoids the procedural difficulties in litigating in foreign jurisdictions where limitation periods and quantum can sometimes differ.
Historically people accepted getting sick on holiday as par for the course but they are now becoming increasingly aware that it is not acceptable to have their holiday ruined by sickness. The fact is that there are many genuine claimants out there who have had a very unpleasant and sometimes serious illness, had their holiday totally spoilt and have lost money as a result of a breach of standards at a foreign hotel which the tour operator is responsible for dealing with under the PTR. Very often the whole family or party can be affected.
Claimants are entitled to claim for various heads of loss, including:
Loss of Bargain/Diminution (the monetary difference between that paid and that received)
Loss of Enjoyment/Disappointment (larger amounts of compensation are awarded for special occasions such as weddings and themed holidays)
Pecuniary Loss
Legal costs are dealt with on a standards basis.
It has been much highlighted in the press over the last few weeks that there are unscrupulous dealings and practices going around concerning some of these claims, and due diligence has to be carried to ensure that these cases are received from MOJ registered companies and are genuine.
I have been involved in the training for holiday sickness claims for the past six months and, as a MASS Trainer, I am working with MASS Training to deliver a very practical, interactive and fun course which will demystify the issues and give fee earners the confidence and skills to take on these holiday illness claims occurring in foreign countries arising out of package holidays.
Courses can be delivered in house to your PI fee earners in groups, or individually on our external courses.
If you are interested in diversifying into this new area of practice please contact Jenny Braunton for more details.
Category: Legal Training Articles
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Muslims Who Stand Up To Mullah's Are No 'Islamophobes'
https://www.meforum.org/58017/muslims-stand-up-mullahs
On Sunday March 17, Hassan Sajwani, an active Twitterati in the United Arab Emirates (UAE) quoted a warning his country's foreign minister Sheikh Abdullah bin Zayed Al-Nahyan had delivered to Europe at the "Tweeps Forum" in Saudi Arabia in 2017.
The UAE foreign minister had cautioned Europe about the rise of Islamic extremists within the continent: "There will come a day when we see far more radicals, extremists and terrorists coming from Europe because of (a) lack of decision-making, and [European politicians} trying to be politically correct."
Sajwani's tweet recollecting the UAE minister's 2017 warning turned out to be quite prophetic. The very next day, on Monday, Turkish-born gunman Gokmen Tanis brought the Dutch city of Utrecht to a halt when he fired on a tram (streetcar) killing three people and injuring three others.Dutch prosecutors investigating the attack say, "So far a terrorist motive is being seriously taken into account. Among other things a letter found in the getaway car and the nature of the facts give rise to that," a statement said (in Dutch), without detailing the contents of the letter.
The Utrecht killing of non-Muslims by a Turkish terror suspect cannot be seen outside the recent massacre of Muslims inside two New Zealand mosques by a white nationalist and earlier massacres carried out against Christians inside and outside churches in The Philippines and Nigeria as well as in Pakistan, Syria, Iraq and Egypt.
While the world gave 24/7 coverage to the Christchurch mosque massacre and white folks rightfully denounced one of their own sons, to embrace their Muslim citizens, there was almost no coverage of the Muslim massacre of Christians in Nigeria just a few days earlier on March 4.
Similarly, on Jan. 27, Muslim jihadis bombed a Catholic church in Jolo, Philippines, killing 20 Christians, yet this attack barely caused a ripple. No weeping politicians, no candlelit vigils and no public demonstration by Muslims in Canada denouncing the jihadi terrorists the way whites denounced a white nationalist.
In fact, Islamists in Europe and North America used the outpouring of goodwill towards Muslims to target Muslim critics of Islamism. Death threats called for eliminating me, my friend Maajid Nawaz in U.K., Imam Muhammad Tawhidi in Australia and scores of secular Muslims were targeted.
These attacks angered Ensaf Haider, the Canadian wife of Saudi prisoner of conscience Raif Badawi. She tweeted: "Don't be fooled by Pro-Sharia Islamists in North America. They may want u to believe they r saddened by the #NewZealandMosqueAttacks, but fact is they cant disguise the triumphant spring in their step. Now, they'll milk sympathy and play victim while pushing their Islamist agenda."
As a 2017 report tracking "violent Islamist extremism" found, jihadi terrorism has resulted in the deaths of 84,000 people. There was a total of 7,841 attacks – an average of 21 per day – in 48 countries.
These figures should alarm Prime Minister Justin Trudeau, Opposition leader Andrew Scheer and the NDP's Jagmeet Singh, but all three parroted the Islamist agenda of legitimizing the most regressive segment of Muslims in Canada while abandoning Muslims who have stood up against Sharia and the doctrine of Armed Jihad.
Which begs the question: Why do Christians have the right to laugh at a Ricky Gervais take on God and Jesus, but we Muslims dare not criticize the 17-times-a-day deriding of Christians and Jews that takes place in our mosques across the world?
Just as Martin Luther was no Christianphobe when he stood up to the Roman Catholic Church, Muslims who stand up to Mullahs are no "Islamophobes."
Tarek Fatah, a founder of the Muslim Canadian Congress and columnist at the Toronto Sun, is a Robert J. and Abby B. Levine Fellow at the Middle East Forum.
Related Topics: Moderate Muslims, Terrorism | Tarek Fatah receive the latest by email: subscribe to the free mef mailing list
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Americanisms
As an American, sometimes it's tough to know which commonly-used words and phrases are particular to America, and sound strange in other parts of the world. There was a fascinating round-up of "Americanisms" on this BBC blog the other day, and I wanted to share a few here. Some I find surprising -- what, you guys don't say that? -- and others irritate me as much as the Brits.
• I hear more and more people pronouncing the letter Z as "zee". Not happy about it! - Ross, London
Can't help you there, Ross. "Zed" sounds just as bizarre to our ears.
• "I could care less" instead of "I couldn't care less" has to be the worst. Opposite meaning of what they're trying to say. - Jonathan, Birmingham
I could care more, Jonathan. A lot more.
• My favourite one was where Americans claimed their family were "Scotch-Irish." This of course it totally inaccurate, as even if it were possible, it would be "Scots" not "Scotch", which as I pointed out is a drink. - James, Somerset
What about the phrase "Scot free" -- should that be "Scots free?" (As a whiskey aficionado, I prefer Scotch free. FOR free, that is. HEH.)
• "I got it for free" is a pet hate. You got it "free" not "for free." You don't get something cheap and say you got it "for cheap" do you? - Mark Jones, Plymouth
Damn, now they're picking on me. I have, in fact, heard people say they got something "for cheap." Not very often, mind you. While we're on the subject, "pet hate" is a really strange saying that we don't use here in America. It conjures visions of you taking your hate for walks, buying it organic food, letting it sleep at the foot of your bed. Getting a little too cozy with your hate, you are.
• Surely the most irritating is: "You do the Math." Math? It's MATHS. - Michael Zealey, London
OK, I am REALLY not on board for this one. My position on the matter is this: if you're going to shorten a word -- like, say, mathematics -- you don't get to use the first four letters and then cherry-pick the last letter, in some linguistic approximation of FRANKENSTEIN'S MONSTER. Furthermore, if it bothers you that much, Michael, perhaps we Americans will just start saying "Mathematic" and leave off that pesky S. What's plural about it? We don't say "I'm going to sciences class." SHEESH.
OK, time for our readers to weigh in. I'm getting too emotional here.
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Terriers 1-1 at Western Canada Cup
Portage Terriers’ record is now 1-1 at the Sun Life Financial Western Canada Cup.
Despite a spirited third period, Terriers lost 2-1 to Chilliwack Chiefs Monday night in Penticton. Terriers are off Tuesday, going back on the ice Wednesday against Brooks Bandits.
“We tried to generate some offence but their goaltender made some plays and he was there,” Terriers’ GM/Head Coach Blake Spiller told CFRY-Radio.
“We definitely know we can play here. We made a few mistakes and they cost us. I was happy with the way we played overall. Obviously, we were right there, but couldn’t score that tying goal. It was one of those games which was disappointing, but we have to keep battling.”
“We’ve been here a few times and can keep going. We’ll relax on Tuesday and get back to work on Wednesday; another tough game against a top team. Once again we’ll be ready.”
Despite the loss, Terriers are still very much alive to qualify for one of four playoff spots in the WCC. The MJHL champions have three points in total, tied with Penticton and Chilliwack. Brooks Bandits (AJHL) lead the field with five points, while Battlefords North Stars have a single point.
The WCC playoffs take place on the weekend; two teams from the WCC will move on to the RBC Cup.
James McIsaac scored the lone goal for the Terriers. Chase Brakel was named Portage’s player of the game.
Photo credit: Heather Jordan
Previous PostTerriers Open WCC with a WinNext PostTerriers’ Leipsic nominated for CJHL Award
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MNN.com > Tech > Transportation
Taxi! New York explores plug-in cabs
Mayor Bloomberg wants an all-green fleet — like San Francisco — but that effort has been stymied by a lawsuit. So the 6 Nissan Leaf taxis introduced on Earth Day are a pilot program, but that might lead to greater things ahead.
Jim Motavalli
April 22, 2013, 5:24 p.m.
Mayor Michael Bloomberg arrives at Rockefeller Plaza in a Nissan Leaf electric cab, one of six headed for the city's streets. (Photo: Nissan)
It’s Earth Day, and for Mayor Michael Bloomberg of New York City that meant slipping quietly into Rockefeller Plaza in Midtown Manhattan in a Nissan Leaf, one of six ultra-quiet electric cars that the city will be putting on the road soon.
Joe Castelli, Nissan’s vice president of commercial and fleet vehicles, told me in New York that the Leafs were provided to the city at no cost. Clearly, Nissan appreciates Bloomberg’s love of electric taxis, though actually making them happen beyond the pilot program could prove difficult. Some New York taxi drivers don’t like electrics, because they’ll somehow have to fit charging sessions into their day. And when they’re not driving, they’re not getting paid.
It has to be said that Bloomberg seems very earnest about electric cars. He’s not only buying plenty of electric fleet vehicles, but also installing 480-volt fast charging (for the taxis and the public), and creating regulations that will ensure 20 percent of all new parking spaces are pre-wired for charging. In his State of the City speech in February, Bloomberg said the parking regulation would result in “up to 10,000 parking spots for electric vehicles over the next seven years.”
One of the two fast chargers in Manhattan will be at the Seward Park Coop on the Lower East Side, and is open to the public. The second will be at the Con Edison Building on Irving Place, and accessible only by the taxis. That’s critical, because there can’t be a lot of waiting around if this experiment is going to be at all successful. The media sure got excited about the new Leaf taxis (see below).
Bloomberg also deserves credit for introducing a lot of hybrid taxis (Nissan Altimas, Ford Escapes, Toyota Prius and Camry) into the fleet, but his plan to require gas-electric cabs was stymied by a lawsuit from the powerful Metropolitan Taxicab Board of Trade. The MTBT argued that only the feds can establish fuel efficiency standards, and that hybrids aren’t safe (whatever that means). The result for New Yorkers is a Taxi of Tomorrow, the Nissan NV200, which is conventionally powered, though an all-electric version is coming.
Although big fleets of Leaf taxis won’t happen in New York, the electric e-NV200 would make sense — if it could possibly happen. At the New York Auto Show early this year, Nissan’s Andy Palmer said the NV200 will be available to the city in both hybrid and battery electric versions, though there’s no timetable on U.S. versions. Nissan said the e-NV200 will be built in Barcelona, Spain, beginning in fiscal 2013. Under the skin the NV200 is virtually identical to the Leaf, so the charging issues aren’t significantly different. But the compact van will be much more accommodating to taxi passengers.
Paul Gillespie, the former head of the taxi commission in hybrid-loving San Francisco, thinks the New York Leaf experiment is a cynical greenwashing ploy. “I think the real reason for this PR effort is to generate dozens of media stories about how ‘green’ the Taxi and Limousine Commission (TLC) is, thus diverting attention away from what is actually being proposed,” he wrote in an email. “On the one hand, the TLC is poised to give an exclusive, monopoly 10-year contract to a gas-powered cargo van and make hybrid taxis illegal, while the PR machine is touting a small handful of Leafs, which have failed as taxis elsewhere and caused an unneeded backlash against EVs in general.”
Gillespie points to the California Clean Cab Partnership he helped found as a better alternative. San Francisco’s taxi fleet is now completely converted to hybrid and compressed natural gas cabs, he said. “Los Angeles is approaching 50 percent, well ahead of schedule, and San Diego has 122 Prius Vs in the fleet and growing rapidly. Sacramento and San Jose and Silicon Valley taxi fleets are next in line.”
Related on MNN: I left my hybrid taxi in San Francisco
Jim Motavalli ( @jmotavalli ) writes about cars, technology and the environmental world to anyone curious enough to ask.
Related topics: Electric Cars, Electric Vehicles, Emissions, Energy Policy
Mayor Mike Bloomberg wants an all-green fleet -- like that of San Francisco -- but that effort has been stymied by a lawsuit.
When is store-bought better than homemade?
For this stray dog, there's no place like Subway
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Curt Covington
Mary Ledman
Tom Bailey
Anna-LIsa Laca
Jim Dickrell
Paul Neiffer
Robin Schmahl
Read Milk Magazine
The Three Truths of Climate Change
| By: Dairy Talk
As I walked toward a seminar on dairy’s role in climate change at World Dairy Expo this past October, I overheard one farmer say to another: “The climate is always changing.” They both chuckled dismissively and went on to other Expo attractions.
Earlier that same week, just an hour or so north, farm fields were deluged with another four inches of rain. Grassed waterways looked like streams as the runoff poured from fields. Few farmers along the freeway from Minneapolis to Madison had even begun to cut corn silage. Most of these fields weren’t planted until late May or early June because of another wet, late spring. Fields were no where near ready to chop, and muddy soil conditions would have prevented it anyway.
There is no denying climate change is real. Frank Mitloehner, an air quality specialist and an advocate for animal agriculture at the University of California-Davis, gave a compelling presentation on climate change and the dairy industry’s role in it at Expo. In a nutshell, Mitloehner made three points. You could call them three truths:
Climate change is real.
Dairy plays a role, but it is not what activists say it is.
It is your responsibility to tell dairy’s story.
Climate change is real. In 1750, based on ice cores and other measures, scientists estimate the carbon dioxide (CO₂) concentration in the atmosphere was 280 part per million (ppm). By 2000, that concentration had climbed to about 370 ppm, with CO₂ concentrations starting to spike drastically upward in the 1950s following the rapid industrialization of world economies after World War II. That trend has not stopped—or even slowed.
As a result, global temperatures are rising, the atmosphere contains more moisture, and storms are becoming more frequent and more violent. Five-hundred- and one-thousand-year rain events and storms are occurring several times each decade.
Dairy plays a role. Dairy farming does play a role in this, though it’s far from what activists say it is. The U.S. Environmental Protection Agency (EPA) estimates all of agriculture contributes 9% to U.S. greenhouse gas emissions (GHGs). Animal agriculture contributes 3.9%; dairy about 2%. Transportation, electricity generation and industry produce about 80% of U.S. GHGs, most of which come from CO₂ production.
Dairy’s GHG contribution comes mainly from methane emissions. Though methane is a powerful green house gas, methane from cattle only survives about 10 years in the atmosphere. It is converted back to CO₂, through a process called photochemical oxidation, which is then used by plants for growth. “Dairy is not adding additional carbon to the atmosphere because the amount produced by cows equals the amount destroyed through hydroxylation,” he says. In other words, as long as you don’t add more cows, you don’t add more GHGs to the atmosphere.
The other point is that the more efficient cows are in converting feed to milk, the lower the GHG footprint. North American cows produce about a pound of CO₂ equivalent for every pound of milk they produce. Globally, the average is about 2.1 lb of CO₂ equivalent per pound of milk. In sub-Sahara Africa, the ratio is 7.3:1. “Critics of animal agriculture use these global numbers and apply it to the United States,” says Mitloehner.
Tell dairy’s story. Since 1950, when GHGs started to spike globally, the U.S. dairy industry has reduced the number of dairy cows by 16 million and yet is producing 60% more milk. “We have decreased our carbon footprint by two-thirds over the past 70 years,” says Mitloehner. “Isn’t that an achievement you should brag about?”
Mitloehner says farmers can no longer walk away from the climate debate. “You can’t complain no one is telling your story,” he says. “This is your legacy. You have a responsibility to tell your story.”
To arm yourself with facts and talking points, listen to Mitloehner’s presentation here: https://worlddairyexpo.com/pages/2019-Expo-Seminar-Videos.php
For a shorter tutorial on dairy’s GHG cycle, listen here: https://www.milkbusiness.com/article/difference-between-cows-and-cars-ghg-emissions
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Why Strong Employment Growth Shouldn’t Translate into Higher Canadian Mortgage Rates (For Now)
Last week we received the Canadian employment data for October, which was better than expected.
Our economy added 35,300 new jobs last month and that was more than double the consensus forecast of 15,000 new jobs. The Loonie surged higher on the news and so did Government of Canada (GoC) bond yields as investors upped their bets that the Bank of Canada (BoC) would raise its policy rate once again in early 2018.
While this upside beat was a welcome surprise, our strong employment data in October stand in contrast to other recent data. For example, last week we also learned that our GDP growth fell by 0.1% in August on a month-over-month basis, after coming in at 0% in July, and our export sales revenue fell by 0.3% month-over-month in September. Our export sales have now dropped for four straight months by a total of 1.1% since hitting a record high in May as the headwind from the lofty Loonie continues to buffet our hard-won momentum in that sector.
Therein lies the challenge for the BoC.
When the Loonie hovered in the 75-cent range versus the Greenback in the second half of 2016 and into the early part of 2017, it gave our exports a boost that culminated in eye-watering second-quarter 2017 GDP growth of 4.5%. (Nowadays developed economies consider anything north of 2% GDP growth to be exciting.)
Around that time, the BoC became concerned about the risk of rising inflationary pressures and decided to raise its policy rate by a total of 0.50% this past summer. The Loonie soared, our export volumes tanked, and our GDP growth stalled out before shifting to outright decline in August.
When the Bank met two weeks ago, it adopted a more dovish stance and said that it was now much more “preoccupied with the downside risks to inflation". The Loonie sold off and one assumes that this currency depreciation will help boost our exports over time … but only over time. And there’s the rub.
The BoC plays the long game much more so than the currency traders, bond-market investors and market pundits who react to every new data point. While strong employment growth is a good sign for our economy, BoC Governor Poloz recently said that he believes that our economy is in a “sweet spot”, where expanding output capacity gives it room for non-inflationary growth over the next six to twelve months.
U.S Federal Chair Janet Yellen recently estimated that average wage rises would need to be in the 3% to 4% range over a sustained period before wage costs would meaningfully impact overall inflation, so in that context, while our rate of average wage growth is accelerating, it should still have plenty of room to run before it causes meaningful inflation.
Here are the specific highlights from our latest employment data:
Our economy added 35,300 new jobs last month. All of that growth came from full-time jobs, which increased by 88,000 (offset by a loss of 53,000 part-time jobs), and that’s on top of the 112,000 new full-time jobs that were created in September.
Our unemployment rate rose from 6.2% to 6.3% last month but only because more Canadians came off the sidelines and re-entered the labour market. As a result, our participation rate, which measures the percentage of working-age Canadians who are either employed or actively looking for work, increased from 65.6% to 65.7%. Interestingly, our participation rate still hovers well below its longer-term average level (see chart below). When BoC Governor Poloz talks about our economy having room for non-inflationary growth, that is in large part because there are plenty of working-age Canadians still sitting on the sidelines. As our economic prospects improve, it is expected that many of those people will rejoin the work force, adding to our output capacity and delaying the onset of wage-cost inflation.
Average wages in Canada rose by another 0.3% in September and have now increased by 2.4% on a year-over-year basis, marking a sharp turnaround from earlier this year. By comparison, our average wages were only growing by 0.5% year-over-year in April. While this pick-up in average wages is encouraging, it coincided with a rise in the demand for our exports which recently dissipated, so one wonders how sustainable our current momentum in average wages will be going forward. Also, minimum-wage increases in three of our four most populated provinces are also putting some upward pressure on average wages over the short term, but the BoC would be expected to “look through” this because its impact on inflation will only be temporary.
We also received the latest U.S. employment data last week, which showed the job growth came in lower than expected in October. The U.S. economy added 261,000 new jobs versus the consensus forecast of 310,000.
Most of those new U.S. jobs were of the lower-paying variety (with 106,000 of them coming from the leisure and hospitality sector) and not surprisingly, average U.S. wages fell by 0.1% last month. In addition, U.S unemployment dropped from 4.2% to 4.1%, but only because the U.S. participation rate fell from 63.1% to 62.7%.
This weaker-than-expected data was blamed on hurricane-related disruptions, and the consensus is still convinced that the Fed will raise its policy rate by another 0.25% when it meets in December (the futures market is current assigning a 96.7% probability that this will occur).
If the Fed raises as expected, the Loonie should weaken against the Greenback and give a boost to our export sector. While another Fed hike will also give the BoC more room to raise its policy rate if its becomes more concerned about rising inflationary pressures in the months ahead, at this point uncertainty is still the BoC’s watchword, especially with all of the negative talk around the NAFTA negotiations, so that seems unlikely over the near term.
The Bottom Line: Our latest employment report was encouraging but other recent data, such as our GDP and export sales, indicate that our overall economic momentum is now slowing. The BoC should remain cautious against that backdrop, and as such, I don’t expect that our October employment data will have a material impact on our mortgage rates.
David Larock is an independent mortgage broker and industry insider specializing in helping clients purchase, refinance or renew their mortgages. David's posts appear on Mondays on this blog, Move Smartly, and on his own blog, Integrated Mortgage Planners Email Dave
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LiVES†HE†iC: CANCELED!
I'm sad to say that my live internet talk show (?) has been canceled. But per an exclusive agreement with Zuck, I reserve the right to utilize the URL whenever I please, and will probably air some really awesome shit on it so follow it I guess.
What it's like watching a tennis match unfold live on Google.com
I couldn't find a stream so I have been reduced to watching this "live" score via google to see if my boy Paire could break serve in the first set's third game. SPOILER: He did not.
Here's a lil upcoming tennis ball (🎾) wager. Both matches are set to start at the top of the hour (10AM EST), in separate ATP events. The first of which features my boy Paire playing in his home country of France. He is 0-1 against his opponent but that match was a 5-set affair back in 2010. The bottom draw features my boy Seppi, an Italian, trying to go 3/3 head-to-head vs his opponent in a tournament called "Sofia" in Bulgaria. I love betting on weird things in the morning.
find your own "P A T H" then create mysterious diagrams behind you in the form of discarded Skittles©
What it's like watching a tennis match unfold live...
Here's a lil upcoming tennis ball (🎾) wager. Both...
find your own "P A T H" then create mysterious di...
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BLM releases sage grouse plan
News | November 17, 2004
BOISE, Idaho – Federal land managers have released a strategy to boost sage grouse numbers, hoping to bolster the population of America’s second-largest game bird after a 90 percent decline since the early 1900s.
The fate of the sage grouse, found in 11 states, is garnering national attention because its habitat sits atop some of the nation’s richest natural gas fields in Colorado, Montana, Utah and Wyoming.
Developers wanting to drill for gas are closely watching government plans, as are cattlemen, off-road enthusiasts and environmentalists, some of whom dismissed the Bureau of Land Management strategy as a failure.
BLM said its strategy will guide its federal wildlife managers in restoring bird populations and habitat until programs can be developed on the state and local level.
“The importance of working with state wildlife agencies cannot be overemphasized,” BLM Director Kathleen Clarke said in a statement. “We’ll continue to use the best available science and experience-based knowledge to form our management decisions.”
The U.S. Fish and Wildlife Service is still studying whether low bird numbers warrant Endangered Species Act protection. Sage grouse numbers have declined to about 200,000 from more than 2 million a century ago.
Clarke said the BLM’s strategy puts into place “specific, enforceable requirements to protect sagebrush habitat in permits issued for grazing, recreation, mining and oil and gas activities on public land.”
The BLM owns half of U.S. sagebrush habitat, about 57 million acres.
Some western politicians and wildlife managers hailed the BLM strategy as finding a proper balance.
“This is another indication that federal officials, under the leadership of President Bush, fully appreciate the importance of working closely with state and local officials when developing public lands policies,” said Rep. Mike Simpson, R-Idaho.
Terry Crawforth, director of the Nevada Department of Wildlife, said the BLM plan provides general ground rules to make sound land-use decisions to improve habitat.
“We’ve got 70 local-area planning groups making local-area plans and implementing local-area projects for conservation of sagebrush,” Crawforth said. “BLM has been a player all along. This is firming up that commitment to continue the partnership.”
But environmental groups working to restore sagebrush habitat and species that live there said the agency’s plan doesn’t do enough.
Mark Salvo, director of the Sagebrush Sea Campaign in Chandler, Ariz., said the BLM plan fails to create minimum standards for activities that might hurt sage grouse.
“The BLM is under pressure from the current administration to continue to develop these lands for oil and gas exploitation, to maintain current livestock grazing and to maintain open areas for off-road vehicles,” Salvo said.
Salvo said he sees nothing in the BLM strategy released Tuesday that might affect the Fish and Wildlife study of whether the birds should be listed as endangered. Results of that study are due Dec. 29.
The BLM said its plan helps define methods for assessing risks to sage grouse. The strategy identifies things its managers can do that have proven successful in some areas of the West.
For instance, managers might consider practices such as “green-stripping,” or removing old vegetation and replanting native vegetation, along roads leading to oil and gas developments. This has been done in northeastern Utah.
The BLM also encourages efforts such as the work of a group in Idaho’s Shoshone Basin to manage BLM grazing allotments for both livestock forage and sage-grouse habitat. The percentage of grouse habitat there rated as “excellent” rose to 24 percent of the allotment, up from 2 percent.
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Parks in Nevada City
South Yuba River State Park
California’s first river corridor state park takes in 20 miles of the South Yuba River, ranging from the edge of the Tahoe National Forest near Nevada City to Bridgeport on the west. The park includes four historic bridges, miles of hiking trails, and the nation’s only wheelchair-accessible wilderness trail, the Independence Trail.
Empire Mine State Historic Park
The Empire Mine was once California’s richest gold mine. Today, it is a state historic park where visitors can relive the history of the Gold Rush. See the mines, mining equipment and methods used by early miners. Descend into the dark and damp main shaft. Explore the mansion and gardens of the wealthy mine owner.
Malakoff Diggins State Historic Park
Malakoff was California’s most famous hydraulic gold mine. Miners used high pressure streams of water to wash away hillsides in their quest for gold. Hydraulic mining was halted in 1884 because of its environmental consequences but its colorful history lives on at Malakoff.
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Arroyo del Oso Golf Course
7001 Osuna Road NE Albuquerque, NM 87109
Arroyo del Oso isn't necessarily a tough course. Its features — which include large greens, rolling fairways, three water-hole obstacles, and sand traps — meet the needs of intermediate and advanced players The course opened in 1965. A 9-hole addition named "Dam 9" was constructed in 1987, giving Arroyo del Oso its 27 holes. Arroyo del Oso's primary course is 6,545 yards Par 72 for men, and 6,015 yards Par 73 for women. The Dam 9 plays to a Par 36 at 3,300 yards, crossing the Bear Canyon Arroyo three times. In 1981, Golf Digest Magazine rated Arroyo del Oso among the top 50 Municipal Golf Courses in the nation.
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Newport Life Magazine
Life/Food
Baseball fans will eat over 18 million hot dogs at ballparks this year
Well, hot dog. That's a lot of dogs — and sausages.
This year, baseball fans will snack on 18.3 million hot dogs and nearly 4 million sausages at Major League Baseball ballparks, according to a survey by the National Hot Dog and Sausage Council (yes, apparently that exists).
Dodger Stadium in Los Angeles is projected to sell the most hot dogs at a single park, possibly handing over 2.7 million this year. The runner-up, the Chicago Cubs' Wrigley Field, is projected to sell 1.2 million hot dogs.
But you won't find your average gas station hot dog at these ballparks. For baseball season, hot dogs become an event.
The Arizona Diamondbacks have three dogs inspired by Sports Illustrated this year, including the "All Day Breakfast Dog," featuring hash browns, country gravy, cheddar cheese, bacon, fried eggs hot sauce and green onion onto an 18-inch (!) hot dog. Not to be outdone, the Minnesota Twins' have the "Boomstick" at Target Field — a 2-foot-long "beast" covered in chili, nacho cheese, grilled onions and jalapeños.
If you're a baseball or hot dog fan, you can check out the council's MLB Hot Dog & Sausage Guide to see more over-the-top MVPs of baseball season.
Prepare your stomach if you're headed out to seemingly any ballpark this year. Or at least grab a plain hot dog for the principle of the thing.
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EntertainmentCelebrities
Mindy Kaling is pregnant with her first child, report says
Mindy Kaling attends the "Rei Kawakubo/Comme des Garcons: Art Of The In-Between" Costume Institute Gala at Metropolitan Museum of Art in Manhattan on May 1, 2017. Credit: Getty Images / Neilson Barnard
By Frank Lovece Special to Newsday July 17, 2017 7:26 PM
Comedian and memoirist Mindy Kaling, star of Hulu’s “The Mindy Project,” reportedly is expecting her first child.
E! News, citing multiple anonymous sources, said Monday that the Emmy-nominated writer/producer, 38, who is not publicly in a relationship, was pregnant.
No additional details were given, and Kaling, who appears next year in the films “Ocean’s Eight” and “A Wrinkle in Time,” has not commented on social media.
SEE PHOTOS 68 of our favorite celebrity moms
The former “The Office” cast member and producer told Yahoo! Style in September 2015 that, “I think I’ve decided that unlike everything else in my life, I’m going to be fast and loose about kids. I’m going to not actively plan, but if it happens, it would happen,” adding, “I’m not cavalier about who I would have a kid with. But the thing I ask every parent that I really admire, the one comment they all have is that they wish they had kids earlier.”
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By Frank Lovece Special to Newsday
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LI's Amy Schumer talks effects of IVF treatments
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Jonathan Frakes talks 'Star Trek: Picard,' more
Kardashian West pursues criminal justice reform in TV show
'1917' takes top honor at the Producers Guild Awards
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McConnell Lays Out Plan for Trump's Trial
Bloomberg: My Story Would Have Been Different If I'd Been Black
New York Times Endorses 2 Democrats for President
Biden: Sanders Campaign Is Circulating 'Doctored' Video
Tulsi Gabbard Challenged to Push-Up Contest at Event, Wins
'Show Some Decency,' Sully Tells Lara Trump
National Archives: Sorry We Doctored Anti-Trump Photo
Dems, White House Make Their Arguments
Thousands of Women Target World's 'Biggest Bully'
With Virginia Facing Huge Gun Rally, Trump Tweets
Feds Photoshop Pic of Women's March
Politics /
In Prime-Time Speech, Trump Pushes for a Wall
But president does not declare an emergency in order to build the wall
Posted Jan 8, 2019 8:14 PM CST
Updated Jan 8, 2019 8:32 PM CST
In this image from video, President Trump speaks during a televised address from the Oval Office of the White House. (Pool Photo via AP)
(Newser) – President Trump called the situation at the US-Mexico border a "humanitarian crisis, a crisis of the heart and a crisis of the soul" in a national address Tuesday night—but he stopped short of declaring a formal emergency in order to get a border wall built. In his brief speech, the president again called for $5.7 billion to build a wall, which he said would actually be a "steel barrier," reports Politico. In a quick rebuttal, Nancy Pelosi accused Trump of "manufacturing a crisis" at the border, per the AP, and she and Chuck Schumer reiterated that Democrats would not pay for any such barrier. The president, meanwhile, maintained that the wall "would quickly pay for itself," arguing that its cost would "indirectly" be covered by savings from the new trade pact with Mexico.
Trump also said that "our Southern border is a vast pipeline for illegal drugs," and he again asserted that criminals crossing the border were endangering American lives. The impasse over funding for the proposed wall is at the center of the partial government shutdown, now in its 18th day. The president said the government “remains shut down for one reason and one reason only: because Democrats will not fund border security," per the Washington Post. Countered Pelosi: "The fact is: President Trump must stop holding the American people hostage, must stop manufacturing a crisis, and must reopen the government." The White House has been considering the possibility of Trump declaring a national emergency, a controversial move through which he would divert military money and resources to build a barrier without congressional approval. (Read more President Trump stories.)
Next on Newser: R. Kelly Docuseries May Have Triggered Probe
Rhodium45
Jan 9, 2019 4:52 PM CST
It's called a "Presidential address to the people of the nation". Why should other persons get to speak? They aren't presidents!
Arthur Vandelay
Jan 9, 2019 9:40 AM CST
why is ok for Israel to have a wall but not America Chucky Schumer????
ChesterRush
On CNN, contributor Carl Bernstein said: "I think we need to identify the real national emergency in this country and that is the question of whether or not Donald Trump is fit to be the president of the United States." Ahhahahahaghaa ~~ Right. So basically they’re just pissed still because he won the election. Open borders are for the birds.
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North Korea Wants Mike Pompeo Gone from Nuclear Talks, Asks for Someone More 'Mature'
By Callum Paton On 4/18/19 at 5:59 AM EDT
World International Affairs North Korea Mike Pompeo Nuclear talks
North Korea has taken a swipe at U.S. Secretary of State Mike Pompeo, with Pyongyang saying America's most senior diplomat should be removed from nuclear talks and replaced by someone "more careful and mature."
Reuters reported that the message denouncing the role Pompeo has played in the denuclearization talks was made through North Korea's tightly controlled state media. North Korean Foreign Ministry official Kwon Jong Gun also used his statement to make cryptic statements about the relationship between the U.S. and North Korea, via the country's official Korean Central News Agency.
"No one can predict" the outcome on the Korean Peninsula if the United States fails to abandon the "root cause" that led to North Korea's development of nuclear weapons, Kwon said. He did not elaborate further.
A State Department spokesperson told Newsweek via email that officials were aware of the report. "The United States remains ready to engage North Korea in a constructive negotiation," the spokesperson added.
According to the Associated Press, Pyongyang was displeased by Pompeo's comments during a speech at Texas A&M on Monday. The secretary of state told an audience that North Korean leader Kim Jong Un had promised denuclearization during the his first summit with President Donald Trump, last year in Singapore.
U.S. Secretary of State Mike Pompeo speaks at a news conference while President Donald Trump looks on following his second summit with North Korean leader Kim Jong Un, on February 28 in Vietnam. Tuan Mark/Getty Images
Pompeo said the two nations were working to "chart a path forward so we can get there," and, as such, "[Kim] said he wanted it done by the end of the year," Pompeo said. "I'd love to see that done sooner."
In a statement, the Foreign Ministry's American Affairs Department said Pompeo was "talking nonsense," had "misrepresented" the North Korean position and had a "talented skill of fabricating stories."
The broadside from North Korea comes amid a rapid shifting of tensions between Washington and Pyongyang. North Korea's leadership said Thursday that it had test-fired a new "tactical guided weapon," the first such test in nearly half a year.
In a speech last week to North Korea's nominal parliament, Kim said he was still open to a third round of talks on denuclearization if the U.S. was willing to reconsider its stance on sanctions against Pyongyang.
Earlier this year, talks between Kim and Trump in Vietnam ended abruptly after the two sides appeared to hit an impasse on the thorny issue of sanctions. Trump has continued to emphasize the importance of his personal relationship with Kim. In an April tweet, he wrote: "I agree with Kim Jong Un of North Korea that our personal relationship remains very good, perhaps the term excellent would be even more accurate."
However, Trump said last month that he "would be very disappointed if I saw testing." Neither the White House nor the Pentagon has immediately responded to North Korea's claims of fresh tests.
This article has been updated to include a comment from the State Department.
North Korea Wants Mike Pompeo Gone from Nuclear Talks, Asks for Someone More 'Mature' | World
North Korea Test Fires New Tactical Guided Weapon
North Korea Soldier Shot During Escape Not Mad at Guard
North Korea Chooses New 'Head of State' After 20 Years
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futureDARPA working on jam resistant communication will also enable better usage of Wi-fi and other wireless spectrum
September 1, 2016 | Brian Wang |
In a vision shared by innovators, entrepreneurs, and planners in both defense and civilian contexts, the skies of the future will be busy with unmanned aerial vehicles (UAVs). Unseen but central to the realization of this vision is wireless communication …
microscopesUS Navy envisions submarines with drones attaching and detaching like Remoras to sharks
July 15, 2016 | Brian Wang |
The United States Navy would like to develop two key features for its next-generation SSN(X) successor to the Virginia-class attack submarines. One feature would effectively turn the future attack submarine into a underwater mother-ship for unmanned underwater vehicles (UUV) while …
medicineUS Navy revamps larger drone strategy to primarily refuel manned planes flying a combat air patrol around the carrier
July 7, 2016 | Brian Wang |
The US Navy has revamped its large drone strategy. Now midair refueling and spying are in the plan. The primary mission would be so-called “recovery tanking.” This involves refueling planes flying in a fixed orbit around the aircraft carrier. On …
microscopesGoogle Fiber planning big expansion to Los Angeles, Chicago and other cities
Google announced plans to expand Google Fiber to LA and Chicago — the second- and third-largest US cities. Google also is planning to expand to San Jose, San Diego, Phoenix, Portland, Jacksonville and Tampa. Google Fiber starts with a connection …
brainHydrogels developed for controlled release of hepatitis C drug
Researchers at the Institute of Bioengineering and Nanotechnology (IBN) of A*STAR have developed a drug-delivering hydrogel to treat chronic diseases such as hepatitis C, a liver disease that kills around 500,000 people worldwide every year. “The new gel from IBN …
3dSandia use Z Machine to squeeze Deuterium into Metal
June 26, 2015 | Brian Wang |
Scientists in the US (Sandia Labs) and Germany (Max Planck Institute for Chemistry) have successfully transformed liquid deuterium into a metal at pressures rivalling those at the center of our own planet. The discovery is another step along the long …
microscopesProgress to Mine Seawater for Lithium
Researchers at Japan’s Atomic Energy Agency have come up with a new method of processing seawater to extract lithium—an element that plays a key role in advanced batteries for electric vehicles and one that, if current predictions for the EV …
grapheneLow Cost Millimeter Sensors can provide Haptic Feedback for Robotic Surgery
November 7, 2014 | Brian Wang |
Minimally invasive surgery is becoming more popular. A surgeon uses video game like controls to manipulate robotic arms with long tools on them. These surgical robotic systems do not provide haptic feedback. This can result in accidents that cause bleeding …
futureGuardians of the Galaxy will have around a $100 million opening weekend and very good reviews
August 2, 2014 | Brian Wang |
Guardians of the Galaxy is soaring at the Friday box office for a possible $95 million-plus North American debut, far more than expected and marking another sizeable victory for Marvel Studios as it launches a new franchise outside of the …
futureHobbit : Battle of the Five Armies and other Comic-con 2014 Trailers
If you liked this article, please give it a quick review on ycombinator or StumbleUpon. Thanks Brian Wang Brian Wang is a prolific business-oriented writer of emerging and disruptive technologies. He is known for insightful articles that combine business and technical …
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Fasting increases health and lifespan in male mice
Long periods of fasting between meals helped male mice live longer and healthier lives, regardless of the content of their diets.
More studies are needed to confirm these results and understand how different fasting periods may impact health.
Researchers are working to understand how fasting patterns affect health and lifespan. grafvision/iStock/Thinkstock
Studies have suggested potential health benefits from long-term calorie restriction. In long-term calorie restriction, average daily caloric intake is kept below what is typical or habitual, but without malnutrition or deprivation of essential nutrients. Calorie restriction can be achieved through simply eating less overall, or through specific periods of fasting.
One decades-long study in rhesus monkeys found an extension of lifespan with calorie restriction. However, another did not. Differences between those two studies—including the type of food used—made comparisons difficult.
Researchers from NIH’s National Institute on Aging (NIA), led by Dr. Rafael de Cabo, wanted to better understand if the type of food eaten, and when it is eaten, alters how calorie restriction affects the body. They divided almost 300 male mice into two diet groups. One group was given a diet low in sugar and based more on whole foods. The other group's diet was higher in sugar and more processed.
Within these two groups, the researchers divided the mice into three feeding regimens. One had access to a food dispenser at all hours of the day (ad libitum, AL). A calorie restricted (CR) group received 30% less food than the AL group, placed into their cage once a day at the same time. A meal fed, or MF, group was given the same amount of food as the AL mice on average, but were fed only once a day.
The mice were monitored over the course of their natural lives. Mice that died were examined for evidence of disease, including cancer and liver damage. The results were published on September 6, 2018, in Cell Metabolism.
The researchers had expected that mice eating the whole foods-based diet would have a survival advantage when calorie restricted. But this is not what they observed. Diet composition did not affect health and lifespans. However, the periods of fasting did.
Mice in the MF groups quickly learned that they would not have 24-hour access to food and developed the habit of eating quickly. Mice in the CR groups also finished their smaller meals rapidly. Therefore, the mice in these groups had extended periods of time without food.
Compared with mice in the AL groups, mice in the MF groups lived about 11% longer, even though their total food intake and body weights were similar. Mice in the CR group lived about 28% longer. Mice in the CR and MF groups also developed disease later than mice in the AL groups.
“Increasing daily fasting times, without a reduction of calories and regardless of the type of diet consumed, resulted in overall improvements in health and survival in male mice. Perhaps this extended daily fasting period enables repair and maintenance mechanisms [in the body] that would be absent in a continuous exposure to food,” Cabo says.
Studies in female mice, as well as in other animals, are needed to confirm these findings. More work will also be needed to explore how different lengths of fasting impact health. Finally, the impact of fasting on human health may differ in important ways.
Health Effects of a Diet that Mimics Fasting
Intermittent Dietary Restriction May Boost Physical Endurance
Calorie Restriction May Not Extend Life
Calorie Restriction Slows Age-Related Epigenetic Changes
Pathways Underlying the Benefits of Calorie Restriction
Calorie Restriction and Fasting Diets: What Do We Know?
References: Daily Fasting Improves Health and Survival in Male Mice Independent of Diet Composition and Calories. Mitchell SJ, Bernier M, Mattison JA, Aon MA, Kaiser TA, Anson RM, Ikeno Y, Anderson RM, Ingram DK, de Cabo R. Cell Metab. 2018 Aug 24. pii: S1550-4131(18)30512-6. doi: 10.1016/j.cmet.2018.08.011. [Epub ahead of print] PMID:30197301.
Funding: NIH’s National Institute on Aging.
Machine learning predicts risk of aneurysm
Regrowing neurons across scarred spinal tissue
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A Q&A with Dennis Prager: God Will Ask You Why You Didn’t Vote
June 11, 2019 | Jason Yates | CEO
A few weeks ago My Faith Votes sat down with Dennis Prager, the leading conservative radio host, author and co-founder of Prager University. The wide-ranging conversation, which you can view here, touched on the political and cultural divide in America, how the ideology of the Left constitutes a godless religion that has infiltrated society’s core, raising boys in today’s culture and Big Tech’s biased censorship of over 100 PragerU videos.
To me, though, the most important part of our time with Dennis was the few minutes we discussed why some people choose not to vote.
While the percentage changes from election to election, in general about 60% of eligible voters participate in presidential elections and even fewer, roughly 40%, participate in midterm elections. How sad! Even worse, notice those numbers are only based on eligible voters, not the entire population.
Politics in America has gotten so nasty, so discordant and so partisan — the speaker of the House just told her members she hopes to see the president in prison! — it’s not hard to understand why some would choose to stay as far away from the mess as possible.
Yet for people of faith who don’t vote Prager had a quick and stark message: “Shame on them!”
America, he exclaimed, is the most God-centered, free country in the history of the world, founded by people who believed in God. Our motto is even “In God We Trust.” This is why, Prager said, “God will ask you, ‘Why didn’t you vote to sustain it?’”
A religious man himself, Prager continued to note that he believed sitting out elections, “not to care about the world,” rises to the level of sin. “God has told you all he wants from you,” he added, quoting the Old Testament prophet Micah, “pursue justice and loving kindness and walk humbly with your God.”
How can any person faithfully pursue those things yet not vote to impact our nation with the good of our Judeo-Christian values? That’s a good question to consider.
My Faith Votes—is a nonpartisan movement that motivates, equips and activates Christians in America to vote in every election, transforming our communities and influencing our nation with biblical truth. By partnering with national faith leaders, My Faith Votes provides resources to help Christians Pray, Think, and Act to create an America where God is honored in the public square.
Website | www.myfaithvotes.org Twitter | @MyFaithVotes Facebook | My Faith Votes
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Her Prayers
Guadalupe In the World
Guadalupe Church
Guadalupe Barrio >
Montano Park
El Parque del Rio
Guadalupe District
Guadalupe Trail
Guadalupe Street Project
Santa Fe Blog
VIDEO CANDLES
My Guadalupe
Guadalupe Barrio - Santa Fe, New Mexico
As noted on the Santa Fe Watershed Association website:
"The Santa Fe River Park and Trail follows the river almost ten miles from Patrick Smith Park to the new Camino Real Park at the river’s intersection with NM 599. When completed, the trail will be one of three primary urban trail spines along with the Rail Trail and Arroyo Chamisa Trail serving the Santa Fe area. The parkway will provide open space corridors, trails for walking and biking, and a series of parks, as well as a way for bicycle commuters to get to and from downtown safely. Below are listed some the current projects happening along the river.
Santa Fe River Park, known as El Parque del Rio, is a linear park that follows the Santa Fe River as it flows through downtown Santa Fe. A major amenity and historic site within the city, the river park was beset with a series of long-term problems. Progressive down-cutting of the river channel has affected the health and viability of many of the old cottonwoods and other trees along the park. Storm water that had for decades helped support the river environment is now piped and fed directly into the river, increasing erosion and contributing roadway pollutants. The City of Santa Fe is exploring new ways to handle its storm water runoff and has hired Surrounding Studio to help implement new methods. Surrounding’s team, working with City Public Works staff, has developed a variety of methods for directing storm water to support the river environment, including “oxbow” infiltration structures and pipe conveyance intercepts. A unique idea on the project is modeled on historic agricultural acequias to create “storm water acequias” that take road runoff and intercept and reroute it to linear water-absorbing wicks. Through passive infiltration, these storm water acequias will benefit new orchard trees and native cottonwoods along the river.
Other park improvements and irrigation upgrades are being made at Louis Montano Park (near the Boys and Girls Club); West De Vargas Park at Guadalupe Street; and on the north side of the Santa Fe River along Alameda between Galisteo Street and East Palace Avenue.
Alto Street meanders along the south side of the Santa Fe River and connects the Santuario on the corner of Guadalupe Street with Ambrosio Street to the west. A walk through the Louis Montano Park across from the Santa Fe Boys and Girls Club and continuing west towards Saint Francis Street on the dirt road along the river will reveal an extraordinary collection of locally-painted murals by Carlos Cervantes and other regional artists depicting the Spanish, Mexican, Aztec, and Indigenous influences in the history and culture of the region.
The Guadalupe Barrio is roughly outlined as follows:
Guadalupe Street to the east and Saint Francis Street to the west
West Alameda Street to the north and Agua Fria Street to the south
Hello Guadalupe Barrio Neighbors!
If you live or work in the Guadalupe Barrio and have a story, update, special event, or news to share about our neighborhood or its history...or know of a business or service that needs to be included on this website, please let us know! We are gathering information that might be of interest and would love to include more.
ARTISTS and ARTISANS: We are also looking for artists and traditional artisans who work with the image of Guadalupe and can create Guadalupe art installations in our neighborhood and homes. If you or someone you know would like to be added to our upcoming Artists Directory, please send your name, contact info, a brief description of the work you do, AND a link to your website or any online samples. With your permission, we will include you in our upcoming Guadalupe Artists Directory.
DOWNLOAD a Video Candle
© 2013 www.MyGuadalupe.com
PO box 33423, Santa Fe, New Mexico 87501 USA
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Markets in 2019: record stocks, lower rates, so-so IPOs
by: ALEX VEIGA, Associated Press
FILE – In this Nov. 14, 2019, file photo a pair of specialists work on the floor of the New York Stock Exchange. Investments around the world were all winners in 2019 as central banks unleashed more stimulus to bolster the global economy against the damage created by President Donald Trump’s trade war. (AP Photo/Richard Drew, File)
NEW YORK (AP) — On January 3, the S&P 500 sank 2.5% when Apple warned of sagging demand for the iPhone, an inauspicious start to 2019 following a 14% drubbing in last year’s fourth quarter.
On January 4, Federal Reserve Chairman Jay Powell said the central bank would be “patient” with its interest rate policy following four increases in 2018. The S&P 500 soared 3.4% and by the end of the month was up nearly 8%.
January’s swing helped set the tone for a year in which the market responded to every downturn with a more sustained upswing. Along the way, stocks kept setting records — 32 of them for the S&P 500 by Dec. 20, and 19 for the Dow Jones Industrial Average.
By its final policy meeting in December, the Fed had completely reversed course and cut rates three times in what Powell called a pre-emptive move against any impact a sluggish global economy and the U.S.-China trade war might have on U.S. economic growth. The stock market, and most Fed observers not named Trump, approved of the Fed’s actions.
Investors’ uncertainty over trade policy eased by December as Washington and Beijing reached a modest, interim agreement that averted a new round of tariffs on $160 billion worth of Chinese imports and reduced existing import taxes on about $112 billion in other Chinese goods.
While the pact left unresolved some of the thorniest issues between the two countries, investors appeared happy to have a de-escalation in trade tensions now and push off lingering concerns until 2020.
Through it all, the U.S. economy and consumers’ appetite for spending remained resilient, supporting the market’s record-shattering, year-end rally.
ALMOST EVERYTHING’S A WINNER
Investments around the world were winners in 2019 as central banks unleashed more stimulus to bolster the global economy against the damage created by President Donald Trump’s trade war. Not only did U.S. stocks rise, so did high-quality bonds, low-quality bonds and foreign stocks. Among the few losers: junk bonds with the very lowest credit ratings, but a better performance from bonds with bad but not the worst ratings meant high-yield indexes still generally made gains.
KEEPS ON TICKING
The U.S. economy withstood a number of challenges in 2019. President Trump’s trade war with China intensified as both sides increased tariffs. Fears of recession spiked in late summer and fall as exports fell and businesses, facing higher costs on imported goods, cut back spending on new machinery and equipment. Overseas economies also stumbled, with Germany nearly falling into recession and growth in the U.K. slowing amid Brexit uncertainty. Still, the U.S. consumer kept spending as the unemployment rate hit a 50-year low and wage growth picked up for workers outside managerial ranks. Most economists expect modest growth in 2020.
For initial public offerings, 2019 was like a year in Hollywood: There were some phenomenal successes and some notable flops. Ride-hailing giant Uber and rival Lyft were huge disappointments. Video-conference company Zoom and workplace messaging company Slack each soared on their first day of trading, but while Zoom kept zooming Slack, well, slacked off after that. For non-tech companies, Beyond Meat and its plant-based burgers hit the spot while SmileDirectClub produced mostly frowns. WeWork’s botched IPO signaled a change in IPO investors’ mindset.
TECH IS CHIPPER
Technology stocks soared in 2019 and far outpaced every other sector in the S&P 500. Chipmakers, including Advanced Micro Devices and Lam Research, made some of the biggest gains, despite a trade war that threatened business in China. Apple and Microsoft had their biggest share gains in a decade and each topped $1 trillion in market value. Energy stocks gained the least amid concerns that oil supply is outpacing demand.
EARNINGS EASE UP
Corporate profits hit the brakes in 2019, a year after a big tax cut helped juice results. On top of no longer getting the benefit of the first year of lower tax rates, a slowing global economy weighed on company revenues. If S&P 500 companies end up reporting four straight quarters of declines for 2019, as analysts expect, it would be the first time that’s happened since 2015-16. Still, analysts tend to set low expectations that most companies are able to beat, so investors aren’t panicked by the slower profit growth.
CAN NEGATIVE BE A POSITIVE?
Would you pay someone to lend money to them? The practice has become more common around the world — $13 trillion in bonds globally had negative yields as of November, according to Deutsche Bank. Much of that total is from Japan, France and Germany, countries that account for nearly a quarter of all the world’s bonds. It’s the result of shock-therapy by the European Central Bank and others to try to jolt their economies and inflation higher.
THE FED’S U-TURN
The Federal Reserve changed course on interest rate policy this year, cutting its benchmark rate three times after more than two years of increases. Chairman Jerome Powell portrayed those cuts as “insurance” against a slowdown resulting from weak global growth. Prior to late 2015, the Fed had been keeping rates at a record low near zero to stimulate the economy. In December, the Fed said it was prepared to keep rates low at least through next year.
A strong labor market and a steady decline in mortgage rates stoked demand among would-be homeowners this year, driving U.S. home sales higher. A persistently limited supply of previously occupied homes for sale at a time when millennials are increasingly seeking to become homeowners also helped to stoke demand, even though affordability remained a challenge in many markets. The housing trends favored U.S. homebuilders, whose shares surged well above the broader market.
CLICKS AGAIN OUTSHINE BRICKS
Retailers had a mixed year as they continued beefing up their online sales strategies amid declining foot traffic. Department stores, and Macy’s in particular, fell sharply. Specialty retailers did much better, with electronics retailer Best Buy, car dealership chain CarMax and home improvement retailers Home Depot and Lowe’s among those making sharp gains. As the year wound down, retailers were hoping that low unemployment, higher wages and the record-setting stock market would translate into a robust holiday shopping season.
PROTEIN PUSH
Plant-based meat has gone mainstream. Beyond Meat, which makes burgers and sausages from pea protein, had one of the most successful IPOs of the year. Burger King’s soy-based Impossible Whopper was a big hit. Tyson Foods, Nestle and Kellogg all introduced plant-based meats. Health and animal welfare concerns are driving the trend. U.S. plant-based meat sales jumped 10% this year, to nearly $1 billion; traditional meat sales rose 2% to $95 billion in that same time, Nielsen says.
Stan Choe, Seth Sutel, Paul Harloff, Damian Troise, Dee-Ann Durbin, Chris Rugaber and graphics artist Joseph Paschke contributed to this report.
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Recent FCC Orders Create Opportunities and Challenges for Counties
By Zach George Aug. 19, 2019
Tags: Telecommunications & Technology
In order to filter by the "in queue" property, you need to add the Entityqueue: Queue relationship.
FCC approved a proposed order creating the Rural Digital Opportunity Fund (RDOF), which would provide $20.4 billion over 10 years to help companies expand broadband in unserved remote areas FCC takes steps at improving broadband mapping accuracy by proposing the Digital Opportunity Data Collection (DODC), a new process for collecting broadband data to better pinpoint where broadband service is lacking FCC adopts a controversial order, which subjects cable-related, in-kind contributions to the statutory five percent franchise fee cap, jeopardizing county finances
On August 1, the Federal Communications Commission (FCC) adopted several orders that will have a significant impact on counties across the country. The approved provisions included proposals aimed at developing high-speed broadband services in rural areas and improving broadband mapping accuracy – two major county priorities. Conversely, the Commission also approved an order that classifies cable-related, in-kind contributions as a “franchise fee,” subsequently jeopardizing local finances dedicated for services such as public, educational or government (PEG) channels. Below is an overview of the commission’s actions.
Rural Digital Opportunity Fund
The FCC approved a Notice of Proposed Rulemaking for the Rural Digital Opportunity Fund (RDOF), which would provide $20.4 billion over 10 years to help companies expand broadband in unserved remote areas. RDOF will assign funding in two phases: Phase I will target areas with no broadband service and Phase II will target areas that are partially served. The program will leverage repurposed revenue from the Connect America Fund, which is set to expire in 2021. The comment period for this provision will begin 30 days after the date of publication in the Federal Register.
Digital Opportunity Data Collection
Recognizing the inaccuracies of the FCC’s broadband coverage maps, the FCC took steps to improve the Form 477 process by proposing the Digital Opportunity Data Collection (DODC), a new process for collecting broadband data to better pinpoint where broadband service is lacking. The proposal would continue to rely on provider-supplied data, but it opens the door for crowdsourcing data collection – a method supported by counties.
According to the FCC, the proposed order includes three significant changes to the process:
Collects geospatial broadband coverage maps from broadband Internet service providers. This geospatial data will facilitate development of granular, high-quality fixed broadband deployment maps, which should improve the FCC’s ability to target support for broadband expansion through the agency’s Universal Service Fund programs.
Adopts a process to collect public input on the accuracy of service providers’ broadband maps, facilitated by a crowd-sourcing portal that will gather input from consumers as well as from state, local and tribal governments.
Makes targeted changes to the existing Form 477 data collection to reduce reporting burdens for all filers and incorporate new technologies.
Stakeholders will be allowed to provide comments to the FCC regarding the proposed rulemaking 30 days after the notice is published in the Federal Register.
To address the FCC’s broadband data disparities, NACo partnered with the Local Initiatives Support Corporation (LISC), the Rural Community Assistance Partnership (RCAP), the National Association of Development Organizations (NADO) and Farm Credit, to develop “TestIT” – a mobile app designed to crowdsource connectivity data in areas with little or no connectivity. Through TestIT, users can report their broadband speeds from anywhere with the push of a button. The data collected through this app will help identify areas where broadband service is overstated and underfunded by comparing the data to the FCC’s National Broadband Map. To learn how to download the app, click here.
Third Report and Order
Lastly, on a 3-2 vote, the FCC adopted a Third Report and Order, which subjects cable-related, in-kind contributions to the statutory five percent franchise fee cap established under the Communications Act. Local franchising authorities often require cable providers to offer in-kind contributions, such as public, educational or government (PEG) channels, as a condition to a franchise agreement. These in-kind contributions, including PEG channels, provide significant public benefits to communities, such as transparency and accountability through access to local and regional government meetings; educational programming including for-credit courses; coverage of local events; local election coverage; candidate forums; and public safety programming. The order, which was strongly opposed by county governments, could contribute to a reduction of 30 to 40 percent in franchise fees resulting in a significant drop in resources for PEG channels.
The new rule is slated to go into effect 30 days after being published in the federal register, but it is expected to be challenged in federal court.
NACo will continue to work with the FCC and other broadband stakeholders to ensure key county priorities are reflected throughout the rulemaking process.
About Zach George (Full Bio)
Legislative Assistant
Zach George joined NACo in March 2016 and serves as a Legislative Assistant. He is responsible for writing and editing blog articles, conducting legislative research and providing legislative support for Environment, Energy and Land Use; Transportation; Telecommunications and Technology; and the Gulf Coast Counties and Parishes Coalition.
More from Zach George
U.S. House to vote on comprehensive package to address PFAS
House passes Digital Coast Act; bill now heads to the Senate
zgeorge@naco.org
Shared costs make broadband happen
Hackers see counties as targets
Counties losing millennials, new business due to lack of internet
2020 NACo Policy Priorities
NACo Analysis on FY2020 Spending Deal
2019 Summer Advocacy Toolkit
'Fiberhoods' are helping San Juan County, Wash. residents defray the costs of broadband expansion on the islands that make up their county.
Human error remains the weak point in cybersecurity defense, several It professionals said during NACo’s Virtual Cyber Security Symposium.
Chris Ritzo of Measurement Labs gives RAC Summit attendees an inside look at the TestIT app. Photo by Charlie Ban
Lack of reliable internet access is stifling opportunity in rural counties.
NACo works to preserve local decision making, protect counties from unfunded mandates and preemption and strengthen the federal-state-local partnership.
Nearly three months after the start of fiscal year (FY) 2020, congressional leaders were able to reach an agreement on a two-part spending deal that will fund the federal government through September 30, 2020. President Trump signed the two packages (H.R. 1865; H.R.
The August recess in the federal legislative calendar provides a unique opportunity for county leaders to communicate with members of Congress, demonstrate the impact of your efforts in your communities and advocate for the federal programs that help to strengthen local programs and initiatives.
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Home Economy Moroccan Retirement Pension Will Be Given at End of Month, Instead of...
Moroccan Retirement Pension Will Be Given at End of Month, Instead of Beginning: CIMR
Rabat - The Moroccan Inter-Professional Pension Fund (CIMR) announced on October 3 that its beneficiaries will receive retirement pensions on the last working day of each month, instead of the beginning of the following month.
Rabat – The Moroccan Inter-Professional Pension Fund (CIMR) announced on October 3 that its beneficiaries will receive retirement pensions on the last working day of each month, instead of the beginning of the following month.
The initiative is part of CIMR’s strategy to improve the quality of services offered to its beneficiaries, said the fund in a communiqué.
Founded in 1949, CIMR is a retirement company whose mission is “to promote a sustainable, balanced and supportive pension scheme guaranteeing beneficiaries a fair pension in the framework of effective management.”
The CIMR is managed by a Board of Directors elected by the General Assembly of the members.
In 2016, the CIMR had 6,276 member companies, 615,934 active contributors and beneficiaries and 164,435 beneficiaries.
The total amount of technical products of the CIMR amounted to MAD 7.719 million and the total of the pensions provided was MAD 3.780 million.
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CIMR Retirement Plan Open to Architects, Veterinarians, Self-Employed Workers
9,125 Moroccan Teachers and Professors Retired in October: Ministry of Education
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Baylor is new No. 1 in men's AP poll
🏀 South Carolina, Baylor tops in women's Power 10
Zach Pekale | NCAA.com | October 27, 2019
College football rankings: LSU passes Alabama for top spot in latest AP poll
Relive some of the best college football moments of week 9
On Saturday, LSU became the first team in the AP Poll era to win three top-10 matchups through its first eight games. Now, the Tigers are the third team in 2019 to grace the pinnacle of the AP Top 25.
Alabama seemed to have found a home as the top-ranked team in the AP Poll, holding onto the No. 1 spot for four consecutive weeks before being dethroned by the Tigers on Sunday. LSU, fresh off a 23-20 win over then-No. 9 Auburn, flipped spots with the Crimson Tide. In most weeks, Ohio State’s 38-7 rout of Wisconsin would be enough for the Buckeyes to move up. However, the Tigers' latest marquee victory coupled with Alabama's dominant performance neutralized the No. 3 Buckeyes. Clemson remained at No. 4 after a 59-7 win over Boston College.
RANKINGS: All Top 25 polls
Statements were made in Week 9 and three Top 10 teams fell, meaning there was an abundance of movement in the latest poll.
1 LSU (17) 8-0 1476 2
2 Alabama (21) 8-0 1474 1
3 Ohio State (17) 8-0 1468 3
4 Clemson (7) 8-0 1406 4
5 Penn State 8-0 1302 6
6 Florida 7-1 1226 7
7 Oregon 7-1 1108 11
8 Georgia 6-1 1093 10
9 Utah 7-1 1032 12
10 Oklahoma 7-1 1017 5
11 Auburn 6-2 910 9
12 Baylor 7-0 882 14
13 Minnesota 8-0 778 17
14 Michigan 6-2 744 19
15 SMU 8-0 666 16
16 Notre Dame 5-2 563 8
17 Cincinnati 6-1 524 18
18 Wisconsin 6-2 513 13
19 Iowa 6-2 456 20
20 Appalachian State 7-0 393 21
21 Boise State 6-1 280 22
22 Kansas State 5-2 218 NR
23 Wake Forest 6-1 200 25
24 Memphis 7-1 188 NR
25 San Diego State 7-1 50 NR
Others receiving votes: Texas 49, Navy 43, UCF 33, Washington 19, Texas A&M 14, USC 11, Louisiana Tech 6, Indiana 4, Pittsburgh 1, Oklahoma State 1, Iowa State 1
LATEST COLLEGE FOOTBALL NEWS
CFP: LSU beats Clemson for national title | Every bowl result | Shop LSU champ gear
HISTORY: National champs | Winningest teams | Coaches with most titles
MORE: How accurate are Lee Corso's picks? | 13 of the most successful walk-ons
RANKINGS: AP Top 25 Poll | USA Today Coaches | CFP top 25| Every poll, explained
Michigan and Oregon each made noteworthy forward progress this week. The Wolverines had the largest movement of any previously ranked team, surging five spots to No. 14 after a 31-point win over Notre Dame. The Ducks improved four spots to No. 7, a season-high, after a last-second field goal pushed them past Washington State.
Among the remaining undefeated teams, Southern Methodist, Minnesota, Baylor and Appalachian State all maintained perfect records and were rewarded with some significant movement in this week’s poll.
For a third straight week, Appalachian State broke the Sun Belt record for the conference’s highest-ranking ever. The Mountaineers moved up one spot to No. 20.
Baylor jumped two spots to No. 12. This is pretty significant considering the Bears, currently 8-0, finished 1-11 two seasons ago.
The last time Minnesota started 8-0 was 1941, a year the program finished as national champion. The Golden Gophers are up to No. 13, tied with Oregon for the second-largest jump this week.
SMU also remains unbeaten, earning its highest AP ranking in 34 years. The Mustangs are No. 15.
UNDEFEATED TRACKER: Nine unbeaten teams remain
Three teams entered the Top 25 this week: Memphis, San Diego State and Kansas State.
Kansas State potentially had the biggest win of Week 9, a home upset of then-No. 5 Oklahoma. The Wildcats built a 25-point lead and hung on 48-41 to shock the Sooners. Following the win, Kansas State goes from not receiving votes last week to No. 22. Memphis and San Diego State narrowly avoided defeat against Tulsa and UNLV, respectively. With a combined record of 14-2, the Tigers and Aztecs join the rankings at Nos. 24 and 25.
SOONERS STUNNED: Kansas State thwarts fourth-quarter comeback, upsets No. 5 Oklahoma 48-41
Dropping back
Seven teams in the Top 25 lost this week, three coming against ranked opponents. The most notable result was Oklahoma’s loss to Kansas State. The Sooners nearly erased a 25-point deficit, coming up just short as they slide from No. 5 to No. 10. Notre Dame dipped eight spots to No. 16 after a road loss to Michigan. Wisconsin, ranked in the Top 10 two weeks ago, is now at No. 18 after struggling against Ohio State in a second straight defeat.
Three teams — Texas (15), Iowa State (23) and Arizona State (24) — dropped out.
Outside of Baylor, ranked teams in the Big 12 had a weekend they’d presumably like to forget. Conference heavyweight Oklahoma was dealt its first loss of the year while Texas and Iowa State fell out of the rankings after losses to TCU and Oklahoma State.
For reference, this is the third straight year Oklahoma has lost in the regular season. In both of the previous occasions, the Sooners won out to reach the College Football Playoff.
No. 1 votes
Once again, first-place votes were shared among four teams. However, the number each received varies from the previous week.
Alabama drops from 24 to 21 No. 1 votes.
LSU improved from 16 to 17 No. 1 votes.
Ohio State increased from 13 to 17 No. 1 votes.
Clemson drops from nine to seven No. 1 votes.
The margins between No. 1 and No. 3 are minimal. LSU is a mere two points in front of Alabama and just six clear of Ohio State. A Week 11 matchup between LSU and Alabama may offer some clarity down the road.
Looking ahead to Week 10
Only two games feature a pair of Top 25 teams in Week 10, but both are big-ticket items. Top 10 programs Georgia and Florida go head-to-head on a neutral field while SMU and Memphis battle it out for control of the American Athletic Conference. Additionally, two of the nine remaining undefeated teams will look to steer clear of any trickery on Halloween night.
No. 6 Florida vs. No. 8 Georgia | 3:30 p.m. Saturday | CBS
No. 15 SMU vs No. 24 Memphis | 7:30 p.m. Saturday| ABC
No. 12 Baylor vs. West Virginia | 8 p.m. Thursday | ESPN
No. 20 Appalachian State vs. Georgia Southern | 8 p.m. Thursday | ESPNU
Zach Pekale is an alumnus of Arizona State University with a degree in sports journalism. He has worked for Arizona PBS, Arizona Sports 98.7 FM and the Cape Cod Baseball League. His writing has also appeared on FOX Sports, Bleacher Report and at the Associated Press. Follow him on Twitter @ZachPekale.
The views on this page do not necessarily reflect the views of the NCAA or its member institutions.
Auburn's undefeated season comes to an end and other takeaways from a wild Wednesday
Five ranked men's basketball teams lost on Tuesday night. Here are the biggest takeaways from the night.
Here are the college football programs with the most College Football Playoff wins and appearances since the format started in 2014.
Here are the college football coaches with the most national championships.
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Clin Microbiol Infect. 2012 Jun;18(6):E158-63. doi: 10.1111/j.1469-0691.2012.03841.x. Epub 2012 Apr 17.
Nepalese origin of cholera epidemic in Haiti.
Frerichs RR1, Keim PS, Barrais R, Piarroux R.
Department of Epidemiology, UCLA School of Public Health, Los Angeles, CA, USA.
Cholera appeared in Haiti in October 2010 for the first time in recorded history. The causative agent was quickly identified by the Haitian National Public Health Laboratory and the United States Centers for Disease Control and Prevention as Vibrio cholerae serogroup O1, serotype Ogawa, biotype El Tor. Since then, >500 000 government-acknowledged cholera cases and >7000 deaths have occurred, the largest cholera epidemic in the world, with the real death toll probably much higher. Questions of origin have been widely debated with some attributing the onset of the epidemic to climatic factors and others to human transmission. None of the evidence on origin supports climatic factors. Instead, recent epidemiological and molecular-genetic evidence point to the United Nations peacekeeping troops from Nepal as the source of cholera to Haiti, following their troop rotation in early October 2010. Such findings have important policy implications for shaping future international relief efforts.
© 2012 The Authors. Clinical Microbiology and Infection © 2012 European Society of Clinical Microbiology and Infectious Diseases.
Cholera/epidemiology*
Cholera/mortality
Epidemics*
Haiti/epidemiology
Vibrio cholerae O1/classification*
Vibrio cholerae O1/isolation & purification*
Cholera - Genetic Alliance
Cholera - MedlinePlus Health Information
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News»Press Releases»NCDOT Closing Lane for Repairs on U.S. 421 Bridge near Clinton
NCDOT Closing Lane for Repairs on U.S. 421 Bridge near Clinton
RALEIGH -The North Carolina Department of Transportation will close one of two southbound lanes on U.S. 421 south of Clinton for three days next week, weather permitting.
The two-mile lane closure will allow routine repairs and maintenance to be carried out on a bridge that crosses Indian Town Road in Sampson County.
The lane on U.S. 421 will close starting at 8 a.m. and ending at 4:30 p.m. on Tuesday, Sept. 18, Wednesday, Sept. 19, and Thursday, Sept. 20.
Traffic traveling south from Clinton will be directed into one lane across the bridge. Two lanes will remain open for northbound traffic.
Motorists are urged to use caution and drive slowly in the work area.
For real-time travel information any time, call 511, visit www.ncdot.gov/travel or follow NCDOT on Twitter at https://twitter.com/ncdot_triad. Another option is NCDOT Mobile, a smartphone-friendly version of the NCDOT website. To access it, type "m.ncdot.gov" into your browser and bookmark it for future reference.
###NCDOT###
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The Nonconformist’s Memorial
Susan Howe
buying options reviews
Howe has continued to produce work of meditative urgency unmatched in recent American poetry.
—Geoffrey O’Brien, Voice Literary Supplement
Poetry by Susan Howe
The Nonconformist’s Memorial is a gathering of four long sequences that underscores Susan Howe’s reputation as one of the leading experimentalists writing today. Howe is a poet of language in history whose work resonates back through Melville, Dickinson, and Shelley to the seventeenth-century Metaphysicals and Puritans (the nonconformism of the title), and forward again to T.S. Eliot and the abstract expressionists. The sequences fall into two sections, “Turning” and “Conversion,” in half-ironic nonconforming counterpoint to Eliot’s Four Quartets. Her collaging and mirror-imaging of words are concretions of verbal static, visual meditations on what can and cannot be said. For Howe, “Melville’s Marginalia” is the essential poem in the collection, an approach to an elusive and allusive mind through Melville’s own reading and the notations in his library books. This, says Howe, is “Language a wood for thought.”
Editions: Paperback
Your Independent Bookstore Barnes & Noble Amazon
Edition Data
Paperback (published June 1, 1993)
Price US
American poet and essayist
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A closer look at nanomedicine
(Nanowerk Spotlight) In our May 7 spotlight "The potential and the pitfalls of nanomedicine" we took a general look at the potential implications of nanomedicine and addressed some ethical issues that arise as the technology develops. In part two of this article we now take a closer look at emerging nanomedical techniques such as nanosurgery, tissue engineering, nanoparticle-enabled diagnostics, and targeted drug delivery. Again, the ethical issues inherent in these emerging medical technologies need to be considered. There are established principals for ethical assessment of existing, conventional, medical technologies and a new research article examines if and how these principals can be extended to nanomedicine.
"We show that even though ethical problems in nanomedicine may be more complex than ethical problems in medicine and biotechnology in general, for example the toxicity of nanoparticles resulting from their nanoscale size, fundamentally the same general ethical principles are at stake, such as respect for autonomy, beneficence, nonmaleficence, and justice" Mette Ebbesen and Dr. Thomas G. Jensen explain in their recent article "Nanomedicine: Techniques, Potentials, and Ethical Implications".
"These ethical principles have been used for ethical assessment in biomedicine for years, and they form part of several different ethical theories, including the bioethical theory of Beauchamp and Childress ("Principles of Biomedical Ethics"). This means that even though nanomedicine raises concrete ethical issues that are more complex than those raised by existing technology, a reasonably sound knowledge base has already been acquired in the field of bioethics that can be extended to nanomedicine."
Ebbesen is a researcher at the Department of Systematic Theology and Jensen is a professor at the Institut for Human Genetik, both at Aarhus University in Denmark.
Nanotechnology promises us a radically different medicine than the cut, poke and carpet bomb (think chemotherapy) medicine of today. The two major differences of nanomedicine will be a) the tools it uses – the main workhorse will be multifunctional nanoparticles (see Nanowerk Spotlight: "Creating the nanotechnology wunderkind in pharmaceutics: multifunctional nanocarriers") – and b) it will enable a perfectly targeted and individual treatment: organs and bones, really any body tissue, can be diagnosed and treated on a cell by cell basis with precise dosing and monitoring through the use of biomolecular sensors. In their paper, the authors focus on three particular areas where nanotechnology will revolutionize medicine:
Nanosurgery
Robert A. Freitas Jr. describes the early forms of cellular nanosurgery that are being explored today using pipettes, atomic force microscopes (AFM) and femtolasers: "For example, a rapidly vibrating (100 Hz) micropipette with a <1 micron tip diameter has been used to completely cut dendrites from single neurons without damaging cell viability. Axotomy of roundworm neurons was performed by femtosecond laser surgery, after which the axons functionally regenerated.
A femtolaser acts like a pair of “nano-scissors” by vaporizing tissue locally while leaving adjacent tissue unharmed. Femtolaser surgery has performed: (1) localized nanosurgical ablation of focal adhesions adjoining live mammalian epithelial cells, (2) microtubule dissection inside yeast cells, (3) noninvasive intra tissue nanodissection of plant cell walls and selective destruction of intracellular single plastids or selected parts of them, and even (4) the nanosurgery of individual chromosomes (selectively knocking out genomic nanometer-sized regions within the nucleus of living Chinese hamster ovary cells). These procedures don’t kill the cells upon which the nanosurgery was performed.
AFM have also been used for bacterium cell wall dissection in situ in aqueous solution, with 26 nm thick twisted strands revealed inside the cell wall after mechanically peeling back large patches of the outer cell wall."
Looking into the future, Freitas envisions "biocompatible surgical nanorobots that can find and eliminate isolated cancerous cells, remove microvascular obstructions and recondition vascular endothelial cells, perform “noninvasive” tissue and organ transplants, conduct molecular repairs on traumatized extracellular and intracellular structures, and even exchange new whole chromosomes for old ones inside individual living human cells."
More near-term applications of AFM and femtolaser nanosurgery most likely will include cell therapy, eye surgery, and neurosurgery, tissue engineering, laser-assisted in vitro fertilization (IVF), and gene therapy.
Ebbesen and Jensen argue that there appear to be numerous advantages of nanosurgery techniques compared with existing, mostly microscale, surgical procedures. Therefore the risk-benefit ratio of nanosurgery techniques are likely to be smaller than the risk-benefit ratio of already established microsurgery techniques. However, they caution that the exact risk benefit ratios need to be based on detailed experiments.
The ethics issue becomes more complicated if nanosurgery techniques in the future are to be used for gene therapy and the enhancement of human capabilities. Germline therapy (where the genetic changes will not only affect the patient but also his/her offspring; this is in contrast to somatic cell therapy that only affects the treated patient) is not allowed in many countries; for instance, its forbidden under the EU Convention on Human Rights and Biomedicine. By potentially making this kind of therapy easier to perform, these nanosurgery procedures are likely to lead to a renewed debate. Of course this is a double-edged sword: one one hand, opponents argue that experiments with germline therapy could be seen as tantamount to a clinical experiment on unconsenting subjects, who are the affected members of future generations. On the other hand, proponents say that human rights should not be interpreted as imposing on us morally unsustainable obligations, such as the obligation to abstain from curing people.
While the medical applications of nanosurgery could be seen as just advanced techniques of restoring and maintaining human health, an entirely possible scenario could be the creation of superhuman capabilities (so-called transhumans). The issues go beyond what's already being discussed in the context of gene therapy because future surgical procedures could involve the implantation of nanoscale sensors and chips that would enhance existing human capabilities, for instance being able to see in the dark thanks to implanted ultrasound sensors.
This raises a large number of issues – already familiar from the debate on gene therapy – ranging from moral aspects (e.g., should parents be allowed to "engineer" their children?) and equality issues (e.g., who should be offered the enhancement treatments - only people who could afford them?) to global societal implications (do industrialized nations have a responsibility to make these technologies available to developing countries?).
Nanotechnology-enabled tissue engineering is receiving increasing attention. The ultimate goal of tissue engineering as a medical treatment concept is to replace or restore the anatomic structure and function of damaged, injured, or missing tissue. At the core of tissue engineering is the construction of three-dimensional scaffolds out of biomaterials to provide mechanical support and guide cell growth into new tissues or organs (see our Nanowerk Spotlight "One day doctors will grow new bones with nanotechnology"). Experimental efforts are currently underway for tissue engineering involving virtually every type of tissue and every organ of the human body.
Ebbesen and Jensen point out that ethical analysis of tissue engineering in general requires a risk analysis similar to that required in relation to nanosurgery, and informed consent should be obtained from both the cell-donor and the participant in the clinical trial. They caution that the use of embryonic stem cells for tissue engineering and therapeutic cloning raises some specific ethical issues going beyond 'simple' tissue engineering. The ongoing debate on stem cell research reflects these issues.
Nanoparticle-enabled diagnostics and drug delivery
From an ethical point of view perhaps the least contentious are of nanomedicine involves nanoparticulate diagnostic and drug delivery methods. Having said that, the potential toxicity of engineered nanoparticles is an unsolved issue and still needs to be dealt with.
There are numerous engineered constructs, assemblies, architectures and particulate systems used for diagnostics and targeted drug delivery, whose unifying feature is their nanoscale size range. These include polymeric micelles, dendrimers, polymeric and ceramic nanoparticles, protein cage architectures, viral-derived capsid nanoparticles, polyplexes, and liposomes (as an example, see our Nanowerk Spotlight "Nanocarriers could become an alternative to brain surgery").
Throughout their discussion, Ebbesen and Jensen follow the bioethical theory of Beauchamp and Childress, mentioned above, because the principles of their theory (respect for autonomy, beneficence, nonmaleficence, and justice) find support across different cultures. The authors state, however, that "even though these principles are generally acknowledged, this does not mean that there is consensus about what is good and bad. Interesting debates occur when the principles are to be interpreted and balanced in specific historical, social, economic, and political contexts."
The authors conclude: "The analysis of potential ethical problems in nanomedicine shows that even though ethical questions in nanomedicine may be more complex than ethical questions in general medicine and biotechnology, for example the toxicity of nanoparticles resulting from their nanoscale size, fundamentally the same general ethical principles, such as respect for autonomy, beneficence, nonmaleficence, and justice, are at stake."
That means that, even though nanomedicine raises ethical issues that are more complex than those raised by existing technology, a reasonably sound knowledge base has already been acquired in the field of bioethics that can be extended to nanomedicine.
Fabricating nano- to macroscale hierarchical porous structures in a 3D printer
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Hydrogel paint - hydrogel coatings off the shelf
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Moisture-powered, multifunctional flexible sensing systems
Polymer encapsulation shields perovskite nanocrystals from degradation
3D-printing customized MXene architectures
How to turn every piece of clothing into an e-textile
Jellyfish-based nanofiber/nanoparticle wound dressing
Advanced optoelectronics with graphene-based mixed-dimensional van der Waals heterostructures
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A carbon nanotube synapse with dynamic logic and learning
(Nanowerk Spotlight) The human brain is composed of neuronal networks connected by about 1 quadrillion (1015) synapses. As inconceivably large as this number sounds, researchers are nevertheless laying the foundations for what is called neuromorphic engineering – a new interdisciplinary discipline that includes nanotechnologies and whose goal is to design artificial neural systems with physical architectures similar to biological nervous systems (read more: "Nanotechnology's road to artificial brains").
Carbon nanotubes, like the nervous cells of our brain, are excellent electrical signal conductors and can form intimate mechanical contacts with cellular membranes, thereby establishing a functional link to neuronal structures. There is a growing body of research on using nanomaterials in neural engineering (see our Nanowerk Spotlight: "Nanotechnology to repair the brain").
Carbon nanotube (CNT) synapse circuits are a first step in this direction (read more: "Researchers create functioning synapse using carbon nanotubes"). In new work, researchers at the University of California, Los Angeles, led by Prof. Yong Chen at the California NanoSystems Institute, have developed a CNT synapse with the elementary dynamic logic, learning, and memory functions of a biological synapse.
Reporting their work in a recent issue of Advanced Materials ("A Carbon Nanotube Synapse with Dynamic Logic and Learning"), the team demonstrates a CNT synapse that is operated based on the dynamic interactions between CNTs and hydrogen ions in an electrochemical cell integrated in the CNT synapse.
The structure of a carbon nanotube synapse. a) A schematic diagram showing the transistor-like structure of a CNT synapse with an electrochemical cell containing hydrogen ions in a polymer electrolyte integrated in its gate. The inset is an AFM image of a random CNT network. The average density of the single-wall CNTs is ∼8/µm2 , and the average density of the CNT bundles is ∼2/µm2 . (Reprinted with permission from Wiley-VCH Verlag)
The researchers point out that this CNT synapse consumes extremely low energy (∼7.5 pJ/spike), and the energy consumption could be significantly reduced further by scaling down the device.
These CNT synapses could be integrated in a large-scale circuit to emulate the massively parallel signal processing and learning functions of a biological neural network for speech recognition, pattern recognition, statistic inference, and other intelligent behaviors.
To fabricate the CNT synapse with a transistor-like structure, the team first coated a randomly aligned network of single-walled carbon nanotubes onto the surface of a silicon dioxide layer on a silicon chip. A 8µm by 30µm strip cut from this network was coated it with a 10nm titanium and 50nm gold layer to form the source and drain electrodes. A 90nm thick layer of polyether compound (PEG) was spin-coated and cross-linked on the top of the CNT network using electron-beam (e-beam) lithography, and a 15nm thick titanium layer and an 85nm thick aluminum layer were deposited onto the top of the PEG layer as a gate electrode. The final step was integrating an electrochemical cell in the transistor gate by sandwiching the hydrogen-doped PEG electrolyte between the CNT channel and the Ti/Al gate electrode.
The researchers tested their CNT synapse under conditions similar to a biological synapse in a customized electronic circuit. Long-term synaptic plasticity has been realized as the underlying mechanism for learning and memory in the brain. The long-term plasticity behavior of the CNT synapse was demonstrated by modifying the synaptic strength with pre- and post-synaptic spikes.
The team also notes that the synaptic strength in a CNT synapse can be continuously and reversibly modified to desired analog values by applying a series of pre- and post-synaptic spikes with different amplitudes.
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Prep cross country 2016: Lely wins Class 2A-12 meet
The Lely girls squeezed by LaBelle by just one point behind Rosie Poling's first place and Ryenn Hart's second place finish to earn the district title. Poling, who also won the district title last season, finished in 20:09.
Prep cross country 2016: Lely wins Class 2A-12 meet The Lely girls squeezed by LaBelle by just one point behind Rosie Poling's first place and Ryenn Hart's second place finish to earn the district title. Poling, who also won the district title last season, finished in 20:09. Check out this story on naplesnews.com: http://nplsne.ws/2eBPwm0
Kelli Krebs, kelli.krebs@naplesnews.com Published 5:33 p.m. ET Oct. 21, 2016
Lely's Josh Wagner reaches for the finishline during Friday morning's District 2A-12 meet at Lely High School.(Photo: Kelli Krebs / Naples Daily News)Buy Photo
The Lely High School cross country teams won the Class 2A-District 12 championship behind two individual first-place finishes Friday morning.
The Lely girls squeezed by LaBelle by just one point behind Rosie Poling's win and Ryenn Hart's second-place finish to earn the district title, despite having two of its top runners out with injuries.
"I'm very excited about what's happening and what we did, but now we've got to race for regionals," Lely coach Mark McGarity said. "To do this today was a great team effort by both teams -- it was a little stressful. We were concerned about some stuff -- but they pulled it through. Now we're going to see what they can do in another week."
Lely's Rosie Poling races during Friday morning's District 2A-12 meet at Lely High School. (Photo: Kelli Krebs / Naples Daily News)
Poling, who also won the district title last season, finished in 20:09.29, more than 20 seconds ahead of second place. Poling, a senior who's been racing with the Trojans for four years, said she tried to soak up as much of her final run on her home course as possible.
"It just means a lot," Poling said. "Just running the course today I was thinking about 'This is the last time running through the woods and around the school.' So it was an emotional race, but I tend to run better on emotions."
NAPLES DAILY NEWS
Prep cross country 2016: Naples High School claims CCAC title
For the boys, senior Josh Wagner added another title to his first-year resume as a cross country runner. Wagner, who finished the redesigned Palmetto Ridge course in record time at the Collier County Athletic Conference championship last week, pulled in front of LaBelle's Yoan Prado on the last straight-away for a 16:30.66 finish.
"I just unloaded the tank," Wagner said. "I had a lot of fun running against Yoan, I'm excited to run with him at states. He's a good runner and we push each other. I thought everyone else out here ran great."
Prep cross country 2016: Lely wins district 2A-12 championship
Lely's Josh Wagner reaches for the finishline during Friday morning's District 2A-12 meet at Lely High School. Kelli Krebs / Naples Daily News
Lely's Rosie Poling races during Friday morning's District 2A-12 meet at Lely High School. Kelli Krebs / Naples Daily News
Local runners compete for regional spots during Friday morning's District 2A-12 meet at Lely High School. Kelli Krebs / Naples Daily News
Lely's Josh Wagner makes the turn during Friday morning's District 2A-12 meet at Lely High School. Kelli Krebs / Naples Daily News
Rosie Poling races toward the finish line during Friday morning's District 2A-12 meet at Lely High School. Kelli Krebs / Naples Daily News
Poling and Wagner, along with 11 other Lely runners from the boys and girls teams, qualified individually for next week's regional meet in Lakeland with top-15 finishes. Lely's boys team finished with a little more cushion with 39 points, while Immokalee finished second with 64 points. LaBelle and Immokalee also qualified both teams while Dunbar qualified its boys team and Bishop Verot qualified its girls team.
"When your team's there it makes it 100 times better," Poling said. "I'm really, really excited for it because it's always a great time to challenge yourselves as a group."
Class 2A-District 12 cross country meet
at Lely
Team scores
(Top 4 advance)
Lely 39, Immokalee 64, LaBelle 64, Dunbar 66, Oasis 148, Bishop Verot 161, Clewiston 161.
Individual qualifiers
(Top 15 advance)
1. Josh Wagner (L), 16:30.99; 2. Yoan Prado (LB), 16:33.11; 3. Brendon Herrera (LB), 17:11.48; 4. Cody Demalavez (L), 17:21.32; 5. Erasmo Cortez Cruz (I), 18:06.38; 6. Mackenson Yrelus (I), 18:08.21; 7. Ellerman Mateo (I), 18:08.81; 8. Ralph Claude (D), 18:13.59; 9. Michael Poling (L), 18:13.73; 10. Trevor McDaninel (D), 18:17.18; 11. Garett Southerland (L), 18:17.44; 12. Damien Simmonds (D), 18:25.74; 13. Terrell White (D), 18:26.74; 14. Jose Rodriguez Romero (L), 18:28.93; 15. Eric Martinez (L), 18:30.54.
Lely 40, LaBelle 41, Immokalee 63, Bishop Verot 122, Dunbar 134, Clewiston 137.
1. Rosie Poling (L), 20:09.29; 2. Ryenn Hart (L), 20:32.28; 3. Esmeralda Rodriguez (LB), 21:30.07; 4. Katelyn Bryant (C), 21:59.06; 5. Lexy Barraza (LB), 21:59.37; 6. Brandy Vilsaint (I), 22:30.62; 7. Alondra Reyna (LB), 22:32.21; 8. Valerie Gonzalez (I), 22:33.27; 9. Jacqueline Leon (LB), 22:33.58; 10. Ryann Leaman (L), 22:38.76; 11. Julia Canzano (BV), 22:39.32; 12. Bailey Greaves (L), 22:45.25; 13. Melissa Ruiz (I), 23:05.21; 14. Maricela Busio (I), 23:12.81; 15. Emma Fernandez (L), 23:14.60.
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New sorghum variety a sure money spinner
Friday February 14 2014
Researchers and Ministry of Agriculture officials tour Egerton University's hybrid sorghum evaluation plots at Kipsyenan in Rongai District. Scholars have now called on the government to sensitise farmers on the nutritive and economic benefits of growing sorghum. They say sorghum does well in drought-prone areas and requires less costly inputs making it fit the description of the most effective 'hunger-destroyer’. PHOTO/FILE.
At the same time, Dr Cheruiyot said an engineer from the Agricultural Engineering Department at Njoro Campus was developing a sorghum thrasher to help farmers reap maximum profits from their crops.
By FRANCIS MUREITHI
Researchers at Egerton University are working on an ambitious project to enhance sorghum production.
The project comes at a time when more than 1.7 million Kenyans are facing starvation due to poor rains and dwindling harvests of traditional staples such as maize and beans due to erratic weather conditions.
Sorghum, cassava and millet are some of the crops classified as ‘orphaned’ and which have been neglected by farmers due to lack of certified seeds.
The crops have remained unattractive to most farmers yet they have high nutritional value and could be the answer to malnutrition in arid areas.
The researchers say the new varieties will be drought resistant and high-yielding, making them ideal for arid and semi-arid areas.
Most farmers planting sorghum use previous harvests as seeds, resulting in poor yields.
“Our project is aimed at identifying sorghum varieties that could be put to industrial use and developing hybrid seeds that farmers could grow to improve their incomes and livelihoods,” says the lead researcher, Dr Erick Cheruiyot.
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Speaking to the Seeds of Gold, Dr Cheruiyot said the project, which was started in July 2011, also aims at promoting the post-harvest handling of sorghum and processing besides linking farmers to sustainable markets.
“Sorghum farmers in Kenya will only enhance their production if they are sure that there is a ready market for their products,” says Dr Cheruiyot, who is a specialist in crop physiology and a senior lecturer in the Department of Crops, Horticulture and Soils.
The team has identified high-yielding varieties to boost production.
“Some of the varieties that are undergoing tests could yield six tonnes per acre and this is a big improvement from the two tonnes by the variety the farmers are using,” said Dr Cheruiyot. The researchers are collaborating with the International Crops Research Institute for the Semi–Arid Tropics, an agricultural research organisation from India.
Egerton University Deputy Vice Chancellor for Research and Extension, Prof Gowland Mwangi, says the identification of the varieties was a big breakthrough in the fight against hunger in the country.
He says the university had signed an agreement with the Ministry of Agriculture and Kenya Agricultural Research Institute to carry out comprehensive research in seeds and animal husbandry.
It’s also working with the Bomet County government to rehabilitate dams and other water sources.
“Our researchers are working with the county government to ensure that the dams are well rehabilitated and hold water for a long time to help residents increase food production through irrigation,” said Prof Mwangi.
A similar project is being undertaken with the Uaso Nyiro Development Authority for 10 counties in Northern Kenya.
“Apart from helping these counties in the Northern Kenyan to manage their water resources well, the university is also helping them develop disease-tolerant crops such as cassava, millet and sorghum,” he said.
Sorghum thrasher
“This machine, once in the market, will ensure cost-effective threshing and hygienic handling of sorghum grain,” Dr Cheruiyot says.
Sorghum farmers will reap from the multi-billion beer industry if brewers adopt a new policy spelt out during the 2013/14 financial estimates that promotes its use as an ingredient in making cheaper alcoholic beverages.
The Cabinet Secretary in charge of The Treasury, Mr Henry Rotich, exempted beer made from millet and cassava from excise duty.
The researchers say the new policy will stimulate agricultural activity and provide a ready market.
This could translate into high returns for brewers.
“The huge amounts spent by the beer companies to import barley could be channelled to research to improve production,” he says.
Dr Cheruiyot a variety of sorghum that produces a lot of sugar is used in production of ethanol.
In Nyanza, cylinder maker East African Spectre will this year start using sorghum following a shortage of molasses growing sorghum owing to the shortage of molasses. Last year farmers from the region earned Sh480 million from the crop.
In Rift Valley, the acreage under sorghum increased from 9,960 to 13,677 hectares last year, while production improved from 18,740 to 146,180 bags.
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Home Car Hire Global Destinations Canada Alberta Fort McMurray Airport Syncrude FBO
Fort McMurray Airport Syncrude FBO Car Hire
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Renter may purchase Roadside Plus (RSP) from Owner for an additional fee. If Renter purchases RSP, Owner agrees, subject to the actions that invalidate Loss Damage Waiver, to contractually waive Renter’s responsibility for the cost to provide 24/7 roadside assistance (where available) which includes replacement of lost keys (including remote entry devices), flat tire service (if no inflated spare is available, the vehicle will be towed. Cost of a replacement tire is not covered by RSP), lockout service (if the keys are locked inside the vehicle), jumpstarts, and fuel delivery service for up to 3 gallons (or equivalent liters) of fuel if Vehicle is out of fuel. Roadside Plus services are only available in the United States and Canada. If Renter does not purchase RSP, or RSP is invalidated as set forth above, roadside assistance will be available, but standard charges will apply. RSP does not apply in Mexico. For roadside assistance call 1-800-268-9711.
Expand or Collapse Renter Requirements
All renters and additional drivers must be 21 or older, have a valid drivers license and a major credit card in their name. Drivers licenses are accepted from any USA state or territory, from a Canadian province or from an international country. International renters require a valid passport; the name on the passport must match the name on the drivers license. Licenses from outside the USA or Canada also may require an international drivers permit. International drivers permits are valid only if presented with the original local license. International renters require a valid passport; the name on the passport must match the name on the drivers license. Individuals with learners permits are not eligible to rent. U.S. government employees ages 18 or older will not incur a young driver surcharge when renting for authorized government travel. This is only a summary. For additional details, please reference the Drivers License Information Policy.
AGE -
The underage surcharge for drivers between the ages of 21 and 24 is $20.00 CAD per day. Renters between the ages of 21 and 24 may rent the following vehicle classes: Economy through Full Size cars, Compact and Intermediate SUVs.
NON CREDIT CARD DEPOSITS -
Debit cards are not accepted as a form of deposit or payment.
DEPOSIT AMOUNT -
A deposit including an additional $200.00 CAD more than the cost of the rental will be taken at the time of rental, and the funds will not be available for use until after the vehicle has been returned. Money orders are not acceptable methods of deposit.
Expand or Collapse Toll Pass Policy
Our TollPass Program is our electronic toll collection program which allows our renters to drive through electronic toll lanes and pay tolls electronically, without having to stop and pay cash. In addition, many toll plazas have converted to all electronic tolling and removed the option for travelers to stop and pay cash at toll plazas.
The TollPass Program is offered in different ways, depending on where you rent. Visit the websites below for more information.
• Northeast US (including regions in the Midwest):
https://www.nationalcar.com/en_US/car-rental-faqs/use-toll-lanes/northeast-us-toll-options.html
• Massachusetts:
https://www.nationalcar.com/en_US/car-rental-faqs/use-toll-lanes/massachusetts-toll-options.html
• Chicago Metropolitan Area:
https://www.nationalcar.com/en_US/car-rental-faqs/use-toll-lanes/chicago-toll-options.html
• Golden Gate Bridge and Northern California Bay Area:
https://www.nationalcar.com/en_US/car-rental-faqs/use-toll-lanes/northern-california-toll-options.html
• Southern California:
https://www.nationalcar.com/en_US/car-rental-faqs/use-toll-lanes/southern-california-toll-options.html
• CO, FL, TX, NC, GA, WA, PR, and Ontario Canada:
https://www.nationalcar.com/en_US/car-rental-faqs/use-toll-lanes/other-state-toll-options.html
• Louisville KY:
https://www.nationalcar.com/en_US/car-rental-faqs/use-toll-lanes/indiana-kentucky-toll-options.html
• Utah:
https://www.nationalcar.com/en_US/car-rental-faqs/use-toll-lanes/utah-toll-options.html
To view our entire coverage map, go to https://www.nationalcar.com/en_US/car-rental-faqs/use-toll-lanes.html and click on Coverage Map.
TollPass products not available at all locations or at locations operated by a Licensee. Please refer to your rental locations policies and/or offerings for toll products to determine availability of TollPass programs.
Expand or Collapse Winter Tires
Winter tires are offered during certain months and based on availability at the rental location. If you wish to request winter tires ahead of your vehicle reservation date, please contact the rental office directly for availability and pricing.
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The Obama Doctrine
About Victor Davis Hanson
Follow Victor Davis Hanson on Twitter
The problem with Obama’s Middle East policy is that there is no policy, and that’s why we have heard nothing consistent or comprehensive from the administration that would try to explain our glee at Mubarak and Ali leaving but outreach to the far worse Assad, the monster Ahmadinejad’s enjoying exemption from “meddling” butQaddafi’s being merely “unacceptable,” talk of going into Libya as good but no talk of Saudi Arabia going into Bahrain as good or bad, reset diplomacy as not judging other regimes but human rights declared universal, no idea whether plebiscites without constitutional guarantees will bring governments worse than the pro-American autocracies that fall, and loud declarations of Bush’s policies as bad but also reset diplomacy’s quietly embracing most of them in Afghanistan, Iraq, and the not-to-be-named war on terror.
All this is in line with simultaneously establishing withdrawal dates and surging into Afghanistan, virtually closing Guantanamo, and regretting Iraq while claiming it as a possible “greatest achievement.” All that can be said for it is that the chaos keeps our friends and enemies guessing — and that confused inaction is, I suppose, preferable to confused intervention.
What then is or was at the heart of U.S. bewilderment in the region?
Three flawed assumptions:
1) Not being George Bush meant that we should keep mum about “democracy” and “human rights” and not judge the culturally constructed practices of ‘other’ indigenous governments. We saw that rhetoric early in 2009, and it was reified by our silence over the Iranian protests six months later. Oddly, we were to assume that a right-wing Bush had been too idealistic, and that a left-wing Obama was going to return to realpolitik dressed up in multicultural platitudes of non-intervention. The result is that we have become loud multicultural neocons who sermonize but are not taken too seriously;
2) We trumpeted multilateralism in the sense that we would follow the lead of the U.N. or the EU/NATO or the Arab League, all of whom are always waiting to follow America’s lead. Apparently, the administration believed that the usual serial criticism from these international bodies meant that they don’t like U.S. leadership. In fact, they both do like us to lead and even more do like to criticize us for leading — and find absolutely no contradiction in that at all. The result is that they are all unhappy that they finally got what they have always wanted and did not want.
3) As we saw in Obama’s first interview (with al Arabiya), his Cairo speech, and commentary from his advisers, the president as Barack Hussein Obama believed that his unique racial heritage, his non-traditional name, his father’s Muslim ancestry, and his left-of-center politics were all supposed to combine to reassure our former enemies and suspicious neutrals that we were now on the right side of progressive history-making — as if a democratic, capitalist, wealthy military superpower could at last be seen as quasi-revolutionary, and therefore they should both like us and desist from inappropriate behavior. It was almost the foreign-policy equivalent of a stuffy, big-city establishment organization cynically hiring a hip community-organizing liaison to go out into the neighborhood and convince suspicious locals that it was ‘really’ on their side — and it has worked about as well as these things usually do for all parties involved.
So where do we go from here? In the next crisis, I suggest that we can always boycott the Olympics.
return-icon Return to The Corner
NRO contributor Victor Davis Hanson is the Martin and Illie Anderson Senior Fellow at the Hoover Institution and the author, most recently, of The Case for Trump. @vdhanson
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Steel Panther at The Beacham in Orlando, FL on 07-May-2015
Colleen O'Neil
Anthony "Tiny Bubz" Biuso Interview at NAMM 2015
Dan Davidson Releases Heartwarming Music Video
Country, Music Videos, US
Michael Schenker Fest "Live" Tokyo
Album Reviews, Rock, UK
Avatar drops “The Eagle Has Landed”, Hitting North America on World Tour and with BABYMETAL
Artist Feature, Rock, US
Ozzy Osbourne's No More Tours 2 UK and European Tour Leg Postponed Due To Illness
Steely Dan and Elvis Costello at Hollywood Casino Amphitheatre in St. Louis, MO on 22-July-2015
Steely Dan returns to touring, featuring impressive musicianship and fan-favorite songs in their two hour set.
Steely Dan, formed by a 43-year musical partnership between Walter Becker and Donald Fagen, returned to touring, making a stop in St. Louis at Hollywood Casino Amphitheater. Although Becker and Fagen form the core duo of the band, the 2015 touring ensemble consisted of eleven other members, all of whom are accomplished and extraordinary musicians in their own right. Each of them was featured during the band’s two hour set, giving each individual a chance in the spotlight.
Although Becker has long been revered as a consummate guitarist, the band’s second guitarist, Jon Herington, left the crowd in awe as he and Becker traded licks on a sped-up “Bodhisattva” and played the majority of solos on the other tracks.
Becker and Fagen took their own turns as the center of attention–Becker acting as the show’s emcee and playing more leads than he has in the past, while Fagen gave off a Ray Charles-type vibe, wearing sunglasses and swaying behind his keyboard. The band swept through nineteen songs, which included many former hits and fan favorites, along with a few deeper cuts and a few cover tunes.
Although they relied heavily upon older material–the band has not had a new release since 2003’s Everything Must Go–it did not diminish the subtle complexities underlying even the catchiest of their hit songs and the impeccable performance of the band, both as individuals and as an ensemble.
Steely Dan Set List:
Teenie’s Blues (Oliver Nelson cover) (band instrumental without Becker/Fagen)
Hey Nineteen
Time Out of Mind
Show Biz Kids
Godwhacker
Razor Boy (Sung by The Danettes)
Daddy Don’t Live in That New York City No More
Babylon Sisters
I Want To (Do Everything for You) (Joe Tex cover)
My Old School
Reelin’ in the Years
Kid Charlemagne
The Untouchables (Nelson Riddle cover) (band instrumental without Becker/Fagen)
Elvis Costello & The Imposters opened the show, playing an hour’s worth of crowd-pleasing material, focusing strongly on past popular hits. St. Louis has not had the privilege of an Elvis Costello tour in fifteen years, until 2015 brought him into town twice. Fans were ecstatic, many singing along to the majority of his set.
Backed by his longtime band, The Imposters, Costello and the band rocketed through a deep catalog of Costello’s solo material as well as material by his other backing band, The Attractions. The Imposters were economical, both in their musicianship and movements, but did loosen up a little during “One Bell Ringing,” giving the audience a taste of their deep talent.
Elvis Costello Set List:
I Hope You’re Happy Now (Elvis Costello & The Attractions cover)
High Fidelity (Elvis Costello & The Attractions cover)
Watching the Detectives (Elvis Costello & The Attractions cover)
Accidents Will Happen (Elvis Costello & The Attractions cover)
(I Don’t Want to Go To) Chelsea (Elvis Costello song)
Flutter & Wow
One Bell Ringing (Elvis Costello song)
Jimmie Standing in the Rain (Elvis Costello song)
Veronica (Elvis Costello song)
Everyday I Write the Book (Elvis Costello & The Attractions cover)
(The Angels Wanna Wear My) Red Shoes (Elvis Costello song)
Pump It Up (Elvis Costello song)
Alison (Elvis Costello song)
(What’s So Funny ’bout) Peace, Love and Understanding (Brinsley Schwarz cover)
Hollywood Casino Amphitheatre
Elvis Costello & The ImpostersHollywood Casino AmphitheatreMissouriSt LouisSteely Dan
P.O.D., Hoobastank, and From Ashes to New at Pop’s in Sauget, IL on 16-July-2015
Brett Ditgen of Red Line Chemistry Interview
Colleen was always the kid with the camera, taking snapshots of anything and everything she found interesting. Fast-forward to her teen years, where she spent much spare time and money on seeing as many live rock 'n roll acts as possible, both established and up-and-coming bands, and having a camera in hand. Colleen works to capture those moments that draw the viewer in and define the mood and energy of the artists and their performances.
Cross Examination, Pig Champion at Fubar in St. Louis on 24-May-2014
Concert Imagery: The Atom Age and Candy Coated Evil @ FUBAR in St Louis, MO on 3-April-2014
Drop D Dave and Colleen O'Neil
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NJArts.net (https://www.njarts.net/350-jersey-songs/suburbia-adrenaline-o-d/)
‘Suburbia,’ Adrenalin O.D.
By: JAY LUSTIG | September 1, 2015
Adrenalin O.D. (from left, Paul Richard, Jim Foster, Dave Scott and Jack Steeples) in a vintage publicity photo.
Never was a band more more perfectly named than Adrenalin O.D., a hardcore punk group that helped add a dose of humor to the genre in the mid-’80s, while keeping the songs as fast and loud and bratty as anyone else. Their hometowns were East Paterson (now Elmwood Park), Union, Madison and Clifton, and mocked suburban life, among a great many other things. Their 85-second anthem “Suburbia,” for instance, lashed out at the Livingston Mall (“Nothing to buy, too many stores”) and other easy targets.
“Suburbia” came out on Adrenalin O.D.’s 1983 EP Let’s Barbeque, and then on their debut 1984 full-length, The Wacky Hijinks of Adrenalin O.D. You can listen to it below and, since the words go by in a bit of a blur, here they are:
Houses are spread out too far
Too many trees and too many cars
Everyone works or everyone hides
Too many birds in suburban skies
Too many burnouts, too many jocks
Middle class scumbags, think they’re smart
They go to school and comb their hair
And always have the right clothes to wear
Suburbia! Suburbia!
Go hangout at the Livingston Mall
Nothing to buy, too many stores
Too many joggers on the streets
Gonna run ’em over in my beat up car
Go for a walk through the center of town
Or hop in the car and cruise around
Mow the lawn, take out the trash
Go in mom’s pocketbook and take her cash
Adrenalin O.D. broke up in 1990, but has reunited occasionally since then. They’ve got a New Jersey show coming up this Fall, performing at the Stanhope House in Stanhope on Oct. 25.
New Jersey celebrated its 350th birthday in 2014. And in the 350 Jersey Songs series, we marked the occasion by posting 350 songs — one a day, from September 2014 to September 2015 — that have something to do with the state, its musical history, or both. To see the entire list, click here.
350 Jersey Songs
350 Jersey Songs: 'White Castle Blues,' The Smithereens
An anthem to late night hamburger meals.
350 Jersey Songs: 'I Am a Patriot,' Little Steven
'Nothing But Time,' Jackson Browne
View all 350 Jersey Songs Posts →
Willie Nile, Nicole Atkins to perform at Fall Hoboken Arts and Music Festival
NJ native Bob Malone finds inspiration in New Orleans music
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Oceania Football Confederation > News > 2018 OFC Champions League > Fifi’i thrilled to be back on home soil
Fifi’i thrilled to be back on home soil
in2018 OFC Champions League
Lupe Ole Soaga midfielder Michael Fifi'i in action during the OFC Champions League Qualifier last month.
Solomon Islander Michael Fifi’i is thrilled to be back in his homeland, with his return coming courtesy of Samoan outfit Lupe Ole Soaga who will feature in Group D of the OFC Champions League this weekend.
It will be the midfielder’s first time playing on home soil since 2005, a 12 year wait that has been a long-time coming, he said.
“To me it means a lot and probably means everything in football to be coming home to play in front of my own people,” Fifi’i said.
“The OFC Champions League is giving me another opportunity to play in front of my people after 12 long years. The last time was with the U-20 national team back in 2005.
“It’s a special homecoming for me not just as a Solomon Islander, but as a footballer.”
Fifi’i and his teammates have hit the ground running with trainings at SIFF Academy and DC Park since their arrival on Tuesday.
Having come through the Qualifier, he knows that his side are very much underdogs but believes they can turn heads.
“I can’t wait to walk out onto the Lawson Tama pitch, but as a team our boys are looking forward to it.
“These boys are talented and Solomon Islands will be shocked to see the young generation of Samoans come February 25th when we play our first match,” he predicted.
Lupe Ole Soaga coach Paul Ualesi stressed that Fifi’i is an important member of the squad.
“For now Fifi’i is no longer a Solomon Islander, he is a Samoan now,” Ualesi laughed.
“Our brother Fifi’i is one of the most experienced and a really good character for the team.
“I think it is good for the boys to learn from him both on and off the pitch, and I think many locals will support our team because of Fifi’i.”
The OFC Champions League 2018 Qualifier runners-up Lupe Ole Soaga open their Group Stage campaign against 2017 semi-finalists AS Magenta at 1pm (local) at Lawson Tama Stadium.
Story by Simon Abana, Solomon Star
Lawson Tama Stadium, Lupe Ole Soaga, Michael Fifi'i, OFC Champions League, Samoa, Solomon Islands
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Dunedin’s latest ‘tour bus’ a V8-powered bike
By Margot Taylor
Andrew Sim drives his new 350 Chev-powered trike up Highcliff Rd with (from left) Rachel Horrell (19), Ava (19) and Nick and Mark Fraser yesterday. Photo: Stephen Jaquiery
A Dunedin man is set to show off the city he loves on a $130,000 five-seater trike.
The 350cu in V8 Chevrolet-powered trike will cruise along the roads of Otago Peninsula, Brighton and the inner city on a series of tours in which visitors are guaranteed to feel the wind in their hair.
Trike owner-operator Andrew Sim said there were four other five-seater trikes in New Zealand but it would be the first such vehicle to operate in Dunedin.
The vehicle is registered as a car, which means occupants do not have to wear a safety helmet. It was built by Christchurch trike maker James D.
Mr Sim said the idea for the machine came about after he finished a business degree at the University of Otago.
The venture fuses the Speight’s tour guide’s two passions - Dunedin and showing it off to tourists.
"I really enjoy taking tours and showing people what Dunedin has to offer."
While he had only had the trike for a week, it had already attracted plenty of attention when it was parked in the Octagon.
The trike was "very easy to drive" and came complete with heated bucket seats and USB ports for technology-minded passengers.
The trike would offer fun but safe tours.
"It gets to the speed limit very quickly, but it only goes the speed limit," he said, laughing.
Trike passenger Ava (19) said travelling on the vehicle was like being on a "scenic rollercoaster".
Mr Sim would offer tours doing anything "within the law" and he expected clients ranging from the young at heart to children and their parents.
Tours would begin once signwriting was completed this week, he said.
margot.taylor@odt.co.nz
flatout Fri, 24/02/2017 - 8:54am #
Nice one, I should register my bike as a car, I don't want to wear a helmet either.
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> OPSI Blog > Creating a new norm: moving innovation from the margins to the mainstream
A scan of the Israeli public sector innovation system
Audit and innovation: an uneasy relationship
Announcement: #CallforInnovations at the Edge of Government (deadline extended: 21 February 2020)
The power of connections in an innovative public sector
Innovation in education governance: Toward a Learning System in Wales
Country Studies (6)
How to innovate (51)
Innovation Declaration (9)
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Innovation Lifecycle (6)
Innovation Skills (6)
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Updates on the OPSI (34)
chea vuthna on Audit and innovation: an uneasy relationship: “Agree with you that innovation, one way can be offered by internal auditors but auditees usually try to evade the…” Jan 16, 00:14
Jamie Berryhill on Announcement: #CallforInnovations at the Edge of Government (deadline extended: 21 February 2020): “Hi Julie -- Thanks for your question. Yes, we are looking for projects and initiatives at all levels of government.” Jan 15, 15:15
Julie on Announcement: #CallforInnovations at the Edge of Government (deadline extended: 21 February 2020): “Can we apply if we're working with local governments , not central government, such as municipalities or regions?” Jan 15, 09:49
Alex Roberts on Innovation is a many-splendoured thing: “Hi Avery - thanks for the positive feedback. FYI, our updated diagram for the facets can be found at https://www.oecd-opsi.org/projects/innovation-facets/,…” Jan 13, 14:20
Avery Sen on Innovation is a many-splendoured thing: “Always love endorsements from Stephanie Wade!” Jan 6, 20:45
Creating a new norm: moving innovation from the margins to the mainstream
Written by OPSI, OPSI Staff on 24 April 2017
Event, How to innovate
This blog was authored by guest blogger, Benjamin Kumpf Policy Specialist, Innovation, United Nations Development Programme
“We are trying to prove ourselves wrong as quickly as possible, because only in that way can we make progress.” Richard Feynman, Noble Prize winning physicist, emphasized this paradigm as guiding principle for work in natural sciences. Based on what we have learned over the last three years in the Innovation Facility in the United Nations Development Programme (UNDP), we argue that such a paradigm is not only applicable to policy-making and public sector innovation – it is needed.
Moving from ‘making the data fit the theory’ to ‘adjusting the theory to the data’, or in another words, an experimental approach that does not fetishize failure, is at the heart of successful public sector innovation.
UNDP is among the growing number of international development organizations that invests in innovation. The journey started in Eastern Europe and Central Asia in 2012 and matured to a global Innovation Facility. This Facility is essentially a small startup within a large bureaucracy and as every start-up it comes with a value and growth hypothesis: by bringing in new ways of working and testing new models, better development outcomes will be achieved. That is the value hypothesis and the core of our work: focus on the change you want to achieve, not the solution.
The growth hypothesis is that testing and scaling new approaches will result in new service lines for the organization. Indeed, independent evaluations show that UNDP Country Offices that have successfully adopted innovation principles designed new services, embedded cutting-edge skills into their own teams and those of their clients, and mobilized new streams of funding for human development. UNDP remains one of the few UN agencies that supports governments in setting up Public Sector Innovation Labs to experiment with new approaches to policy-making and that advises government partners on designing Open Innovation Prize Challenges.
In addition to scanning the horizon for promising models and emerging technologies that have the potential to improve policy-making and service delivery, the Innovation Facility has a change management mandate, comparable with many Government Labs that also aim at updating the modus operandi of their respective public sector.
Making innovation the new normal requires a variety of interventions. We drive innovation through a decentralised fund with support from the Governments of Denmark and the Slovak Republic, and UNDP’s own funds. The investments in more than 130 experiments since 2014 have resulted in better development solutions and new service lines. Our report, ‘Innovation for 2030’, presents our innovations that are scaling along with the early-stage initiatives.
To drive innovation, we developed our own innovation framework and endorsed it with senior management support. We work with our Talent Management Team on providing managers with support to enable innovation. The UNDP Leadership Development Pathway entails a pillar on innovation and provided more than 500 managers in the organisation with skills in human-centred design and social innovation. We drive innovation by providing tools that help colleagues and partners in their endeavors to change business as usual. Examples include the DIY Toolkit produced by our partner Nesta, the Toolkit for Troublemakers and others. We launched Innovation Champion programmes in four regions, deliberately with distinct designs to assess their comparative advantage.
Yet, innovation remains on the margins of the organization. It is driven by the passionate, curious ones who are not satisfied with how business is done. The tools and support mechanisms developed by the Innovation Facility and its partners are helpful for those who are willing to go extra miles and work outside of the system but they will not establish a new norm.
We have realized that our innovation framework is too distant from how people in the organization operate. More needs to be done. Here are the pillars of our next experimentation phase to bring innovation to the core how ‘things are done around here’.
1. Embed in innovation in project management procedures
Public sector organizations like UNDP usually have strict rules on how business is done. This is a core strength for any organization that strives for transparency and accountability. The downsides, however, are inflexible multi-year planning instruments, risk aversion, and in some cases concepts of scale that prioritize standardization over adaptation.
Our team in the UNDP Regional Istanbul Hub led the design of tools that help colleagues deviate from the current linear implementation paradigm, offering new ways to work at any stage of a programme or project cycle, and design for adaptive scale from the get-go.
Our key assumption is that if methods that enable experimentation are part of the organization’s DNA, we will see an uptake in their use and eventually produce better programmes and projects. So we ‘hacked’ the corporate programme guidance and developed the ‘Project Hacker Kit’, working closely with four UNDP Country Offices over months.
The ‘Hacker’s Kit’ does not offer quick solutions but rather helps managers and practitioners ask tough and useful questions. Are there positive changes already happening in the system? Can we identify positive deviants? What are probable future scenarios and challenges for the system? How can we reformulate activities to a set of assumptions and hypotheses and test them? How can we design solutions with end users? Have we tested different models to make a strong business case before going into piloting? The Hacker’s Kit strives to find a balance between making systems-thinking practical and designing evidence-based experiments that inform the next steps of a programme.
We developed a physical asset, a deck that looks like a board game with question cards, to initiate more stimulating conversations. Having something to engage with has so far proven to kickstart more engaged conversation than discussions without our ‘board game’.
2. Invest in skills-building
Just like national public sector organizations, international organizations will have to transform largely with the staff they have on board. Bringing in new talent with innovation skills will not suffice. Fostering innovation skills in the public sector thus becomes a fundamental for UN agencies and UN Member States alike. But what are the most important skills to nurture? What are most cost-effective ways to ensure that a relevant number of staff members have the required skills and capabilities?
To answer the first question, we partnered with Nesta and investigated how successful innovation champions within UNDP trigger and manage change. Based on the observations of the positive outliers and ongoing work of Nesta and the OECD Observatory for Public Sector Innovation we identified four core functions:
Opportunity: How to identify new and promising ways of working?
Challenge: How to productively challenge the status quo?
Inspiration: How to inspire colleagues and management to make a shift?
Diagnosis: How to work with teams to identify the most suitable entry points for innovation?
The required skills to successfully execute these functions are data literacy, the ability to manage iterative processes and user centricity. The opportunity function means to develop the skills required to scan the horizon for promising new ways off solving problems.
How to best build and nurture these skills? We do not have a master plan but rather an optimistic hypothesis: if the organization invests heavily in hands-on learning opportunities for staff and mangers over the next four years, then the investments in a dedicated innovation team will no longer be required. If the next iteration of UNDP’s Strategic Plan dedicates resources and political will to build skills that can respond to this VUCA world, the UNDP offices of 2021 will have strong iteration and horizon scanning capacities.
In Asia-Pacific, we are testing an intervention to further develop these four core skills. In 2015 we launched the “Innovation Ambassadors” programme, appointing colleagues from 14 countries as ambassadors. They have all pushed innovation in their Country Offices over the last two years by testing new ideas and technologies, creating new partnerships and managed to inspire other colleagues to take up innovative approaches.
We brought these ambassadors together for one week with our innovation leads and partners from Nesta to learn the fundamentals of social innovation, and how to conduct portfolio scans of programmes and advise colleagues on innovation. The last two days were hands-on, enabling the ambassadors to work with programme teams from the UNDP Sri Lanka office on embedding innovation in new and ongoing programmes across all thematic areas. By undertaking horizon scans and practicing the inspiration function as well as diagnosis skills, together with experts who gave immediate feedback, our champions were able to learn by doing.
Currently we are designing other forms of capacity-building programmes to enable colleagues to use the Hacker Kit as a vehicle to strengthen their innovation skills and initiate new experiments.
Moving innovation to the core of an organization means making learning part of the brand. It means moving from an ‘answer delivery system’ to a ‘solutions generating system.’
Innovation as we approach it, means iterative design, based on early learning. “Rather than thinking of strategy as a single plan built on predictions of the future, we should think of strategy as a portfolio of experiments that competes and evolves over time” as Eric Beinhocker puts it.
Citizen EngagementDevelopmentDigital and Technology ModernisationHuman ResourcesLeadershipOrganisational DesignPublic ServiceReframing Rules and regulationsSystems Change
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REPUBLIC OF BULGARIA
National statistical institute
HomeStatistical dataProducts and Services Release Calendar List of the Standard Statistical Indicators INFOSTAT - Information System for online requests for statistical information Information Request IS Foreign trade Digital library Statistical Classifications and Registries Metadata and Methodology Quality reports Publications ESDS Help Desk User satisfaction Dissemination DataBase - SDMX 2.1 Referent InfrastructureLegal Basis Bulgarian Legal Basis European Legal Basis Strategies and Assessments Access to Public Information Protection of Statistical SecrecyAbout NSI Information Security Management Policy Statement of the NSI NSI in Brief National Statistical System Structure Quality International Cooperation
Statistical data ›
Business statistics ›
Investments ›
Expenditure on acquisition of tangible fixed assets ›
Annual data ›
Expenditure on acquisition of tangible fixed assets by statistical regions
Use IS Infostat for preceding years
Metadata and methodology
EXPENDITURE ON ACQUISITION OF TANGIBLE FIXED ASSETS BY ECONOMIC ACTIVITY GROUPINGS AND STATISTICAL REGIONS IN 2018
(Thousand Levs)
Economic activity groupings(A10)
Statistical regions
Severo-zapaden
Severen tsentralen
Severo-iztochen
Yugo-iztochen
Yugo-zapaden
Yuzhen tsentralen
Total 19 249 299 1 055 011 1 458 559 2 247 188 2 474 456 8 921 198 3 092 887
of wich: with foreign ownership more than 50% 4 400 161 81 850 219 058 377 283 530 629 2 606 591 584 750
Agriculture, forestry and fishing 1 622 082 299 125 330 286 324 205 289 510 162 576 216 380
Industry (except Construction) 5 729 893 408 713 526 924 726 822 983 093 1 747 459 1 336 882
Construction 1 503 061 42 596 62 973 175 772 206 960 774 496 240 264
Wholesale and retail trade, transport, accomodation and food service activities 4 910 272 174 400 309 552 588 835 595 388 2 545 253 696 844
Information and communication 554 651 4 190 9 468 21 803 11 936 485 761 21 493
Financial and insurance activities 447 343 637 2 475 14 691 4 870 417 633 7 037
Real estate activities 2 019 271 43 528 46 652 180 201 146 767 1 352 976 249 147
Professional, scientific, technical, administration and support service activities 1 197 842 27 745 71 014 104 193 58 242 832 116 104 532
Public administration, defence, education, human health and social work activities 980 047 45 461 85 512 68 370 139 693 459 079 181 932
Arts, entertainment and recreation; other activities 284 837 8 616 13 703 42 296 37 997 143 849 38 376
Expenditure on Acquisition of Tangible Fixed Assets - annually survey - Expenditure on acquisition of tangible fixed assets
Contact organisation unit
"Annual Business Statistics"
Irena Meshulam-Yanakieva
Contact person function
Contact mail address
2, P. Volov Street, 1038 Sofia
Contact fax number
Metadata update
Metadata last certified
Metadata last posted
Metadata last update
Statistical presentation
The expenditure on acquisition of tangible fixed assets and the acquired tangible fixed assets are indicators, which provide information about the investment activity of all economic sectors.
· Classification of Economic Activities (CEA-2008, for international use NACE.BG-2008) - in force since 01.01.2008;
· National Classification of Economic Activities (NCEA-2003, for international use NACE.BG-2003) - in force till 31.12.2007;
· Classification of Types of Construction (CC);
· Classification of territorial units for statistical purposes in Bulgaria (NUTS).
Sector coverage
The statistical survey covers all economic sectors - non-financial enterprises, finance and insurance companies, government administration (bodies of the legislative, executive and judicial branches, local self-government bodies and administration, autonomous state institutions) and non-profit organisations.
Statistical concepts and definitions
The expenditure on acquisition of tangible fixed assets during the period under review include the actual costs: land purchase and building construction, construction equipment and mechanisms through order and produced by own account, for delivery and installation of tangible fixed assets, for machinery, equipment and means of transport, for geological and hydrological prospecting, for research and design related to construction and other expenditure, connected with acquiring tangible fixed assets.
The current maintenance cost of existing tangible fixed assets is not included in the volume of expenditure on acquisition of tangible fixed assets.
The acquired tangible fixed assets during the period under review include the value of tangible fixed assets, acquired by the enterprise through construction (after commissioning under the established regulations of the Ministry of Regional Development and Public Works) and by purchase.
Statistical unit
The basic unit of observation is the enterprise.
The enterprise is the smallest organisation unit producing goods or services which makes its own business decisions. The enterprise carries out one or more activities at one or more locations. The enterprise may be an independent legal unit.
Another statistical unit of observation is a local unit which is the separate part of the enterprise (workshop, factory, warehouse, office, store, etc.). It is located throughout the country, carries out one or more activities and has at least one employee (even part-time). The data from local units are completed by the enterprise in the form ?Information for local units?, as an integral part of its annual report and is used for calculation the regional SBS data.
Statistical population
The survey is exhaustive and the statistical population includes all non-financial enterprises non-compiling balance sheets, non-financial enterprises compiling balance sheets, non-profit organizations, insurance companies, investment companies, health assurance companies, pension funds and budgetary enterprises and banks.
Reference area
The data refer to the activities of enterprises which perform expenditure on acquisition of tangible fixed assets and the acquired tangible fixed assets in the territory of a country.
2000 - the last reference year.
Base period
Thousand BGN
Institutional mandate
Legal acts and other agreements
European SBS Regulations:
· Regulation (EC) № 295/2008 of 11 March 2008 concerning SBS (recast);
· Regulation (EC) № 250/2009 of 11 March 2009 - definition of characteristics and technical format for the transmission of SBS data;
· Regulation (EC) № 251/2009 of 11 March 2009 - the series of data for SBS;
· Regulation (EC) № 223/2009 of 11 March 2009 - statistical confidentiality and transmission of confidential data to Eurostat;
· Regulation (EC) № 275/2010 of 30 March 2010 - criteria for the evaluation of the quality of SBS data;
· Regulation (EC) № 1893/2006 of 20 December 2006 - establishing NACE.BG-2008;
· Regulation (EC) № 58/97 of 20 December 1996 - concerning SBS;
· Regulation (EC) № 2700/98 of 17 December 1998 - definition of characteristics, amended by Regulation (EC) № 1670/2003 of 1 September 2003;
· Regulation (EC) № 2701/98 of 17 December 1998 - the series of data for SBS, amended by Regulation (EC) № 1669/2003 of 1 September 2003;
· Regulation (EC) № 2702/98 of 17 December 1998 - technical format for the transmission of SBS data, amended by Regulation (EC) № 1668/2003 of 1 September 2003;
· Regulation (EC) № 1618/1999 of 23 July 1999 - criteria for the evaluation of the quality of SBS data;
· Regulation (EC) № 1614/2002 of 6 September 2002 - amending the definitions, data series and technical format.
Bulgarian legislation:
· Law on Statistics;
· National Statistical Programmer;
· Accounting and tax legislation.
Confidentiality - policy
Regulation (EC) № 223/2009 of 11 March 2009 defines common criteria for protection of confidential data and methods for sending the information to and its use by Eurostat. The Law on Statistics ensures the protection of statistical confidentiality and the use of individual data of enterprises for statistical purposes only.
Confidentiality - data treatment
The individual (primary) data are confidential according to the Law on Statistics and European legislation. To ensure their protection and inability to be identified, the aggregated indicators are also defined as confidential when:
· Criterion A - the indicator is calculated from one or two enterprises;
· Criterion B - one enterprise forms 85% or more of the total value of this indicator.
The data are published in accordance with the deadline specified in the Release Calendar presenting the results of the statistical surveys carried out by the National Statistical Institute.
Release calendar access
The calendar is available on the NSI website: http://www.nsi.bg/en/node/480
Data are published on the NSI website and are available to all users of statistical information.
Frequency of dissemination
Accessibility and clarity
Regular press release of preliminary data.
· Statistical Yearbook;
· Statistical Reference Book;
· Regions, Districts and Municipalities in the Republic of Bulgaria.
On-line database
The data on Expenditure on Acquisition of Tangible Fixed Assets are available to all users of the NSI website under the heading Buisness statistics - Statistical data - Investments - Expenditure on acquisition of tangible fixed assets - Annual data: http://www.nsi.bg/en/node/6204
Micro-data access
Information service on request, according to the Rules for dissemination of statistical products and services of NSI.
Documentation on methodology
Eurostat's methodological manual concerning SBS data, based on the European legislation on SBS and the harmonised national legislation in the same field: http://www.nsi.bg/sites/default/files/files/metadata/Investments_Method_2.2_en.pdf
Quality documentation
Data quality of expenditure on acquisition of tangible fixed assets is reflected in the annual SBS Quality report.
This includes the improvement of the on-line based information system 'Business statistics', which ensures strict arithmetical and logical input control. The additional output control is made when are registered the big differences in the value of given indicator between two consecutive years or in comparison with the results of other statistical surveys in NSI - Short-term statistics.
This is made in accordance with the standard criteria for assessing the quality - relevance, accuracy and reliability, timeliness, comparability and coherence.
The main users of data are:
· Eurostat and other international organizations;
· Interested state institutions under signed agreements;
· Research institutes, universities, economic analysts and students;
· Private non-governmental organizations, agencies, associations, media, etc.;
· Directorates and departments in the NSI.
User satisfaction
There has been no study of user satisfaction, but no case of outstanding requests for information.
Full compliance with the Bulgarian and European legislation.
Accuracy and reliability
Overall accuracy
The statistical data have good accuracy and reliability.
The survey is exhaustive and there are no sampling errors.
Non-sampling error
Timeliness and punctuality
The deadlines for the publication of SBS data on national level are t+8 months for the preliminary data and t+11 months for the final data. In the Eurostat the preliminary and the final SBS data will be sent after t +10 months and t +18 months respectively, where t is the reference year.
The deadlines under item 15.1 are strictly followed.
Coherence and comparability
Comparability - geographical
For the country data are geographical comparable.
Comparability - over time
The comparability of the data is limited by the use of different classifications of economic activities (NACE.BG-2008 and NACE.BG-2003), if there is a difference in the scope of the activity.
Coherence - cross domain
Coherence - internal
Cost and burden
NSI of Bulgaria is making extraordinary efforts to reduce the respondents' burden. An example is the signed agreement called "Single Entry Point" between NSI and the National Revenue Agency for a single providing of the annual reports and using the data from both institutions. Developed by NSI on-line based information system "Business Statistics" and ensured methodological and technical assistance to respondents during the reporting campaign are highly appreciated by respondents and help to reduce their workload.
Data revision
Data revision - policy
The National policy, as well as Eurostat's, allows the revision of already published data if there are serious reasons.
Data revision - practice
The revised data replace the already published data as soon as possible after the revision is made.
Statistical processing
Source data
Information on the expenditure on acquisition of tangible fixed assets is derived from "Questionnaire about expenditure on acquisition of tangible fixed assets" included in the annual report of enterprises. The enterprises? bookkeeping reports are the source of information for data filling in the statistical questionnaires.
Frequency of data collection
Annually.
The survey is exhaustive for all economic sectors.
Data validation is made by additional logical input control and comparison between the output data and the results of the previous year and other surveys, carried out by NSI.
The survey is exhaustive and further data evaluation is not made.
Download in SDMX 2.1 file format: Expenditure on Acquisition of Tangible Fixed Assets - annually survey - Expenditure on acquisition of tangible fixed assets
Metadata Structure Definition in SDMX 2.1: ESMS_MSD+BNSI+2.0+SDMX.2.1.xml
Foreign Direct Investments and Expenditure on Acquisition of Tangible Fixed Assets in 2018 (preliminary data)
Friday, 30 August 2019 - 11:00
According to preliminary data the foreign direct investments in the non-financial sector as of 31.12.2018 amounted to 25 454 million Euro at current prices.
According to preliminary data in 2018 the expenditure on acquisition of tangible fixed assets in all sectors of the economy amounted to 19 267 million BGN at current prices.
Investments2018p_en_G7IU3SB.pdf
According to preliminary data the foreign direct investments in the non-financial sector as of 31.12.2017 amounted to 24 366 million Euro, which was 3.6% more compared to 2016.
Investments2017p_en_FZ93BH3.pdf
Thursday, 31 August 2017 - 11:00
According to preliminary data the foreign direct investments in the non-financial sector as of 31.12.2016 amounted to 23 491 million Euro, which is 1.4% more compared to 2015.
Investments2016p_en_B9T6252.pdf
Wednesday, 31 August 2016 - 11:00
Investments2015p_en_9H0VM6I.pdf
Monday, 31 August 2015 - 11:00
According to preliminary data the foreign direct investments in the non-financial sector as of 31.12.2014 amounted to 21 953 million Euro, which is 5.9% less compared to 2013.
Investments2014p_en_3G9VN2P.pdf
Foreign Direct Investments and Expenditure on Acquisition of Tangible Fixed Assets, 2013
Investments2013p_en_68ZK7H8.pdf
According to preliminary data the foreign direct investments in the non-financial sector as of 31.12.2012 amounted to 21 623 million Euro and fell by 0.1% compared to 2011.
Investments2012p_en_4SRIIUE.pdf
According to preliminary data the foreign direct investments in the non-financial sector as of 31.12.2011 amounted to EUR 21 616 Million and fell by 2.2% compared to 2010.
Investments2011p_en.pdf
Tuesday, 30 August 2011 - 11:00
According to preliminary data the foreign direct investments in non-financial sector as of 31.12.2010 amounted to EUR 22 119 million or by 8.2% more as compared to 2009.
According to preliminary data in 2010 the actual expenditure on acquisition of tangible fixed assets in all sectors of the economy reached 16 317 million BGN and fell by 23.3% than the previous year.
Thursday, 30 September 2010 - 11:00
According to preliminary data the foreign direct investments in non-financial sector as of 31.12.2009 amounted to 20 438.5 million euro or by 6.5% more as compared to 2008.
In 2009, according to preliminary data the actual expenditure on acquisition of tangible fixed assets in all sectors of the economy was 21 294.9 million levs or decreased by 29.7% in constant prices compared to 2008.
Investments2009_en.pdf
Key Indicators for Bulgaria (as of 31.12.2019)
Statistical Yearbook 2018 in infographics
The National Statistical Institute presents to your attention the 86th edition of the Statistical Yearbook of the Republic of Bulgaria in infographics.
In 2018, for the first time, we presented the results of the statistical surveys through graphics, images and other visualization tools, which resulted in a positive response among a wide range of users. We believe that this modern way of presenting statistical information will trigger the interest in those who for the first time encounter the meaning of numbers revealing important aspects of socio-economic life.
Statistical Reference Book 2019
The National Statistical Institute presents to users of statistical information the annual publication - Statistical Reference Book 2019 in English.
The Statistical Reference Book presents topical information on the demographic processes as well as the economic, social and cultural development of the Republic of Bulgaria for the 2015 - 2018 period.
Statistical Reference Book 2019 (Bulgarian version)
The National Statistical Institute presents to users of statistical information the annual publication - Statistical Reference Book 2019 in Bulgarian.
Statistical Yearbook 2018
The National Statistical Institute (NSI) has the pleasure to present to the attention of national and foreign users of statistical information the 86th edition of the ‘Statistical Yearbook of the Republic of Bulgaria’ in printed and electronic format.
It provides current statistical information about the demographic, economic and social development of the country for 2012 - 2017 in different territorial and classification aggregations and breakdowns.
About NSI
Annual Business Statistics
Business Surveys
Foreign direct investments
Expenditure on acquisition of tangible fixed assets
Expenditure on acquisition of tangible fixed assets by economic activity groupings
R&D, Innovations and Information Society
Short-term Business Statistics
Demographic and social statistics
Macroeconomic statistics
Regional statistics and indicators for monitoring
2, P. Volov Str.
Phone: (+359 2) 9857 111
Production in construction up by 0.7% in euro area
Annual inflation up to 1.3% in the euro area
1 in 4 EU citizens avoided providing personal information to social or professional networking services due to security concerns
© 2020 | National Statistical Institute
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DRUG CLASS : Corticosteroids-Inhalation/Nasal; Topical Steroids
BRAND NAMES : Atemur Mite (Germany); Cutivate (US); Flixonase (Bahamas, Barbados, Belize, Bermuda, Curacao, Guyana, Jamaica, Netherland-Antilles, Puerto-Rico, Surinam, Trinidad, Denmark, Bulgaria, France, Hungary, Russia, Italy, Turkey, Netherlands, Finland, England, Czech-Republic, Austria, Colombia, Mexico, Peru, Costa-Rica, Dominican-Republic, El-Salvador, Guatemala, Honduras, Nicaragua, Panama, Hong-Kong, Indonesia, Korea, Malaysia, Taiwan, Thailand, Israel); Flixonase Nasal Spray (New-Zealand); Flixotide (Bahamas, Barbados, Belize, Bermuda, Curacao, Guyana, Jamaica, Netherland-Antilles, Puerto-Rico, Surinam, Trinidad, Denmark, England, Finland, France, Austria, Czech-Republic, Bulgaria, Hungary, Russia, Italy, Turkey, Netherlands, Mexico, Peru, Hong-Kong, Indonesia, Korea, Philippines, Taiwan, Thailand, South-Africa, Israel); Flixotide Disk (New-Zealand); Flixotide Disks (Australia); Flixotide Inhaler (Australia); Flonase (US); Flonase Aq (US); Flovent (US); Flunase (US); Flutide (Germany, Japan); Flutivate (Germany, Norway); Zoflut (US); (International brand names outside U.S. in italics)
COST OF THERAPY : $ 210.69 (Rhinitis; Spray; 0.05 mg/inh; 0.2 gm/day; 365 days)
Fluticasone Propionate (Inhalation)
Fluticasone propionate is a corticosteroid having the chemical name S-(fluoromethyl)6alpha,9-difluoro-11beta, 17-dihydroxy-16alpha-methyl-3-oxoandrosta-1,4-diene-17beta-carbothioate, 17-propionate.
Fluticasone propionate is a white to off-white powder with a molecular weight of 500.6, and the empirical formula is C25H31F3O5S. It is practically insoluble in water, freely soluble in dimethyl sulfoxide and dimethylformamide, and slightly soluble in methanol and 95% ethanol.
Flovent Rotadisk 50 mug, 100 mug, and 250 mug contain a dry powder presentation of fluticasone propionate intended for oral inhalation only. Each double-foil Rotadisk contains four blisters. Each blister contains a mixture of 50, 100, or 250 mug of microfine fluticasone propionate blended with lactose to a total weight of 25 mg. The contents of each blister are inhaled using a specially designed plastic device for inhaling powder called the Diskhaler. After a fluticasone propionate Rotadisk is loaded into the Diskhaler, a blister containing medication is pierced and the fluticasone propionate is dispersed into the air stream created when the patient inhales through the mouthpiece.
The amount of drug delivered to the lung will depend on patient factors such as inspiratory flow. Under standardized in vitro testing, Flovent Rotadisk delivers 44, 88, or 220 mug of fluticasone propionate from Flovent Rotadisk 50 mug, 100 mug, or 250 mug, respectively, when tested at a flow rate of 60 L/min for 3 seconds. In adult and adolescent patients with asthma, mean peak inspiratory flow (PIF) through the Diskhaler was 123 L/min (range, 88 to 159 L/min), and in pediatric patients 4 to 11 years of age with asthma, mean PIF was 110 L/min (range, 43 to 175 L/min).
Inhalation Aerosol
Flovent 44 mug, 110 mug, and 220 mug inhalation aerosol are pressurized, metered-dose aerosol units intended for oral inhalation only. Each unit contains a microcrystalline suspension of fluticasone propionate (micronized) in a mixture of two chlorofluorocarbon propellants (trichlorofluoromethane and dichlorodifluoromethane) with lecithin. Each actuation of the inhaler delivers 50, 125, or 250 mug of fluticasone propionate from the valve, and 44, 110, or 220 mug, respectively, of fluticasone propionate from the actuator.
CLINICAL PHARMACOLOGY :
Fluticasone propionate is a synthetic, trifluorinated corticosteroid with potent anti-inflammatory activity. In vitro assays using human lung cytosol preparations have established fluticasone propionate as a human glucocorticoid receptor agonist with an affinity 18 times greater than dexamethasone, almost twice that of beclomethasone-17-monopropionate (BMP), the active metabolite of beclomethasone dipropionate, and over three times that of budesonide. Data from the McKenzie vasoconstrictor assay in man are consistent with these results.
The precise mechanisms of fluticasone propionate action in asthma are unknown. Inflammation is recognized as an important component in the pathogenesis of asthma. Corticosteroids have been shown to inhibit multiple cell types (e.g., mast cells, eosinophils, basophils, lymphocytes, macrophages, and neutrophils) and mediator production or secretion (e.g., histamine, eicosanoids, leukotrienes, and cytokines) involved in the asthmatic response. These anti-inflammatory actions of corticosteroids may contribute to their efficacy in asthma.
Though highly effective for the treatment of asthma, corticosteroids do not affect asthma symptoms immediately. However, improvement following inhaled administration of fluticasone propionate can occur within 24 hours of beginning treatment, although maximum benefit may not be achieved for 1 to 2 weeks or longer after starting treatment. When corticosteroids are discontinued, asthma stability may persist for several days or longer.
The activity of fluticasone propionate inhalation powder and aerosol is due to the parent drug, fluticasone propionate. Studies using oral dosing of labeled and unlabeled drug have demonstrated that the oral systemic bioavailability of fluticasone propionate is negligible (<1%), primarily due to incomplete absorption and pre-systemic metabolism in the gut and liver. In contrast, the majority of the fluticasone propionate delivered to the lung is systemically absorbed. The systemic bioavailability of fluticasone propionate inhalation powder in healthy volunteers averaged about 13.5% of the nominal dose; the systemic bioavailability of fluticasone propionate inhalation aerosol in healthy volunteers averaged about 30% of the dose delivered from the actuator.
Peak plasma concentrations after a 1000-mug dose of fluticasone propionate inhalation powder ranged from 0.1 to 1.0 ng/ml; Peak plasma concentrations after an 880-mug inhaled dose of fluticasone propionate inhalation aerosol ranged from 0.1 to 1.0 ng/ml.
Following intravenous administration, the initial disposition phase for fluticasone propionate was rapid and consistent with its high lipid solubility and tissue binding. The volume of distribution averaged 4.2 L/kg. The percentage of fluticasone propionate bound to human plasma proteins averaged 91%. Fluticasone propionate is weakly and reversibly bound to erythrocytes. Fluticasone propionate is not significantly bound to human transcortin.
The total clearance of fluticasone propionate is high (average, 1093 ml/min), with renal clearance accounting for less than 0.02% of the total. The only circulating metabolite detected in man is the 17beta-carboxylic acid derivative of fluticasone propionate, which is formed through the cytochrome P450 3A4 pathway. This metabolite had approximately 2000 times less affinity than the parent drug for the glucocorticoid receptor of human lung cytosol in vitro and negligible pharmacological activity in animal studies. Other metabolites detected in vitro using cultured human hepatoma cells have not been detected in man.
Additional Information for Inhalation Powder Only : In a multiple-dose drug interaction study, coadministration of fluticasone propionate (500 mug twice daily) and erythromycin (333 mg three times daily) did not affect fluticasone propionate pharmacokinetics. In a drug interaction study, coadministration of fluticasone propionate (1000 mug) and ketoconazole (200 mg once daily) resulted in increased fluticasone propionate concentrations, a reduction in plasma cortisol AUC, and no effect on urinary excretion of cortisol.
Following intravenous dosing, fluticasone propionate showed polyexponential kinetics and had a terminal elimination half-life of approximately 7.8 hours. Less than 5% of a radiolabeled oral dose was excreted in the urine as metabolites, with the remainder excreted in the feces as parent drug and metabolites.
Formal pharmacokinetic studies using fluticasone propionate were not carried out in any special populations. In a clinical study using fluticasone propionate inhalation powder, trough fluticasone propionate plasma concentrations were collected in 76 males and 74 females after inhaled administration of 100 and 500 mug twice daily. Full pharmacokinetic profiles were obtained from seven female patients and 13 male patients at these doses, and no overall differences in pharmacokinetic behavior were found.
Additional Information for Inhalation Powder Only : Plasma concentrations of fluticasone propionate were measured 20 and 40 minutes after dosing from 29 children aged 4 to 11 years who were taking either 50 or 100 mug twice daily of fluticasone propionate inhalation powder. Plasma concentration values ranged from below the limit of quantitation (25 pg/ml) to 117 pg/ml (50-mug dose) or 154 pg/ml (100-mug dose). In a study with adults taking the 100-mug twice-daily dose, the plasma concentrations observed ranged from below the limit of quantitation to 73.1 pg/ml. The median fluticasone propionate plasma concentrations for the 100-mug dose in children was 58.7 pg/ml; in adults the median plasma concentration was 39.5 pg/ml.
To confirm that systemic absorption does not play a role in the clinical response to inhaled fluticasone propionate, a double-blind clinical study comparing inhaled and oral fluticasone propionate was conducted. Doses of 100 and 500 mug twice daily of fluticasone propionate inhalation powder were compared to oral fluticasone propionate, 20,000 mug given once daily, and placebo for 6 weeks. Plasma levels of fluticasone propionate were detectable in all three active groups, but the mean values were highest in the oral group. Both doses of inhaled fluticasone propionate were effective in maintaining asthma stability and improving lung function while oral fluticasone propionate and placebo were ineffective. This demonstrates that the clinical effectiveness of inhaled fluticasone propionate is due to its direct local effect and not to an indirect effect through systemic absorption.
The potential systemic effects of inhaled fluticasone propionate on the hypothalamic-pituitary-adrenal (HPA) axis were also studied in asthma patients. Fluticasone propionate given by inhalation aerosol at doses of 220, 440, 660, or 880 mug twice daily was compared with placebo or oral prednisone 10 mg given once daily for 4 weeks. For most patients, the ability to increase cortisol production in response to stress, as assessed by 6-hour cosyntropin stimulation, remained intact with inhaled fluticasone propionate treatment. No patient had an abnormal response (peak less than 18 mug/dl for inhalation aerosol) after dosing with placebo or fluticasone propionate 220 mug twice daily. Ten percent (10%) to 16% of patients treated with fluticasone propionate at doses of 440 mug or more twice daily had an abnormal response as comparted to 29% of patients treated with prednisone.
Additional Information for Inhalation Powder Only : In clinical trials with fluticasone propionate inhalation powder, using doses up to and including 250 mug twice daily, occasional abnormal short cosyntropin tests (peak serum cortisol <18 mug/dl) were noted in patients receiving fluticasone propionate or placebo. The incidence of abnormal tests at 500 mug twice daily was greater than placebo. In a 2-year study carried out in 64 patients randomized to fluticasone propionate 500 mug twice daily or placebo, 1 patient receiving fluticasone propionate (4%) had an abnormal response to 6-hour cosyntropin infusion at 1 year; repeat testing at 18 months and 2 years was normal. Another patient receiving fluticasone propionate (5%) had an abnormal response at 2 years. No patient on placebo had an abnormal response at 1 or 2 years.
CLINICAL STUDIES :
Double-blind, parallel, placebo-controlled, U.S. clinical trials were conducted in 1197 adolescent and adult asthma patients to assess the efficacy and safety of fluticasone propionate inhalation powder in the treatment of asthma. Fixed doses of 50, 100, 250, and 500 mug twice daily were compared to placebo to provide information about appropriate dosing to cover a range of asthma severity. Asthmatic patients included in these studies were those not adequately controlled with beta-agonists alone, and those already maintained on daily inhaled corticosteroids. In these efficacy trials, at all doses, measures of pulmonary function (forced expiratory volume in 1 second [FEV1] and morning peak expiratory flow rate [AM PEFR]) were statistically significantly improved as compared with placebo. All doses were delivered by inhalation of the contents of one or two blisters from the Diskhaler twice daily.
A 12-week trial tested pulmonary function for two recommended dosages of fluticasone propionate inhalation powder (100 and 250 mug twice daily) and placebo in 331 adolescent and adult asthma patients (baseline FEV1 = 2.63 L/sec) inadequately controlled on bronchodilators alone. Because this trial used predetermined criteria for lack of efficacy, which caused more patients in the placebo group to be withdrawn, pulmonary function results at Endpoint, which is the last evaluable FEV 1 result and includes most patients’ lung function data, are also considered. Pulmonary function at both fluticasone propionate dosages improved significantly compared with placebo by the first week of treatment, and this improvement was maintained over the duration of the trial.
In a second clinical study of 75 patients, 500 mug twice daily was evaluated in a similar population. In this trial fluticasone propionate significantly improved pulmonary function as compared with placebo.
Another 12-week trial tested pulmonary function for two recommended dosages of fluticasone propionate inhalation powder (100 and 250 mug twice daily) and placebo in 342 adolescent and adult asthma patients (baseline FEV1 = 2.49 L/sec) already receiving daily inhaled corticosteroid therapy ( 336 mug/day of beclomethasone dipropionate or 800 mug/day of triamcinolone acetonide) in addition to as-needed albuterol and theophylline (38% of all patients). Because this trial also used predetermined criteria for lack of efficacy, which caused more patients in the placebo group to be withdrawn, pulmonary function results at Endpoint are included. Pulmonary function at both fluticasone propionate dosages improved significantly compared with placebo by the first week of treatment and the improvement was maintained over the duration of the trial.
In a second clinical study of 139 patients, treatment with 500 mug twice daily was evaluated in a similar patient population. In this trial fluticasone propionate significantly improved pulmonary function as compared with placebo.
In the four trials described above, all dosages of fluticasone propionate were efficacious; however, at higher dosages, patients were less likely to discontinue study participation due to asthma deterioration (as defined by predetermined criteria for lack of efficacy including lung function and patient-recorded variables such as AM PEFR, albuterol use, and nighttime awakenings due to asthma).
In a clinical trial of 96 severe asthmatic patients requiring chronic oral prednisone therapy (average baseline daily prednisone dose was 10 mg), fluticasone propionate given by inhalation aerosol at doses of 660 and 880 mug twice daily was evaluated. Both doses enabled a statistically significantly larger percentage of patients to wean successfully from oral prednisone as compared with placebo (69% of the patients on 660 mug twice daily and 88% of the patients on 880 mug twice daily as compared with 3% of patients on placebo). Accompanying the reduction in oral corticosteroid use, patients treated with fluticasone propionate had significantly improved lung function and fewer asthma symptoms as compared with the placebo group. These data were obtained from a clinical study using fluticasone propionate inhalation aerosol; no direct assessment of the clinical comparability of equal nominal doses for the inhalation powder and inhalation aerosol formulations in this population has been conducted.
Pediatric Experience : In a 12-week, placebo-controlled clinical trial of 263 patients aged 4 to 11 years inadequately controlled on bronchodilators alone (baseline morning peak expiratory flow = 200 L/min), fluticasone propionate inhalation powder doses of 50 and 100 mug twice daily significantly improved morning peak expiratory flow (28% and 34% change from baseline at endpoint, respectively) compared to placebo (11% change). In a second placebo-controlled, 52-week trial of 325 patients aged 4 to 11 years, approximately half of whom were receiving inhaled corticosteroids at baseline, doses of fluticasone propionate inhalation powder of 50 and 100 mug twice daily improved lung function by the first week of treatment, and the improvement continued over 1 year compared to placebo. In both studies, patients on active treatment were significantly less likely to discontinue treatment due to lack of efficacy.
Double-blind, parallel, placebo-controlled, U.S. clinical trials were conducted in 1818 adolescent and adult asthma patients to assess the efficacy and/or safety of fluticasone propionate inhalation aerosol in the treatment of asthma. Fixed doses ranging from 22 to 880 mug twice daily were compared to placebo to provide information about appropriate dosing to cover a range of asthma severity. Asthmatic patients included in these studies were those not adequately controlled with beta-agonists alone, those already maintained on daily inhaled corticosteroids, and those requiring oral corticosteroid therapy. In all efficacy trials, at all doses, measures of pulmonary function (forced expiratory volume in 1 second [FEV1] and morning peak expiratory flow rate [AM PEFR]) were statistically significantly improved as compared with placebo.
In two clinical trials of 660 asthmatic patients inadequately controlled on bronchodilators alone, fluticasone propionate administered by inhalation aerosol was evaluated at doses of 44 and 88 mug twice daily. Both doses of fluticasone propionate improved asthma control significantly as compared with placebo.
A 12-week trial produced results of pulmonary function tests for the recommended starting dosage of fluticasone propionate inhalation aerosol (88 mug twice daily) and placebo in asthma patients inadequately controlled on bronchodilators alone. Because this trial used predetermined criteria for lack of efficacy, which caused more patients in the placebo group to be withdrawn, pulmonary function results at Endpoint, which is the last evaluable FEV1 result and includes most patients’ lung function data, are also considered. Pulmonary function improved significantly with fluticasone propionate compared with placebo by the second week of treatment, and this improvement was maintained over the duration of the trial.
In clinical trials of 924 asthmatic patients already receiving daily inhaled corticosteroid therapy (doses of at least 336 mug/day of beclomethasone dipropionate) in addition to as-needed albuterol and theophylline (46% of all patients), fluticasone propionate inhalation aerosol doses of 22 to 440 mug twice daily were also evaluated. All doses of fluticasone propionate were efficacious when compared to placebo on major endpoints including lung function and symptom scores. Patients treated with fluticasone propionate were also less likely to discontinue study participation due to asthma deterioration (as defined by predetermined criteria for lack of efficacy including lung function and patient-recorded variables such as AM PEFR, albuterol use, and nighttime awakenings due to asthma).
Pulmonary function results were gathered from a 12-week clinical trial in asthma patients already receiving daily inhaled corticosteroid therapy (beclomethasone dipropionate 336 to 672 mug/day). The mean percent change from baseline in lung function results for fluticasone propionate inhalation aerosol dosages of 88, 220, and 440 mug twice daily and placebo are shown over the 12-week trial. Because this trial also used predetermined criteria for lack of efficacy, which caused more patients in the placebo group to be withdrawn, pulmonary function results at Endpoint are included. Pulmonary function improved significantly with fluticasone propionate compared with placebo by the first week of treatment, and the improvement was maintained over the duration of the trial. Analysis of the Endpoint results that adjusted for differential withdrawal rates indicated that pulmonary function significantly improved with fluticasone propionate compared with placebo treatment. Similar improvements in lung function were seen in the other two trials in patients treated with inhaled corticosteroids at baseline.
In a clinical trial of 96 severe asthmatic patients requiring chronic oral prednisone therapy (average baseline daily prednisone dose was 10 mg), fluticasone propionate inhalation aerosol doses of 660 and 880 mug twice daily were evaluated. Both doses enabled a statistically significantly larger percentage of patients to wean successfully from oral prednisone as compared with placebo (69% of the patients on 660 mug twice daily and 88% of the patients on 880 mug twice daily as compared with 3% of patients on placebo). Accompanying the reduction in oral corticosteroid use, patients treated with fluticasone propionate inhalation aerosol had significantly improved lung function and fewer asthma symptoms as compared with the placebo group.
INDICATIONS AND USAGE :
Fluticasone propionate is indicated for the maintenance treatment of asthma as prophylactic therapy (for inhalation powder, in patients 4 years of age and older). It is also indicated for patients requiring oral corticosteroid therapy for asthma. Many of these patients may be able to reduce or eliminate their requirement for oral corticosteroids over time.
Fluticasone propionate is NOT indicated for the relief of acute bronchospasm.
CONTRAINDICATIONS :
Fluticasone propionate is contraindicated in the primary treatment of status asthmaticus or other acute episodes of asthma where intensive measures are required.
Hypersensitivity to any of the ingredients of these preparations contraindicates their use.
WARNINGS :
Particular care is needed for patients who are transferred from systemically active corticosteroids to fluticasone propionate because deaths due to adrenal insufficiency have occurred in asthmatic patients during and after transfer from systemic corticosteroids to less systemically available inhaled corticosteroids. After withdrawal from systemic corticosteroids, a number of months are required for recovery of HPA function.
Patients who have been previously maintained on 20 mg or more per day of prednisone (or its equivalent) may be most susceptible, particularly when their systemic corticosteroids have been almost completely withdrawn. During this period of HPA suppression, patients may exhibit signs and symptoms of adrenal insufficiency when exposed to trauma, surgery, or infection (particularly gastroenteritis) or other conditions associated with severe electrolyte loss. Although fluticasone propionate inhalation powder and aerosol may provide control of asthma symptoms during these episodes, in recommended doses they supply less than normal physiological amounts of corticosteroid systemically and do NOT provide the mineralocorticoid activity that is necessary for coping with these emergencies.
During periods of stress or a severe asthma attack, patients who have been withdrawn from systemic corticosteroids should be instructed to resume oral corticosteroids (in large doses) immediately and to contact their physicians for further instruction. These patients should also be instructed to carry a warning card indicating that they may need supplementary systemic corticosteroids during periods of stress or a severe asthma attack.
Patients requiring oral corticosteroids should be weaned slowly from systemic corticosteroid use after transferring to fluticasone propionate inhalation powder or aerosol. In a clinical trial of 96 patients, prednisone reduction was successfully accomplished by reducing the daily prednisone dose by 2.5 mg on a weekly basis during transfer to inhaled fluticasone propionate. Successive reduction of prednisone dose was allowed only when lung function, symptoms, and as-needed beta-agonist use were better than or comparable to that seen before initiation of prednisone dose reduction. Lung function (FEV1 or AM PEFR), beta-agonist use, and asthma symptoms should be carefully monitored during withdrawal of oral corticosteroids. In addition to monitoring asthma signs and symptoms, patients should be observed for signs and symptoms of adrenal insufficiency such as fatigue, lassitude, weakness, nausea and vomiting, and hypotension.
Transfer of patients from systemic corticosteroid therapy to fluticasone propionate inhalation powder or aerosol may unmask conditions previously suppressed by the systemic corticosteroid therapy, e.g., rhinitis, conjunctivitis, eczema, and arthritis.
Persons who are on drugs that suppress the immune system are more susceptible to infections than healthy individuals. Chickenpox and measles, for example, can have a more serious or even fatal course in susceptible children or adults on corticosteroids. In such children or adults who have not had these diseases, particular care should be taken to avoid exposure. How the dose, route, and duration of corticosteroid administration affects the risk of developing a disseminated infection is not known. The contribution of the underlying disease and/or prior corticosteroid treatment to the risk is also not known. If exposed to chickenpox, prophylaxis with varicella zoster immune globulin (VZIG) may be indicated. If exposed to measles, prophylaxis with pooled intramuscular immunoglobulin (IG) may be indicated. (See complete prescribing information for IG and VZIG.) If chickenpox develops, treatment with antiviral agents may be considered.
Fluticasone propionate inhalation powder and aerosol are not to be regarded as bronchodilators and are not indicated for rapid relief of bronchospasm.
As with other inhaled asthma medications, bronchospasm may occur with an immediate increase in wheezing after dosing. If bronchospasm occurs following dosing with fluticasone propionate, it should be treated immediately with a fast-acting inhaled bronchodilator. Treatment with inhaled fluticasone propionate should be discontinued and alternative therapy instituted.
Patients should be instructed to contact their physicians immediately when episodes of asthma that are not responsive to bronchodilators occur during the course of treatment with fluticasone propionate inhalation powder or aerosol. During such episodes, patients may require therapy with oral corticosteroids.
During withdrawal from oral corticosteroids, some patients may experience symptoms of systemically active corticosteroid withdrawal, e.g., joint and/or muscular pain, lassitude, and depression, despite maintenance or even improvement of respiratory function.
Fluticasone propionate will often permit control of asthma symptoms with less suppression of HPA function than therapeutically equivalent oral doses of prednisone. Since fluticasone propionate is absorbed into the circulation and can be systemically active at higher doses, the beneficial effects of fluticasone propionate inhalation powder or aerosol in minimizing HPA dysfunction may be expected only when recommended dosages are not exceeded and individual patients are titrated to the lowest effective dose. A relationship between plasma levels of fluticasone propionate and inhibitory effects on stimulated cortisol production has been shown after 4 weeks of treatment with fluticasone propionate inhalation aerosol. Since individual sensitivity to effects on cortisol production exists, physicians should consider this information when prescribing fluticasone propionate inhalation powder or aerosol.
Because of the possibility of systemic absorption of inhaled corticosteroids, patients treated with these drugs should be observed carefully for any evidence of systemic corticosteroid effects. Particular care should be taken in observing patients postoperatively or during periods of stress for evidence of inadequate adrenal response.
It is possible that systemic corticosteroid effects such as hypercorticism and adrenal suppression may appear in a small number of patients, particularly at higher doses. If such changes occur, fluticasone propionate inhalation powder or aerosol should be reduced slowly, consistent with accepted procedures for reducing systemic corticosteroids and for management of asthma symptoms.
A reduction of growth velocity in children or teenagers may occur as a result of inadequate control of chronic diseases such as asthma or from use of corticosteroids for treatment. Physicians should closely follow the growth of children and adolescents taking corticosteroids by any route, and weigh the benefits of corticosteroid therapy against the possibility of growth suppression if growth appears slowed. Patients should be maintained on the lowest dose of inhaled corticosteroid that effectively controls their asthma.Additional Information for Inhalation Powder Only: A 52-week placebo-controlled study to assess the potential growth effects of fluticasone propionate inhalation powder at 50 and 100 mug twice daily was conducted in the U.S. in 325 prepubescent children (244 males and 81 females), 4 to 11 years of age. The mean growth velocities at 52 weeks observed in the intent-to-treat population were 6.32 cm/year in the placebo group (n = 76), 6.07 cm/year in the 50-mug group (n = 98), and 5.66 cm/year in the 100-mug group (n = 89). An imbalance in the proportion of children entering puberty between groups and a higher dropout rate in the placebo group due to poorly controlled asthma may be confounding factors in interpreting these data. A separate subset analysis of children who remained prepubertal during the study revealed growth rates at 52 weeks of 6.10 cm/year in the placebo group (n = 57), 5.91 cm/year in the 50-mug group (n = 74), and 5.67 cm/year in the 100-mug group (n = 79). The clinical significance of these growth data is not certain. In children 8.5 years of age, the mean age of children in this study, the range for expected growth velocity is: boys–3rd percentile = 3.8 cm/year, 50th percentile = 5.4 cm/year, and 97th percentile = 7.0 cm/year; girls–3rd percentile = 4.2 cm/year, 50th percentile = 5.7 cm/year, and 97th percentile = 7.3 cm/year. The effects of long-term treatment of children with inhaled corticosteroids, including fluticasone propionate, on final adult height are not known.
The long-term effects of fluticasone propionate in human subjects are not fully known. In particular, the effects resulting from chronic use of fluticasone propionate on developmental or immunologic processes in the mouth, pharynx, trachea, and lung are unknown. Some patients have received inhaled fluticasone propionate on a continuous basis for periods of 3 years or longer. In clinical studies with patients treated for nearly 2 years with inhaled fluticasone propionate, no apparent differences in the type or severity of adverse reactions were observed after long- versus short-term treatment.
Rare instances of glaucoma, increased intraocular pressure, and cataracts have been reported following the inhaled administration of corticosteroids, including fluticasone propionate.
In clinical studies with inhaled fluticasone propionate, the development of localized infections of the pharynx with Candida albicans has occurred. When such an infection develops, it should be treated with appropriate local or systemic (i.e., oral antifungal) therapy while remaining on treatment with fluticasone propionate inhalation powder or aerosol, but at times therapy with fluticasone propionate may need to be interrupted.
Inhaled corticosteroids should be used with caution, if at all, in patients with active or quiescent tuberculous infection of the respiratory tract; untreated systemic fungal, bacterial, viral, or parasitic infections; or ocular herpes simplex.
Eosinophilic Conditions
In rare cases, patients on inhaled fluticasone propionate may present with systemic eosinophilic conditions, with some patients presenting with clinical features of vasculitis consistent with Churg-Strauss syndrome, a condition that is often treated with systemic corticosteroid therapy. These events usually, but not always, have been associated with the reduction and/or withdrawal of oral corticosteroid therapy following the introduction of fluticasone propionate. Cases of serious eosinophilic conditions have also been reported with other inhaled corticosteroids in this clinical setting. Physicians should be alert to eosinophilia, vasculitic rash, worsening pulmonary symptoms, cardiac complications, and/or neuropathy presenting in their patients. A causal relationship between fluticasone propionate and these underlying conditions has not been established (see ADVERSE REACTIONS).
Patients being treated with fluticasone propionate should receive the following information and instructions. This information is intended to aid them in the safe and effective use of this medication. It is not a disclosure of all possible adverse or intended effects.
Patients should use fluticasone propionate at regular intervals as directed. Results of clinical trials indicated significant improvement may occur within the first day or two of treatment; however, the full benefit may not be achieved until treatment has been administered for 1 to 2 weeks or longer. The patient should not increase the prescribed dosage but should contact the physician if symptoms do not improve or if the condition worsens.
Patients should be warned to avoid exposure to chickenpox or measles and, if they are exposed, to consult their physicians without delay.
For the proper use of fluticasone propionate inhalation powder or aerosol and to attain maximum improvement, the patient should read and follow carefully the accompanying Patient’s Instructions for Use.
Carcinogenesis, Mutagenesis, and Impairment of Fertility
Fluticasone propionate demonstrated no tumorigenic potential in studies of oral doses up to 1000 mug/kg (approximately 2 times the maximum recommended daily inhalation dose in adults [and for powder approximately 10 times the maximum recommended daily inhalation dose in children on a mug/m2 basis]) for 78 weeks in the mouse or inhalation of up to 57 mug/kg (approximately ¼ the maximum recommended daily inhalation dose in adults [and for powder comparable to the maximum recommended daily inhalation dose in children] on a mug/m2 basis) for 104 weeks.
Fluticasone propionate did not induce gene mutation in prokaryotic or eukaryotic cells in vitro . No significant clastogenic effect was seen in cultured human peripheral lymphocytes in vitro or in the mouse micronucleus test when administered at high doses by the oral or subcutaneous routes. Furthermore, the compound did not delay erythroblast division in bone marrow.
No evidence of impairment of fertility was observed in reproductive studies conducted in rats dosed simultaneously with up to 50 mug/kg (approximately 1/5 [for powder] and ¼ [for aerosol] the maximum recommended daily inhalation dose in adults on a mug/m2 basis) in males and females. However, prostate weight was significantly reduced in rats.
Pregnancy, Teratogenic Effects, Pregnancy Category C
Subcutaneous studies in the mouse and rat at 45 and 100 mug/kg, respectively, (approximately 1/10 and 1/3 [for inhalation powder; ½ for inhalation aerosol] the maximum recommended human daily inhalation dose based on a mug/m2 respectively), revealed fetal toxicity characteristic of potent corticosteroid compounds, including embryonic growth retardation, omphalocele, cleft palate, and retarded cranial ossification.
In the rabbit, fetal weight reduction and cleft palate were observed following subcutaneous doses of 4 mug/kg (approximately 1/30 [for inhalation powder] and 1/25 [for inhalation aerosol] the maximum recommended human daily inhalation dose based on mug/m2). However, following oral administration of up to 300 mug/kg (approximately 2 times [for inhalation powder] and 3 times [for aerosol] the maximum human daily inhalation dose based on mug/m2) of fluticasone propionate to the rabbit, there were no maternal effects nor increased incidence of external, visceral, or skeletal fetal defects. No fluticasone propionate was detected in the plasma in this study, consistent with the established low bioavailability following oral administration (see CLINICAL PHARMACOLOGY).
Fluticasone propionate crossed the placenta (less than 0.008% of the administered dose for inhalation aerosol) following oral administration of 100 mug/kg to rats or 300 mug/kg to rabbits (approximately 1/3 and 2 times [for inhalation powder] and ½ and 3 times [for inhalation aerosol], respectively, the maximum recommended daily inhalation dose in adults on a mug/m2 basis).
There are no adequate and well-controlled studies in pregnant women. Fluticasone propionate should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Experience with oral corticosteroids since their introduction in pharmacologic, as opposed to physiologic, doses suggests that rodents are more prone to teratogenic effects from corticosteroids than humans. In addition, because there is a natural increase in corticosteroid production during pregnancy, most women will require a lower exogenous corticosteroid dose and many will not need corticosteroid treatment during pregnancy.
It is not known whether fluticasone propionate is excreted in human breast milk. Subcutaneous administration of 10 mug/kg tritiated drug to lactating rats (approximately 1/25 [for inhalation powder] and 1/20 [for inhalation aerosol] the maximum recommended daily inhalation dose on a mug/m2 basis) resulted in measurable radioactivity in milk (for inhalation aerosol, both plasma and milk). Because other corticosteroids are excreted in human milk, caution should be exercised when fluticasone propionate inhalation powder or aerosol is administered to a nursing woman.
Inhalation Powder : Two hundred fourteen (214) patients 4 to 11 years of age and 142 patients 12 to 16 years of age were treated with fluticasone propionate inhalation powder in U.S. clinical trials. The safety and effectiveness of fluticasone propionate inhalation powder in children below 4 years of age have not been established.
Inhaled corticosteroids, including fluticasone propionate, may cause a reduction in growth in children and adolescents (see PRECAUTIONS). If a child or adolescent on any corticosteroid appears to have growth suppression, the possibility that they are particularly sensitive to this effect of corticosteroids should be considered. Patients should be maintained on the lowest dose of inhaled corticosteroid that effectively controls their asthma.
Inhalation Aerosol : One hundred thirty-seven (137) patients between the ages of 12 and 16 years were treated with fluticasone propionate inhalation aerosol in the U.S. pivotal clinical trials. The safety and effectiveness of fluticasone propionate inhalation aerosol in children below 12 years of age have not been established. Oral corticosteroids have been shown to cause a reduction in growth velocity in children and teenagers with extended use. If a child or teenager on any corticosteroid appears to have growth suppression, the possibility that they are particularly sensitive to this effect of corticosteroids should be considered (see PRECAUTIONS).
Geriatric Use
One hundred seventy-three (173) [574 for inhalation aerosol] patients 65 years of age or older have been treated with fluticasone propionate inhalation powder and aerosol in U.S. and non-U.S. clinical trials. There were no differences in adverse reactions compared to those reported by younger patients.
DRUG INTERACTIONS :
Inhalation Powder Only
In a placebo-controlled, crossover study in eight healthy volunteers, coadministration of a single dose of fluticasone propionate (1000 mug) with multiple doses of ketoconazole (200 mg) to steady state resulted in increased mean fluticasone propionate concentrations, a reduction in plasma cortisol AUC, and no effect on urinary excretion of cortisol. This interaction may be due to an inhibition of the cytochrome P450 3A4 isoenzyme system by ketoconazole, which is also the route of metabolism of fluticasone propionate. Care should be exercised when fluticasone propionate is coadministered with long-term ketoconazole and other known cytochrome P450 3A4 inhibitors.
ADVERSE REACTIONS :
In TABLE 1, the incidence of common adverse experiences () is based upon six placebo-controlled clinical trials in which 1384 patients 4 years of age (520 females and 864 males) previously treated with as-needed bronchodilators and/or inhaled corticosteroids were treated with fluticasone propionate inhalation powder (doses of 50 to 500 mug twice daily for up to 12 weeks) or placebo.
TABLE 1 Overall Adverse Experiences With >3% Incidence on Fluticasone Propionate in Controlled Clinical Trials With Inhalation Powder in Patients 4 Years Previously Receiving Bronchodilators and/or Inhaled Corticosteroids
Fluticasone Propionate Inhalation Powder Twice Daily
50 mug
100 mug
Adverse Event
% (n=438)
Dysphonia
Upper respiratory infection
Back problems
Average Duration of Exposure (Days)
TABLE 1 includes all events (whether considered drug-related or nondrug-related by the investigator) that occurred at a rate of over 3% in any of the fluticasone propionate inhalation powder groups and were more common than in the placebo group. In considering these data, differences in average duration of exposure should be taken into account.
These adverse reactions were mostly mild to moderate in severity, with <2% of patients discontinuing the studies because of adverse events. Rare cases of immediate and delayed hypersensitivity reactions, including rash and other rare events of angioedema and bronchospasm, have been reported.
Other adverse events that occurred in these clinical trials using fluticasone propionate inhalation powder with an incidence of 1% to 3% and which occurred at a greater incidence than with placebo were:
Ear, Nose, and Throat : Otitis media, tonsillitis, nasal discharge, earache, laryngitis, epistaxis, sneezing.
Eye : Conjunctivitis.
Gastrointestinal : Abdominal pain, viral gastroenteritis, gastroenteritis/colitis, abdominal discomfort.
Miscellaneous : Injury.
Mouth and Teeth : Mouth irritation.
Musculoskeletal : Sprain/strain, pain in joint, disorder/symptoms of neck, muscular soreness, aches and pains.
Neurological : Migraine, nervousness.
Respiratory : Chest congestion, acute nasopharyngitis, dyspnea, irritation due to inhalant.
Skin : Dermatitis, urticaria.
Urogenital : Dysmenorrhea, candidiasis of vagina, pelvic inflammatory disease, vaginitis/vulvovaginitis, irregular menstrual cycle.
There were no clinically relevant differences in the pattern or severity of adverse events in children compared with those reported in adults.
Fluticasone propionate inhalation aerosol (660 or 880 mug twice daily) was administered for 16 weeks to asthmatics requiring oral corticosteroids. Adverse events reported more frequently in these patients compared to patients not on oral corticosteroids included sinusitis, nasal discharge, oropharyngeal candidiasis, headache, joint pain, nausea and vomiting, muscular soreness, malaise/fatigue, and insomnia.
Observed During Clinical Practice : The following events have been identified during postapproval use of fluticasone propionate in clinical practice. Because they are reported voluntarily from a population of unknown size, estimates of frequency cannot be made. These events have been chosen for inclusion due to either their seriousness, frequency of reporting, causal connection to fluticasone propionate, or a combination of these factors.
Ear, Nose, and Throat : Aphonia, cough, hoarseness, laryngitis, and throat soreness and irritation.
Endocrine and Metabolic : Cushingoid features, growth velocity reduction in children/adolescents, hyperglycemia, and weight gain.
Psychiatry : Agitation, aggression, depression, and restlessness.
Respiratory : Asthma exacerbation, bronchospasm, chest tightness, dyspnea, paradoxical bronchospasm, and wheezing.
Skin : Contusions, ecchymoses, and pruritus.
Eosinophilic Conditions : In rare cases, patients on inhaled fluticasone propionate may present with systemic eosinophilic conditions, with some patients presenting with clinical features of vasculitis consistent with Churg-Strauss syndrome, a condition that is often treated with systemic corticosteroid therapy. These events usually, but not always, have been associated with the reduction and/or withdrawal of oral corticosteroid therapy following the introduction of fluticasone propionate. Cases of serious eosinophilic conditions have also been reported with other inhaled corticosteroids in this clinical setting. Physicians should be alert to eosinophilia, vasculitic rash, worsening pulmonary symptoms, cardiac complications, and/or neuropathy presenting in their patients. A causal relationship between fluticasone propionate and these underlying conditions has not been established (see PRECAUTIONS: Eosinophilic Conditions).
The following incidence of common adverse experiences is based upon seven placebo-controlled U.S. clinical trials in which 1243 patients (509 female and 734 male adolescents and adults previously treated with as-needed bronchodilators and/or inhaled corticosteroids) were treated with fluticasone propionate inhalation aerosol (doses of 88 to 440 mug twice daily for up to 12 weeks) or placebo. (See TABLE 2.)
TABLE 2 Overall Adverse Experiences With >3% Incidence on Fluticasone Propionate in U.S. Controlled Clinical Trials With MDI in Patients Previously Receiving Bronchodilators and/or Inhaled Corticosteroids
Fluticasone Propionate Inhalation Aerosol Twice Daily
Placebo (n=475) %
88 mug (n=488) %
220 mug (n=95) %
440 mug(n=185) %
Nasal discharge
TABLE 2 includes all events (whether considered drug-related or nondrug-related by the investigator) that occurred at a rate of over 3% in the combined fluticasone propionate inhalation aerosol groups and were more common than in the placebo group. In considering these data, differences in average duration of exposure should be taken into account.
These adverse reactions were mostly mild to moderate in severity, with 2% of patients discontinuing the studies because of adverse events. Rare cases of immediate and delayed hypersensitivity reactions, including urticaria and rash and other rare events of angioedema and bronchospasm, have been reported.
Systemic glucocorticoid side effects were not reported during controlled clinical trials with fluticasone propionate inhalation aerosol. If recommended doses are exceeded, however, or if individuals are particularly sensitive, symptoms of hypercorticism, e.g., Cushing’s syndrome, could occur.
Other adverse events that occurred in these clinical trials using fluticasone propionate inhalation aerosol with an incidence of 1% to 3% and which occurred at a greater incidence than with placebo were:
Ear, Nose, and Throat : Pain in nasal sinus(es), rhinitis.
Eye : Irritation of the eye(s).
Gastrointestinal : Nausea and vomiting, diarrhea, dyspepsia and stomach disorder.
Miscellaneous : Fever.
Mouth and Teeth : Dental problem.
Musculoskeletal : Pain in joint, sprain/strain, aches and pains, pain in limb.
Neurological : Dizziness/giddiness.
Respiratory : Bronchitis, chest congestion.
Skin : Dermatitis, rash/skin eruption.
Urogenital : Dysmenorrhea.
In a 16-week study in asthmatics requiring oral corticosteroids, the effects of fluticasone propionate inhalation aerosol, 660 mug twice daily (n = 32) and 880 mug twice daily (n = 32), were compared with placebo. Adverse events (whether considered drug-related or nondrug-related by the investigator) reported by more than three patients in either fluticasone propionate group and which were more common with fluticasone propionate than placebo are shown below:
Ear, Nose, and Throat : Pharyngitis (9% and 25%); nasal congestion (19% and 22%); sinusitis (19% and 22%); nasal discharge (16% and 16%); dysphonia (19% and 9%); pain in nasal sinus(es) (13% and 0%); Candida-like oral lesions (16% and 9%); oropharyngeal candidiasis (25% and 19%).
Respiratory : Upper respiratory infection (31% and 19%); influenza (0% and 13%).
Other : Headache (28% and 34%); pain in joint (19% and 13%); nausea and vomiting (22% and 16%); muscular soreness (22% and 13%); malaise/fatigue (22% and 28%); insomnia (3% and 13%).
Observed During Clinical Practice : In addition to adverse events reported from clinical trials, the following events have been identified during postapproval use of fluticasone propionate in clinical practice. Because they are reported voluntarily from a population of unknown size, estimates of frequency cannot be made. These events have been chosen for inclusion due to either their seriousness, frequency of reporting, causal connection to fluticasone propionate, or a combination of these factors.
Ear, Nose, and Throat : Throat soreness and irritation, hoarseness, laryngitis, aphonia.
Endocrine and Metabolic : Cushingoid features, growth velocity reduction in children/adolescents, weight gain, hyperglycemia.
Psychiatry : Restlessness, agitation, aggression, depression.
Respiratory : Immediate bronchospasm, asthma exacerbation, dyspnea, wheeze, chest tightness, bronchospasm, cough.
Skin : Pruritus, contusions, ecchymoses.
Eosinophilic Conditions : In rare cases, patients on inhaled fluticasone propionate may present with systemic eosinophilic conditions, with some patients presenting with clinical features of vasculitis consistent with Churg-Strauss syndrome, a condition that is often treated with systemic corticosteroid therapy. These events usually, but not always, have been associated with the reduction and/or withdrawal of oral corticosteroid therapy following the introduction of fluticasone propionate. Cases of serious eosinophilic conditions have also been reported with other inhaled corticosteroids in this clinical setting. Physicians should be alert to eosinophilia, vasculitic rash, worsening pulmonary symptoms, cardiac complications, and/or neuropathy presenting in their patients. A causal relationship between fluticasone propionate and these underlying conditions has not been established (see PRECAUTIONS, Eosinophilic Conditions).
OVERDOSAGE :
Chronic overdosage may result in signs/symptoms of hypercorticism (see PRECAUTIONS). Inhalation by healthy volunteers of a single dose of 4000 mug of fluticasone propionate inhalation powder or single doses of 1760 or 3520 mug of fluticasone propionate inhalation aerosol was well tolerated. Fluticasone propionate given by inhalation aerosol at doses of 1320 mug twice daily for 7 to 15 days to healthy human volunteers was also well tolerated. Repeat oral doses up to 80 mg daily for 10 days in healthy volunteers and repeat oral doses up to 20 mg daily for 42 days in patients were well tolerated. Adverse reactions were of mild or moderate severity, and incidences were similar in active and placebo treatment groups. The oral and subcutaneous median lethal doses in mice and rats were >1000 mg/kg (>2000 and >4100 times, respectively, the maximum recommended daily inhalation dose in adults and >9600 and >19,000 times, respectively, the maximum recommended daily inhalation dose in children on a mg/m2 basis).
DOSAGE AND ADMINISTRATION :
Fluticasone propionate should be administered by the orally inhaled route in patients 4 years of age and older for inhalation powder and in patients 12 years of age and older for inhalation aerosol. Individual patients will experience a variable time to onset and degree of symptom relief. Generally, fluticasone propionate inhalation powder and aerosol have a relatively rapid onset of action for an inhaled corticosteroid. Improvement in asthma control following inhaled administration of fluticasone propionate can occur within 24 hours of beginning treatment, although maximum benefit may not be achieved for 1 to 2 weeks or longer after starting treatment.
After asthma stability has been achieved (see TABLE 3 and TABLE 4), it is always desirable to titrate to the lowest effective dose to reduce the possibility of side effects. Inhalation powder doses as low as 50 mug twice daily have been shown to be effective in some patients. For patients who do not respond adequately to the starting dose after 2 weeks of therapy, higher doses may provide additional asthma control. The safety and efficacy of fluticasone propionate when administered in excess of recommended doses have not been established.
Rinsing the mouth after inhalation is advised.
The recommended starting dose and the highest recommended dose of fluticasone propionate, based on prior anti-asthma therapy, are listed in TABLE 3 for inhalation powder and TABLE 4 for inhalation aerosol.
TABLE 3 Inhalation Powder Dosage
Previous Therapy
Recommended Starting Dose
Highest Recommended Dose
Bronchodilators alone
100 mug twice daily
Inhaled corticosteroids
100-250 mug twice daily*
Oral corticosteroids
1000 mug twice daily
Children 4 to 11 Years
50 mug twice daily
* Starting doses above 100 mug twice daily for adults and adolescents and 50 mug twice daily for children 4 to 11 years of age may be considered for patients with poorer asthma control or those who have previously required doses of inhaled corticosteroids that are in the higher range for that specific agent. NOTE: In all patients, it is desirable to titrate to the lowest effective dose once asthma stability is achieved.
For Patients Currently Receiving Chronic Oral Corticosteroid Therapy: Prednisone should be reduced no faster than 2.5 mg/day on a weekly basis, beginning after at least 1 week of therapy with fluticasone propionate inhalation powder. Patients should be carefully monitored for signs of asthma instability, including serial objective measures of airflow, and for signs of adrenal insufficiency (see WARNINGS). Once prednisone reduction is complete, the dosage of fluticasone propionate should be reduced to the lowest effective dosage.
This dosing recommendation is based on clinical data from a study conducted using fluticasone propionate inhalation aerosol. No clinical trials have been conducted in patients on oral corticosteroids using the inhalation powder formulation; no direct assessment of the clinical comparability of equal nominal doses for the inhalation powder and inhalation aerosol formulations in this population has been conducted.
TABLE 4 Inhalation Aerosol Dosage
88-220 mug twice daily*
* Starting doses above 88 mug twice daily may be considered for patients with poorer asthma control or those who have previously required doses of inhaled corticosteroids that are in the higher range for that specific agent. NOTE: In all patients, it is desirable to titrate to the lowest effective dose once asthma stability is achieved.
For Patients Currently Receiving Chronic Oral Corticosteroid Therapy : Prednisone should be reduced no faster than 2.5 mg/day on a weekly basis, beginning after at least 1 week of therapy with fluticasone propionate inhalation aerosol. Patients should be carefully monitored for signs of asthma instability, including serial objective measures of airflow, and for signs of adrenal insufficiency (see WARNINGS). Once prednisone reduction is complete, the dosage of fluticasone propionate should be reduced to the lowest effective dosage.
Geriatric Use : In studies where geriatric patients (65 years of age or older, see PRECAUTIONS) have been treated with fluticasone propionate inhalation powder or aerosol, efficacy and safety did not differ from that in younger patients. Consequently, no dosage adjustment is recommended.
Directions for Use : Illustrated Patient’s Instructions for Use accompany each package of Flovent Rotadisk and Flovent Inhalation Aerosol.
HOW SUPPLIED :
Flovent Rotadisk is available in 50 mug, 100 mug, and 250 mug strengths.
Storage : Store at controlled room temperature, 20-25°C (68-77°F) in a dry place. Keep out of reach of children. Do not puncture any fluticasone propionate Rotadisk blister until taking a dose using the Diskhaler.
Use the Rotadisk blisters within 2 months after opening of the moisture-protective foil overwrap or before the expiration date, whichever comes first. Place the sticker provided with the product on the tube and enter the 2-month use date on the sticker.
Flovent 44 mug : Each actuation of the inhaler delivers 44 mug of fluticasone propionate from the actuator.
Flovent 110 mug : Each actuation of the inhaler delivers 110 mug of fluticasone propionate from the actuator.
Flovent canisters are for use with Flovent inhalation aerosol actuators only. The actuators should not be used with other aerosol medications.
The correct amount of medication in each inhalation cannot be assured after 60 inhalations from the 7.9-g canister or 120 inhalations from the 13-g canister even though the canister is not completely empty. The canister should be discarded when the labeled number actuations has been used.
Storage : Store between 2-30°C (36-86°F). Store canister with nozzle end down. Protect from freezing temperatures and direct sunlight.
Avoid spraying in eyes. Contents under pressure. Do not puncture or incinerate. Do not store at temperatures above 120°F. Keep out of reach of children. For best results, the canister should be at room temperature before use. Shake well before using.
Note : The statement below is required by the Federal Government’s Clean Air Act for all products containing or manufactured with chlorofluorocarbons (CFCs).
Warning : Contains trichlorofluoromethane and dichlorodifluoromethane, substances which harm public health and environment by destroying ozone in the upper atmosphere.
A notice similar to the above warning has been placed in the patient information leaflet of this product pursuant to EPA regulations.
Fluticasone Propionate (Intranasal)
Fluticasone propionate is a synthetic corticosteroid with the chemical name of S-fluoromethyl 6alpha,9alpha-difluoro-11beta-hydroxy-16alpha-methyl-3-oxo-17alpha-propionyloxyandrosta -1, 4-diene-17beta-carbothioate.
Fluticasone propionate is a white to off-white powder with a molecular weight of 500.6. It is practically insoluble in water, freely soluble in dimethyl sulfoxide and dimethylformamide, and slightly soluble in methanol and 95% ethanol.
Fluticasone propionate nasal spray 50 mug is an aqueous suspension of microfine fluticasone propionate for topical administration to the nasal mucosa by means of a metering, atomizing spray pump. Flonase nasal spray also contains microcrystalline cellulose and carboxymethylcellulose sodium, dextrose, 0.02% w/w benzalkonium chloride, polysorbate 80, and 0.25% w/w phenylethyl alcohol, and has a pH between 5 and 7.
It is necessary to prime the pump before first use or after a period of non-use (1 week or more). After initial priming (6 actuations), each actuation delivers 50 mug of fluticasone propionate in 100 mg of formulation through the nasal adapter. Each bottle of Flonase nasal spray provides 120 metered sprays. After 120 metered sprays, the amount of fluticasone propionate delivered per actuation may not be consistent and the unit should be discarded.
Fluticasone propionate is a synthetic, trifluorinated corticosteroid with anti-inflammatory activity. In vitro dose response studies on a cloned human glucocorticoid receptor system involving binding and gene expression afforded 50% responses at 1.25 and 0.17 nM concentrations, respectively. Fluticasone propionate was threefold to fivefold more potent than dexamethasone in these assays. Data from the McKenzie vasoconstrictor assay in man also support its potent glucocorticoid activity.
In preclinical studies, fluticasone propionate revealed progesterone-like activity similar to the natural hormone. However, the clinical significance of these findings in relation to the low plasma levels (see Pharmacokinetics) is not known.
The precise mechanism through which fluticasone propionate affects allergic rhinitis symptoms is not known. Corticosteroids have been shown to have a wide range of effects on multiple cell types (e.g., mast cells, eosinophils, neutrophils, macrophages, and lymphocytes) and mediators (e.g., histamine, eicosanoids, leukotrienes, and cytokines) involved in inflammation. In seven trials in adults, fluticasone propionate nasal spray has decreased nasal mucosal eosinophils in 66% (35% for placebo) of patients and basophils in 39% (28% for placebo) of patients. The direct relationship of these findings to long-term symptom relief is not known.
Fluticasone propionate nasal spray, like other corticosteroids, is an agent that does not have an immediate effect on allergic symptoms. A decrease in nasal symptoms has been noted in some patients 12 hours after initial treatment with fluticasone propionate nasal spray. Maximum benefit may not be reached for several days. Similarly, when corticosteroids are discontinued, symptoms may not return for several days.
Absorption : The activity of fluticasone propionate nasal spray is due to the parent drug, fluticasone propionate. Indirect calculations indicate that fluticasone propionate delivered by the intranasal route has absolute bioavailability averaging less than 2%. After intranasal treatment of patients with allergic rhinitis for 3 weeks, fluticasone propionate plasma concentrations were above the level of detection (50 pg/ml) only when recommended doses were exceeded and then only in occasional samples at low plasma levels. Due to the low bioavailability by the intranasal route, the majority of the pharmacokinetic data was obtained via other routes of administration. Studies using oral dosing of radiolabeled drug have demonstrated that fluticasone propionate is highly extracted from plasma and absorption is low. Oral bioavailability is negligible, and the majority of the circulating radioactivity is due to an inactive metabolite.
Distribution : Following intravenous administration, the initial dispostion phase for fluticasone propionate was rapid and consistent with its high lipid solubility and tissue binding. The volume of distribution averaged 4.2 L/kg. The percentage of fluticasone propionate bound to human plasma proteins averaged 91% with no obvious concentration relationship. Fluticasone propionate is weakly and reversibly bound to erythrocytes and freely equilibrates between erythrocytes and plasma. Fluticasone propionate is not significantly bound to human transcortin.
Metabolism : The total blood clearance of fluticasone propionate is high (average, 1093 ml/min), with renal clearance accounting for less than 0.02% of the total. The only circulating metabolite detected in man is the 17beta-carboxylic acid derivative of fluticasone propionate, which is formed through the cytochrome P450 3A4 pathway. This inactive metabolite had approximately 2000 times less affinity than the parent drug for the clucocorticoid receptor of human lung cytosol in vitro and negligible pharmacological activity in animal studies. Other metabolites detected in vitro using cultured human hepatoma cells have not been detected in man.
In a multiple-dose drug interaction study, coadministration of orally inhaled fluticasone propionate (500 mug twice daily) and erythromycin (333 mg three times daily) did not affect fluticasone propionate pharmacokinetics.
In a drug interaction study, coadministration of orally inhaled fluticasone propionate (1000 mug, 5 times the maximum daily intranasal dose) and ketoconazole (200 mg once daily) resulted in increased fluticasone propionate concentrations, a reduction in plasma cortisol AUC, and no effect on urinary excretion of cortisol.
Excretion : Following intravenous dosing, fluticasone propionate showed polyexponential kinetics and had a terminal elimination half-life of approximately 7.8 hours. Less than 5% of a radiolabeled oral dose was excreted in the urine as metabolites, with the remainder excreted in the feces as parent drug and metabolites.
Fluticasone propionate was not studied in any special populations, and no gender-specific pharmacokinetic data have been obtained.
In a trial to evaluate the potential systemic and topical effects of fluticasone propionate nasal spray on allergic rhinitis symptoms, the benefits of comparable drug blood levels produced by fluticasone propionate nasal spray and oral fluticasone propionate were compared. The doses used were 200 mug of fluticasone propionate nasal spray, the nasal spray vehicle (plus oral placebo), and 5 and 10 mg of oral fluticasone propionate (plus nasal spray vehicle) per day for 14 days. Plasma levels were undetectable in the majority of patients after intranasal dosing, but present at low levels in the majority after oral dosing. Fluticasone propionate nasal spray was significantly more effective in reducing symptoms of allergic rhinitis than either the oral fluticasone propionate or the nasal vehicle. This trial demonstrated that the therapeutic effect of fluticasone propionate nasal spray can be attributed to the topical effects of fluticasone propionate.
In another trial, the potential systemic effects of fluticasone propionate nasal spray on the hypothalamic-pituitary-adrenal (HPA) axis were also studied in allergic patients. Fluticasone propionate nasal spray given as 200 mug once daily or 400 mug twice daily was compared with placebo or oral prednisone 7.5 or 15 mg given in the morning. Fluticasone propionate nasal spray at either dose for 4 weeks did not affect the adrenal response to 6-hour cosyntropin stimulation, while both doses of oral prednisone significantly reduced the response to cosyntropin.
Individualization of Dosage:
Adult patients may be started on 200-mug once-a-day regimen (two 50-mug sprays in each nostril once a day). An alternative 200-mug/day dosage regimen can be given as 100 mug twice daily (one 50-mug spray in each nostril twice a day).
Individual patients will experience a variable time to onset and different degree of symptom relief. In 4 randomized, double-blind, placebo-controlled, parallel group allergic rhinitis studies and 2 studies of patients in an outdoor “park” setting (park studies), a decrease in nasal symptoms in treated subjects compared to placebo was shown to occur as soon as 12 hours after treatment with a 200-mug dose of fluticasone propionate nasal spray. Maximum effect may take several days. Patients who have responded may be able to be maintained (after 4 to 7 days) on 100 mug per day (one spray in each nostril once daily).
Pediatric patients 4 years of age and older should be started with 100 mug (one spray in each nostril once-a-day). Treatment with 200 mug (two sprays in each nostril once daily or one spray in each nostril twice daily) should be reserved for pediatric patients not adequately responding to 100 mug daily. Once adequate control is achieved, the dosage may be decreased to 100 mug (one spray in each nostril) daily.
Maximum total daily doses should not exceed two sprays in each nostril (total dose, 200 mug per day). There is no evidence that exceeding the recommended dose is more effective.
A total of 13, randomized, double-blind, parallel, multicenter, vehicle-controlled clinical trials were conducted in the United States in adults and pediatric patients (4 years of age and older) with seasonal of perennial allergic rhinitis. The trials included 2633 adults (1439 men and 1194 women) with mean age of 37 years (range, 18 to 79). A total of 440 adolescents (405 boys and 35 girls), mean age of 14 (range, 12 to 17), and 500 children (325 boys and 175 girls), mean age of 9 (range, 4 to 11) were also studied. The overall racial distribution was 89% white, 4% black, and 7% other. These trials evaluated the total nasal symptoms scores (TNSS) that included rhinorrhea, nasal obstruction, sneezing, and nasal itching in known allergic patients who were treated for 2 to 24 weeks. Subjects treated with fluticasone propionate nasal spray exhibited significantly greater decreases in TNSS than vehicle placebo-treated patients. Nasal mucosal basophils and eosinophils were also reduced at the end of treatment in adult studies; however, the clinical significance of this decrease is not known.
There were no significant differences between fluticasone propionate regimens whether administered as a single daily dose of 200 mug (two 50-mug sprays in each nostril) or as 100 mug (one 50-mug spray in each nostril) twice daily in six clinical trials. A clear dose response could not be identified in clinical trials. In one trial, 200 mug/day was slightly more effective than 50 mug/day during the first few days of treatment, thereafter, no difference was seen.
Three randomized, double-blind, parallel, vehicle-controlled trials were conducted in 1191 patients with perennial nonallergic rhinitis. These trials evaluated the patient-rated total nasal symptom scores (nasal obstruction, postnasal drip, rhinorrhea) in patients treated for 28 days of double-blind therapy and in one of the three trials for 6 months of open-label treatment. Two of these trials demonstrated that patients treated with fluticasone propionate nasal spray at a dose of 100 mug twice daily exhibited statistically significant decreases in total nasal symptom scores compared with patients treated with vehicle.
Fluticasone propionate nasal spray is indicated for the management of the nasal symptoms of seasonal and perennial allergic and nonallergic rhinitis in adults and pediatric patients 4 years of age and older.
Safety and effectiveness of fluticasone propionate nasal spray in children below 4 years of age have not been adequately established.
Fluticasone propionate nasal spray is contraindicated in patients with a hypersensitivity to any of its ingredients.
The replacement of a systemic corticosteroid with a topical corticosteroid can be accompanied by signs of adrenal insufficiency, and in addition some patients may experience symptoms of withdrawal, e.g., joint and/or muscular pain, lassitude, and depression. Patients previously treated for prolonged periods with systemic corticosteroids and transferred to topical corticosteroids should be carefully monitored for acute adrenal insufficiency in response to stress. In those patients who have asthma or other clinical conditions requiring long-term systemic corticosteroid treatment, too rapid a decrease in systemic corticosteroids may cause a severe exacerbation of their symptoms.
The concomitant use of intranasal corticosteroids with other inhaled corticosteroids could increase the risk of signs or symptoms of hypercorticism and/or suppression of the HPA axis.
Patients who are on immunosuppressant drugs are more susceptible to infections than healthy individuals. Chickenpox and measles, for example, can have a more serious or even fatal course in patients on immunosuppressant doses of corticosteroids. In such patients who have not had these diseases, particular care should be taken to avoid exposure. How the dose, route, and duration of corticosteroid administration affects the risk of developing a disseminated infection is not known. The contribution of the underlying disease and/or prior corticosteroid treatment to the risk is also not known. If exposed to chickenpox, prophylaxis with varicella zoster immune globulin (VZIG) may be indicated. If exposed to measles, prophylaxis with pooled intramuscular immunoglobulin (IG) may be indicated. (See the respective prescribing informatio for complete VZIG and IG information.) If chickenpox develops, treatment with antiviral agents may be considered.
PRECAUTIONS :
General : Rarely, immediate hypersensitivity reactions or contact dermatitis may occur after the administration of fluticasone propionate nasal spray. Rare instances of wheezing, nasal septum perforation, cataracts, glaucoma and increased intraocular pressure have been reported following the intranasal application of corticosteroids, including fluticasone propionate.
Use of excessive doses of corticosteroids may lead to signs or symptoms of hypercorticism, suppression of HPA function, and/or reduction of growth velocity in children or teenagers. Physicians should closely follow the growth of children and adolescents taking corticosteroids, by any route, and weigh the benefits of corticosteroid therapy against the possibility of growth suppression if growth appears slowed.
Although systemic effects have been minimal with recommended doses of fluticasone propionate nasal spray, potential risk increases with larger doses. Therefore, larger than recommended doses of fluticasone propionate nasal spray should be avoided.
When used at higher than recommended doses, or in rare individuals at recommended doses, systemic corticosteroid effects such as hypercorticism and adrenal suppression may appear. If such changes occur, the dosage of fluticasone propionate nasal spray should be discontinued slowly consistent with accepted procedures for discontinuing oral corticosteroid therapy.
In clinical studies with fluticasone propionate administered intranasally, the development of localized infections of the nose and pharynx with Candida albicans has occurred only rarely. When such an infection develops, it may require treatment with appropriate local therapy and discontinuation of treatment with fluticasone propionate nasal spray. Patients using fluticasone propionate nasal spray over several months or longer should be examined periodically for evidence of Candida infection or other signs of adverse effects on the nasal mucosa.
Fluticasone propionate nasal spray should be used with caution, if at all, in patients with active or quiescent tuberculous infection; untreated local or systemic fungal or bacterial, or systemic viral infections or parasitic infection; or ocular herpes simplex.
Because of the inhibitory effect of corticosteroids on wound healing, patients who have experienced recent nasal septal ulcers, nasal surgery, or nasal trauma should not use a nasal corticosteroid until healing has occurred.
Information for the Patient : Patients being treated with fluticasone propionate nasal spray should receive the following information and instructions. This information is intended to aid them in the safe and effective use of this medication. It is not a disclosure of all possible adverse or intended effects.
Patients should be warned to avoid exposure to chickenpox or measles and, if exposed, to consult their physician without delay.
Patients should use fluticasone propionate nasal spray at regular intervals as directed since its effectiveness depends on its regular use. A decrease in nasal symptoms may occur as soon as 12 hours after starting therapy with fluticasone propionate nasal spray. Results in several clinical trials indicate statistically significant improvement within the first day or two of treatment; however, the full benefit of fluticasone propionate nasal spray may not be achieved until treatment has been administered for several days. The patient should not increase the prescribed dosage but should contact the physician if symptoms do not improve or if the condition worsens. For the proper use of the nasal spray and to attain maximum improvement, the patient should read and follow carefully the accompanying patient’s instructions.
Carcinogenesis, Mutagenesis, and Impairment of Fertility : Fluticasone propionate demonstrated no tumorigenic potential in mice at oral doses up to 1000 mug/kg (approximately 20 times the maximum recommended daily intranasal dose in adults and approximately 10 times the maximum recommended daily intranasal dose in children on a mug/m2 basis) for 78 weeks or in rats at inhalation doses up to 57 mug/kg (approximately 2 times the maximum recommended daily intranasal dose in adults and approximately equivalent to the maximum recommended daily intranasal dose in children on a mug/m2 basis) for 104 weeks.
No evidence of impairment of fertility was observed in reproductive studies conducted in male and female rats at subcutaneous doses up to 50 mug/kg (approximately 2 times the maximum recommended daily intranasal dose in adults on a mug/m2 basis). Prostate weight was significantly reduced at a subcutaneous dose of 50 mug/kg.
Pregnancy, Teratogenic Effects, Pregnancy Category C : Subcutaneous studies in the mouse and rat at 45 and 100 mug/kg, respectively (approximately equivalent to and 4 times the maximum recommended daily intranasal dose in adults on a mug/m2 basis, respectively) revealed fetal toxicity characteristic of potent corticosteroid compounds, including embryonic growth retardation, omphalocele cleft palate, and retarded cranial ossification.
In the rabbit, fetal weight reduction and cleft palate were observed at a subcutaneous dose of 4 mug/kg (less than the maximum recommended daily intranasal dose in adults on a mug/m2 basis).
However, no teratogenic effects were reported at oral doses up to 300 mug/kg (approximately 25 times the maximum recommended daily intranasal dose in adults on a mug/m2 basis) of fluticasone propionate to the rabbit. No fluticasone propionate was detected in the plasma in this study, consistent with the established low bioavailability following oral administration (see CLINICAL PHARMACOLOGY).
Fluticasone propionate crossesd the placenta following oral administration of 100 mug/kg to rats or 300 mug/kg to rabbits (approximately 4 and 25 times, respectively, the maximum recommended daily intranasal dose in adults on a mug/m2 basis).
Nursing Mothers : It is not known whether fluticasone propionate is excreted in human breast milk. When tritiated fluticasone propionate was administered to rats at a subcutaneous dose of 10 mug/kg (less than the maximum recommended daily intranasal dose in adults on a mug/m2 basis), radioactivity was excreted in the milk. Because other corticosteroids are excreted in human milk, caution should be exercised when fluticasone propionate nasal spray is administered to a nursing woman.
Pediatric Use : Five hundred (500) patients aged 4 to 11 years of age and 440 patients aged 12 to 17 years were studied in U.S. clinical trials with fluticasone propionate nasal spray. The safety and effectiveness of fluticasone propionate nasal spray in children below 4 years of age have not been established.
Oral and, to a less clear extent, inhaled and intranasal corticosteroids have been shown to have the potential to cause a reduction in growth velocity in children and adolescents with extended use. If a child or adolescent on any corticosteroid appears to have growth suppression, the possibility that they are particularly sensitive to this effect of corticosteroids should be considered (see PRECAUTIONS).
Geriatric Use : A limited number of patients above 60 years of age (n = 275) have been treated with fluticasone propionate nasal spray in U.S. and non-U.S. clinical trials. While the number of patients is too small to permit separate analysis of efficacy and safety, the adverse reactions reported in this population were similar to those reported by younger patients.
In a placebo-controlled, crossover study in eight healthy volunteers, coadministration of a single dose of orally inhaled fluticasone propionate (1000 mug, 5 times the maximum daily intranasal dose) with multiple doses of ketoconazole (200 mg) to steady state resulted in increased mean fluticasone propionate concentrations, a reduction in plasma cortisol AUC, and no effect on urinary excretion of cortisol. This interaction may be due to an inhibition of the cytochrome P450 3A4 isoenzyme system by ketoconazole, which is also the route of metabolism of fluticasone propionate. No drug interaction studies have been conducted with fluticasone propionate nasal spray; however, care should be exercised when fluticasone propionate is coadministered with long-term ketoconazole and other known cytochrome P450 3A4 inhibitors.
In controlled U.S. studies, more than 3300 patients with seasonal allergic, perennial allergic, or perennial nonallergic rhinitis received treatment with intranasal fluticasone propionate. In general, adverse reactions in clinical studies have been primarily associated with irritation of the nasal mucous membranes, and the adverse reactions were reported with approximately the same frequency by patients treated with the vehicle itself. The complaints did not usually interfere with treatment. Less than 2% of patients in clinical trials discontinued because of adverse events; this rate was similar for vehicle placebo and active comparators.
Systemic corticosteroid side effects were not reported during controlled clinical studies up to 6 months’ duration with fluticasone propionate nasal spray. If recommended doses are exceeded, however, or if individuals are particularly sensitive, or taking fluticasone propionate nasal spray in conjunction with administration of other corticosteroids, symptoms of hypercorticism e.g., Cushing’s syndrome, could occur.
The following incidence of common adverse reactions (>3%, where incidence in fluticasone propionate-treated subjects exceeded placebo) is based upon seven controlled clinical trials in which 536 patients (57 girls and 108 boys aged 4 to 11 years, 137 female and 234 male adolescents and adults) were treated with fluticasone propionate nasal spray 200 mug once daily over 2 to 4 weeks and two controlled clinical trials in which 246 patients (119 female and 127 male adolescents and adults) were treated with fluticasone propionate nasal spray 200 mug once daily over 6 months (see TABLE 1). Also included in the table are adverse events from two studies in which 167 children (45 girls and 122 boys aged 4 to 11 years) were treated with fluticasone propionate nasal spray 100 mug once daily for 2 to 4 weeks.
TABLE 1 Overall Adverse Experiences with >3% Incidence on Fluticasone Propionate in Controlled Clinical Trials with Fluticasone Propionate Nasal Spray in Patients 4 Years with Seasonal or Perennial Allergic Rhinitis
Fluticasone Propionate Nasal Spray Once Daily
Vehicle Placebo
(n=758) %
Nasal burning/nasal irritation
Nausea/vomiting
Other adverse events that occurred in 3% but 1% of patients and that were more common with fluticasone propionate (with uncertain relationship to treatment) included: Blood in nasal mucus, runny nose, abdominal pain, diarrhea, fever, flu-like symptoms, aches and pains, dizziness, bronchitis.
Observed During Clinical Practice : In addition to adverse events reported from clinical trials, the following events have been identified during postapproval use of fluticasone propionate in clinical practice. Because they are reported voluntarily from a population of unknown size, estimates of frequency cannot be made. These events have been chosen for inclusion due to either their seriousness, frequency of reporting, causal connection to fluticasone propionate, occurrence during clinical trials, or a combination of these factors.
General : Hypersensitivity reactions, including angioedema, skin rash, edema of the face and tongue, pruritus, urticaria, bronchospasm, wheezing, dyspnea, and anaphylaxis/anaphylactoid reactions, which in rare instances were severe.
Ear, Nose, and Throat : Alteration or loss of sense of taste and/or smell and, rarely, nasal septal perforation, nasal ulcer, sore throat, throat irritation and dryness, cough, hoarseness, and voice changes.
Eye : Dryness and irritation, conjunctivitis, blurred vision, glaucoma, increased intraocular pressure, and cataracts.
Chronic overdosage with fluticasone propionate nasal spray may result in signs/symptoms of hypercorticism (see PRECAUTIONS). Intranasal administration of 2 mg (10 times the recommended dose) of fluticasone propionate twice daily for 7 days to healthy human volunteers was well tolerated. Single oral doses up to 16 mg have been studied in human volunteers with no acute toxic effects reported. Repeat oral doses up to 80 mg daily for 10 days in volunteers and repeat oral doses up to 10 mg daily for 14 days in patients were well tolerated. Adverse reactions were of mild or moderate severity, and incidences were similar in active and placebo treatment groups. Acute overdosage with this dosage form is unlikely since one bottle of fluticasone propionate nasal spray contains approximately 8 mg of fluticasone propionate.
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Magnificent Graduations with an International Footprint for the graduates of NYC Group in Athens-Thessaloniki, Prague, Tirana.
New York College Commencement 2017
The New York College Graduation ceremony was characterized by a strong sense of hope and optimism for the future and was in turn indicative of the certainty that the new graduates have what they need in order to succeed in tomorrow’s endeavors. Namely, the Bachelor, Master, and PhD, degrees acquired through studies exclusively in Greece constitute their passport to professional success and development.
The 2017 New York College Graduation ceremony took place on 5 July beside the ancient Temple dedicated to Zeus and with the Acropolis in the background. Attending were graduates, their parents, prominent politicians and academics.
The Earl of St. Andrews, Chancellor of the University of Bolton
The Earl of St. Andrews and Chancellor of the University of Bolton gave his speech exclusively in Greek in honor of his Hellenic heritage. The Earl mentioned “Isocrates who said that just as we see the bee settling on all the flowers, and sipping the best from each, so also those who aspire to culture ought not to leave anything untasted, but should gather useful knowledge from every source. The University of Bolton and New York College have achieved much always keeping in mind what is best for our students.”
Stavros Lekkakos, President of MIG, received the honorary Doctorate of Arts of the University of Bolton from the Earl of St. Andrews.
In his speech, the President and Founder of the New York College Educational Group, Elias Foutsis, stated that” Being graduates of NYC and its affiliated universities, you are well equipped with knowledge, skills and experience, moral and social principles. It is this combination of skills and knowledge which will allow you to rise above difficulties or dilemmas in your work environment and ultimately make you winners.”
Stamatina Zourmpouli made an impact with her Valedictorian speech in which she stated “With my speech I wish to reassure you dear parents, that your decision to bring us to this college was the right one. You made the best choice by choosing the best to provide and equip us with the necessary tools to go out and fight for what we deserve. You chose the best to educate us and influence our personality, values and perceptions. You chose the best to help us build solid foundations to rely on, to move on with success in our life, both personal and professional.”
Among the evening’s distinguished guests were: Dr. Merodie Hancock, President, State University of New York, Empire State College and Dr. Sheila Aird, Director of European Academic Programs; Dr. Alec Coutroubis, from the University of Greenwich and from the Université Toulouse 1 Capitole, Professor Herve Penan and Mme Isabelle Solé. Moroever, Mr. Vasilios Kokkalis, Deputy Minister of Rural Development and Foods and Professor Theodore Fortsakis, Member of the Hellenic Parliament for State, former Rector, University of Athens, attended the event.
ΤNew York College has been offering multicultural quality education since 1989 in partnership with well-known Universities in the USA and Europe, such as State University of New York, Empire State College, the University of Bolton, the University of Greenwich, Université Toulouse 1 Capitole, and the Varna Naval Academy Nikola Vaptsarov. New York College is the only private Greek educational institution to have established colleges and higher education institutions, in four cities: Athens, Thessaloniki, Prague and Tirana.
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This Women-Led Film Refocuses Charles Manson's Murders
Jeena Sharma
They say the '60s ended on August 1969. To this day, Charles Manson remains one of the most notorious killers in American history. Those old enough to remember recall the mass murders of actress Sharon Tate, her unborn child and four other guests who were visiting, as one of the most jarring and traumatic incidents of the time.
Somewhere in the midst of the Vietnam war and a collective cultural awakening of sorts — fueled by fierce activism, and hippies alike — was a man who shook up the entire nation all on his own.
It's why even after his death, Manson continues to induce equal amounts of horror and fascination, best evidenced through the innumerable books, essays, and films centered on the harrowing subject.
In the past year itself, several notable features such as The Haunting of Sharon Tate and Quentin Tarantino's soon-to-be released Once Upon a Time in Hollywood have tried to dissect the mysterious working of the Manson clan, as well the man who orchestrated such a horror.
Yet, Mary Harron and Guinevere Turner (also the team behind American Psycho) hold no such fascination of Manson, as shown through their recently debuted independent film, Charlie Says.
"I think we know why he did it," Harron told me in an interview earlier last year. "He's not that enigmatic; he's a very deformed human being. He had a terrible life, and it warped him. It's hard to say if he was a sociopath or a psychopath but he was definitely not sane. There was a lot of hate and anger and he was a deeply disturbed person who also wanted to keep his hold on his followers."
Harron's interest lied in unearthing the trauma of his legion of followers, more precisely the three women who executed Manson's heinously planned murders. Susan Atkins, Patricia Krenwinkel and Leslie Van Houten, all of whom were imprisoned for life, occupy the prime focus in Charlie Says.
"We're trying to be respectful in finding humanity and understanding that they're not monsters. They were just really young girls that made awful choices."
Although Atkins passed away from cancer in 2009, Krenwinkel and Van Houten continue to carry out their sentences in complete obscurity with little hope for parole. Karlene Faith's The Long Prison Journey of Leslie van Houten and Atkin's Child of Satan, Child of God, along with extensive media coverage from the time form the main point of reference for the film.
"We were working more closely with Karlene Faith and her family," explains Marianne Rendón, who plays Atkins. "It was very important to understand that when a person is up for parole, any evidence — fictional or otherwise — can convince the jury to not grant them parole. These are real peoples' lives and it's an enormous responsibility. It's a really delicate line we're treading. It's not that we're excusing their behavior because it's terrible crimes they committed but we're also trying to be respectful in finding humanity and understanding that they're not monsters. They were just really young girls that made awful choices."
The film opens to the sunny outskirts of Southern California, where Manson's character (played by Matt Smith) offers an open-to-all utopia of sorts, free from the constraints of repressive societal rules. It's not too wild to imagine why that posed any fascination for young women fleeing from difficult childhoods and strained familial relationships.
Yet, it's hard to garner sympathy for the women who willingly and knowingly took away innocent lives in blind devotion to a man who called himself the second coming of Jesus and propelled prophecies of race wars. It's even harder to understand how one man could wield so much influence over seemingly grown women.
"I think [Patricia] grew up at a time when the most important thing in the world was to be chosen by a man," says Sosie Bacon, who plays Patricia Krenwinkel. "That's what women are taught to believe. She didn't feel she was beautiful, she had an overgrowth of hair on her body, and didn't get much attention from men. Then she met Charlie and he loved her. He told her she was beautiful and that she was the most important thing in his life. That is powerful. Patriarchy teaches us that from day one. So I understand why she followed him blindly and took his abuse and brainwashing for so long."
People forget the near constant sexual assault and abuse that became part of their lives during the year spent living on the farm as they were groomed to carry out Manson's plans. Not only did he himself physically and sexually assault the women, but he also routinely invited friends and strangers to exploit them.
"In the end, Manson was like a pimp, pimping them out as a commodity to his friends," Rendon says. "These women wouldn't even bat an eye because they just wanted to please Charlie."
Despite how quickly Manson distanced himself from the three women after their imprisonment, they remained devoted to him and his word. It was Faith's (who also co-wrote the script) near constant visits while they were in prison that ultimately broke the facade — another arc that Harron and Turner focus on throughout the story.
"I hate that it happened, but I understand it," Bacon adds. "Patricia had to face what she had done in prison and it was the most awful thing. She talks about it in a New York Times documentary. Watching her talk about denouncing Manson and accepting what she had done, it's really hard to not have empathy. Our movie forces us all to consider, 'What if?' What if it had been me in that context with that background, could I have done it? And that's a really uncomfortable thought to have, but it's important."
Rendon who also worked closely with Faith in fleshing out her on-screen character, believes "compartmentalizing" was one of the many ways the women coped with the reality of what they'd done once they were confronted with it. "I believe this is why [Atkins] became a born again Christian because she didn't know how else to process it and you see the transition to that in the film," she says.
It's a tricky line to walk both for an actor or a filmmaker, to empathize with characters so collectively despised. It's also why that intricate understanding of the women remains absent in the mainstream and from our own minds.
"I was surprised that Susan was so honest about her need for love, and connection and family from a very young age," says Rendon. "She described herself as desperate for attention; I think it's a very hard thing to admit. She wanted to appear tough, dangerous and interesting, which is why she ratted on to her cell mates."
"Loss, abandonment, and insecurity are more painful to play than blind devotion. It was also challenging to delve so deeply into a time period that I find to be so fraught with trauma, especially for women."
Although Atkins and Van Houten eventually came to terms with their actions, for the longest time Krenwinkel remained devoted to Manson's prescribed values. Regardless of the overwhelming evidence and persistence from her own friends, Bacon says her adamant dedication was reflective of how she dealt with trauma.
"I think my most challenging moments happened in the prison as Patrica's best friend 'Lulu' [Van Houten] began to denounce Manson and pull away from the ideals of 'the family,'" explains Bacon. "It feels strange to say that because it's all incredibly dark, but emotionally, that's when the world really started to crumble for Patricia. Before that, she was brainwashed to really believe she was doing the right thing, so true devotion to Charlie was her main objective. Obviously that isn't a simple feeling, but it is a less painful feeling. Loss, abandonment, and insecurity are more painful to play than blind devotion. It was also challenging to delve so deeply into a time period that I find to be so fraught with trauma, especially for women."
At a time where the Haunting of Sharon Tate got labeled exploitative and Tarantino is already attracting criticism for reportedly allotting very few lines to Margot Robbie's character, here's a film that dedicates almost all of its nearly two hour run time to the women.
But is a woman's trauma, let alone three, just as relevant and fascinating as a deranged man's vengeful and murderous fantasies?
Charlie Says is out in cinemas now and available on demand on Amazon Prime.
Photo courtesy of IFC Films
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The King is dead, but did Elvis ever rule Orlando? | Ask Orlando
By David Whitley
In summer 1956, Elvis Presley played Orlando for his 3rd time in the 1950s, and the newspaper's 'On the Town' columnist Jean Yothers got a kiss for the cameras. (ORLANDO SENTINEL FILE)
There was an ad in the newspaper May 11, 1955. The Hank Snow All-Star Jamboree was performing at Orlando’s municipal auditorium.
Under Snow’s photo was the list of warmup acts. Faron Young, The Wilburn Brothers, Mother Maybelle & The Carter Sisters, Slim Whitman, Elvis Presley….
Hey, whatever happened to that guy?
That sort of brings us to this week’s Ask Orlando question.
“Did Elvis ever come to Orlando and did he get in trouble for shaking his pelvis?”
Now’s a good time to answer since we are coming off Elvis Week, aka High Holy Days in Memphis. There were concerts, symposiums, Graceland tours, a 5K run (insert Fat Elvis joke), trips to his birthplace and a candlelight vigil.
It all revolved around the anniversary of Elvis’s death on Aug. 16, 1977. He was 42.
The King has now been dead as long as he was alive. Though you might be surprised at how well he’s living on.
According to Spotify, more than 16.5 million hours of Elvis music has been downloaded this year. The surprising thing is 18-22 year-olds stream his music almost as much as 45-59 year-olds.
Elvis Presley’s performance at Orlando’s Municipal Auditorium in August 1956 came just a month before his famed first appearance on ‘The Ed Sullivan Show.’ (Joy Wallace Dickinson / Orlando Sentinel)
I figured most millennials would laugh those who worship the King. They would think of that bloated druggie in the white jumpsuit who briefly would have been Michael Jackson’s father-in-law, not the preternatural force that changed the entertainment world.
As John Lennon said, “Nothing affected me until I heard Elvis. Without Elvis, there would be no Beatles.”
Maybe he sneaked over from Liverpool and caught that first show in Orlando. Elvis was just a few months removed from driving a truck for a living. Sentinel columnist Jean Yothers had never been to a “hillbilly music” show, much less heard of the guy in an orange jacket who came on before Slim Whitman.
“What really stole the show was this 20-year-old sensation, Elvis Presley,” Yothers wrote, “a real sex-box as far the teenage girls are concerned.”
Elvis returned to Orlando two months later as part of the Andy Griffith Show. Like the Hank Snow Jamboree, it was two shows in one night. This time, Yothers got an autograph from Elvis that read “Love Ya.”
Girls scream for Elvis Presley during a performance in Orlando on Aug. 8, 1956. (Orlando Sentinel)
She gave him some advice in the paper.
“He’s wearing himself out giving customers more than their money’s worth. I wanted to say to him, ‘Slow down, boy… your fame won’t disappear.'”
A few months later, Sun Records sold Elvis’s contract to RCA for $40,000, and Col. Tom Parker became his manager.
Elvis’s days of warming up for Mother Maybelle were over when Parker set up a Florida blitz in August of 1956.
Nine days, seven cities, 25 shows. All sold out.
By then, Elvis’s dangerously gyrating hips were preceding him. The prudes in Jacksonville wanted them banned.
Rev. Robert Gray of Trinity Baptist Church said Elvis had “achieved a new low in spiritual degeneracy.” Judge Marion Gooding threatened to have Elvis arrested for “impairing the morals of minors” if he broke into his “suggestive” movements.
Elvis and his pelvis somehow made it through six shows without getting busted. There were no such threats for his two shows in Orlando, much to the joy of female minors.
Elvis Presley performs in Orlando on Aug. 8, 1956, wowing his fans. (Orlando Sentinel)
The critics still weren’t impressed. A Sentinel story had this prediction: “He’s a fad, a fellow girls turn to for one of those mad, impetuous infatuations, whereas Perry Como and Eddie Fisher will still be around, the dependable types, when Presley is back driving his truck in Memphis.”
Well, not quite. Twenty-one years, a few hundred million records and too many fried-peanut-butter-and-banana sandwiches later, Elvis returned to Orlando in his private jet.
He played the Sports Stadium on Feb. 17, 1977. The barn-like structure near Bithlo held 7,200 people and was packed.
At 10:10 p.m., the stage went dark and “2001: A Space Odyssey” cranked up. The Elvis appeared in full Elvis glory: white jumpsuit, gold chains and diamond rings.
“He appears healthy, but somewhat overweight,” the Sentinel reported the next day.
The audience didn’t seem to notice.
“I think he drrriiiips sex appeal,” one woman said.
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“I hope his pants split,” a 25-year-old teacher said.
There was enough “suggestive” gyrating to make Elvis drip with sweat. He wiped his face with silk scarves and tossed them into the shrieking audience. After 21 songs, he finished with “Can’t Help Falling in Love.”
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Then the lights came up. Elvis had left the building. Six months later, he left the Earth.
So to answer the original question, Elvis played seven shows in Orlando. Unlike Jacksonville, our morals weren’t impaired by his pelvis.
And he never took Yothers’ advice to slow down, boy.
“Ask Orlando” is a weekly feature intended to solve local mysteries and enlighten readers. If you have a question about anything Orlando, send an email to dwhitley@orlandosentinel.com.
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I integrated Gainesville High School in 1965: The scars endure
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HPTLC Fingerprint Analysis of Plant Staminal Cells Products | OMICS International
Journal of Chromatography & Separation Techniques
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Research Article Open Access
HPTLC Fingerprint Analysis of Plant Staminal Cells Products
Marcello Nicoletti* and Chiara Toniolo
Department of Environmental Biology, Quality Control Center, University Sapienza of Rome, P.le A. Moro 500185, Rome, Italy
*Corresponding Author:
Marcello Nicoletti
Department of Environmental Biology
Quality Control Center
University Sapienza of Rome
P.le A. Moro 500185, Rome, Italy
Received date: September 20, 2012; Accepted date: October 26, 2012; Published date: October 29, 2012
Citation: Nicoletti M, Toniolo C (2012) HPTLC Fingerprint Analysis of Plant Staminal Cells Products. J Chromat Separation Techniq 3:148. doi:10.4172/2157-7064.1000148
Copyright: © 2012 Nicoletti M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Visit for more related articles at Journal of Chromatography & Separation Techniques
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Utilization of natural products is radically changing. Changes were mainly due to the outcome in the market of a plethora of new food supplements, and in particular those generally named botanicals for their common plant origin. The validation of these novel products needs powerful analytical devices tailored for the study of herbal extracts in order to assess composition and face their natural complexity as a resource. The last item is important and crucial for the capacity and utility of the analytical results that means that each product should be analyzed with the right approach. Having in mind these arguments, we selected HPTLC as useful tool for the analysis of products based on plant staminal (stem) cells. Nowadays these products, generally named bud-derivatives, are waiting scientific validation to obtain their own place into food supplements regulation, after gained that in the market. Our analyses, based on HPTLC fingerprints, were able to show bud-derivatives complex compositions that resulted very similar, but also in part different, to those of the corresponding leaf hydro-alcoholic extract.
HPTLC; Food supplements; Botanicals; Bud-therapy
Actually, much expectation concerns human stem cell and their possible applications in many fields, first the medical one. It is clear that a long way still must be done, considering also the ethical implications. Nowadays, researcher’s attention is focused on two main arguments: understand the principles of staminal cells derivation in embryonic stem (ES) and in induced pluripotent stem (iPS). Waiting that answers overcome questions and doubles, some easier applications started in the plant field. Utilizations were focused on meristematic tissues that can be considered as staminal cells in plants. Meristems are constituted by totipotent cells mainly present in apical parts, although also the parenchymal cells are able to work similarly if necessary. Their function consists in the generation of new cells that will differentiate according to their position and functionality. Meristems are divided into primary, mainly derived from the embryo and responsible of the tissue architecture of herbs, and secondary, from which derive the production of plant secondary structure, when present, including most of wood and of additional functional parts. The main difference with animal and human staminal cells is that meristems are active during all steps of plant life and scattered in several parts of the plant body [1-3].
New food supplements account for a multimillion market, and in particular those generally named botanicals for their common plant origin [4-6]. They are well accepted by consumers and based on the contaminated target between medical and dietary/nutritional expectations. Waiting for the results of the claims debate [7,8], attention can be focused on security, in particular on the assessment of the herbal composition, also in consideration of the important cases of adulteration by synthetic drugs to enhance activity [9-12].
The validation of these novel products need powerful analytical devices tailored for the study of herbal extracts in order to face their natural complexity in composition as a resource. Among botanicals, a special attention must be deserved to the most innovative products, like those utilized in bud-therapy. Bud-therapy possesses a special appeal. Probably, everything starts from spring revival or the miracle of a new life born from plant vitality, experimented by everyone in the simple act of planting a little piece of woody branch into the ground, just waiting for the spring of a splendid rose or a monumental ginkgo. The expectation is that the same vitality could be in some way captured and technologically transferred.
The therapeutic use of buds or other young and developing vegetal parts cannot be considered a new entry. Several animals when sick use to look for buds for recovering. In Ayurvedic and Chinese Traditional Medicine they have an important place in the therapeutic tools. Also in the Materia Medica, we can find several important references, from the use of poplar buds by Galeno and Nicolas De Hyrepse, up to Paracelso. The general idea was to profit of the renewing force of growing or new born parts of the plant. This concern was on the basis of the modern medical approaches, that started in ’50 by the medical doctor and botanist Pal Henry [13] and nowadays reported in the new uses approach based on botanicals and named in several ways, i.e. bud-, meristematic-, embrio-, phytoembrio-, blasto-therapy among others. For simplicity, we will adopt the term of bud-therapy, referring to a modern non-conventional medical therapy using plant raw materials rich in meristemic cells to obtain bud-derivatives products. Although increasing in public concern and request, bud-therapy is still in search of its proper definition, recognition, validation and normative acceptance.
The true epistemic tissue is very narrow, generally monolayer, and therefore very difficult to be separated from neighbouring cells, also by expert researchers in plant histology. Into a bud there is a mix of cells at different stages of differentiation, including the slide producing other cells. In bud-therapy, for production of bud-derivatives the raw material is restricted to fresh plant tissues or juvenile parts: buds, shoots, young roots and branches and their bark, as well as any other tissues considered in some way containing meristemic or developing cells. In some cases for the embryo presence also seeds and fruits are included.
Extracts are generally obtained by the use of a mix of ethanol/glycerine, followed by a possible dilution in accordance with the homeopathic method, as reported in the French Pharmacopoeia [13], where they were introduced from 1965. Two main products are therefore obtained: the GM (Glyceric Macerate) and it’s 10 times dilution, according the homeopathic method using a mixture of water/ethanol/glycerine 20:30:50 in order to obtain the solution 1 DH. In consideration of these characteristics and of the dilution method, they are associated to the homeopathy. These products have so far a restricted market, being present mainly in France, Italy and Germany, but their importance is in progress, including in the cosmetic field. The basic idea is that, for their special nature, they should help tissues to remain young and flexible.
About their chemical composition, the general consideration was that they mainly should contain hormones, some proteins, minerals, vitamins and water, whereas production of specific and secondary metabolites should be delayed to the differentiation step. The absence of active constituents was the main argument declared by denigrators of bud-derivatives, to evidence their uselessness and claim their return from the market.
Chemicals, reagents, materials and solutions
Methanol for analysis and other HPLC grade solvents were purchased from Sigma-Aldrich (Milan, Italy) and Carlo Erba (Milan, Italy) Samples. Detailed information, i.e. producers, production conditions, storage method, etc. can be obtained by directly asking the authors. Extracts utilised as mono-herbal standards were hydro alcoholic 95° extracts obtained from the market or by lab extraction of identified herbal raw materials (5 mg/10 mL), the last also used as reference to confirm the identities of the marketed ones.
Chromatographic equipment
The HPTLC system (CAMAG, Muttenz, Switzerland) consisted of (i) Linomat 5 sample applicator using 100 μL syringes and connected to a nitrogen tank; (ii) chamber ADC 2 containing twin trough chamber 20×10 cm; (iii) Camag TLC visualizer; (iv) Camag TLC scanner 3 linked to winCATS software
Sample preparation and application
The dried extracts of the analysed samples were weighted and dissolved in methanol (6 mg/mL).
Normal phase glass plates 20×10 cm (Merck, Darmstadt, Germany) with glass-backed layers silica gel 60 (2 μm thickness). Before use, plates were prewashed with methanol and dried for 3 min at 100°C. Filtered solutions were applied with nitrogen flow. The operating conditions were: syringe delivery speed, 10 s μL-1 (100 nL s-1); injection volume, 3 μL; band width, 8 mm; distance from bottom, 15 mm.
The HPTLC plates were developed in the automatic and reproducibly developing chamber ADC 2, saturated with the same mobile phase dichloromethane:methanol 9:1 (v/v) for 20 min at room temperature. The developing solvents (i.e. type of solvents and ratios) were carefully optimized before the analyses. The length of the chromatogram run was 70 mm from the point of application.
Derivatization reagents and inspection
The developed layers were allowed to dry on Camag TLC Plate eater III for 5 min and then derivatised with anhisaldehyde (1.5 ml p-anisaldehyde, 2.5 ml H2SO4, 1 ml AcOH in 37 ml EtOH) and then treated on Camag TLC Plate eater III for 5 min at 110°C. All treated plates were then inspected under a UV light at 254 or 366 nm or under white light upper and lower (WRT), respectively, at a Camag TLC visualizer, before and after derivatization.
Sample solution of the extracts were prepared and stored at room temperature for 3 days and then applied on the same HPTLC plated and the chromatogram evaluated for additional band. Similarly band stability was checked by keeping the resolved peaks and inspecting at intervals of 12, 24 and 49 h.
Overlapping of bands is a typical analytical challenge for complex mixtures like multi-ingredient products. HPTLC allowed a good separation and visualization of the constituents. Sample solutions of the extracts were found to be stable at 4°C for at least 1 month and for at least 3 days on the HPTLC plates. Repeatability was determined by running a minimum of three analyses. RF values for main selected compounds varied less than 0.02%. The effects of small changes in the mobile phase composition, mobile phase volume, and duration of saturation were minute and reduced by the direct comparison; On the contrary, the results were critically dependent on prewashing of HPTLC plates with methanol.
Towards validation
The misunderstanding coming from the relationship with homeopathic products and the meristemic nature of the raw material, leads to the common idea that these products should contain irrelevant constituents, at least some primary metabolites, few enzymes and proteins. In any case, the possibilities to demonstrate the contrary have to face the very low quantities of the secondary constituents and therefore the detection limit of the method must be very efficient. Furthermore, the analyses are complicated by the relevant presence of glycerine, covering and affecting most of the chromatograms. Another controversy concerns the real pharmacological properties of these products, generally considered like a placebo. However, if the activity is quite difficult to ascertain, the determination of the composition is another matter.
HPTLC, High Performance Thin Layer Chromatography, is the most recent evolution of planar chromatography and has been specifically tailored for analysis of natural products [14,15]. Typical product of the HPTLC is the fingerprint, as the individual chromatographic track representing, as near as possible, a mixture of organic substances [16,17]. Furthermore, the same plate can be visualized in several ways and individual spot quantitatively determined by densitometry. HPTLC already is adopted in modern validation of herbal drugs [18]. HPTLC fingerprints of main Chinese plant drugs extracts are reported in a special book of the Chinese Pharmacopoieas [19] and HPTLC analyses reported in US Herbal Pharmacopoeia [20]. Furthermore, the HPTLC and HPLC-DAD fingerprints have been officially recognized by World Health Organisation as methods to identify a species or its preparations by a characteristic chromatographic profile when it is not possible to identify an active principle [21].
HPTLC fingerprints of bud derivatives
The HPTLC fingerprint approach was applied to bus derivatives in order to reach two main goals: evidence the presence of constituents and test its possible role in the identification of the utilized raw material.
The first consideration concerns the high quantity of glycerine present in the products. As evidenced in Figure 1, glycerine can interfere highly in the chromatography, depriving the analysis of any quality and possible interpretation. On the other hand, a remove of the glycerine, partially or totally by solvent, could affect the real composition of the analyzed material. We were able to limit the interference of glycerine that was practically confined near the starting line with limited or null influence on the chromatogram, although in several cases the linearity of the spots is affected [22].
Figure 1: HPTLC analysis of bud-derivatives without any pre-treatment, evidencing the devastating effects of glycerine.
The HPTLC analyses evidenced the chemical contents of bud-derivatives (MG): the tracks contain spots of several secondary metabolites, in accordance with a specific fingerprint. This result was confirmed for rosemary products by the comparison of MG with the corresponding fingerprints of the hydro-alcoholic extracts (EI) of the leaves of same species (Figure 2). Also the densitometric conversion showed the same situation (Figure 3). The comparison with other mother tinctures (Figure 4) showed a relevant correspondence, allowing a botanical identification, but additional spots were generally present, confirming the peculiarity of staminal cells, as well as the peculiar extracting method, and therefore testifying for their specific use [23].
Figure 2: HPTLC analysis of bud-derivatives of rosemary. Visualization: WRT. Rosmarinus officinalis Tracks: 1 MG of young buds, 2 hydroalcholic extract of buds, 3 hydroalcholic extract of fresh leaves; 4 MG of mature buds.
Figure 3: Densitometric profiles of tracks of Figure 2.
Figure 4: HPTLC analysis of bud-derivatives. Visualization: UV 366 nm. Tracks: 1 Ribes nigrum MG, 2 Ficus carica MG, 3 Tilia tomentosa MG, 4 Rosmarinus officinalis MG, 5 Ribes nigrum EI, 6 Ficus carica EI, 7 Tilia tomentosa EI, 8 Rosmarinus officinalis EI.
The products obtained in accordance with the French Pharmacopoeia responded better to the separation, whereas products obtained using more polar solvents presented several problems that must be solved with solutions ad hoc. The analysis of 1 DH products was difficult (Figure 5). Albeit it is quite clear that they have the same fingerprints of MG, to obtain a clear fingerprint a higher concentration of the product should be necessary that would increase the negative influence of glycerine. Therefore, the best compromise must be found, depending from the analysed species and product.
Figure 5: HPTLC analysis of bud-derivative MG and 1 DHs. Visualization: UV 366 nm. Tracks: Aesculus hyppocastanum 1,1 DH, and 2, MG; Crataegus oxyacantha 3,1 DH, and 4, MG; Fraxinus exceksior 5,1 DH, and 6, MG; Pinus mugo 7,1 DH, and 8, MG; Alnus glutinosa, 9,1 DH, and 10, MG; 10 Rosa canina 11,1 DH, and 12, MG; Viscum album 13,1 DH, and 14, MG.
Although HPLC remains the current best analytical tool for organic substances, other instrumental possibilities have been proposed. Nowadays, HPTLC is ready to become one of the best methods for control of quality, purity, stability and identity, in one word chemical validation, of complex botanical products. Therefore, botanicals can be easily and simply compared using the fingerprint approach and presence of adulterants as well detected. Main default concerns the still high cost of instrumentation and main advantage consists into the clear and simple evidence of the understandable result typical of TLC, avoiding the limits derived by the use of too specialized analyses.
On the basis of the HPTLC analyses performed on plant staminal cells products, the following considerations can be proposed: a) HPTLC can be used to evidence the compositions of these products (MG), also in cases of complex mixtures, although low concentrations of 1 DH can constitute a limit b) the compositions of these products can be visualized and compared with those of the hydro-alcoholic extracts; c) the fingerprints of bud-derivatives (MG) and hydro-alcoholic extract (EI) of the same plant appear similar but not equal, confirming the differences due to the different raw materials and extraction process; d) the interference of glycerine can be limited owing to its segregation near the deposition line.
Therefore, now the reported medicinal activities of bud-derivatives can be related to the secondary metabolites constituents.
Verdeil JL, Alemanno L, Niemenak N, Tranbarger TJ (2007) Pluripotent versus totipotent plant stem cells: dependence versus autonomy? Trends Plant Sci 12: 245-252.
Gray J (2004) Paradigms of the evolution of programmed cell death. In Gray J (edn) Programmed cell death in plants. Boca Raton FL: CRC Press 1-20.
Savona M, Mattioli R, Nigro S, Falasca G, Della Rovere F, et al. (2012) Two SERK genes are markers of pluripotency in Cyclamen persicum Mill. J Exp Bot 63: 471-488.
Nicoletti M (2012) Nutraceuticals and Botanicals: overview and perspectives. Int J Food Sci Nutr 63: 2-6.
Italian Medicines Agency (Agenzia Italiana del Farmaco-AIFA) (2009) the use of medicines in Italy-National Report-Year (2008) Pensiero Scientifico Editore, Rome, Italy.
Waltham MS (1998) Roadmaps to Market: Commercializing Functional Foods and Nutraceuticals, Decision Resources Inc 5.
Brookes G (2010) Economic Impact Assessment of the European Union (EU)’s Nutrition and Health Claims Regulation on the EU food supplement sector and market, for the European Health Claims Alliance (EHCA).
Clydesdale FM (1997) A proposal for the establishment of scientific criteria for health claims for functional foods. Nutr Rev 55: 413-422.
Nicoletti M, Petitto V (2010) Contamination of herbal products determined by NMR fingerprint. Nat Prod Res 24: 1325-1329.
Nicoletti M (2011) HPTLC fingerprint: a modern approach for the analytical determination of botanicals. Rev Bras Farmacogn. 21: 818-823.
Nicoletti M (2011) Identification of Thiosildenafil in a Health Supplement. Nat Prod Commun 6: 1003-1004.
Kanan SM, Abu-Yousef IA, Gunasekar C, Abdo N, Narasimhan S (2009) Detection and Quantification of Synthetic Drugs in Herbal Slimming Formula. European Journal of Scientific Research 34: 348-357.
Henry P (1982) Gemmothérapie. Therapeutic plant extracts embryonic. B. Westerlo, Impr. Saint Norbert.
Pharmacopéè Francaise (1965) VII (Edn) Wolter Kluver France.
Reich E, Schibli A (2006) A High-performance thin-layer chromatography for the analysis of medicinal plants. Thieme Medical Publishers Inc.
Reich E, Widmer V (2009) Plant Analysis 2008-Planar Chromatography. Planta Med 75: 711-718.
Gallo FR, Multari G, Federici E, Palazzino G, Giambenedetti M, et al. (2011) Chemical fingerprinting of Equisetum arvense L. using HPTLC densitometry and HPLC. Nat Prod Res 25: 1261–1270.
Piccin A, Toniolo C, Nicoletti M (2012) Analytical tools for digestive plant extracts Nutrifoods 11: 29-35.
Nicoletti M (2012) The Modern Analytical determination of Botanicals and Similar Novel Natural Products by HPTLC Fingerprint Approach in Studies on Natural Product Chemistry. Bioactive Natural Products. Atta-ir-Rahman (Edn) Elsevier 37: 217-258.
Xie P, Chen S, Liang YZ, Wang X, Tian R, et al. (2006) Chromatographic fingerprint analysis-a rational approach for quality assessment of traditional Chinese Herbal medicine. J Chromatogr A 1112: 171-180.
TLC Atlas of Chinese Crude Drugs in Pharmacopoeia of the People’s Republic of China (2009) Chinese Pharmacopoeia Commission. People’s Medical Publishing House.
The United States Herbal Pharmacopoeia (31st Edn) The National Formulary, (26th edn) Rockville: The United States Pharmacopoeia Convention.
World Health Organization (1998) Quality control methods for herbal materials. WHO Library Cataloguing: Geneva.
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Perimeter 81 for
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Listeriosis Outbreak Claims Three Lives in Kansas
Mar 18, 2015 By Peterson & Associates, P.C.
The FDA issued a safety advisory last week after five cases of listeriosis, a dangerous illness caused by the listeria bacteria, were identified in Kansas. The patients all became ill after consuming Blue Bell ice cream products. They were admitted to the hospital for different reasons; at least three of them have died.
The patients consumed pre-packaged single-serve ice cream products and milkshakes distributed to the hospital.
Kansas health officials have been aware of potential listeriosis outbreaks since January 2014. It wasn’t until the health department in South Carolina tested and found traces of the bacteria in Blue Bell Creameries’ ice cream manufacturing facility.
The current outbreak has been traced back to a Blue Bell ice cream machine at a production facility in Texas. Officials in Kansas were able to use a national health database to identify the outbreak source.
Which Products Are Affected?
Blue Bell Creameries has released a list of all of the products that have been recalled.
Chocolate Chip Country Cookie
Great Divide Bar
Sour Pop Green Apple Bar
Cotton Candy Bar
Vanilla Stick Slices
Almond Bars
6 pack Cotton Candy Bars
6 pack Sour Pop Green Apple Bars
12 pack No Sugar Added Mooo Bars
If you have any of the listed products in your home, discard them immediately after taking a picture of the item and retaining your receipt in case anyone in your family falls ill.
Though the company has said that the contaminated products were not sold to grocery stores, it is possible that retail items were affected. It pays to be cautious.
How Can I Protect My Family?
The contaminated food products were stored in display cases and refrigerators in grocery and other retail stores. Parents should make sure to wash and sanitize all grocery items with warm water and soap. Additionally, by making sure that children avoid handling items and wash their hands after trips to the store, parents can avoid spreading germs throughout the home after a shopping trip.
Food Recall Attorneys
Food recall attorneys at Peterson & Associates, P.C.are committed to protecting the rights of injured consumers. Foodborne illnesses pose a particular danger to especially vulnerable children and elderly adults.
Food manufacturing companies are held to incredibly high standards, and when they fail in their duties, they need to be held responsible.
If you or a loved one has contracted a food borne illness, contact our firm immediately to defend your interests.
Categories: Class Action Lawyer
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Imprint: Arrow
Leslie Thomas
Summer 1940. The evacuation of Dunkirk proves that the British can rise to a challenge, even against seemingly insurmountable odds. But now the soldiers walk the streets of Dover, even wandering through Woolworths store, and take weary turns on the town's skating rink.
Life, despite the threat of invasion and the reality of bombing, must go on and people must take comfort where they find it. Toby Hendry, a fighter pilot, is awaiting orders when he meets Giselle, a young Frenchwoman who took the chance to flee occupied France with the English troops. Their love affair feels like a summer idyll, but can it withstand the forces of war?
Meanwhile, reserve naval commander Paul Instow has been called up to fight in a war for which he feels too old. Distracting him from his worries is Molly, a young Dover prostitute. Their relationship is tender and happy, but is this a love born from desperation or could it be something more permanent?
And then there are Harold, Spots and Boot, three boys desperate to fight the German invaders, armed only with catapults and a stolen Bren gun...
In Dover Beach Thomas chronicles the lives and loves of ordinary people in besiged Britain during these tense, but curiously elated days.
Ormerod's Landing
The Dearest And The Best
Chloe's Song
Waiting For The Day
The Complete Dangerous Davies
The Adventures of Goodnight and Loving
That Old Gang Of Mine
Orders For New York
Dangerous Davies And The Lonely Heart
Stand Up Virgin Soldiers
The Virgin Soldiers
Dangerous In Love
Soldiers and Lovers
In My Wildest Dreams
Onward Virgin Soldiers
The Magic Army
Dangerous Davies
Other Times
Tropic Of Ruislip
Kensington Heights
Born in Newport, Monmouthshire, 1931, Leslie Thomas is the son of a sailor who was lost of sea in 1943. His boyhood in an orphanage is evoked in This Time Next Week published in 1964. At sixteen, he became a reporter, before going on to do his national service. He won worldwide acclaim with his bestselling novel The Virgin Soldiers, which has achieved international sales of over two million copies. His next novel, Dover Beach, will be published by William Heinemann in November 2005.
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Op-Ed Supports Congestion Pricing for San Francisco
An opinion piece by Josh Wilson makes a case for a congestion pricing plan tailored specifically for the realities of living and working in San Francisco.
July 3, 2019, 11am PDT | James Brasuell | @CasualBrasuell
JEMLEN
"Safer streets, less pollution, better transit, bustling business districts — San Francisco can have it all," writes Josh Wilson to open an opinion piece published recently by the San Francisco Chronicle.
But like many other cities around the state and the country, increased amounts of driving and reduced transit ridership are producing congestion, carbon emissions, and air pollution. "Something needs to change, and somebody has to pay," concludes Wilson. "Congestion and zone pricing offer a path forward."
Interestingly, Wilson brackets land use as a means to the solutions sought by congestion pricing by mentioning the political and bureaucratic quagmire of planning and development policy in the city: "One solution is to build around transit rather than automobiles, but that process is bogged down in the eternal battle between preservationists and pro-density developers. We need to raise the stakes while they get their issues sorted out."
A key theme throughout the opinion piece is the specificity of the proposed congestion pricing plan. The proposal targets specific streets, with specific concession made for certain kinds of drivers, and concern for specific outcomes that could be desired less desirable consequences of a congestion pricing scheme.
As noted by Wilson, "touristy Lombard Street and hustling, bustling Market Street" are under consideration as test cases for congestion pricing, following in the footsteps of New York City in implementing a transportation policy previously only encountered in European cities. The Overton window for congestion pricing has also opened in other U.S. cities like Chicago, Seattle, and Los Angeles in recent months.
San Francisco needs congestion pricing — and not just for downtown driving
Published on Sunday, July 28, 2019 in The San Francisco Chronicle
Car-Centric Planning
Multi-modalism
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Granted 30 Church Gardens Rathmines Dublin 6
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Alberta to release part of its climate change plan ahead of Paris meeting
Premier Notley said the province's plan will put Alberta on what she calls a progressive and balanced path forward.
November 5, 2015 by The Canadian Press
Rachel Notley
EDMONTON — Alberta Premier Rachel Notley says her government hopes to release substantial parts of its climate-change policy about one week before she leaves later this month for a global conference in Paris.
Notley said the province’s plan will include very significant changes that will put Alberta on what she calls a progressive and balanced path forward.
“We are going to do what we think we can do to improve our record in a way that not only supports Albertans but supports Albertans for generations to come,” she said Nov. 4.
“But we are going to also do that in a balanced way that allows the industry to be healthy and prosperous.
“Not only does our economy depend on this but so frankly does the whole country’s.”
The United Nations summit on climate change is to take place in the French capital from Nov. 30 to Dec. 11.
The meeting is aimed at negotiating targets for reducing greenhouse gas emissions beyond 2020.
Notley said Prime Minister Justin Trudeau has talked about different provinces coming up with their own climate change plans.
She said it remains to be seen how close Alberta’s targets will mesh with any federal plan.
Notley said Alberta’s policy will not necessarily be the same as a province with lots of hydro power.
“We are going to do our part,” she said.
“I’m confident that at least at the outset that we will be able to establish a pretty effective partnership with the federal government on this.”
Under former prime minister Stephen Harper, Canada withdrew from the original Kyoto protocol on greenhouse gas emissions.
Canada is currently not close to meeting its subsequent Copenhagen commitment of slashing emissions by 17% by 2020.
Alberta climate change plan coming soon
Alberta won’t support federal climate change plans without a pipeline
Alberta premier says Canadians need progressive climate change plan
Wynne won’t guarantee release of climate change plan before legislature rises
EU predicts economic recovery at ‘modest pace’ next year
Enbridge expects Line 9 service delays to cut into 2015 earnings
Growth and uncertainty
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Home » The Greening of Plumbing
The Greening of Plumbing
The LEED program will change how plumbing professionals think about building design in terms of plumbing.
Issue: 9/02
The term "energy efficient" has never truly been applied to plumbing systems. In fact, terms such as "green," "sustainability" or "environmental" have sprung up around other utilities (gas, electric) to further complicate the issue as it relates to plumbing systems.
The new Leadership in Energy & Environmental Design (LEED) Program will change all that by solidifying definitions and actions for all utilities, including water. LEED defines a threshold for green buildings and introduces a tool to promote and guide comprehensive and integrated building design. LEED is performance-based where possible, compatible with standard design processes, self-evaluating, self-documenting, but not self-certifying. Certification is solely done by the U.S. Green Building Council (USGBC). The program will change how plumbing professionals think about building design in terms of plumbing. This article will explain LEED and discuss the implications from a plumbing point of view.
Born Within the U.S. Green Building Council
The USGBC is the nation's foremost coalition of leaders from across the building industry (architecture firms, engineering firms, builders, manufacturers, service contractors, government entities, real estate developers and owners) working to promote buildings that are environmentally responsible, profitable and healthy places to live and work (http://www.usgbc.org). The USGBC, formed in 1993, seeks to integrate non-residential building industry sectors, take the lead in market transformation and to educate owners and practitioners about the impact of "green" on buildings and our environment.
Why LEED Was Created
LEED was created by the USGBC to define "green" by providing a standard for measurement; prevent "greenwashing" (false or exaggerated claims); and promote whole-building, integrated design processes. It seeks to facilitate positive results for the environment, occupant health and financial return. As a comprehensive program, LEED seeks to establish design guidelines and recognize leaders who follow these guidelines, stimulating a kind of "green competition" among individuals. Ultimately, the program seeks to raise consumer awareness and transform the marketplace with an established, recognizable national "brand" of green.
For example, there are multiple economic benefits of a green design as far as plumbing is concerned. Green building projects that are well integrated and comprehensive in scope can result in lower or neutral project development costs. Rehabilitating an existing building can lower infrastructure and materials costs. Integrated design that has been "greened" can use the payback from some strategies to pay for others. Energy-efficient building envelopes can reduce equipment needs--downsizing some equipment, such as chillers, or eliminating equipment, such as perimeter heating. Using pervious paving and other runoff prevention strategies can reduce the size and cost of stormwater management structures.
In addition to lower project costs, operating costs will be reduced. Energy- and water-efficient buildings have been able to reduce their operating costs significantly. Use can be cut to less than half that of a traditional building by employing aggressive and well-integrated green design concepts. For example, a 1.0 gpf/4.0 Lpf flushing system for water closets and 0.5 gpf/1.8 Lpf urinal flush valve can make an enormous difference in water consumption for a building. Manufacturers have been working aggressively to refine and push the performance levels of tank-type toilets through the use of pressure-assist technology. Also, on-demand sensor faucets instead of slow-closing faucets cut usage in public restrooms by significant amounts. All add up to big savings.
The LEED Rating System
The development of LEED was initiated by the USGBC membership, representing all segments of the building industry, and was developed using a transparent process open to the public. Other international rating systems (European and Canadian) existed at that time and were reviewed before work on LEED began. The LEED standard was developed by USGBC members through volunteer committees, including work by the U.S. Department of Energy. LEED Version 2.0 is based on accepted energy/environmental principles and strikes a balance between known effective practices and emerging concepts. The rating system provides a framework to help move the U.S. building industry to more sustainable practices. It responds to the U.S. marketplace and to budgets of U.S. design practices.
Buildings seeking certification must be submitted by someone who is "LEED Certified" to qualify to a minimum standard in six main areas of building design. These areas are: 1) Sustainable Sites, 2) Water Efficiency, 3) Energy & Atmosphere, 4) Materials & Resources, 5) Indoor Environmental Quality, and 6) Innovation & Design Process.
In addition, prerequisites must be met in each of these six areas in order to qualify for any certification level. For example, the prerequisite for water in LEED is meeting the Federal Energy Act of 1992. To earn points toward certification levels, further reductions beyond the prerequisite have to be achieved.
The four levels of certification for buildings in the LEED program are:
LEED Certified 26 - 32 points
Silver Level 33 - 38 points
Gold Level 39 - 51 points
Platinum Level 52 + points (69 possible)
The total points achieved under LEED in these six areas determine the level of certification (minimum 26 points, maximum 69).
Water Efficiency Credits 3.1-3.2: Water Use Reduction
Credit 3 of the LEED Program, "Water Use Reduction," has maximizing water efficiency within buildings to reduce the burden on municipal water supply and wastewater systems as an objective. There are two possible credits. In Credit 3.1, building owners employ strategies that in aggregate use 20% less water than the water-use baseline calculated for the building (not including irrigation) after meeting Energy Policy Act of 1992 fixture performance requirements. To meet Credit 3.2, building owners reduce potable water by an additional 10% (30% total efficiency increase).
The 1.0 gpf/4.0 Lpf flushing system, which has recently been introduced into the United States, offers a significant way to meet this requirement. Traditional 1.6 gpf/6 Lpf flushing systems have been created to meet the Energy Policy Act of 1992 (minimum requirement for LEED). The new flushing system (at this writing, a pressure-assist unit) brings a 33% reduction in each flush, helping reach the reduction of potable water goals in LEED. In addition, a 0.5 gpf urinal flush valve can serve as a significant water conservation strategy. Also, on-demand sensor faucets serve as part of water conservation strategies. These faucets can save a high percentage of water while maximizing hygiene. In one application, for example, where year-old metering faucets were running water continuously, a changeout to sensor faucets produced an estimated 10 to 15% savings in water consumption.
Water Conservation Beyond LEED
In addition to LEED, engineers should reflect on water as a resource. The United States as a nation possesses abundant water resources, and has developed and used these resources extensively (the withdrawal of fresh and saline water in the United States during 1995 is estimated to have been 402,000 million gallons per day for all offstream uses--2% less than the 1990 estimate). The future health and economic welfare of our nation's population, however, are dependent upon a continuing supply of fresh uncontaminated water. Many existing sources of water are being stressed by withdrawals to meet offstream needs, along with increasing instream-flow requirements to meet human and environmental needs. Recent drought in some areas has accentuated the need to balance water demand with available supply. Approximately 339,000 million gallons per day of freshwater (about one quarter of the national renewable supply) were withdrawn during 1990 for use by the nation's homes, farms and industries, and about 220 billion gallons per day were returned to streams after use (U.S. Geological Survey (USGS)).
The following reasons are sound strategies for engineers to promote LEED objectives in the Water Use Reduction part of the program:
One half of the world's population lives and works in urban areas--a geographical concentration further intensified because demands are typically met through central water supply systems that bring water to only a few locations for treatment.
In many of these areas, urban demands cannot be met with local supplies, and additional water has to be imported from distant sources, implying that as urban populations increase, the economic costs of water supply will also increase.
The environmental impacts of urban water supply will intensify, as the "ecological footprint" of urban areas extends a long distance upstream and also some distance downstream when the partially treated or untreated sewage is discharged to watercourses or the sea.
A total of 32 states reported drought conditions in March 2002!
Commercial water use, which LEED strives to control, includes water used by commercial facilities such as hotels, motels, restaurants, office buildings, government and military facilities, hospitals, educational institutions and retail sales stores. Commercial water use in office buildings primarily is used for sanitation, maintenance and aesthetic appeal. Specific uses of water include toilet flushing, air-conditioning, washing floors and other surfaces, fountains and lawn watering.
The Use of Graywater Systems
The next wave of water conservation strategy is a logical progression to LEED and will include uses of graywater. Graywater is of a lesser quality than potable water but of higher quality than blackwater. While graywater is most suitably used for subsurface irrigation of non-edible landscape plants, its applications are expanding. In a commercial application, for example, chiller water can be directed to the plumbing system through filter techniques. While somewhat cost-prohibitive today, techniques to accomplish this are continually being refined and made more cost-effective.
Graywater offers potential financial advantages to regional sewage treatment facilities, since its use diminishes sewer flows and lessens the need to expand such facilities. For example, the state of California now allows graywater systems, and various municipalities and utility districts have passed specific graywater ordinances. The installation of graywater systems requires modifications to existing plumbing systems and the addition of certain components.
People are going to be asked to change their habits in many areas as LEED takes hold. Energy efficiency has always meant a change of life habits to a population. Cars using less fuel meant people had to get used to lower performance. The rolling blackouts in California used to conserve energy meant people had to adjust their lives accordingly. The more a product can maintain the habits of a population and conserve energy, the more acceptance that product will have. In other words, products that do not sacrifice performance, yet do conserve energy, will have a higher acceptance than those that give up performance in favor of energy efficiency.
In terms of water, for example, all "energy-efficient" products will be examined according to this point of view. The flushless fixtures promise maximum water conservation--but at a price of increased daily maintenance and increased hygiene risks. Four-Liter toilets reduce water consumption, but without requiring a habit change on the part of users. In both cases, plumbing engineers have to evaluate the contribution to a LEED certification goal while keeping in mind the habits of the people who will utilize these devices.
Buildings in the future are going to be increasingly designed with the LEED point of view in mind, and all types of products will be examined very carefully. It is to the plumbing engineer's benefit not only to learn about the program, but also to begin incorporating its strategies into the day-to-day routines of designing plumbing systems for buildings.
SIDEBAR: Getting Started With LEED
Since the release of LEED 2.0 in March 2000, project teams from more than 275 projects have registered their buildings, expressing their intent to apply for official LEED Certification by the USGBC. Increasingly, companies are turning to LEED as the blueprint by which a true "green building" can be designed.
LEED is a registered trademark of USGBC. Only buildings certified by USGBC under the LEED Green Building Rating System may refer to themselves as LEED buildings. The certification process involves the following:
1. Register the project to initiate a relationship with USGBC and receive orientation materials. Registration during pre-design phase is highly recommended.
2. Technical support comes in the form of the Reference Guide and Credit Rulings. In some cases, the design team may encounter questions about the application of a LEED prerequisite or credit to the specifics of their project. The project contact should first thoroughly consult the Reference Guide. If questions remain, the contact should use the following credit interpretation procedure:
The project contact reviews the intent of the credit or prerequisite in question to self-evaluate whether their project meets this intent.
The project contact reviews the LEED Credit Rulings Page for a previously logged Credit Interpretation Request (CIR) that may assist in answering their particular question. All LEED project contacts have access to this page.
If no similar or relevant credit interpretation has been logged, then the project contact may submit an online CIR to the USGBC.
Within two to five weeks, the USGBC Credit Ruling Committee posts its decision on the Credit Rulings Page.
3. Apply for certification. Application review can take anywhere from six weeks to several months. There are several opportunities for response and appeal throughout the review stages (administrative, preliminary technical and final technical reviews).
Also, consider the following:
The LEED Rating System is available for free download from the USGBC Web site (http://www.usgbc.org), along with the LEED checklist and summaries of the documentation requirements and the referenced standards.
The LEED Reference Package, available for purchase on http://www.LEEDbuilding.org contains an essential set of tools for green building and LEED certification. It includes the 270-page Reference Guide, the Welcome Packet, LEED Calculator spreadsheets, Application Template, Introductory Slideshow, the Rating System and the Accreditation Exam Study Guide. The Reference Guide is a design assistance manual and LEED user's manual. For each credit, it discusses green building concerns, a summary of any standards that are part of the credit or prerequisite, strategies and resources for achieving it, potential synergies and trade-offs with other credits and strategies, calculations and documentation requirements. Where possible, cost estimates and case studies are provided.
The Registered Project Welcome Packet provides instruction for LEED documentation and various tools, such as samples, calculation spreadsheets and a template to facilitate project management and the certification process.
The LEED Reference Package
USGBC
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Check out the January 2020 edition of pme: Numerous innovative mechanical systems installed at the University of Iowa’s Visual Arts Center in Iowa City, Software integration takes BIM to next level, take a look at commercial HVAC trends, and much more!
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Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family
H B Jefferies, C Reinhard, S C Kozma, and G Thomas
PNAS May 10, 1994 91 (10) 4441-4445; https://doi.org/10.1073/pnas.91.10.4441
H B Jefferies
C Reinhard
S C Kozma
G Thomas
The immunosuppressant rapamycin blocks p70s6k/p85s6k activation and phosphorylation of 40S ribosomal protein S6 in Swiss 3T3 cells. The same net result is obtained when the macrolide is added 3 hr after serum stimulation. In stimulated cells p70s6k/p85s6k inactivation is achieved within minutes, whereas S6 dephosphorylation requires 1-2 hr, supporting the concept that S6 dephosphorylation results from kinase inactivation. In parallel, rapamycin treatment causes a small, but significant, reduction in the initiation rate of protein synthesis, as measured both by [35S]methionine incorporation into protein and by recruitment of 80S ribosomes into polysomes. More striking, analysis of individual mRNA transcripts revealed that rapamycin selectively suppresses the translation of a family of mRNAs that is characterized by a polypyrimidine tract immediately after their N7-methylguanosine cap, a motif that can act as a translational modulator. This family includes transcripts for ribosomal proteins, elongation factors of protein synthesis, and proteins of as-yet-unknown function. The results imply that (i) 40S ribosomes containing phosphorylated S6 may selectively recognize this motif or proteins which bind to it and (ii) rapamycin may inhibit cell growth by blocking S6 phosphorylation and, thus, translation of these mRNAs.
You are going to email the following Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family
H B Jefferies, C Reinhard, S C Kozma, G Thomas
Proceedings of the National Academy of Sciences May 1994, 91 (10) 4441-4445; DOI: 10.1073/pnas.91.10.4441
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